Result of FASTA (omim) for pF1KB2389
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB2389, 1058 aa
  1>>>pF1KB2389 1058 - 1058 aa - 1058 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.4925+/-0.000422; mu= 20.4643+/- 0.026
 mean_var=68.9510+/-13.826, 0's: 0 Z-trim(110.7): 17  B-trim: 664 in 1/50
 Lambda= 0.154456
 statistics sampled from 19076 (19085) to 19076 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.573), E-opt: 0.2 (0.224), width:  16
 Scan time: 14.600

The best scores are:                                      opt bits E(85289)
NP_056536 (OMIM: 606969) gem-associated protein 4  (1058) 7047 1580.3       0
XP_005256724 (OMIM: 606969) PREDICTED: gem-associa (1062) 7027 1575.8       0
XP_011522212 (OMIM: 606969) PREDICTED: gem-associa (1062) 7027 1575.8       0
XP_016880198 (OMIM: 606969) PREDICTED: gem-associa (1062) 7027 1575.8       0
XP_011522213 (OMIM: 606969) PREDICTED: gem-associa (1062) 7027 1575.8       0
XP_005256727 (OMIM: 606969) PREDICTED: gem-associa (1047) 6967 1562.5       0
XP_011522214 (OMIM: 606969) PREDICTED: gem-associa (1047) 6967 1562.5       0
XP_011522215 (OMIM: 606969) PREDICTED: gem-associa (1047) 6967 1562.5       0


>>NP_056536 (OMIM: 606969) gem-associated protein 4 [Hom  (1058 aa)
 initn: 7047 init1: 7047 opt: 7047  Z-score: 8477.6  bits: 1580.3 E(85289):    0
Smith-Waterman score: 7047; 99.7% identity (99.9% similar) in 1058 aa overlap (1-1058:1-1058)

               10        20        30        40        50        60
pF1KB2 MDLGPLNICEEMTILHGGFLLAEQLFHPKALAELTKSDWERVGRPIVEALREISSAAAHS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MDLGPLNICEEMTILHGGFLLAEQLFHPKALAELTKSDWERVGRPIVEALREISSAAAHS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB2 QPFAWKKKALIIIWAKVLQPHPVTPSDTETRWQEDLFFSVGNMIPTINHTILFELLKSLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 QPFAWKKKALIIIWAKVLQPHPVTPSDTETRWQEDLFFSVGNMIPTINHTILFELLKSLE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB2 ASGLFIQLLMALPTTICHAELERFLEHVTVDTSAEDVAFFLDVWWEVMKHKGHPQDPLLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 ASGLFIQLLMALPTTICHAELERFLEHVTVDTSAEDVAFFLDVWWEVMKHKGHPQDPLLS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB2 QFSAMAHKYLPALDEFPHPPKRLRSDPDACPTMPLLAMLLRGLTQIQSRILGPGRKCCAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 QFSAMAHKYLPALDEFPHPPKRLRSDPDACPTMPLLAMLLRGLTQIQSRILGPGRKCCAL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB2 ANLADMLTVFALTEDDPQEVSATVYLDKLATVISVWNSDTQNPYHQQALAEKVKEAERDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 ANLADMLTVFALTEDDPQEVSATVYLDKLATVISVWNSDTQNPYHQQALAEKVKEAERDV
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB2 SLTSLAKLPSETIFVGCEFLHHLLREWGEELQAVLRSSQGTSYDSYRLCDSLTSFSQNAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 SLTSLAKLPSETIFVGCEFLHHLLREWGEELQAVLRSSQGTSYDSYRLCDSLTSFSQNAT
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB2 LYLNRTSLSKEDRQVVSELAECVRDFLRKTSTVLKNRALEDITASIAMAVIQQKMDRHME
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LYLNRTSLSKEDRQVVSELAECVRDFLRKTSTVLKNRALEDITASIAMAVIQQKMDRHME
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB2 VCYIFASEKKWAFSDEWVACLGSNRALFREPDLVLRLLETVIDVSTADRAIPESQIRQVI
       :::::::::::::::::::::::::::::.::::::::::::::::::::::::::::::
NP_056 VCYIFASEKKWAFSDEWVACLGSNRALFRQPDLVLRLLETVIDVSTADRAIPESQIRQVI
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB2 HLILECYADLSLPGKNKVLAGILRSWGRKGLSEKLLAYVEGFQEDLNTTFNQLTQSASEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 HLILECYADLSLPGKNKVLAGILRSWGRKGLSEKLLAYVEGFQEDLNTTFNQLTQSASEQ
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB2 GLAKAVASVARLVIVHPEVTVKKMCSLAVVNLGTHKFLAQILTAFPALRFVEVQGPNSSA
       :::::::::::::::::::::::::::::::::::::::::::::::::::: :::::::
NP_056 GLAKAVASVARLVIVHPEVTVKKMCSLAVVNLGTHKFLAQILTAFPALRFVEEQGPNSSA
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB2 TFMVSCLKETVWMKFSTPKEEKQFLELLNCLMSPVKPQGIPVAALLEPDEVLKEFVLPFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 TFMVSCLKETVWMKFSTPKEEKQFLELLNCLMSPVKPQGIPVAALLEPDEVLKEFVLPFL
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB2 RLDVEEVDLSLRIFIQTLEANACREEYWLQTCSPFPLLFSLCQLLDRFSKYWQLPKEKRC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 RLDVEEVDLSLRIFIQTLEANACREEYWLQTCSPFPLLFSLCQLLDRFSKYWQLPKEKRC
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB2 LSLDRKDLAIHILELLCEIVSANAETFSPDVWIKSLSWLHRKLEQLDWTVGLRLKSFFEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LSLDRKDLAIHILELLCEIVSANAETFSPDVWIKSLSWLHRKLEQLDWTVGLRLKSFFEG
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB2 HFKCEVPATLFEICKLSEDEWTSQAHPGYGAGTGLLAWMECCCVSSGISERMLSLLVVDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 HFKCEVPATLFEICKLSEDEWTSQAHPGYGAGTGLLAWMECCCVSSGISERMLSLLVVDV
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB2 GNPEEVRLFSKGFLVALVQVMPWCSPQEWQRLHQLTRRLLEKQLLHVPYSLEYIQFVPLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 GNPEEVRLFSKGFLVALVQVMPWCSPQEWQRLHQLTRRLLEKQLLHVPYSLEYIQFVPLL
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB2 NLKPFAQELQLSVLFLRTFQFLCSHSCRNWLPLEGWNHVVKLLCGSLTRLLDSVRAIQAA
       ::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::
NP_056 NLKPFAQELQLSVLFLRTFQFLCSHSCRDWLPLEGWNHVVKLLCGSLTRLLDSVRAIQAA
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KB2 GPWVQGPEQDLTQEALFVYTQVFCHALHIMAMLHPEVCEPLYVLALETLTCYETLSKTNP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 GPWVQGPEQDLTQEALFVYTQVFCHALHIMAMLHPEVCEPLYVLALETLTCYETLSKTNP
              970       980       990      1000      1010      1020

