Result of FASTA (omim) for pF1KB3104
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB3104, 803 aa
  1>>>pF1KB3104 803 - 803 aa - 803 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.0303+/-0.000419; mu= 22.0006+/- 0.026
 mean_var=67.4325+/-13.776, 0's: 0 Z-trim(110.6): 80  B-trim: 488 in 1/52
 Lambda= 0.156185
 statistics sampled from 18910 (18992) to 18910 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.581), E-opt: 0.2 (0.223), width:  16
 Scan time:  8.150

The best scores are:                                      opt bits E(85289)
NP_001927 (OMIM: 126141,612956,616311) dipeptidyl  ( 803) 5350 1215.3       0
NP_570629 (OMIM: 126141,612956,616311) dipeptidyl  ( 865) 5243 1191.2       0
NP_001034439 (OMIM: 126141,612956,616311) dipeptid ( 801) 5236 1189.6       0
XP_016867299 (OMIM: 126141,612956,616311) PREDICTE ( 804) 5235 1189.3       0
XP_016867297 (OMIM: 126141,612956,616311) PREDICTE ( 804) 5235 1189.3       0
XP_016867300 (OMIM: 126141,612956,616311) PREDICTE ( 804) 5235 1189.3       0
XP_016867298 (OMIM: 126141,612956,616311) PREDICTE ( 804) 5235 1189.3       0
XP_016867301 (OMIM: 126141,612956,616311) PREDICTE ( 657) 4414 1004.3       0
NP_001277181 (OMIM: 126141,612956,616311) dipeptid ( 758) 4092 931.8       0
NP_001171505 (OMIM: 608209) inactive dipeptidyl pe ( 800) 2902 663.7 9.1e-190
NP_001171508 (OMIM: 608209) inactive dipeptidyl pe ( 792) 2880 658.7 2.8e-188
NP_001004360 (OMIM: 608209) inactive dipeptidyl pe ( 789) 2873 657.1 8.3e-188
NP_001308835 (OMIM: 608209) inactive dipeptidyl pe ( 789) 2873 657.1 8.3e-188
NP_065919 (OMIM: 608209) inactive dipeptidyl pepti ( 796) 2871 656.7 1.1e-187
NP_001308834 (OMIM: 608209) inactive dipeptidyl pe ( 813) 2869 656.2 1.6e-187
NP_001171507 (OMIM: 608209) inactive dipeptidyl pe ( 746) 2709 620.1 1.1e-176
NP_001308839 (OMIM: 608209) inactive dipeptidyl pe ( 746) 2709 620.1 1.1e-176
NP_001308840 (OMIM: 608209) inactive dipeptidyl pe ( 746) 2709 620.1 1.1e-176
XP_016860055 (OMIM: 608209) PREDICTED: inactive di ( 755) 2681 613.8 8.5e-175
NP_001308837 (OMIM: 608209) inactive dipeptidyl pe ( 766) 2680 613.6  1e-174
NP_001308838 (OMIM: 608209) inactive dipeptidyl pe ( 757) 2563 587.3 8.6e-167
NP_001308841 (OMIM: 608209) inactive dipeptidyl pe ( 681) 2491 571.0  6e-162
NP_001308843 (OMIM: 608209) inactive dipeptidyl pe ( 542) 1971 453.8 9.4e-127
NP_001308842 (OMIM: 608209) inactive dipeptidyl pe ( 542) 1971 453.8 9.4e-127
XP_005246428 (OMIM: 102720) PREDICTED: dipeptidyl  ( 765) 1542 357.2 1.6e-97
NP_004451 (OMIM: 600403) prolyl endopeptidase FAP  ( 760) 1536 355.8 3.9e-97
NP_001926 (OMIM: 102720) dipeptidyl peptidase 4 [H ( 766) 1535 355.6 4.6e-97
XP_011509098 (OMIM: 600403) PREDICTED: prolyl endo ( 750) 1511 350.2 1.9e-95
XP_016860054 (OMIM: 608209) PREDICTED: inactive di ( 776) 1399 325.0 7.9e-88
NP_001308836 (OMIM: 608209) inactive dipeptidyl pe ( 783) 1396 324.3 1.3e-87
NP_001278736 (OMIM: 600403) prolyl endopeptidase F ( 735) 1384 321.6 7.9e-87
XP_011509099 (OMIM: 600403) PREDICTED: prolyl endo ( 491)  840 198.9 4.5e-50
NP_001277182 (OMIM: 126141,612956,616311) dipeptid ( 353)  832 197.0 1.2e-49
XP_016859074 (OMIM: 600403) PREDICTED: prolyl endo ( 475)  782 185.8 3.8e-46
XP_011526712 (OMIM: 608258) PREDICTED: dipeptidyl  ( 863)  475 116.8 4.1e-25
XP_005259730 (OMIM: 608258) PREDICTED: dipeptidyl  ( 892)  475 116.8 4.2e-25
NP_631898 (OMIM: 608258) dipeptidyl peptidase 9 [H ( 892)  475 116.8 4.2e-25
XP_011526710 (OMIM: 608258) PREDICTED: dipeptidyl  ( 892)  475 116.8 4.2e-25
XP_011526707 (OMIM: 608258) PREDICTED: dipeptidyl  ( 946)  475 116.8 4.4e-25
XP_016882943 (OMIM: 608258) PREDICTED: dipeptidyl  ( 946)  475 116.8 4.4e-25
XP_011526708 (OMIM: 608258) PREDICTED: dipeptidyl  ( 946)  475 116.8 4.4e-25
XP_016882942 (OMIM: 608258) PREDICTED: dipeptidyl  ( 946)  475 116.8 4.4e-25
XP_005254562 (OMIM: 606819) PREDICTED: dipeptidyl  ( 479)  470 115.5 5.6e-25
XP_016877871 (OMIM: 606819) PREDICTED: dipeptidyl  ( 514)  470 115.5 5.9e-25
XP_016877872 (OMIM: 606819) PREDICTED: dipeptidyl  ( 514)  470 115.5 5.9e-25
XP_016877866 (OMIM: 606819) PREDICTED: dipeptidyl  ( 781)  470 115.7 8.2e-25
XP_011520035 (OMIM: 606819) PREDICTED: dipeptidyl  ( 824)  470 115.7 8.5e-25
XP_016877864 (OMIM: 606819) PREDICTED: dipeptidyl  ( 839)  470 115.7 8.6e-25
XP_011520033 (OMIM: 606819) PREDICTED: dipeptidyl  ( 840)  470 115.7 8.7e-25
XP_011520032 (OMIM: 606819) PREDICTED: dipeptidyl  ( 855)  470 115.7 8.8e-25


>>NP_001927 (OMIM: 126141,612956,616311) dipeptidyl amin  (803 aa)
 initn: 5350 init1: 5350 opt: 5350  Z-score: 6509.0  bits: 1215.3 E(85289):    0
Smith-Waterman score: 5350; 99.9% identity (99.9% similar) in 803 aa overlap (1-803:1-803)

