Result of FASTA (omim) for pF1KA0815
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KA0815, 1229 aa
  1>>>pF1KA0815 1229 - 1229 aa - 1229 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.3724+/-0.000569; mu= 14.6733+/- 0.035
 mean_var=318.9808+/-64.457, 0's: 0 Z-trim(117.0): 644  B-trim: 71 in 1/52
 Lambda= 0.071811
 statistics sampled from 27940 (28713) to 27940 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.658), E-opt: 0.2 (0.337), width:  16
 Scan time: 13.340

The best scores are:                                      opt bits E(85289)
XP_006710469 (OMIM: 604266) PREDICTED: multiple ep (1436) 8125 857.8       0
NP_001400 (OMIM: 604266) multiple epidermal growth (1541) 7722 816.1       0
XP_011539188 (OMIM: 604266) PREDICTED: multiple ep (1560) 7722 816.1       0
XP_011539187 (OMIM: 604266) PREDICTED: multiple ep (1603) 7722 816.2       0
XP_011539190 (OMIM: 604266) PREDICTED: multiple ep (1364) 7707 814.5       0
XP_011539189 (OMIM: 604266) PREDICTED: multiple ep (1395) 7401 782.8       0
XP_016856022 (OMIM: 604266) PREDICTED: multiple ep (1559) 5473 583.1 4.7e-165
XP_016878162 (OMIM: 612454) PREDICTED: multiple ep (1021) 2348 259.1 1.1e-67
NP_115821 (OMIM: 612454) multiple epidermal growth (1044) 2348 259.1 1.1e-67
XP_016878161 (OMIM: 612454) PREDICTED: multiple ep (1044) 2348 259.1 1.1e-67
XP_016878160 (OMIM: 612454) PREDICTED: multiple ep (1092) 2348 259.2 1.1e-67
NP_001243474 (OMIM: 612453,614399) multiple epider (1140) 2331 257.4 3.9e-67
XP_011541996 (OMIM: 612453,614399) PREDICTED: mult (1140) 2331 257.4 3.9e-67
NP_115822 (OMIM: 612453,614399) multiple epidermal (1140) 2331 257.4 3.9e-67
XP_016865476 (OMIM: 612453,614399) PREDICTED: mult (1195) 2331 257.5   4e-67
XP_016856726 (OMIM: 610278) PREDICTED: platelet en ( 973) 2154 239.0 1.2e-61
XP_016856728 (OMIM: 610278) PREDICTED: platelet en ( 973) 2154 239.0 1.2e-61
XP_016856727 (OMIM: 610278) PREDICTED: platelet en ( 973) 2154 239.0 1.2e-61
XP_011507813 (OMIM: 610278) PREDICTED: platelet en (1002) 2154 239.0 1.2e-61
XP_011507812 (OMIM: 610278) PREDICTED: platelet en (1037) 2154 239.0 1.2e-61
XP_016856725 (OMIM: 610278) PREDICTED: platelet en (1037) 2154 239.0 1.2e-61
NP_001073940 (OMIM: 610278) platelet endothelial a (1037) 2154 239.0 1.2e-61
XP_005245198 (OMIM: 610278) PREDICTED: platelet en (1037) 2154 239.0 1.2e-61
XP_016856723 (OMIM: 610278) PREDICTED: platelet en (1125) 2154 239.1 1.3e-61
XP_016878159 (OMIM: 612454) PREDICTED: multiple ep (1097) 1965 219.5 9.8e-56
XP_016856729 (OMIM: 610278) PREDICTED: platelet en ( 909) 1954 218.2   2e-55
XP_016856730 (OMIM: 610278) PREDICTED: platelet en ( 909) 1954 218.2   2e-55
XP_016856731 (OMIM: 610278) PREDICTED: platelet en ( 909) 1954 218.2   2e-55
XP_016856724 (OMIM: 610278) PREDICTED: platelet en (1081) 1848 207.3 4.3e-52
XP_011507814 (OMIM: 610278) PREDICTED: platelet en ( 868) 1808 203.1 6.8e-51
XP_016878163 (OMIM: 612454) PREDICTED: multiple ep ( 854) 1342 154.8 2.3e-36
XP_016878164 (OMIM: 612454) PREDICTED: multiple ep ( 854) 1342 154.8 2.3e-36
NP_001295048 (OMIM: 612453,614399) multiple epider ( 567) 1288 148.9   9e-35
NP_001295050 (OMIM: 612453,614399) multiple epider ( 567) 1288 148.9   9e-35
XP_005259981 (OMIM: 125310,130720,600276,615293) P (2269) 1118 132.2 3.8e-29
XP_011517019 (OMIM: 109730,190198,616028) PREDICTE (2314) 1077 128.0 7.2e-28
NP_060087 (OMIM: 109730,190198,616028) neurogenic  (2555) 1077 128.1 7.6e-28
XP_016882866 (OMIM: 608529) PREDICTED: fibrillin-3 (1948) 1066 126.7 1.4e-27
NP_000129 (OMIM: 102370,129600,134797,154700,18490 (2871) 1062 126.6 2.4e-27
XP_016865477 (OMIM: 612453,614399) PREDICTED: mult ( 760)  986 117.8 2.8e-25
XP_016882864 (OMIM: 608529) PREDICTED: fibrillin-3 (2768)  993 119.4 3.3e-25
NP_000426 (OMIM: 125310,130720,600276,615293) neur (2321)  975 117.4 1.1e-24
XP_016882865 (OMIM: 608529) PREDICTED: fibrillin-3 (2766)  948 114.7 8.4e-24
XP_016882863 (OMIM: 608529) PREDICTED: fibrillin-3 (2777)  948 114.7 8.4e-24
XP_016882862 (OMIM: 608529) PREDICTED: fibrillin-3 (2789)  948 114.7 8.4e-24
XP_016882861 (OMIM: 608529) PREDICTED: fibrillin-3 (2809)  948 114.8 8.4e-24
NP_001308360 (OMIM: 608529) fibrillin-3 precursor  (2809)  948 114.8 8.4e-24
NP_115823 (OMIM: 608529) fibrillin-3 precursor [Ho (2809)  948 114.8 8.4e-24
XP_016882868 (OMIM: 608529) PREDICTED: fibrillin-3 (2851)  948 114.8 8.5e-24
XP_016864717 (OMIM: 121050,612570,616118) PREDICTE (2861)  932 113.1 2.7e-23


>>XP_006710469 (OMIM: 604266) PREDICTED: multiple epider  (1436 aa)
 initn: 9616 init1: 7674 opt: 8125  Z-score: 4569.5  bits: 857.8 E(85289):    0
Smith-Waterman score: 8738; 89.4% identity (89.6% similar) in 1261 aa overlap (1-1131:1-1261)

               10        20        30        40        50        60
pF1KA0 MGASRDRGLAALWCLGLLGGLARVAGTHYRYLWRGCYPCHLGQAGYPVSAGDQRPDVDEC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MGASRDRGLAALWCLGLLGGLARVAGTHYRYLWRGCYPCHLGQAGYPVSAGDQRPDVDEC
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 RTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRH
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 RCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACED
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 VDECAAGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VDECAAGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 CSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYRLSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYRLSA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 DGCGCEDVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DGCGCEDVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGEL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 PFVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PFVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCD
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 DCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRC
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 PPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWA
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 FGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGV
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 ACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRT
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 GEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPS
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 CQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAI
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 SGLCLCEAGYVGPRCEQQCPQGHFGPGCEQLCQCQHGAACDHVSGACTCPAGWRGTFCEH
       :::::::::::::::::::::::::::::: :::::::::::::::::::::::::::::
XP_006 SGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEH
              790       800       810       820       830       840

