Result of FASTA (ccds) for pF1KA0987
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KA0987, 1087 aa
  1>>>pF1KA0987 1087 - 1087 aa - 1087 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.6472+/-0.000932; mu= 11.9901+/- 0.056
 mean_var=128.1364+/-24.997, 0's: 0 Z-trim(110.0): 76  B-trim: 0 in 0/51
 Lambda= 0.113302
 statistics sampled from 11193 (11269) to 11193 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.695), E-opt: 0.2 (0.346), width:  16
 Scan time:  5.240

The best scores are:                                      opt bits E(32554)
CCDS11838.1 EPB41L3 gene_id:23136|Hs108|chr18      (1087) 7097 1171.9       0
CCDS62381.1 EPB41L3 gene_id:23136|Hs108|chr18      ( 865) 2989 500.4 7.2e-141
CCDS62382.1 EPB41L3 gene_id:23136|Hs108|chr18      ( 883) 2989 500.4 7.3e-141
CCDS82237.1 EPB41L3 gene_id:23136|Hs108|chr18      ( 918) 2989 500.4 7.6e-141
CCDS82236.1 EPB41L3 gene_id:23136|Hs108|chr18      ( 756) 2297 387.2 7.2e-107
CCDS58771.1 EPB41L1 gene_id:2036|Hs108|chr20       ( 880) 2116 357.7 6.6e-98
CCDS13271.1 EPB41L1 gene_id:2036|Hs108|chr20       ( 881) 2116 357.7 6.6e-98
CCDS58770.1 EPB41L1 gene_id:2036|Hs108|chr20       ( 701) 2057 348.0 4.4e-95
CCDS13272.1 EPB41L1 gene_id:2036|Hs108|chr20       ( 779) 2051 347.0 9.4e-95
CCDS59037.1 EPB41L2 gene_id:2037|Hs108|chr6        ( 747) 1943 329.4 1.9e-89
CCDS47474.1 EPB41L2 gene_id:2037|Hs108|chr6        ( 673) 1937 328.4 3.4e-89
CCDS56450.1 EPB41L2 gene_id:2037|Hs108|chr6        ( 852) 1937 328.4 4.1e-89
CCDS5141.1 EPB41L2 gene_id:2037|Hs108|chr6         (1005) 1937 328.4 4.8e-89
CCDS53288.1 EPB41 gene_id:2035|Hs108|chr1          ( 864) 1827 310.4 1.1e-83
CCDS53289.1 EPB41 gene_id:2035|Hs108|chr1          ( 720) 1821 309.4 1.8e-83
CCDS331.1 EPB41 gene_id:2035|Hs108|chr1            ( 588) 1747 297.3 6.7e-80
CCDS332.1 EPB41 gene_id:2035|Hs108|chr1            ( 641) 1747 297.3 7.2e-80
CCDS330.1 EPB41 gene_id:2035|Hs108|chr1            ( 775) 1539 263.3 1.5e-69
CCDS2129.1 PTPN4 gene_id:5775|Hs108|chr2           ( 926) 1055 184.3 1.1e-45
CCDS9487.1 FARP1 gene_id:10160|Hs108|chr13         (1045)  949 167.0   2e-40
CCDS66572.1 FARP1 gene_id:10160|Hs108|chr13        (1076)  949 167.0 2.1e-40
CCDS54392.1 EPB41L5 gene_id:57669|Hs108|chr2       ( 505)  934 164.4   6e-40
CCDS54393.1 EPB41L5 gene_id:57669|Hs108|chr2       ( 687)  934 164.4 7.8e-40
CCDS82506.1 EPB41L5 gene_id:57669|Hs108|chr2       ( 732)  934 164.4 8.2e-40
CCDS2130.1 EPB41L5 gene_id:57669|Hs108|chr2        ( 733)  934 164.4 8.2e-40
CCDS43860.1 EPB41L4B gene_id:54566|Hs108|chr9      ( 518)  905 159.6 1.6e-38
CCDS43859.1 EPB41L4B gene_id:54566|Hs108|chr9      ( 900)  905 159.7 2.6e-38
CCDS59133.1 FRMD3 gene_id:257019|Hs108|chr9        ( 556)  888 156.9 1.2e-37
CCDS43840.1 FRMD3 gene_id:257019|Hs108|chr9        ( 597)  888 156.9 1.3e-37
CCDS63198.1 FARP2 gene_id:9855|Hs108|chr2          ( 638)  886 156.6 1.7e-37
CCDS63197.1 FARP2 gene_id:9855|Hs108|chr2          ( 647)  886 156.6 1.7e-37
CCDS33424.1 FARP2 gene_id:9855|Hs108|chr2          (1054)  886 156.7 2.6e-37
CCDS43350.1 EPB41L4A gene_id:64097|Hs108|chr5      ( 686)  876 154.9 5.5e-37
CCDS10107.2 FRMD5 gene_id:84978|Hs108|chr15        ( 570)  835 148.2 4.9e-35
CCDS35397.1 FRMD7 gene_id:90167|Hs108|chrX         ( 714)  826 146.8 1.7e-34
CCDS75852.1 FRMD3 gene_id:257019|Hs108|chr9        ( 553)  821 145.9 2.3e-34
CCDS6776.1 PTPN3 gene_id:5774|Hs108|chr9           ( 913)  768 137.3 1.5e-31
CCDS78504.1 FRMD7 gene_id:90167|Hs108|chrX         ( 699)  627 114.2   1e-24
CCDS73716.1 FRMD5 gene_id:84978|Hs108|chr15        ( 414)  565 104.0 7.2e-22
CCDS9884.1 PTPN21 gene_id:11099|Hs108|chr14        (1174)  561 103.6 2.8e-21
CCDS48001.1 PTPN3 gene_id:5774|Hs108|chr9          ( 782)  518 96.4 2.6e-19
CCDS48000.1 PTPN3 gene_id:5774|Hs108|chr9          ( 737)  507 94.6 8.5e-19
CCDS4536.1 MYLIP gene_id:29116|Hs108|chr6          ( 445)  428 81.6 4.2e-15
CCDS1514.1 PTPN14 gene_id:5784|Hs108|chr1          (1187)  435 83.0 4.5e-15
CCDS5258.1 EZR gene_id:7430|Hs108|chr6             ( 586)  355 69.7 2.1e-11
CCDS8343.1 RDX gene_id:5962|Hs108|chr11            ( 583)  344 67.9 7.3e-11
CCDS58174.1 RDX gene_id:5962|Hs108|chr11           ( 604)  344 68.0 7.5e-11


>>CCDS11838.1 EPB41L3 gene_id:23136|Hs108|chr18           (1087 aa)
 initn: 7097 init1: 7097 opt: 7097  Z-score: 6270.0  bits: 1171.9 E(32554):    0
Smith-Waterman score: 7097; 100.0% identity (100.0% similar) in 1087 aa overlap (1-1087:1-1087)

               10        20        30        40        50        60
pF1KA0 MTTESGSDSESKPDQEAEPQEAAGAQGRAGAPVPEPPKEEQQQALEQFAAAAAHSTPVRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 MTTESGSDSESKPDQEAEPQEAAGAQGRAGAPVPEPPKEEQQQALEQFAAAAAHSTPVRR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 EVTDKEQEFAARAAKQLEYQQLEDDKLSQKSSSSKLSRSPLKIVKKPKSMQCKVILLDGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 EVTDKEQEFAARAAKQLEYQQLEDDKLSQKSSSSKLSRSPLKIVKKPKSMQCKVILLDGS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 EYTCDVEKRSRGQVLFDKVCEHLNLLEKDYFGLTYRDAENQKNWLDPAKEIKKQVRSGAW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 EYTCDVEKRSRGQVLFDKVCEHLNLLEKDYFGLTYRDAENQKNWLDPAKEIKKQVRSGAW
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 HFSFNVKFYPPDPAQLSEDITRYYLCLQLRDDIVSGRLPCSFVTLALLGSYTVQSELGDY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 HFSFNVKFYPPDPAQLSEDITRYYLCLQLRDDIVSGRLPCSFVTLALLGSYTVQSELGDY
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 DPDECGSDYISEFRFAPNHTKELEDKVIELHKSHRGMTPAEAEMHFLENAKKLSMYGVDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 DPDECGSDYISEFRFAPNHTKELEDKVIELHKSHRGMTPAEAEMHFLENAKKLSMYGVDL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 HHAKDSEGVEIMLGVCASGLLIYRDRLRINRFAWPKVLKISYKRNNFYIKIRPGEFEQFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 HHAKDSEGVEIMLGVCASGLLIYRDRLRINRFAWPKVLKISYKRNNFYIKIRPGEFEQFE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 STIGFKLPNHRAAKRLWKVCVEHHTFFRLLLPEAPPKKFLTLGSKFRYSGRTQAQTRRAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 STIGFKLPNHRAAKRLWKVCVEHHTFFRLLLPEAPPKKFLTLGSKFRYSGRTQAQTRRAS
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 ALIDRPAPYFERSSSKRYTMSRSLDGEVGTGQYATTKGISQTNLITTVTPEKKAEEERDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 ALIDRPAPYFERSSSKRYTMSRSLDGEVGTGQYATTKGISQTNLITTVTPEKKAEEERDE
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 EEDKRRKGEEVTPISAIRHEGKSPGLGTDSCPLSPPSTHCAPTSPTELRRRCKENDCKLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 EEDKRRKGEEVTPISAIRHEGKSPGLGTDSCPLSPPSTHCAPTSPTELRRRCKENDCKLP
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 GYEPSRAEHLPGEPALDSDGPGRPYLGDQDVAFSYRQQTGKGTTLFSFSLQLPESFPSLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 GYEPSRAEHLPGEPALDSDGPGRPYLGDQDVAFSYRQQTGKGTTLFSFSLQLPESFPSLL
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 DDDGYLSFPNLSETNLLPQSLQHYLPIRSPSLVPCFLFIFFFLLSASFSVPYALTLSFPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 DDDGYLSFPNLSETNLLPQSLQHYLPIRSPSLVPCFLFIFFFLLSASFSVPYALTLSFPL
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 ALCLCYLEPKAASLSASLDNDPSDSSEEETDSERTDTAADGETTATESDQEEDAELKAQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 ALCLCYLEPKAASLSASLDNDPSDSSEEETDSERTDTAADGETTATESDQEEDAELKAQE
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 LEKTQDDLMKHQTNISELKRTFLETSTDTAVTNEWEKRLSTSPVRLAARQEDAPMIEPLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 LEKTQDDLMKHQTNISELKRTFLETSTDTAVTNEWEKRLSTSPVRLAARQEDAPMIEPLV
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 PEETKQSSGEKLMDGSEIFSLLESARKPTEFIGGVTSTSQSWVQKMETKTESSGIETEPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 PEETKQSSGEKLMDGSEIFSLLESARKPTEFIGGVTSTSQSWVQKMETKTESSGIETEPT
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA0 VHHLPLSTEKVVQETVLVEERRVVHASGDASYSAGDSGDAAAQPAFTGIKGKEGSALTEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 VHHLPLSTEKVVQETVLVEERRVVHASGDASYSAGDSGDAAAQPAFTGIKGKEGSALTEG
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA0 AKEEGGEEVAKAVLEQEETAAASRERQEEQSAAIHISETLEQKPHFESSTVKTETISFGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 AKEEGGEEVAKAVLEQEETAAASRERQEEQSAAIHISETLEQKPHFESSTVKTETISFGS
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KA0 VSPGGVKLEISTKEVPVVHTETKTITYESSQVDPGTDLEPGVLMSAQTITSETTSTTTTT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 VSPGGVKLEISTKEVPVVHTETKTITYESSQVDPGTDLEPGVLMSAQTITSETTSTTTTT
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KA0 HITKTVKGGISETRIEKRIVITGDADIDHDQALAQAIKEAKEQHPDMSVTKVVVHKETEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 HITKTVKGGISETRIEKRIVITGDADIDHDQALAQAIKEAKEQHPDMSVTKVVVHKETEI
             1030      1040      1050      1060      1070      1080