               10        20        30        40        50        60
pF1KB3 MTTAKEPSASGKSVQQQEQELVGSNPPQRNWKGIAIALLVILVICSLIVTSVILLTPAED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTTAKEPSASGKSVQQQEQELVGSNPPQRNWKGIAIALLVILVICSLIVTSVILLTPAED
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 NSLSQKKKVTVEDLFSEDFKIHDPEAKWISDTEFIYREQKGTVRLWNVETNTSTVLIEGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NSLSQKKKVTVEDLFSEDFKIHDPEAKWISDTEFIYREQKGTVRLWNVETNTSTVLIEGK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 KIESLRAIRYEISPDREYALFSYNVEPIYQHSYTGYYVLSKIPHGDPQSLDPPEVSNAKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KIESLRAIRYEISPDREYALFSYNVEPIYQHSYTGYYVLSKIPHGDPQSLDPPEVSNAKL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 QYAGWGPKGQQLIFIFENNIYYCAHVGKQAIRVVSTGKEGVIYNGLSDWLYEEEILKTHI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QYAGWGPKGQQLIFIFENNIYYCAHVGKQAIRVVSTGKEGVIYNGLSDWLYEEEILKTHI
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 AHWWSPDGTRLAYAAINDSRVPIMELPTYTGSIYPTVKPYHYPKAGSENPSISLHVIGLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AHWWSPDGTRLAYAAINDSRVPIMELPTYTGSIYPTVKPYHYPKAGSENPSISLHVIGLN
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 GPTHDLEMMPPDDPRMREYYITMVKWATSTKVAVTWLNRAQNVSILTLCDATTGVCTKKH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPTHDLEMMPPDDPRMREYYITMVKWATSTKVAVTWLNRAQNVSILTLCDATTGVCTKKH
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 EDESEAWLHRQNEEPVFSKDGRKFFFIRAIPQGGRGKFYHITVSSSQPNSSNDNIQSITS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDESEAWLHRQNEEPVFSKDGRKFFFIRAIPQGGRGKFYHITVSSSQPNSSNDNIQSITS
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 GDWDVTKILAYDEKGNKIYFLSTEDLPRRRQLYSANTVGNFNRQCLSCDLVENCTYFSAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GDWDVTKILAYDEKGNKIYFLSTEDLPRRRQLYSANTVGNFNRQCLSCDLVENCTYFSAS
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB3 FSHSMDFFLLKCEGPGVPMVTVHNTTDKKKMFDLETNEHVKKAINDRQMPKVEYRDIEID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FSHSMDFFLLKCEGPGVPMVTVHNTTDKKKMFDLETNEHVKKAINDRQMPKVEYRDIEID
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB3 DYNLPMQILKPATFTDTTHYPLLLVVDGTPGSQSVAEKFEVSWETVMVSSHGAVVVKCDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DYNLPMQILKPATFTDTTHYPLLLVVDGTPGSQSVAEKFEVSWETVMVSSHGAVVVKCDG
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB3 RGSGFQGTKLLHEVRRRLGLLEEKDQMEAVRTMLKEQYIDRTRVAVFGKDYGGYLSTYIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGSGFQGTKLLHEVRRRLGLLEEKDQMEAVRTMLKEQYIDRTRVAVFGKDYGGYLSTYIL
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB3 PAKGENQGQTFTCGSALSPITDFKLYASAFSERYLGLHGLDNRAYEMTKVAHRVSALEEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PAKGENQGQTFTCGSALSPITDFKLYASAFSERYLGLHGLDNRAYEMTKVAHRVSALEEQ
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB3 QFLIIHPTADEKIHFQHTAELITQLIRGKANYSLQIYPDESHYFTSSSLKQHLYRSIINF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QFLIIHPTADEKIHFQHTAELITQLIRGKANYSLQIYPDESHYFTSSSLKQHLYRSIINF
              730       740       750       760       770       780

              790       800   
pF1KB3 FVECFRIQDKLPTVTAKEDEEED
       ::::::::::: :::::::::::
NP_001 FVECFRIQDKLLTVTAKEDEEED
              790       800   

>>NP_570629 (OMIM: 126141,612956,616311) dipeptidyl amin  (865 aa)
 initn: 5241 init1: 5241 opt: 5243  Z-score: 6378.3  bits: 1191.2 E(85289):    0
Smith-Waterman score: 5243; 99.1% identity (99.6% similar) in 792 aa overlap (12-803:74-865)

                                  10        20        30        40 
pF1KB3                    MTTAKEPSASGKSVQQQEQELVGSNPPQRNWKGIAIALLVI
                                     .:  ..:.::::::::::::::::::::::
NP_570 LGPRAQAAAPRERGGGGGGAGGRPRFQYQARSDGDEEDELVGSNPPQRNWKGIAIALLVI
            50        60        70        80        90       100   

              50        60        70        80        90       100 
pF1KB3 LVICSLIVTSVILLTPAEDNSLSQKKKVTVEDLFSEDFKIHDPEAKWISDTEFIYREQKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 LVICSLIVTSVILLTPAEDNSLSQKKKVTVEDLFSEDFKIHDPEAKWISDTEFIYREQKG
           110       120       130       140       150       160   

             110       120       130       140       150       160 
pF1KB3 TVRLWNVETNTSTVLIEGKKIESLRAIRYEISPDREYALFSYNVEPIYQHSYTGYYVLSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 TVRLWNVETNTSTVLIEGKKIESLRAIRYEISPDREYALFSYNVEPIYQHSYTGYYVLSK
           170       180       190       200       210       220   

             170       180       190       200       210       220 
pF1KB3 IPHGDPQSLDPPEVSNAKLQYAGWGPKGQQLIFIFENNIYYCAHVGKQAIRVVSTGKEGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 IPHGDPQSLDPPEVSNAKLQYAGWGPKGQQLIFIFENNIYYCAHVGKQAIRVVSTGKEGV
           230       240       250       260       270       280   

             230       240       250       260       270       280 
pF1KB3 IYNGLSDWLYEEEILKTHIAHWWSPDGTRLAYAAINDSRVPIMELPTYTGSIYPTVKPYH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 IYNGLSDWLYEEEILKTHIAHWWSPDGTRLAYAAINDSRVPIMELPTYTGSIYPTVKPYH
           290       300       310       320       330       340   

             290       300       310       320       330       340 
pF1KB3 YPKAGSENPSISLHVIGLNGPTHDLEMMPPDDPRMREYYITMVKWATSTKVAVTWLNRAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 YPKAGSENPSISLHVIGLNGPTHDLEMMPPDDPRMREYYITMVKWATSTKVAVTWLNRAQ
           350       360       370       380       390       400   

             350       360       370       380       390       400 
pF1KB3 NVSILTLCDATTGVCTKKHEDESEAWLHRQNEEPVFSKDGRKFFFIRAIPQGGRGKFYHI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 NVSILTLCDATTGVCTKKHEDESEAWLHRQNEEPVFSKDGRKFFFIRAIPQGGRGKFYHI
           410       420       430       440       450       460   

             410       420       430       440       450       460 
pF1KB3 TVSSSQPNSSNDNIQSITSGDWDVTKILAYDEKGNKIYFLSTEDLPRRRQLYSANTVGNF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 TVSSSQPNSSNDNIQSITSGDWDVTKILAYDEKGNKIYFLSTEDLPRRRQLYSANTVGNF
           470       480       490       500       510       520   

             470       480       490       500       510       520 
pF1KB3 NRQCLSCDLVENCTYFSASFSHSMDFFLLKCEGPGVPMVTVHNTTDKKKMFDLETNEHVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 NRQCLSCDLVENCTYFSASFSHSMDFFLLKCEGPGVPMVTVHNTTDKKKMFDLETNEHVK
           530       540       550       560       570       580   

             530       540       550       560       570       580 
pF1KB3 KAINDRQMPKVEYRDIEIDDYNLPMQILKPATFTDTTHYPLLLVVDGTPGSQSVAEKFEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 KAINDRQMPKVEYRDIEIDDYNLPMQILKPATFTDTTHYPLLLVVDGTPGSQSVAEKFEV
           590       600       610       620       630       640   