              850       860       870       880                    
pF1KA0 ACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAE-----------------
       :::::::::::::::::::::::::::::::::::::::::::                 
XP_006 ACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQACAC
              850       860       870       880       890       900

                                                                   
pF1KA0 ------------------------------------------------------------
                                                                   
XP_006 FNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPE
              910       920       930       940       950       960

                    890       900       910       920       930    
pF1KA0 ---------KCLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFG
                .::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFG
              970       980       990      1000      1010      1020

          940       950       960       970                        
pF1KA0 EACAQRCSCPPAAACHHVTGACRCPPGFTGSGCEQGCPPG--------------------
       :::::::::::.:::::::::::::::::::::::.::::                    
XP_006 EACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACH
             1030      1040      1050      1060      1070      1080

                                  980       990      1000      1010
pF1KA0 ------------------------RYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDC
                               ::::::::::::::::::::::::::::::::::::
XP_006 PATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDC
             1090      1100      1110      1120      1130      1140

             1020      1030      1040      1050      1060      1070
pF1KA0 NLTCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NLTCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTC
             1150      1160      1170      1180      1190      1200

             1080      1090      1100      1110      1120      1130
pF1KA0 SCRNGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SCRNGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRC
             1210      1220      1230      1240      1250      1260

             1140      1150      1160      1170      1180      1190
pF1KA0 GPGFYGQACEHRRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDGYMGPT
       :                                                           
XP_006 GPGFYGQACEHPCPPGFHGAGCQGLCWCQHGAPCDPISGRCLCPAGFHGHFCERGCEPGS
             1270      1280      1290      1300      1310      1320

>--
 initn: 1507 init1: 663 opt: 969  Z-score: 562.8  bits: 116.5 E(85289): 1.3e-24
Smith-Waterman score: 969; 67.4% identity (78.3% similar) in 184 aa overlap (1046-1229:1262-1436)

        1020      1030      1040      1050      1060      1070     
pF1KA0 QGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNG
                                     ::  :  ::. :: .  :.::.  : :..:
XP_006 PGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHG
            1240      1250      1260      1270      1280      1290 

        1080      1090      1100      1110      1120      1130     
pF1KA0 GLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFY
       . :   .: : :  :. :. :: .: :: .: .:: .:.: ... :.:.:: : : ::  
XP_006 APCDPISGRCLCPAGFHGHFCERGCEPGSFGEGCHQRCDCDGGAPCDPVTGLCLCPPG--
            1300      1310      1320      1330      1340           

        1140      1150      1160      1170      1180      1190     
pF1KA0 GQACEHRRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDGYMGPTCREGG
              :::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 -------RSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDGYMGPTCREGG
           1350      1360      1370      1380      1390      1400  

        1200      1210      1220         
pF1KA0 PLRLPENPSLAQGSAGTLPASSRPTSRSGGPARH
       ::::::::::::::::::::::::::::::::::
XP_006 PLRLPENPSLAQGSAGTLPASSRPTSRSGGPARH
           1410      1420      1430      

>>NP_001400 (OMIM: 604266) multiple epidermal growth fac  (1541 aa)
 initn: 9206 init1: 7264 opt: 7722  Z-score: 4343.6  bits: 816.1 E(85289):    0
Smith-Waterman score: 8335; 87.9% identity (88.3% similar) in 1225 aa overlap (38-1131:146-1366)

        10        20        30        40        50         60      
pF1KA0 GLAALWCLGLLGGLARVAGTHYRYLWRGCYPCHLGQAGYPVSAGDQ-RPDVDECRTHNGG
                                     :::      :   : . . :::::::::::
NP_001 QQPDEEGCLSAECSASLCFHGGRCVPGSAQPCHCP----PGFQGPRCQYDVDECRTHNGG
         120       130       140       150           160       170 

         70        80        90       100       110       120      
pF1KA0 CQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRP
             180       190       200       210       220       230 

        130       140       150       160       170       180      
pF1KA0 GFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAA
             240       250       260       270       280       290 

        190       200       210       220       230       240      
pF1KA0 GLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSA
             300       310       320       330       340       350 

        250       260       270       280       290       300      
pF1KA0 GPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCE
             360       370       380       390       400       410 

        310       320       330       340       350       360      
pF1KA0 DVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPL
             420       430       440       450       460       470 

        370       380       390       400       410       420      
pF1KA0 PHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCDDCRNGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCDDCRNGG
             480       490       500       510       520       530 

        430       440       450       460       470       480      
pF1KA0 TCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRCPPGVSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRCPPGVSG
             540       550       560       570       580       590 

        490       500       510       520       530       540      
pF1KA0 TNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCS
             600       610       620       630       640       650 

        550       560       570       580       590       600      
pF1KA0 EECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSVS
             660       670       680       690       700       710 

        610       620       630       640       650       660      
pF1KA0 GECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEA
             720       730       740       750       760       770 

        670       680       690       700       710       720      
pF1KA0 DCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCS
             780       790       800       810       820       830 

        730       740       750       760       770       780      
pF1KA0 CANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLC
             840       850       860       870       880       890 

        790       800       810       820       830       840      
pF1KA0 EAGYVGPRCEQQCPQGHFGPGCEQLCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGF
       :::::::::::::::::::::::: :::::::::::::::::::::::::::::::::::
NP_001 EAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGF
             900       910       920       930       940       950 

        850       860       870       880                          
pF1KA0 FGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAE-----------------------
       :::::::::::::::::::::::::::::::::::::                       
NP_001 FGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASC
             960       970       980       990      1000      1010 

                                                                   
pF1KA0 ------------------------------------------------------------
                                                                   
NP_001 DPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLA
            1020      1030      1040      1050      1060      1070 

              890       900       910       920       930       940
pF1KA0 ---KCLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQR
          .::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQR
            1080      1090      1100      1110      1120      1130 

              950       960       970                              
pF1KA0 CSCPPAAACHHVTGACRCPPGFTGSGCEQGCPPG--------------------------
       :::::.:::::::::::::::::::::::.::::                          
NP_001 CSCPPGAACHHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTC
            1140      1150      1160      1170      1180      1190 

                            980       990      1000      1010      
pF1KA0 ------------------RYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQ
                         ::::::::::::::::::::::::::::::::::::::::::
NP_001 SCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQ
            1200      1210      1220      1230      1240      1250 

       1020      1030      1040      1050      1060      1070      
pF1KA0 GRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGG
            1260      1270      1280      1290      1300      1310 

       1080      1090      1100      1110      1120      1130      
pF1KA0 LCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYG
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::     
NP_001 LCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYG
            1320      1330      1340      1350      1360      1370 

       1140      1150      1160      1170      1180      1190      
pF1KA0 QACEHRRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDGYMGPTCREGGP
                                                                   
NP_001 QACEHPCPPGFHGAGCQGLCWCQHGAPCDPISGRCLCPAGFHGHFCERGCEPGSFGEGCH
            1380      1390      1400      1410      1420      1430 

