Result of FASTA (omim) for pF1KA1042
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KA1042, 953 aa
  1>>>pF1KA1042 953 - 953 aa - 953 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 10.5242+/-0.000425; mu= -3.3642+/- 0.026
 mean_var=286.5623+/-58.635, 0's: 0 Z-trim(119.8): 39  B-trim: 555 in 3/55
 Lambda= 0.075764
 statistics sampled from 34208 (34252) to 34208 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.732), E-opt: 0.2 (0.402), width:  16
 Scan time: 16.200

The best scores are:                                      opt bits E(85289)
NP_001036111 (OMIM: 608112) trafficking kinesin-bi ( 953) 6206 692.8 2.2e-198
XP_005265015 (OMIM: 608112) PREDICTED: trafficking ( 879) 5547 620.7  1e-176
XP_005265017 (OMIM: 608112) PREDICTED: trafficking ( 712) 4460 501.8  5e-141
XP_005265019 (OMIM: 608112) PREDICTED: trafficking ( 666) 4231 476.8 1.6e-133
XP_006713092 (OMIM: 608112) PREDICTED: trafficking ( 666) 4231 476.8 1.6e-133
XP_011531791 (OMIM: 608112) PREDICTED: trafficking ( 664) 4226 476.2 2.4e-133
NP_001252537 (OMIM: 608112) trafficking kinesin-bi ( 744) 4220 475.6 4.1e-133
XP_016861401 (OMIM: 608112) PREDICTED: trafficking ( 758) 4220 475.6 4.1e-133
XP_016861395 (OMIM: 608112) PREDICTED: trafficking (1022) 4220 475.7 5.2e-133
XP_016861402 (OMIM: 608112) PREDICTED: trafficking ( 691) 4090 461.4 7.2e-129
XP_005265020 (OMIM: 608112) PREDICTED: trafficking ( 645) 4089 461.3 7.4e-129
XP_006713093 (OMIM: 608112) PREDICTED: trafficking ( 645) 4089 461.3 7.4e-129
XP_005265013 (OMIM: 608112) PREDICTED: trafficking ( 932) 4092 461.7 7.9e-129
XP_006713094 (OMIM: 608112) PREDICTED: trafficking ( 643) 4079 460.2 1.6e-128
NP_001252538 (OMIM: 608112) trafficking kinesin-bi ( 670) 3561 403.5 1.8e-111
NP_055780 (OMIM: 608112) trafficking kinesin-bindi ( 686) 3561 403.6 1.8e-111
XP_016861397 (OMIM: 608112) PREDICTED: trafficking ( 925) 3561 403.6 2.3e-111
XP_016861396 (OMIM: 608112) PREDICTED: trafficking ( 941) 3561 403.6 2.4e-111
XP_016861398 (OMIM: 608112) PREDICTED: trafficking ( 895) 3504 397.4 1.7e-109
XP_016861399 (OMIM: 608112) PREDICTED: trafficking ( 858) 3433 389.6 3.6e-107
XP_016861400 (OMIM: 608112) PREDICTED: trafficking ( 828) 3376 383.4 2.6e-105
NP_001252539 (OMIM: 608112) trafficking kinesin-bi ( 556) 3059 348.6 5.1e-95
XP_011509992 (OMIM: 607334) PREDICTED: trafficking ( 914) 1815 212.8 6.5e-54
NP_055864 (OMIM: 607334) trafficking kinesin-bindi ( 914) 1815 212.8 6.5e-54
XP_016860261 (OMIM: 607334) PREDICTED: trafficking ( 703) 1175 142.8   6e-33
NP_817084 (OMIM: 600947) huntingtin-associated pro ( 619)  259 42.6  0.0075


>>NP_001036111 (OMIM: 608112) trafficking kinesin-bindin  (953 aa)
 initn: 6206 init1: 6206 opt: 6206  Z-score: 3682.5  bits: 692.8 E(85289): 2.2e-198
Smith-Waterman score: 6206; 100.0% identity (100.0% similar) in 953 aa overlap (1-953:1-953)