             1030      1040      1050        
pF1KB2 SVSSLLQRAHEQRFLKSIAEGIGPEERRQTLLQKMSSF
       ::::::::::::::::::::::::::::::::::::::
NP_056 SVSSLLQRAHEQRFLKSIAEGIGPEERRQTLLQKMSSF
             1030      1040      1050        

>>XP_005256724 (OMIM: 606969) PREDICTED: gem-associated   (1062 aa)
 initn: 7027 init1: 7027 opt: 7027  Z-score: 8453.5  bits: 1575.8 E(85289):    0
Smith-Waterman score: 7027; 99.7% identity (99.9% similar) in 1055 aa overlap (4-1058:8-1062)

                   10        20        30        40        50      
pF1KB2     MDLGPLNICEEMTILHGGFLLAEQLFHPKALAELTKSDWERVGRPIVEALREISSA
              :::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MFEACSQGPLNICEEMTILHGGFLLAEQLFHPKALAELTKSDWERVGRPIVEALREISSA
               10        20        30        40        50        60

         60        70        80        90       100       110      
pF1KB2 AAHSQPFAWKKKALIIIWAKVLQPHPVTPSDTETRWQEDLFFSVGNMIPTINHTILFELL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AAHSQPFAWKKKALIIIWAKVLQPHPVTPSDTETRWQEDLFFSVGNMIPTINHTILFELL
               70        80        90       100       110       120

        120       130       140       150       160       170      
pF1KB2 KSLEASGLFIQLLMALPTTICHAELERFLEHVTVDTSAEDVAFFLDVWWEVMKHKGHPQD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KSLEASGLFIQLLMALPTTICHAELERFLEHVTVDTSAEDVAFFLDVWWEVMKHKGHPQD
              130       140       150       160       170       180

        180       190       200       210       220       230      
pF1KB2 PLLSQFSAMAHKYLPALDEFPHPPKRLRSDPDACPTMPLLAMLLRGLTQIQSRILGPGRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PLLSQFSAMAHKYLPALDEFPHPPKRLRSDPDACPTMPLLAMLLRGLTQIQSRILGPGRK
              190       200       210       220       230       240

        240       250       260       270       280       290      
pF1KB2 CCALANLADMLTVFALTEDDPQEVSATVYLDKLATVISVWNSDTQNPYHQQALAEKVKEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CCALANLADMLTVFALTEDDPQEVSATVYLDKLATVISVWNSDTQNPYHQQALAEKVKEA
              250       260       270       280       290       300

        300       310       320       330       340       350      
pF1KB2 ERDVSLTSLAKLPSETIFVGCEFLHHLLREWGEELQAVLRSSQGTSYDSYRLCDSLTSFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ERDVSLTSLAKLPSETIFVGCEFLHHLLREWGEELQAVLRSSQGTSYDSYRLCDSLTSFS
              310       320       330       340       350       360

        360       370       380       390       400       410      
pF1KB2 QNATLYLNRTSLSKEDRQVVSELAECVRDFLRKTSTVLKNRALEDITASIAMAVIQQKMD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QNATLYLNRTSLSKEDRQVVSELAECVRDFLRKTSTVLKNRALEDITASIAMAVIQQKMD
              370       380       390       400       410       420

        420       430       440       450       460       470      
pF1KB2 RHMEVCYIFASEKKWAFSDEWVACLGSNRALFREPDLVLRLLETVIDVSTADRAIPESQI
       :::::::::::::::::::::::::::::::::.::::::::::::::::::::::::::
XP_005 RHMEVCYIFASEKKWAFSDEWVACLGSNRALFRQPDLVLRLLETVIDVSTADRAIPESQI
              430       440       450       460       470       480

        480       490       500       510       520       530      
pF1KB2 RQVIHLILECYADLSLPGKNKVLAGILRSWGRKGLSEKLLAYVEGFQEDLNTTFNQLTQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RQVIHLILECYADLSLPGKNKVLAGILRSWGRKGLSEKLLAYVEGFQEDLNTTFNQLTQS
              490       500       510       520       530       540

        540       550       560       570       580       590      
pF1KB2 ASEQGLAKAVASVARLVIVHPEVTVKKMCSLAVVNLGTHKFLAQILTAFPALRFVEVQGP
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::: :::
XP_005 ASEQGLAKAVASVARLVIVHPEVTVKKMCSLAVVNLGTHKFLAQILTAFPALRFVEEQGP
              550       560       570       580       590       600

        600       610       620       630       640       650      
pF1KB2 NSSATFMVSCLKETVWMKFSTPKEEKQFLELLNCLMSPVKPQGIPVAALLEPDEVLKEFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NSSATFMVSCLKETVWMKFSTPKEEKQFLELLNCLMSPVKPQGIPVAALLEPDEVLKEFV
              610       620       630       640       650       660

        660       670       680       690       700       710      
pF1KB2 LPFLRLDVEEVDLSLRIFIQTLEANACREEYWLQTCSPFPLLFSLCQLLDRFSKYWQLPK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LPFLRLDVEEVDLSLRIFIQTLEANACREEYWLQTCSPFPLLFSLCQLLDRFSKYWQLPK
              670       680       690       700       710       720

        720       730       740       750       760       770      
pF1KB2 EKRCLSLDRKDLAIHILELLCEIVSANAETFSPDVWIKSLSWLHRKLEQLDWTVGLRLKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EKRCLSLDRKDLAIHILELLCEIVSANAETFSPDVWIKSLSWLHRKLEQLDWTVGLRLKS
              730       740       750       760       770       780

        780       790       800       810       820       830      
pF1KB2 FFEGHFKCEVPATLFEICKLSEDEWTSQAHPGYGAGTGLLAWMECCCVSSGISERMLSLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FFEGHFKCEVPATLFEICKLSEDEWTSQAHPGYGAGTGLLAWMECCCVSSGISERMLSLL
              790       800       810       820       830       840

        840       850       860       870       880       890      
pF1KB2 VVDVGNPEEVRLFSKGFLVALVQVMPWCSPQEWQRLHQLTRRLLEKQLLHVPYSLEYIQF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VVDVGNPEEVRLFSKGFLVALVQVMPWCSPQEWQRLHQLTRRLLEKQLLHVPYSLEYIQF
              850       860       870       880       890       900

        900       910       920       930       940       950      
pF1KB2 VPLLNLKPFAQELQLSVLFLRTFQFLCSHSCRNWLPLEGWNHVVKLLCGSLTRLLDSVRA
       ::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::
XP_005 VPLLNLKPFAQELQLSVLFLRTFQFLCSHSCRDWLPLEGWNHVVKLLCGSLTRLLDSVRA
              910       920       930       940       950       960

        960       970       980       990      1000      1010      
pF1KB2 IQAAGPWVQGPEQDLTQEALFVYTQVFCHALHIMAMLHPEVCEPLYVLALETLTCYETLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IQAAGPWVQGPEQDLTQEALFVYTQVFCHALHIMAMLHPEVCEPLYVLALETLTCYETLS
              970       980       990      1000      1010      1020

       1020      1030      1040      1050        
pF1KB2 KTNPSVSSLLQRAHEQRFLKSIAEGIGPEERRQTLLQKMSSF
       ::::::::::::::::::::::::::::::::::::::::::
XP_005 KTNPSVSSLLQRAHEQRFLKSIAEGIGPEERRQTLLQKMSSF
             1030      1040      1050      1060  