>--
 initn: 1507 init1: 663 opt: 969  Z-score: 562.5  bits: 116.5 E(85289): 1.4e-24
Smith-Waterman score: 969; 67.4% identity (78.3% similar) in 184 aa overlap (1046-1229:1367-1541)

        1020      1030      1040      1050      1060      1070     
pF1KA0 QGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNG
                                     ::  :  ::. :: .  :.::.  : :..:
NP_001 PGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHG
       1340      1350      1360      1370      1380      1390      

        1080      1090      1100      1110      1120      1130     
pF1KA0 GLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFY
       . :   .: : :  :. :. :: .: :: .: .:: .:.: ... :.:.:: : : ::  
NP_001 APCDPISGRCLCPAGFHGHFCERGCEPGSFGEGCHQRCDCDGGAPCDPVTGLCLCPPG--
       1400      1410      1420      1430      1440      1450      

        1140      1150      1160      1170      1180      1190     
pF1KA0 GQACEHRRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDGYMGPTCREGG
              :::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 -------RSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDGYMGPTCREGG
                1460      1470      1480      1490      1500       

        1200      1210      1220         
pF1KA0 PLRLPENPSLAQGSAGTLPASSRPTSRSGGPARH
       ::::::::::::::::::::::::::::::::::
NP_001 PLRLPENPSLAQGSAGTLPASSRPTSRSGGPARH
      1510      1520      1530      1540 

>>XP_011539188 (OMIM: 604266) PREDICTED: multiple epider  (1560 aa)
 initn: 7872 init1: 7264 opt: 7722  Z-score: 4343.5  bits: 816.1 E(85289):    0
Smith-Waterman score: 8335; 87.9% identity (88.3% similar) in 1225 aa overlap (38-1131:208-1428)

        10        20        30        40        50         60      
pF1KA0 GLAALWCLGLLGGLARVAGTHYRYLWRGCYPCHLGQAGYPVSAGDQ-RPDVDECRTHNGG
                                     :::      :   : . . :::::::::::
XP_011 QQPDEEGCLSAECSASLCFHGGRCVPGSAQPCHCP----PGFQGPRCQYDVDECRTHNGG
       180       190       200       210           220       230   

         70        80        90       100       110       120      
pF1KA0 CQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRP
           240       250       260       270       280       290   

        130       140       150       160       170       180      
pF1KA0 GFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAA
           300       310       320       330       340       350   

        190       200       210       220       230       240      
pF1KA0 GLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSA
           360       370       380       390       400       410   

        250       260       270       280       290       300      
pF1KA0 GPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCE
           420       430       440       450       460       470   

        310       320       330       340       350       360      
pF1KA0 DVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPL
           480       490       500       510       520       530   

        370       380       390       400       410       420      
pF1KA0 PHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCDDCRNGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCDDCRNGG
           540       550       560       570       580       590   

        430       440       450       460       470       480      
pF1KA0 TCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRCPPGVSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRCPPGVSG
           600       610       620       630       640       650   

        490       500       510       520       530       540      
pF1KA0 TNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCS
           660       670       680       690       700       710   

        550       560       570       580       590       600      
pF1KA0 EECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSVS
           720       730       740       750       760       770   

        610       620       630       640       650       660      
pF1KA0 GECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEA
           780       790       800       810       820       830   

        670       680       690       700       710       720      
pF1KA0 DCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCS
           840       850       860       870       880       890   

        730       740       750       760       770       780      
pF1KA0 CANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLC
           900       910       920       930       940       950   

        790       800       810       820       830       840      
pF1KA0 EAGYVGPRCEQQCPQGHFGPGCEQLCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGF
       :::::::::::::::::::::::: :::::::::::::::::::::::::::::::::::
XP_011 EAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGF
           960       970       980       990      1000      1010   

        850       860       870       880                          
pF1KA0 FGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAE-----------------------
       :::::::::::::::::::::::::::::::::::::                       
XP_011 FGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASC
          1020      1030      1040      1050      1060      1070   

                                                                   
pF1KA0 ------------------------------------------------------------
                                                                   
XP_011 DPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLA
          1080      1090      1100      1110      1120      1130   

              890       900       910       920       930       940
pF1KA0 ---KCLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQR
          .::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQR
          1140      1150      1160      1170      1180      1190   

              950       960       970                              
pF1KA0 CSCPPAAACHHVTGACRCPPGFTGSGCEQGCPPG--------------------------
       :::::.:::::::::::::::::::::::.::::                          
XP_011 CSCPPGAACHHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTC
          1200      1210      1220      1230      1240      1250   

                            980       990      1000      1010      
pF1KA0 ------------------RYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQ
                         ::::::::::::::::::::::::::::::::::::::::::
XP_011 SCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQ
          1260      1270      1280      1290      1300      1310   

       1020      1030      1040      1050      1060      1070      
pF1KA0 GRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGG
          1320      1330      1340      1350      1360      1370   

       1080      1090      1100      1110      1120      1130      
pF1KA0 LCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYG
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::     
XP_011 LCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYG
          1380      1390      1400      1410      1420      1430   

       1140      1150      1160      1170      1180      1190      
pF1KA0 QACEHRRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDGYMGPTCREGGP
                                                                   
XP_011 QACEHPCPPGFHGAGCQGLCWCQHGAPCDPISGRCLCPAGFHGHFCERDCRRGQFGPSCT
          1440      1450      1460      1470      1480      1490   

>--
 initn: 846 init1: 622 opt: 789  Z-score: 461.7  bits: 97.9 E(85289): 5.6e-19
Smith-Waterman score: 789; 72.9% identity (82.9% similar) in 140 aa overlap (1090-1229:1430-1560)

    1060      1070      1080      1090      1100      1110         
pF1KA0 NRFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNS
                                     :. :. ::  :::: .::.:.  : :....
XP_011 GRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHGA
    1400      1410      1420      1430      1440      1450         

    1120      1130      1140      1150      1160      1170         
pF1KA0 TCEPATGTCRCGPGFYGQACEHRRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQ
        :.: .: : :  ::.:. ::.         :::::::::::::::::::::::::::::
XP_011 PCDPISGRCLCPAGFHGHFCER---------DCRRGQFGPSCTLHCDCGGGADCDPVSGQ
    1460      1470      1480               1490      1500      1510

    1180      1190      1200      1210      1220         
pF1KA0 CHCVDGYMGPTCREGGPLRLPENPSLAQGSAGTLPASSRPTSRSGGPARH
       ::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CHCVDGYMGPTCREGGPLRLPENPSLAQGSAGTLPASSRPTSRSGGPARH
             1520      1530      1540      1550      1560

>>XP_011539187 (OMIM: 604266) PREDICTED: multiple epider  (1603 aa)
 initn: 9206 init1: 7264 opt: 7722  Z-score: 4343.4  bits: 816.2 E(85289):    0
Smith-Waterman score: 8335; 87.9% identity (88.3% similar) in 1225 aa overlap (38-1131:208-1428)

        10        20        30        40        50         60      
pF1KA0 GLAALWCLGLLGGLARVAGTHYRYLWRGCYPCHLGQAGYPVSAGDQ-RPDVDECRTHNGG
                                     :::      :   : . . :::::::::::
XP_011 QQPDEEGCLSAECSASLCFHGGRCVPGSAQPCHCP----PGFQGPRCQYDVDECRTHNGG
       180       190       200       210           220       230   

