Result of FASTA (omim) for pF1KB1326
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB1326, 942 aa
  1>>>pF1KB1326 942 - 942 aa - 942 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 8.4174+/-0.000404; mu= 8.2200+/- 0.025
 mean_var=219.2983+/-45.225, 0's: 0 Z-trim(120.1): 170  B-trim: 63 in 1/50
 Lambda= 0.086608
 statistics sampled from 34629 (34828) to 34629 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.729), E-opt: 0.2 (0.408), width:  16
 Scan time: 15.290

The best scores are:                                      opt bits E(85289)
NP_001338 (OMIM: 601207) diacylglycerol kinase the ( 942) 6516 827.8       0
XP_011511713 (OMIM: 601207) PREDICTED: diacylglyce ( 942) 6168 784.3       0
XP_011511714 (OMIM: 601207) PREDICTED: diacylglyce ( 630) 4404 563.8 9.8e-160
XP_016863303 (OMIM: 601207) PREDICTED: diacylglyce ( 597) 4059 520.6  9e-147
XP_011511716 (OMIM: 601207) PREDICTED: diacylglyce ( 583) 4036 517.8 6.4e-146
XP_011511717 (OMIM: 601207) PREDICTED: diacylglyce ( 486) 3426 441.5  5e-123
XP_016863304 (OMIM: 601207) PREDICTED: diacylglyce ( 481) 3395 437.6 7.2e-122
NP_003638 (OMIM: 601440,615008) diacylglycerol kin ( 567)  871 122.3   7e-27
XP_011523696 (OMIM: 601440,615008) PREDICTED: diac ( 585)  871 122.3 7.2e-27
XP_011518725 (OMIM: 601441) PREDICTED: diacylglyce ( 809)  832 117.6 2.7e-25
NP_001186197 (OMIM: 601441) diacylglycerol kinase  ( 906)  832 117.6 2.9e-25
XP_011518724 (OMIM: 601441) PREDICTED: diacylglyce ( 911)  832 117.6 2.9e-25
NP_001186196 (OMIM: 601441) diacylglycerol kinase  ( 928)  832 117.6 2.9e-25
NP_003637 (OMIM: 601441) diacylglycerol kinase zet ( 929)  832 117.6   3e-25
NP_963291 (OMIM: 601441) diacylglycerol kinase zet ( 933)  832 117.6   3e-25
XP_006718418 (OMIM: 601441) PREDICTED: diacylglyce ( 933)  832 117.6   3e-25
XP_005253239 (OMIM: 601441) PREDICTED: diacylglyce ( 934)  832 117.6   3e-25
NP_001186195 (OMIM: 601441) diacylglycerol kinase  ( 934)  832 117.6   3e-25
NP_963290 (OMIM: 601441) diacylglycerol kinase zet ( 945)  832 117.6   3e-25
XP_005253238 (OMIM: 601441) PREDICTED: diacylglyce ( 946)  832 117.6   3e-25
NP_001099010 (OMIM: 601441) diacylglycerol kinase  (1117)  832 117.7 3.4e-25
XP_006718417 (OMIM: 601441) PREDICTED: diacylglyce (1118)  832 117.7 3.4e-25
XP_016873946 (OMIM: 601441) PREDICTED: diacylglyce (1153)  832 117.7 3.5e-25
XP_016873945 (OMIM: 601441) PREDICTED: diacylglyce (1175)  832 117.7 3.5e-25
XP_016873944 (OMIM: 601441) PREDICTED: diacylglyce (1176)  832 117.7 3.5e-25
XP_011523697 (OMIM: 601440,615008) PREDICTED: diac ( 543)  788 111.9   9e-24
XP_011514986 (OMIM: 604072) PREDICTED: diacylglyce ( 724)  781 111.1   2e-23
NP_001308639 (OMIM: 604072) diacylglycerol kinase  ( 734)  781 111.1 2.1e-23
XP_016868277 (OMIM: 604072) PREDICTED: diacylglyce ( 757)  781 111.2 2.1e-23
NP_001308638 (OMIM: 604072) diacylglycerol kinase  ( 757)  781 111.2 2.1e-23
XP_016868275 (OMIM: 604072) PREDICTED: diacylglyce ( 778)  781 111.2 2.1e-23
XP_016868276 (OMIM: 604072) PREDICTED: diacylglyce ( 778)  781 111.2 2.1e-23
XP_016868274 (OMIM: 604072) PREDICTED: diacylglyce ( 879)  781 111.2 2.3e-23
XP_011514984 (OMIM: 604072) PREDICTED: diacylglyce ( 946)  781 111.2 2.5e-23
XP_016868273 (OMIM: 604072) PREDICTED: diacylglyce ( 963)  781 111.2 2.5e-23
XP_016868272 (OMIM: 604072) PREDICTED: diacylglyce ( 985)  781 111.3 2.6e-23
XP_016868270 (OMIM: 604072) PREDICTED: diacylglyce (1021)  781 111.3 2.6e-23
NP_001308637 (OMIM: 604072) diacylglycerol kinase  (1057)  781 111.3 2.7e-23
NP_004708 (OMIM: 604072) diacylglycerol kinase iot (1065)  781 111.3 2.7e-23
XP_016868269 (OMIM: 604072) PREDICTED: diacylglyce (1078)  781 111.3 2.7e-23
XP_016880732 (OMIM: 601440,615008) PREDICTED: diac ( 691)  629 92.1   1e-17
XP_016867279 (OMIM: 604070) PREDICTED: diacylglyce ( 725)  584 86.5 5.2e-16
NP_663733 (OMIM: 604070) diacylglycerol kinase bet ( 773)  584 86.5 5.5e-16
XP_011513460 (OMIM: 604070) PREDICTED: diacylglyce ( 785)  584 86.6 5.6e-16
XP_005249688 (OMIM: 604070) PREDICTED: diacylglyce ( 785)  584 86.6 5.6e-16
XP_016867278 (OMIM: 604070) PREDICTED: diacylglyce ( 792)  584 86.6 5.6e-16
XP_016867277 (OMIM: 604070) PREDICTED: diacylglyce ( 792)  584 86.6 5.6e-16
XP_011513459 (OMIM: 604070) PREDICTED: diacylglyce ( 792)  584 86.6 5.6e-16
XP_011513458 (OMIM: 604070) PREDICTED: diacylglyce ( 796)  584 86.6 5.6e-16
XP_016867275 (OMIM: 604070) PREDICTED: diacylglyce ( 796)  584 86.6 5.6e-16


