Result of FASTA (omim) for pF1KA1788
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KA1788, 411 aa
  1>>>pF1KA1788 411 - 411 aa - 411 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 11.1829+/-0.000433; mu= -6.2929+/- 0.027
 mean_var=442.0762+/-88.639, 0's: 0 Z-trim(123.7): 145  B-trim: 191 in 1/58
 Lambda= 0.060999
 statistics sampled from 43756 (43939) to 43756 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.802), E-opt: 0.2 (0.515), width:  16
 Scan time: 10.010

The best scores are:                                      opt bits E(85289)
NP_068745 (OMIM: 605420,609597,613451,615529) home ( 411) 2817 261.7 2.4e-69
XP_011537084 (OMIM: 601527,613456) PREDICTED: ALX  ( 231)  782 82.3 1.3e-15
NP_008913 (OMIM: 601527,613456) ALX homeobox prote ( 326)  782 82.5 1.7e-15
NP_006483 (OMIM: 136760,606014) homeobox protein a ( 343)  721 77.2 7.2e-14
NP_001263380 (OMIM: 606701) dorsal root ganglia ho ( 263)  422 50.7   5e-06
NP_620689 (OMIM: 300004,300215,300382,300419,30835 ( 562)  418 50.7 1.1e-05
NP_878314 (OMIM: 142993,610092,610093) visual syst ( 361)  396 48.6   3e-05
NP_116142 (OMIM: 605726,610362,610381,613757) reti ( 184)  380 46.9 5.1e-05
NP_001306003 (OMIM: 605726,610362,610381,613757) r ( 230)  380 47.0 5.9e-05
XP_016883326 (OMIM: 122000,148300,605020,614195) P ( 280)  366 45.8 0.00016
NP_001243201 (OMIM: 122000,148300,605020,614195) v ( 301)  366 45.9 0.00017
NP_005020 (OMIM: 107250,602669,610623) pituitary h ( 302)  364 45.7 0.00019
NP_055403 (OMIM: 122000,148300,605020,614195) visu ( 365)  366 45.9 0.00019
NP_001191327 (OMIM: 137600,180500,180550,601542,60 ( 317)  359 45.3 0.00026
NP_001191326 (OMIM: 137600,180500,180550,601542,60 ( 317)  359 45.3 0.00026
NP_700475 (OMIM: 137600,180500,180550,601542,60422 ( 317)  359 45.3 0.00026
NP_003915 (OMIM: 209880,603851,613013) paired meso ( 314)  357 45.1  0.0003
NP_001290437 (OMIM: 612019) intestine-specific hom ( 245)  350 44.4 0.00038
NP_008833 (OMIM: 167420,202650) paired mesoderm ho ( 217)  345 43.9 0.00048
NP_038463 (OMIM: 601881,611038) retinal homeobox p ( 346)  349 44.4 0.00052
NP_000316 (OMIM: 137600,180500,180550,601542,60422 ( 324)  347 44.2 0.00056
XP_006711451 (OMIM: 167420,202650) PREDICTED: pair ( 198)  341 43.5 0.00057
NP_005160 (OMIM: 602078,602753) paired mesoderm ho ( 284)  344 43.9 0.00061
NP_073207 (OMIM: 167420,202650) paired mesoderm ho ( 245)  342 43.6 0.00062
NP_852126 (OMIM: 122880,148820,193500,268220,60659 ( 403)  347 44.3 0.00065
NP_852125 (OMIM: 122880,148820,193500,268220,60659 ( 407)  347 44.3 0.00065
XP_011530329 (OMIM: 137600,180500,180550,601542,60 ( 271)  342 43.7 0.00067
NP_700476 (OMIM: 137600,180500,180550,601542,60422 ( 271)  342 43.7 0.00067
NP_001191328 (OMIM: 137600,180500,180550,601542,60 ( 271)  342 43.7 0.00067
NP_002644 (OMIM: 119800,186550,602149) pituitary h ( 314)  343 43.8  0.0007
NP_852122 (OMIM: 122880,148820,193500,268220,60659 ( 479)  347 44.4 0.00073
NP_001120838 (OMIM: 122880,148820,193500,268220,60 ( 483)  347 44.4 0.00073
NP_852123 (OMIM: 122880,148820,193500,268220,60659 ( 484)  347 44.4 0.00073
NP_852124 (OMIM: 122880,148820,193500,268220,60659 ( 505)  347 44.4 0.00075
NP_039236 (OMIM: 167410,268220) paired box protein ( 518)  343 44.1 0.00098
NP_057391 (OMIM: 604675) paired mesoderm homeobox  ( 253)  334 43.0   0.001
NP_001128726 (OMIM: 167410,268220) paired box prot ( 505)  339 43.7  0.0012
NP_002575 (OMIM: 167410,268220) paired box protein ( 520)  339 43.7  0.0013
NP_115485 (OMIM: 604529) homeobox protein orthoped ( 325)  332 42.9  0.0014
XP_016870292 (OMIM: 604675) PREDICTED: paired meso ( 193)  325 42.0  0.0015
NP_703149 (OMIM: 300154) homeobox protein ESX1 [Ho ( 406)  329 42.7  0.0019
NP_006875 (OMIM: 602504) short stature homeobox pr ( 331)  326 42.4   0.002
NP_003021 (OMIM: 602504) short stature homeobox pr ( 355)  326 42.4  0.0021
NP_001297088 (OMIM: 106210,120430,136520,148190,16 ( 401)  327 42.6  0.0022
NP_001245394 (OMIM: 106210,120430,136520,148190,16 ( 422)  325 42.4  0.0025
NP_000271 (OMIM: 106210,120430,136520,148190,16555 ( 422)  325 42.4  0.0025
NP_001245393 (OMIM: 106210,120430,136520,148190,16 ( 422)  325 42.4  0.0025
NP_001121084 (OMIM: 106210,120430,136520,148190,16 ( 422)  325 42.4  0.0025
NP_001245391 (OMIM: 106210,120430,136520,148190,16 ( 436)  325 42.4  0.0026
NP_001595 (OMIM: 106210,120430,136520,148190,16555 ( 436)  325 42.4  0.0026