         70        80        90       100       110       120      
pF1KA0 CQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRP
           240       250       260       270       280       290   

        130       140       150       160       170       180      
pF1KA0 GFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAA
           300       310       320       330       340       350   

        190       200       210       220       230       240      
pF1KA0 GLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSA
           360       370       380       390       400       410   

        250       260       270       280       290       300      
pF1KA0 GPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCE
           420       430       440       450       460       470   

        310       320       330       340       350       360      
pF1KA0 DVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPL
           480       490       500       510       520       530   

        370       380       390       400       410       420      
pF1KA0 PHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCDDCRNGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCDDCRNGG
           540       550       560       570       580       590   

        430       440       450       460       470       480      
pF1KA0 TCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRCPPGVSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRCPPGVSG
           600       610       620       630       640       650   

        490       500       510       520       530       540      
pF1KA0 TNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCS
           660       670       680       690       700       710   

        550       560       570       580       590       600      
pF1KA0 EECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSVS
           720       730       740       750       760       770   

        610       620       630       640       650       660      
pF1KA0 GECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEA
           780       790       800       810       820       830   

        670       680       690       700       710       720      
pF1KA0 DCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCS
           840       850       860       870       880       890   

        730       740       750       760       770       780      
pF1KA0 CANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLC
           900       910       920       930       940       950   

        790       800       810       820       830       840      
pF1KA0 EAGYVGPRCEQQCPQGHFGPGCEQLCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGF
       :::::::::::::::::::::::: :::::::::::::::::::::::::::::::::::
XP_011 EAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGF
           960       970       980       990      1000      1010   

        850       860       870       880                          
pF1KA0 FGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAE-----------------------
       :::::::::::::::::::::::::::::::::::::                       
XP_011 FGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASC
          1020      1030      1040      1050      1060      1070   

                                                                   
pF1KA0 ------------------------------------------------------------
                                                                   
XP_011 DPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLA
          1080      1090      1100      1110      1120      1130   

              890       900       910       920       930       940
pF1KA0 ---KCLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQR
          .::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQR
          1140      1150      1160      1170      1180      1190   

              950       960       970                              
pF1KA0 CSCPPAAACHHVTGACRCPPGFTGSGCEQGCPPG--------------------------
       :::::.:::::::::::::::::::::::.::::                          
XP_011 CSCPPGAACHHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTC
          1200      1210      1220      1230      1240      1250   

                            980       990      1000      1010      
pF1KA0 ------------------RYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQ
                         ::::::::::::::::::::::::::::::::::::::::::
XP_011 SCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQ
          1260      1270      1280      1290      1300      1310   

       1020      1030      1040      1050      1060      1070      
pF1KA0 GRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGG
          1320      1330      1340      1350      1360      1370   

       1080      1090      1100      1110      1120      1130      
pF1KA0 LCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYG
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::     
XP_011 LCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYG
          1380      1390      1400      1410      1420      1430   

       1140      1150      1160      1170      1180      1190      
pF1KA0 QACEHRRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDGYMGPTCREGGP
                                                                   
XP_011 QACEHPCPPGFHGAGCQGLCWCQHGAPCDPISGRCLCPAGFHGHFCERGCEPGSFGEGCH
          1440      1450      1460      1470      1480      1490   

>--
 initn: 1507 init1: 663 opt: 969  Z-score: 562.4  bits: 116.5 E(85289): 1.4e-24
Smith-Waterman score: 969; 67.4% identity (78.3% similar) in 184 aa overlap (1046-1229:1429-1603)

        1020      1030      1040      1050      1060      1070     
pF1KA0 QGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNG
                                     ::  :  ::. :: .  :.::.  : :..:
XP_011 PGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHG
     1400      1410      1420      1430      1440      1450        

        1080      1090      1100      1110      1120      1130     
pF1KA0 GLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFY
       . :   .: : :  :. :. :: .: :: .: .:: .:.: ... :.:.:: : : ::  
XP_011 APCDPISGRCLCPAGFHGHFCERGCEPGSFGEGCHQRCDCDGGAPCDPVTGLCLCPPG--
     1460      1470      1480      1490      1500      1510        

        1140      1150      1160      1170      1180      1190     
pF1KA0 GQACEHRRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDGYMGPTCREGG
              :::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 -------RSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDGYMGPTCREGG
              1520      1530      1540      1550      1560         

        1200      1210      1220         
pF1KA0 PLRLPENPSLAQGSAGTLPASSRPTSRSGGPARH
       ::::::::::::::::::::::::::::::::::
XP_011 PLRLPENPSLAQGSAGTLPASSRPTSRSGGPARH
    1570      1580      1590      1600   

>>XP_011539190 (OMIM: 604266) PREDICTED: multiple epider  (1364 aa)
 initn: 7264 init1: 7264 opt: 7707  Z-score: 4335.7  bits: 814.5 E(85289):    0
Smith-Waterman score: 7724; 83.0% identity (88.4% similar) in 1174 aa overlap (38-1209:208-1362)

        10        20        30        40        50         60      
pF1KA0 GLAALWCLGLLGGLARVAGTHYRYLWRGCYPCHLGQAGYPVSAGDQ-RPDVDECRTHNGG
                                     :::      :   : . . :::::::::::
XP_011 QQPDEEGCLSAECSASLCFHGGRCVPGSAQPCHCP----PGFQGPRCQYDVDECRTHNGG
       180       190       200       210           220       230   

         70        80        90       100       110       120      
pF1KA0 CQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRP
           240       250       260       270       280       290   

        130       140       150       160       170       180      
pF1KA0 GFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAA
           300       310       320       330       340       350   

        190       200       210       220       230       240      
pF1KA0 GLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSA
           360       370       380       390       400       410   

        250       260       270       280       290       300      
pF1KA0 GPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCE
           420       430       440       450       460       470   

        310       320       330       340       350       360      
pF1KA0 DVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPL
           480       490       500       510       520       530   

        370       380       390       400       410       420      
pF1KA0 PHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCDDCRNGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCDDCRNGG
           540       550       560       570       580       590   

        430       440       450       460       470       480      
pF1KA0 TCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRCPPGVSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRCPPGVSG
           600       610       620       630       640       650   

        490       500       510       520       530       540      
pF1KA0 TNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCS
           660       670       680       690       700       710   

        550       560       570       580       590       600      
pF1KA0 EECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSVS
           720       730       740       750       760       770   

        610       620       630       640       650       660      
pF1KA0 GECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEA
           780       790       800       810       820       830   

        670       680       690       700       710       720      
pF1KA0 DCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCS
           840       850       860       870       880       890   

        730       740       750       760       770       780      
pF1KA0 CANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLC
           900       910       920       930       940       950   

        790       800       810       820       830       840      
pF1KA0 EAGYVGPRCEQQCPQGHFGPGCEQLCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGF
       :::::::::::::::::::::::: :::::::::::::::::::::::::::::::::::
XP_011 EAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGF
           960       970       980       990      1000      1010   

