Result of FASTA (omim) for
pF1KB3457
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3457, 176 aa
1>>>pF1KB3457 176 - 176 aa - 176 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.6134+/-0.000324; mu= 2.6835+/- 0.020
mean_var=137.2363+/-27.467, 0's: 0 Z-trim(119.4): 17 B-trim: 0 in 0/56
Lambda= 0.109481
statistics sampled from 33379 (33396) to 33379 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.738), E-opt: 0.2 (0.392), width: 16
Scan time: 6.150
The best scores are: opt bits E(85289)
NP_001929 (OMIM: 601482) protein Dr1 [Homo sapiens ( 176) 1112 186.1 2.5e-47
NP_006157 (OMIM: 189904) nuclear transcription fac ( 207) 253 50.5 2e-06
XP_005268966 (OMIM: 189904) PREDICTED: nuclear tra ( 208) 253 50.5 2e-06
XP_005268965 (OMIM: 189904) PREDICTED: nuclear tra ( 208) 253 50.5 2e-06
XP_005268967 (OMIM: 189904) PREDICTED: nuclear tra ( 208) 253 50.5 2e-06
NP_001265184 (OMIM: 607267) DNA polymerase epsilon ( 147) 182 39.2 0.0036
NP_059139 (OMIM: 607267) DNA polymerase epsilon su ( 147) 182 39.2 0.0036
>>NP_001929 (OMIM: 601482) protein Dr1 [Homo sapiens] (176 aa)
initn: 1112 init1: 1112 opt: 1112 Z-score: 970.6 bits: 186.1 E(85289): 2.5e-47
Smith-Waterman score: 1112; 100.0% identity (100.0% similar) in 176 aa overlap (1-176:1-176)
10 20 30 40 50 60
pF1KB3 MASSSGNDDDLTIPRAAINKMIKETLPNVRVANDARELVVNCCTEFIHLISSEANEICNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MASSSGNDDDLTIPRAAINKMIKETLPNVRVANDARELVVNCCTEFIHLISSEANEICNK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 SEKKTISPEHVIQALESLGFGSYISEVKEVLQECKTVALKRRKASSRLENLGIPEEELLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SEKKTISPEHVIQALESLGFGSYISEVKEVLQECKTVALKRRKASSRLENLGIPEEELLR
70 80 90 100 110 120
130 140 150 160 170
pF1KB3 QQQELFAKARQQQAELAQQEWLQMQQAAQQAQLAAASASASNQAGSSQDEEDDDDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQQELFAKARQQQAELAQQEWLQMQQAAQQAQLAAASASASNQAGSSQDEEDDDDI
130 140 150 160 170
>>NP_006157 (OMIM: 189904) nuclear transcription factor (207 aa)
initn: 236 init1: 195 opt: 253 Z-score: 236.3 bits: 50.5 E(85289): 2e-06
Smith-Waterman score: 253; 31.6% identity (65.8% similar) in 155 aa overlap (8-154:54-207)
10 20 30
pF1KB3 MASSSGNDDDLTIPRAAINKMIKETLPNV-RVANDAR
..:. .: : . ...:...:.. ..:.::.
NP_006 GSHYVIQPHDDTEDSMNDHEDTNGSKESFREQDIYLPIANVARIMKNAIPQTGKIAKDAK
30 40 50 60 70 80
40 50 60 70 80 90
pF1KB3 ELVVNCCTEFIHLISSEANEICNKSEKKTISPEHVIQALESLGFGSYISEVKEVLQECKT
: : .: .::: .:.:::.: :.. ..:::. : .. :. .::: ::. .: ::. .
NP_006 ECVQECVSEFISFITSEASERCHQEKRKTINGEDILFAMSTLGFDSYVEPLKLYLQKFRE
90 100 110 120 130 140
100 110 120 130 140
pF1KB3 VALKRRK----ASSRLENLG--IPEEELLRQQQE-LFAKARQQQAELAQQEWLQMQQAAQ
:.: .: : . ..:. . :: . : :.. ::: .. :. ...:
NP_006 -AMKGEKGIGGAVTATDGLSEELTEEAFTNQLPAGLITTDGQQQNVMVYTTSYQQISGVQ
150 160 170 180 190 200
150 160 170
pF1KB3 QAQLAAASASASNQAGSSQDEEDDDDI
: :..