>>XP_011522212 (OMIM: 606969) PREDICTED: gem-associated   (1062 aa)
 initn: 7027 init1: 7027 opt: 7027  Z-score: 8453.5  bits: 1575.8 E(85289):    0
Smith-Waterman score: 7027; 99.7% identity (99.9% similar) in 1055 aa overlap (4-1058:8-1062)

                   10        20        30        40        50      
pF1KB2     MDLGPLNICEEMTILHGGFLLAEQLFHPKALAELTKSDWERVGRPIVEALREISSA
              :::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MFEACSQGPLNICEEMTILHGGFLLAEQLFHPKALAELTKSDWERVGRPIVEALREISSA
               10        20        30        40        50        60

         60        70        80        90       100       110      
pF1KB2 AAHSQPFAWKKKALIIIWAKVLQPHPVTPSDTETRWQEDLFFSVGNMIPTINHTILFELL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAHSQPFAWKKKALIIIWAKVLQPHPVTPSDTETRWQEDLFFSVGNMIPTINHTILFELL
               70        80        90       100       110       120

        120       130       140       150       160       170      
pF1KB2 KSLEASGLFIQLLMALPTTICHAELERFLEHVTVDTSAEDVAFFLDVWWEVMKHKGHPQD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSLEASGLFIQLLMALPTTICHAELERFLEHVTVDTSAEDVAFFLDVWWEVMKHKGHPQD
              130       140       150       160       170       180

        180       190       200       210       220       230      
pF1KB2 PLLSQFSAMAHKYLPALDEFPHPPKRLRSDPDACPTMPLLAMLLRGLTQIQSRILGPGRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLLSQFSAMAHKYLPALDEFPHPPKRLRSDPDACPTMPLLAMLLRGLTQIQSRILGPGRK
              190       200       210       220       230       240

        240       250       260       270       280       290      
pF1KB2 CCALANLADMLTVFALTEDDPQEVSATVYLDKLATVISVWNSDTQNPYHQQALAEKVKEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CCALANLADMLTVFALTEDDPQEVSATVYLDKLATVISVWNSDTQNPYHQQALAEKVKEA
              250       260       270       280       290       300

        300       310       320       330       340       350      
pF1KB2 ERDVSLTSLAKLPSETIFVGCEFLHHLLREWGEELQAVLRSSQGTSYDSYRLCDSLTSFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERDVSLTSLAKLPSETIFVGCEFLHHLLREWGEELQAVLRSSQGTSYDSYRLCDSLTSFS
              310       320       330       340       350       360

        360       370       380       390       400       410      
pF1KB2 QNATLYLNRTSLSKEDRQVVSELAECVRDFLRKTSTVLKNRALEDITASIAMAVIQQKMD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QNATLYLNRTSLSKEDRQVVSELAECVRDFLRKTSTVLKNRALEDITASIAMAVIQQKMD
              370       380       390       400       410       420

        420       430       440       450       460       470      
pF1KB2 RHMEVCYIFASEKKWAFSDEWVACLGSNRALFREPDLVLRLLETVIDVSTADRAIPESQI
       :::::::::::::::::::::::::::::::::.::::::::::::::::::::::::::
XP_011 RHMEVCYIFASEKKWAFSDEWVACLGSNRALFRQPDLVLRLLETVIDVSTADRAIPESQI
              430       440       450       460       470       480

        480       490       500       510       520       530      
pF1KB2 RQVIHLILECYADLSLPGKNKVLAGILRSWGRKGLSEKLLAYVEGFQEDLNTTFNQLTQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RQVIHLILECYADLSLPGKNKVLAGILRSWGRKGLSEKLLAYVEGFQEDLNTTFNQLTQS
              490       500       510       520       530       540

        540       550       560       570       580       590      
pF1KB2 ASEQGLAKAVASVARLVIVHPEVTVKKMCSLAVVNLGTHKFLAQILTAFPALRFVEVQGP
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::: :::
XP_011 ASEQGLAKAVASVARLVIVHPEVTVKKMCSLAVVNLGTHKFLAQILTAFPALRFVEEQGP
              550       560       570       580       590       600

        600       610       620       630       640       650      
pF1KB2 NSSATFMVSCLKETVWMKFSTPKEEKQFLELLNCLMSPVKPQGIPVAALLEPDEVLKEFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSSATFMVSCLKETVWMKFSTPKEEKQFLELLNCLMSPVKPQGIPVAALLEPDEVLKEFV
              610       620       630       640       650       660

        660       670       680       690       700       710      
pF1KB2 LPFLRLDVEEVDLSLRIFIQTLEANACREEYWLQTCSPFPLLFSLCQLLDRFSKYWQLPK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPFLRLDVEEVDLSLRIFIQTLEANACREEYWLQTCSPFPLLFSLCQLLDRFSKYWQLPK
              670       680       690       700       710       720

        720       730       740       750       760       770      
pF1KB2 EKRCLSLDRKDLAIHILELLCEIVSANAETFSPDVWIKSLSWLHRKLEQLDWTVGLRLKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKRCLSLDRKDLAIHILELLCEIVSANAETFSPDVWIKSLSWLHRKLEQLDWTVGLRLKS
              730       740       750       760       770       780

        780       790       800       810       820       830      
pF1KB2 FFEGHFKCEVPATLFEICKLSEDEWTSQAHPGYGAGTGLLAWMECCCVSSGISERMLSLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FFEGHFKCEVPATLFEICKLSEDEWTSQAHPGYGAGTGLLAWMECCCVSSGISERMLSLL
              790       800       810       820       830       840

        840       850       860       870       880       890      
pF1KB2 VVDVGNPEEVRLFSKGFLVALVQVMPWCSPQEWQRLHQLTRRLLEKQLLHVPYSLEYIQF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVDVGNPEEVRLFSKGFLVALVQVMPWCSPQEWQRLHQLTRRLLEKQLLHVPYSLEYIQF
              850       860       870       880       890       900

        900       910       920       930       940       950      
pF1KB2 VPLLNLKPFAQELQLSVLFLRTFQFLCSHSCRNWLPLEGWNHVVKLLCGSLTRLLDSVRA
       ::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::
XP_011 VPLLNLKPFAQELQLSVLFLRTFQFLCSHSCRDWLPLEGWNHVVKLLCGSLTRLLDSVRA
              910       920       930       940       950       960

        960       970       980       990      1000      1010      
pF1KB2 IQAAGPWVQGPEQDLTQEALFVYTQVFCHALHIMAMLHPEVCEPLYVLALETLTCYETLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IQAAGPWVQGPEQDLTQEALFVYTQVFCHALHIMAMLHPEVCEPLYVLALETLTCYETLS
              970       980       990      1000      1010      1020

       1020      1030      1040      1050        
pF1KB2 KTNPSVSSLLQRAHEQRFLKSIAEGIGPEERRQTLLQKMSSF
       ::::::::::::::::::::::::::::::::::::::::::
XP_011 KTNPSVSSLLQRAHEQRFLKSIAEGIGPEERRQTLLQKMSSF
             1030      1040      1050      1060  