>>NP_001338 (OMIM: 601207) diacylglycerol kinase theta [  (942 aa)
 initn: 6516 init1: 6516 opt: 6516  Z-score: 4412.6  bits: 827.8 E(85289):    0
Smith-Waterman score: 6516; 99.9% identity (100.0% similar) in 942 aa overlap (1-942:1-942)

               10        20        30        40        50        60
pF1KB1 MAAAAEPGARAWLGGGSPRPGSPACSPVLGSGGRARPGPGPGPGPERAGVRAPGPAAAPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAAAEPGARAWLGGGSPRPGSPACSPVLGSGGRARPGPGPGPGPERAGVRAPGPAAAPG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB1 HSFRKVTLTKPTFCHLCSDFIWGLAGFLCDVCNFMSHEKCLKHVRIPCTSVAPSLVRVPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HSFRKVTLTKPTFCHLCSDFIWGLAGFLCDVCNFMSHEKCLKHVRIPCTSVAPSLVRVPV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB1 AHCFGPRGLHKRKFCAVCRKVLEAPALHCEVCELHLHPDCVPFACSDCRQCHQDGHQDHD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AHCFGPRGLHKRKFCAVCRKVLEAPALHCEVCELHLHPDCVPFACSDCRQCHQDGHQDHD
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB1 THHHHWREGNLPSGARCEVCRKTCGSSDVLAGVRCEWCGVQAHSLCSAALAPECGFGRLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 THHHHWREGNLPSGARCEVCRKTCGSSDVLAGVRCEWCGVQAHSLCSAALAPECGFGRLR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB1 SLVLPPACVRLLPGGFSKTQSFRIVEAAEPGEGGDGADGSAAVGPGRETQATPESGKQTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLVLPPACVRLLPGGFSKTQSFRIVEAAEPGEGGDGADGSAAVGPGRETQATPESGKQTL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB1 KIFDGDDAVRRSQFRLVTVSRLAGAEEVLEAALRAHHIPEDPGHLELCRLPPSSQACDAW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KIFDGDDAVRRSQFRLVTVSRLAGAEEVLEAALRAHHIPEDPGHLELCRLPPSSQACDAW
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB1 AGGKAGSAVISEEGRSPGSGEATPEAWVIRALPRAQEVLKIYPGWLKVGVAYVSVRVTPK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGGKAGSAVISEEGRSPGSGEATPEAWVIRALPRAQEVLKIYPGWLKVGVAYVSVRVTPK
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB1 STARSVVLEVLPLLGRQAESPESFQLVEVAMGCRHVQRTMLMDEQPLLDRLQDIRQMSVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STARSVVLEVLPLLGRQAESPESFQLVEVAMGCRHVQRTMLMDEQPLLDRLQDIRQMSVR
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB1 QVSQTRFYVAESRDVAPHVSLFVGGLPPGLSPEEYSSLLHEAGATKATVVSVSHIYSSQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QVSQTRFYVAESRDVAPHVSLFVGGLPPGLSPEEYSSLLHEAGATKATVVSVSHIYSSQG
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB1 AVVLDVACFAEAERLYMLLKDMAVRGRLLTALVLPDLLHAKLPPDSCPLLVFVNPKSGGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVVLDVACFAEAERLYMLLKDMAVRGRLLTALVLPDLLHAKLPPDSCPLLVFVNPKSGGL
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB1 KGRDLLCSFRKLLNPHQVFDLTNGGPLPGLHLFSQVPCFRVLVCGGDGTVGWVLGALEET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGRDLLCSFRKLLNPHQVFDLTNGGPLPGLHLFSQVPCFRVLVCGGDGTVGWVLGALEET
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB1 RYRLACPEPSVAILPLGTGNDLGRVLRWGAGYSGEDPFSVLLSVDEADAVLMDRWTILLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RYRLACPEPSVAILPLGTGNDLGRVLRWGAGYSGEDPFSVLLSVDEADAVLMDRWTILLD
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB1 AHEAGSAENDTADAEPPKIVQMSNYCGIGIDAELSLDFHQAREEEPGKFTSRLHNKGVYV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AHEAGSAENDTADAEPPKIVQMSNYCGIGIDAELSLDFHQAREEEPGKFTSRLHNKGVYV
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB1 RVGLQKISHSRSLHKQIRLQVERQEVELPSIEGLIFINIPSWGSGADLWGSDSDTRFEKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RVGLQKISHSRSLHKQIRLQVERQEVELPSIEGLIFINIPSWGSGADLWGSDSDTRFEKP
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB1 RMDDGLLEVVGVTGVVYMGQVQGGLRSGIRIAQGSYFRVTLLKATPVQVDGEPWVQAPGH
       ::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::
NP_001 RMDDGLLEVVGVTGVVHMGQVQGGLRSGIRIAQGSYFRVTLLKATPVQVDGEPWVQAPGH
              850       860       870       880       890       900