>>NP_068745 (OMIM: 605420,609597,613451,615529) homeobox  (411 aa)
 initn: 2817 init1: 2817 opt: 2817  Z-score: 1365.9  bits: 261.7 E(85289): 2.4e-69
Smith-Waterman score: 2817; 100.0% identity (100.0% similar) in 411 aa overlap (1-411:1-411)

               10        20        30        40        50        60
pF1KA1 MNAETCVSYCESPAAAMDAYYSPVSQSREGSSPFRAFPGGDKFGTTFLSAAAKAQGFGDA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 MNAETCVSYCESPAAAMDAYYSPVSQSREGSSPFRAFPGGDKFGTTFLSAAAKAQGFGDA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA1 KSRARYGAGQQDLATPLESGAGARGSFNKFQPQPSTPQPQPPPQPQPQQQQPQPQPPAQP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 KSRARYGAGQQDLATPLESGAGARGSFNKFQPQPSTPQPQPPPQPQPQQQQPQPQPPAQP
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA1 HLYLQRGACKTPPDGSLKLQEGSSGHSAALQVPCYAKESSLGEPELPPDSDTVGMDSSYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 HLYLQRGACKTPPDGSLKLQEGSSGHSAALQVPCYAKESSLGEPELPPDSDTVGMDSSYL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA1 SVKEAGVKGPQDRASSDLPSPLEKADSESNKGKKRRNRTTFTSYQLEELEKVFQKTHYPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 SVKEAGVKGPQDRASSDLPSPLEKADSESNKGKKRRNRTTFTSYQLEELEKVFQKTHYPD
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA1 VYAREQLAMRTDLTEARVQVWFQNRRAKWRKRERFGQMQQVRTHFSTAYELPLLTRAENY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 VYAREQLAMRTDLTEARVQVWFQNRRAKWRKRERFGQMQQVRTHFSTAYELPLLTRAENY
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA1 AQIQNPSWLGNNGAASPVPACVVPCDPVPACMSPHAHPPGSGASSVTDFLSVSGAGSHVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 AQIQNPSWLGNNGAASPVPACVVPCDPVPACMSPHAHPPGSGASSVTDFLSVSGAGSHVG
              310       320       330       340       350       360