               10        20        30        40        50        60
pF1KA1 MALVFQFGQPVRAQPLPGLCHGKLIRTNACDVCNSTDLPEVEIISLLEEQLPHYKLRADT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MALVFQFGQPVRAQPLPGLCHGKLIRTNACDVCNSTDLPEVEIISLLEEQLPHYKLRADT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA1 IYGYDHDDWLHTPLISPDANIDLTTEQIEETLKYFLLCAERVGQMTKTYNDIDAVTRLLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IYGYDHDDWLHTPLISPDANIDLTTEQIEETLKYFLLCAERVGQMTKTYNDIDAVTRLLE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA1 EKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIREEVSQLRHELSMKDELLQFYTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIREEVSQLRHELSMKDELLQFYTS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA1 AAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQKKLKDLEEENVVLRSEASQLKTETIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQKKLKDLEEENVVLRSEASQLKTETIT
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA1 YEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQQEEITHLLSQIVDLQKKAKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQQEEITHLLSQIVDLQKKAKA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA1 CAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELKNLRNKTMPNTTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELKNLRNKTMPNTTS
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA1 RRYHSLGLFPMDSLAAEIEGTMRKELQLEEAESPDITHQKRVFETVRNINQVVKQRSLTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRYHSLGLFPMDSLAAEIEGTMRKELQLEEAESPDITHQKRVFETVRNINQVVKQRSLTP
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA1 SPMNIPGSNQSSAMNSLLSSCVSTPRSSFYGSDIGNVVLDNKTNSIILETEAADLGNDER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPMNIPGSNQSSAMNSLLSSCVSTPRSSFYGSDIGNVVLDNKTNSIILETEAADLGNDER
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA1 SKKPGTPGTPGSHDLETALRRLSLRRENYLSERRFFEEEQERKLQELAEKGELRSGSLTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKKPGTPGTPGSHDLETALRRLSLRRENYLSERRFFEEEQERKLQELAEKGELRSGSLTP
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA1 TESIMSLGTHSRFSEFTGFSGMSFSSRSYLPEKLQIVKPLEGSATLHHWQQLAQPHLGGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TESIMSLGTHSRFSEFTGFSGMSFSSRSYLPEKLQIVKPLEGSATLHHWQQLAQPHLGGI
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA1 LDPRPGVVTKGFRTLDVDLDEVYCLNDFEEDDTGDHISLPRLATSTPVQHPETSAHHPGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDPRPGVVTKGFRTLDVDLDEVYCLNDFEEDDTGDHISLPRLATSTPVQHPETSAHHPGK
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA1 CMSQTNSTFTFTTCRILHPSDELTRVTPSLNSAPTPACGSTSHLKSTPVATPCTPRRLSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CMSQTNSTFTFTTCRILHPSDELTRVTPSLNSAPTPACGSTSHLKSTPVATPCTPRRLSL
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA1 AESFTNTRESTTTMSTSLGLVWLLKERGISAAVYDPQSWDRAGRGSLLHSYTPKMAVIPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AESFTNTRESTTTMSTSLGLVWLLKERGISAAVYDPQSWDRAGRGSLLHSYTPKMAVIPS
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA1 TPPNSPMQTPTSSPPSFEFKCTSPPYDNFLASKPASSILREVREKNVRSSESQTDVSVSN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPPNSPMQTPTSSPPSFEFKCTSPPYDNFLASKPASSILREVREKNVRSSESQTDVSVSN
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA1 LNLVDKVRRFGVAKVVNSGRAHVPTLTEEQGPLLCGPPGPAPALVPRGLVPEGLPLRCPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNLVDKVRRFGVAKVVNSGRAHVPTLTEEQGPLLCGPPGPAPALVPRGLVPEGLPLRCPT
              850       860       870       880       890       900

              910       920       930       940       950   
pF1KA1 VTSAIGGLQLNSGIRRNRSFPTMVGSSMQMKAPVTLTSGILMGAKLSKQTSLR
       :::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTSAIGGLQLNSGIRRNRSFPTMVGSSMQMKAPVTLTSGILMGAKLSKQTSLR
              910       920       930       940       950   

>>XP_005265015 (OMIM: 608112) PREDICTED: trafficking kin  (879 aa)
 initn: 5547 init1: 5547 opt: 5547  Z-score: 3293.7  bits: 620.7 E(85289): 1e-176
Smith-Waterman score: 5547; 99.9% identity (100.0% similar) in 858 aa overlap (96-953:22-879)

          70        80        90       100       110       120     
pF1KA1 HDDWLHTPLISPDANIDLTTEQIEETLKYFLLCAERVGQMTKTYNDIDAVTRLLEEKERD
                                     .:::::::::::::::::::::::::::::
XP_005          MQKFIEADYYELDWYYEECSDVLCAERVGQMTKTYNDIDAVTRLLEEKERD
                        10        20        30        40        50 

         130       140       150       160       170       180     
pF1KA1 LELAARIGQSLLKKNKTLTERNELLEEQVEHIREEVSQLRHELSMKDELLQFYTSAAEES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LELAARIGQSLLKKNKTLTERNELLEEQVEHIREEVSQLRHELSMKDELLQFYTSAAEES
              60        70        80        90       100       110 

         190       200       210       220       230       240     
pF1KA1 EPESVCSTPLKRNESSSSVQNYFHLDSLQKKLKDLEEENVVLRSEASQLKTETITYEEKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EPESVCSTPLKRNESSSSVQNYFHLDSLQKKLKDLEEENVVLRSEASQLKTETITYEEKE
             120       130       140       150       160       170 

         250       260       270       280       290       300     
pF1KA1 QQLVNDCVKELRDANVQIASISEELAKKTEDAARQQEEITHLLSQIVDLQKKAKACAVEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QQLVNDCVKELRDANVQIASISEELAKKTEDAARQQEEITHLLSQIVDLQKKAKACAVEN
             180       190       200       210       220       230 

         310       320       330       340       350       360     
pF1KA1 EELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELKNLRNKTMPNTTSRRYHS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELKNLRNKTMPNTTSRRYHS
             240       250       260       270       280       290 

         370       380       390       400       410       420     
pF1KA1 LGLFPMDSLAAEIEGTMRKELQLEEAESPDITHQKRVFETVRNINQVVKQRSLTPSPMNI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LGLFPMDSLAAEIEGTMRKELQLEEAESPDITHQKRVFETVRNINQVVKQRSLTPSPMNI
             300       310       320       330       340       350 

         430       440       450       460       470       480     
pF1KA1 PGSNQSSAMNSLLSSCVSTPRSSFYGSDIGNVVLDNKTNSIILETEAADLGNDERSKKPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PGSNQSSAMNSLLSSCVSTPRSSFYGSDIGNVVLDNKTNSIILETEAADLGNDERSKKPG
             360       370       380       390       400       410 