             590       600       610       620       630       640 
pF1KB3 SWETVMVSSHGAVVVKCDGRGSGFQGTKLLHEVRRRLGLLEEKDQMEAVRTMLKEQYIDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 SWETVMVSSHGAVVVKCDGRGSGFQGTKLLHEVRRRLGLLEEKDQMEAVRTMLKEQYIDR
           650       660       670       680       690       700   

             650       660       670       680       690       700 
pF1KB3 TRVAVFGKDYGGYLSTYILPAKGENQGQTFTCGSALSPITDFKLYASAFSERYLGLHGLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 TRVAVFGKDYGGYLSTYILPAKGENQGQTFTCGSALSPITDFKLYASAFSERYLGLHGLD
           710       720       730       740       750       760   

             710       720       730       740       750       760 
pF1KB3 NRAYEMTKVAHRVSALEEQQFLIIHPTADEKIHFQHTAELITQLIRGKANYSLQIYPDES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 NRAYEMTKVAHRVSALEEQQFLIIHPTADEKIHFQHTAELITQLIRGKANYSLQIYPDES
           770       780       790       800       810       820   

             770       780       790       800   
pF1KB3 HYFTSSSLKQHLYRSIINFFVECFRIQDKLPTVTAKEDEEED
       :::::::::::::::::::::::::::::: :::::::::::
NP_570 HYFTSSSLKQHLYRSIINFFVECFRIQDKLLTVTAKEDEEED
           830       840       850       860     

>>NP_001034439 (OMIM: 126141,612956,616311) dipeptidyl a  (801 aa)
 initn: 5233 init1: 5233 opt: 5236  Z-score: 6370.2  bits: 1189.6 E(85289):    0
Smith-Waterman score: 5236; 99.2% identity (99.6% similar) in 790 aa overlap (14-803:12-801)

               10        20        30        40        50        60
pF1KB3 MTTAKEPSASGKSVQQQEQELVGSNPPQRNWKGIAIALLVILVICSLIVTSVILLTPAED
                    .: . .:::::::::::::::::::::::::::::::::::::::::
NP_001   MKEKAMIKTAKMQGNVMELVGSNPPQRNWKGIAIALLVILVICSLIVTSVILLTPAED
                 10        20        30        40        50        

               70        80        90       100       110       120
pF1KB3 NSLSQKKKVTVEDLFSEDFKIHDPEAKWISDTEFIYREQKGTVRLWNVETNTSTVLIEGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NSLSQKKKVTVEDLFSEDFKIHDPEAKWISDTEFIYREQKGTVRLWNVETNTSTVLIEGK
       60        70        80        90       100       110        

              130       140       150       160       170       180
pF1KB3 KIESLRAIRYEISPDREYALFSYNVEPIYQHSYTGYYVLSKIPHGDPQSLDPPEVSNAKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KIESLRAIRYEISPDREYALFSYNVEPIYQHSYTGYYVLSKIPHGDPQSLDPPEVSNAKL
      120       130       140       150       160       170        

              190       200       210       220       230       240
pF1KB3 QYAGWGPKGQQLIFIFENNIYYCAHVGKQAIRVVSTGKEGVIYNGLSDWLYEEEILKTHI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QYAGWGPKGQQLIFIFENNIYYCAHVGKQAIRVVSTGKEGVIYNGLSDWLYEEEILKTHI
      180       190       200       210       220       230        

              250       260       270       280       290       300
pF1KB3 AHWWSPDGTRLAYAAINDSRVPIMELPTYTGSIYPTVKPYHYPKAGSENPSISLHVIGLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AHWWSPDGTRLAYAAINDSRVPIMELPTYTGSIYPTVKPYHYPKAGSENPSISLHVIGLN
      240       250       260       270       280       290        

              310       320       330       340       350       360
pF1KB3 GPTHDLEMMPPDDPRMREYYITMVKWATSTKVAVTWLNRAQNVSILTLCDATTGVCTKKH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPTHDLEMMPPDDPRMREYYITMVKWATSTKVAVTWLNRAQNVSILTLCDATTGVCTKKH
      300       310       320       330       340       350        

              370       380       390       400       410       420
pF1KB3 EDESEAWLHRQNEEPVFSKDGRKFFFIRAIPQGGRGKFYHITVSSSQPNSSNDNIQSITS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDESEAWLHRQNEEPVFSKDGRKFFFIRAIPQGGRGKFYHITVSSSQPNSSNDNIQSITS
      360       370       380       390       400       410        

              430       440       450       460       470       480
pF1KB3 GDWDVTKILAYDEKGNKIYFLSTEDLPRRRQLYSANTVGNFNRQCLSCDLVENCTYFSAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GDWDVTKILAYDEKGNKIYFLSTEDLPRRRQLYSANTVGNFNRQCLSCDLVENCTYFSAS
      420       430       440       450       460       470        

              490       500       510       520       530       540
pF1KB3 FSHSMDFFLLKCEGPGVPMVTVHNTTDKKKMFDLETNEHVKKAINDRQMPKVEYRDIEID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FSHSMDFFLLKCEGPGVPMVTVHNTTDKKKMFDLETNEHVKKAINDRQMPKVEYRDIEID
      480       490       500       510       520       530        

              550       560       570       580       590       600
pF1KB3 DYNLPMQILKPATFTDTTHYPLLLVVDGTPGSQSVAEKFEVSWETVMVSSHGAVVVKCDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DYNLPMQILKPATFTDTTHYPLLLVVDGTPGSQSVAEKFEVSWETVMVSSHGAVVVKCDG
      540       550       560       570       580       590        

              610       620       630       640       650       660
pF1KB3 RGSGFQGTKLLHEVRRRLGLLEEKDQMEAVRTMLKEQYIDRTRVAVFGKDYGGYLSTYIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGSGFQGTKLLHEVRRRLGLLEEKDQMEAVRTMLKEQYIDRTRVAVFGKDYGGYLSTYIL
      600       610       620       630       640       650        

              670       680       690       700       710       720
pF1KB3 PAKGENQGQTFTCGSALSPITDFKLYASAFSERYLGLHGLDNRAYEMTKVAHRVSALEEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PAKGENQGQTFTCGSALSPITDFKLYASAFSERYLGLHGLDNRAYEMTKVAHRVSALEEQ
      660       670       680       690       700       710        

              730       740       750       760       770       780
pF1KB3 QFLIIHPTADEKIHFQHTAELITQLIRGKANYSLQIYPDESHYFTSSSLKQHLYRSIINF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QFLIIHPTADEKIHFQHTAELITQLIRGKANYSLQIYPDESHYFTSSSLKQHLYRSIINF
      720       730       740       750       760       770        

              790       800   
pF1KB3 FVECFRIQDKLPTVTAKEDEEED
       ::::::::::: :::::::::::
NP_001 FVECFRIQDKLLTVTAKEDEEED
      780       790       800 

>>XP_016867299 (OMIM: 126141,612956,616311) PREDICTED: d  (804 aa)
 initn: 5235 init1: 5235 opt: 5235  Z-score: 6369.0  bits: 1189.3 E(85289):    0
Smith-Waterman score: 5235; 99.7% identity (99.9% similar) in 785 aa overlap (19-803:20-804)

                10        20        30        40        50         
pF1KB3  MTTAKEPSASGKSVQQQEQELVGSNPPQRNWKGIAIALLVILVICSLIVTSVILLTPAE
                          .::::::::::::::::::::::::::::::::::::::::
XP_016 MNQTAGVSNSVRCPPGKGHKELVGSNPPQRNWKGIAIALLVILVICSLIVTSVILLTPAE
               10        20        30        40        50        60