>>XP_016880198 (OMIM: 606969) PREDICTED: gem-associated   (1062 aa)
 initn: 7027 init1: 7027 opt: 7027  Z-score: 8453.5  bits: 1575.8 E(85289):    0
Smith-Waterman score: 7027; 99.7% identity (99.9% similar) in 1055 aa overlap (4-1058:8-1062)

                   10        20        30        40        50      
pF1KB2     MDLGPLNICEEMTILHGGFLLAEQLFHPKALAELTKSDWERVGRPIVEALREISSA
              :::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MFEACSQGPLNICEEMTILHGGFLLAEQLFHPKALAELTKSDWERVGRPIVEALREISSA
               10        20        30        40        50        60

         60        70        80        90       100       110      
pF1KB2 AAHSQPFAWKKKALIIIWAKVLQPHPVTPSDTETRWQEDLFFSVGNMIPTINHTILFELL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAHSQPFAWKKKALIIIWAKVLQPHPVTPSDTETRWQEDLFFSVGNMIPTINHTILFELL
               70        80        90       100       110       120

        120       130       140       150       160       170      
pF1KB2 KSLEASGLFIQLLMALPTTICHAELERFLEHVTVDTSAEDVAFFLDVWWEVMKHKGHPQD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSLEASGLFIQLLMALPTTICHAELERFLEHVTVDTSAEDVAFFLDVWWEVMKHKGHPQD
              130       140       150       160       170       180

        180       190       200       210       220       230      
pF1KB2 PLLSQFSAMAHKYLPALDEFPHPPKRLRSDPDACPTMPLLAMLLRGLTQIQSRILGPGRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLLSQFSAMAHKYLPALDEFPHPPKRLRSDPDACPTMPLLAMLLRGLTQIQSRILGPGRK
              190       200       210       220       230       240

        240       250       260       270       280       290      
pF1KB2 CCALANLADMLTVFALTEDDPQEVSATVYLDKLATVISVWNSDTQNPYHQQALAEKVKEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CCALANLADMLTVFALTEDDPQEVSATVYLDKLATVISVWNSDTQNPYHQQALAEKVKEA
              250       260       270       280       290       300

        300       310       320       330       340       350      
pF1KB2 ERDVSLTSLAKLPSETIFVGCEFLHHLLREWGEELQAVLRSSQGTSYDSYRLCDSLTSFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERDVSLTSLAKLPSETIFVGCEFLHHLLREWGEELQAVLRSSQGTSYDSYRLCDSLTSFS
              310       320       330       340       350       360

        360       370       380       390       400       410      
pF1KB2 QNATLYLNRTSLSKEDRQVVSELAECVRDFLRKTSTVLKNRALEDITASIAMAVIQQKMD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QNATLYLNRTSLSKEDRQVVSELAECVRDFLRKTSTVLKNRALEDITASIAMAVIQQKMD
              370       380       390       400       410       420

        420       430       440       450       460       470      
pF1KB2 RHMEVCYIFASEKKWAFSDEWVACLGSNRALFREPDLVLRLLETVIDVSTADRAIPESQI
       :::::::::::::::::::::::::::::::::.::::::::::::::::::::::::::
XP_016 RHMEVCYIFASEKKWAFSDEWVACLGSNRALFRQPDLVLRLLETVIDVSTADRAIPESQI
              430       440       450       460       470       480

        480       490       500       510       520       530      
pF1KB2 RQVIHLILECYADLSLPGKNKVLAGILRSWGRKGLSEKLLAYVEGFQEDLNTTFNQLTQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQVIHLILECYADLSLPGKNKVLAGILRSWGRKGLSEKLLAYVEGFQEDLNTTFNQLTQS
              490       500       510       520       530       540

        540       550       560       570       580       590      
pF1KB2 ASEQGLAKAVASVARLVIVHPEVTVKKMCSLAVVNLGTHKFLAQILTAFPALRFVEVQGP
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::: :::
XP_016 ASEQGLAKAVASVARLVIVHPEVTVKKMCSLAVVNLGTHKFLAQILTAFPALRFVEEQGP
              550       560       570       580       590       600

        600       610       620       630       640       650      
pF1KB2 NSSATFMVSCLKETVWMKFSTPKEEKQFLELLNCLMSPVKPQGIPVAALLEPDEVLKEFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSSATFMVSCLKETVWMKFSTPKEEKQFLELLNCLMSPVKPQGIPVAALLEPDEVLKEFV
              610       620       630       640       650       660

        660       670       680       690       700       710      
pF1KB2 LPFLRLDVEEVDLSLRIFIQTLEANACREEYWLQTCSPFPLLFSLCQLLDRFSKYWQLPK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPFLRLDVEEVDLSLRIFIQTLEANACREEYWLQTCSPFPLLFSLCQLLDRFSKYWQLPK
              670       680       690       700       710       720

        720       730       740       750       760       770      
pF1KB2 EKRCLSLDRKDLAIHILELLCEIVSANAETFSPDVWIKSLSWLHRKLEQLDWTVGLRLKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKRCLSLDRKDLAIHILELLCEIVSANAETFSPDVWIKSLSWLHRKLEQLDWTVGLRLKS
              730       740       750       760       770       780

        780       790       800       810       820       830      
pF1KB2 FFEGHFKCEVPATLFEICKLSEDEWTSQAHPGYGAGTGLLAWMECCCVSSGISERMLSLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FFEGHFKCEVPATLFEICKLSEDEWTSQAHPGYGAGTGLLAWMECCCVSSGISERMLSLL
              790       800       810       820       830       840

        840       850       860       870       880       890      
pF1KB2 VVDVGNPEEVRLFSKGFLVALVQVMPWCSPQEWQRLHQLTRRLLEKQLLHVPYSLEYIQF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVDVGNPEEVRLFSKGFLVALVQVMPWCSPQEWQRLHQLTRRLLEKQLLHVPYSLEYIQF
              850       860       870       880       890       900

        900       910       920       930       940       950      
pF1KB2 VPLLNLKPFAQELQLSVLFLRTFQFLCSHSCRNWLPLEGWNHVVKLLCGSLTRLLDSVRA
       ::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::
XP_016 VPLLNLKPFAQELQLSVLFLRTFQFLCSHSCRDWLPLEGWNHVVKLLCGSLTRLLDSVRA
              910       920       930       940       950       960

        960       970       980       990      1000      1010      
pF1KB2 IQAAGPWVQGPEQDLTQEALFVYTQVFCHALHIMAMLHPEVCEPLYVLALETLTCYETLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IQAAGPWVQGPEQDLTQEALFVYTQVFCHALHIMAMLHPEVCEPLYVLALETLTCYETLS
              970       980       990      1000      1010      1020

       1020      1030      1040      1050        
pF1KB2 KTNPSVSSLLQRAHEQRFLKSIAEGIGPEERRQTLLQKMSSF
       ::::::::::::::::::::::::::::::::::::::::::
XP_016 KTNPSVSSLLQRAHEQRFLKSIAEGIGPEERRQTLLQKMSSF
             1030      1040      1050      1060  