              370       380       390       400       410 
pF1KA1 QTHMGSLFGAASLSPGLNGYELNGEPDRKTSSIAALRMKAKEHSAAISWAT
       :::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 QTHMGSLFGAASLSPGLNGYELNGEPDRKTSSIAALRMKAKEHSAAISWAT
              370       380       390       400       410 

>>XP_011537084 (OMIM: 601527,613456) PREDICTED: ALX home  (231 aa)
 initn: 697 init1: 579 opt: 782  Z-score: 401.1  bits: 82.3 E(85289): 1.3e-15
Smith-Waterman score: 782; 52.5% identity (78.6% similar) in 238 aa overlap (175-410:1-230)

          150       160       170       180       190       200    
pF1KA1 GHSAALQVPCYAKESSLGEPELPPDSDTVGMDSSYLSVKEAGVKGPQDRASSDLPSPLEK
                                     ::.   :.. . ::: :..  ..:    .:
XP_011                               MDNCN-SLRMSPVKGMQEK--GELDELGDK
                                              10          20       

          210       220       230       240       250       260    
pF1KA1 ADSESNKGKKRRNRTTFTSYQLEELEKVFQKTHYPDVYAREQLAMRTDLTEARVQVWFQN
        ::. ...::::.:::::: ::::::::::::::::::.:::::.::.::::::::::::
XP_011 CDSNVSSSKKRRHRTTFTSLQLEELEKVFQKTHYPDVYVREQLALRTELTEARVQVWFQN
        30        40        50        60        70        80       

          270       280       290       300       310       320    
pF1KA1 RRAKWRKRERFGQMQQVRTHFSTAYELPLLTRAENYAQIQNPSWLGNNGAASPVPACVVP
       ::::::::::.::.::...::...:.. .: :...: ::::  : :: ...: : .:..:
XP_011 RRAKWRKRERYGQIQQAKSHFAATYDISVLPRTDSYPQIQNNLWAGNASGGSVVTSCMLP
        90       100       110       120       130       140       

          330       340       350       360       370       380    
pF1KA1 CDPVPACMSPHAHPPGSGASSVTDFLSVSGAGSHVGQTHMGSLFGAASLSPGLNGYELNG
        : . .::.:..: : .  :: : : . ..  :::    ....:  . :. . ::. .. 
XP_011 RD-TSSCMTPYSHSPRTD-SSYTGFSNHQNQFSHVP---LNNFFTDSLLTGATNGHAFET
        150       160        170       180          190       200  

            390       400       410 
pF1KA1 EPD--RKTSSIAALRMKAKEHSAAISWAT
       .:.  :..::::.::::::::.: :::: 
XP_011 KPEFERRSSSIAVLRMKAKEHTANISWAM
            210       220       230 

>>NP_008913 (OMIM: 601527,613456) ALX homeobox protein 1  (326 aa)
 initn: 697 init1: 579 opt: 782  Z-score: 399.3  bits: 82.5 E(85289): 1.7e-15
Smith-Waterman score: 782; 52.5% identity (78.6% similar) in 238 aa overlap (175-410:96-325)

          150       160       170       180       190       200    
pF1KA1 GHSAALQVPCYAKESSLGEPELPPDSDTVGMDSSYLSVKEAGVKGPQDRASSDLPSPLEK
                                     ::.   :.. . ::: :..  ..:    .:
NP_008 ERTSPCQDSSVNYGITKVEGQPLHTELNRAMDNCN-SLRMSPVKGMQEK--GELDELGDK
          70        80        90       100        110         120  