      60        70        80        90       100       110         
pF1KB3 DNSLSQKKKVTVEDLFSEDFKIHDPEAKWISDTEFIYREQKGTVRLWNVETNTSTVLIEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DNSLSQKKKVTVEDLFSEDFKIHDPEAKWISDTEFIYREQKGTVRLWNVETNTSTVLIEG
               70        80        90       100       110       120

     120       130       140       150       160       170         
pF1KB3 KKIESLRAIRYEISPDREYALFSYNVEPIYQHSYTGYYVLSKIPHGDPQSLDPPEVSNAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKIESLRAIRYEISPDREYALFSYNVEPIYQHSYTGYYVLSKIPHGDPQSLDPPEVSNAK
              130       140       150       160       170       180

     180       190       200       210       220       230         
pF1KB3 LQYAGWGPKGQQLIFIFENNIYYCAHVGKQAIRVVSTGKEGVIYNGLSDWLYEEEILKTH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQYAGWGPKGQQLIFIFENNIYYCAHVGKQAIRVVSTGKEGVIYNGLSDWLYEEEILKTH
              190       200       210       220       230       240

     240       250       260       270       280       290         
pF1KB3 IAHWWSPDGTRLAYAAINDSRVPIMELPTYTGSIYPTVKPYHYPKAGSENPSISLHVIGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IAHWWSPDGTRLAYAAINDSRVPIMELPTYTGSIYPTVKPYHYPKAGSENPSISLHVIGL
              250       260       270       280       290       300

     300       310       320       330       340       350         
pF1KB3 NGPTHDLEMMPPDDPRMREYYITMVKWATSTKVAVTWLNRAQNVSILTLCDATTGVCTKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGPTHDLEMMPPDDPRMREYYITMVKWATSTKVAVTWLNRAQNVSILTLCDATTGVCTKK
              310       320       330       340       350       360

     360       370       380       390       400       410         
pF1KB3 HEDESEAWLHRQNEEPVFSKDGRKFFFIRAIPQGGRGKFYHITVSSSQPNSSNDNIQSIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HEDESEAWLHRQNEEPVFSKDGRKFFFIRAIPQGGRGKFYHITVSSSQPNSSNDNIQSIT
              370       380       390       400       410       420

     420       430       440       450       460       470         
pF1KB3 SGDWDVTKILAYDEKGNKIYFLSTEDLPRRRQLYSANTVGNFNRQCLSCDLVENCTYFSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGDWDVTKILAYDEKGNKIYFLSTEDLPRRRQLYSANTVGNFNRQCLSCDLVENCTYFSA
              430       440       450       460       470       480

     480       490       500       510       520       530         
pF1KB3 SFSHSMDFFLLKCEGPGVPMVTVHNTTDKKKMFDLETNEHVKKAINDRQMPKVEYRDIEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFSHSMDFFLLKCEGPGVPMVTVHNTTDKKKMFDLETNEHVKKAINDRQMPKVEYRDIEI
              490       500       510       520       530       540

     540       550       560       570       580       590         
pF1KB3 DDYNLPMQILKPATFTDTTHYPLLLVVDGTPGSQSVAEKFEVSWETVMVSSHGAVVVKCD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDYNLPMQILKPATFTDTTHYPLLLVVDGTPGSQSVAEKFEVSWETVMVSSHGAVVVKCD
              550       560       570       580       590       600

     600       610       620       630       640       650         
pF1KB3 GRGSGFQGTKLLHEVRRRLGLLEEKDQMEAVRTMLKEQYIDRTRVAVFGKDYGGYLSTYI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRGSGFQGTKLLHEVRRRLGLLEEKDQMEAVRTMLKEQYIDRTRVAVFGKDYGGYLSTYI
              610       620       630       640       650       660

     660       670       680       690       700       710         
pF1KB3 LPAKGENQGQTFTCGSALSPITDFKLYASAFSERYLGLHGLDNRAYEMTKVAHRVSALEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPAKGENQGQTFTCGSALSPITDFKLYASAFSERYLGLHGLDNRAYEMTKVAHRVSALEE
              670       680       690       700       710       720

     720       730       740       750       760       770         
pF1KB3 QQFLIIHPTADEKIHFQHTAELITQLIRGKANYSLQIYPDESHYFTSSSLKQHLYRSIIN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQFLIIHPTADEKIHFQHTAELITQLIRGKANYSLQIYPDESHYFTSSSLKQHLYRSIIN
              730       740       750       760       770       780

     780       790       800   
pF1KB3 FFVECFRIQDKLPTVTAKEDEEED
       :::::::::::: :::::::::::
XP_016 FFVECFRIQDKLLTVTAKEDEEED
              790       800    

>>XP_016867297 (OMIM: 126141,612956,616311) PREDICTED: d  (804 aa)
 initn: 5235 init1: 5235 opt: 5235  Z-score: 6369.0  bits: 1189.3 E(85289):    0
Smith-Waterman score: 5235; 99.7% identity (99.9% similar) in 785 aa overlap (19-803:20-804)

                10        20        30        40        50         
pF1KB3  MTTAKEPSASGKSVQQQEQELVGSNPPQRNWKGIAIALLVILVICSLIVTSVILLTPAE
                          .::::::::::::::::::::::::::::::::::::::::
XP_016 MNQTAGVSNSVRCPPGKGHKELVGSNPPQRNWKGIAIALLVILVICSLIVTSVILLTPAE
               10        20        30        40        50        60

      60        70        80        90       100       110         
pF1KB3 DNSLSQKKKVTVEDLFSEDFKIHDPEAKWISDTEFIYREQKGTVRLWNVETNTSTVLIEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DNSLSQKKKVTVEDLFSEDFKIHDPEAKWISDTEFIYREQKGTVRLWNVETNTSTVLIEG
               70        80        90       100       110       120

     120       130       140       150       160       170         
pF1KB3 KKIESLRAIRYEISPDREYALFSYNVEPIYQHSYTGYYVLSKIPHGDPQSLDPPEVSNAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKIESLRAIRYEISPDREYALFSYNVEPIYQHSYTGYYVLSKIPHGDPQSLDPPEVSNAK
              130       140       150       160       170       180

     180       190       200       210       220       230         
pF1KB3 LQYAGWGPKGQQLIFIFENNIYYCAHVGKQAIRVVSTGKEGVIYNGLSDWLYEEEILKTH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQYAGWGPKGQQLIFIFENNIYYCAHVGKQAIRVVSTGKEGVIYNGLSDWLYEEEILKTH
              190       200       210       220       230       240

     240       250       260       270       280       290         
pF1KB3 IAHWWSPDGTRLAYAAINDSRVPIMELPTYTGSIYPTVKPYHYPKAGSENPSISLHVIGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IAHWWSPDGTRLAYAAINDSRVPIMELPTYTGSIYPTVKPYHYPKAGSENPSISLHVIGL
              250       260       270       280       290       300

     300       310       320       330       340       350         
pF1KB3 NGPTHDLEMMPPDDPRMREYYITMVKWATSTKVAVTWLNRAQNVSILTLCDATTGVCTKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGPTHDLEMMPPDDPRMREYYITMVKWATSTKVAVTWLNRAQNVSILTLCDATTGVCTKK
              310       320       330       340       350       360

     360       370       380       390       400       410         
pF1KB3 HEDESEAWLHRQNEEPVFSKDGRKFFFIRAIPQGGRGKFYHITVSSSQPNSSNDNIQSIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HEDESEAWLHRQNEEPVFSKDGRKFFFIRAIPQGGRGKFYHITVSSSQPNSSNDNIQSIT
              370       380       390       400       410       420