>>XP_011522213 (OMIM: 606969) PREDICTED: gem-associated   (1062 aa)
 initn: 7027 init1: 7027 opt: 7027  Z-score: 8453.5  bits: 1575.8 E(85289):    0
Smith-Waterman score: 7027; 99.7% identity (99.9% similar) in 1055 aa overlap (4-1058:8-1062)

                   10        20        30        40        50      
pF1KB2     MDLGPLNICEEMTILHGGFLLAEQLFHPKALAELTKSDWERVGRPIVEALREISSA
              :::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MFEACSQGPLNICEEMTILHGGFLLAEQLFHPKALAELTKSDWERVGRPIVEALREISSA
               10        20        30        40        50        60

         60        70        80        90       100       110      
pF1KB2 AAHSQPFAWKKKALIIIWAKVLQPHPVTPSDTETRWQEDLFFSVGNMIPTINHTILFELL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAHSQPFAWKKKALIIIWAKVLQPHPVTPSDTETRWQEDLFFSVGNMIPTINHTILFELL
               70        80        90       100       110       120

        120       130       140       150       160       170      
pF1KB2 KSLEASGLFIQLLMALPTTICHAELERFLEHVTVDTSAEDVAFFLDVWWEVMKHKGHPQD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSLEASGLFIQLLMALPTTICHAELERFLEHVTVDTSAEDVAFFLDVWWEVMKHKGHPQD
              130       140       150       160       170       180

        180       190       200       210       220       230      
pF1KB2 PLLSQFSAMAHKYLPALDEFPHPPKRLRSDPDACPTMPLLAMLLRGLTQIQSRILGPGRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLLSQFSAMAHKYLPALDEFPHPPKRLRSDPDACPTMPLLAMLLRGLTQIQSRILGPGRK
              190       200       210       220       230       240

        240       250       260       270       280       290      
pF1KB2 CCALANLADMLTVFALTEDDPQEVSATVYLDKLATVISVWNSDTQNPYHQQALAEKVKEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CCALANLADMLTVFALTEDDPQEVSATVYLDKLATVISVWNSDTQNPYHQQALAEKVKEA
              250       260       270       280       290       300

        300       310       320       330       340       350      
pF1KB2 ERDVSLTSLAKLPSETIFVGCEFLHHLLREWGEELQAVLRSSQGTSYDSYRLCDSLTSFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERDVSLTSLAKLPSETIFVGCEFLHHLLREWGEELQAVLRSSQGTSYDSYRLCDSLTSFS
              310       320       330       340       350       360

        360       370       380       390       400       410      
pF1KB2 QNATLYLNRTSLSKEDRQVVSELAECVRDFLRKTSTVLKNRALEDITASIAMAVIQQKMD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QNATLYLNRTSLSKEDRQVVSELAECVRDFLRKTSTVLKNRALEDITASIAMAVIQQKMD
              370       380       390       400       410       420

        420       430       440       450       460       470      
pF1KB2 RHMEVCYIFASEKKWAFSDEWVACLGSNRALFREPDLVLRLLETVIDVSTADRAIPESQI
       :::::::::::::::::::::::::::::::::.::::::::::::::::::::::::::
XP_011 RHMEVCYIFASEKKWAFSDEWVACLGSNRALFRQPDLVLRLLETVIDVSTADRAIPESQI
              430       440       450       460       470       480

        480       490       500       510       520       530      
pF1KB2 RQVIHLILECYADLSLPGKNKVLAGILRSWGRKGLSEKLLAYVEGFQEDLNTTFNQLTQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RQVIHLILECYADLSLPGKNKVLAGILRSWGRKGLSEKLLAYVEGFQEDLNTTFNQLTQS
              490       500       510       520       530       540

        540       550       560       570       580       590      
pF1KB2 ASEQGLAKAVASVARLVIVHPEVTVKKMCSLAVVNLGTHKFLAQILTAFPALRFVEVQGP
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::: :::
XP_011 ASEQGLAKAVASVARLVIVHPEVTVKKMCSLAVVNLGTHKFLAQILTAFPALRFVEEQGP
              550       560       570       580       590       600

        600       610       620       630       640       650      
pF1KB2 NSSATFMVSCLKETVWMKFSTPKEEKQFLELLNCLMSPVKPQGIPVAALLEPDEVLKEFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSSATFMVSCLKETVWMKFSTPKEEKQFLELLNCLMSPVKPQGIPVAALLEPDEVLKEFV
              610       620       630       640       650       660

        660       670       680       690       700       710      
pF1KB2 LPFLRLDVEEVDLSLRIFIQTLEANACREEYWLQTCSPFPLLFSLCQLLDRFSKYWQLPK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPFLRLDVEEVDLSLRIFIQTLEANACREEYWLQTCSPFPLLFSLCQLLDRFSKYWQLPK
              670       680       690       700       710       720

        720       730       740       750       760       770      
pF1KB2 EKRCLSLDRKDLAIHILELLCEIVSANAETFSPDVWIKSLSWLHRKLEQLDWTVGLRLKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKRCLSLDRKDLAIHILELLCEIVSANAETFSPDVWIKSLSWLHRKLEQLDWTVGLRLKS
              730       740       750       760       770       780

        780       790       800       810       820       830      
pF1KB2 FFEGHFKCEVPATLFEICKLSEDEWTSQAHPGYGAGTGLLAWMECCCVSSGISERMLSLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FFEGHFKCEVPATLFEICKLSEDEWTSQAHPGYGAGTGLLAWMECCCVSSGISERMLSLL
              790       800       810       820       830       840

        840       850       860       870       880       890      
pF1KB2 VVDVGNPEEVRLFSKGFLVALVQVMPWCSPQEWQRLHQLTRRLLEKQLLHVPYSLEYIQF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVDVGNPEEVRLFSKGFLVALVQVMPWCSPQEWQRLHQLTRRLLEKQLLHVPYSLEYIQF
              850       860       870       880       890       900

        900       910       920       930       940       950      
pF1KB2 VPLLNLKPFAQELQLSVLFLRTFQFLCSHSCRNWLPLEGWNHVVKLLCGSLTRLLDSVRA
       ::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::
XP_011 VPLLNLKPFAQELQLSVLFLRTFQFLCSHSCRDWLPLEGWNHVVKLLCGSLTRLLDSVRA
              910       920       930       940       950       960

        960       970       980       990      1000      1010      
pF1KB2 IQAAGPWVQGPEQDLTQEALFVYTQVFCHALHIMAMLHPEVCEPLYVLALETLTCYETLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IQAAGPWVQGPEQDLTQEALFVYTQVFCHALHIMAMLHPEVCEPLYVLALETLTCYETLS
              970       980       990      1000      1010      1020

       1020      1030      1040      1050        
pF1KB2 KTNPSVSSLLQRAHEQRFLKSIAEGIGPEERRQTLLQKMSSF
       ::::::::::::::::::::::::::::::::::::::::::
XP_011 KTNPSVSSLLQRAHEQRFLKSIAEGIGPEERRQTLLQKMSSF
             1030      1040      1050      1060  

>>XP_005256727 (OMIM: 606969) PREDICTED: gem-associated   (1047 aa)
 initn: 6967 init1: 6967 opt: 6967  Z-score: 8381.3  bits: 1562.5 E(85289):    0
Smith-Waterman score: 6967; 99.7% identity (99.9% similar) in 1047 aa overlap (12-1058:1-1047)