         490       500       510       520       530       540     
pF1KA1 TPGTPGSHDLETALRRLSLRRENYLSERRFFEEEQERKLQELAEKGELRSGSLTPTESIM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TPGTPGSHDLETALRRLSLRRENYLSERRFFEEEQERKLQELAEKGELRSGSLTPTESIM
             420       430       440       450       460       470 

         550       560       570       580       590       600     
pF1KA1 SLGTHSRFSEFTGFSGMSFSSRSYLPEKLQIVKPLEGSATLHHWQQLAQPHLGGILDPRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLGTHSRFSEFTGFSGMSFSSRSYLPEKLQIVKPLEGSATLHHWQQLAQPHLGGILDPRP
             480       490       500       510       520       530 

         610       620       630       640       650       660     
pF1KA1 GVVTKGFRTLDVDLDEVYCLNDFEEDDTGDHISLPRLATSTPVQHPETSAHHPGKCMSQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GVVTKGFRTLDVDLDEVYCLNDFEEDDTGDHISLPRLATSTPVQHPETSAHHPGKCMSQT
             540       550       560       570       580       590 

         670       680       690       700       710       720     
pF1KA1 NSTFTFTTCRILHPSDELTRVTPSLNSAPTPACGSTSHLKSTPVATPCTPRRLSLAESFT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NSTFTFTTCRILHPSDELTRVTPSLNSAPTPACGSTSHLKSTPVATPCTPRRLSLAESFT
             600       610       620       630       640       650 

         730       740       750       760       770       780     
pF1KA1 NTRESTTTMSTSLGLVWLLKERGISAAVYDPQSWDRAGRGSLLHSYTPKMAVIPSTPPNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NTRESTTTMSTSLGLVWLLKERGISAAVYDPQSWDRAGRGSLLHSYTPKMAVIPSTPPNS
             660       670       680       690       700       710 

         790       800       810       820       830       840     
pF1KA1 PMQTPTSSPPSFEFKCTSPPYDNFLASKPASSILREVREKNVRSSESQTDVSVSNLNLVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PMQTPTSSPPSFEFKCTSPPYDNFLASKPASSILREVREKNVRSSESQTDVSVSNLNLVD
             720       730       740       750       760       770 

         850       860       870       880       890       900     
pF1KA1 KVRRFGVAKVVNSGRAHVPTLTEEQGPLLCGPPGPAPALVPRGLVPEGLPLRCPTVTSAI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KVRRFGVAKVVNSGRAHVPTLTEEQGPLLCGPPGPAPALVPRGLVPEGLPLRCPTVTSAI
             780       790       800       810       820       830 

         910       920       930       940       950   
pF1KA1 GGLQLNSGIRRNRSFPTMVGSSMQMKAPVTLTSGILMGAKLSKQTSLR
       ::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GGLQLNSGIRRNRSFPTMVGSSMQMKAPVTLTSGILMGAKLSKQTSLR
             840       850       860       870         

>>XP_005265017 (OMIM: 608112) PREDICTED: trafficking kin  (712 aa)
 initn: 4460 init1: 4460 opt: 4460  Z-score: 2652.9  bits: 501.8 E(85289): 5e-141
Smith-Waterman score: 4460; 100.0% identity (100.0% similar) in 688 aa overlap (1-688:1-688)

               10        20        30        40        50        60
pF1KA1 MALVFQFGQPVRAQPLPGLCHGKLIRTNACDVCNSTDLPEVEIISLLEEQLPHYKLRADT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MALVFQFGQPVRAQPLPGLCHGKLIRTNACDVCNSTDLPEVEIISLLEEQLPHYKLRADT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA1 IYGYDHDDWLHTPLISPDANIDLTTEQIEETLKYFLLCAERVGQMTKTYNDIDAVTRLLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IYGYDHDDWLHTPLISPDANIDLTTEQIEETLKYFLLCAERVGQMTKTYNDIDAVTRLLE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA1 EKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIREEVSQLRHELSMKDELLQFYTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIREEVSQLRHELSMKDELLQFYTS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA1 AAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQKKLKDLEEENVVLRSEASQLKTETIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQKKLKDLEEENVVLRSEASQLKTETIT
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA1 YEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQQEEITHLLSQIVDLQKKAKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQQEEITHLLSQIVDLQKKAKA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA1 CAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELKNLRNKTMPNTTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELKNLRNKTMPNTTS
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA1 RRYHSLGLFPMDSLAAEIEGTMRKELQLEEAESPDITHQKRVFETVRNINQVVKQRSLTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RRYHSLGLFPMDSLAAEIEGTMRKELQLEEAESPDITHQKRVFETVRNINQVVKQRSLTP
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA1 SPMNIPGSNQSSAMNSLLSSCVSTPRSSFYGSDIGNVVLDNKTNSIILETEAADLGNDER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SPMNIPGSNQSSAMNSLLSSCVSTPRSSFYGSDIGNVVLDNKTNSIILETEAADLGNDER
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA1 SKKPGTPGTPGSHDLETALRRLSLRRENYLSERRFFEEEQERKLQELAEKGELRSGSLTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SKKPGTPGTPGSHDLETALRRLSLRRENYLSERRFFEEEQERKLQELAEKGELRSGSLTP
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA1 TESIMSLGTHSRFSEFTGFSGMSFSSRSYLPEKLQIVKPLEGSATLHHWQQLAQPHLGGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TESIMSLGTHSRFSEFTGFSGMSFSSRSYLPEKLQIVKPLEGSATLHHWQQLAQPHLGGI
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA1 LDPRPGVVTKGFRTLDVDLDEVYCLNDFEEDDTGDHISLPRLATSTPVQHPETSAHHPGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LDPRPGVVTKGFRTLDVDLDEVYCLNDFEEDDTGDHISLPRLATSTPVQHPETSAHHPGK
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA1 CMSQTNSTFTFTTCRILHPSDELTRVTPSLNSAPTPACGSTSHLKSTPVATPCTPRRLSL
       ::::::::::::::::::::::::::::                                
XP_005 CMSQTNSTFTFTTCRILHPSDELTRVTPRSCEEDDEAAICPVELRGDIGQRV        
              670       680       690       700       710          

