Result of FASTA (omim) for pF1KB3047
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB3047, 1147 aa
  1>>>pF1KB3047 1147 - 1147 aa - 1147 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 9.4224+/-0.000557; mu= 2.6746+/- 0.035
 mean_var=214.2378+/-42.439, 0's: 0 Z-trim(114.1): 72  B-trim: 539 in 1/53
 Lambda= 0.087625
 statistics sampled from 23676 (23744) to 23676 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.614), E-opt: 0.2 (0.278), width:  16
 Scan time: 14.870

The best scores are:                                      opt bits E(85289)
NP_002904 (OMIM: 102579) replication factor C subu (1147) 7384 947.7       0
NP_001191676 (OMIM: 102579) replication factor C s (1148) 7372 946.2       0
XP_016864017 (OMIM: 102579) PREDICTED: replication (1121) 5919 762.5       0
XP_011512032 (OMIM: 102579) PREDICTED: replication (1122) 5896 759.6 2.4e-218
XP_011512033 (OMIM: 102579) PREDICTED: replication ( 978) 3274 428.1 1.3e-118
XP_011528502 (OMIM: 105400,162230,616924) PREDICTE ( 924)  266 47.8 0.00036
NP_066554 (OMIM: 105400,162230,616924) neurofilame (1020)  240 44.6  0.0038


>>NP_002904 (OMIM: 102579) replication factor C subunit   (1147 aa)
 initn: 7384 init1: 7384 opt: 7384  Z-score: 5057.6  bits: 947.7 E(85289):    0
Smith-Waterman score: 7384; 100.0% identity (100.0% similar) in 1147 aa overlap (1-1147:1-1147)

               10        20        30        40        50        60
pF1KB3 MDIRKFFGVIPSGKKLVSETVKKNEKTKSDEETLKAKKGIKEIKVNSSRKEDDFKQKQPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MDIRKFFGVIPSGKKLVSETVKKNEKTKSDEETLKAKKGIKEIKVNSSRKEDDFKQKQPS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 KKKRIIYDSDSESEETLQVKNAKKPPEKLPVSSKPGKISRQDPVTYISETDEEDDFMCKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KKKRIIYDSDSESEETLQVKNAKKPPEKLPVSSKPGKISRQDPVTYISETDEEDDFMCKK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 AASKSKENGRSTNSHLGTSNMKKNEENTKTKNKPLSPIKLTPTSVLDYFGTGSVQRSNKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 AASKSKENGRSTNSHLGTSNMKKNEENTKTKNKPLSPIKLTPTSVLDYFGTGSVQRSNKK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 MVASKRKELSQNTDESGLNDEAIAKQLQLDEDAELERQLHEDEEFARTLAMLDEEPKTKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MVASKRKELSQNTDESGLNDEAIAKQLQLDEDAELERQLHEDEEFARTLAMLDEEPKTKK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 ARKDTEAGETFSSVQANLSKAEKHKYPHKVKTAQVSDERKSYSPRKQSKYESSKESQQHS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ARKDTEAGETFSSVQANLSKAEKHKYPHKVKTAQVSDERKSYSPRKQSKYESSKESQQHS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 KSSADKIGEVSSPKASSKLAIMKRKEESSYKEIEPVASKRKENAIKLKGETKTPKKTKSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KSSADKIGEVSSPKASSKLAIMKRKEESSYKEIEPVASKRKENAIKLKGETKTPKKTKSS
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 PAKKESVSPEDSEKKRTNYQAYRSYLNREGPKALGSKEIPKGAENCLEGLIFVITGVLES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PAKKESVSPEDSEKKRTNYQAYRSYLNREGPKALGSKEIPKGAENCLEGLIFVITGVLES
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 IERDEAKSLIERYGGKVTGNVSKKTNYLVMGRDSGQSKSDKAAALGTKIIDEDGLLNLIR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 IERDEAKSLIERYGGKVTGNVSKKTNYLVMGRDSGQSKSDKAAALGTKIIDEDGLLNLIR
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB3 TMPGKKSKYEIAVETEMKKESKLERTPQKNVQGKRKISPSKKESESKKSRPTSKRDSLAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TMPGKKSKYEIAVETEMKKESKLERTPQKNVQGKRKISPSKKESESKKSRPTSKRDSLAK
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB3 TIKKETDVFWKSLDFKEQVAEETSGDSKARNLADDSSENKVENLLWVDKYKPTSLKTIIG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TIKKETDVFWKSLDFKEQVAEETSGDSKARNLADDSSENKVENLLWVDKYKPTSLKTIIG
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB3 QQGDQSCANKLLRWLRNWQKSSSEDKKHAKFGKFSGKDDGSSFKAALLSGPPGVGKTTTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 QQGDQSCANKLLRWLRNWQKSSSEDKKHAKFGKFSGKDDGSSFKAALLSGPPGVGKTTTA
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB3 SLVCQELGYSYVELNASDTRSKSSLKAIVAESLNNTSIKGFYSNGAASSVSTKHALIMDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SLVCQELGYSYVELNASDTRSKSSLKAIVAESLNNTSIKGFYSNGAASSVSTKHALIMDE
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB3 VDGMAGNEDRGGIQELIGLIKHTKIPIICMCNDRNHPKIRSLVHYCFDLRFQRPRVEQIK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VDGMAGNEDRGGIQELIGLIKHTKIPIICMCNDRNHPKIRSLVHYCFDLRFQRPRVEQIK
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB3 GAMMSIAFKEGLKIPPPAMNEIILGANQDIRQVLHNLSMWCARSKALTYDQAKADSHRAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GAMMSIAFKEGLKIPPPAMNEIILGANQDIRQVLHNLSMWCARSKALTYDQAKADSHRAK
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB3 KDIKMGPFDVARKVFAAGEETAHMSLVDKSDLFFHDYSIAPLFVQENYIHVKPVAAGGDM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KDIKMGPFDVARKVFAAGEETAHMSLVDKSDLFFHDYSIAPLFVQENYIHVKPVAAGGDM
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB3 KKHLMLLSRAADSICDGDLVDSQIRSKQNWSLLPAQAIYASVLPGELMRGYMTQFPTFPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KKHLMLLSRAADSICDGDLVDSQIRSKQNWSLLPAQAIYASVLPGELMRGYMTQFPTFPS
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KB3 WLGKHSSTGKHDRIVQDLALHMSLRTYSSKRTVNMDYLSLLRDALVQPLTSQGVDGVQDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 WLGKHSSTGKHDRIVQDLALHMSLRTYSSKRTVNMDYLSLLRDALVQPLTSQGVDGVQDV
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KB3 VALMDTYYLMKEDFENIMEISSWGGKPSPFSKLDPKVKAAFTRAYNKEAHLTPYSLQAIK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VALMDTYYLMKEDFENIMEISSWGGKPSPFSKLDPKVKAAFTRAYNKEAHLTPYSLQAIK
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KB3 ASRHSTSPSLDSEYNEELNEDDSQSDEKDQDAIETDAMIKKKTKSSKPSKPEKDKEPRKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ASRHSTSPSLDSEYNEELNEDDSQSDEKDQDAIETDAMIKKKTKSSKPSKPEKDKEPRKG
             1090      1100      1110      1120      1130      1140