        850       860       870       880       890       900      
pF1KA0 FGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAEKCLPRDVRAGCRHSGGCLNGGLC
       ::::::::::::::::::::::::::::::::::::: :  .    .: .. .:.::. :
XP_011 FGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASC
          1020      1030      1040      1050      1060      1070   

        910       920       930       940       950       960      
pF1KA0 DPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPAAACHHVTGACRCPPGFTGSG
       ::  :.: :  :: : .: . :  : .:. : . : :  ...:  :.: : :: :..: .
XP_011 DPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLA
          1080      1090      1100      1110      1120      1130   

        970       980       990      1000      1010      1020      
pF1KA0 CEQGCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHV
       ::. : :     ::..  :::::: ::  :: : ::.:. :  :.  : .: ::  :.. 
XP_011 CEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQR
          1140      1150      1160      1170      1180      1190   

       1030      1040      1050      1060      1070       1080     
pF1KA0 CGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRN-GGLCHASNGSC
       :.:  ::::  :::.: :::: .:  ::..:: . ::  : . :.: . .  :: ..:.:
XP_011 CSCPPGAACHHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTC
          1200      1210      1220      1230      1240      1250   

        1090      1100      1110      1120      1130      1140     
pF1KA0 SCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHRRSG
       ::. :. :  :.  ::::::: .:.  :.: :...:. :::.:::  ::          :
XP_011 SCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFL---------G
          1260      1270      1280      1290      1300             

        1150      1160      1170      1180      1190      1200     
pF1KA0 ATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDGYMGPTCREGGPLRLPENPSL
       . ::: : .:.:::.::  : :: :: ::::.: : :  :  :  :.     :.:. :.:
XP_011 TDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCE-----RVPR-PGL
         1310      1320      1330      1340      1350              

        1210      1220         
pF1KA0 AQGSAGTLPASSRPTSRSGGPARH
       : ::                    
XP_011 ALGSLR                  
     1360                      

>>XP_011539189 (OMIM: 604266) PREDICTED: multiple epider  (1395 aa)
 initn: 8884 init1: 6942 opt: 7401  Z-score: 4164.3  bits: 782.8 E(85289):    0
Smith-Waterman score: 8324; 86.1% identity (86.4% similar) in 1261 aa overlap (1-1131:1-1220)

               10        20        30        40        50        60
pF1KA0 MGASRDRGLAALWCLGLLGGLARVAGTHYRYLWRGCYPCHLGQAGYPVSAGDQRPDVDEC
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::     
XP_011 MGASRDRGLAALWCLGLLGGLARVAGTHYRYLWRGCYPCHLGQAGYPVSAGDQRP-----
               10        20        30        40        50          

               70        80        90       100       110       120
pF1KA0 RTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRH
                                           ::::::::::::::::::::::::
XP_011 ------------------------------------AINSCALGNGGCQHHCVQLTITRH
                                              60        70         

              130       140       150       160       170       180
pF1KA0 RCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACED
      80        90       100       110       120       130         

              190       200       210       220       230       240
pF1KA0 VDECAAGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VDECAAGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHG
     140       150       160       170       180       190         

              250       260       270       280       290       300
pF1KA0 CSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYRLSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYRLSA
     200       210       220       230       240       250         

              310       320       330       340       350       360
pF1KA0 DGCGCEDVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DGCGCEDVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGEL
     260       270       280       290       300       310         

              370       380       390       400       410       420
pF1KA0 PFVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PFVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCD
     320       330       340       350       360       370         

              430       440       450       460       470       480
pF1KA0 DCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRC
     380       390       400       410       420       430         

              490       500       510       520       530       540
pF1KA0 PPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWA
     440       450       460       470       480       490         

              550       560       570       580       590       600
pF1KA0 FGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGV
     500       510       520       530       540       550         

              610       620       630       640       650       660
pF1KA0 ACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRT
     560       570       580       590       600       610         

              670       680       690       700       710       720
pF1KA0 GEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPS
     620       630       640       650       660       670         

              730       740       750       760       770       780
pF1KA0 CQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAI
     680       690       700       710       720       730         

              790       800       810       820       830       840
pF1KA0 SGLCLCEAGYVGPRCEQQCPQGHFGPGCEQLCQCQHGAACDHVSGACTCPAGWRGTFCEH
       :::::::::::::::::::::::::::::: :::::::::::::::::::::::::::::
XP_011 SGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEH
     740       750       760       770       780       790         

              850       860       870       880                    
pF1KA0 ACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAE-----------------
       :::::::::::::::::::::::::::::::::::::::::::                 
XP_011 ACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQACAC
     800       810       820       830       840       850         

                                                                   
pF1KA0 ------------------------------------------------------------
                                                                   
XP_011 FNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPE
     860       870       880       890       900       910         

                    890       900       910       920       930    
pF1KA0 ---------KCLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFG
                .::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFG
     920       930       940       950       960       970         

          940       950       960       970                        
pF1KA0 EACAQRCSCPPAAACHHVTGACRCPPGFTGSGCEQGCPPG--------------------
       :::::::::::.:::::::::::::::::::::::.::::                    
XP_011 EACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACH
     980       990      1000      1010      1020      1030         

                                  980       990      1000      1010
pF1KA0 ------------------------RYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDC
                               ::::::::::::::::::::::::::::::::::::
XP_011 PATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDC
    1040      1050      1060      1070      1080      1090         

             1020      1030      1040      1050      1060      1070
pF1KA0 NLTCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLTCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTC
    1100      1110      1120      1130      1140      1150         

             1080      1090      1100      1110      1120      1130
pF1KA0 SCRNGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SCRNGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRC
    1160      1170      1180      1190      1200      1210         

             1140      1150      1160      1170      1180      1190
pF1KA0 GPGFYGQACEHRRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDGYMGPT
       :                                                           
XP_011 GPGFYGQACEHPCPPGFHGAGCQGLCWCQHGAPCDPISGRCLCPAGFHGHFCERGCEPGS
    1220      1230      1240      1250      1260      1270         

>--
 initn: 1507 init1: 663 opt: 969  Z-score: 562.9  bits: 116.5 E(85289): 1.3e-24
Smith-Waterman score: 969; 67.4% identity (78.3% similar) in 184 aa overlap (1046-1229:1221-1395)

        1020      1030      1040      1050      1060      1070     
pF1KA0 QGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNG
                                     ::  :  ::. :: .  :.::.  : :..:
XP_011 PGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHG
             1200      1210      1220      1230      1240      1250

        1080      1090      1100      1110      1120      1130     
pF1KA0 GLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFY
       . :   .: : :  :. :. :: .: :: .: .:: .:.: ... :.:.:: : : ::  
XP_011 APCDPISGRCLCPAGFHGHFCERGCEPGSFGEGCHQRCDCDGGAPCDPVTGLCLCPPG--
             1260      1270      1280      1290      1300          

        1140      1150      1160      1170      1180      1190     
pF1KA0 GQACEHRRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDGYMGPTCREGG
              :::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 -------RSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDGYMGPTCREGG
            1310      1320      1330      1340      1350      1360 

        1200      1210      1220         
pF1KA0 PLRLPENPSLAQGSAGTLPASSRPTSRSGGPARH
       ::::::::::::::::::::::::::::::::::
XP_011 PLRLPENPSLAQGSAGTLPASSRPTSRSGGPARH
            1370      1380      1390     

