Result of FASTA (omim) for pF1KB3107
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB3107, 165 aa
  1>>>pF1KB3107 165 - 165 aa - 165 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.2872+/-0.00028; mu= 13.5763+/- 0.018
 mean_var=101.9788+/-21.673, 0's: 0 Z-trim(121.7): 341  B-trim: 2036 in 1/51
 Lambda= 0.127005
 statistics sampled from 38150 (38576) to 38150 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.798), E-opt: 0.2 (0.452), width:  16
 Scan time:  5.240

The best scores are:                                      opt bits E(85289)
XP_005271348 (OMIM: 603129) PREDICTED: LIM domain  ( 165) 1202 229.5 1.9e-60
NP_006760 (OMIM: 603129) LIM domain transcription  ( 165) 1202 229.5 1.9e-60
XP_011518401 (OMIM: 186921) PREDICTED: rhombotin-1 ( 145)  554 110.7 9.5e-25
XP_011518400 (OMIM: 186921) PREDICTED: rhombotin-1 ( 145)  554 110.7 9.5e-25
NP_001257357 (OMIM: 186921) rhombotin-1 isoform b  ( 155)  554 110.8   1e-24
NP_002306 (OMIM: 186921) rhombotin-1 isoform a [Ho ( 156)  554 110.8   1e-24
XP_006718291 (OMIM: 186921) PREDICTED: rhombotin-1 ( 193)  554 110.9 1.2e-24
NP_001230538 (OMIM: 180386) LIM domain only protei ( 145)  539 108.0 6.4e-24
XP_006719173 (OMIM: 180386) PREDICTED: LIM domain  ( 145)  539 108.0 6.4e-24
XP_011519065 (OMIM: 180386) PREDICTED: LIM domain  ( 145)  539 108.0 6.4e-24
NP_001001395 (OMIM: 180386) LIM domain only protei ( 145)  539 108.0 6.4e-24
XP_011519064 (OMIM: 180386) PREDICTED: LIM domain  ( 145)  539 108.0 6.4e-24
XP_006719174 (OMIM: 180386) PREDICTED: LIM domain  ( 145)  539 108.0 6.4e-24
NP_061110 (OMIM: 180386) LIM domain only protein 3 ( 145)  539 108.0 6.4e-24
NP_001230539 (OMIM: 180386) LIM domain only protei ( 145)  539 108.0 6.4e-24
NP_001230540 (OMIM: 180386) LIM domain only protei ( 156)  539 108.0 6.7e-24
NP_001230541 (OMIM: 180386) LIM domain only protei ( 163)  539 108.0 6.9e-24
NP_001135787 (OMIM: 180385) rhombotin-2 isoform 2  ( 158)  451 91.9 4.8e-19
XP_016873222 (OMIM: 180385) PREDICTED: rhombotin-2 ( 158)  451 91.9 4.8e-19
NP_001135788 (OMIM: 180385) rhombotin-2 isoform 2  ( 158)  451 91.9 4.8e-19
XP_016873219 (OMIM: 180385) PREDICTED: rhombotin-2 ( 158)  451 91.9 4.8e-19
XP_016873220 (OMIM: 180385) PREDICTED: rhombotin-2 ( 158)  451 91.9 4.8e-19
XP_016873218 (OMIM: 180385) PREDICTED: rhombotin-2 ( 158)  451 91.9 4.8e-19
XP_016873216 (OMIM: 180385) PREDICTED: rhombotin-2 ( 158)  451 91.9 4.8e-19
XP_005252978 (OMIM: 180385) PREDICTED: rhombotin-2 ( 158)  451 91.9 4.8e-19
XP_016873217 (OMIM: 180385) PREDICTED: rhombotin-2 ( 158)  451 91.9 4.8e-19
XP_016873221 (OMIM: 180385) PREDICTED: rhombotin-2 ( 158)  451 91.9 4.8e-19
NP_005565 (OMIM: 180385) rhombotin-2 isoform 1 [Ho ( 227)  451 92.1 6.2e-19
NP_203129 (OMIM: 262700,602146) LIM/homeobox prote ( 390)  427 87.9 1.9e-17
XP_005245407 (OMIM: 606066) PREDICTED: LIM/homeobo ( 336)  426 87.7 1.9e-17
XP_016857338 (OMIM: 606066) PREDICTED: LIM/homeobo ( 378)  426 87.7 2.1e-17
NP_001014434 (OMIM: 606066) LIM/homeobox protein L ( 388)  426 87.7 2.1e-17
NP_064589 (OMIM: 606066) LIM/homeobox protein Lhx9 ( 397)  426 87.7 2.2e-17
XP_011508083 (OMIM: 606066) PREDICTED: LIM/homeobo ( 403)  426 87.8 2.2e-17
XP_006717386 (OMIM: 603759) PREDICTED: LIM/homeobo ( 314)  417 86.0 5.8e-17
NP_004780 (OMIM: 603759) LIM/homeobox protein Lhx2 ( 406)  417 86.1 6.8e-17
XP_016870657 (OMIM: 221750,600577) PREDICTED: LIM/ ( 373)  405 83.9   3e-16
XP_005263467 (OMIM: 221750,600577) PREDICTED: LIM/ ( 386)  405 83.9   3e-16
NP_835258 (OMIM: 221750,600577) LIM/homeobox prote ( 397)  405 83.9 3.1e-16
NP_055379 (OMIM: 221750,600577) LIM/homeobox prote ( 402)  405 83.9 3.1e-16
NP_665804 (OMIM: 609481) insulin gene enhancer pro ( 359)  395 82.0   1e-15
XP_016877994 (OMIM: 609481) PREDICTED: insulin gen ( 534)  395 82.2 1.3e-15
NP_071758 (OMIM: 605992) LIM/homeobox protein Lhx5 ( 402)  388 80.8 2.7e-15
NP_001243043 (OMIM: 604425) LIM/homeobox protein L ( 346)  387 80.5 2.8e-15
NP_001001933 (OMIM: 604425) LIM/homeobox protein L ( 356)  387 80.5 2.8e-15
XP_016856806 (OMIM: 604425) PREDICTED: LIM/homeobo ( 363)  387 80.6 2.9e-15
XP_016856805 (OMIM: 604425) PREDICTED: LIM/homeobo ( 363)  387 80.6 2.9e-15
XP_005251973 (OMIM: 608215) PREDICTED: LIM/homeobo ( 230)  382 79.4   4e-15
NP_001229263 (OMIM: 608215) LIM/homeobox protein L ( 363)  382 79.6 5.4e-15
NP_001229262 (OMIM: 608215) LIM/homeobox protein L ( 366)  382 79.6 5.4e-15