              
pF1KB3 KGKSSKK
       :::::::
NP_002 KGKSSKK
              

>>NP_001191676 (OMIM: 102579) replication factor C subun  (1148 aa)
 initn: 3975 init1: 3975 opt: 7372  Z-score: 5049.4  bits: 946.2 E(85289):    0
Smith-Waterman score: 7372; 99.9% identity (99.9% similar) in 1148 aa overlap (1-1147:1-1148)

               10        20        30        40        50        60
pF1KB3 MDIRKFFGVIPSGKKLVSETVKKNEKTKSDEETLKAKKGIKEIKVNSSRKEDDFKQKQPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDIRKFFGVIPSGKKLVSETVKKNEKTKSDEETLKAKKGIKEIKVNSSRKEDDFKQKQPS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 KKKRIIYDSDSESEETLQVKNAKKPPEKLPVSSKPGKISRQDPVTYISETDEEDDFMCKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKKRIIYDSDSESEETLQVKNAKKPPEKLPVSSKPGKISRQDPVTYISETDEEDDFMCKK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 AASKSKENGRSTNSHLGTSNMKKNEENTKTKNKPLSPIKLTPTSVLDYFGTGSVQRSNKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AASKSKENGRSTNSHLGTSNMKKNEENTKTKNKPLSPIKLTPTSVLDYFGTGSVQRSNKK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 MVASKRKELSQNTDESGLNDEAIAKQLQLDEDAELERQLHEDEEFARTLAMLDEEPKTKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVASKRKELSQNTDESGLNDEAIAKQLQLDEDAELERQLHEDEEFARTLAMLDEEPKTKK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 ARKDTEAGETFSSVQANLSKAEKHKYPHKVKTAQVSDERKSYSPRKQSKYESSKESQQHS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARKDTEAGETFSSVQANLSKAEKHKYPHKVKTAQVSDERKSYSPRKQSKYESSKESQQHS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 KSSADKIGEVSSPKASSKLAIMKRKEESSYKEIEPVASKRKENAIKLKGETKTPKKTKSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSSADKIGEVSSPKASSKLAIMKRKEESSYKEIEPVASKRKENAIKLKGETKTPKKTKSS
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 PAKKESVSPEDSEKKRTNYQAYRSYLNREGPKALGSKEIPKGAENCLEGLIFVITGVLES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PAKKESVSPEDSEKKRTNYQAYRSYLNREGPKALGSKEIPKGAENCLEGLIFVITGVLES
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 IERDEAKSLIERYGGKVTGNVSKKTNYLVMGRDSGQSKSDKAAALGTKIIDEDGLLNLIR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IERDEAKSLIERYGGKVTGNVSKKTNYLVMGRDSGQSKSDKAAALGTKIIDEDGLLNLIR
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB3 TMPGKKSKYEIAVETEMKKESKLERTPQKNVQGKRKISPSKKESESKKSRPTSKRDSLAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TMPGKKSKYEIAVETEMKKESKLERTPQKNVQGKRKISPSKKESESKKSRPTSKRDSLAK
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB3 TIKKETDVFWKSLDFKEQVAEETSGDSKARNLADDSSENKVENLLWVDKYKPTSLKTIIG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TIKKETDVFWKSLDFKEQVAEETSGDSKARNLADDSSENKVENLLWVDKYKPTSLKTIIG
              550       560       570       580       590       600

              610       620        630       640       650         
pF1KB3 QQGDQSCANKLLRWLRNWQKSSSEDKKHA-KFGKFSGKDDGSSFKAALLSGPPGVGKTTT
       ::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::::
NP_001 QQGDQSCANKLLRWLRNWQKSSSEDKKHAAKFGKFSGKDDGSSFKAALLSGPPGVGKTTT
              610       620       630       640       650       660