>>XP_005265019 (OMIM: 608112) PREDICTED: trafficking kin  (666 aa)
 initn: 4220 init1: 4220 opt: 4231  Z-score: 2518.1  bits: 476.8 E(85289): 1.6e-133
Smith-Waterman score: 4231; 99.1% identity (99.4% similar) in 663 aa overlap (1-659:1-663)

               10        20        30        40        50        60
pF1KA1 MALVFQFGQPVRAQPLPGLCHGKLIRTNACDVCNSTDLPEVEIISLLEEQLPHYKLRADT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MALVFQFGQPVRAQPLPGLCHGKLIRTNACDVCNSTDLPEVEIISLLEEQLPHYKLRADT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA1 IYGYDHDDWLHTPLISPDANIDLTTEQIEETLKYFLLCAERVGQMTKTYNDIDAVTRLLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IYGYDHDDWLHTPLISPDANIDLTTEQIEETLKYFLLCAERVGQMTKTYNDIDAVTRLLE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA1 EKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIREEVSQLRHELSMKDELLQFYTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIREEVSQLRHELSMKDELLQFYTS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA1 AAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQKKLKDLEEENVVLRSEASQLKTETIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQKKLKDLEEENVVLRSEASQLKTETIT
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA1 YEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQQEEITHLLSQIVDLQKKAKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQQEEITHLLSQIVDLQKKAKA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA1 CAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELKNLRNKTMPNTTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELKNLRNKTMPNTTS
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA1 RRYHSLGLFPMDSLAAEIEGTMRKELQLEEAESPDITHQKRVFETVRNINQVVKQRSLTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RRYHSLGLFPMDSLAAEIEGTMRKELQLEEAESPDITHQKRVFETVRNINQVVKQRSLTP
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA1 SPMNIPGSNQSSAMNSLLSSCVSTPRSSFYGSDIGNVVLDNKTNSIILETEAADLGNDER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SPMNIPGSNQSSAMNSLLSSCVSTPRSSFYGSDIGNVVLDNKTNSIILETEAADLGNDER
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA1 SKKPGTPGTPGSHDLETALRRLSLRRENYLSERRFFEEEQERKLQELAEKGELRSGSLTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SKKPGTPGTPGSHDLETALRRLSLRRENYLSERRFFEEEQERKLQELAEKGELRSGSLTP
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA1 TESIMSLGTHSRFSEFTGFSGMSFSSRSYLPEKLQIVKPLEGSATLHHWQQLAQPHLGGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TESIMSLGTHSRFSEFTGFSGMSFSSRSYLPEKLQIVKPLEGSATLHHWQQLAQPHLGGI
              550       560       570       580       590       600

              610       620       630       640       650          
pF1KA1 LDPRPGVVTKGFRTLDVDLDEVYCLNDFEEDDTGDHISLPRLATSTPVQHPETSA----H
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::.    .
XP_005 LDPRPGVVTKGFRTLDVDLDEVYCLNDFEEDDTGDHISLPRLATSTPVQHPETSGREVQQ
              610       620       630       640       650       660

        660       670       680       690       700       710      
pF1KA1 HPGKCMSQTNSTFTFTTCRILHPSDELTRVTPSLNSAPTPACGSTSHLKSTPVATPCTPR
       :::                                                         
XP_005 HPGSQW                                                      
                                                                   

>>XP_006713092 (OMIM: 608112) PREDICTED: trafficking kin  (666 aa)
 initn: 4220 init1: 4220 opt: 4231  Z-score: 2518.1  bits: 476.8 E(85289): 1.6e-133
Smith-Waterman score: 4231; 99.1% identity (99.4% similar) in 663 aa overlap (1-659:1-663)