          210       220       230       240       250       260    
pF1KA1 ADSESNKGKKRRNRTTFTSYQLEELEKVFQKTHYPDVYAREQLAMRTDLTEARVQVWFQN
        ::. ...::::.:::::: ::::::::::::::::::.:::::.::.::::::::::::
NP_008 CDSNVSSSKKRRHRTTFTSLQLEELEKVFQKTHYPDVYVREQLALRTELTEARVQVWFQN
            130       140       150       160       170       180  

          270       280       290       300       310       320    
pF1KA1 RRAKWRKRERFGQMQQVRTHFSTAYELPLLTRAENYAQIQNPSWLGNNGAASPVPACVVP
       ::::::::::.::.::...::...:.. .: :...: ::::  : :: ...: : .:..:
NP_008 RRAKWRKRERYGQIQQAKSHFAATYDISVLPRTDSYPQIQNNLWAGNASGGSVVTSCMLP
            190       200       210       220       230       240  

          330       340       350       360       370       380    
pF1KA1 CDPVPACMSPHAHPPGSGASSVTDFLSVSGAGSHVGQTHMGSLFGAASLSPGLNGYELNG
        : . .::.:..: : .  :: : : . ..  :::    ....:  . :. . ::. .. 
NP_008 RD-TSSCMTPYSHSPRTD-SSYTGFSNHQNQFSHVP---LNNFFTDSLLTGATNGHAFET
             250        260       270          280       290       

            390       400       410 
pF1KA1 EPD--RKTSSIAALRMKAKEHSAAISWAT
       .:.  :..::::.::::::::.: :::: 
NP_008 KPEFERRSSSIAVLRMKAKEHTANISWAM
       300       310       320      

>>NP_006483 (OMIM: 136760,606014) homeobox protein arist  (343 aa)
 initn: 681 init1: 583 opt: 721  Z-score: 370.0  bits: 77.2 E(85289): 7.2e-14
Smith-Waterman score: 731; 41.1% identity (63.1% similar) in 360 aa overlap (76-411:8-343)

          50        60        70        80        90       100     
pF1KA1 TFLSAAAKAQGFGDAKSRARYGAGQQDLATPLESGAGARGSFNKFQPQPSTPQPQPPPQP
                                     :.. :  : : .     .:  : ::  :  
NP_006                        MDPEHCAPFRVGP-APGPYVASGDEP--PGPQGTPAA
                                      10         20          30    

         110       120                 130        140          150 
pF1KA1 QPQQQQPQPQPPAQPHLYLQRGAC----------KTPPDGSLK-LQEG---SSGHSAALQ
        :. .   : ::  :.:  .  ::            ::   :. :  :   ..::    .
NP_006 APHLH---PAPPRGPRL-TRFPACGPLEPYLPEPAKPPAKYLQDLGPGPALNGGH--FYE
              40         50        60        70        80          

             160          170        180       190        200      
pF1KA1 VPCYAKESS---LGEPELPPDSDTVGMDS-SYLSVKEAGVKGPQDRASSDLP-SPL--EK
        :  :.:..    . :.:: :      :. : :.    :  ::   ::  :: ::   ..
NP_006 GPAEAEEKTSKAASFPQLPLDCRGGPRDGPSNLQ----GSPGPC-LASLHLPLSPGLPDS
       90       100       110       120            130       140   

          210       220       230       240       250       260    
pF1KA1 ADSESNKGKKRRNRTTFTSYQLEELEKVFQKTHYPDVYAREQLAMRTDLTEARVQVWFQN
        .  .::.:::::::::...::::::::::::::::::::::::.:::::::::::::::
NP_006 MELAKNKSKKRRNRTTFSTFQLEELEKVFQKTHYPDVYAREQLALRTDLTEARVQVWFQN
           150       160       170       180       190       200   