              910       920       930       940  
pF1KB1 MIISAAGPKVHMLRKAKQKPRRAGTTRDARADAAPAPESDPR
       ::::::::::::::::::::::::::::::::::::::::::
NP_001 MIISAAGPKVHMLRKAKQKPRRAGTTRDARADAAPAPESDPR
              910       920       930       940  

>>XP_011511713 (OMIM: 601207) PREDICTED: diacylglycerol   (942 aa)
 initn: 6133 init1: 6133 opt: 6168  Z-score: 4177.6  bits: 784.3 E(85289):    0
Smith-Waterman score: 6168; 95.3% identity (96.6% similar) in 945 aa overlap (1-942:1-942)

               10        20        30        40        50        60
pF1KB1 MAAAAEPGARAWLGGGSPRPGSPACSPVLGSGGRARPGPGPGPGPERAGVRAPGPAAAPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAAAAEPGARAWLGGGSPRPGSPACSPVLGSGGRARPGPGPGPGPERAGVRAPGPAAAPG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB1 HSFRKVTLTKPTFCHLCSDFIWGLAGFLCDVCNFMSHEKCLKHVRIPCTSVAPSLVRVPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HSFRKVTLTKPTFCHLCSDFIWGLAGFLCDVCNFMSHEKCLKHVRIPCTSVAPSLVRVPV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB1 AHCFGPRGLHKRKFCAVCRKVLEAPALHCEVCELHLHPDCVPFACSDCRQCHQDGHQDHD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AHCFGPRGLHKRKFCAVCRKVLEAPALHCEVCELHLHPDCVPFACSDCRQCHQDGHQDHD
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB1 THHHHWREGNLPSGARCEVCRKTCGSSDVLAGVRCEWCGVQAHSLCSAALAPECGFGRLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 THHHHWREGNLPSGARCEVCRKTCGSSDVLAGVRCEWCGVQAHSLCSAALAPECGFGRLR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB1 SLVLPPACVRLLPGGFSKTQSFRIVEAAEPGEGGDGADGSAAVGPGRETQATPESGKQTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLVLPPACVRLLPGGFSKTQSFRIVEAAEPGEGGDGADGSAAVGPGRETQATPESGKQTL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB1 KIFDGDDAVRRSQFRLVTVSRLAGAEEVLEAALRAHHIPEDPGHLELCRLPPSSQACDAW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KIFDGDDAVRRSQFRLVTVSRLAGAEEVLEAALRAHHIPEDPGHLELCRLPPSSQACDAW
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB1 AGGKAGSAVISEEGRSPGSGEATPEAWVIRALPRAQEVLKIYPGWLKVGVAYVSVRVTPK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGGKAGSAVISEEGRSPGSGEATPEAWVIRALPRAQEVLKIYPGWLKVGVAYVSVRVTPK
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB1 STARSVVLEVLPLLGRQAESPESFQLVEVAMGCRHVQRTMLMDEQPLLDRLQDIRQMSVR
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::: ...
XP_011 STARSVVLEVLPLLGRQAESPESFQLVEVAMGCRHVQRTMLMDEQPLLDRLQDIRQGGLE
              430       440       450       460       470       480

              490       500          510       520       530       
pF1KB1 QVSQTRFYVAESRDVAPHVSLFVGGLP--P-GLSPEEYSSLLHEAGATKATVVSVSHIYS
          . :   . .:   :. . . : .:  :  : :    . :    :  :::::::::::
XP_011 LQISPRSSRGTDRGC-PQQGSLCGPFPRFPVDLIPGSVPDALFCCFA--ATVVSVSHIYS
              490        500       510       520         530       

       540       550       560       570       580       590       
pF1KB1 SQGAVVLDVACFAEAERLYMLLKDMAVRGRLLTALVLPDLLHAKLPPDSCPLLVFVNPKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQGAVVLDVACFAEAERLYMLLKDMAVRGRLLTALVLPDLLHAKLPPDSCPLLVFVNPKS
       540       550       560       570       580       590       

       600       610       620       630       640       650       
pF1KB1 GGLKGRDLLCSFRKLLNPHQVFDLTNGGPLPGLHLFSQVPCFRVLVCGGDGTVGWVLGAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGLKGRDLLCSFRKLLNPHQVFDLTNGGPLPGLHLFSQVPCFRVLVCGGDGTVGWVLGAL
       600       610       620       630       640       650       

       660       670       680       690       700       710       
pF1KB1 EETRYRLACPEPSVAILPLGTGNDLGRVLRWGAGYSGEDPFSVLLSVDEADAVLMDRWTI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EETRYRLACPEPSVAILPLGTGNDLGRVLRWGAGYSGEDPFSVLLSVDEADAVLMDRWTI
       660       670       680       690       700       710       

       720       730       740       750       760       770       
pF1KB1 LLDAHEAGSAENDTADAEPPKIVQMSNYCGIGIDAELSLDFHQAREEEPGKFTSRLHNKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLDAHEAGSAENDTADAEPPKIVQMSNYCGIGIDAELSLDFHQAREEEPGKFTSRLHNKG
       720       730       740       750       760       770       

       780       790       800       810       820       830       
pF1KB1 VYVRVGLQKISHSRSLHKQIRLQVERQEVELPSIEGLIFINIPSWGSGADLWGSDSDTRF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VYVRVGLQKISHSRSLHKQIRLQVERQEVELPSIEGLIFINIPSWGSGADLWGSDSDTRF
       780       790       800       810       820       830       

       840       850       860       870       880       890       
pF1KB1 EKPRMDDGLLEVVGVTGVVYMGQVQGGLRSGIRIAQGSYFRVTLLKATPVQVDGEPWVQA
       :::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::
XP_011 EKPRMDDGLLEVVGVTGVVHMGQVQGGLRSGIRIAQGSYFRVTLLKATPVQVDGEPWVQA
       840       850       860       870       880       890       