     420       430       440       450       460       470         
pF1KB3 SGDWDVTKILAYDEKGNKIYFLSTEDLPRRRQLYSANTVGNFNRQCLSCDLVENCTYFSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGDWDVTKILAYDEKGNKIYFLSTEDLPRRRQLYSANTVGNFNRQCLSCDLVENCTYFSA
              430       440       450       460       470       480

     480       490       500       510       520       530         
pF1KB3 SFSHSMDFFLLKCEGPGVPMVTVHNTTDKKKMFDLETNEHVKKAINDRQMPKVEYRDIEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFSHSMDFFLLKCEGPGVPMVTVHNTTDKKKMFDLETNEHVKKAINDRQMPKVEYRDIEI
              490       500       510       520       530       540

     540       550       560       570       580       590         
pF1KB3 DDYNLPMQILKPATFTDTTHYPLLLVVDGTPGSQSVAEKFEVSWETVMVSSHGAVVVKCD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDYNLPMQILKPATFTDTTHYPLLLVVDGTPGSQSVAEKFEVSWETVMVSSHGAVVVKCD
              550       560       570       580       590       600

     600       610       620       630       640       650         
pF1KB3 GRGSGFQGTKLLHEVRRRLGLLEEKDQMEAVRTMLKEQYIDRTRVAVFGKDYGGYLSTYI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRGSGFQGTKLLHEVRRRLGLLEEKDQMEAVRTMLKEQYIDRTRVAVFGKDYGGYLSTYI
              610       620       630       640       650       660

     660       670       680       690       700       710         
pF1KB3 LPAKGENQGQTFTCGSALSPITDFKLYASAFSERYLGLHGLDNRAYEMTKVAHRVSALEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPAKGENQGQTFTCGSALSPITDFKLYASAFSERYLGLHGLDNRAYEMTKVAHRVSALEE
              670       680       690       700       710       720

     720       730       740       750       760       770         
pF1KB3 QQFLIIHPTADEKIHFQHTAELITQLIRGKANYSLQIYPDESHYFTSSSLKQHLYRSIIN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQFLIIHPTADEKIHFQHTAELITQLIRGKANYSLQIYPDESHYFTSSSLKQHLYRSIIN
              730       740       750       760       770       780

     780       790       800   
pF1KB3 FFVECFRIQDKLPTVTAKEDEEED
       :::::::::::: :::::::::::
XP_016 FFVECFRIQDKLLTVTAKEDEEED
              790       800    

>>XP_016867300 (OMIM: 126141,612956,616311) PREDICTED: d  (804 aa)
 initn: 5235 init1: 5235 opt: 5235  Z-score: 6369.0  bits: 1189.3 E(85289):    0
Smith-Waterman score: 5235; 99.7% identity (99.9% similar) in 785 aa overlap (19-803:20-804)

                10        20        30        40        50         
pF1KB3  MTTAKEPSASGKSVQQQEQELVGSNPPQRNWKGIAIALLVILVICSLIVTSVILLTPAE
                          .::::::::::::::::::::::::::::::::::::::::
XP_016 MNQTAGVSNSVRCPPGKGHKELVGSNPPQRNWKGIAIALLVILVICSLIVTSVILLTPAE
               10        20        30        40        50        60

      60        70        80        90       100       110         
pF1KB3 DNSLSQKKKVTVEDLFSEDFKIHDPEAKWISDTEFIYREQKGTVRLWNVETNTSTVLIEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DNSLSQKKKVTVEDLFSEDFKIHDPEAKWISDTEFIYREQKGTVRLWNVETNTSTVLIEG
               70        80        90       100       110       120

     120       130       140       150       160       170         
pF1KB3 KKIESLRAIRYEISPDREYALFSYNVEPIYQHSYTGYYVLSKIPHGDPQSLDPPEVSNAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKIESLRAIRYEISPDREYALFSYNVEPIYQHSYTGYYVLSKIPHGDPQSLDPPEVSNAK
              130       140       150       160       170       180

     180       190       200       210       220       230         
pF1KB3 LQYAGWGPKGQQLIFIFENNIYYCAHVGKQAIRVVSTGKEGVIYNGLSDWLYEEEILKTH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQYAGWGPKGQQLIFIFENNIYYCAHVGKQAIRVVSTGKEGVIYNGLSDWLYEEEILKTH
              190       200       210       220       230       240

     240       250       260       270       280       290         
pF1KB3 IAHWWSPDGTRLAYAAINDSRVPIMELPTYTGSIYPTVKPYHYPKAGSENPSISLHVIGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IAHWWSPDGTRLAYAAINDSRVPIMELPTYTGSIYPTVKPYHYPKAGSENPSISLHVIGL
              250       260       270       280       290       300

     300       310       320       330       340       350         
pF1KB3 NGPTHDLEMMPPDDPRMREYYITMVKWATSTKVAVTWLNRAQNVSILTLCDATTGVCTKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGPTHDLEMMPPDDPRMREYYITMVKWATSTKVAVTWLNRAQNVSILTLCDATTGVCTKK
              310       320       330       340       350       360

     360       370       380       390       400       410         
pF1KB3 HEDESEAWLHRQNEEPVFSKDGRKFFFIRAIPQGGRGKFYHITVSSSQPNSSNDNIQSIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HEDESEAWLHRQNEEPVFSKDGRKFFFIRAIPQGGRGKFYHITVSSSQPNSSNDNIQSIT
              370       380       390       400       410       420

     420       430       440       450       460       470         
pF1KB3 SGDWDVTKILAYDEKGNKIYFLSTEDLPRRRQLYSANTVGNFNRQCLSCDLVENCTYFSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGDWDVTKILAYDEKGNKIYFLSTEDLPRRRQLYSANTVGNFNRQCLSCDLVENCTYFSA
              430       440       450       460       470       480

     480       490       500       510       520       530         
pF1KB3 SFSHSMDFFLLKCEGPGVPMVTVHNTTDKKKMFDLETNEHVKKAINDRQMPKVEYRDIEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFSHSMDFFLLKCEGPGVPMVTVHNTTDKKKMFDLETNEHVKKAINDRQMPKVEYRDIEI
              490       500       510       520       530       540

     540       550       560       570       580       590         
pF1KB3 DDYNLPMQILKPATFTDTTHYPLLLVVDGTPGSQSVAEKFEVSWETVMVSSHGAVVVKCD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDYNLPMQILKPATFTDTTHYPLLLVVDGTPGSQSVAEKFEVSWETVMVSSHGAVVVKCD
              550       560       570       580       590       600

     600       610       620       630       640       650         
pF1KB3 GRGSGFQGTKLLHEVRRRLGLLEEKDQMEAVRTMLKEQYIDRTRVAVFGKDYGGYLSTYI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRGSGFQGTKLLHEVRRRLGLLEEKDQMEAVRTMLKEQYIDRTRVAVFGKDYGGYLSTYI
              610       620       630       640       650       660

     660       670       680       690       700       710         
pF1KB3 LPAKGENQGQTFTCGSALSPITDFKLYASAFSERYLGLHGLDNRAYEMTKVAHRVSALEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPAKGENQGQTFTCGSALSPITDFKLYASAFSERYLGLHGLDNRAYEMTKVAHRVSALEE
              670       680       690       700       710       720

     720       730       740       750       760       770         
pF1KB3 QQFLIIHPTADEKIHFQHTAELITQLIRGKANYSLQIYPDESHYFTSSSLKQHLYRSIIN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQFLIIHPTADEKIHFQHTAELITQLIRGKANYSLQIYPDESHYFTSSSLKQHLYRSIIN
              730       740       750       760       770       780