>>XP_005271348 (OMIM: 603129) PREDICTED: LIM domain tran  (165 aa)
 initn: 1202 init1: 1202 opt: 1202  Z-score: 1206.3  bits: 229.5 E(85289): 1.9e-60
Smith-Waterman score: 1202; 100.0% identity (100.0% similar) in 165 aa overlap (1-165:1-165)

               10        20        30        40        50        60
pF1KB3 MVNPGSSSQPPPVTAGSLSWKRCAGCGGKIADRFLLYAMDSYWHSRCLKCSCCQAQLGDI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MVNPGSSSQPPPVTAGSLSWKRCAGCGGKIADRFLLYAMDSYWHSRCLKCSCCQAQLGDI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 GTSCYTKSGMILCRNDYIRLFGNSGACSACGQSIPASELVMRAQGNVYHLKCFTCSTCRN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GTSCYTKSGMILCRNDYIRLFGNSGACSACGQSIPASELVMRAQGNVYHLKCFTCSTCRN
               70        80        90       100       110       120

              130       140       150       160     
pF1KB3 RLVPGDRFHYINGSLFCEHDRPTALINGHLNSLQSNPLLPDQKVC
       :::::::::::::::::::::::::::::::::::::::::::::
XP_005 RLVPGDRFHYINGSLFCEHDRPTALINGHLNSLQSNPLLPDQKVC
              130       140       150       160     

>>NP_006760 (OMIM: 603129) LIM domain transcription fact  (165 aa)
 initn: 1202 init1: 1202 opt: 1202  Z-score: 1206.3  bits: 229.5 E(85289): 1.9e-60
Smith-Waterman score: 1202; 100.0% identity (100.0% similar) in 165 aa overlap (1-165:1-165)