       900       910       920       930       940  
pF1KB1 PGHMIISAAGPKVHMLRKAKQKPRRAGTTRDARADAAPAPESDPR
       :::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGHMIISAAGPKVHMLRKAKQKPRRAGTTRDARADAAPAPESDPR
       900       910       920       930       940  

>>XP_011511714 (OMIM: 601207) PREDICTED: diacylglycerol   (630 aa)
 initn: 4404 init1: 4404 opt: 4404  Z-score: 2988.7  bits: 563.8 E(85289): 9.8e-160
Smith-Waterman score: 4404; 100.0% identity (100.0% similar) in 629 aa overlap (1-629:1-629)

               10        20        30        40        50        60
pF1KB1 MAAAAEPGARAWLGGGSPRPGSPACSPVLGSGGRARPGPGPGPGPERAGVRAPGPAAAPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAAAAEPGARAWLGGGSPRPGSPACSPVLGSGGRARPGPGPGPGPERAGVRAPGPAAAPG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB1 HSFRKVTLTKPTFCHLCSDFIWGLAGFLCDVCNFMSHEKCLKHVRIPCTSVAPSLVRVPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HSFRKVTLTKPTFCHLCSDFIWGLAGFLCDVCNFMSHEKCLKHVRIPCTSVAPSLVRVPV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB1 AHCFGPRGLHKRKFCAVCRKVLEAPALHCEVCELHLHPDCVPFACSDCRQCHQDGHQDHD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AHCFGPRGLHKRKFCAVCRKVLEAPALHCEVCELHLHPDCVPFACSDCRQCHQDGHQDHD
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB1 THHHHWREGNLPSGARCEVCRKTCGSSDVLAGVRCEWCGVQAHSLCSAALAPECGFGRLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 THHHHWREGNLPSGARCEVCRKTCGSSDVLAGVRCEWCGVQAHSLCSAALAPECGFGRLR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB1 SLVLPPACVRLLPGGFSKTQSFRIVEAAEPGEGGDGADGSAAVGPGRETQATPESGKQTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLVLPPACVRLLPGGFSKTQSFRIVEAAEPGEGGDGADGSAAVGPGRETQATPESGKQTL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB1 KIFDGDDAVRRSQFRLVTVSRLAGAEEVLEAALRAHHIPEDPGHLELCRLPPSSQACDAW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KIFDGDDAVRRSQFRLVTVSRLAGAEEVLEAALRAHHIPEDPGHLELCRLPPSSQACDAW
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB1 AGGKAGSAVISEEGRSPGSGEATPEAWVIRALPRAQEVLKIYPGWLKVGVAYVSVRVTPK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGGKAGSAVISEEGRSPGSGEATPEAWVIRALPRAQEVLKIYPGWLKVGVAYVSVRVTPK
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB1 STARSVVLEVLPLLGRQAESPESFQLVEVAMGCRHVQRTMLMDEQPLLDRLQDIRQMSVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STARSVVLEVLPLLGRQAESPESFQLVEVAMGCRHVQRTMLMDEQPLLDRLQDIRQMSVR
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB1 QVSQTRFYVAESRDVAPHVSLFVGGLPPGLSPEEYSSLLHEAGATKATVVSVSHIYSSQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QVSQTRFYVAESRDVAPHVSLFVGGLPPGLSPEEYSSLLHEAGATKATVVSVSHIYSSQG
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB1 AVVLDVACFAEAERLYMLLKDMAVRGRLLTALVLPDLLHAKLPPDSCPLLVFVNPKSGGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVVLDVACFAEAERLYMLLKDMAVRGRLLTALVLPDLLHAKLPPDSCPLLVFVNPKSGGL
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB1 KGRDLLCSFRKLLNPHQVFDLTNGGPLPGLHLFSQVPCFRVLVCGGDGTVGWVLGALEET
       :::::::::::::::::::::::::::::                               
XP_011 KGRDLLCSFRKLLNPHQVFDLTNGGPLPGE                              
              610       620       630                              

>>XP_016863303 (OMIM: 601207) PREDICTED: diacylglycerol   (597 aa)
 initn: 4059 init1: 4059 opt: 4059  Z-score: 2756.1  bits: 520.6 E(85289): 9e-147
Smith-Waterman score: 4059; 99.0% identity (99.0% similar) in 588 aa overlap (1-588:1-588)