     780       790       800   
pF1KB3 FFVECFRIQDKLPTVTAKEDEEED
       :::::::::::: :::::::::::
XP_016 FFVECFRIQDKLLTVTAKEDEEED
              790       800    

>>XP_016867298 (OMIM: 126141,612956,616311) PREDICTED: d  (804 aa)
 initn: 5235 init1: 5235 opt: 5235  Z-score: 6369.0  bits: 1189.3 E(85289):    0
Smith-Waterman score: 5235; 99.7% identity (99.9% similar) in 785 aa overlap (19-803:20-804)

                10        20        30        40        50         
pF1KB3  MTTAKEPSASGKSVQQQEQELVGSNPPQRNWKGIAIALLVILVICSLIVTSVILLTPAE
                          .::::::::::::::::::::::::::::::::::::::::
XP_016 MNQTAGVSNSVRCPPGKGHKELVGSNPPQRNWKGIAIALLVILVICSLIVTSVILLTPAE
               10        20        30        40        50        60

      60        70        80        90       100       110         
pF1KB3 DNSLSQKKKVTVEDLFSEDFKIHDPEAKWISDTEFIYREQKGTVRLWNVETNTSTVLIEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DNSLSQKKKVTVEDLFSEDFKIHDPEAKWISDTEFIYREQKGTVRLWNVETNTSTVLIEG
               70        80        90       100       110       120

     120       130       140       150       160       170         
pF1KB3 KKIESLRAIRYEISPDREYALFSYNVEPIYQHSYTGYYVLSKIPHGDPQSLDPPEVSNAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKIESLRAIRYEISPDREYALFSYNVEPIYQHSYTGYYVLSKIPHGDPQSLDPPEVSNAK
              130       140       150       160       170       180

     180       190       200       210       220       230         
pF1KB3 LQYAGWGPKGQQLIFIFENNIYYCAHVGKQAIRVVSTGKEGVIYNGLSDWLYEEEILKTH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQYAGWGPKGQQLIFIFENNIYYCAHVGKQAIRVVSTGKEGVIYNGLSDWLYEEEILKTH
              190       200       210       220       230       240

     240       250       260       270       280       290         
pF1KB3 IAHWWSPDGTRLAYAAINDSRVPIMELPTYTGSIYPTVKPYHYPKAGSENPSISLHVIGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IAHWWSPDGTRLAYAAINDSRVPIMELPTYTGSIYPTVKPYHYPKAGSENPSISLHVIGL
              250       260       270       280       290       300

     300       310       320       330       340       350         
pF1KB3 NGPTHDLEMMPPDDPRMREYYITMVKWATSTKVAVTWLNRAQNVSILTLCDATTGVCTKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGPTHDLEMMPPDDPRMREYYITMVKWATSTKVAVTWLNRAQNVSILTLCDATTGVCTKK
              310       320       330       340       350       360

     360       370       380       390       400       410         
pF1KB3 HEDESEAWLHRQNEEPVFSKDGRKFFFIRAIPQGGRGKFYHITVSSSQPNSSNDNIQSIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HEDESEAWLHRQNEEPVFSKDGRKFFFIRAIPQGGRGKFYHITVSSSQPNSSNDNIQSIT
              370       380       390       400       410       420

     420       430       440       450       460       470         
pF1KB3 SGDWDVTKILAYDEKGNKIYFLSTEDLPRRRQLYSANTVGNFNRQCLSCDLVENCTYFSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGDWDVTKILAYDEKGNKIYFLSTEDLPRRRQLYSANTVGNFNRQCLSCDLVENCTYFSA
              430       440       450       460       470       480

     480       490       500       510       520       530         
pF1KB3 SFSHSMDFFLLKCEGPGVPMVTVHNTTDKKKMFDLETNEHVKKAINDRQMPKVEYRDIEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFSHSMDFFLLKCEGPGVPMVTVHNTTDKKKMFDLETNEHVKKAINDRQMPKVEYRDIEI
              490       500       510       520       530       540

     540       550       560       570       580       590         
pF1KB3 DDYNLPMQILKPATFTDTTHYPLLLVVDGTPGSQSVAEKFEVSWETVMVSSHGAVVVKCD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDYNLPMQILKPATFTDTTHYPLLLVVDGTPGSQSVAEKFEVSWETVMVSSHGAVVVKCD
              550       560       570       580       590       600

     600       610       620       630       640       650         
pF1KB3 GRGSGFQGTKLLHEVRRRLGLLEEKDQMEAVRTMLKEQYIDRTRVAVFGKDYGGYLSTYI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRGSGFQGTKLLHEVRRRLGLLEEKDQMEAVRTMLKEQYIDRTRVAVFGKDYGGYLSTYI
              610       620       630       640       650       660

     660       670       680       690       700       710         
pF1KB3 LPAKGENQGQTFTCGSALSPITDFKLYASAFSERYLGLHGLDNRAYEMTKVAHRVSALEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPAKGENQGQTFTCGSALSPITDFKLYASAFSERYLGLHGLDNRAYEMTKVAHRVSALEE
              670       680       690       700       710       720

     720       730       740       750       760       770         
pF1KB3 QQFLIIHPTADEKIHFQHTAELITQLIRGKANYSLQIYPDESHYFTSSSLKQHLYRSIIN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQFLIIHPTADEKIHFQHTAELITQLIRGKANYSLQIYPDESHYFTSSSLKQHLYRSIIN
              730       740       750       760       770       780

     780       790       800   
pF1KB3 FFVECFRIQDKLPTVTAKEDEEED
       :::::::::::: :::::::::::
XP_016 FFVECFRIQDKLLTVTAKEDEEED
              790       800    

>>XP_016867301 (OMIM: 126141,612956,616311) PREDICTED: d  (657 aa)
 initn: 4414 init1: 4414 opt: 4414  Z-score: 5370.4  bits: 1004.3 E(85289):    0
Smith-Waterman score: 4414; 99.8% identity (99.8% similar) in 656 aa overlap (148-803:2-657)

       120       130       140       150       160       170       
pF1KB3 EGKKIESLRAIRYEISPDREYALFSYNVEPIYQHSYTGYYVLSKIPHGDPQSLDPPEVSN
                                     ::::::::::::::::::::::::::::::
XP_016                              MIYQHSYTGYYVLSKIPHGDPQSLDPPEVSN
                                            10        20        30 

       180       190       200       210       220       230       
pF1KB3 AKLQYAGWGPKGQQLIFIFENNIYYCAHVGKQAIRVVSTGKEGVIYNGLSDWLYEEEILK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKLQYAGWGPKGQQLIFIFENNIYYCAHVGKQAIRVVSTGKEGVIYNGLSDWLYEEEILK
              40        50        60        70        80        90 

       240       250       260       270       280       290       
pF1KB3 THIAHWWSPDGTRLAYAAINDSRVPIMELPTYTGSIYPTVKPYHYPKAGSENPSISLHVI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 THIAHWWSPDGTRLAYAAINDSRVPIMELPTYTGSIYPTVKPYHYPKAGSENPSISLHVI
             100       110       120       130       140       150 

       300       310       320       330       340       350       
pF1KB3 GLNGPTHDLEMMPPDDPRMREYYITMVKWATSTKVAVTWLNRAQNVSILTLCDATTGVCT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLNGPTHDLEMMPPDDPRMREYYITMVKWATSTKVAVTWLNRAQNVSILTLCDATTGVCT
             160       170       180       190       200       210 