               10        20        30        40        50        60
pF1KA1 MALVFQFGQPVRAQPLPGLCHGKLIRTNACDVCNSTDLPEVEIISLLEEQLPHYKLRADT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MALVFQFGQPVRAQPLPGLCHGKLIRTNACDVCNSTDLPEVEIISLLEEQLPHYKLRADT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA1 IYGYDHDDWLHTPLISPDANIDLTTEQIEETLKYFLLCAERVGQMTKTYNDIDAVTRLLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IYGYDHDDWLHTPLISPDANIDLTTEQIEETLKYFLLCAERVGQMTKTYNDIDAVTRLLE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA1 EKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIREEVSQLRHELSMKDELLQFYTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIREEVSQLRHELSMKDELLQFYTS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA1 AAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQKKLKDLEEENVVLRSEASQLKTETIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQKKLKDLEEENVVLRSEASQLKTETIT
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA1 YEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQQEEITHLLSQIVDLQKKAKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQQEEITHLLSQIVDLQKKAKA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA1 CAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELKNLRNKTMPNTTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELKNLRNKTMPNTTS
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA1 RRYHSLGLFPMDSLAAEIEGTMRKELQLEEAESPDITHQKRVFETVRNINQVVKQRSLTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RRYHSLGLFPMDSLAAEIEGTMRKELQLEEAESPDITHQKRVFETVRNINQVVKQRSLTP
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA1 SPMNIPGSNQSSAMNSLLSSCVSTPRSSFYGSDIGNVVLDNKTNSIILETEAADLGNDER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SPMNIPGSNQSSAMNSLLSSCVSTPRSSFYGSDIGNVVLDNKTNSIILETEAADLGNDER
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA1 SKKPGTPGTPGSHDLETALRRLSLRRENYLSERRFFEEEQERKLQELAEKGELRSGSLTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SKKPGTPGTPGSHDLETALRRLSLRRENYLSERRFFEEEQERKLQELAEKGELRSGSLTP
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA1 TESIMSLGTHSRFSEFTGFSGMSFSSRSYLPEKLQIVKPLEGSATLHHWQQLAQPHLGGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TESIMSLGTHSRFSEFTGFSGMSFSSRSYLPEKLQIVKPLEGSATLHHWQQLAQPHLGGI
              550       560       570       580       590       600

              610       620       630       640       650          
pF1KA1 LDPRPGVVTKGFRTLDVDLDEVYCLNDFEEDDTGDHISLPRLATSTPVQHPETSA----H
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::.    .
XP_006 LDPRPGVVTKGFRTLDVDLDEVYCLNDFEEDDTGDHISLPRLATSTPVQHPETSGREVQQ
              610       620       630       640       650       660

        660       670       680       690       700       710      
pF1KA1 HPGKCMSQTNSTFTFTTCRILHPSDELTRVTPSLNSAPTPACGSTSHLKSTPVATPCTPR
       :::                                                         
XP_006 HPGSQW                                                      
                                                                   

>>XP_011531791 (OMIM: 608112) PREDICTED: trafficking kin  (664 aa)
 initn: 4220 init1: 4220 opt: 4226  Z-score: 2515.1  bits: 476.2 E(85289): 2.4e-133
Smith-Waterman score: 4226; 99.1% identity (99.1% similar) in 663 aa overlap (1-659:1-663)

               10        20        30        40        50        60
pF1KA1 MALVFQFGQPVRAQPLPGLCHGKLIRTNACDVCNSTDLPEVEIISLLEEQLPHYKLRADT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MALVFQFGQPVRAQPLPGLCHGKLIRTNACDVCNSTDLPEVEIISLLEEQLPHYKLRADT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA1 IYGYDHDDWLHTPLISPDANIDLTTEQIEETLKYFLLCAERVGQMTKTYNDIDAVTRLLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IYGYDHDDWLHTPLISPDANIDLTTEQIEETLKYFLLCAERVGQMTKTYNDIDAVTRLLE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA1 EKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIREEVSQLRHELSMKDELLQFYTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIREEVSQLRHELSMKDELLQFYTS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA1 AAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQKKLKDLEEENVVLRSEASQLKTETIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQKKLKDLEEENVVLRSEASQLKTETIT
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA1 YEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQQEEITHLLSQIVDLQKKAKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQQEEITHLLSQIVDLQKKAKA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA1 CAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELKNLRNKTMPNTTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELKNLRNKTMPNTTS
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA1 RRYHSLGLFPMDSLAAEIEGTMRKELQLEEAESPDITHQKRVFETVRNINQVVKQRSLTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RRYHSLGLFPMDSLAAEIEGTMRKELQLEEAESPDITHQKRVFETVRNINQVVKQRSLTP
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA1 SPMNIPGSNQSSAMNSLLSSCVSTPRSSFYGSDIGNVVLDNKTNSIILETEAADLGNDER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPMNIPGSNQSSAMNSLLSSCVSTPRSSFYGSDIGNVVLDNKTNSIILETEAADLGNDER
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA1 SKKPGTPGTPGSHDLETALRRLSLRRENYLSERRFFEEEQERKLQELAEKGELRSGSLTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKKPGTPGTPGSHDLETALRRLSLRRENYLSERRFFEEEQERKLQELAEKGELRSGSLTP
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA1 TESIMSLGTHSRFSEFTGFSGMSFSSRSYLPEKLQIVKPLEGSATLHHWQQLAQPHLGGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TESIMSLGTHSRFSEFTGFSGMSFSSRSYLPEKLQIVKPLEGSATLHHWQQLAQPHLGGI
              550       560       570       580       590       600

              610       620       630       640       650          
pF1KA1 LDPRPGVVTKGFRTLDVDLDEVYCLNDFEEDDTGDHISLPRLATSTPVQHPETSAH----
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::      
XP_011 LDPRPGVVTKGFRTLDVDLDEVYCLNDFEEDDTGDHISLPRLATSTPVQHPETSELALFL
              610       620       630       640       650       660

        660       670       680       690       700       710      
pF1KA1 HPGKCMSQTNSTFTFTTCRILHPSDELTRVTPSLNSAPTPACGSTSHLKSTPVATPCTPR
       :::                                                         
XP_011 HPGL                                                        
                                                                   

>>NP_001252537 (OMIM: 608112) trafficking kinesin-bindin  (744 aa)
 initn: 4220 init1: 4220 opt: 4220  Z-score: 2510.9  bits: 475.6 E(85289): 4.1e-133
Smith-Waterman score: 4220; 100.0% identity (100.0% similar) in 654 aa overlap (1-654:1-654)