               10        20        30        40        50        60
pF1KB1 MAAAAEPGARAWLGGGSPRPGSPACSPVLGSGGRARPGPGPGPGPERAGVRAPGPAAAPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAAAAEPGARAWLGGGSPRPGSPACSPVLGSGGRARPGPGPGPGPERAGVRAPGPAAAPG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB1 HSFRKVTLTKPTFCHLCSDFIWGLAGFLCDVCNFMSHEKCLKHVRIPCTSVAPSLVRVPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HSFRKVTLTKPTFCHLCSDFIWGLAGFLCDVCNFMSHEKCLKHVRIPCTSVAPSLVRVPV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB1 AHCFGPRGLHKRKFCAVCRKVLEAPALHCEVCELHLHPDCVPFACSDCRQCHQDGHQDHD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AHCFGPRGLHKRKFCAVCRKVLEAPALHCEVCELHLHPDCVPFACSDCRQCHQDGHQDHD
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB1 THHHHWREGNLPSGARCEVCRKTCGSSDVLAGVRCEWCGVQAHSLCSAALAPECGFGRLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 THHHHWREGNLPSGARCEVCRKTCGSSDVLAGVRCEWCGVQAHSLCSAALAPECGFGRLR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB1 SLVLPPACVRLLPGGFSKTQSFRIVEAAEPGEGGDGADGSAAVGPGRETQATPESGKQTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLVLPPACVRLLPGGFSKTQSFRIVEAAEPGEGGDGADGSAAVGPGRETQATPESGKQTL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB1 KIFDGDDAVRRSQFRLVTVSRLAGAEEVLEAALRAHHIPEDPGHLELCRLPPSSQACDAW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KIFDGDDAVRRSQFRLVTVSRLAGAEEVLEAALRAHHIPEDPGHLELCRLPPSSQACDAW
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB1 AGGKAGSAVISEEGRSPGSGEATPEAWVIRALPRAQEVLKIYPGWLKVGVAYVSVRVTPK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGGKAGSAVISEEGRSPGSGEATPEAWVIRALPRAQEVLKIYPGWLKVGVAYVSVRVTPK
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB1 STARSVVLEVLPLLGRQAESPESFQLVEVAMGCRHVQRTMLMDEQPLLDRLQDIRQMSVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STARSVVLEVLPLLGRQAESPESFQLVEVAMGCRHVQRTMLMDEQPLLDRLQDIRQMSVR
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB1 QVSQTRFYVAESRDVAPHVSLFVGGLPPGLSPEEYSSLLHEAGATKATVVSVSHIYSSQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QVSQTRFYVAESRDVAPHVSLFVGGLPPGLSPEEYSSLLHEAGATKATVVSVSHIYSSQG
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB1 AVVLDVACFAEAERLYMLLKDMAVRGRLLTALVLPDLLHAKLPPDSCPLLVFVNPKSGGL
       ::::::::::::::::::::::::::::::::::::::   :   :::            
XP_016 AVVLDVACFAEAERLYMLLKDMAVRGRLLTALVLPDLLLPALGTRSCPQTAVPSLCS   
              550       560       570       580       590          

              610       620       630       640       650       660
pF1KB1 KGRDLLCSFRKLLNPHQVFDLTNGGPLPGLHLFSQVPCFRVLVCGGDGTVGWVLGALEET

>>XP_011511716 (OMIM: 601207) PREDICTED: diacylglycerol   (583 aa)
 initn: 4036 init1: 4036 opt: 4036  Z-score: 2740.7  bits: 517.8 E(85289): 6.4e-146
Smith-Waterman score: 4036; 100.0% identity (100.0% similar) in 578 aa overlap (1-578:1-578)

               10        20        30        40        50        60
pF1KB1 MAAAAEPGARAWLGGGSPRPGSPACSPVLGSGGRARPGPGPGPGPERAGVRAPGPAAAPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAAAAEPGARAWLGGGSPRPGSPACSPVLGSGGRARPGPGPGPGPERAGVRAPGPAAAPG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB1 HSFRKVTLTKPTFCHLCSDFIWGLAGFLCDVCNFMSHEKCLKHVRIPCTSVAPSLVRVPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HSFRKVTLTKPTFCHLCSDFIWGLAGFLCDVCNFMSHEKCLKHVRIPCTSVAPSLVRVPV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB1 AHCFGPRGLHKRKFCAVCRKVLEAPALHCEVCELHLHPDCVPFACSDCRQCHQDGHQDHD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AHCFGPRGLHKRKFCAVCRKVLEAPALHCEVCELHLHPDCVPFACSDCRQCHQDGHQDHD
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB1 THHHHWREGNLPSGARCEVCRKTCGSSDVLAGVRCEWCGVQAHSLCSAALAPECGFGRLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 THHHHWREGNLPSGARCEVCRKTCGSSDVLAGVRCEWCGVQAHSLCSAALAPECGFGRLR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB1 SLVLPPACVRLLPGGFSKTQSFRIVEAAEPGEGGDGADGSAAVGPGRETQATPESGKQTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLVLPPACVRLLPGGFSKTQSFRIVEAAEPGEGGDGADGSAAVGPGRETQATPESGKQTL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB1 KIFDGDDAVRRSQFRLVTVSRLAGAEEVLEAALRAHHIPEDPGHLELCRLPPSSQACDAW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KIFDGDDAVRRSQFRLVTVSRLAGAEEVLEAALRAHHIPEDPGHLELCRLPPSSQACDAW
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB1 AGGKAGSAVISEEGRSPGSGEATPEAWVIRALPRAQEVLKIYPGWLKVGVAYVSVRVTPK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGGKAGSAVISEEGRSPGSGEATPEAWVIRALPRAQEVLKIYPGWLKVGVAYVSVRVTPK
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB1 STARSVVLEVLPLLGRQAESPESFQLVEVAMGCRHVQRTMLMDEQPLLDRLQDIRQMSVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STARSVVLEVLPLLGRQAESPESFQLVEVAMGCRHVQRTMLMDEQPLLDRLQDIRQMSVR
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB1 QVSQTRFYVAESRDVAPHVSLFVGGLPPGLSPEEYSSLLHEAGATKATVVSVSHIYSSQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QVSQTRFYVAESRDVAPHVSLFVGGLPPGLSPEEYSSLLHEAGATKATVVSVSHIYSSQG
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB1 AVVLDVACFAEAERLYMLLKDMAVRGRLLTALVLPDLLHAKLPPDSCPLLVFVNPKSGGL
       ::::::::::::::::::::::::::::::::::::::                      
XP_011 AVVLDVACFAEAERLYMLLKDMAVRGRLLTALVLPDLLLPALG                 
              550       560       570       580                    

              610       620       630       640       650       660
pF1KB1 KGRDLLCSFRKLLNPHQVFDLTNGGPLPGLHLFSQVPCFRVLVCGGDGTVGWVLGALEET