       360       370       380       390       400       410       
pF1KB3 KKHEDESEAWLHRQNEEPVFSKDGRKFFFIRAIPQGGRGKFYHITVSSSQPNSSNDNIQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKHEDESEAWLHRQNEEPVFSKDGRKFFFIRAIPQGGRGKFYHITVSSSQPNSSNDNIQS
             220       230       240       250       260       270 

       420       430       440       450       460       470       
pF1KB3 ITSGDWDVTKILAYDEKGNKIYFLSTEDLPRRRQLYSANTVGNFNRQCLSCDLVENCTYF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ITSGDWDVTKILAYDEKGNKIYFLSTEDLPRRRQLYSANTVGNFNRQCLSCDLVENCTYF
             280       290       300       310       320       330 

       480       490       500       510       520       530       
pF1KB3 SASFSHSMDFFLLKCEGPGVPMVTVHNTTDKKKMFDLETNEHVKKAINDRQMPKVEYRDI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SASFSHSMDFFLLKCEGPGVPMVTVHNTTDKKKMFDLETNEHVKKAINDRQMPKVEYRDI
             340       350       360       370       380       390 

       540       550       560       570       580       590       
pF1KB3 EIDDYNLPMQILKPATFTDTTHYPLLLVVDGTPGSQSVAEKFEVSWETVMVSSHGAVVVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EIDDYNLPMQILKPATFTDTTHYPLLLVVDGTPGSQSVAEKFEVSWETVMVSSHGAVVVK
             400       410       420       430       440       450 

       600       610       620       630       640       650       
pF1KB3 CDGRGSGFQGTKLLHEVRRRLGLLEEKDQMEAVRTMLKEQYIDRTRVAVFGKDYGGYLST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CDGRGSGFQGTKLLHEVRRRLGLLEEKDQMEAVRTMLKEQYIDRTRVAVFGKDYGGYLST
             460       470       480       490       500       510 

       660       670       680       690       700       710       
pF1KB3 YILPAKGENQGQTFTCGSALSPITDFKLYASAFSERYLGLHGLDNRAYEMTKVAHRVSAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YILPAKGENQGQTFTCGSALSPITDFKLYASAFSERYLGLHGLDNRAYEMTKVAHRVSAL
             520       530       540       550       560       570 

       720       730       740       750       760       770       
pF1KB3 EEQQFLIIHPTADEKIHFQHTAELITQLIRGKANYSLQIYPDESHYFTSSSLKQHLYRSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEQQFLIIHPTADEKIHFQHTAELITQLIRGKANYSLQIYPDESHYFTSSSLKQHLYRSI
             580       590       600       610       620       630 

       780       790       800   
pF1KB3 INFFVECFRIQDKLPTVTAKEDEEED
       :::::::::::::: :::::::::::
XP_016 INFFVECFRIQDKLLTVTAKEDEEED
             640       650       

>>NP_001277181 (OMIM: 126141,612956,616311) dipeptidyl a  (758 aa)
 initn: 4092 init1: 4092 opt: 4092  Z-score: 4977.4  bits: 931.8 E(85289):    0
Smith-Waterman score: 4928; 94.3% identity (94.3% similar) in 803 aa overlap (1-803:1-758)

               10        20        30        40        50        60
pF1KB3 MTTAKEPSASGKSVQQQEQELVGSNPPQRNWKGIAIALLVILVICSLIVTSVILLTPAED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTTAKEPSASGKSVQQQEQELVGSNPPQRNWKGIAIALLVILVICSLIVTSVILLTPAED
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 NSLSQKKKVTVEDLFSEDFKIHDPEAKWISDTEFIYREQKGTVRLWNVETNTSTVLIEGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NSLSQKKKVTVEDLFSEDFKIHDPEAKWISDTEFIYREQKGTVRLWNVETNTSTVLIEGK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 KIESLRAIRYEISPDREYALFSYNVEPIYQHSYTGYYVLSKIPHGDPQSLDPPEVSNAKL
       ::::::::::::::::::::::::::::                                
NP_001 KIESLRAIRYEISPDREYALFSYNVEPI--------------------------------
              130       140                                        

              190       200       210       220       230       240
pF1KB3 QYAGWGPKGQQLIFIFENNIYYCAHVGKQAIRVVSTGKEGVIYNGLSDWLYEEEILKTHI
                    :::::::::::::::::::::::::::::::::::::::::::::::
NP_001 -------------FIFENNIYYCAHVGKQAIRVVSTGKEGVIYNGLSDWLYEEEILKTHI
                   150       160       170       180       190     

              250       260       270       280       290       300
pF1KB3 AHWWSPDGTRLAYAAINDSRVPIMELPTYTGSIYPTVKPYHYPKAGSENPSISLHVIGLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AHWWSPDGTRLAYAAINDSRVPIMELPTYTGSIYPTVKPYHYPKAGSENPSISLHVIGLN
         200       210       220       230       240       250     

              310       320       330       340       350       360
pF1KB3 GPTHDLEMMPPDDPRMREYYITMVKWATSTKVAVTWLNRAQNVSILTLCDATTGVCTKKH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPTHDLEMMPPDDPRMREYYITMVKWATSTKVAVTWLNRAQNVSILTLCDATTGVCTKKH
         260       270       280       290       300       310     

              370       380       390       400       410       420
pF1KB3 EDESEAWLHRQNEEPVFSKDGRKFFFIRAIPQGGRGKFYHITVSSSQPNSSNDNIQSITS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDESEAWLHRQNEEPVFSKDGRKFFFIRAIPQGGRGKFYHITVSSSQPNSSNDNIQSITS
         320       330       340       350       360       370     

              430       440       450       460       470       480
pF1KB3 GDWDVTKILAYDEKGNKIYFLSTEDLPRRRQLYSANTVGNFNRQCLSCDLVENCTYFSAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GDWDVTKILAYDEKGNKIYFLSTEDLPRRRQLYSANTVGNFNRQCLSCDLVENCTYFSAS
         380       390       400       410       420       430     

              490       500       510       520       530       540
pF1KB3 FSHSMDFFLLKCEGPGVPMVTVHNTTDKKKMFDLETNEHVKKAINDRQMPKVEYRDIEID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FSHSMDFFLLKCEGPGVPMVTVHNTTDKKKMFDLETNEHVKKAINDRQMPKVEYRDIEID
         440       450       460       470       480       490     

              550       560       570       580       590       600
pF1KB3 DYNLPMQILKPATFTDTTHYPLLLVVDGTPGSQSVAEKFEVSWETVMVSSHGAVVVKCDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DYNLPMQILKPATFTDTTHYPLLLVVDGTPGSQSVAEKFEVSWETVMVSSHGAVVVKCDG
         500       510       520       530       540       550     

              610       620       630       640       650       660
pF1KB3 RGSGFQGTKLLHEVRRRLGLLEEKDQMEAVRTMLKEQYIDRTRVAVFGKDYGGYLSTYIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGSGFQGTKLLHEVRRRLGLLEEKDQMEAVRTMLKEQYIDRTRVAVFGKDYGGYLSTYIL
         560       570       580       590       600       610     

              670       680       690       700       710       720
pF1KB3 PAKGENQGQTFTCGSALSPITDFKLYASAFSERYLGLHGLDNRAYEMTKVAHRVSALEEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PAKGENQGQTFTCGSALSPITDFKLYASAFSERYLGLHGLDNRAYEMTKVAHRVSALEEQ
         620       630       640       650       660       670     