               10        20        30        40        50        60
pF1KA1 MALVFQFGQPVRAQPLPGLCHGKLIRTNACDVCNSTDLPEVEIISLLEEQLPHYKLRADT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MALVFQFGQPVRAQPLPGLCHGKLIRTNACDVCNSTDLPEVEIISLLEEQLPHYKLRADT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA1 IYGYDHDDWLHTPLISPDANIDLTTEQIEETLKYFLLCAERVGQMTKTYNDIDAVTRLLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IYGYDHDDWLHTPLISPDANIDLTTEQIEETLKYFLLCAERVGQMTKTYNDIDAVTRLLE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA1 EKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIREEVSQLRHELSMKDELLQFYTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIREEVSQLRHELSMKDELLQFYTS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA1 AAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQKKLKDLEEENVVLRSEASQLKTETIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQKKLKDLEEENVVLRSEASQLKTETIT
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA1 YEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQQEEITHLLSQIVDLQKKAKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQQEEITHLLSQIVDLQKKAKA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA1 CAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELKNLRNKTMPNTTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELKNLRNKTMPNTTS
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA1 RRYHSLGLFPMDSLAAEIEGTMRKELQLEEAESPDITHQKRVFETVRNINQVVKQRSLTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRYHSLGLFPMDSLAAEIEGTMRKELQLEEAESPDITHQKRVFETVRNINQVVKQRSLTP
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA1 SPMNIPGSNQSSAMNSLLSSCVSTPRSSFYGSDIGNVVLDNKTNSIILETEAADLGNDER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPMNIPGSNQSSAMNSLLSSCVSTPRSSFYGSDIGNVVLDNKTNSIILETEAADLGNDER
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA1 SKKPGTPGTPGSHDLETALRRLSLRRENYLSERRFFEEEQERKLQELAEKGELRSGSLTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKKPGTPGTPGSHDLETALRRLSLRRENYLSERRFFEEEQERKLQELAEKGELRSGSLTP
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA1 TESIMSLGTHSRFSEFTGFSGMSFSSRSYLPEKLQIVKPLEGSATLHHWQQLAQPHLGGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TESIMSLGTHSRFSEFTGFSGMSFSSRSYLPEKLQIVKPLEGSATLHHWQQLAQPHLGGI
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA1 LDPRPGVVTKGFRTLDVDLDEVYCLNDFEEDDTGDHISLPRLATSTPVQHPETSAHHPGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::      
NP_001 LDPRPGVVTKGFRTLDVDLDEVYCLNDFEEDDTGDHISLPRLATSTPVQHPETSGERSQA
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA1 CMSQTNSTFTFTTCRILHPSDELTRVTPSLNSAPTPACGSTSHLKSTPVATPCTPRRLSL
                                                                   
NP_001 RVTVSGSRSYPSRPQASPEEMQEPPAATEEEEEEEEEEGSGEGTTISPVNLAPFPEAEFW
              670       680       690       700       710       720

>>XP_016861401 (OMIM: 608112) PREDICTED: trafficking kin  (758 aa)
 initn: 4220 init1: 4220 opt: 4220  Z-score: 2510.8  bits: 475.6 E(85289): 4.1e-133
Smith-Waterman score: 4358; 93.7% identity (93.7% similar) in 734 aa overlap (1-688:1-734)

               10        20        30        40        50        60
pF1KA1 MALVFQFGQPVRAQPLPGLCHGKLIRTNACDVCNSTDLPEVEIISLLEEQLPHYKLRADT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MALVFQFGQPVRAQPLPGLCHGKLIRTNACDVCNSTDLPEVEIISLLEEQLPHYKLRADT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA1 IYGYDHDDWLHTPLISPDANIDLTTEQIEETLKYFLLCAERVGQMTKTYNDIDAVTRLLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IYGYDHDDWLHTPLISPDANIDLTTEQIEETLKYFLLCAERVGQMTKTYNDIDAVTRLLE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA1 EKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIREEVSQLRHELSMKDELLQFYTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIREEVSQLRHELSMKDELLQFYTS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA1 AAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQKKLKDLEEENVVLRSEASQLKTETIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQKKLKDLEEENVVLRSEASQLKTETIT
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA1 YEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQQEEITHLLSQIVDLQKKAKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQQEEITHLLSQIVDLQKKAKA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA1 CAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELKNLRNKTMPNTTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELKNLRNKTMPNTTS
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA1 RRYHSLGLFPMDSLAAEIEGTMRKELQLEEAESPDITHQKRVFETVRNINQVVKQRSLTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRYHSLGLFPMDSLAAEIEGTMRKELQLEEAESPDITHQKRVFETVRNINQVVKQRSLTP
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA1 SPMNIPGSNQSSAMNSLLSSCVSTPRSSFYGSDIGNVVLDNKTNSIILETEAADLGNDER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPMNIPGSNQSSAMNSLLSSCVSTPRSSFYGSDIGNVVLDNKTNSIILETEAADLGNDER
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA1 SKKPGTPGTPGSHDLETALRRLSLRRENYLSERRFFEEEQERKLQELAEKGELRSGSLTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKKPGTPGTPGSHDLETALRRLSLRRENYLSERRFFEEEQERKLQELAEKGELRSGSLTP
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA1 TESIMSLGTHSRFSEFTGFSGMSFSSRSYLPEKLQIVKPLEGSATLHHWQQLAQPHLGGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TESIMSLGTHSRFSEFTGFSGMSFSSRSYLPEKLQIVKPLEGSATLHHWQQLAQPHLGGI
              550       560       570       580       590       600