               10        20        30        40        50        60
pF1KB3 MVNPGSSSQPPPVTAGSLSWKRCAGCGGKIADRFLLYAMDSYWHSRCLKCSCCQAQLGDI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MVNPGSSSQPPPVTAGSLSWKRCAGCGGKIADRFLLYAMDSYWHSRCLKCSCCQAQLGDI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 GTSCYTKSGMILCRNDYIRLFGNSGACSACGQSIPASELVMRAQGNVYHLKCFTCSTCRN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 GTSCYTKSGMILCRNDYIRLFGNSGACSACGQSIPASELVMRAQGNVYHLKCFTCSTCRN
               70        80        90       100       110       120

              130       140       150       160     
pF1KB3 RLVPGDRFHYINGSLFCEHDRPTALINGHLNSLQSNPLLPDQKVC
       :::::::::::::::::::::::::::::::::::::::::::::
NP_006 RLVPGDRFHYINGSLFCEHDRPTALINGHLNSLQSNPLLPDQKVC
              130       140       150       160     

>>XP_011518401 (OMIM: 186921) PREDICTED: rhombotin-1 iso  (145 aa)
 initn: 635 init1: 551 opt: 554  Z-score: 565.3  bits: 110.7 E(85289): 9.5e-25
Smith-Waterman score: 554; 52.3% identity (78.8% similar) in 132 aa overlap (21-152:11-142)

               10        20        30        40        50        60
pF1KB3 MVNPGSSSQPPPVTAGSLSWKRCAGCGGKIADRFLLYAMDSYWHSRCLKCSCCQAQLGDI
                           : ::::. :: ::.:: :.:.:::  ::::.::. .::..
XP_011           MLSVQPKGKQKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEV
                         10        20        30        40        50

               70        80        90       100       110       120
pF1KB3 GTSCYTKSGMILCRNDYIRLFGNSGACSACGQSIPASELVMRAQGNVYHLKCFTCSTCRN
       :.. :::...:::: ::.::::..: :.::.. ::: :.::::. ::::: ::.:. : .
XP_011 GSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCNQ
               60        70        80        90       100       110

              130       140       150       160     
pF1KB3 RLVPGDRFHYINGSLFCEHDRPTALINGHLNSLQSNPLLPDQKVC
       :.  ::.:   :. ..:. :   . .:: ..:             
XP_011 RFCVGDKFFLKNNMILCQMDYEEGQLNGTFESQVQ          
              120       130       140               

>>XP_011518400 (OMIM: 186921) PREDICTED: rhombotin-1 iso  (145 aa)
 initn: 635 init1: 551 opt: 554  Z-score: 565.3  bits: 110.7 E(85289): 9.5e-25
Smith-Waterman score: 554; 52.3% identity (78.8% similar) in 132 aa overlap (21-152:11-142)

               10        20        30        40        50        60
pF1KB3 MVNPGSSSQPPPVTAGSLSWKRCAGCGGKIADRFLLYAMDSYWHSRCLKCSCCQAQLGDI
                           : ::::. :: ::.:: :.:.:::  ::::.::. .::..
XP_011           MLSVQPKGKQKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEV
                         10        20        30        40        50

               70        80        90       100       110       120
pF1KB3 GTSCYTKSGMILCRNDYIRLFGNSGACSACGQSIPASELVMRAQGNVYHLKCFTCSTCRN
       :.. :::...:::: ::.::::..: :.::.. ::: :.::::. ::::: ::.:. : .
XP_011 GSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCNQ
               60        70        80        90       100       110

              130       140       150       160     
pF1KB3 RLVPGDRFHYINGSLFCEHDRPTALINGHLNSLQSNPLLPDQKVC
       :.  ::.:   :. ..:. :   . .:: ..:             
XP_011 RFCVGDKFFLKNNMILCQMDYEEGQLNGTFESQVQ          
              120       130       140               

>>NP_001257357 (OMIM: 186921) rhombotin-1 isoform b [Hom  (155 aa)
 initn: 638 init1: 554 opt: 554  Z-score: 564.9  bits: 110.8 E(85289): 1e-24
Smith-Waterman score: 554; 52.3% identity (78.8% similar) in 132 aa overlap (21-152:21-152)