              730       740       750       760       770       780
pF1KB3 QFLIIHPTADEKIHFQHTAELITQLIRGKANYSLQIYPDESHYFTSSSLKQHLYRSIINF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QFLIIHPTADEKIHFQHTAELITQLIRGKANYSLQIYPDESHYFTSSSLKQHLYRSIINF
         680       690       700       710       720       730     

              790       800   
pF1KB3 FVECFRIQDKLPTVTAKEDEEED
       ::::::::::: :::::::::::
NP_001 FVECFRIQDKLLTVTAKEDEEED
         740       750        

>>NP_001171505 (OMIM: 608209) inactive dipeptidyl peptid  (800 aa)
 initn: 1987 init1: 1621 opt: 2902  Z-score: 3527.9  bits: 663.7 E(85289): 9.1e-190
Smith-Waterman score: 2902; 52.2% identity (80.3% similar) in 809 aa overlap (1-803:1-800)

                    10        20        30        40        50     
pF1KB3 MTTAKE-----PSASGKSVQQQEQELVGSNPPQRNWKGIAIALLVILVICSLIVTSVILL
       ::.::.     :.: ....:  .::: ...::::::::::::::::::.::::. :::::
NP_001 MTAAKQEPQPTPGARASQAQPADQELGSNSPPQRNWKGIAIALLVILVVCSLITMSVILL
               10        20        30        40        50        60

          60        70        80        90       100       110     
pF1KB3 TPAEDNSLSQKKKVTVEDLFSEDFKIHDPEAKWISDTEFIYREQKGTVRLWNVETNTSTV
       :: : .. :.. ....:::: .:: .:::::.::.::. .:. ..: :   :.:::..:.
NP_001 TPDELTN-SSETRLSLEDLFRKDFVLHDPEARWINDTDVVYKSENGHVIKLNIETNATTL
                70        80        90       100       110         

         120       130       140       150       160       170     
pF1KB3 LIEGKKIESLRAIRYEISPDREYALFSYNVEPIYQHSYTGYYVLSKIPHGDPQSLDPPEV
       :.:.  . ...: :. .::: .:.:..:.:. :...:::. ::. .:   .   :.::::
NP_001 LLENTTFVTFKASRHSVSPDLKYVLLAYDVKQIFHYSYTASYVIYNIHTREVWELNPPEV
     120       130       140       150       160       170         

         180       190       200       210       220       230     
pF1KB3 SNAKLQYAGWGPKGQQLIFIFENNIYYCAHVGKQAIRVVSTGKEGVIYNGLSDWLYEEEI
        .. ::::.:: .:::::.::::::::   . ....:..:.::: .:.::..:::::::.
NP_001 EDSVLQYAAWGVQGQQLIYIFENNIYYQPDIKSSSLRLTSSGKEEIIFNGIADWLYEEEL
     180       190       200       210       220       230         

         240       250       260       270       280       290     
pF1KB3 LKTHIAHWWSPDGTRLAYAAINDSRVPIMELPTYTGSIYPTVKPYHYPKAGSENPSISLH
       :..:::::::::: :::.  :::: :: : .: .::..::  : : :::::. ::.:.:.
NP_001 LHSHIAHWWSPDGERLAFLMINDSLVPTMVIPRFTGALYPKGKQYPYPKAGQVNPTIKLY
     240       250       260       270       280       290         

         300       310       320       330       340       350     
pF1KB3 VIGLNGPTHDLEMMPPDDPRMREYYITMVKWATSTKVAVTWLNRAQNVSILTLCDATTGV
       :..: :::: ::.::::. . ::::::::::...::..: :::::::.::::.:..:::.
NP_001 VVNLYGPTHTLELMPPDSFKSREYYITMVKWVSNTKTVVRWLNRAQNISILTVCETTTGA
     300       310       320       330       340       350         

         360       370       380       390       400       410     
pF1KB3 CTKKHEDESEAWLHRQNEEPVFSKDGRKFFFIRAIPQGGRGKFYHITVSSSQPNSSNDNI
       :.::.:  :..:: .::::::::.:: :::.   . :::::.:.::..   : .: . ..
NP_001 CSKKYEMTSDTWLSQQNEEPVFSRDGSKFFMTVPVKQGGRGEFHHIAMFLIQSKSEQITV
     360       370       380       390       400       410         

         420       430       440       450       460       470     
pF1KB3 QSITSGDWDVTKILAYDEKGNKIYFLSTEDLPRRRQLYSANTVGNFNRQCLSCDLV-ENC
       . .:::.:.: :::::::  .::::::::. :: ::::::.: : .::::.::... :.:
NP_001 RHLTSGNWEVIKILAYDETTQKIYFLSTESSPRGRQLYSASTEGLLNRQCISCNFMKEQC
     420       430       440       450       460       470         

          480       490       500       510       520       530    
pF1KB3 TYFSASFSHSMDFFLLKCEGPGVPMVTVHNTTDKKKMFDLETNEHVKKAINDRQMPKVEY
       :::.::::   . ::: :::: ::.:..:.: .  :.: ::.:  .:.::  ... : : 
NP_001 TYFDASFSPMNQHFLLFCEGPRVPVVSLHSTDNPAKYFILESNSMLKEAILKKKIGKPEI
     480       490       500       510       520       530         

          540       550       560       570       580       590    
pF1KB3 RDIEIDDYNLPMQILKPATFTDTTHYPLLLVVDGTPGSQSVAEKFEVSWETVMVSSHGAV
       . ..::::.::.:.  :  : : ..: :::..:  ::.: :..::...:..:...  ...
NP_001 KILHIDDYELPLQLSLPKDFMDRNQYALLLIMDEEPGGQLVTDKFHIDWDSVLIDMDNVI
     540       550       560       570       580       590         

          600       610       620       630       640       650    
pF1KB3 VVKCDGRGSGFQGTKLLHEVRRRLGLLEEKDQMEAVRTMLKEQYIDRTRVAVFGKDYGGY
       :.. ::::::::: :.:.:..:::: .: :::. ::. .::  :::  :...::: ::::
NP_001 VARFDGRGSGFQGLKILQEIHRRLGSVEVKDQITAVKFLLKLPYIDSKRLSIFGKGYGGY
     600       610       620       630       640       650         

          660       670       680       690       700       710    
pF1KB3 LSTYILPAKGENQGQTFTCGSALSPITDFKLYASAFSERYLGLHGLDNRAYEMTKVAHRV
       ....::    ... . : :::...::::.:::::::::::::. . .. .:. ..: : :
NP_001 IASMIL----KSDEKLFKCGSVVAPITDLKLYASAFSERYLGMPSKEESTYQAASVLHNV
     660           670       680       690       700       710     

          720       730       740       750       760       770    
pF1KB3 SALEEQQFLIIHPTADEKIHFQHTAELITQLIRGKANYSLQIYPDESHYFTSSSLKQHLY
        .:.:...:::: ::: :.::::.:::: .::.. .::..:.::::.:  . .: : :::
NP_001 HGLKEENILIIHGTADTKVHFQHSAELIKHLIKAGVNYTMQVYPDEGHNVSEKS-KYHLY
         720       730       740       750       760        770    

          780       790       800   
pF1KB3 RSIINFFVECFRIQDKLPTVTAKEDEEED
        .:..:: .:..   .  .:  .: ::..
NP_001 STILKFFSDCLK---EEISVLPQEPEEDE
          780          790       800




803 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 12:25:11 2016 done: Thu Nov  3 12:25:12 2016
 Total Scan time:  8.150 Total Display time:  0.240

Function used was FASTA [36.3.4 Apr, 2011]
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