Result of FASTA (omim) for pF1KA0577
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KA0577, 1041 aa
  1>>>pF1KA0577 1041 - 1041 aa - 1041 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 10.9497+/-0.000612; mu= -4.6306+/- 0.038
 mean_var=395.1916+/-79.853, 0's: 0 Z-trim(116.3): 104  B-trim: 803 in 1/55
 Lambda= 0.064516
 statistics sampled from 27352 (27453) to 27352 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.649), E-opt: 0.2 (0.322), width:  16
 Scan time: 16.600

The best scores are:                                      opt bits E(85289)
NP_003578 (OMIM: 603405) putative pre-mRNA-splicin (1041) 6778 646.7 1.9e-184
NP_001157711 (OMIM: 603405) putative pre-mRNA-spli ( 981) 6323 604.4  1e-171
XP_011513240 (OMIM: 603405) PREDICTED: putative pr ( 742) 4866 468.6 5.6e-131
XP_011513241 (OMIM: 603405) PREDICTED: putative pr ( 742) 4866 468.6 5.6e-131
XP_011513242 (OMIM: 603405) PREDICTED: putative pr ( 560) 3474 339.0 4.6e-92
XP_011513243 (OMIM: 603405) PREDICTED: putative pr ( 524) 3464 338.0 8.3e-92
NP_001309145 (OMIM: 600396) ATP-dependent RNA heli ( 945) 2590 256.9 3.9e-67
NP_001309146 (OMIM: 600396) ATP-dependent RNA heli (1129) 2590 257.0 4.4e-67
NP_001309150 (OMIM: 600396) ATP-dependent RNA heli (1218) 2590 257.0 4.7e-67
NP_004932 (OMIM: 600396) ATP-dependent RNA helicas (1220) 2590 257.0 4.7e-67
NP_001309148 (OMIM: 600396) ATP-dependent RNA heli (1169) 2446 243.6 4.9e-63
NP_001309149 (OMIM: 600396) ATP-dependent RNA heli (1152) 2422 241.3 2.3e-62
NP_001309147 (OMIM: 600396) ATP-dependent RNA heli (1179) 2422 241.4 2.3e-62
NP_001289552 (OMIM: 600396) ATP-dependent RNA heli (1181) 2422 241.4 2.3e-62
NP_054722 (OMIM: 605584) pre-mRNA-splicing factor  (1227) 2331 232.9 8.5e-60
XP_011521786 (OMIM: 605584) PREDICTED: pre-mRNA-sp (1227) 2331 232.9 8.5e-60
XP_011521787 (OMIM: 605584) PREDICTED: pre-mRNA-sp (1227) 2331 232.9 8.5e-60
XP_016879402 (OMIM: 605584) PREDICTED: pre-mRNA-sp (1192) 2325 232.3 1.2e-59
XP_005256326 (OMIM: 605584) PREDICTED: pre-mRNA-sp (1192) 2325 232.3 1.2e-59
NP_001349 (OMIM: 603403) pre-mRNA-splicing factor  ( 795) 2076 209.0 8.7e-53
NP_064547 (OMIM: 614405) putative ATP-dependent RN ( 707) 1852 188.1 1.5e-46
NP_001186628 (OMIM: 614405) putative ATP-dependent ( 534) 1462 151.7   1e-35
XP_011525852 (OMIM: 615475) PREDICTED: probable AT (1143) 1131 121.2 3.4e-26
XP_011525853 (OMIM: 615475) PREDICTED: probable AT (1143) 1131 121.2 3.4e-26
XP_005259500 (OMIM: 615475) PREDICTED: probable AT (1143) 1131 121.2 3.4e-26
NP_055496 (OMIM: 615475) probable ATP-dependent RN (1143) 1131 121.2 3.4e-26
XP_016871894 (OMIM: 607960) PREDICTED: putative pr ( 743) 1096 117.7 2.4e-25
XP_016871893 (OMIM: 607960) PREDICTED: putative pr ( 743) 1096 117.7 2.4e-25
NP_060650 (OMIM: 607960) putative pre-mRNA-splicin ( 743) 1096 117.7 2.4e-25
XP_016880572 (OMIM: 607570) PREDICTED: probable AT ( 640)  876 97.2 3.1e-19
XP_016880571 (OMIM: 607570) PREDICTED: probable AT ( 640)  876 97.2 3.1e-19
XP_011523556 (OMIM: 607570) PREDICTED: probable AT ( 680)  876 97.2 3.3e-19
NP_001159773 (OMIM: 607570) probable ATP-dependent ( 702)  876 97.2 3.3e-19
XP_016880569 (OMIM: 607570) PREDICTED: probable AT ( 723)  876 97.2 3.4e-19
NP_078888 (OMIM: 607570) probable ATP-dependent RN ( 779)  876 97.3 3.6e-19
XP_011523555 (OMIM: 607570) PREDICTED: probable AT ( 718)  660 77.1 3.8e-13
XP_016880366 (OMIM: 614405) PREDICTED: putative AT ( 279)  646 75.4 4.8e-13
NP_065916 (OMIM: 612767) ATP-dependent RNA helicas (1008)  644 75.8 1.4e-12
XP_016880570 (OMIM: 607570) PREDICTED: probable AT ( 653)  597 71.2 2.1e-11
XP_006722146 (OMIM: 607570) PREDICTED: probable AT ( 752)  597 71.3 2.3e-11
NP_001107869 (OMIM: 612767) ATP-dependent RNA heli ( 994)  574 69.3 1.2e-10
XP_016865224 (OMIM: 616530) PREDICTED: probable AT ( 971)  545 66.6 7.9e-10
NP_001332905 (OMIM: 616530) probable ATP-dependent (1130)  545 66.6 8.8e-10
XP_016865222 (OMIM: 616530) PREDICTED: probable AT (1139)  545 66.6 8.9e-10
XP_011541888 (OMIM: 616530) PREDICTED: probable AT (1162)  545 66.6   9e-10
NP_001332904 (OMIM: 616530) probable ATP-dependent (1268)  545 66.7 9.5e-10
XP_016865220 (OMIM: 616530) PREDICTED: probable AT (1277)  545 66.7 9.6e-10
XP_011541884 (OMIM: 616530) PREDICTED: probable AT (1406)  545 66.7   1e-09
NP_073739 (OMIM: 616530) probable ATP-dependent RN (1430)  545 66.7   1e-09
XP_016865219 (OMIM: 616530) PREDICTED: probable AT (1430)  545 66.7   1e-09