>>XP_011511717 (OMIM: 601207) PREDICTED: diacylglycerol   (486 aa)
 initn: 3426 init1: 3426 opt: 3426  Z-score: 2329.8  bits: 441.5 E(85289): 5e-123
Smith-Waterman score: 3426; 100.0% identity (100.0% similar) in 481 aa overlap (1-481:1-481)

               10        20        30        40        50        60
pF1KB1 MAAAAEPGARAWLGGGSPRPGSPACSPVLGSGGRARPGPGPGPGPERAGVRAPGPAAAPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAAAAEPGARAWLGGGSPRPGSPACSPVLGSGGRARPGPGPGPGPERAGVRAPGPAAAPG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB1 HSFRKVTLTKPTFCHLCSDFIWGLAGFLCDVCNFMSHEKCLKHVRIPCTSVAPSLVRVPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HSFRKVTLTKPTFCHLCSDFIWGLAGFLCDVCNFMSHEKCLKHVRIPCTSVAPSLVRVPV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB1 AHCFGPRGLHKRKFCAVCRKVLEAPALHCEVCELHLHPDCVPFACSDCRQCHQDGHQDHD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AHCFGPRGLHKRKFCAVCRKVLEAPALHCEVCELHLHPDCVPFACSDCRQCHQDGHQDHD
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB1 THHHHWREGNLPSGARCEVCRKTCGSSDVLAGVRCEWCGVQAHSLCSAALAPECGFGRLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 THHHHWREGNLPSGARCEVCRKTCGSSDVLAGVRCEWCGVQAHSLCSAALAPECGFGRLR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB1 SLVLPPACVRLLPGGFSKTQSFRIVEAAEPGEGGDGADGSAAVGPGRETQATPESGKQTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLVLPPACVRLLPGGFSKTQSFRIVEAAEPGEGGDGADGSAAVGPGRETQATPESGKQTL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB1 KIFDGDDAVRRSQFRLVTVSRLAGAEEVLEAALRAHHIPEDPGHLELCRLPPSSQACDAW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KIFDGDDAVRRSQFRLVTVSRLAGAEEVLEAALRAHHIPEDPGHLELCRLPPSSQACDAW
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB1 AGGKAGSAVISEEGRSPGSGEATPEAWVIRALPRAQEVLKIYPGWLKVGVAYVSVRVTPK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGGKAGSAVISEEGRSPGSGEATPEAWVIRALPRAQEVLKIYPGWLKVGVAYVSVRVTPK
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB1 STARSVVLEVLPLLGRQAESPESFQLVEVAMGCRHVQRTMLMDEQPLLDRLQDIRQMSVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STARSVVLEVLPLLGRQAESPESFQLVEVAMGCRHVQRTMLMDEQPLLDRLQDIRQMSVR
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB1 QVSQTRFYVAESRDVAPHVSLFVGGLPPGLSPEEYSSLLHEAGATKATVVSVSHIYSSQG
       :                                                           
XP_011 QPPWCP                                                      
                                                                   

>>XP_016863304 (OMIM: 601207) PREDICTED: diacylglycerol   (481 aa)
 initn: 3395 init1: 3395 opt: 3395  Z-score: 2308.9  bits: 437.6 E(85289): 7.2e-122
Smith-Waterman score: 3395; 100.0% identity (100.0% similar) in 476 aa overlap (1-476:1-476)

               10        20        30        40        50        60
pF1KB1 MAAAAEPGARAWLGGGSPRPGSPACSPVLGSGGRARPGPGPGPGPERAGVRAPGPAAAPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAAAAEPGARAWLGGGSPRPGSPACSPVLGSGGRARPGPGPGPGPERAGVRAPGPAAAPG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB1 HSFRKVTLTKPTFCHLCSDFIWGLAGFLCDVCNFMSHEKCLKHVRIPCTSVAPSLVRVPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HSFRKVTLTKPTFCHLCSDFIWGLAGFLCDVCNFMSHEKCLKHVRIPCTSVAPSLVRVPV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB1 AHCFGPRGLHKRKFCAVCRKVLEAPALHCEVCELHLHPDCVPFACSDCRQCHQDGHQDHD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AHCFGPRGLHKRKFCAVCRKVLEAPALHCEVCELHLHPDCVPFACSDCRQCHQDGHQDHD
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB1 THHHHWREGNLPSGARCEVCRKTCGSSDVLAGVRCEWCGVQAHSLCSAALAPECGFGRLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 THHHHWREGNLPSGARCEVCRKTCGSSDVLAGVRCEWCGVQAHSLCSAALAPECGFGRLR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB1 SLVLPPACVRLLPGGFSKTQSFRIVEAAEPGEGGDGADGSAAVGPGRETQATPESGKQTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLVLPPACVRLLPGGFSKTQSFRIVEAAEPGEGGDGADGSAAVGPGRETQATPESGKQTL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB1 KIFDGDDAVRRSQFRLVTVSRLAGAEEVLEAALRAHHIPEDPGHLELCRLPPSSQACDAW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KIFDGDDAVRRSQFRLVTVSRLAGAEEVLEAALRAHHIPEDPGHLELCRLPPSSQACDAW
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB1 AGGKAGSAVISEEGRSPGSGEATPEAWVIRALPRAQEVLKIYPGWLKVGVAYVSVRVTPK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGGKAGSAVISEEGRSPGSGEATPEAWVIRALPRAQEVLKIYPGWLKVGVAYVSVRVTPK
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB1 STARSVVLEVLPLLGRQAESPESFQLVEVAMGCRHVQRTMLMDEQPLLDRLQDIRQMSVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::    
XP_016 STARSVVLEVLPLLGRQAESPESFQLVEVAMGCRHVQRTMLMDEQPLLDRLQDIRQPPWC
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB1 QVSQTRFYVAESRDVAPHVSLFVGGLPPGLSPEEYSSLLHEAGATKATVVSVSHIYSSQG
                                                                   