     660       670       680       690       700       710         
pF1KB3 ASLVCQELGYSYVELNASDTRSKSSLKAIVAESLNNTSIKGFYSNGAASSVSTKHALIMD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASLVCQELGYSYVELNASDTRSKSSLKAIVAESLNNTSIKGFYSNGAASSVSTKHALIMD
              670       680       690       700       710       720

     720       730       740       750       760       770         
pF1KB3 EVDGMAGNEDRGGIQELIGLIKHTKIPIICMCNDRNHPKIRSLVHYCFDLRFQRPRVEQI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVDGMAGNEDRGGIQELIGLIKHTKIPIICMCNDRNHPKIRSLVHYCFDLRFQRPRVEQI
              730       740       750       760       770       780

     780       790       800       810       820       830         
pF1KB3 KGAMMSIAFKEGLKIPPPAMNEIILGANQDIRQVLHNLSMWCARSKALTYDQAKADSHRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGAMMSIAFKEGLKIPPPAMNEIILGANQDIRQVLHNLSMWCARSKALTYDQAKADSHRA
              790       800       810       820       830       840

     840       850       860       870       880       890         
pF1KB3 KKDIKMGPFDVARKVFAAGEETAHMSLVDKSDLFFHDYSIAPLFVQENYIHVKPVAAGGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKDIKMGPFDVARKVFAAGEETAHMSLVDKSDLFFHDYSIAPLFVQENYIHVKPVAAGGD
              850       860       870       880       890       900

     900       910       920       930       940       950         
pF1KB3 MKKHLMLLSRAADSICDGDLVDSQIRSKQNWSLLPAQAIYASVLPGELMRGYMTQFPTFP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKKHLMLLSRAADSICDGDLVDSQIRSKQNWSLLPAQAIYASVLPGELMRGYMTQFPTFP
              910       920       930       940       950       960

     960       970       980       990      1000      1010         
pF1KB3 SWLGKHSSTGKHDRIVQDLALHMSLRTYSSKRTVNMDYLSLLRDALVQPLTSQGVDGVQD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SWLGKHSSTGKHDRIVQDLALHMSLRTYSSKRTVNMDYLSLLRDALVQPLTSQGVDGVQD
              970       980       990      1000      1010      1020

    1020      1030      1040      1050      1060      1070         
pF1KB3 VVALMDTYYLMKEDFENIMEISSWGGKPSPFSKLDPKVKAAFTRAYNKEAHLTPYSLQAI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVALMDTYYLMKEDFENIMEISSWGGKPSPFSKLDPKVKAAFTRAYNKEAHLTPYSLQAI
             1030      1040      1050      1060      1070      1080

    1080      1090      1100      1110      1120      1130         
pF1KB3 KASRHSTSPSLDSEYNEELNEDDSQSDEKDQDAIETDAMIKKKTKSSKPSKPEKDKEPRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KASRHSTSPSLDSEYNEELNEDDSQSDEKDQDAIETDAMIKKKTKSSKPSKPEKDKEPRK
             1090      1100      1110      1120      1130      1140

    1140       
pF1KB3 GKGKSSKK
       ::::::::
NP_001 GKGKSSKK
               

>>XP_016864017 (OMIM: 102579) PREDICTED: replication fac  (1121 aa)
 initn: 5868 init1: 5868 opt: 5919  Z-score: 4056.8  bits: 762.5 E(85289):    0
Smith-Waterman score: 7156; 97.7% identity (97.7% similar) in 1147 aa overlap (1-1147:1-1121)

               10        20        30        40        50        60
pF1KB3 MDIRKFFGVIPSGKKLVSETVKKNEKTKSDEETLKAKKGIKEIKVNSSRKEDDFKQKQPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDIRKFFGVIPSGKKLVSETVKKNEKTKSDEETLKAKKGIKEIKVNSSRKEDDFKQKQPS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 KKKRIIYDSDSESEETLQVKNAKKPPEKLPVSSKPGKISRQDPVTYISETDEEDDFMCKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKKRIIYDSDSESEETLQVKNAKKPPEKLPVSSKPGKISRQDPVTYISETDEEDDFMCKK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 AASKSKENGRSTNSHLGTSNMKKNEENTKTKNKPLSPIKLTPTSVLDYFGTGSVQRSNKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AASKSKENGRSTNSHLGTSNMKKNEENTKTKNKPLSPIKLTPTSVLDYFGTGSVQRSNKK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 MVASKRKELSQNTDESGLNDEAIAKQLQLDEDAELERQLHEDEEFARTLAMLDEEPKTKK
       ::::::::::::::::::::::::::::::::::                          
XP_016 MVASKRKELSQNTDESGLNDEAIAKQLQLDEDAE--------------------------
              190       200       210                              

              250       260       270       280       290       300
pF1KB3 ARKDTEAGETFSSVQANLSKAEKHKYPHKVKTAQVSDERKSYSPRKQSKYESSKESQQHS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARKDTEAGETFSSVQANLSKAEKHKYPHKVKTAQVSDERKSYSPRKQSKYESSKESQQHS
          220       230       240       250       260       270    

              310       320       330       340       350       360
pF1KB3 KSSADKIGEVSSPKASSKLAIMKRKEESSYKEIEPVASKRKENAIKLKGETKTPKKTKSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSSADKIGEVSSPKASSKLAIMKRKEESSYKEIEPVASKRKENAIKLKGETKTPKKTKSS
          280       290       300       310       320       330    