               10        20        30        40        50        60
pF1KB3 MVNPGSSSQPPPVTAGSLSWKRCAGCGGKIADRFLLYAMDSYWHSRCLKCSCCQAQLGDI
                           : ::::. :: ::.:: :.:.:::  ::::.::. .::..
NP_001 MVLDQEDGVPMLSVQPKGKQKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 GTSCYTKSGMILCRNDYIRLFGNSGACSACGQSIPASELVMRAQGNVYHLKCFTCSTCRN
       :.. :::...:::: ::.::::..: :.::.. ::: :.::::. ::::: ::.:. : .
NP_001 GSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCNQ
               70        80        90       100       110       120

              130       140       150       160     
pF1KB3 RLVPGDRFHYINGSLFCEHDRPTALINGHLNSLQSNPLLPDQKVC
       :.  ::.:   :. ..:. :   . .:: ..:             
NP_001 RFCVGDKFFLKNNMILCQMDYEEGQLNGTFESQVQ          
              130       140       150               

>>NP_002306 (OMIM: 186921) rhombotin-1 isoform a [Homo s  (156 aa)
 initn: 638 init1: 554 opt: 554  Z-score: 564.9  bits: 110.8 E(85289): 1e-24
Smith-Waterman score: 554; 52.3% identity (78.8% similar) in 132 aa overlap (21-152:22-153)

                10        20        30        40        50         
pF1KB3  MVNPGSSSQPPPVTAGSLSWKRCAGCGGKIADRFLLYAMDSYWHSRCLKCSCCQAQLGD
                            : ::::. :: ::.:: :.:.:::  ::::.::. .::.
NP_002 MMVLDKEDGVPMLSVQPKGKQKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGE
               10        20        30        40        50        60

      60        70        80        90       100       110         
pF1KB3 IGTSCYTKSGMILCRNDYIRLFGNSGACSACGQSIPASELVMRAQGNVYHLKCFTCSTCR
       .:.. :::...:::: ::.::::..: :.::.. ::: :.::::. ::::: ::.:. : 
NP_002 VGSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCN
               70        80        90       100       110       120

     120       130       140       150       160     
pF1KB3 NRLVPGDRFHYINGSLFCEHDRPTALINGHLNSLQSNPLLPDQKVC
       .:.  ::.:   :. ..:. :   . .:: ..:             
NP_002 QRFCVGDKFFLKNNMILCQMDYEEGQLNGTFESQVQ          
              130       140       150                

>>XP_006718291 (OMIM: 186921) PREDICTED: rhombotin-1 iso  (193 aa)
 initn: 601 init1: 551 opt: 554  Z-score: 563.8  bits: 110.9 E(85289): 1.2e-24
Smith-Waterman score: 554; 52.3% identity (78.8% similar) in 132 aa overlap (21-152:59-190)

                         10        20        30        40        50
pF1KB3           MVNPGSSSQPPPVTAGSLSWKRCAGCGGKIADRFLLYAMDSYWHSRCLKC
                                     : ::::. :: ::.:: :.:.:::  ::::
XP_006 GEVDVLGWKSGLGGAHWGVPMLSVQPKGKQKGCAGCNRKIKDRYLLKALDKYWHEDCLKC
       30        40        50        60        70        80        

               60        70        80        90       100       110
pF1KB3 SCCQAQLGDIGTSCYTKSGMILCRNDYIRLFGNSGACSACGQSIPASELVMRAQGNVYHL
       .::. .::..:.. :::...:::: ::.::::..: :.::.. ::: :.::::. :::::
XP_006 ACCDCRLGEVGSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHL
       90       100       110       120       130       140        

              120       130       140       150       160     
pF1KB3 KCFTCSTCRNRLVPGDRFHYINGSLFCEHDRPTALINGHLNSLQSNPLLPDQKVC
        ::.:. : .:.  ::.:   :. ..:. :   . .:: ..:             
XP_006 DCFACQLCNQRFCVGDKFFLKNNMILCQMDYEEGQLNGTFESQVQ          
      150       160       170       180       190             

>>NP_001230538 (OMIM: 180386) LIM domain only protein 3   (145 aa)
 initn: 546 init1: 508 opt: 539  Z-score: 550.4  bits: 108.0 E(85289): 6.4e-24
Smith-Waterman score: 539; 53.2% identity (78.6% similar) in 126 aa overlap (21-146:11-136)