NP_006 QIQFS
>>XP_005268966 (OMIM: 189904) PREDICTED: nuclear transcr (208 aa)
initn: 236 init1: 195 opt: 253 Z-score: 236.3 bits: 50.5 E(85289): 2e-06
Smith-Waterman score: 253; 31.6% identity (65.8% similar) in 155 aa overlap (8-154:55-208)
10 20 30
pF1KB3 MASSSGNDDDLTIPRAAINKMIKETLPNV-RVANDAR
..:. .: : . ...:...:.. ..:.::.
XP_005 GSHYVIQPHDDTEDSMNDHEDTNGSKESFREQDIYLPIANVARIMKNAIPQTGKIAKDAK
30 40 50 60 70 80
40 50 60 70 80 90
pF1KB3 ELVVNCCTEFIHLISSEANEICNKSEKKTISPEHVIQALESLGFGSYISEVKEVLQECKT
: : .: .::: .:.:::.: :.. ..:::. : .. :. .::: ::. .: ::. .
XP_005 ECVQECVSEFISFITSEASERCHQEKRKTINGEDILFAMSTLGFDSYVEPLKLYLQKFRE
90 100 110 120 130 140
100 110 120 130 140
pF1KB3 VALKRRK----ASSRLENLG--IPEEELLRQQQE-LFAKARQQQAELAQQEWLQMQQAAQ
:.: .: : . ..:. . :: . : :.. ::: .. :. ...:
XP_005 -AMKGEKGIGGAVTATDGLSEELTEEAFTNQLPAGLITTDGQQQNVMVYTTSYQQISGVQ
150 160 170 180 190 200
150 160 170
pF1KB3 QAQLAAASASASNQAGSSQDEEDDDDI
: :..
XP_005 QIQFS
>>XP_005268965 (OMIM: 189904) PREDICTED: nuclear transcr (208 aa)
initn: 236 init1: 195 opt: 253 Z-score: 236.3 bits: 50.5 E(85289): 2e-06
Smith-Waterman score: 253; 31.6% identity (65.8% similar) in 155 aa overlap (8-154:55-208)
10 20 30
pF1KB3 MASSSGNDDDLTIPRAAINKMIKETLPNV-RVANDAR
..:. .: : . ...:...:.. ..:.::.
XP_005 GSHYVIQPHDDTEDSMNDHEDTNGSKESFREQDIYLPIANVARIMKNAIPQTGKIAKDAK
30 40 50 60 70 80
40 50 60 70 80 90
pF1KB3 ELVVNCCTEFIHLISSEANEICNKSEKKTISPEHVIQALESLGFGSYISEVKEVLQECKT
: : .: .::: .:.:::.: :.. ..:::. : .. :. .::: ::. .: ::. .
XP_005 ECVQECVSEFISFITSEASERCHQEKRKTINGEDILFAMSTLGFDSYVEPLKLYLQKFRE
90 100 110 120 130 140
100 110 120 130 140
pF1KB3 VALKRRK----ASSRLENLG--IPEEELLRQQQE-LFAKARQQQAELAQQEWLQMQQAAQ
:.: .: : . ..:. . :: . : :.. ::: .. :. ...:
XP_005 -AMKGEKGIGGAVTATDGLSEELTEEAFTNQLPAGLITTDGQQQNVMVYTTSYQQISGVQ
150 160 170 180 190 200
150 160 170
pF1KB3 QAQLAAASASASNQAGSSQDEEDDDDI
: :..
XP_005 QIQFS
>>XP_005268967 (OMIM: 189904) PREDICTED: nuclear transcr (208 aa)
initn: 236 init1: 195 opt: 253 Z-score: 236.3 bits: 50.5 E(85289): 2e-06
Smith-Waterman score: 253; 31.6% identity (65.8% similar) in 155 aa overlap (8-154:55-208)
10 20 30
pF1KB3 MASSSGNDDDLTIPRAAINKMIKETLPNV-RVANDAR
..:. .: : . ...:...:.. ..:.::.