>>XP_016856022 (OMIM: 604266) PREDICTED: multiple epider  (1559 aa)
 initn: 6201 init1: 4259 opt: 5473  Z-score: 3084.3  bits: 583.1 E(85289): 4.7e-165
Smith-Waterman score: 7875; 84.2% identity (84.7% similar) in 1225 aa overlap (38-1131:208-1384)

        10        20        30        40        50         60      
pF1KA0 GLAALWCLGLLGGLARVAGTHYRYLWRGCYPCHLGQAGYPVSAGDQ-RPDVDECRTHNGG
                                     :::      :   : . . :::::::::::
XP_016 QQPDEEGCLSAECSASLCFHGGRCVPGSAQPCHCP----PGFQGPRCQYDVDECRTHNGG
       180       190       200       210           220       230   

         70        80        90       100       110       120      
pF1KA0 CQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRP
           240       250       260       270       280       290   

        130       140       150       160       170       180      
pF1KA0 GFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAA
           300       310       320       330       340       350   

        190       200       210       220       230       240      
pF1KA0 GLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSA
           360       370       380       390       400       410   

        250       260       270       280       290       300      
pF1KA0 GPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCE
           420       430       440       450       460       470   

        310       320       330       340       350       360      
pF1KA0 DVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPL
           480       490       500       510       520       530   

        370       380       390       400       410       420      
pF1KA0 PHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCDDCRNGG
       ::::::::::::::::::::::::::::::::::::::.:                    
XP_016 PHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFAC--------------------
           540       550       560       570                       

        430       440       450       460       470       480      
pF1KA0 TCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRCPPGVSG
                               ::::::::::::::::::::::::::::::::::::
XP_016 ------------------------PPDTFGKNCSFSCSCQNGGTCDSVTGACRCPPGVSG
                                   580       590       600         

        490       500       510       520       530       540      
pF1KA0 TNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCS
     610       620       630       640       650       660         

        550       560       570       580       590       600      
pF1KA0 EECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSVS
     670       680       690       700       710       720         

        610       620       630       640       650       660      
pF1KA0 GECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEA
     730       740       750       760       770       780         

        670       680       690       700       710       720      
pF1KA0 DCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCS
     790       800       810       820       830       840         

        730       740       750       760       770       780      
pF1KA0 CANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLC
     850       860       870       880       890       900         

        790       800       810       820       830       840      
pF1KA0 EAGYVGPRCEQQCPQGHFGPGCEQLCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGF
       :::::::::::::::::::::::: :::::::::::::::::::::::::::::::::::
XP_016 EAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGF
     910       920       930       940       950       960         

        850       860       870       880                          
pF1KA0 FGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAE-----------------------
       :::::::::::::::::::::::::::::::::::::                       
XP_016 FGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASC
     970       980       990      1000      1010      1020         

                                                                   
pF1KA0 ------------------------------------------------------------
                                                                   
XP_016 DPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLA
    1030      1040      1050      1060      1070      1080         

              890       900       910       920       930       940
pF1KA0 ---KCLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQR
          .::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQR
    1090      1100      1110      1120      1130      1140         

              950       960       970                              
pF1KA0 CSCPPAAACHHVTGACRCPPGFTGSGCEQGCPPG--------------------------
       :::::.:::::::::::::::::::::::.::::                          
XP_016 CSCPPGAACHHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTC
    1150      1160      1170      1180      1190      1200         

                            980       990      1000      1010      
pF1KA0 ------------------RYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQ
                         ::::::::::::::::::::::::::::::::::::::::::
XP_016 SCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQ
    1210      1220      1230      1240      1250      1260         

       1020      1030      1040      1050      1060      1070      
pF1KA0 GRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGG
    1270      1280      1290      1300      1310      1320         

       1080      1090      1100      1110      1120      1130      
pF1KA0 LCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYG
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::     
XP_016 LCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYG
    1330      1340      1350      1360      1370      1380         

       1140      1150      1160      1170      1180      1190      
pF1KA0 QACEHRRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDGYMGPTCREGGP
                                                                   
XP_016 QACEHPCPPGFHGAGCQGLCWCQHGAPCDPISGRCLCPAGFHGHFCERGCEPGSFGEGCH
    1390      1400      1410      1420      1430      1440         

>--
 initn: 1507 init1: 663 opt: 969  Z-score: 562.5  bits: 116.5 E(85289): 1.4e-24
Smith-Waterman score: 969; 67.4% identity (78.3% similar) in 184 aa overlap (1046-1229:1385-1559)

        1020      1030      1040      1050      1060      1070     
pF1KA0 QGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNG
                                     ::  :  ::. :: .  :.::.  : :..:
XP_016 PGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHG
         1360      1370      1380      1390      1400      1410    

        1080      1090      1100      1110      1120      1130     
pF1KA0 GLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFY
       . :   .: : :  :. :. :: .: :: .: .:: .:.: ... :.:.:: : : ::  
XP_016 APCDPISGRCLCPAGFHGHFCERGCEPGSFGEGCHQRCDCDGGAPCDPVTGLCLCPPG--
         1420      1430      1440      1450      1460      1470    

        1140      1150      1160      1170      1180      1190     
pF1KA0 GQACEHRRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDGYMGPTCREGG
              :::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 -------RSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDGYMGPTCREGG
                  1480      1490      1500      1510      1520     

        1200      1210      1220         
pF1KA0 PLRLPENPSLAQGSAGTLPASSRPTSRSGGPARH
       ::::::::::::::::::::::::::::::::::
XP_016 PLRLPENPSLAQGSAGTLPASSRPTSRSGGPARH
        1530      1540      1550         

>>XP_016878162 (OMIM: 612454) PREDICTED: multiple epider  (1021 aa)
 initn: 2696 init1: 1026 opt: 2348  Z-score: 1336.3  bits: 259.1 E(85289): 1.1e-67
Smith-Waterman score: 2650; 40.8% identity (60.5% similar) in 812 aa overlap (341-1141:23-824)

              320       330       340       350       360       370
pF1KA0 CASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPLPHIA
                                     ::   ::  :   : .  .  ...:. .: 
XP_016         MVLSLTGLIAFSFLQATLALNPEDPNVCSHWESYAVTV--QESYAHPFDQIY
                       10        20        30          40        50

               380       390       400        410          420     
pF1KA0 VLQ-DELPQLFQDDDVGADEEEAELRGEHTLTEKFV-CLDDSF--GHDCSLTC-DDCRNG
         .  .. . :.      . . :  :: .:. ..   :    .  :  :   : ..: .:
XP_016 YTRCTDILNWFKCTRHRISYKTAYRRGLRTMYRRRSQCCPGYYESGDFCIPLCTEECVHG
               60        70        80        90       100       110

         430       440       450       460       470       480     
pF1KA0 GTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRCPPGVS
         :. . : : :  :: :  :.  :  : .: .::  :.::::. :. .:::: :  :  
XP_016 -RCV-SPDTCHCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNGALCNPITGACVCAAGFR
                120       130       140       150       160        

         490       500       510       520       530       540     
pF1KA0 GTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGC
       :  ::. :  : .:: :.  :.: . . :    : ::: ::  : .:.  ::: . :  :
XP_016 GWRCEELCAPGTHGKGCQLPCQCRHGASCDPRAGECLCAPGYTGVYCEELCPPGSHGAHC
      170       180       190       200       210       220        