              610       620       630       640       650          
pF1KA1 LDPRPGVVTKGFRTLDVDLDEVYCLNDFEEDDTGDHISLPRLATSTPVQHPETS------
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::      
XP_016 LDPRPGVVTKGFRTLDVDLDEVYCLNDFEEDDTGDHISLPRLATSTPVQHPETSGERSQA
              610       620       630       640       650       660

                                                  660       670    
pF1KA1 ----------------------------------------AHHPGKCMSQTNSTFTFTTC
                                               ::::::::::::::::::::
XP_016 RVTVSGSRSYPSRPQASPEEMQEPPAATEEEEEEEEEEGSAHHPGKCMSQTNSTFTFTTC
              670       680       690       700       710       720

          680       690       700       710       720       730    
pF1KA1 RILHPSDELTRVTPSLNSAPTPACGSTSHLKSTPVATPCTPRRLSLAESFTNTRESTTTM
       ::::::::::::::                                              
XP_016 RILHPSDELTRVTPRSCEEDDEAAICPVELRGDIGQRV                      
              730       740       750                              

>>XP_016861395 (OMIM: 608112) PREDICTED: trafficking kin  (1022 aa)
 initn: 4220 init1: 4220 opt: 4220  Z-score: 2508.9  bits: 475.7 E(85289): 5.2e-133
Smith-Waterman score: 6023; 95.3% identity (95.3% similar) in 985 aa overlap (1-939:24-1008)

                                      10        20        30       
pF1KA1                        MALVFQFGQPVRAQPLPGLCHGKLIRTNACDVCNSTD
                              :::::::::::::::::::::::::::::::::::::
XP_016 MLPATEGTGMPAPLLCLWSLCLHMALVFQFGQPVRAQPLPGLCHGKLIRTNACDVCNSTD
               10        20        30        40        50        60

        40        50        60        70        80        90       
pF1KA1 LPEVEIISLLEEQLPHYKLRADTIYGYDHDDWLHTPLISPDANIDLTTEQIEETLKYFLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPEVEIISLLEEQLPHYKLRADTIYGYDHDDWLHTPLISPDANIDLTTEQIEETLKYFLL
               70        80        90       100       110       120

       100       110       120       130       140       150       
pF1KA1 CAERVGQMTKTYNDIDAVTRLLEEKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CAERVGQMTKTYNDIDAVTRLLEEKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHI
              130       140       150       160       170       180

       160       170       180       190       200       210       
pF1KA1 REEVSQLRHELSMKDELLQFYTSAAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQKKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REEVSQLRHELSMKDELLQFYTSAAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQKKL
              190       200       210       220       230       240

       220       230       240       250       260       270       
pF1KA1 KDLEEENVVLRSEASQLKTETITYEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDLEEENVVLRSEASQLKTETITYEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDA
              250       260       270       280       290       300

       280       290       300       310       320       330       
pF1KA1 ARQQEEITHLLSQIVDLQKKAKACAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARQQEEITHLLSQIVDLQKKAKACAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECM
              310       320       330       340       350       360

       340       350       360       370       380       390       
pF1KA1 EMLHEAQEELKNLRNKTMPNTTSRRYHSLGLFPMDSLAAEIEGTMRKELQLEEAESPDIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EMLHEAQEELKNLRNKTMPNTTSRRYHSLGLFPMDSLAAEIEGTMRKELQLEEAESPDIT
              370       380       390       400       410       420

       400       410       420       430       440       450       
pF1KA1 HQKRVFETVRNINQVVKQRSLTPSPMNIPGSNQSSAMNSLLSSCVSTPRSSFYGSDIGNV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HQKRVFETVRNINQVVKQRSLTPSPMNIPGSNQSSAMNSLLSSCVSTPRSSFYGSDIGNV
              430       440       450       460       470       480

       460       470       480       490       500       510       
pF1KA1 VLDNKTNSIILETEAADLGNDERSKKPGTPGTPGSHDLETALRRLSLRRENYLSERRFFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLDNKTNSIILETEAADLGNDERSKKPGTPGTPGSHDLETALRRLSLRRENYLSERRFFE
              490       500       510       520       530       540

       520       530       540       550       560       570       
pF1KA1 EEQERKLQELAEKGELRSGSLTPTESIMSLGTHSRFSEFTGFSGMSFSSRSYLPEKLQIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEQERKLQELAEKGELRSGSLTPTESIMSLGTHSRFSEFTGFSGMSFSSRSYLPEKLQIV
              550       560       570       580       590       600

       580       590       600       610       620       630       
pF1KA1 KPLEGSATLHHWQQLAQPHLGGILDPRPGVVTKGFRTLDVDLDEVYCLNDFEEDDTGDHI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KPLEGSATLHHWQQLAQPHLGGILDPRPGVVTKGFRTLDVDLDEVYCLNDFEEDDTGDHI
              610       620       630       640       650       660

       640       650                                               
pF1KA1 SLPRLATSTPVQHPETS-------------------------------------------
       :::::::::::::::::                                           
XP_016 SLPRLATSTPVQHPETSGERSQARVTVSGSRSYPSRPQASPEEMQEPPAATEEEEEEEEE
              670       680       690       700       710       720