XP_005 GSHYVIQPHDDTEDSMNDHEDTNGSKESFREQDIYLPIANVARIMKNAIPQTGKIAKDAK
30 40 50 60 70 80
40 50 60 70 80 90
pF1KB3 ELVVNCCTEFIHLISSEANEICNKSEKKTISPEHVIQALESLGFGSYISEVKEVLQECKT
: : .: .::: .:.:::.: :.. ..:::. : .. :. .::: ::. .: ::. .
XP_005 ECVQECVSEFISFITSEASERCHQEKRKTINGEDILFAMSTLGFDSYVEPLKLYLQKFRE
90 100 110 120 130 140
100 110 120 130 140
pF1KB3 VALKRRK----ASSRLENLG--IPEEELLRQQQE-LFAKARQQQAELAQQEWLQMQQAAQ
:.: .: : . ..:. . :: . : :.. ::: .. :. ...:
XP_005 -AMKGEKGIGGAVTATDGLSEELTEEAFTNQLPAGLITTDGQQQNVMVYTTSYQQISGVQ
150 160 170 180 190 200
150 160 170
pF1KB3 QAQLAAASASASNQAGSSQDEEDDDDI
: :..
XP_005 QIQFS
>>NP_001265184 (OMIM: 607267) DNA polymerase epsilon sub (147 aa)
initn: 195 init1: 119 opt: 182 Z-score: 177.9 bits: 39.2 E(85289): 0.0036
Smith-Waterman score: 182; 29.6% identity (68.4% similar) in 98 aa overlap (9-105:6-103)
10 20 30 40 50
pF1KB3 MASSSGNDDDLTIPRAAINKMIKETLPN-VRVANDARELVVNCCTEFIHLISSEANEICN
.::..: :.:...:::.::. : ....:: . . :. .: ::..
NP_001 MAERPEDLNLPNAVITRIIKEALPDGVNISKEARSAISRAASVFVLYATSCANNFAM
10 20 30 40 50
60 70 80 90 100 110
pF1KB3 KSEKKTISPEHVIQALESLGFGSYISEVKEVLQECKTVALKRRKASSRLENLGIPEEELL
:...::.. :..:.: . : ... .::.:. . ...::
NP_001 KGKRKTLNASDVLSAMEEMEFQRFVTPLKEALEAYRREQKGKKEASEQKKKDKDKKTDSE
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB3 RQQQELFAKARQQQAELAQQEWLQMQQAAQQAQLAAASASASNQAGSSQDEEDDDDI
NP_001 EQDKSRDEDNDEDEERLEEEEQNEEEEVDN
120 130 140
>>NP_059139 (OMIM: 607267) DNA polymerase epsilon subuni (147 aa)
initn: 195 init1: 119 opt: 182 Z-score: 177.9 bits: 39.2 E(85289): 0.0036
Smith-Waterman score: 182; 29.6% identity (68.4% similar) in 98 aa overlap (9-105:6-103)
10 20 30 40 50
pF1KB3 MASSSGNDDDLTIPRAAINKMIKETLPN-VRVANDARELVVNCCTEFIHLISSEANEICN
.::..: :.:...:::.::. : ....:: . . :. .: ::..
NP_059 MAERPEDLNLPNAVITRIIKEALPDGVNISKEARSAISRAASVFVLYATSCANNFAM
10 20 30 40 50
60 70 80 90 100 110
pF1KB3 KSEKKTISPEHVIQALESLGFGSYISEVKEVLQECKTVALKRRKASSRLENLGIPEEELL
:...::.. :..:.: . : ... .::.:. . ...::
NP_059 KGKRKTLNASDVLSAMEEMEFQRFVTPLKEALEAYRREQKGKKEASEQKKKDKDKKTDSE
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB3 RQQQELFAKARQQQAELAQQEWLQMQQAAQQAQLAAASASASNQAGSSQDEEDDDDI
NP_059 EQDKSRDEDNDEDEERLEEEEQNEEEEVDN
120 130 140
176 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 13:17:18 2016 done: Thu Nov 3 13:17:19 2016
Total Scan time: 6.150 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]