               10        20        30        40        50        60
pF1KB2 MDLGPLNICEEMTILHGGFLLAEQLFHPKALAELTKSDWERVGRPIVEALREISSAAAHS
                  :::::::::::::::::::::::::::::::::::::::::::::::::
XP_005            MTILHGGFLLAEQLFHPKALAELTKSDWERVGRPIVEALREISSAAAHS
                          10        20        30        40         

               70        80        90       100       110       120
pF1KB2 QPFAWKKKALIIIWAKVLQPHPVTPSDTETRWQEDLFFSVGNMIPTINHTILFELLKSLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QPFAWKKKALIIIWAKVLQPHPVTPSDTETRWQEDLFFSVGNMIPTINHTILFELLKSLE
      50        60        70        80        90       100         

              130       140       150       160       170       180
pF1KB2 ASGLFIQLLMALPTTICHAELERFLEHVTVDTSAEDVAFFLDVWWEVMKHKGHPQDPLLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ASGLFIQLLMALPTTICHAELERFLEHVTVDTSAEDVAFFLDVWWEVMKHKGHPQDPLLS
     110       120       130       140       150       160         

              190       200       210       220       230       240
pF1KB2 QFSAMAHKYLPALDEFPHPPKRLRSDPDACPTMPLLAMLLRGLTQIQSRILGPGRKCCAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QFSAMAHKYLPALDEFPHPPKRLRSDPDACPTMPLLAMLLRGLTQIQSRILGPGRKCCAL
     170       180       190       200       210       220         

              250       260       270       280       290       300
pF1KB2 ANLADMLTVFALTEDDPQEVSATVYLDKLATVISVWNSDTQNPYHQQALAEKVKEAERDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ANLADMLTVFALTEDDPQEVSATVYLDKLATVISVWNSDTQNPYHQQALAEKVKEAERDV
     230       240       250       260       270       280         

              310       320       330       340       350       360
pF1KB2 SLTSLAKLPSETIFVGCEFLHHLLREWGEELQAVLRSSQGTSYDSYRLCDSLTSFSQNAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLTSLAKLPSETIFVGCEFLHHLLREWGEELQAVLRSSQGTSYDSYRLCDSLTSFSQNAT
     290       300       310       320       330       340         

              370       380       390       400       410       420
pF1KB2 LYLNRTSLSKEDRQVVSELAECVRDFLRKTSTVLKNRALEDITASIAMAVIQQKMDRHME
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LYLNRTSLSKEDRQVVSELAECVRDFLRKTSTVLKNRALEDITASIAMAVIQQKMDRHME
     350       360       370       380       390       400         

              430       440       450       460       470       480
pF1KB2 VCYIFASEKKWAFSDEWVACLGSNRALFREPDLVLRLLETVIDVSTADRAIPESQIRQVI
       :::::::::::::::::::::::::::::.::::::::::::::::::::::::::::::
XP_005 VCYIFASEKKWAFSDEWVACLGSNRALFRQPDLVLRLLETVIDVSTADRAIPESQIRQVI
     410       420       430       440       450       460         

              490       500       510       520       530       540
pF1KB2 HLILECYADLSLPGKNKVLAGILRSWGRKGLSEKLLAYVEGFQEDLNTTFNQLTQSASEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HLILECYADLSLPGKNKVLAGILRSWGRKGLSEKLLAYVEGFQEDLNTTFNQLTQSASEQ
     470       480       490       500       510       520         

              550       560       570       580       590       600
pF1KB2 GLAKAVASVARLVIVHPEVTVKKMCSLAVVNLGTHKFLAQILTAFPALRFVEVQGPNSSA
       :::::::::::::::::::::::::::::::::::::::::::::::::::: :::::::
XP_005 GLAKAVASVARLVIVHPEVTVKKMCSLAVVNLGTHKFLAQILTAFPALRFVEEQGPNSSA
     530       540       550       560       570       580         

              610       620       630       640       650       660
pF1KB2 TFMVSCLKETVWMKFSTPKEEKQFLELLNCLMSPVKPQGIPVAALLEPDEVLKEFVLPFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TFMVSCLKETVWMKFSTPKEEKQFLELLNCLMSPVKPQGIPVAALLEPDEVLKEFVLPFL
     590       600       610       620       630       640         

              670       680       690       700       710       720
pF1KB2 RLDVEEVDLSLRIFIQTLEANACREEYWLQTCSPFPLLFSLCQLLDRFSKYWQLPKEKRC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RLDVEEVDLSLRIFIQTLEANACREEYWLQTCSPFPLLFSLCQLLDRFSKYWQLPKEKRC
     650       660       670       680       690       700         

              730       740       750       760       770       780
pF1KB2 LSLDRKDLAIHILELLCEIVSANAETFSPDVWIKSLSWLHRKLEQLDWTVGLRLKSFFEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LSLDRKDLAIHILELLCEIVSANAETFSPDVWIKSLSWLHRKLEQLDWTVGLRLKSFFEG
     710       720       730       740       750       760         

              790       800       810       820       830       840
pF1KB2 HFKCEVPATLFEICKLSEDEWTSQAHPGYGAGTGLLAWMECCCVSSGISERMLSLLVVDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HFKCEVPATLFEICKLSEDEWTSQAHPGYGAGTGLLAWMECCCVSSGISERMLSLLVVDV
     770       780       790       800       810       820         

              850       860       870       880       890       900
pF1KB2 GNPEEVRLFSKGFLVALVQVMPWCSPQEWQRLHQLTRRLLEKQLLHVPYSLEYIQFVPLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GNPEEVRLFSKGFLVALVQVMPWCSPQEWQRLHQLTRRLLEKQLLHVPYSLEYIQFVPLL
     830       840       850       860       870       880         

              910       920       930       940       950       960
pF1KB2 NLKPFAQELQLSVLFLRTFQFLCSHSCRNWLPLEGWNHVVKLLCGSLTRLLDSVRAIQAA
       ::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::
XP_005 NLKPFAQELQLSVLFLRTFQFLCSHSCRDWLPLEGWNHVVKLLCGSLTRLLDSVRAIQAA
     890       900       910       920       930       940         

              970       980       990      1000      1010      1020
pF1KB2 GPWVQGPEQDLTQEALFVYTQVFCHALHIMAMLHPEVCEPLYVLALETLTCYETLSKTNP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GPWVQGPEQDLTQEALFVYTQVFCHALHIMAMLHPEVCEPLYVLALETLTCYETLSKTNP
     950       960       970       980       990      1000         

             1030      1040      1050        
pF1KB2 SVSSLLQRAHEQRFLKSIAEGIGPEERRQTLLQKMSSF
       ::::::::::::::::::::::::::::::::::::::
XP_005 SVSSLLQRAHEQRFLKSIAEGIGPEERRQTLLQKMSSF
    1010      1020      1030      1040       

>>XP_011522214 (OMIM: 606969) PREDICTED: gem-associated   (1047 aa)
 initn: 6967 init1: 6967 opt: 6967  Z-score: 8381.3  bits: 1562.5 E(85289):    0
Smith-Waterman score: 6967; 99.7% identity (99.9% similar) in 1047 aa overlap (12-1058:1-1047)