XP_016 P                                                           
                                                                   

>>NP_003638 (OMIM: 601440,615008) diacylglycerol kinase   (567 aa)
 initn: 1003 init1: 248 opt: 871  Z-score: 603.6  bits: 122.3 E(85289): 7e-27
Smith-Waterman score: 871; 40.4% identity (67.3% similar) in 361 aa overlap (576-928:207-559)

         550       560       570       580       590       600     
pF1KB1 VACFAEAERLYMLLKDMAVRGRLLTALVLPDLLHAKLPPDSCPLLVFVNPKSGGLKGRDL
                                     ..: .::  .  ::....: .::   :. :
NP_003 CDFGEFKNLIIPPSYLTSINQMRKDKKTDYEVLASKLGKQWTPLIILANSRSGTNMGEGL
        180       190       200       210       220       230      

         610       620       630         640       650       660   
pF1KB1 LCSFRKLLNPHQVFDLTNGGPLPGLHLFSQVPCF--RVLVCGGDGTVGWVLGALEETRYR
       :  :: :::: ::::.:.  :. .:.: . .: .  ::::::::::::::: :... . .
NP_003 LGEFRILLNPVQVFDVTKTPPIKALQLCTLLPYYSARVLVCGGDGTVGWVLDAVDDMKIK
        240       250       260       270       280       290      

            670       680       690        700       710       720 
pF1KB1 LACPE-PSVAILPLGTGNDLGRVLRWGAGYSGEDPFS-VLLSVDEADAVLMDRWTILLDA
             :.::.:::::::::. .: ::.::.:: : . :: .: :::.. .::: . .  
NP_003 GQEKYIPQVAVLPLGTGNDLSNTLGWGTGYAGEIPVAQVLRNVMEADGIKLDRWKVQV--
        300       310       320       330       340       350      

             730       740       750       760       770       780 
pF1KB1 HEAGSAENDTADAEPPKIVQMSNYCGIGIDAELSLDFHQAREEEPGKFTSRLHNKGVYVR
            ...   . . ::   :.:: ..: :: ..:.::  ::. :. :.::. ::.::. 
NP_003 -----TNKGYYNLRKPKEFTMNNYFSVGPDALMALNFHAHREKAPSLFSSRILNKAVYLF
               360       370       380       390       400         

               790       800       810       820       830         
pF1KB1 VGLQK--ISHSRSLHKQIRLQVERQEVELPSIEGLIFINIPSWGSGADLWGSDSDTRFEK
        : .   ... ..:.:...:... ..: :::.::.: .::  ::.:  :: . .:  .  
NP_003 YGTKDCLVQECKDLNKKVELELDGERVALPSLEGIIVLNIGYWGGGCRLWEGMGDETYPL
     410       420       430       440       450       460         

     840       850       860       870       880         890       
pF1KB1 PRMDDGLLEVVGVTGVVYMGQVQGGLRSGIRIAQGSYFRVTLLKAT--PVQVDGEPWVQA
        : :::::::::: :  . .:.:  : . .::.:.   :. .:: .  :.:::::::.:.
NP_003 ARHDDGLLEVVGVYGSFHCAQIQVKLANPFRIGQAHTVRL-ILKCSMMPMQVDGEPWAQG
     470       480       490       500        510       520        

       900       910       920       930       940  
pF1KB1 PGHMIISAAGPKVHMLRKAKQKPRRAGTTRDARADAAPAPESDPR
       :  . :.     . .  ...:     ..: :              
NP_003 PCTVTITHKTHAMMLYFSGEQTDDDISSTSDQEDIKATE      
      530       540       550       560             

>>XP_011523696 (OMIM: 601440,615008) PREDICTED: diacylgl  (585 aa)
 initn: 1003 init1: 248 opt: 871  Z-score: 603.4  bits: 122.3 E(85289): 7.2e-27
Smith-Waterman score: 871; 40.4% identity (67.3% similar) in 361 aa overlap (576-928:225-577)

         550       560       570       580       590       600     
pF1KB1 VACFAEAERLYMLLKDMAVRGRLLTALVLPDLLHAKLPPDSCPLLVFVNPKSGGLKGRDL
                                     ..: .::  .  ::....: .::   :. :
XP_011 CDFGEFKNLIIPPSYLTSINQMRKDKKTDYEVLASKLGKQWTPLIILANSRSGTNMGEGL
          200       210       220       230       240       250    

         610       620       630         640       650       660   
pF1KB1 LCSFRKLLNPHQVFDLTNGGPLPGLHLFSQVPCF--RVLVCGGDGTVGWVLGALEETRYR
       :  :: :::: ::::.:.  :. .:.: . .: .  ::::::::::::::: :... . .
XP_011 LGEFRILLNPVQVFDVTKTPPIKALQLCTLLPYYSARVLVCGGDGTVGWVLDAVDDMKIK
          260       270       280       290       300       310    

            670       680       690        700       710       720 
pF1KB1 LACPE-PSVAILPLGTGNDLGRVLRWGAGYSGEDPFS-VLLSVDEADAVLMDRWTILLDA
             :.::.:::::::::. .: ::.::.:: : . :: .: :::.. .::: . .  
XP_011 GQEKYIPQVAVLPLGTGNDLSNTLGWGTGYAGEIPVAQVLRNVMEADGIKLDRWKVQV--
          320       330       340       350       360       370    