               10        20        30        40        50        60
pF1KB3 MVNPGSSSQPPPVTAGSLSWKRCAGCGGKIADRFLLYAMDSYWHSRCLKCSCCQAQLGDI
                           : ::::. :: ::.:: :.:.:::  ::::.::. .::..
NP_001           MLSVQPDTKPKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEV
                         10        20        30        40        50

               70        80        90       100       110       120
pF1KB3 GTSCYTKSGMILCRNDYIRLFGNSGACSACGQSIPASELVMRAQGNVYHLKCFTCSTCRN
       :.. :::...:::: ::.:::: .: :.::.. ::: :.::::. ::::: ::.:. : .
NP_001 GSTLYTKANLILCRRDYLRLFGVTGNCAACSKLIPAFEMVMRAKDNVYHLDCFACQLCNQ
               60        70        80        90       100       110

              130       140       150       160     
pF1KB3 RLVPGDRFHYINGSLFCEHDRPTALINGHLNSLQSNPLLPDQKVC
       :.  ::.:   :. ..:. :   .:.                   
NP_001 RFCVGDKFFLKNNMILCQTDYEEGLMKEGYAPQVR          
              120       130       140               

>>XP_006719173 (OMIM: 180386) PREDICTED: LIM domain only  (145 aa)
 initn: 546 init1: 508 opt: 539  Z-score: 550.4  bits: 108.0 E(85289): 6.4e-24
Smith-Waterman score: 539; 53.2% identity (78.6% similar) in 126 aa overlap (21-146:11-136)

               10        20        30        40        50        60
pF1KB3 MVNPGSSSQPPPVTAGSLSWKRCAGCGGKIADRFLLYAMDSYWHSRCLKCSCCQAQLGDI
                           : ::::. :: ::.:: :.:.:::  ::::.::. .::..
XP_006           MLSVQPDTKPKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEV
                         10        20        30        40        50

               70        80        90       100       110       120
pF1KB3 GTSCYTKSGMILCRNDYIRLFGNSGACSACGQSIPASELVMRAQGNVYHLKCFTCSTCRN
       :.. :::...:::: ::.:::: .: :.::.. ::: :.::::. ::::: ::.:. : .
XP_006 GSTLYTKANLILCRRDYLRLFGVTGNCAACSKLIPAFEMVMRAKDNVYHLDCFACQLCNQ
               60        70        80        90       100       110

              130       140       150       160     
pF1KB3 RLVPGDRFHYINGSLFCEHDRPTALINGHLNSLQSNPLLPDQKVC
       :.  ::.:   :. ..:. :   .:.                   
XP_006 RFCVGDKFFLKNNMILCQTDYEEGLMKEGYAPQVR          
              120       130       140               

>>XP_011519065 (OMIM: 180386) PREDICTED: LIM domain only  (145 aa)
 initn: 546 init1: 508 opt: 539  Z-score: 550.4  bits: 108.0 E(85289): 6.4e-24
Smith-Waterman score: 539; 53.2% identity (78.6% similar) in 126 aa overlap (21-146:11-136)

               10        20        30        40        50        60
pF1KB3 MVNPGSSSQPPPVTAGSLSWKRCAGCGGKIADRFLLYAMDSYWHSRCLKCSCCQAQLGDI
                           : ::::. :: ::.:: :.:.:::  ::::.::. .::..
XP_011           MLSVQPDTKPKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEV
                         10        20        30        40        50

               70        80        90       100       110       120
pF1KB3 GTSCYTKSGMILCRNDYIRLFGNSGACSACGQSIPASELVMRAQGNVYHLKCFTCSTCRN
       :.. :::...:::: ::.:::: .: :.::.. ::: :.::::. ::::: ::.:. : .
XP_011 GSTLYTKANLILCRRDYLRLFGVTGNCAACSKLIPAFEMVMRAKDNVYHLDCFACQLCNQ
               60        70        80        90       100       110

              130       140       150       160     
pF1KB3 RLVPGDRFHYINGSLFCEHDRPTALINGHLNSLQSNPLLPDQKVC
       :.  ::.:   :. ..:. :   .:.                   
XP_011 RFCVGDKFFLKNNMILCQTDYEEGLMKEGYAPQVR          
              120       130       140               




165 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 12:27:23 2016 done: Thu Nov  3 12:27:24 2016
 Total Scan time:  5.240 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]
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