              
pF1KA0 TPEDGED
       :::::::
CCDS11 TPEDGED
              

>>CCDS62381.1 EPB41L3 gene_id:23136|Hs108|chr18           (865 aa)
 initn: 4943 init1: 2989 opt: 2989  Z-score: 2642.5  bits: 500.4 E(32554): 7.2e-141
Smith-Waterman score: 4916; 76.7% identity (76.7% similar) in 1105 aa overlap (1-1087:1-865)

               10        20        30        40        50        60
pF1KA0 MTTESGSDSESKPDQEAEPQEAAGAQGRAGAPVPEPPKEEQQQALEQFAAAAAHSTPVRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 MTTESGSDSESKPDQEAEPQEAAGAQGRAGAPVPEPPKEEQQQALEQFAAAAAHSTPVRR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 EVTDKEQEFAARAAKQLEYQQLEDDKLSQKSSSSKLSRSPLKIVKKPKSMQCKVILLDGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 EVTDKEQEFAARAAKQLEYQQLEDDKLSQKSSSSKLSRSPLKIVKKPKSMQCKVILLDGS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 EYTCDVEKRSRGQVLFDKVCEHLNLLEKDYFGLTYRDAENQKNWLDPAKEIKKQVRSGAW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 EYTCDVEKRSRGQVLFDKVCEHLNLLEKDYFGLTYRDAENQKNWLDPAKEIKKQVRSGAW
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 HFSFNVKFYPPDPAQLSEDITRYYLCLQLRDDIVSGRLPCSFVTLALLGSYTVQSELGDY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 HFSFNVKFYPPDPAQLSEDITRYYLCLQLRDDIVSGRLPCSFVTLALLGSYTVQSELGDY
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 DPDECGSDYISEFRFAPNHTKELEDKVIELHKSHRGMTPAEAEMHFLENAKKLSMYGVDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 DPDECGSDYISEFRFAPNHTKELEDKVIELHKSHRGMTPAEAEMHFLENAKKLSMYGVDL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 HHAKDSEGVEIMLGVCASGLLIYRDRLRINRFAWPKVLKISYKRNNFYIKIRPGEFEQFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 HHAKDSEGVEIMLGVCASGLLIYRDRLRINRFAWPKVLKISYKRNNFYIKIRPGEFEQFE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 STIGFKLPNHRAAKRLWKVCVEHHTFFRLLLPEAPPKKFLTLGSKFRYSGRTQAQTRRAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 STIGFKLPNHRAAKRLWKVCVEHHTFFRLLLPEAPPKKFLTLGSKFRYSGRTQAQTRRAS
              370       380       390       400       410       420

              430       440                         450       460  
pF1KA0 ALIDRPAPYFERSSSKRYTMSRSLDG------------------EVGTGQYATTKGISQT
       ::::::::::::::::::::::::::                  ::::::::::::::::
CCDS62 ALIDRPAPYFERSSSKRYTMSRSLDGASVNENHEIYMKDSMSAAEVGTGQYATTKGISQT
              430       440       450       460       470       480

            470       480       490       500       510       520  
pF1KA0 NLITTVTPEKKAEEERDEEEDKRRKGEEVTPISAIRHEGKSPGLGTDSCPLSPPSTHCAP
       ::::::::::::::::::::::::::::::::::::::::                    
CCDS62 NLITTVTPEKKAEEERDEEEDKRRKGEEVTPISAIRHEGK--------------------
              490       500       510       520                    

            530       540       550       560       570       580  
pF1KA0 TSPTELRRRCKENDCKLPGYEPSRAEHLPGEPALDSDGPGRPYLGDQDVAFSYRQQTGKG
                                                                   
CCDS62 ------------------------------------------------------------
                                                                   

            590       600       610       620       630       640  
pF1KA0 TTLFSFSLQLPESFPSLLDDDGYLSFPNLSETNLLPQSLQHYLPIRSPSLVPCFLFIFFF
                                                                   
CCDS62 ------------------------------------------------------------
                                                                   

            650       660       670       680       690       700  
pF1KA0 LLSASFSVPYALTLSFPLALCLCYLEPKAASLSASLDNDPSDSSEEETDSERTDTAADGE
                                                      :::::::::::::
CCDS62 -----------------------------------------------TDSERTDTAADGE
                                                             530   

            710       720       730       740       750       760  
pF1KA0 TTATESDQEEDAELKAQELEKTQDDLMKHQTNISELKRTFLETSTDTAVTNEWEKRLSTS
       :::::            :::::::::::::::::::::::::::::::::::::::::::
CCDS62 TTATE------------ELEKTQDDLMKHQTNISELKRTFLETSTDTAVTNEWEKRLSTS
                       540       550       560       570       580 

            770       780       790       800       810       820  
pF1KA0 PVRLAARQEDAPMIEPLVPEETKQSSGEKLMDGSEIFSLLESARKPTEFIGGVTSTSQSW
       :::::::::::::::::::::                                       
CCDS62 PVRLAARQEDAPMIEPLVPEE---------------------------------------
             590       600                                         

            830       840       850       860       870       880  
pF1KA0 VQKMETKTESSGIETEPTVHHLPLSTEKVVQETVLVEERRVVHASGDASYSAGDSGDAAA
         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 --KMETKTESSGIETEPTVHHLPLSTEKVVQETVLVEERRVVHASGDASYSAGDSGDAAA
              610       620       630       640       650       660

            890       900       910       920       930       940  
pF1KA0 QPAFTGIKGKEGSALTEGAKEEGGEEVAKAVLEQEETAAASRERQEEQSAAIHISETLEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 QPAFTGIKGKEGSALTEGAKEEGGEEVAKAVLEQEETAAASRERQEEQSAAIHISETLEQ
              670       680       690       700       710       720

            950       960       970       980       990      1000  
pF1KA0 KPHFESSTVKTETISFGSVSPGGVKLEISTKEVPVVHTETKTITYESSQVDPGTDLEPGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 KPHFESSTVKTETISFGSVSPGGVKLEISTKEVPVVHTETKTITYESSQVDPGTDLEPGV
              730       740       750       760       770       780

           1010      1020      1030      1040      1050      1060  
pF1KA0 LMSAQTITSETTSTTTTTHITKTVKGGISETRIEKRIVITGDADIDHDQALAQAIKEAKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 LMSAQTITSETTSTTTTTHITKTVKGGISETRIEKRIVITGDADIDHDQALAQAIKEAKE
              790       800       810       820       830       840

           1070      1080       
pF1KA0 QHPDMSVTKVVVHKETEITPEDGED
       :::::::::::::::::::::::::
CCDS62 QHPDMSVTKVVVHKETEITPEDGED
              850       860     

>>CCDS62382.1 EPB41L3 gene_id:23136|Hs108|chr18           (883 aa)
 initn: 5216 init1: 2989 opt: 2989  Z-score: 2642.4  bits: 500.4 E(32554): 7.3e-141
Smith-Waterman score: 5146; 80.8% identity (80.8% similar) in 1069 aa overlap (1-1051:1-882)