              370       380       390       400       410       420
pF1KB3 PAKKESVSPEDSEKKRTNYQAYRSYLNREGPKALGSKEIPKGAENCLEGLIFVITGVLES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PAKKESVSPEDSEKKRTNYQAYRSYLNREGPKALGSKEIPKGAENCLEGLIFVITGVLES
          340       350       360       370       380       390    

              430       440       450       460       470       480
pF1KB3 IERDEAKSLIERYGGKVTGNVSKKTNYLVMGRDSGQSKSDKAAALGTKIIDEDGLLNLIR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IERDEAKSLIERYGGKVTGNVSKKTNYLVMGRDSGQSKSDKAAALGTKIIDEDGLLNLIR
          400       410       420       430       440       450    

              490       500       510       520       530       540
pF1KB3 TMPGKKSKYEIAVETEMKKESKLERTPQKNVQGKRKISPSKKESESKKSRPTSKRDSLAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TMPGKKSKYEIAVETEMKKESKLERTPQKNVQGKRKISPSKKESESKKSRPTSKRDSLAK
          460       470       480       490       500       510    

              550       560       570       580       590       600
pF1KB3 TIKKETDVFWKSLDFKEQVAEETSGDSKARNLADDSSENKVENLLWVDKYKPTSLKTIIG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TIKKETDVFWKSLDFKEQVAEETSGDSKARNLADDSSENKVENLLWVDKYKPTSLKTIIG
          520       530       540       550       560       570    

              610       620       630       640       650       660
pF1KB3 QQGDQSCANKLLRWLRNWQKSSSEDKKHAKFGKFSGKDDGSSFKAALLSGPPGVGKTTTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQGDQSCANKLLRWLRNWQKSSSEDKKHAKFGKFSGKDDGSSFKAALLSGPPGVGKTTTA
          580       590       600       610       620       630    

              670       680       690       700       710       720
pF1KB3 SLVCQELGYSYVELNASDTRSKSSLKAIVAESLNNTSIKGFYSNGAASSVSTKHALIMDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLVCQELGYSYVELNASDTRSKSSLKAIVAESLNNTSIKGFYSNGAASSVSTKHALIMDE
          640       650       660       670       680       690    

              730       740       750       760       770       780
pF1KB3 VDGMAGNEDRGGIQELIGLIKHTKIPIICMCNDRNHPKIRSLVHYCFDLRFQRPRVEQIK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VDGMAGNEDRGGIQELIGLIKHTKIPIICMCNDRNHPKIRSLVHYCFDLRFQRPRVEQIK
          700       710       720       730       740       750    

              790       800       810       820       830       840
pF1KB3 GAMMSIAFKEGLKIPPPAMNEIILGANQDIRQVLHNLSMWCARSKALTYDQAKADSHRAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GAMMSIAFKEGLKIPPPAMNEIILGANQDIRQVLHNLSMWCARSKALTYDQAKADSHRAK
          760       770       780       790       800       810    

              850       860       870       880       890       900
pF1KB3 KDIKMGPFDVARKVFAAGEETAHMSLVDKSDLFFHDYSIAPLFVQENYIHVKPVAAGGDM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDIKMGPFDVARKVFAAGEETAHMSLVDKSDLFFHDYSIAPLFVQENYIHVKPVAAGGDM
          820       830       840       850       860       870    

              910       920       930       940       950       960
pF1KB3 KKHLMLLSRAADSICDGDLVDSQIRSKQNWSLLPAQAIYASVLPGELMRGYMTQFPTFPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKHLMLLSRAADSICDGDLVDSQIRSKQNWSLLPAQAIYASVLPGELMRGYMTQFPTFPS
          880       890       900       910       920       930    

              970       980       990      1000      1010      1020
pF1KB3 WLGKHSSTGKHDRIVQDLALHMSLRTYSSKRTVNMDYLSLLRDALVQPLTSQGVDGVQDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WLGKHSSTGKHDRIVQDLALHMSLRTYSSKRTVNMDYLSLLRDALVQPLTSQGVDGVQDV
          940       950       960       970       980       990    

             1030      1040      1050      1060      1070      1080
pF1KB3 VALMDTYYLMKEDFENIMEISSWGGKPSPFSKLDPKVKAAFTRAYNKEAHLTPYSLQAIK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VALMDTYYLMKEDFENIMEISSWGGKPSPFSKLDPKVKAAFTRAYNKEAHLTPYSLQAIK
         1000      1010      1020      1030      1040      1050    

             1090      1100      1110      1120      1130      1140
pF1KB3 ASRHSTSPSLDSEYNEELNEDDSQSDEKDQDAIETDAMIKKKTKSSKPSKPEKDKEPRKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASRHSTSPSLDSEYNEELNEDDSQSDEKDQDAIETDAMIKKKTKSSKPSKPEKDKEPRKG
         1060      1070      1080      1090      1100      1110    

              
pF1KB3 KGKSSKK
       :::::::
XP_016 KGKSSKK
         1120 

>>XP_011512032 (OMIM: 102579) PREDICTED: replication fac  (1122 aa)
 initn: 4844 init1: 3430 opt: 5896  Z-score: 4041.1  bits: 759.6 E(85289): 2.4e-218
Smith-Waterman score: 7144; 97.6% identity (97.6% similar) in 1148 aa overlap (1-1147:1-1122)