          270       280       290       300       310       320    
pF1KA1 RRAKWRKRERFGQMQQVRTHFSTAYELPLLTRAENYAQIQNPSWLGNNGAASPVPACVVP
       ::::::::::.:..:. :. :..::.. .: :.... :.::  : .. :..::   :.: 
NP_006 RRAKWRKRERYGKIQEGRNPFTAAYDISVLPRTDSHPQLQNSLW-ASPGSGSPGGPCLVS
           210       220       230       240        250       260  

          330        340       350       360       370         380 
pF1KA1 CDPVPA-CMSPHAHPPGSGASSVTDFLSVSGAGSHVGQTHMGSLFGAASLSPGLNG--YE
        . .:. ::::..:: ::    :. :..: . ..    .: : ...  .. : :.:  .:
NP_006 PEGIPSPCMSPYSHPHGS----VAGFMGVPAPSA----AHPG-IYSIHGFPPTLGGHSFE
            270       280           290            300       310   

             390       400       410 
pF1KA1 LNGEPDRKTSSIAALRMKAKEHSAAISWAT
        ... : :. :...::.: ::  . ..:.:
NP_006 PSSDGDYKSPSLVSLRVKPKEPPGLLNWTT
           320       330       340   

>>NP_001263380 (OMIM: 606701) dorsal root ganglia homeob  (263 aa)
 initn: 430 init1: 330 opt: 422  Z-score: 229.2  bits: 50.7 E(85289): 5e-06
Smith-Waterman score: 422; 42.2% identity (62.3% similar) in 199 aa overlap (213-407:32-220)

            190       200       210       220       230       240  
pF1KA1 KEAGVKGPQDRASSDLPSPLEKADSESNKGKKRRNRTTFTSYQLEELEKVFQKTHYPDVY
                                     :.::::::::  ::: :: :: .::::::.
NP_001 FYFHCPPQLEGTATFGNHSSGDFDDGFLRRKQRRNRTTFTLQQLEALEAVFAQTHYPDVF
              10        20        30        40        50        60 

            250       260       270       280       290       300  
pF1KA1 AREQLAMRTDLTEARVQVWFQNRRAKWRKRERFGQMQQVRTHFSTAYELPLLTRAENYAQ
       .::.:::. .::::::::::::::::::: :: .. :.  ..   :   :  .:  :   
NP_001 TREELAMKINLTEARVQVWFQNRRAKWRKTERGASDQEPGAKEPMAEVTPPPVRNINSPP
              70        80        90       100       110       120 

            310         320        330       340       350         
pF1KA1 IQNPSWLGNNG--AASPVPACVVPCDPV-PACMSPHAHPPGSGASSVTDFLSVSGAGSHV
         . .   ...  : . .   : :  :  :.:.      ::.  ...:     . : :::
NP_001 PGDQARSKKEALEAQQSLGRTVGPAGPFFPSCL------PGTLLNTAT----YAQALSHV
             130       140       150             160           170 

     360       370        380       390       400       410        
pF1KA1 GQTHMGSLFGAASLSP-GLNGYELNGEPDRKTSSIAALRMKAKEHSAAISWAT       
       .. . : : .    .: ::.     :  . .:.:.:.:::::.::: :.           
NP_001 ASLKGGPLCSCCVPDPMGLSFLPTYGCQSNRTASVATLRMKAREHSEAVLQSANLLPSTS
             180       190       200       210       220       230 

NP_001 SSPGPVAKPAPPDGSQEKTSPTKEQSEAEKSV
             240       250       260   

>>NP_620689 (OMIM: 300004,300215,300382,300419,308350,30  (562 aa)
 initn: 537 init1: 366 opt: 418  Z-score: 223.3  bits: 50.7 E(85289): 1.1e-05
Smith-Waterman score: 485; 41.6% identity (61.4% similar) in 267 aa overlap (173-408:282-547)