               10        20        30        40        50        60
pF1KA0 MTTESGSDSESKPDQEAEPQEAAGAQGRAGAPVPEPPKEEQQQALEQFAAAAAHSTPVRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 MTTESGSDSESKPDQEAEPQEAAGAQGRAGAPVPEPPKEEQQQALEQFAAAAAHSTPVRR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 EVTDKEQEFAARAAKQLEYQQLEDDKLSQKSSSSKLSRSPLKIVKKPKSMQCKVILLDGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 EVTDKEQEFAARAAKQLEYQQLEDDKLSQKSSSSKLSRSPLKIVKKPKSMQCKVILLDGS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 EYTCDVEKRSRGQVLFDKVCEHLNLLEKDYFGLTYRDAENQKNWLDPAKEIKKQVRSGAW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 EYTCDVEKRSRGQVLFDKVCEHLNLLEKDYFGLTYRDAENQKNWLDPAKEIKKQVRSGAW
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 HFSFNVKFYPPDPAQLSEDITRYYLCLQLRDDIVSGRLPCSFVTLALLGSYTVQSELGDY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 HFSFNVKFYPPDPAQLSEDITRYYLCLQLRDDIVSGRLPCSFVTLALLGSYTVQSELGDY
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 DPDECGSDYISEFRFAPNHTKELEDKVIELHKSHRGMTPAEAEMHFLENAKKLSMYGVDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 DPDECGSDYISEFRFAPNHTKELEDKVIELHKSHRGMTPAEAEMHFLENAKKLSMYGVDL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 HHAKDSEGVEIMLGVCASGLLIYRDRLRINRFAWPKVLKISYKRNNFYIKIRPGEFEQFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 HHAKDSEGVEIMLGVCASGLLIYRDRLRINRFAWPKVLKISYKRNNFYIKIRPGEFEQFE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 STIGFKLPNHRAAKRLWKVCVEHHTFFRLLLPEAPPKKFLTLGSKFRYSGRTQAQTRRAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 STIGFKLPNHRAAKRLWKVCVEHHTFFRLLLPEAPPKKFLTLGSKFRYSGRTQAQTRRAS
              370       380       390       400       410       420

              430       440                         450       460  
pF1KA0 ALIDRPAPYFERSSSKRYTMSRSLDG------------------EVGTGQYATTKGISQT
       ::::::::::::::::::::::::::                  ::::::::::::::::
CCDS62 ALIDRPAPYFERSSSKRYTMSRSLDGASVNENHEIYMKDSMSAAEVGTGQYATTKGISQT
              430       440       450       460       470       480

            470       480       490       500       510       520  
pF1KA0 NLITTVTPEKKAEEERDEEEDKRRKGEEVTPISAIRHEGKSPGLGTDSCPLSPPSTHCAP
       ::::::::::::::::::::::::::::::::::::::::                    
CCDS62 NLITTVTPEKKAEEERDEEEDKRRKGEEVTPISAIRHEGK--------------------
              490       500       510       520                    

            530       540       550       560       570       580  
pF1KA0 TSPTELRRRCKENDCKLPGYEPSRAEHLPGEPALDSDGPGRPYLGDQDVAFSYRQQTGKG
                                                                   
CCDS62 ------------------------------------------------------------
                                                                   

            590       600       610       620       630       640  
pF1KA0 TTLFSFSLQLPESFPSLLDDDGYLSFPNLSETNLLPQSLQHYLPIRSPSLVPCFLFIFFF
                                                                   
CCDS62 ------------------------------------------------------------
                                                                   

            650       660       670       680       690       700  
pF1KA0 LLSASFSVPYALTLSFPLALCLCYLEPKAASLSASLDNDPSDSSEEETDSERTDTAADGE
                                                      :::::::::::::
CCDS62 -----------------------------------------------TDSERTDTAADGE
                                                             530   

            710       720       730       740       750       760  
pF1KA0 TTATESDQEEDAELKAQELEKTQDDLMKHQTNISELKRTFLETSTDTAVTNEWEKRLSTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 TTATESDQEEDAELKAQELEKTQDDLMKHQTNISELKRTFLETSTDTAVTNEWEKRLSTS
           540       550       560       570       580       590   

            770       780       790       800       810       820  
pF1KA0 PVRLAARQEDAPMIEPLVPEETKQSSGEKLMDGSEIFSLLESARKPTEFIGGVTSTSQSW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 PVRLAARQEDAPMIEPLVPEETKQSSGEKLMDGSEIFSLLESARKPTEFIGGVTSTSQSW
           600       610       620       630       640       650   

            830       840       850       860       870       880  
pF1KA0 VQKMETKTESSGIETEPTVHHLPLSTEKVVQETVLVEERRVVHASGDASYSAGDSGDAAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 VQKMETKTESSGIETEPTVHHLPLSTEKVVQETVLVEERRVVHASGDASYSAGDSGDAAA
           660       670       680       690       700       710   

            890       900       910       920       930       940  
pF1KA0 QPAFTGIKGKEGSALTEGAKEEGGEEVAKAVLEQEETAAASRERQEEQSAAIHISETLEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 QPAFTGIKGKEGSALTEGAKEEGGEEVAKAVLEQEETAAASRERQEEQSAAIHISETLEQ
           720       730       740       750       760       770   

            950       960       970       980       990      1000  
pF1KA0 KPHFESSTVKTETISFGSVSPGGVKLEISTKEVPVVHTETKTITYESSQVDPGTDLEPGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 KPHFESSTVKTETISFGSVSPGGVKLEISTKEVPVVHTETKTITYESSQVDPGTDLEPGV
           780       790       800       810       820       830   

           1010      1020      1030      1040      1050      1060  
pF1KA0 LMSAQTITSETTSTTTTTHITKTVKGGISETRIEKRIVITGDADIDHDQALAQAIKEAKE
       :::::::::::::::::::::::::::::::::::::::::::::::::           
CCDS62 LMSAQTITSETTSTTTTTHITKTVKGGISETRIEKRIVITGDADIDHDQE          
           840       850       860       870       880             

           1070      1080       
pF1KA0 QHPDMSVTKVVVHKETEITPEDGED

>>CCDS82237.1 EPB41L3 gene_id:23136|Hs108|chr18           (918 aa)
 initn: 5444 init1: 2989 opt: 2989  Z-score: 2642.1  bits: 500.4 E(32554): 7.6e-141
Smith-Waterman score: 5374; 81.4% identity (81.4% similar) in 1105 aa overlap (1-1087:1-918)

               10        20        30        40        50        60
pF1KA0 MTTESGSDSESKPDQEAEPQEAAGAQGRAGAPVPEPPKEEQQQALEQFAAAAAHSTPVRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 MTTESGSDSESKPDQEAEPQEAAGAQGRAGAPVPEPPKEEQQQALEQFAAAAAHSTPVRR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 EVTDKEQEFAARAAKQLEYQQLEDDKLSQKSSSSKLSRSPLKIVKKPKSMQCKVILLDGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 EVTDKEQEFAARAAKQLEYQQLEDDKLSQKSSSSKLSRSPLKIVKKPKSMQCKVILLDGS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 EYTCDVEKRSRGQVLFDKVCEHLNLLEKDYFGLTYRDAENQKNWLDPAKEIKKQVRSGAW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 EYTCDVEKRSRGQVLFDKVCEHLNLLEKDYFGLTYRDAENQKNWLDPAKEIKKQVRSGAW
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 HFSFNVKFYPPDPAQLSEDITRYYLCLQLRDDIVSGRLPCSFVTLALLGSYTVQSELGDY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 HFSFNVKFYPPDPAQLSEDITRYYLCLQLRDDIVSGRLPCSFVTLALLGSYTVQSELGDY
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 DPDECGSDYISEFRFAPNHTKELEDKVIELHKSHRGMTPAEAEMHFLENAKKLSMYGVDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 DPDECGSDYISEFRFAPNHTKELEDKVIELHKSHRGMTPAEAEMHFLENAKKLSMYGVDL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 HHAKDSEGVEIMLGVCASGLLIYRDRLRINRFAWPKVLKISYKRNNFYIKIRPGEFEQFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 HHAKDSEGVEIMLGVCASGLLIYRDRLRINRFAWPKVLKISYKRNNFYIKIRPGEFEQFE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 STIGFKLPNHRAAKRLWKVCVEHHTFFRLLLPEAPPKKFLTLGSKFRYSGRTQAQTRRAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 STIGFKLPNHRAAKRLWKVCVEHHTFFRLLLPEAPPKKFLTLGSKFRYSGRTQAQTRRAS
              370       380       390       400       410       420

              430       440                         450       460  
pF1KA0 ALIDRPAPYFERSSSKRYTMSRSLDG------------------EVGTGQYATTKGISQT
       ::::::::::::::::::::::::::                  ::::::::::::::::
CCDS82 ALIDRPAPYFERSSSKRYTMSRSLDGASVNENHEIYMKDSMSAAEVGTGQYATTKGISQT
              430       440       450       460       470       480

            470       480       490       500       510       520  
pF1KA0 NLITTVTPEKKAEEERDEEEDKRRKGEEVTPISAIRHEGKSPGLGTDSCPLSPPSTHCAP
       ::::::::::::::::::::::::::::::::::::::::                    
CCDS82 NLITTVTPEKKAEEERDEEEDKRRKGEEVTPISAIRHEGK--------------------
              490       500       510       520                    

            530       540       550       560       570       580  
pF1KA0 TSPTELRRRCKENDCKLPGYEPSRAEHLPGEPALDSDGPGRPYLGDQDVAFSYRQQTGKG
                                                                   