               10        20        30        40        50        60
pF1KB3 MDIRKFFGVIPSGKKLVSETVKKNEKTKSDEETLKAKKGIKEIKVNSSRKEDDFKQKQPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDIRKFFGVIPSGKKLVSETVKKNEKTKSDEETLKAKKGIKEIKVNSSRKEDDFKQKQPS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 KKKRIIYDSDSESEETLQVKNAKKPPEKLPVSSKPGKISRQDPVTYISETDEEDDFMCKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKKRIIYDSDSESEETLQVKNAKKPPEKLPVSSKPGKISRQDPVTYISETDEEDDFMCKK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 AASKSKENGRSTNSHLGTSNMKKNEENTKTKNKPLSPIKLTPTSVLDYFGTGSVQRSNKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AASKSKENGRSTNSHLGTSNMKKNEENTKTKNKPLSPIKLTPTSVLDYFGTGSVQRSNKK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 MVASKRKELSQNTDESGLNDEAIAKQLQLDEDAELERQLHEDEEFARTLAMLDEEPKTKK
       ::::::::::::::::::::::::::::::::::                          
XP_011 MVASKRKELSQNTDESGLNDEAIAKQLQLDEDAE--------------------------
              190       200       210                              

              250       260       270       280       290       300
pF1KB3 ARKDTEAGETFSSVQANLSKAEKHKYPHKVKTAQVSDERKSYSPRKQSKYESSKESQQHS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ARKDTEAGETFSSVQANLSKAEKHKYPHKVKTAQVSDERKSYSPRKQSKYESSKESQQHS
          220       230       240       250       260       270    

              310       320       330       340       350       360
pF1KB3 KSSADKIGEVSSPKASSKLAIMKRKEESSYKEIEPVASKRKENAIKLKGETKTPKKTKSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSSADKIGEVSSPKASSKLAIMKRKEESSYKEIEPVASKRKENAIKLKGETKTPKKTKSS
          280       290       300       310       320       330    

              370       380       390       400       410       420
pF1KB3 PAKKESVSPEDSEKKRTNYQAYRSYLNREGPKALGSKEIPKGAENCLEGLIFVITGVLES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PAKKESVSPEDSEKKRTNYQAYRSYLNREGPKALGSKEIPKGAENCLEGLIFVITGVLES
          340       350       360       370       380       390    

              430       440       450       460       470       480
pF1KB3 IERDEAKSLIERYGGKVTGNVSKKTNYLVMGRDSGQSKSDKAAALGTKIIDEDGLLNLIR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IERDEAKSLIERYGGKVTGNVSKKTNYLVMGRDSGQSKSDKAAALGTKIIDEDGLLNLIR
          400       410       420       430       440       450    

              490       500       510       520       530       540
pF1KB3 TMPGKKSKYEIAVETEMKKESKLERTPQKNVQGKRKISPSKKESESKKSRPTSKRDSLAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TMPGKKSKYEIAVETEMKKESKLERTPQKNVQGKRKISPSKKESESKKSRPTSKRDSLAK
          460       470       480       490       500       510    

              550       560       570       580       590       600
pF1KB3 TIKKETDVFWKSLDFKEQVAEETSGDSKARNLADDSSENKVENLLWVDKYKPTSLKTIIG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TIKKETDVFWKSLDFKEQVAEETSGDSKARNLADDSSENKVENLLWVDKYKPTSLKTIIG
          520       530       540       550       560       570    

              610       620        630       640       650         
pF1KB3 QQGDQSCANKLLRWLRNWQKSSSEDKKHA-KFGKFSGKDDGSSFKAALLSGPPGVGKTTT
       ::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::::
XP_011 QQGDQSCANKLLRWLRNWQKSSSEDKKHAAKFGKFSGKDDGSSFKAALLSGPPGVGKTTT
          580       590       600       610       620       630    

     660       670       680       690       700       710         
pF1KB3 ASLVCQELGYSYVELNASDTRSKSSLKAIVAESLNNTSIKGFYSNGAASSVSTKHALIMD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASLVCQELGYSYVELNASDTRSKSSLKAIVAESLNNTSIKGFYSNGAASSVSTKHALIMD
          640       650       660       670       680       690    

     720       730       740       750       760       770         
pF1KB3 EVDGMAGNEDRGGIQELIGLIKHTKIPIICMCNDRNHPKIRSLVHYCFDLRFQRPRVEQI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVDGMAGNEDRGGIQELIGLIKHTKIPIICMCNDRNHPKIRSLVHYCFDLRFQRPRVEQI
          700       710       720       730       740       750    

     780       790       800       810       820       830         
pF1KB3 KGAMMSIAFKEGLKIPPPAMNEIILGANQDIRQVLHNLSMWCARSKALTYDQAKADSHRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KGAMMSIAFKEGLKIPPPAMNEIILGANQDIRQVLHNLSMWCARSKALTYDQAKADSHRA
          760       770       780       790       800       810    

     840       850       860       870       880       890         
pF1KB3 KKDIKMGPFDVARKVFAAGEETAHMSLVDKSDLFFHDYSIAPLFVQENYIHVKPVAAGGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKDIKMGPFDVARKVFAAGEETAHMSLVDKSDLFFHDYSIAPLFVQENYIHVKPVAAGGD
          820       830       840       850       860       870    

     900       910       920       930       940       950         
pF1KB3 MKKHLMLLSRAADSICDGDLVDSQIRSKQNWSLLPAQAIYASVLPGELMRGYMTQFPTFP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKKHLMLLSRAADSICDGDLVDSQIRSKQNWSLLPAQAIYASVLPGELMRGYMTQFPTFP
          880       890       900       910       920       930    