            150       160       170       180       190        200 
pF1KA1 SSGHSAALQVPCYAKESSLGEPELPPDSDTVGMDSSYLSVKEAGVKGPQDRASSD-LPSP
                                     :. ... :: ::  .  :.:  ..:   : 
NP_620 LEDDARALLKEPRRCPVAATGAVAAAAAAAVATEGGELSPKEELLLHPEDAEGKDGEDSV
             260       270       280       290       300       310 

             210           220       230       240       250       
pF1KA1 LEKADSESNKG----KKRRNRTTFTSYQLEELEKVFQKTHYPDVYAREQLAMRTDLTEAR
         .: :.:..:    :.:: :::::::::::::..:::::::::..::.:::: ::::::
NP_620 CLSAGSDSEEGLLKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEAR
             320       330       340       350       360       370 

       260       270        280           290       300       310  
pF1KA1 VQVWFQNRRAKWRKRERFG-QMQQVRTHF----STAYELPLLTRAENYAQIQNPSWLGNN
       ::::::::::::::::. : : .     :    :... :     :  .   ..:.  .  
NP_620 VQVWFQNRRAKWRKREKAGAQTHPPGLPFPGPLSATHPLSPYLDASPFPP-HHPALDSAW
             380       390       400       410       420        430

            320          330       340           350       360     
pF1KA1 GAASPVPACVVPCDPVP---ACMSPHAHPPGS----GASSVTDFLSVSGAGSHVGQTH--
        ::. . : . :  : :   : . : . : :     ::.       .: : ... .:   
NP_620 TAAAAAAAAAFPSLPPPPGSASLPPSGAPLGLSTFLGAAVFRHPAFISPAFGRLFSTMAP
              440       450       460       470       480       490

           370           380               390       400       410 
pF1KA1 MGSLFGAASL----SPGLNGYELNG---EP-----DRKTSSIAALRMKAKEHSAAISWAT
       . :   ::.:    .:...:   .:   .:     ::..:::::::.:::::.: ..   
NP_620 LTSASTAAALLRQPTPAVEGAVASGALADPATAAADRRASSIAALRLKAKEHAAQLTQLN
              500       510       520       530       540       550

NP_620 ILPGTSTGKEVC
              560  

>>NP_878314 (OMIM: 142993,610092,610093) visual system h  (361 aa)
 initn: 452 init1: 355 opt: 396  Z-score: 215.2  bits: 48.6 E(85289): 3e-05
Smith-Waterman score: 402; 38.2% identity (61.4% similar) in 220 aa overlap (58-274:6-208)

        30        40        50        60        70        80       
pF1KA1 REGSSPFRAFPGGDKFGTTFLSAAAKAQGFGDAKSRARYGAGQQDLATPLESGAGARGSF
                                     :.: :. .    .. .:    .:: :: . 
NP_878                          MTGKAGEALSKPK----SETVAKSTSGGAPARCT-
                                        10            20        30 

        90       100       110       120       130       140       
pF1KA1 NKFQPQPSTPQPQPPPQPQPQQQQPQPQPPAQPHLYLQRGACKTPPDGSLKLQEGSSGHS
         :  :      . ::. .:.       :    ::   :.. .    :.. :  : .:  
NP_878 -GFGIQEILGLNKEPPSSHPRAALDGLAPG---HLLAARSVLSPAGVGGMGLL-GPGGLP
                40        50           60        70         80     

       150       160          170       180       190       200    
pF1KA1 AALQVPCYAKESSLGEPE---LPPDSDTVGMDSSYLSVKEAGVKGPQDRASSDLPSPLEK
       .    : . .   :..:.   : :    .:  :. :...... .  .: .:::     ..
NP_878 GFYTQPTFLE--VLSDPQSVHLQP----LGRASGPLDTSQTASSDSEDVSSSDRKMS-KS
          90         100           110       120       130         