CCDS82 ------------------------------------------------------------
                                                                   

            590       600       610       620       630       640  
pF1KA0 TTLFSFSLQLPESFPSLLDDDGYLSFPNLSETNLLPQSLQHYLPIRSPSLVPCFLFIFFF
                                                                   
CCDS82 ------------------------------------------------------------
                                                                   

            650       660       670       680       690       700  
pF1KA0 LLSASFSVPYALTLSFPLALCLCYLEPKAASLSASLDNDPSDSSEEETDSERTDTAADGE
                                                      :::::::::::::
CCDS82 -----------------------------------------------TDSERTDTAADGE
                                                             530   

            710       720       730       740       750       760  
pF1KA0 TTATESDQEEDAELKAQELEKTQDDLMKHQTNISELKRTFLETSTDTAVTNEWEKRLSTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 TTATESDQEEDAELKAQELEKTQDDLMKHQTNISELKRTFLETSTDTAVTNEWEKRLSTS
           540       550       560       570       580       590   

            770       780       790       800       810       820  
pF1KA0 PVRLAARQEDAPMIEPLVPEETKQSSGEKLMDGSEIFSLLESARKPTEFIGGVTSTSQSW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 PVRLAARQEDAPMIEPLVPEETKQSSGEKLMDGSEIFSLLESARKPTEFIGGVTSTSQSW
           600       610       620       630       640       650   

            830       840       850       860       870       880  
pF1KA0 VQKMETKTESSGIETEPTVHHLPLSTEKVVQETVLVEERRVVHASGDASYSAGDSGDAAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 VQKMETKTESSGIETEPTVHHLPLSTEKVVQETVLVEERRVVHASGDASYSAGDSGDAAA
           660       670       680       690       700       710   

            890       900       910       920       930       940  
pF1KA0 QPAFTGIKGKEGSALTEGAKEEGGEEVAKAVLEQEETAAASRERQEEQSAAIHISETLEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 QPAFTGIKGKEGSALTEGAKEEGGEEVAKAVLEQEETAAASRERQEEQSAAIHISETLEQ
           720       730       740       750       760       770   

            950       960       970       980       990      1000  
pF1KA0 KPHFESSTVKTETISFGSVSPGGVKLEISTKEVPVVHTETKTITYESSQVDPGTDLEPGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 KPHFESSTVKTETISFGSVSPGGVKLEISTKEVPVVHTETKTITYESSQVDPGTDLEPGV
           780       790       800       810       820       830   

           1010      1020      1030      1040      1050      1060  
pF1KA0 LMSAQTITSETTSTTTTTHITKTVKGGISETRIEKRIVITGDADIDHDQALAQAIKEAKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 LMSAQTITSETTSTTTTTHITKTVKGGISETRIEKRIVITGDADIDHDQALAQAIKEAKE
           840       850       860       870       880       890   

           1070      1080       
pF1KA0 QHPDMSVTKVVVHKETEITPEDGED
       :::::::::::::::::::::::::
CCDS82 QHPDMSVTKVVVHKETEITPEDGED
           900       910        

>>CCDS82236.1 EPB41L3 gene_id:23136|Hs108|chr18           (756 aa)
 initn: 4251 init1: 2297 opt: 2297  Z-score: 2032.1  bits: 387.2 E(32554): 7.2e-107
Smith-Waterman score: 4224; 74.1% identity (74.1% similar) in 996 aa overlap (110-1087:1-756)

      80        90       100       110       120       130         
pF1KA0 QQLEDDKLSQKSSSSKLSRSPLKIVKKPKSMQCKVILLDGSEYTCDVEKRSRGQVLFDKV
                                     ::::::::::::::::::::::::::::::
CCDS82                               MQCKVILLDGSEYTCDVEKRSRGQVLFDKV
                                             10        20        30

     140       150       160       170       180       190         
pF1KA0 CEHLNLLEKDYFGLTYRDAENQKNWLDPAKEIKKQVRSGAWHFSFNVKFYPPDPAQLSED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 CEHLNLLEKDYFGLTYRDAENQKNWLDPAKEIKKQVRSGAWHFSFNVKFYPPDPAQLSED
               40        50        60        70        80        90

     200       210       220       230       240       250         
pF1KA0 ITRYYLCLQLRDDIVSGRLPCSFVTLALLGSYTVQSELGDYDPDECGSDYISEFRFAPNH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 ITRYYLCLQLRDDIVSGRLPCSFVTLALLGSYTVQSELGDYDPDECGSDYISEFRFAPNH
              100       110       120       130       140       150

     260       270       280       290       300       310         
pF1KA0 TKELEDKVIELHKSHRGMTPAEAEMHFLENAKKLSMYGVDLHHAKDSEGVEIMLGVCASG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 TKELEDKVIELHKSHRGMTPAEAEMHFLENAKKLSMYGVDLHHAKDSEGVEIMLGVCASG
              160       170       180       190       200       210

     320       330       340       350       360       370         
pF1KA0 LLIYRDRLRINRFAWPKVLKISYKRNNFYIKIRPGEFEQFESTIGFKLPNHRAAKRLWKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 LLIYRDRLRINRFAWPKVLKISYKRNNFYIKIRPGEFEQFESTIGFKLPNHRAAKRLWKV
              220       230       240       250       260       270

     380       390       400       410       420       430         
pF1KA0 CVEHHTFFRLLLPEAPPKKFLTLGSKFRYSGRTQAQTRRASALIDRPAPYFERSSSKRYT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 CVEHHTFFRLLLPEAPPKKFLTLGSKFRYSGRTQAQTRRASALIDRPAPYFERSSSKRYT
              280       290       300       310       320       330

     440                         450       460       470       480 
pF1KA0 MSRSLDG------------------EVGTGQYATTKGISQTNLITTVTPEKKAEEERDEE
       :::::::                  :::::::::::::::::::::::::::::::::::
CCDS82 MSRSLDGASVNENHEIYMKDSMSAAEVGTGQYATTKGISQTNLITTVTPEKKAEEERDEE
              340       350       360       370       380       390

             490       500       510       520       530       540 
pF1KA0 EDKRRKGEEVTPISAIRHEGKSPGLGTDSCPLSPPSTHCAPTSPTELRRRCKENDCKLPG
       :::::::::::::::::::::                                       
CCDS82 EDKRRKGEEVTPISAIRHEGK---------------------------------------
              400       410                                        

             550       560       570       580       590       600 
pF1KA0 YEPSRAEHLPGEPALDSDGPGRPYLGDQDVAFSYRQQTGKGTTLFSFSLQLPESFPSLLD
                                                                   
CCDS82 ------------------------------------------------------------
                                                                   

             610       620       630       640       650       660 
pF1KA0 DDGYLSFPNLSETNLLPQSLQHYLPIRSPSLVPCFLFIFFFLLSASFSVPYALTLSFPLA
                                                                   
CCDS82 ------------------------------------------------------------
                                                                   

             670       680       690       700       710       720 
pF1KA0 LCLCYLEPKAASLSASLDNDPSDSSEEETDSERTDTAADGETTATESDQEEDAELKAQEL
                                   ::::::::::::::::::            ::
CCDS82 ----------------------------TDSERTDTAADGETTATE------------EL
                                         420                   430 

             730       740       750       760       770       780 
pF1KA0 EKTQDDLMKHQTNISELKRTFLETSTDTAVTNEWEKRLSTSPVRLAARQEDAPMIEPLVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 EKTQDDLMKHQTNISELKRTFLETSTDTAVTNEWEKRLSTSPVRLAARQEDAPMIEPLVP
             440       450       460       470       480       490 

             790       800       810       820       830       840 
pF1KA0 EETKQSSGEKLMDGSEIFSLLESARKPTEFIGGVTSTSQSWVQKMETKTESSGIETEPTV
       ::                                         :::::::::::::::::
CCDS82 EE-----------------------------------------KMETKTESSGIETEPTV
                                                      500       510

             850       860       870       880       890       900 
pF1KA0 HHLPLSTEKVVQETVLVEERRVVHASGDASYSAGDSGDAAAQPAFTGIKGKEGSALTEGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 HHLPLSTEKVVQETVLVEERRVVHASGDASYSAGDSGDAAAQPAFTGIKGKEGSALTEGA
              520       530       540       550       560       570

             910       920       930       940       950       960 
pF1KA0 KEEGGEEVAKAVLEQEETAAASRERQEEQSAAIHISETLEQKPHFESSTVKTETISFGSV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 KEEGGEEVAKAVLEQEETAAASRERQEEQSAAIHISETLEQKPHFESSTVKTETISFGSV
              580       590       600       610       620       630

             970       980       990      1000      1010      1020 
pF1KA0 SPGGVKLEISTKEVPVVHTETKTITYESSQVDPGTDLEPGVLMSAQTITSETTSTTTTTH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 SPGGVKLEISTKEVPVVHTETKTITYESSQVDPGTDLEPGVLMSAQTITSETTSTTTTTH
              640       650       660       670       680       690

            1030      1040      1050      1060      1070      1080 
pF1KA0 ITKTVKGGISETRIEKRIVITGDADIDHDQALAQAIKEAKEQHPDMSVTKVVVHKETEIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 ITKTVKGGISETRIEKRIVITGDADIDHDQALAQAIKEAKEQHPDMSVTKVVVHKETEIT
              700       710       720       730       740       750

             
pF1KA0 PEDGED
       ::::::
CCDS82 PEDGED
             

>>CCDS58771.1 EPB41L1 gene_id:2036|Hs108|chr20            (880 aa)
 initn: 2640 init1: 2037 opt: 2116  Z-score: 1871.2  bits: 357.7 E(32554): 6.6e-98
Smith-Waterman score: 2286; 43.5% identity (63.0% similar) in 1086 aa overlap (1-1084:1-872)