         550       560       570       580       590       600     
pF1KA0 SEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSV
         .: : .  :  : .  : :.:  :. :  :   :  : :: .: : : :  :  :: :
XP_016 ELRCPCQNGGT--CHHITGECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQCDHV
      230         240       250       260       270       280      

         610       620       630       640        650       660    
pF1KA0 SGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSC-GGAPCHGVTGQCRCPPGRTGEDC
       .:.:  .: ::..:. : .::: :.:: .::. :.: .:. :  .:: :.: ::  :  :
XP_016 TGQC--HCTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPTTGACECEPGYKGPRC
        290         300       310       320       330       340    

           670       680         690       700       710       720 
pF1KA0 -EADCPEGRWGLGCQEICPACQ--HAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSC
        :  ::::  : ::   :: :.  ..  : : :::: : ::. : .:.. ::.:.:: .:
XP_016 QERLCPEGLHGPGCTLPCP-CDADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGC
          350       360        370       380       390       400   

             730       740       750       760       770       780 
pF1KA0 QTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAIS
       :  :.: : . ::  :: :.::::. :  :  .: .: .::.::  :.:. : :.:. ..
XP_016 QLPCTCQNGADCHSITGGCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNG-GTCSPVD
           410       420       430       440       450        460  

             790       800       810       820       830       840 
pF1KA0 GLCLCEAGYVGPRCEQQCPQGHFGPGCEQLCQCQHGAACDHVSGACTCPAGWRGTFCEHA
       : : :. :. :  :   ::.: .: .:.. : : .::::. ..:.:.:  :: :  ::  
XP_016 GSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELP
            470       480       490       500       510       520  

             850       860       870       880       890       900 
pF1KA0 CPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAEKCLPRDVRAGCRHSGGCL
       :: : :::.:   :.:. . .:: :.: : : ::  : ::   : :     .:  : .: 
XP_016 CPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCE
            530       540       550       560       570       580  

             910       920       930       940         950         
pF1KA0 NGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCS-CPPAA-ACHHVTGACRCP
       ::: :.:. : : :  :. :  ::  :  :..:..::: :  :  ..  :::..: :.: 
XP_016 NGGSCSPEDGSCECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRPCHHISGICECL
            590       600       610       620       630       640  

     960       970       980       990      1000      1010         
pF1KA0 PGFTGSGCEQGCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRF
       :::.:. :.: :  : .:  : :::.: :.:.:.   :.:.:  :..: ::. .:: : .
XP_016 PGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPIDGSCQCFPGWIGKDCSQACPPGFW
            650       660       670       680       690       700  

    1020      1030      1040      1050      1060      1070         
pF1KA0 GPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCH
       :: : :.:.: .::.:.   :.: : :: .:. : . ::   ::  : ..:.:.::. : 
XP_016 GPACFHACSCHNGASCSAEDGACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGASCD
            710       720       730       740       750       760  

    1080      1090      1100      1110      1120      1130         
pF1KA0 ASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQAC
         .:.:.:  :.::.:::  : :: .: .:.  : : :::::. .:::: :.::: :  :
XP_016 HISGKCTCRTGFTGQHCEQRCAPGTFGYGCQQLCECMNNSTCDHVTGTCYCSPGFKGIRC
            770       780       790       800       810       820  

    1140      1150      1160      1170      1180      1190         
pF1KA0 EHRRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDGYMGPTCREGGPLRL
       ..                                                          
XP_016 DQAALMMEELNPYTKISPALGAERHSVGAVTGIMLLLFLIVVLLGLFAWHRRRQKEKGRD
            830       840       850       860       870       880  

>>NP_115821 (OMIM: 612454) multiple epidermal growth fac  (1044 aa)
 initn: 1996 init1: 1040 opt: 2348  Z-score: 1336.2  bits: 259.1 E(85289): 1.1e-67
Smith-Waterman score: 2650; 40.8% identity (60.5% similar) in 812 aa overlap (341-1141:23-824)

              320       330       340       350       360       370
pF1KA0 CASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPLPHIA
                                     ::   ::  :   : .  .  ...:. .: 
NP_115         MVLSLTGLIAFSFLQATLALNPEDPNVCSHWESYAVTV--QESYAHPFDQIY
                       10        20        30          40        50

               380       390       400        410          420     
pF1KA0 VLQ-DELPQLFQDDDVGADEEEAELRGEHTLTEKFV-CLDDSF--GHDCSLTC-DDCRNG
         .  .. . :.      . . :  :: .:. ..   :    .  :  :   : ..: .:
NP_115 YTRCTDILNWFKCTRHRISYKTAYRRGLRTMYRRRSQCCPGYYESGDFCIPLCTEECVHG
               60        70        80        90       100       110

         430       440       450       460       470       480     
pF1KA0 GTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRCPPGVS
         :. . : : :  :: :  :.  :  : .: .::  :.::::. :. .:::: :  :  
NP_115 -RCV-SPDTCHCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNGALCNPITGACVCAAGFR
                120       130       140       150       160        

         490       500       510       520       530       540     
pF1KA0 GTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGC
       :  ::. :  : .:: :.  :.: . . :    : ::: ::  : .:.  ::: . :  :
NP_115 GWRCEELCAPGTHGKGCQLPCQCRHGASCDPRAGECLCAPGYTGVYCEELCPPGSHGAHC
      170       180       190       200       210       220        

         550       560       570       580       590       600     
pF1KA0 SEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSV
         .: : .  :  : .  : :.:  :. :  :   :  : :: .: : : :  :  :: :
NP_115 ELRCPCQNGGT--CHHITGECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQCDHV
      230         240       250       260       270       280      

         610       620       630       640        650       660    
pF1KA0 SGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSC-GGAPCHGVTGQCRCPPGRTGEDC
       .:.:  .: ::..:. : .::: :.:: .::. :.: .:. :  .:: :.: ::  :  :
NP_115 TGQC--HCTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPTTGACECEPGYKGPRC
        290         300       310       320       330       340    

           670       680         690       700       710       720 
pF1KA0 -EADCPEGRWGLGCQEICPACQ--HAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSC
        :  ::::  : ::   :: :.  ..  : : :::: : ::. : .:.. ::.:.:: .:
NP_115 QERLCPEGLHGPGCTLPCP-CDADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGC
          350       360        370       380       390       400   

             730       740       750       760       770       780 
pF1KA0 QTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAIS
       :  :.: : . ::  :: :.::::. :  :  .: .: .::.::  :.:. : :.:. ..
NP_115 QLPCTCQNGADCHSITGGCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNG-GTCSPVD
           410       420       430       440       450        460  

             790       800       810       820       830       840 
pF1KA0 GLCLCEAGYVGPRCEQQCPQGHFGPGCEQLCQCQHGAACDHVSGACTCPAGWRGTFCEHA
       : : :. :. :  :   ::.: .: .:.. : : .::::. ..:.:.:  :: :  ::  
NP_115 GSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELP
            470       480       490       500       510       520  

             850       860       870       880       890       900 
pF1KA0 CPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAEKCLPRDVRAGCRHSGGCL
       :: : :::.:   :.:. . .:: :.: : : ::  : ::   : :     .:  : .: 
NP_115 CPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCE
            530       540       550       560       570       580  