     960       970       980       990      1000      1010         
pF1KB3 SWLGKHSSTGKHDRIVQDLALHMSLRTYSSKRTVNMDYLSLLRDALVQPLTSQGVDGVQD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SWLGKHSSTGKHDRIVQDLALHMSLRTYSSKRTVNMDYLSLLRDALVQPLTSQGVDGVQD
          940       950       960       970       980       990    

    1020      1030      1040      1050      1060      1070         
pF1KB3 VVALMDTYYLMKEDFENIMEISSWGGKPSPFSKLDPKVKAAFTRAYNKEAHLTPYSLQAI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVALMDTYYLMKEDFENIMEISSWGGKPSPFSKLDPKVKAAFTRAYNKEAHLTPYSLQAI
         1000      1010      1020      1030      1040      1050    

    1080      1090      1100      1110      1120      1130         
pF1KB3 KASRHSTSPSLDSEYNEELNEDDSQSDEKDQDAIETDAMIKKKTKSSKPSKPEKDKEPRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KASRHSTSPSLDSEYNEELNEDDSQSDEKDQDAIETDAMIKKKTKSSKPSKPEKDKEPRK
         1060      1070      1080      1090      1100      1110    

    1140       
pF1KB3 GKGKSSKK
       ::::::::
XP_011 GKGKSSKK
         1120  

>>XP_011512033 (OMIM: 102579) PREDICTED: replication fac  (978 aa)
 initn: 3179 init1: 3179 opt: 3274  Z-score: 2250.6  bits: 428.1 E(85289): 1.3e-118
Smith-Waterman score: 5934; 85.3% identity (85.3% similar) in 1147 aa overlap (1-1147:1-978)

               10        20        30        40        50        60
pF1KB3 MDIRKFFGVIPSGKKLVSETVKKNEKTKSDEETLKAKKGIKEIKVNSSRKEDDFKQKQPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDIRKFFGVIPSGKKLVSETVKKNEKTKSDEETLKAKKGIKEIKVNSSRKEDDFKQKQPS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 KKKRIIYDSDSESEETLQVKNAKKPPEKLPVSSKPGKISRQDPVTYISETDEEDDFMCKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKKRIIYDSDSESEETLQVKNAKKPPEKLPVSSKPGKISRQDPVTYISETDEEDDFMCKK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 AASKSKENGRSTNSHLGTSNMKKNEENTKTKNKPLSPIKLTPTSVLDYFGTGSVQRSNKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AASKSKENGRSTNSHLGTSNMKKNEENTKTKNKPLSPIKLTPTSVLDYFGTGSVQRSNKK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 MVASKRKELSQNTDESGLNDEAIAKQLQLDEDAELERQLHEDEEFARTLAMLDEEPKTKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MVASKRKELSQNTDESGLNDEAIAKQLQLDEDAELERQLHEDEEFARTLAMLDEEPKTKK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 ARKDTEAGETFSSVQANLSKAEKHKYPHKVKTAQVSDERKSYSPRKQSKYESSKESQQHS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ARKDTEAGETFSSVQANLSKAEKHKYPHKVKTAQVSDERKSYSPRKQSKYESSKESQQHS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 KSSADKIGEVSSPKASSKLAIMKRKEESSYKEIEPVASKRKENAIKLKGETKTPKKTKSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSSADKIGEVSSPKASSKLAIMKRKEESSYKEIEPVASKRKENAIKLKGETKTPKKTKSS
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 PAKKESVSPEDSEKKRTNYQAYRSYLNREGPKALGSKEIPKGAENCLEGLIFVITGVLES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PAKKESVSPEDSEKKRTNYQAYRSYLNREGPKALGSKEIPKGAENCLEGLIFVITGVLES
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 IERDEAKSLIERYGGKVTGNVSKKTNYLVMGRDSGQSKSDKAAALGTKIIDEDGLLNLIR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IERDEAKSLIERYGGKVTGNVSKKTNYLVMGRDSGQSKSDKAAALGTKIIDEDGLLNLIR
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB3 TMPGKKSKYEIAVETEMKKESKLERTPQKNVQGKRKISPSKKESESKKSRPTSKRDSLAK
       ::::::::::::::::                                            
XP_011 TMPGKKSKYEIAVETE--------------------------------------------
              490                                                  

              550       560       570       580       590       600
pF1KB3 TIKKETDVFWKSLDFKEQVAEETSGDSKARNLADDSSENKVENLLWVDKYKPTSLKTIIG
                                                                   
XP_011 ------------------------------------------------------------
                                                                   

              610       620       630       640       650       660
pF1KB3 QQGDQSCANKLLRWLRNWQKSSSEDKKHAKFGKFSGKDDGSSFKAALLSGPPGVGKTTTA
                                                                   
XP_011 ------------------------------------------------------------
                                                                   

              670       680       690       700       710       720
pF1KB3 SLVCQELGYSYVELNASDTRSKSSLKAIVAESLNNTSIKGFYSNGAASSVSTKHALIMDE
            :::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 -----ELGYSYVELNASDTRSKSSLKAIVAESLNNTSIKGFYSNGAASSVSTKHALIMDE
             500       510       520       530       540       550 

              730       740       750       760       770       780
pF1KB3 VDGMAGNEDRGGIQELIGLIKHTKIPIICMCNDRNHPKIRSLVHYCFDLRFQRPRVEQIK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VDGMAGNEDRGGIQELIGLIKHTKIPIICMCNDRNHPKIRSLVHYCFDLRFQRPRVEQIK
             560       570       580       590       600       610 