               10        20        30        40        50        60
pF1KA0 MTTESGSDSESKPDQEAEPQEAAGAQGRAGAPVPEPPKEEQQQALEQFAAAAAHSTPVRR
       ::::.: ::: :  ::  ::     : .:.: :  :     .   :   : . .. : ..
CCDS58 MTTETGPDSEVKKAQEEAPQ-----QPEAAAAVTTPVTPAGHGHPE---ANSNEKHPSQQ
               10        20             30        40           50  

               70        80        90       100       110       120
pF1KA0 EVTDKEQEFAARAAKQLEYQQLEDDKLSQKSSSSKLSRSPLKIVKKPKSMQCKVILLDGS
       ..   :: .     .. .:.  : : ::.... :: ..:: ::.:: ::  :.: :::.:
CCDS58 DTRPAEQSLDM---EEKDYS--EADGLSERTTPSKAQKSPQKIAKKYKSAICRVTLLDAS
             60             70        80        90       100       

              130       140       150       160       170       180
pF1KA0 EYTCDVEKRSRGQVLFDKVCEHLNLLEKDYFGLTYRDAENQKNWLDPAKEIKKQVRSGAW
       :: :.:::..::::::: ::::::::::::::::. ::..:::::::.::::::.::. :
CCDS58 EYECEVEKHGRGQVLFDLVCEHLNLLEKDYFGLTFCDADSQKNWLDPSKEIKKQIRSSPW
       110       120       130       140       150       160       

              190       200       210       220       230       240
pF1KA0 HFSFNVKFYPPDPAQLSEDITRYYLCLQLRDDIVSGRLPCSFVTLALLGSYTVQSELGDY
       .:.:.:::::::::::.::::::::::::: ::..::::::::: ::::::.::.:::::
CCDS58 NFAFTVKFYPPDPAQLTEDITRYYLCLQLRADIITGRLPCSFVTHALLGSYAVQAELGDY
       170       180       190       200       210       220       

              250       260       270       280       290       300
pF1KA0 DPDECGSDYISEFRFAPNHTKELEDKVIELHKSHRGMTPAEAEMHFLENAKKLSMYGVDL
       : .:  ..:.::.:::::.:.:::....::::..:::::.:::.::::::::::::::::
CCDS58 DAEEHVGNYVSELRFAPNQTRELEERIMELHKTYRGMTPGEAEIHFLENAKKLSMYGVDL
       230       240       250       260       270       280       

              310       320       330       340       350       360
pF1KA0 HHAKDSEGVEIMLGVCASGLLIYRDRLRINRFAWPKVLKISYKRNNFYIKIRPGEFEQFE
       ::::::::..:::::::.::::::::::::::::::.:::::::.::::::::::.::::
CCDS58 HHAKDSEGIDIMLGVCANGLLIYRDRLRINRFAWPKILKISYKRSNFYIKIRPGEYEQFE
       290       300       310       320       330       340       

              370       380       390       400       410       420
pF1KA0 STIGFKLPNHRAAKRLWKVCVEHHTFFRLLLPEAPPKKFLTLGSKFRYSGRTQAQTRRAS
       :::::::::::.::::::::.::::::::. :: ::: ::..:::::::::::::::.::
CCDS58 STIGFKLPNHRSAKRLWKVCIEHHTFFRLVSPEPPPKGFLVMGSKFRYSGRTQAQTRQAS
       350       360       370       380       390       400       

              430       440       450       460       470       480
pF1KA0 ALIDRPAPYFERSSSKRYTMSRSLDGEVGTGQYATTKGISQTNLITTVTPEKKAEEERDE
       ::::::::.:::::::::::::::::    ....   ..:...    . :.   ..:  :
CCDS58 ALIDRPAPFFERSSSKRYTMSRSLDG----AEFSRPASVSENH---DAGPDGDKRDEDGE
       410       420       430           440          450       460

              490       500       510       520       530       540
pF1KA0 EEDKRRKGEEVTPISAIRHEGKSPGLGTDSCPLSPPSTHCAPTSPTELRRRCKENDCKLP
          .: ..::         : ..:   :    :.: .     :.:     : :.      
CCDS58 SGGQRSEAEE--------GEVRTP---TKIKELKPEQE----TTP-----RHKQ------
              470                  480           490               

              550       560       570       580       590       600
pF1KA0 GYEPSRAEHLPGEPALDSDGPGRPYLGDQDVAFSYRQQTGKGTTLFSFSLQLPESFPSLL
              : :        : :       .:: .... . ..    .. .:. :.:  .:.
CCDS58 -------EFL--------DKP-------EDVLLKHQASINE----LKRTLKEPNS--KLI
                         500              510           520        

              610       620       630       640       650       660
pF1KA0 DDDGYLSFPNLSETNLLPQSLQHYLPIRSPSLVPCFLFIFFFLLSASFSVPYALTLSFPL
         :      .  .   ::.:     :  :::                   : .       
CCDS58 HRDR-----DWERERRLPSS-----PA-SPS-------------------PKGT------
        530            540                                550      

              670       680       690       700       710       720
pF1KA0 ALCLCYLEPKAASLSASLDNDPSDSSEEETDSERTDTAADGETTATESDQEEDAELKAQE
               :. :.  :.:     ..:::..   :   : ...:   ..:::.:. .    
CCDS58 --------PEKANERAGL----REGSEEKVKPPRP-RAPESDTGDEDQDQERDTVF----
                      560           570        580       590       

              730       740       750       760       770       780
pF1KA0 LEKTQDDLMKHQTNISELKRTFLETSTDTAVTNEWEKRLSTSPVRLAARQEDAPMIEPLV
       :. ..  . .. ..:.  . . ::. .: .: ....          ..  ::     : .
CCDS58 LKDNHLAIERKCSSITVSSTSSLEAEVDFTVIGDYH----------GSAFEDFSRSLPEL
           600       610       620                 630       640   

              790       800       810       820       830       840
pF1KA0 PEETKQSSGEKLMDGSEIFSLLESARKPTEFIGGVTSTSQSWVQKMETKTESSGIETEPT
        .. ..:. : :.     ::         ..  :. : ..          ::.:::  : 
CCDS58 DRDKSDSDTEGLL-----FS--------RDLNKGAPSQDD----------ESGGIEDSP-
           650                    660       670                    

              850       860       870       880       890       900
pF1KA0 VHHLPLSTEKVVQETVLVEERRVVHASGDASYSAGDSGDAAAQPAFTGIKGKEGSALTEG
                          .:           .: .. :   .: :  .: .  .. . .
CCDS58 -------------------DR-----------GACSTPD---MPQFEPVKTETMTVSSLA
                        680                     690       700      

              910       920       930       940       950       960
pF1KA0 AKEEGGEEVAKAVLEQEETAAASRERQEEQSAAIHISETLEQKPHFESSTVKTETISFGS
        ...   :   :::. .  ..:  . : . ::..   : .   :     .. :::::  .
CCDS58 IRKKIEPE---AVLQTR--VSAMDNTQVDGSASVG-REFIATTP-----SITTETIS--T
        710          720         730        740            750     

              970       980       990        1000      1010        
pF1KA0 VSPGGVKLEISTKEVPVVHTETKTITYESSQVDP--GTDLEPGVLMSAQTITSETTSTTT
       .  ...:   : : . ..    .:.. :  ...:  : :    :: :.   :.:: ::.:
CCDS58 TMENSLK---SGKGAAAMIPGPQTVATEIRSLSPIIGKD----VLTSTYGATAETLSTST
           760          770       780           790       800      

     1020      1030      1040      1050      1060      1070        
pF1KA0 TTHITKTVKGGISETRIEKRIVITGDADIDHDQALAQAIKEAKEQHPDMSVTKVVVHKET
       :::.:::::::.:::::::::.:::: :.:.::::: :::::: ::::: :::.::..::
CCDS58 TTHVTKTVKGGFSETRIEKRIIITGDEDVDQDQALALAIKEAKLQHPDMLVTKAVVYRET
        810       820       830       840       850       860      

     1080            
pF1KA0 EITPEDGED     
       . .::.        
CCDS58 DPSPEERDKKPQES
        870       880

>>CCDS13271.1 EPB41L1 gene_id:2036|Hs108|chr20            (881 aa)
 initn: 2630 init1: 2037 opt: 2116  Z-score: 1871.2  bits: 357.7 E(32554): 6.6e-98
Smith-Waterman score: 2296; 43.6% identity (63.1% similar) in 1086 aa overlap (1-1084:1-873)

               10        20        30        40        50        60
pF1KA0 MTTESGSDSESKPDQEAEPQEAAGAQGRAGAPVPEPPKEEQQQALEQFAAAAAHSTPVRR
       ::::.: ::: :  ::  ::     : .:.: :  :     .   :   : . .. : ..
CCDS13 MTTETGPDSEVKKAQEEAPQ-----QPEAAAAVTTPVTPAGHGHPE---ANSNEKHPSQQ
               10        20             30        40           50  

               70        80        90       100       110       120
pF1KA0 EVTDKEQEFAARAAKQLEYQQLEDDKLSQKSSSSKLSRSPLKIVKKPKSMQCKVILLDGS
       ..   :: .     .. .:.  : : ::.... :: ..:: ::.:: ::  :.: :::.:
CCDS13 DTRPAEQSLDM---EEKDYS--EADGLSERTTPSKAQKSPQKIAKKYKSAICRVTLLDAS
             60             70        80        90       100       