               10        20        30        40        50        60
pF1KB2 MDLGPLNICEEMTILHGGFLLAEQLFHPKALAELTKSDWERVGRPIVEALREISSAAAHS
                  :::::::::::::::::::::::::::::::::::::::::::::::::
XP_011            MTILHGGFLLAEQLFHPKALAELTKSDWERVGRPIVEALREISSAAAHS
                          10        20        30        40         

               70        80        90       100       110       120
pF1KB2 QPFAWKKKALIIIWAKVLQPHPVTPSDTETRWQEDLFFSVGNMIPTINHTILFELLKSLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QPFAWKKKALIIIWAKVLQPHPVTPSDTETRWQEDLFFSVGNMIPTINHTILFELLKSLE
      50        60        70        80        90       100         

              130       140       150       160       170       180
pF1KB2 ASGLFIQLLMALPTTICHAELERFLEHVTVDTSAEDVAFFLDVWWEVMKHKGHPQDPLLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASGLFIQLLMALPTTICHAELERFLEHVTVDTSAEDVAFFLDVWWEVMKHKGHPQDPLLS
     110       120       130       140       150       160         

              190       200       210       220       230       240
pF1KB2 QFSAMAHKYLPALDEFPHPPKRLRSDPDACPTMPLLAMLLRGLTQIQSRILGPGRKCCAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QFSAMAHKYLPALDEFPHPPKRLRSDPDACPTMPLLAMLLRGLTQIQSRILGPGRKCCAL
     170       180       190       200       210       220         

              250       260       270       280       290       300
pF1KB2 ANLADMLTVFALTEDDPQEVSATVYLDKLATVISVWNSDTQNPYHQQALAEKVKEAERDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ANLADMLTVFALTEDDPQEVSATVYLDKLATVISVWNSDTQNPYHQQALAEKVKEAERDV
     230       240       250       260       270       280         

              310       320       330       340       350       360
pF1KB2 SLTSLAKLPSETIFVGCEFLHHLLREWGEELQAVLRSSQGTSYDSYRLCDSLTSFSQNAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLTSLAKLPSETIFVGCEFLHHLLREWGEELQAVLRSSQGTSYDSYRLCDSLTSFSQNAT
     290       300       310       320       330       340         

              370       380       390       400       410       420
pF1KB2 LYLNRTSLSKEDRQVVSELAECVRDFLRKTSTVLKNRALEDITASIAMAVIQQKMDRHME
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LYLNRTSLSKEDRQVVSELAECVRDFLRKTSTVLKNRALEDITASIAMAVIQQKMDRHME
     350       360       370       380       390       400         

              430       440       450       460       470       480
pF1KB2 VCYIFASEKKWAFSDEWVACLGSNRALFREPDLVLRLLETVIDVSTADRAIPESQIRQVI
       :::::::::::::::::::::::::::::.::::::::::::::::::::::::::::::
XP_011 VCYIFASEKKWAFSDEWVACLGSNRALFRQPDLVLRLLETVIDVSTADRAIPESQIRQVI
     410       420       430       440       450       460         

              490       500       510       520       530       540
pF1KB2 HLILECYADLSLPGKNKVLAGILRSWGRKGLSEKLLAYVEGFQEDLNTTFNQLTQSASEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HLILECYADLSLPGKNKVLAGILRSWGRKGLSEKLLAYVEGFQEDLNTTFNQLTQSASEQ
     470       480       490       500       510       520         

              550       560       570       580       590       600
pF1KB2 GLAKAVASVARLVIVHPEVTVKKMCSLAVVNLGTHKFLAQILTAFPALRFVEVQGPNSSA
       :::::::::::::::::::::::::::::::::::::::::::::::::::: :::::::
XP_011 GLAKAVASVARLVIVHPEVTVKKMCSLAVVNLGTHKFLAQILTAFPALRFVEEQGPNSSA
     530       540       550       560       570       580         

              610       620       630       640       650       660
pF1KB2 TFMVSCLKETVWMKFSTPKEEKQFLELLNCLMSPVKPQGIPVAALLEPDEVLKEFVLPFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TFMVSCLKETVWMKFSTPKEEKQFLELLNCLMSPVKPQGIPVAALLEPDEVLKEFVLPFL
     590       600       610       620       630       640         

              670       680       690       700       710       720
pF1KB2 RLDVEEVDLSLRIFIQTLEANACREEYWLQTCSPFPLLFSLCQLLDRFSKYWQLPKEKRC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLDVEEVDLSLRIFIQTLEANACREEYWLQTCSPFPLLFSLCQLLDRFSKYWQLPKEKRC
     650       660       670       680       690       700         

              730       740       750       760       770       780
pF1KB2 LSLDRKDLAIHILELLCEIVSANAETFSPDVWIKSLSWLHRKLEQLDWTVGLRLKSFFEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSLDRKDLAIHILELLCEIVSANAETFSPDVWIKSLSWLHRKLEQLDWTVGLRLKSFFEG
     710       720       730       740       750       760         

              790       800       810       820       830       840
pF1KB2 HFKCEVPATLFEICKLSEDEWTSQAHPGYGAGTGLLAWMECCCVSSGISERMLSLLVVDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HFKCEVPATLFEICKLSEDEWTSQAHPGYGAGTGLLAWMECCCVSSGISERMLSLLVVDV
     770       780       790       800       810       820         

              850       860       870       880       890       900
pF1KB2 GNPEEVRLFSKGFLVALVQVMPWCSPQEWQRLHQLTRRLLEKQLLHVPYSLEYIQFVPLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GNPEEVRLFSKGFLVALVQVMPWCSPQEWQRLHQLTRRLLEKQLLHVPYSLEYIQFVPLL
     830       840       850       860       870       880         

              910       920       930       940       950       960
pF1KB2 NLKPFAQELQLSVLFLRTFQFLCSHSCRNWLPLEGWNHVVKLLCGSLTRLLDSVRAIQAA
       ::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::
XP_011 NLKPFAQELQLSVLFLRTFQFLCSHSCRDWLPLEGWNHVVKLLCGSLTRLLDSVRAIQAA
     890       900       910       920       930       940         

              970       980       990      1000      1010      1020
pF1KB2 GPWVQGPEQDLTQEALFVYTQVFCHALHIMAMLHPEVCEPLYVLALETLTCYETLSKTNP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPWVQGPEQDLTQEALFVYTQVFCHALHIMAMLHPEVCEPLYVLALETLTCYETLSKTNP
     950       960       970       980       990      1000         

             1030      1040      1050        
pF1KB2 SVSSLLQRAHEQRFLKSIAEGIGPEERRQTLLQKMSSF
       ::::::::::::::::::::::::::::::::::::::
XP_011 SVSSLLQRAHEQRFLKSIAEGIGPEERRQTLLQKMSSF
    1010      1020      1030      1040       

>>XP_011522215 (OMIM: 606969) PREDICTED: gem-associated   (1047 aa)
 initn: 6967 init1: 6967 opt: 6967  Z-score: 8381.3  bits: 1562.5 E(85289):    0
Smith-Waterman score: 6967; 99.7% identity (99.9% similar) in 1047 aa overlap (12-1058:1-1047)