             660       670       680       690       700       710 
pF1KA1 ---AHHPGKCMSQTNSTFTFTTCRILHPSDELTRVTPSLNSAPTPACGSTSHLKSTPVAT
          :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGSAHHPGKCMSQTNSTFTFTTCRILHPSDELTRVTPSLNSAPTPACGSTSHLKSTPVAT
              730       740       750       760       770       780

             720       730       740       750       760       770 
pF1KA1 PCTPRRLSLAESFTNTRESTTTMSTSLGLVWLLKERGISAAVYDPQSWDRAGRGSLLHSY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PCTPRRLSLAESFTNTRESTTTMSTSLGLVWLLKERGISAAVYDPQSWDRAGRGSLLHSY
              790       800       810       820       830       840

             780       790       800       810       820       830 
pF1KA1 TPKMAVIPSTPPNSPMQTPTSSPPSFEFKCTSPPYDNFLASKPASSILREVREKNVRSSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPKMAVIPSTPPNSPMQTPTSSPPSFEFKCTSPPYDNFLASKPASSILREVREKNVRSSE
              850       860       870       880       890       900

             840       850       860       870       880       890 
pF1KA1 SQTDVSVSNLNLVDKVRRFGVAKVVNSGRAHVPTLTEEQGPLLCGPPGPAPALVPRGLVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQTDVSVSNLNLVDKVRRFGVAKVVNSGRAHVPTLTEEQGPLLCGPPGPAPALVPRGLVP
              910       920       930       940       950       960

             900       910       920       930       940       950 
pF1KA1 EGLPLRCPTVTSAIGGLQLNSGIRRNRSFPTMVGSSMQMKAPVTLTSGILMGAKLSKQTS
       ::::::::::::::::::::::::::::::::::::::::::::::::            
XP_016 EGLPLRCPTVTSAIGGLQLNSGIRRNRSFPTMVGSSMQMKAPVTLTSGILMGAKLSKQTS
              970       980       990      1000      1010      1020

         
pF1KA1 LR
         
XP_016 LR
         

>>XP_016861402 (OMIM: 608112) PREDICTED: trafficking kin  (691 aa)
 initn: 4090 init1: 4090 opt: 4090  Z-score: 2434.5  bits: 461.4 E(85289): 7.2e-129
Smith-Waterman score: 4267; 96.9% identity (96.9% similar) in 688 aa overlap (1-688:1-667)

               10        20        30        40        50        60
pF1KA1 MALVFQFGQPVRAQPLPGLCHGKLIRTNACDVCNSTDLPEVEIISLLEEQLPHYKLRADT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MALVFQFGQPVRAQPLPGLCHGKLIRTNACDVCNSTDLPEVEIISLLEEQLPHYKLRADT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA1 IYGYDHDDWLHTPLISPDANIDLTTEQIEETLKYFLLCAERVGQMTKTYNDIDAVTRLLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IYGYDHDDWLHTPLISPDANIDLTTEQIEETLKYFLLCAERVGQMTKTYNDIDAVTRLLE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA1 EKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIREEVSQLRHELSMKDELLQFYTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIREEVSQLRHELSMKDELLQFYTS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA1 AAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQKKLKDLEEENVVLRSEASQLKTETIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQKKLKDLEEENVVLRSEASQLKTETIT
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA1 YEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQQEEITHLLSQIVDLQKKAKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQQEEITHLLSQIVDLQKKAKA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA1 CAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELKNLRNKTMPNTTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELKNLRNKTMPNTTS
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA1 RRYHSLGLFPMDSLAAEIEGTMRKELQLEEAESPDITHQKRVFETVRNINQVVKQRSLTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRYHSLGLFPMDSLAAEIEGTMRKELQLEEAESPDITHQKRVFETVRNINQVVKQRSLTP
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA1 SPMNIPGSNQSSAMNSLLSSCVSTPRSSFYGSDIGNVVLDNKTNSIILETEAADLGNDER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPMNIPGSNQSSAMNSLLSSCVSTPRSSFYGSDIGNVVLDNKTNSIILETEAADLGNDER
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA1 SKKPGTPGTPGSHDLETALRRLSLRRENYLSERRFFEEEQERKLQELAEKGELRSGSLTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKKPGTPGTPGSHDLETALRRLSLRRENYLSERRFFEEEQERKLQELAEKGELRSGSLTP
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA1 TESIMSLGTHSRFSEFTGFSGMSFSSRSYLPEKLQIVKPLEGSATLHHWQQLAQPHLGGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TESIMSLGTHSRFSEFTGFSGMSFSSRSYLPEKLQIVKPLEGSATLHHWQQLAQPHLGGI
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA1 LDPRPGVVTKGFRTLDVDLDEVYCLNDFEEDDTGDHISLPRLATSTPVQHPETSAHHPGK
       :::::::::::::::::::::::::::::::::                     ::::::
XP_016 LDPRPGVVTKGFRTLDVDLDEVYCLNDFEEDDT---------------------AHHPGK
              610       620       630                              

              670       680       690       700       710       720
pF1KA1 CMSQTNSTFTFTTCRILHPSDELTRVTPSLNSAPTPACGSTSHLKSTPVATPCTPRRLSL
       ::::::::::::::::::::::::::::                                
XP_016 CMSQTNSTFTFTTCRILHPSDELTRVTPRSCEEDDEAAICPVELRGDIGQRV        
     640       650       660       670       680       690         




953 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 10:42:02 2016 done: Thu Nov  3 10:42:04 2016
 Total Scan time: 16.200 Total Display time:  0.270

Function used was FASTA [36.3.4 Apr, 2011]
Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.com