              790       800       810       820       830       840
pF1KB3 GAMMSIAFKEGLKIPPPAMNEIILGANQDIRQVLHNLSMWCARSKALTYDQAKADSHRAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GAMMSIAFKEGLKIPPPAMNEIILGANQDIRQVLHNLSMWCARSKALTYDQAKADSHRAK
             620       630       640       650       660       670 

              850       860       870       880       890       900
pF1KB3 KDIKMGPFDVARKVFAAGEETAHMSLVDKSDLFFHDYSIAPLFVQENYIHVKPVAAGGDM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KDIKMGPFDVARKVFAAGEETAHMSLVDKSDLFFHDYSIAPLFVQENYIHVKPVAAGGDM
             680       690       700       710       720       730 

              910       920       930       940       950       960
pF1KB3 KKHLMLLSRAADSICDGDLVDSQIRSKQNWSLLPAQAIYASVLPGELMRGYMTQFPTFPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKHLMLLSRAADSICDGDLVDSQIRSKQNWSLLPAQAIYASVLPGELMRGYMTQFPTFPS
             740       750       760       770       780       790 

              970       980       990      1000      1010      1020
pF1KB3 WLGKHSSTGKHDRIVQDLALHMSLRTYSSKRTVNMDYLSLLRDALVQPLTSQGVDGVQDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WLGKHSSTGKHDRIVQDLALHMSLRTYSSKRTVNMDYLSLLRDALVQPLTSQGVDGVQDV
             800       810       820       830       840       850 

             1030      1040      1050      1060      1070      1080
pF1KB3 VALMDTYYLMKEDFENIMEISSWGGKPSPFSKLDPKVKAAFTRAYNKEAHLTPYSLQAIK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VALMDTYYLMKEDFENIMEISSWGGKPSPFSKLDPKVKAAFTRAYNKEAHLTPYSLQAIK
             860       870       880       890       900       910 

             1090      1100      1110      1120      1130      1140
pF1KB3 ASRHSTSPSLDSEYNEELNEDDSQSDEKDQDAIETDAMIKKKTKSSKPSKPEKDKEPRKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASRHSTSPSLDSEYNEELNEDDSQSDEKDQDAIETDAMIKKKTKSSKPSKPEKDKEPRKG
             920       930       940       950       960       970 

              
pF1KB3 KGKSSKK
       :::::::
XP_011 KGKSSKK
              

>>XP_011528502 (OMIM: 105400,162230,616924) PREDICTED: n  (924 aa)
 initn: 185 init1:  70 opt: 266  Z-score: 195.9  bits: 47.8 E(85289): 0.00036
Smith-Waterman score: 268; 23.3% identity (54.2% similar) in 506 aa overlap (174-644:447-924)

           150       160       170       180        190       200  
pF1KB3 NEENTKTKNKPLSPIKLTPTSVLDYFGTGSVQRSNKK-MVASKRKELSQNTDESGLNDEA
                                     :..:.:. ... .. : .: :.:   ..: 
XP_011 PIPFSLPEGLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEK
        420       430       440       450       460       470      

            210       220       230       240       250       260  
pF1KB3 IAKQLQLDEDAELERQLHEDEEFARTLAMLDEEPKTKKARKDTEAGETFSSVQANLSKAE
        ::. .  :.   :..  :  :        .:  . .:  :.    :. : ..:.  . :
XP_011 EAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKE
        480       490       500       510       520       530      

            270       280       290       300       310        320 
pF1KB3 KHKYPHKVKTAQVSDERKSYSPRKQSKYESSKESQQHSKSSADKIGEVSSP-KASSKLAI
       . : : .::. .     :. ::.: .:   ..:...  :...   .:..:: ::.: .  
XP_011 EAKSPAEVKSPE-----KAKSPEK-AKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKA
        540            550        560       570       580       590

             330       340       350       360       370       380 
pF1KB3 MKRKEESSYKEIEPVASKRKENAIKLKGETKTPKKTKSSPAKKESVSPEDSEKKRTNYQA
         .. :.. . ..  :.. ..    .: :.:.:.:.:: :.:.:. .:: . :. .. .:
XP_011 EAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKS-PVKEEAKTPEKA-KSPVKEEA
              600       610       620        630       640         

             390       400       410       420       430       440 
pF1KB3 YRSYLNREGPKALGSKEIPKGAENCLEGLIFVITGVLESIERDEAKSLIERYGGKVTGNV
              ..:.   : :  :  .        : .   ..  ..::.:  ...  :. . :
XP_011 -------KSPEKAKSPEKAKTLD--------VKSPEAKTPAKEEARSPADKFPEKAKSPV
             650       660               670       680       690   

                    450       460       470       480       490    
pF1KB3 S-------KKTNYLVMGRDSGQSKSDKAAALGTKIIDEDGLLNLIRTMPGKKSKYEIAV-
       .       :  . :     . ...  :   . . . .:.   ..    : ::.. : :  
XP_011 KEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPA
           700       710       720       730       740       750   

             500       510                      520       530      
pF1KB3 --ETEMKKESKLERTPQKN-----VQGKR----------KISPSKKESESKKSRPTSKRD
         .:: ::.:: :..:.:.     :. :.          :.  .:.:.:.::. :: ...
XP_011 TPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKE
           760       770       780       790       800       810   

        540              550       560       570       580         
pF1KB3 SLAKTIKKE-------TDVFWKSLDFKEQVAEETSGDSKARNLADDSSENKVENLLWVDK
       . ::.  ::       :.:  :  :  .  :.: :  .. .. : .....: :.    ..
XP_011 APAKVEVKEDAKPKEKTEVAKKEPD--DAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEE
           820       830         840       850       860       870 