             730       740       750       760       770       780 
pF1KB1 HEAGSAENDTADAEPPKIVQMSNYCGIGIDAELSLDFHQAREEEPGKFTSRLHNKGVYVR
            ...   . . ::   :.:: ..: :: ..:.::  ::. :. :.::. ::.::. 
XP_011 -----TNKGYYNLRKPKEFTMNNYFSVGPDALMALNFHAHREKAPSLFSSRILNKAVYLF
                 380       390       400       410       420       

               790       800       810       820       830         
pF1KB1 VGLQK--ISHSRSLHKQIRLQVERQEVELPSIEGLIFINIPSWGSGADLWGSDSDTRFEK
        : .   ... ..:.:...:... ..: :::.::.: .::  ::.:  :: . .:  .  
XP_011 YGTKDCLVQECKDLNKKVELELDGERVALPSLEGIIVLNIGYWGGGCRLWEGMGDETYPL
       430       440       450       460       470       480       

     840       850       860       870       880         890       
pF1KB1 PRMDDGLLEVVGVTGVVYMGQVQGGLRSGIRIAQGSYFRVTLLKAT--PVQVDGEPWVQA
        : :::::::::: :  . .:.:  : . .::.:.   :. .:: .  :.:::::::.:.
XP_011 ARHDDGLLEVVGVYGSFHCAQIQVKLANPFRIGQAHTVRL-ILKCSMMPMQVDGEPWAQG
       490       500       510       520        530       540      

       900       910       920       930       940  
pF1KB1 PGHMIISAAGPKVHMLRKAKQKPRRAGTTRDARADAAPAPESDPR
       :  . :.     . .  ...:     ..: :              
XP_011 PCTVTITHKTHAMMLYFSGEQTDDDISSTSDQEDIKATE      
        550       560       570       580           

>>XP_011518725 (OMIM: 601441) PREDICTED: diacylglycerol   (809 aa)
 initn: 638 init1: 307 opt: 832  Z-score: 575.2  bits: 117.6 E(85289): 2.7e-25
Smith-Waterman score: 832; 40.8% identity (68.3% similar) in 375 aa overlap (575-938:163-523)

          550       560       570       580       590       600    
pF1KB1 DVACFAEAERLYMLLKDMAVRGRLLTALVLPDLLHAKLPPDSCPLLVFVNPKSGGLKGRD
                                     : ...    :   :::::::::::: .:  
XP_011 QNTLKASKKKKRASFKRKSSKKGPEEGRWRPFIIRPTPSPLMKPLLVFVNPKSGGNQGAK
            140       150       160       170       180       190  

          610       620       630       640       650       660    
pF1KB1 LLCSFRKLLNPHQVFDLTNGGPLPGLHLFSQVPCFRVLVCGGDGTVGWVLGALEETRYRL
       .. ::   :::.:::::..:::  .:... .:  .:.:.:::::::::.:..:.. : . 
XP_011 IIQSFLWYLNPRQVFDLSQGGPKEALEMYRKVHNLRILACGGDGTVGWILSTLDQLRLK-
            200       210       220       230       240       250  

          670       680       690       700        710       720   
pF1KB1 ACPEPSVAILPLGTGNDLGRVLRWGAGYSGEDPFSVLLS-VDEADAVLMDRWTILLDAH-
         : : ::::::::::::.:.: ::.::. : : : .:: :.:...: .::: .  . . 
XP_011 --PPPPVAILPLGTGNDLARTLNWGGGYTDE-PVSKILSHVEEGNVVQLDRWDLHAEPNP
               260       270       280        290       300        

            730       740       750       760       770       780  
pF1KB1 EAGSAENDTADAEPPKIVQMSNYCGIGIDAELSLDFHQAREEEPGKFTSRLHNKGVYVRV
       :::  . : . ..   .  ..:: ..:.::...:.::..:: .: ::.::..::  :. .
XP_011 EAGPEDRDEGATDRLPLDVFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGT
      310       320       330       340       350       360        

              790       800       810            820       830     
pF1KB1 GLQK--ISHSRSLHKQIRLQVERQEVELPSIEGL-----IFINIPSWGSGADLWGSDSDT
       ...   .. :..: :.::.  . ...  :.:. :     .:.::: . .:.  ::  .. 
XP_011 AFSDFLMGSSKDLAKHIRVVCDGMDLT-PKIQDLKPQCVVFLNIPRYCAGTMPWGHPGEH
      370       380       390        400       410       420       

          840       850       860        870       880       890   
pF1KB1 R-FEKPRMDDGLLEVVGVTGVVYMGQVQ-GGLRSGIRIAQGSYFRVTLLKATPVQVDGEP
       . ::  : ::: :::.: : .. .. .: ::   : :..:     .:  :: ::::::::
XP_011 HDFEPQRHDDGYLEVIGFT-MTSLAALQVGG--HGERLTQCREVVLTTSKAIPVQVDGEP
       430       440        450         460       470       480    

           900       910       920       930       940             
pF1KB1 WVQAPGHMIISAAGPKVHMLRKAKQKPRRAGTTRDARADAAPAPESDPR           
          : ... : :   .. :..:::   ::...    ..:  :.::               
XP_011 CKLAASRIRI-ALRNQATMVQKAK---RRSAAP--LHSDQQPVPEQLRIQVSRVSMHDYE
          490        500          510         520       530        

XP_011 ALHYDKEQLKEASVPLGTVVVPGDSDLELCRAHIERLQQEPDGAGAKSPTCQKLSPKWCF
      540       550       560       570       580       590        




942 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 11:50:39 2016 done: Thu Nov  3 11:50:41 2016
 Total Scan time: 15.290 Total Display time:  0.190

Function used was FASTA [36.3.4 Apr, 2011]
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