              130       140       150       160       170       180
pF1KA0 EYTCDVEKRSRGQVLFDKVCEHLNLLEKDYFGLTYRDAENQKNWLDPAKEIKKQVRSGAW
       :: :.:::..::::::: ::::::::::::::::. ::..:::::::.::::::.::. :
CCDS13 EYECEVEKHGRGQVLFDLVCEHLNLLEKDYFGLTFCDADSQKNWLDPSKEIKKQIRSSPW
       110       120       130       140       150       160       

              190       200       210       220       230       240
pF1KA0 HFSFNVKFYPPDPAQLSEDITRYYLCLQLRDDIVSGRLPCSFVTLALLGSYTVQSELGDY
       .:.:.:::::::::::.::::::::::::: ::..::::::::: ::::::.::.:::::
CCDS13 NFAFTVKFYPPDPAQLTEDITRYYLCLQLRADIITGRLPCSFVTHALLGSYAVQAELGDY
       170       180       190       200       210       220       

              250       260       270       280       290       300
pF1KA0 DPDECGSDYISEFRFAPNHTKELEDKVIELHKSHRGMTPAEAEMHFLENAKKLSMYGVDL
       : .:  ..:.::.:::::.:.:::....::::..:::::.:::.::::::::::::::::
CCDS13 DAEEHVGNYVSELRFAPNQTRELEERIMELHKTYRGMTPGEAEIHFLENAKKLSMYGVDL
       230       240       250       260       270       280       

              310       320       330       340       350       360
pF1KA0 HHAKDSEGVEIMLGVCASGLLIYRDRLRINRFAWPKVLKISYKRNNFYIKIRPGEFEQFE
       ::::::::..:::::::.::::::::::::::::::.:::::::.::::::::::.::::
CCDS13 HHAKDSEGIDIMLGVCANGLLIYRDRLRINRFAWPKILKISYKRSNFYIKIRPGEYEQFE
       290       300       310       320       330       340       

              370       380       390       400       410       420
pF1KA0 STIGFKLPNHRAAKRLWKVCVEHHTFFRLLLPEAPPKKFLTLGSKFRYSGRTQAQTRRAS
       :::::::::::.::::::::.::::::::. :: ::: ::..:::::::::::::::.::
CCDS13 STIGFKLPNHRSAKRLWKVCIEHHTFFRLVSPEPPPKGFLVMGSKFRYSGRTQAQTRQAS
       350       360       370       380       390       400       

              430       440       450       460       470       480
pF1KA0 ALIDRPAPYFERSSSKRYTMSRSLDGEVGTGQYATTKGISQTNLITTVTPEKKAEEERDE
       ::::::::.:::::::::::::::::    ....   ..:...    . :.   ..:  :
CCDS13 ALIDRPAPFFERSSSKRYTMSRSLDG----AEFSRPASVSENH---DAGPDGDKRDEDGE
       410       420       430           440          450       460

              490       500       510       520       530       540
pF1KA0 EEDKRRKGEEVTPISAIRHEGKSPGLGTDSCPLSPPSTHCAPTSPTELRRRCKENDCKLP
          .: ..::         : ..:   :    :.: .     :.:     : :.      
CCDS13 SGGQRSEAEE--------GEVRTP---TKIKELKPEQE----TTP-----RHKQ------
              470                  480           490               

              550       560       570       580       590       600
pF1KA0 GYEPSRAEHLPGEPALDSDGPGRPYLGDQDVAFSYRQQTGKGTTLFSFSLQLPESFPSLL
              : :        : :       .:: .... . ..    .. .:. :.:  .:.
CCDS13 -------EFL--------DKP-------EDVLLKHQASINE----LKRTLKEPNS--KLI
                         500              510           520        

              610       620       630       640       650       660
pF1KA0 DDDGYLSFPNLSETNLLPQSLQHYLPIRSPSLVPCFLFIFFFLLSASFSVPYALTLSFPL
         :      .  .   ::.:     :  :::                   : .       
CCDS13 HRDR-----DWERERRLPSS-----PA-SPS-------------------PKGT------
        530            540                                550      

              670       680       690       700       710       720
pF1KA0 ALCLCYLEPKAASLSASLDNDPSDSSEEETDSERTDTAADGETTATESDQEEDAELKAQE
               :. :.  :.:     ..:::..   :   : ...:   ..:::.:. .    
CCDS13 --------PEKANERAGL----REGSEEKVKPPRP-RAPESDTGDEDQDQERDTVF----
                      560           570        580       590       

              730       740       750       760       770       780
pF1KA0 LEKTQDDLMKHQTNISELKRTFLETSTDTAVTNEWEKRLSTSPVRLAARQEDAPMIEPLV
       :. ..  . .. ..:.  . . ::. .: .: ....          ..  ::     : .
CCDS13 LKDNHLAIERKCSSITVSSTSSLEAEVDFTVIGDYH----------GSAFEDFSRSLPEL
           600       610       620                 630       640   

              790       800       810       820       830       840
pF1KA0 PEETKQSSGEKLMDGSEIFSLLESARKPTEFIGGVTSTSQSWVQKMETKTESSGIETEPT
        .. ..:. : :.     ::         ..  :. : ..          ::.:::  : 
CCDS13 DRDKSDSDTEGLL-----FS--------RDLNKGAPSQDD----------ESGGIEDSP-
           650                    660       670                    

              850       860       870       880       890       900
pF1KA0 VHHLPLSTEKVVQETVLVEERRVVHASGDASYSAGDSGDAAAQPAFTGIKGKEGSALTEG
                          .:           .: .. :   .: :  .: .  .. . .
CCDS13 -------------------DR-----------GACSTPD---MPQFEPVKTETMTVSSLA
                        680                     690       700      

              910       920       930       940       950       960
pF1KA0 AKEEGGEEVAKAVLEQEETAAASRERQEEQSAAIHISETLEQKPHFESSTVKTETISFGS
        ...   :   ::: : ...: .  .: . ::..   : .   :     .. :::::  .
CCDS13 IRKKIEPE---AVL-QTRVSAMDNTQQVDGSASVG-REFIATTP-----SITTETIS--T
        710           720       730        740            750      

              970       980       990        1000      1010        
pF1KA0 VSPGGVKLEISTKEVPVVHTETKTITYESSQVDP--GTDLEPGVLMSAQTITSETTSTTT
       .  ...:   : : . ..    .:.. :  ...:  : :    :: :.   :.:: ::.:
CCDS13 TMENSLK---SGKGAAAMIPGPQTVATEIRSLSPIIGKD----VLTSTYGATAETLSTST
          760          770       780       790           800       

     1020      1030      1040      1050      1060      1070        
pF1KA0 TTHITKTVKGGISETRIEKRIVITGDADIDHDQALAQAIKEAKEQHPDMSVTKVVVHKET
       :::.:::::::.:::::::::.:::: :.:.::::: :::::: ::::: :::.::..::
CCDS13 TTHVTKTVKGGFSETRIEKRIIITGDEDVDQDQALALAIKEAKLQHPDMLVTKAVVYRET
       810       820       830       840       850       860       

     1080            
pF1KA0 EITPEDGED     
       . .::.        
CCDS13 DPSPEERDKKPQES
       870       880 

>>CCDS58770.1 EPB41L1 gene_id:2036|Hs108|chr20            (701 aa)
 initn: 2519 init1: 2037 opt: 2057  Z-score: 1820.6  bits: 348.0 E(32554): 4.4e-95
Smith-Waterman score: 2095; 63.8% identity (82.2% similar) in 506 aa overlap (72-571:25-515)

              50        60        70        80           90        
pF1KA0 QQALEQFAAAAAHSTPVRREVTDKEQEFAARAAKQLEYQQL---EDDKLSQKSSSSKLSR
                                     :..:.:....    : : ::.... :: ..
CCDS58       MVFLGRINEVEPAKGLAESLAPTERSVKSLDMEEKDYSEADGLSERTTPSKAQK
                     10        20        30        40        50    

      100       110       120       130       140       150        
pF1KA0 SPLKIVKKPKSMQCKVILLDGSEYTCDVEKRSRGQVLFDKVCEHLNLLEKDYFGLTYRDA
       :: ::.:: ::  :.: :::.::: :.:::..::::::: ::::::::::::::::. ::
CCDS58 SPQKIAKKYKSAICRVTLLDASEYECEVEKHGRGQVLFDLVCEHLNLLEKDYFGLTFCDA
           60        70        80        90       100       110    

      160       170       180       190       200       210        
pF1KA0 ENQKNWLDPAKEIKKQVRSGAWHFSFNVKFYPPDPAQLSEDITRYYLCLQLRDDIVSGRL
       ..:::::::.::::::.::. :.:.:.:::::::::::.::::::::::::: ::..:::
CCDS58 DSQKNWLDPSKEIKKQIRSSPWNFAFTVKFYPPDPAQLTEDITRYYLCLQLRADIITGRL
          120       130       140       150       160       170    

      220       230       240       250       260       270        
pF1KA0 PCSFVTLALLGSYTVQSELGDYDPDECGSDYISEFRFAPNHTKELEDKVIELHKSHRGMT
       :::::: ::::::.::.:::::: .:  ..:.::.:::::.:.:::....::::..::::
CCDS58 PCSFVTHALLGSYAVQAELGDYDAEEHVGNYVSELRFAPNQTRELEERIMELHKTYRGMT
          180       190       200       210       220       230    