          210       220       230       240       250       260    
pF1KA1 ADSESNKGKKRRNRTTFTSYQLEELEKVFQKTHYPDVYAREQLAMRTDLTEARVQVWFQN
       : ....: ::::.:: :::::::::::.:...:::::::::.:::.:.: : :.::::::
NP_878 ALNQTKKRKKRRHRTIFTSYQLEELEKAFNEAHYPDVYAREMLAMKTELPEDRIQVWFQN
      140       150       160       170       180       190        

          270       280       290       300       310       320    
pF1KA1 RRAKWRKRERFGQMQQVRTHFSTAYELPLLTRAENYAQIQNPSWLGNNGAASPVPACVVP
       :::::::::.                                                  
NP_878 RRAKWRKREKCWGRSSVMAEYGLYGAMVRHSIPLPESILKSAKDGIMDSCAPWLLGMHKK
      200       210       220       230       240       250        

>>NP_116142 (OMIM: 605726,610362,610381,613757) retina a  (184 aa)
 initn: 361 init1: 327 opt: 380  Z-score: 211.2  bits: 46.9 E(85289): 5.1e-05
Smith-Waterman score: 380; 46.7% identity (70.4% similar) in 135 aa overlap (208-339:21-153)

       180       190       200       210       220       230       
pF1KA1 SYLSVKEAGVKGPQDRASSDLPSPLEKADSESNKGKKRRNRTTFTSYQLEELEKVFQKTH
                                     :. : :.::::::::.:::..::..:. .:
NP_116           MFLSPGEGPATEGGGLGPGEEAPKKKHRRNRTTFTTYQLHQLERAFEASH
                         10        20        30        40        50

       240       250       260       270         280       290     
pF1KA1 YPDVYAREQLAMRTDLTEARVQVWFQNRRAKWRKRERF--GQMQQVRTHFSTAYELPLLT
       :::::.::.:: .. : :.::::::::::::::..::.  :.   .  ..  :  ::. .
NP_116 YPDVYSREELAAKVHLPEVRVQVWFQNRRAKWRRQERLESGSGAVAAPRLPEAPALPF-A
               60        70        80        90       100          

         300       310        320       330       340       350    
pF1KA1 RAENYAQIQNPSWLGNNGAASP-VPACVVPCDPVPACMSPHAHPPGSGASSVTDFLSVSG
       :   ..   .: ::: .  : : .:  . :   . : ..:::  :               
NP_116 RPPAMSLPLEP-WLGPGPPAVPGLPRLLGPGPGLQASFGPHAFAPTFADGFALEEASLRL
     110       120        130       140       150       160        

          360       370       380       390       400       410 
pF1KA1 AGSHVGQTHMGSLFGAASLSPGLNGYELNGEPDRKTSSIAALRMKAKEHSAAISWAT
                                                                
NP_116 LAKEHAQALDRAWPPA                                         
      170       180                                             

>>NP_001306003 (OMIM: 605726,610362,610381,613757) retin  (230 aa)
 initn: 383 init1: 327 opt: 380  Z-score: 210.0  bits: 47.0 E(85289): 5.9e-05
Smith-Waterman score: 397; 39.8% identity (63.3% similar) in 196 aa overlap (147-339:20-199)

        120       130       140       150       160       170      
pF1KA1 PAQPHLYLQRGACKTPPDGSLKLQEGSSGHSAALQVPCYAKESSLGEPELPPDSDTVGMD
                                     : ::..:  .   ... : .:  :  ::  
NP_001            MPAPVEGTDFPGAGRQAWGSPALSLP--VAPPAVSPPSVPLPSHQVG--
                          10        20          30        40       

        180       190       200       210       220       230      
pF1KA1 SSYLSVKEAGVKGPQDRASSDLPSPLEKADSESNKGKKRRNRTTFTSYQLEELEKVFQKT
       . .::  :    ::  ....  :.       :. : :.::::::::.:::..::..:. .
NP_001 AMFLSPGE----GPATEGGGLGPG------EEAPKKKHRRNRTTFTTYQLHQLERAFEAS
          50            60              70        80        90     