     590       600       610        620       630       640        
pF1KB3 YKPTSLKTIIGQQGDQSCANKLLR-WLRNWQKSSSEDKKHAKFGKFSGKDDGSSFKAALL
          :  :   ... :.. ...  .   .. .:::: :.: .:  . . .: ... :    
XP_011 KPKTEAK---AKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKATEDKAAKGK    
                880       890       900       910       920        

      650       660       670       680       690       700        
pF1KB3 SGPPGVGKTTTASLVCQELGYSYVELNASDTRSKSSLKAIVAESLNNTSIKGFYSNGAAS

>>NP_066554 (OMIM: 105400,162230,616924) neurofilament h  (1020 aa)
 initn: 181 init1:  70 opt: 240  Z-score: 177.5  bits: 44.6 E(85289): 0.0038
Smith-Waterman score: 297; 23.7% identity (54.0% similar) in 607 aa overlap (84-644:439-1020)

            60        70        80        90           100         
pF1KB3 FKQKQPSKKKRIIYDSDSESEETLQVKNAKKPPEKLPVSSKPGK----ISRQDPVTYISE
                                     :  ::. :  :  :    . .:   : ..:
NP_066 EECRIGFGPIPFSLPEGLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTE
      410       420       430       440       450       460        

      110       120       130       140         150       160      
pF1KB3 -TDEEDDFMCKKAASKSKENGRSTNSHLGTSNMKK--NEENTKTKNKPLSPIKLTPTSVL
        . ::..   :.  .: .:.:.  ... :  . :.   :: .. ...  ::.:    :  
NP_066 EVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPA
      470       480       490       500       510       520        

        170       180       190       200       210       220      
pF1KB3 DYFGTGSVQRSNKKMVASKRKELSQNTDESGLNDEAIAKQLQLDEDAELERQLHEDEEFA
       .  .  . . ..   : : .:  :   .:.    :: . .    :.:.   ...  :. :
NP_066 EAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPE---KEEAKSPAEVKSPEK-A
      530       540       550       560          570       580     

        230       240       250       260       270       280      
pF1KB3 RTLAMLDEEPKTKKARKDTEAGETFSSVQANLSKAEKHKYPHKVKTAQVSDERKSYSPRK
       .. :   :: :.    :. : ..  : :. . ..  . : : : . :.   : ::  :.:
NP_066 KSPA--KEEAKSPAEAKSPEKAK--SPVKEEAKSPAEAKSPVK-EEAKSPAEVKS--PEK
            590       600         610       620        630         

        290       300       310        320       330       340     
pF1KB3 QSKYESSKESQQHSKSSADKIGEVSSP-KASSKLAIMKRKEESSYKEIEPVASKRKENAI
        .:  ...:...  :... .  :..:: ::.: .    .. :.. . ..  :.. ..   
NP_066 -AKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKS
        640       650       660       670       680       690      

         350       360       370            380       390       400
pF1KB3 KLKGETKTPKKTKSSPAKKESVSPEDS-----EKKRTNYQAYRSYLNREGPKALGSKEIP
        .: :.:.:.:.:: :.:.:. ::: .     :. .:  .: .: ...:. .   .:  :
NP_066 PVKEEAKSPEKAKS-PVKEEAKSPEKAKSPVKEEAKTPEKA-KSPVKEEAKSPEKAKS-P
        700       710        720       730        740       750    

              410       420       430       440              450   
pF1KB3 KGAENCLEGLIFVITGVLESIERDEAKSLIERYGGKVTGNVS-------KKTNYLVMGRD
       . :.. :.    : .   ..  ..::.:  ...  :. . :.       :  . :     
NP_066 EKAKT-LD----VKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAK
            760           770       780       790       800        

           460       470       480       490          500       510
pF1KB3 SGQSKSDKAAALGTKIIDEDGLLNLIRTMPGKKSKYEIAV---ETEMKKESKLERTPQKN
       . ...  :   . . . .:.   ..    : ::.. : :    .:: ::.:: :..:.:.
NP_066 APEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKE
      810       820       830       840       850       860        

                             520       530       540               
pF1KB3 -----VQGKR----------KISPSKKESESKKSRPTSKRDSLAKTIKKE-------TDV
            :. :.          :.  .:.:.:.::. :: .... ::.  ::       :.:
NP_066 APKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEV
      870       880       890       900       910       920        

      550       560       570       580       590       600        
pF1KB3 FWKSLDFKEQVAEETSGDSKARNLADDSSENKVENLLWVDKYKPTSLKTIIGQQGDQSCA
         :  :  .  :.: :  .. .. : .....: :.    ..   :  :   ... :.. .
NP_066 AKKEPD--DAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAK---AKEDDKTLS
      930         940       950       960       970          980   

      610        620       630       640       650       660       
pF1KB3 NKLLR-WLRNWQKSSSEDKKHAKFGKFSGKDDGSSFKAALLSGPPGVGKTTTASLVCQEL
       ..  .   .. .:::: :.: .:  . . .: ... :                       
NP_066 KEPSKPKAEKAEKSSSTDQKDSKPPEKATEDKAAKGK                       
           990      1000      1010      1020                       

       670       680       690       700       710       720       
pF1KB3 GYSYVELNASDTRSKSSLKAIVAESLNNTSIKGFYSNGAASSVSTKHALIMDEVDGMAGN




1147 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 12:14:07 2016 done: Thu Nov  3 12:14:09 2016
 Total Scan time: 14.870 Total Display time:  0.260

Function used was FASTA [36.3.4 Apr, 2011]
Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.com