      280       290       300       310       320       330        
pF1KA0 PAEAEMHFLENAKKLSMYGVDLHHAKDSEGVEIMLGVCASGLLIYRDRLRINRFAWPKVL
       :.:::.::::::::::::::::::::::::..:::::::.::::::::::::::::::.:
CCDS58 PGEAEIHFLENAKKLSMYGVDLHHAKDSEGIDIMLGVCANGLLIYRDRLRINRFAWPKIL
          240       250       260       270       280       290    

      340       350       360       370       380       390        
pF1KA0 KISYKRNNFYIKIRPGEFEQFESTIGFKLPNHRAAKRLWKVCVEHHTFFRLLLPEAPPKK
       ::::::.::::::::::.:::::::::::::::.::::::::.::::::::. :: ::: 
CCDS58 KISYKRSNFYIKIRPGEYEQFESTIGFKLPNHRSAKRLWKVCIEHHTFFRLVSPEPPPKG
          300       310       320       330       340       350    

      400       410       420       430       440       450        
pF1KA0 FLTLGSKFRYSGRTQAQTRRASALIDRPAPYFERSSSKRYTMSRSLDGEVGTGQYATTKG
       ::..:::::::::::::::.::::::::::.:::::::::::::::::    ....   .
CCDS58 FLVMGSKFRYSGRTQAQTRQASALIDRPAPFFERSSSKRYTMSRSLDG----AEFSRPAS
          360       370       380       390       400           410

      460       470       480       490       500       510        
pF1KA0 ISQTNLITTVTPEKKAEEERDEEEDKRRKGEEVTPISAIRHEGKSPGLGTDSCPLSPPST
       .:...    . :.   ..:  :   .: ..::    . .:   :   :   . : .    
CCDS58 VSENH---DAGPDGDKRDEDGESGGQRSEAEE----GEVRTPTKIKELKFLDKPEDVLLK
                 420       430           440       450       460   

      520       530       540         550       560        570     
pF1KA0 HCAPTSPTELRRRCKENDCKLPGYEPS--RAEHLPGEPALDSDGP-GRPYLGDQDVAFSY
       : :  : .::.:  :: . ::   . .  : ..::. ::  : .: : :  ... :    
CCDS58 HQA--SINELKRTLKEPNSKLIHRDRDWERERRLPSSPA--SPSPKGTPEKANEPVKTET
             470       480       490       500         510         

         580       590       600       610       620       630     
pF1KA0 RQQTGKGTTLFSFSLQLPESFPSLLDDDGYLSFPNLSETNLLPQSLQHYLPIRSPSLVPC
                                                                   
CCDS58 MTVSSLAIRKKIEPEAVLQTRVSAMDNTQQVDGSASVGREFIATTPSITTETISTTMENS
     520       530       540       550       560       570         

>--
 initn: 408 init1: 370 opt: 390  Z-score: 347.9  bits: 75.5 E(32554): 4.6e-13
Smith-Waterman score: 390; 46.6% identity (69.3% similar) in 176 aa overlap (911-1084:534-693)

              890       900       910       920       930       940
pF1KA0 AAQPAFTGIKGKEGSALTEGAKEEGGEEVAKAVLEQEETAAASRERQEEQSAAIHISETL
                                     .::: : ...: .  .: . ::..   : .
CCDS58 PKGTPEKANEPVKTETMTVSSLAIRKKIEPEAVL-QTRVSAMDNTQQVDGSASVG-REFI
           510       520       530        540       550        560 

              950       960       970       980       990          
pF1KA0 EQKPHFESSTVKTETISFGSVSPGGVKLEISTKEVPVVHTETKTITYESSQVDP--GTDL
          :     .. :::::  ..  ...:   : : . ..    .:.. :  ...:  : : 
CCDS58 ATTP-----SITTETIS--TTMENSLK---SGKGAAAMIPGPQTVATEIRSLSPIIGKD-
                  570         580          590       600       610 

     1000      1010      1020      1030      1040      1050        
pF1KA0 EPGVLMSAQTITSETTSTTTTTHITKTVKGGISETRIEKRIVITGDADIDHDQALAQAIK
          :: :.   :.:: ::.::::.:::::::.:::::::::.:::: :.:.::::: :::
CCDS58 ---VLTSTYGATAETLSTSTTTHVTKTVKGGFSETRIEKRIIITGDEDVDQDQALALAIK
                 620       630       640       650       660       

     1060      1070      1080            
pF1KA0 EAKEQHPDMSVTKVVVHKETEITPEDGED     
       ::: ::::: :::.::..::. .::.        
CCDS58 EAKLQHPDMLVTKAVVYRETDPSPEERDKKPQES
       670       680       690       700 

>>CCDS13272.1 EPB41L1 gene_id:2036|Hs108|chr20            (779 aa)
 initn: 2508 init1: 2037 opt: 2051  Z-score: 1814.6  bits: 347.0 E(32554): 9.4e-95
Smith-Waterman score: 2143; 43.4% identity (60.7% similar) in 1004 aa overlap (83-1084:8-771)

             60        70        80        90       100       110  
pF1KA0 AHSTPVRREVTDKEQEFAARAAKQLEYQQLEDDKLSQKSSSSKLSRSPLKIVKKPKSMQC
                                     : : ::.... :: ..:: ::.:: ::  :
CCDS13                        MEEKDYSEADGLSERTTPSKAQKSPQKIAKKYKSAIC
                                      10        20        30       

            120       130       140       150       160       170  
pF1KA0 KVILLDGSEYTCDVEKRSRGQVLFDKVCEHLNLLEKDYFGLTYRDAENQKNWLDPAKEIK
       .: :::.::: :.:::..::::::: ::::::::::::::::. ::..:::::::.::::
CCDS13 RVTLLDASEYECEVEKHGRGQVLFDLVCEHLNLLEKDYFGLTFCDADSQKNWLDPSKEIK
        40        50        60        70        80        90       

            180       190       200       210       220       230  
pF1KA0 KQVRSGAWHFSFNVKFYPPDPAQLSEDITRYYLCLQLRDDIVSGRLPCSFVTLALLGSYT
       ::.::. :.:.:.:::::::::::.::::::::::::: ::..::::::::: ::::::.
CCDS13 KQIRSSPWNFAFTVKFYPPDPAQLTEDITRYYLCLQLRADIITGRLPCSFVTHALLGSYA
       100       110       120       130       140       150       

            240       250       260       270       280       290  
pF1KA0 VQSELGDYDPDECGSDYISEFRFAPNHTKELEDKVIELHKSHRGMTPAEAEMHFLENAKK
       ::.:::::: .:  ..:.::.:::::.:.:::....::::..:::::.:::.::::::::
CCDS13 VQAELGDYDAEEHVGNYVSELRFAPNQTRELEERIMELHKTYRGMTPGEAEIHFLENAKK
       160       170       180       190       200       210       

            300       310       320       330       340       350  
pF1KA0 LSMYGVDLHHAKDSEGVEIMLGVCASGLLIYRDRLRINRFAWPKVLKISYKRNNFYIKIR
       ::::::::::::::::..:::::::.::::::::::::::::::.:::::::.:::::::
CCDS13 LSMYGVDLHHAKDSEGIDIMLGVCANGLLIYRDRLRINRFAWPKILKISYKRSNFYIKIR
       220       230       240       250       260       270       

            360       370       380       390       400       410  
pF1KA0 PGEFEQFESTIGFKLPNHRAAKRLWKVCVEHHTFFRLLLPEAPPKKFLTLGSKFRYSGRT
       :::.:::::::::::::::.::::::::.::::::::. :: ::: ::..::::::::::
CCDS13 PGEYEQFESTIGFKLPNHRSAKRLWKVCIEHHTFFRLVSPEPPPKGFLVMGSKFRYSGRT
       280       290       300       310       320       330       

            420       430       440       450       460       470  
pF1KA0 QAQTRRASALIDRPAPYFERSSSKRYTMSRSLDGEVGTGQYATTKGISQTNLITTVTPEK
       :::::.::::::::::.:::::::::::::::::    ....   ..:...    . :. 
CCDS13 QAQTRQASALIDRPAPFFERSSSKRYTMSRSLDG----AEFSRPASVSENH---DAGPDG
       340       350       360       370           380          390

            480       490       500       510       520       530  
pF1KA0 KAEEERDEEEDKRRKGEEVTPISAIRHEGKSPGLGTDSCPLSPPSTHCAPTSPTELRRRC
         ..:  :   .: ..::    . .:   :   :   . : .    : :  : .::.:  
CCDS13 DKRDEDGESGGQRSEAEE----GEVRTPTKIKELKFLDKPEDVLLKHQA--SINELKRTL
              400           410       420       430         440    

            540         550       560       570       580       590
pF1KA0 KENDCKLPGYEPS--RAEHLPGEPALDSDGPGRPYLGDQDVAFSYRQQTGKGTTLFSFSL
       :: . ::   . .  : ..::. ::  : .:                   :::       
CCDS13 KEPNSKLIHRDRDWERERRLPSSPA--SPSP-------------------KGT-------
          450       460         470                                

              600       610       620       630       640       650
pF1KA0 QLPESFPSLLDDDGYLSFPNLSETNLLPQSLQHYLPIRSPSLVPCFLFIFFFLLSASFSV
                                                                   