               10        20        30        40        50        60
pF1KB2 MDLGPLNICEEMTILHGGFLLAEQLFHPKALAELTKSDWERVGRPIVEALREISSAAAHS
                  :::::::::::::::::::::::::::::::::::::::::::::::::
XP_011            MTILHGGFLLAEQLFHPKALAELTKSDWERVGRPIVEALREISSAAAHS
                          10        20        30        40         

               70        80        90       100       110       120
pF1KB2 QPFAWKKKALIIIWAKVLQPHPVTPSDTETRWQEDLFFSVGNMIPTINHTILFELLKSLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QPFAWKKKALIIIWAKVLQPHPVTPSDTETRWQEDLFFSVGNMIPTINHTILFELLKSLE
      50        60        70        80        90       100         

              130       140       150       160       170       180
pF1KB2 ASGLFIQLLMALPTTICHAELERFLEHVTVDTSAEDVAFFLDVWWEVMKHKGHPQDPLLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASGLFIQLLMALPTTICHAELERFLEHVTVDTSAEDVAFFLDVWWEVMKHKGHPQDPLLS
     110       120       130       140       150       160         

              190       200       210       220       230       240
pF1KB2 QFSAMAHKYLPALDEFPHPPKRLRSDPDACPTMPLLAMLLRGLTQIQSRILGPGRKCCAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QFSAMAHKYLPALDEFPHPPKRLRSDPDACPTMPLLAMLLRGLTQIQSRILGPGRKCCAL
     170       180       190       200       210       220         

              250       260       270       280       290       300
pF1KB2 ANLADMLTVFALTEDDPQEVSATVYLDKLATVISVWNSDTQNPYHQQALAEKVKEAERDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ANLADMLTVFALTEDDPQEVSATVYLDKLATVISVWNSDTQNPYHQQALAEKVKEAERDV
     230       240       250       260       270       280         

              310       320       330       340       350       360
pF1KB2 SLTSLAKLPSETIFVGCEFLHHLLREWGEELQAVLRSSQGTSYDSYRLCDSLTSFSQNAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLTSLAKLPSETIFVGCEFLHHLLREWGEELQAVLRSSQGTSYDSYRLCDSLTSFSQNAT
     290       300       310       320       330       340         

              370       380       390       400       410       420
pF1KB2 LYLNRTSLSKEDRQVVSELAECVRDFLRKTSTVLKNRALEDITASIAMAVIQQKMDRHME
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LYLNRTSLSKEDRQVVSELAECVRDFLRKTSTVLKNRALEDITASIAMAVIQQKMDRHME
     350       360       370       380       390       400         

              430       440       450       460       470       480
pF1KB2 VCYIFASEKKWAFSDEWVACLGSNRALFREPDLVLRLLETVIDVSTADRAIPESQIRQVI
       :::::::::::::::::::::::::::::.::::::::::::::::::::::::::::::
XP_011 VCYIFASEKKWAFSDEWVACLGSNRALFRQPDLVLRLLETVIDVSTADRAIPESQIRQVI
     410       420       430       440       450       460         

              490       500       510       520       530       540
pF1KB2 HLILECYADLSLPGKNKVLAGILRSWGRKGLSEKLLAYVEGFQEDLNTTFNQLTQSASEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HLILECYADLSLPGKNKVLAGILRSWGRKGLSEKLLAYVEGFQEDLNTTFNQLTQSASEQ
     470       480       490       500       510       520         

              550       560       570       580       590       600
pF1KB2 GLAKAVASVARLVIVHPEVTVKKMCSLAVVNLGTHKFLAQILTAFPALRFVEVQGPNSSA
       :::::::::::::::::::::::::::::::::::::::::::::::::::: :::::::
XP_011 GLAKAVASVARLVIVHPEVTVKKMCSLAVVNLGTHKFLAQILTAFPALRFVEEQGPNSSA
     530       540       550       560       570       580         

              610       620       630       640       650       660
pF1KB2 TFMVSCLKETVWMKFSTPKEEKQFLELLNCLMSPVKPQGIPVAALLEPDEVLKEFVLPFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TFMVSCLKETVWMKFSTPKEEKQFLELLNCLMSPVKPQGIPVAALLEPDEVLKEFVLPFL
     590       600       610       620       630       640         

              670       680       690       700       710       720
pF1KB2 RLDVEEVDLSLRIFIQTLEANACREEYWLQTCSPFPLLFSLCQLLDRFSKYWQLPKEKRC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLDVEEVDLSLRIFIQTLEANACREEYWLQTCSPFPLLFSLCQLLDRFSKYWQLPKEKRC
     650       660       670       680       690       700         

              730       740       750       760       770       780
pF1KB2 LSLDRKDLAIHILELLCEIVSANAETFSPDVWIKSLSWLHRKLEQLDWTVGLRLKSFFEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSLDRKDLAIHILELLCEIVSANAETFSPDVWIKSLSWLHRKLEQLDWTVGLRLKSFFEG
     710       720       730       740       750       760         

              790       800       810       820       830       840
pF1KB2 HFKCEVPATLFEICKLSEDEWTSQAHPGYGAGTGLLAWMECCCVSSGISERMLSLLVVDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HFKCEVPATLFEICKLSEDEWTSQAHPGYGAGTGLLAWMECCCVSSGISERMLSLLVVDV
     770       780       790       800       810       820         

              850       860       870       880       890       900
pF1KB2 GNPEEVRLFSKGFLVALVQVMPWCSPQEWQRLHQLTRRLLEKQLLHVPYSLEYIQFVPLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GNPEEVRLFSKGFLVALVQVMPWCSPQEWQRLHQLTRRLLEKQLLHVPYSLEYIQFVPLL
     830       840       850       860       870       880         

              910       920       930       940       950       960
pF1KB2 NLKPFAQELQLSVLFLRTFQFLCSHSCRNWLPLEGWNHVVKLLCGSLTRLLDSVRAIQAA
       ::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::
XP_011 NLKPFAQELQLSVLFLRTFQFLCSHSCRDWLPLEGWNHVVKLLCGSLTRLLDSVRAIQAA
     890       900       910       920       930       940         

              970       980       990      1000      1010      1020
pF1KB2 GPWVQGPEQDLTQEALFVYTQVFCHALHIMAMLHPEVCEPLYVLALETLTCYETLSKTNP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPWVQGPEQDLTQEALFVYTQVFCHALHIMAMLHPEVCEPLYVLALETLTCYETLSKTNP
     950       960       970       980       990      1000         

             1030      1040      1050        
pF1KB2 SVSSLLQRAHEQRFLKSIAEGIGPEERRQTLLQKMSSF
       ::::::::::::::::::::::::::::::::::::::
XP_011 SVSSLLQRAHEQRFLKSIAEGIGPEERRQTLLQKMSSF
    1010      1020      1030      1040       




1058 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 12:00:59 2016 done: Thu Nov  3 12:01:01 2016
 Total Scan time: 14.600 Total Display time:  0.350

Function used was FASTA [36.3.4 Apr, 2011]
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