             910       920       930       940         950         
pF1KA0 NGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCS-CPPAA-ACHHVTGACRCP
       ::: :.:. : : :  :. :  ::  :  :..:..::: :  :  ..  :::..: :.: 
NP_115 NGGSCSPEDGSCECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRPCHHISGICECL
            590       600       610       620       630       640  

     960       970       980       990      1000      1010         
pF1KA0 PGFTGSGCEQGCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRF
       :::.:. :.: :  : .:  : :::.: :.:.:.   :.:.:  :..: ::. .:: : .
NP_115 PGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPIDGSCQCFPGWIGKDCSQACPPGFW
            650       660       670       680       690       700  

    1020      1030      1040      1050      1060      1070         
pF1KA0 GPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCH
       :: : :.:.: .::.:.   :.: : :: .:. : . ::   ::  : ..:.:.::. : 
NP_115 GPACFHACSCHNGASCSAEDGACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGASCD
            710       720       730       740       750       760  

    1080      1090      1100      1110      1120      1130         
pF1KA0 ASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQAC
         .:.:.:  :.::.:::  : :: .: .:.  : : :::::. .:::: :.::: :  :
NP_115 HISGKCTCRTGFTGQHCEQRCAPGTFGYGCQQLCECMNNSTCDHVTGTCYCSPGFKGIRC
            770       780       790       800       810       820  

    1140      1150      1160      1170      1180      1190         
pF1KA0 EHRRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDGYMGPTCREGGPLRL
       ..                                                          
NP_115 DQAALMMEELNPYTKISPALGAERHSVGAVTGIMLLLFLIVVLLGLFAWHRRRQKEKGRD
            830       840       850       860       870       880  

>>XP_016878161 (OMIM: 612454) PREDICTED: multiple epider  (1044 aa)
 initn: 1996 init1: 1040 opt: 2348  Z-score: 1336.2  bits: 259.1 E(85289): 1.1e-67
Smith-Waterman score: 2650; 40.8% identity (60.5% similar) in 812 aa overlap (341-1141:23-824)

              320       330       340       350       360       370
pF1KA0 CASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPLPHIA
                                     ::   ::  :   : .  .  ...:. .: 
XP_016         MVLSLTGLIAFSFLQATLALNPEDPNVCSHWESYAVTV--QESYAHPFDQIY
                       10        20        30          40        50

               380       390       400        410          420     
pF1KA0 VLQ-DELPQLFQDDDVGADEEEAELRGEHTLTEKFV-CLDDSF--GHDCSLTC-DDCRNG
         .  .. . :.      . . :  :: .:. ..   :    .  :  :   : ..: .:
XP_016 YTRCTDILNWFKCTRHRISYKTAYRRGLRTMYRRRSQCCPGYYESGDFCIPLCTEECVHG
               60        70        80        90       100       110

         430       440       450       460       470       480     
pF1KA0 GTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRCPPGVS
         :. . : : :  :: :  :.  :  : .: .::  :.::::. :. .:::: :  :  
XP_016 -RCV-SPDTCHCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNGALCNPITGACVCAAGFR
                120       130       140       150       160        

         490       500       510       520       530       540     
pF1KA0 GTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGC
       :  ::. :  : .:: :.  :.: . . :    : ::: ::  : .:.  ::: . :  :
XP_016 GWRCEELCAPGTHGKGCQLPCQCRHGASCDPRAGECLCAPGYTGVYCEELCPPGSHGAHC
      170       180       190       200       210       220        

         550       560       570       580       590       600     
pF1KA0 SEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSV
         .: : .  :  : .  : :.:  :. :  :   :  : :: .: : : :  :  :: :
XP_016 ELRCPCQNGGT--CHHITGECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQCDHV
      230         240       250       260       270       280      

         610       620       630       640        650       660    
pF1KA0 SGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSC-GGAPCHGVTGQCRCPPGRTGEDC
       .:.:  .: ::..:. : .::: :.:: .::. :.: .:. :  .:: :.: ::  :  :
XP_016 TGQC--HCTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPTTGACECEPGYKGPRC
        290         300       310       320       330       340    

           670       680         690       700       710       720 
pF1KA0 -EADCPEGRWGLGCQEICPACQ--HAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSC
        :  ::::  : ::   :: :.  ..  : : :::: : ::. : .:.. ::.:.:: .:
XP_016 QERLCPEGLHGPGCTLPCP-CDADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGC
          350       360        370       380       390       400   

             730       740       750       760       770       780 
pF1KA0 QTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAIS
       :  :.: : . ::  :: :.::::. :  :  .: .: .::.::  :.:. : :.:. ..
XP_016 QLPCTCQNGADCHSITGGCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNG-GTCSPVD
           410       420       430       440       450        460  

             790       800       810       820       830       840 
pF1KA0 GLCLCEAGYVGPRCEQQCPQGHFGPGCEQLCQCQHGAACDHVSGACTCPAGWRGTFCEHA
       : : :. :. :  :   ::.: .: .:.. : : .::::. ..:.:.:  :: :  ::  
XP_016 GSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELP
            470       480       490       500       510       520  

             850       860       870       880       890       900 
pF1KA0 CPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAEKCLPRDVRAGCRHSGGCL
       :: : :::.:   :.:. . .:: :.: : : ::  : ::   : :     .:  : .: 
XP_016 CPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCE
            530       540       550       560       570       580  

             910       920       930       940         950         
pF1KA0 NGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCS-CPPAA-ACHHVTGACRCP
       ::: :.:. : : :  :. :  ::  :  :..:..::: :  :  ..  :::..: :.: 
XP_016 NGGSCSPEDGSCECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRPCHHISGICECL
            590       600       610       620       630       640  

     960       970       980       990      1000      1010         
pF1KA0 PGFTGSGCEQGCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRF
       :::.:. :.: :  : .:  : :::.: :.:.:.   :.:.:  :..: ::. .:: : .
XP_016 PGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPIDGSCQCFPGWIGKDCSQACPPGFW
            650       660       670       680       690       700  

    1020      1030      1040      1050      1060      1070         
pF1KA0 GPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCH
       :: : :.:.: .::.:.   :.: : :: .:. : . ::   ::  : ..:.:.::. : 
XP_016 GPACFHACSCHNGASCSAEDGACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGASCD
            710       720       730       740       750       760  

    1080      1090      1100      1110      1120      1130         
pF1KA0 ASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQAC
         .:.:.:  :.::.:::  : :: .: .:.  : : :::::. .:::: :.::: :  :
XP_016 HISGKCTCRTGFTGQHCEQRCAPGTFGYGCQQLCECMNNSTCDHVTGTCYCSPGFKGIRC
            770       780       790       800       810       820  

    1140      1150      1160      1170      1180      1190         
pF1KA0 EHRRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDGYMGPTCREGGPLRL
       ..                                                          
XP_016 DQAALMMEELNPYTKISPALGAERHSVGAVTGIMLLLFLIVVLLGLFAWHRRRQKEKGRD
            830       840       850       860       870       880  




1229 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 10:21:20 2016 done: Thu Nov  3 10:21:22 2016
 Total Scan time: 13.340 Total Display time:  0.560

Function used was FASTA [36.3.4 Apr, 2011]
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