CCDS13 ------------------------------------------------------------
                                                                   

              660       670       680       690       700       710
pF1KA0 PYALTLSFPLALCLCYLEPKAASLSASLDNDPSDSSEEETDSERTDTAADGETTATESDQ
                         :. :.  :.:     ..:::..   :   : ...:   ..::
CCDS13 ------------------PEKANERAGL----REGSEEKVKPPRP-RAPESDTGDEDQDQ
                          480           490        500       510   

              720       730       740       750       760       770
pF1KA0 EEDAELKAQELEKTQDDLMKHQTNISELKRTFLETSTDTAVTNEWEKRLSTSPVRLAARQ
       :.:. .    :. ..  . .. ..:.  . . ::. .: .: ....          ..  
CCDS13 ERDTVF----LKDNHLAIERKCSSITVSSTSSLEAEVDFTVIGDYH----------GSAF
               520       530       540       550                   

              780       790       800       810       820       830
pF1KA0 EDAPMIEPLVPEETKQSSGEKLMDGSEIFSLLESARKPTEFIGGVTSTSQSWVQKMETKT
       ::     : . .. ..:. : :.     ::   .   :..                    
CCDS13 EDFSRSLPELDRDKSDSDTEGLL-----FSRDLNKGAPSQ------------------DD
     560       570       580            590                        

              840       850       860       870       880       890
pF1KA0 ESSGIETEPTVHHLPLSTEKVVQETVLVEERRVVHASGDASYSAGDSGDAAAQPAFTGIK
       ::.:::  :                    .:           .: .. :   .: :  .:
CCDS13 ESGGIEDSP--------------------DR-----------GACSTPD---MPQFEPVK
        600                                      610          620  

              900       910       920       930       940       950
pF1KA0 GKEGSALTEGAKEEGGEEVAKAVLEQEETAAASRERQEEQSAAIHISETLEQKPHFESST
        .  .. . . ...   :   :::. . .:  .   ::..  . . . ..   :.    :
CCDS13 TETMTVSSLAIRKKIEPE---AVLQTRVSAMDNT--QENSLKSGKGAAAMIPGPQ----T
            630       640          650         660       670       

              960       970       980       990      1000      1010
pF1KA0 VKTETISFGSVSPGGVKLEISTKEVPVVHTETKTITYESSQVDPGTDLEPGVLMSAQTIT
       : ::  :..                :..                : :    :: :.   :
CCDS13 VATEIRSLS----------------PII----------------GKD----VLTSTYGAT
           680                                           690       

             1020      1030      1040      1050      1060      1070
pF1KA0 SETTSTTTTTHITKTVKGGISETRIEKRIVITGDADIDHDQALAQAIKEAKEQHPDMSVT
       .:: ::.::::.:::::::.:::::::::.:::: :.:.::::: :::::: ::::: ::
CCDS13 AETLSTSTTTHVTKTVKGGFSETRIEKRIIITGDEDVDQDQALALAIKEAKLQHPDMLVT
       700       710       720       730       740       750       

             1080            
pF1KA0 KVVVHKETEITPEDGED     
       :.::..::. .::.        
CCDS13 KAVVYRETDPSPEERDKKPQES
       760       770         

>>CCDS59037.1 EPB41L2 gene_id:2037|Hs108|chr6             (747 aa)
 initn: 2409 init1: 1668 opt: 1943  Z-score: 1719.5  bits: 329.4 E(32554): 1.9e-89
Smith-Waterman score: 1947; 58.6% identity (80.1% similar) in 517 aa overlap (15-517:115-626)

                               10        20        30        40    
pF1KA0                 MTTESGSDSESKPDQEAEPQEAAGAQGRAGAPVPEPPKEEQQQA
                                     .:  :.:   :.: :   . .  .: . ..
CCDS59 QKSYTLVVAKDGGDKKEPTQAVVEEQVLDKEEPLPEEQRQAKGDA-EEMAQKKQEIKVEV
           90       100       110       120        130       140   

           50        60        70        80                90      
pF1KA0 LEQFAAAAAHSTPVRREVTDKEQEFAARAAKQLEYQQLEDDKL--------SQKSSSSKL
        :.  ... .  :   .:  .  :....  .. . .. ..:::        ... ....:
CCDS59 KEEKPSVSKEEKPSVSKVEMQPTELVSKE-REEKVKETQEDKLEGGAAKRETKEVQTNEL
           150       160       170        180       190       200  

          100       110       120       130       140       150    
pF1KA0 S--RSPLKIVKKPKSMQCKVILLDGSEYTCDVEKRSRGQVLFDKVCEHLNLLEKDYFGLT
       .  ..  :..:: :..:::: ::::.::.::.::...:::::::::::::::::::::: 
CCDS59 KAEKASQKVTKKTKTVQCKVTLLDGTEYSCDLEKHAKGQVLFDKVCEHLNLLEKDYFGLL
            210       220       230       240       250       260  

          160       170       180       190       200       210    
pF1KA0 YRDAENQKNWLDPAKEIKKQVRSGAWHFSFNVKFYPPDPAQLSEDITRYYLCLQLRDDIV
       .... .::::::::::::.:.:.  : :.::::::::::.::.::::::.::::::.::.
CCDS59 FQESPEQKNWLDPAKEIKRQLRNLPWLFTFNVKFYPPDPSQLTEDITRYFLCLQLRQDIA
            270       280       290       300       310       320  

          220       230       240       250       260       270    
pF1KA0 SGRLPCSFVTLALLGSYTVQSELGDYDPDECGSDYISEFRFAPNHTKELEDKVIELHKSH
       :::::::::: :::::::.:.:::::::.: ::  .:::.:::..:::::.:: ::::.:
CCDS59 SGRLPCSFVTHALLGSYTLQAELGDYDPEEHGSIDLSEFQFAPTQTKELEEKVAELHKTH
            330       340       350       360       370       380  

          280       290       300       310       320       330    
pF1KA0 RGMTPAEAEMHFLENAKKLSMYGVDLHHAKDSEGVEIMLGVCASGLLIYRDRLRINRFAW
       ::..::.:. .::::::.:::::::::::::::::.: :::::.:::::.::::::::::
CCDS59 RGLSPAQADSQFLENAKRLSMYGVDLHHAKDSEGVDIKLGVCANGLLIYKDRLRINRFAW
            390       400       410       420       430       440  

          340       350       360       370       380       390    
pF1KA0 PKVLKISYKRNNFYIKIRPGEFEQFESTIGFKLPNHRAAKRLWKVCVEHHTFFRLLLPEA
       ::.:::::::.:::::.::.:.::::::::::::::::::::::::::::::.::. :: 
CCDS59 PKILKISYKRSNFYIKVRPAELEQFESTIGFKLPNHRAAKRLWKVCVEHHTFYRLVSPEQ
            450       460       470       480       490       500  

           400       410       420       430       440        450  
pF1KA0 PPK-KFLTLGSKFRYSGRTQAQTRRASALIDRPAPYFERSSSKRYTMSRSLDGE-VGTGQ
       ::: ::::::::::::::::::::.::.:::::::.:::.::::  .::::::  .:. .
CCDS59 PPKAKFLTLGSKFRYSGRTQAQTRQASTLIDRPAPHFERTSSKR--VSRSLDGAPIGVMD
            510       520       530       540         550       560

             460       470       480       490        500       510
pF1KA0 YATTKGI-SQTNLITTVTPEKKAEEERDEEEDKRRKGEEVTPISAIRH-EGKSPGLGTDS
        .  : . . .. :..  :   .     .. : ::. .  :    ..  ::: : . :. 
CCDS59 QSLMKDFPGAAGEISAYGP-GLVSIAVVQDGDGRREVRSPTKAPHLQLIEGKPPVVKTEM
              570        580       590       600       610         

              520       530       540       550       560       570
pF1KA0 CPLSPPSTHCAPTSPTELRRRCKENDCKLPGYEPSRAEHLPGEPALDSDGPGRPYLGDQD
         .:  :                                                     
CCDS59 VTISDASQRTEISTKEVPIVQTETKTITYESPQIDGGAGGDSGTLLTAQTITSESVSTTT
     620       630       640       650       660       670         

>--
 initn: 636 init1: 584 opt: 599  Z-score: 532.1  bits: 109.7 E(32554): 2.5e-23
Smith-Waterman score: 599; 79.3% identity (94.2% similar) in 121 aa overlap (967-1087:628-747)

        940       950       960       970       980       990      
pF1KA0 SETLEQKPHFESSTVKTETISFGSVSPGGVKLEISTKEVPVVHTETKTITYESSQVDPGT
                                     . ::::::::.:.:::::::::: :.: :.
CCDS59 SPTKAPHLQLIEGKPPVVKTEMVTISDASQRTEISTKEVPIVQTETKTITYESPQIDGGA
       600       610       620       630       640       650       

       1000      1010      1020      1030      1040      1050      
pF1KA0 DLEPGVLMSAQTITSETTSTTTTTHITKTVKGGISETRIEKRIVITGDADIDHDQALAQA
         . :.:..:::::::..::::::::::::::::::::::::::::::.:::::::::::
CCDS59 GGDSGTLLTAQTITSESVSTTTTTHITKTVKGGISETRIEKRIVITGDGDIDHDQALAQA
       660       670       680       690       700       710       

       1060      1070      1080       
pF1KA0 IKEAKEQHPDMSVTKVVVHKETEITPEDGED
       :.::.:::::::::.::::::::.. :.:::
CCDS59 IREAREQHPDMSVTRVVVHKETELA-EEGED
       720       730       740        




1087 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 10:38:11 2016 done: Thu Nov  3 10:38:12 2016
 Total Scan time:  5.240 Total Display time:  0.420

Function used was FASTA [36.3.4 Apr, 2011]
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