        240       250       260       270         280       290    
pF1KA1 HYPDVYAREQLAMRTDLTEARVQVWFQNRRAKWRKRERF--GQMQQVRTHFSTAYELPLL
       ::::::.::.:: .. : :.::::::::::::::..::.  :.   .  ..  :  ::. 
NP_001 HYPDVYSREELAAKVHLPEVRVQVWFQNRRAKWRRQERLESGSGAVAAPRLPEAPALPF-
         100       110       120       130       140       150     

          300       310        320       330       340       350   
pF1KA1 TRAENYAQIQNPSWLGNNGAASP-VPACVVPCDPVPACMSPHAHPPGSGASSVTDFLSVS
       .:   ..   .: ::: .  : : .:  . :   . : ..:::  :              
NP_001 ARPPAMSLPLEP-WLGPGPPAVPGLPRLLGPGPGLQASFGPHAFAPTFADGFALEEASLR
          160        170       180       190       200       210   

           360       370       380       390       400       410 
pF1KA1 GAGSHVGQTHMGSLFGAASLSPGLNGYELNGEPDRKTSSIAALRMKAKEHSAAISWAT
                                                                 
NP_001 LLAKEHAQALDRAWPPA                                         
           220       230                                         

>>XP_016883326 (OMIM: 122000,148300,605020,614195) PREDI  (280 aa)
 initn: 402 init1: 339 opt: 366  Z-score: 202.3  bits: 45.8 E(85289): 0.00016
Smith-Waterman score: 366; 42.8% identity (58.2% similar) in 194 aa overlap (97-276:44-227)

         70        80        90       100       110       120      
pF1KA1 GAGQQDLATPLESGAGARGSFNKFQPQPSTPQPQPPPQPQPQQQQPQPQPPAQPHL---Y
                                     : :  : : .  .  :   :   : :    
XP_016 SRALVPGGSPRGSRPRGFAITDLLGLEAELPAPAGPGQGSGCEG-PAVAPCPGPGLDGSS
            20        30        40        50         60        70  

           130       140        150       160       170       180  
pF1KA1 LQRGACKTPPDGSLKLQEG-SSGHSAALQVPCYAKESSLGEPELPPDSDTVGMDSSYLSV
       : :::    : : : :  : ..   :: ..::    .    : ::: .   .  .     
XP_016 LARGAL---PLG-LGLLCGFGTQPPAAARAPCLLLADV---PFLPPRGPEPA--APLAPS
                80         90       100          110         120   

            190           200            210       220       230   
pF1KA1 KEAGVKGPQDRA----SSDLPSPLE-----KADSESNKGKKRRNRTTFTSYQLEELEKVF
       .   . : : :.    .::  :  :     ::.   .: ::::.::.::..:::::::.:
XP_016 RPPPALGRQKRSDSVSTSDEDSQSEDRNDLKASPTLGKRKKRRHRTVFTAHQLEELEKAF
           130       140       150       160       170       180   

           240       250       260       270        280       290  
pF1KA1 QKTHYPDVYAREQLAMRTDLTEARVQVWFQNRRAKWRKRE-RFGQMQQVRTHFSTAYELP
       ...:::::::::.::..:.: : :.::::::::::::::: :.:                
XP_016 SEAHYPDVYAREMLAVKTELPEDRIQVWFQNRRAKWRKREKRWGGSSVMAEYGLYGAMVR
           190       200       210       220       230       240   

            300       310       320       330       340       350  
pF1KA1 LLTRAENYAQIQNPSWLGNNGAASPVPACVVPCDPVPACMSPHAHPPGSGASSVTDFLSV
                                                                   
XP_016 HCIPLPDSVLNSAEGGLLGSCAPWLLEGETLGCREMK                       
           250       260       270       280                       




411 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 11:21:55 2016 done: Thu Nov  3 11:21:57 2016
 Total Scan time: 10.010 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]
Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.com