>>NP_003578 (OMIM: 603405) putative pre-mRNA-splicing fa  (1041 aa)
 initn: 6778 init1: 6778 opt: 6778  Z-score: 3432.5  bits: 646.7 E(85289): 1.9e-184
Smith-Waterman score: 6778; 100.0% identity (100.0% similar) in 1041 aa overlap (1-1041:1-1041)

               10        20        30        40        50        60
pF1KA0 MATPAGLERWVQDELHSVLGLSERHVAQFLIGTAQRCTSAEEFVQRLRDTDTLDLSGPAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MATPAGLERWVQDELHSVLGLSERHVAQFLIGTAQRCTSAEEFVQRLRDTDTLDLSGPAR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 DFALRLWNKVPRKAVVEKPARAAEREARALLEKNRSYRLLEDSEESSEETVSRAGSSLQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DFALRLWNKVPRKAVVEKPARAAEREARALLEKNRSYRLLEDSEESSEETVSRAGSSLQK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 KRKKRKHLRKKREEEEEEEASEKGKKKTGGSKQQTEKPESEDEWERTERERLQDLEERDA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KRKKRKHLRKKREEEEEEEASEKGKKKTGGSKQQTEKPESEDEWERTERERLQDLEERDA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 FAERVRQRDKDRTRNVLERSDKKAYEEAQKRLKMAEEDRKAMVPELRKKSRREYLAKRER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 FAERVRQRDKDRTRNVLERSDKKAYEEAQKRLKMAEEDRKAMVPELRKKSRREYLAKRER
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 EKLEDLEAELADEEFLFGDVELSRHERQELKYKRRVRDLAREYRAAGEQEKLEATNRYHM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EKLEDLEAELADEEFLFGDVELSRHERQELKYKRRVRDLAREYRAAGEQEKLEATNRYHM
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 PKETRGQPARAVDLVEEESGAPGEEQRRWEEARLGAASLKFGARDAASQEPKYQLVLEEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PKETRGQPARAVDLVEEESGAPGEEQRRWEEARLGAASLKFGARDAASQEPKYQLVLEEE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 ETIEFVRATQLQGDEEPSAPPTSTQAQQKESIQAVRRSLPVFPFREELLAAIANHQVLII
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ETIEFVRATQLQGDEEPSAPPTSTQAQQKESIQAVRRSLPVFPFREELLAAIANHQVLII
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 EGETGSGKTTQIPQYLFEEGYTNKGMKIACTQPRRVAAMSVAARVAREMGVKLGNEVGYS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EGETGSGKTTQIPQYLFEEGYTNKGMKIACTQPRRVAAMSVAARVAREMGVKLGNEVGYS
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 IRFEDCTSERTVLRYMTDGMLLREFLSEPDLASYSVVMVDEAHERTLHTDILFGLIKDVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 IRFEDCTSERTVLRYMTDGMLLREFLSEPDLASYSVVMVDEAHERTLHTDILFGLIKDVA
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 RFRPELKVLVASATMDTARFSTFFDDAPVFRIPGRRFPVDIFYTKAPEADYLEACVVSVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 RFRPELKVLVASATMDTARFSTFFDDAPVFRIPGRRFPVDIFYTKAPEADYLEACVVSVL
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 QIHVTQPPGDILVFLTGQEEIEAACEMLQDRCRRLGSKIRELLVLPIYANLPSDMQARIF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QIHVTQPPGDILVFLTGQEEIEAACEMLQDRCRRLGSKIRELLVLPIYANLPSDMQARIF
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 QPTPPGARKVVVATNIAETSLTIEGIIYVLDPGFCKQKSYNPRTGMESLTVTPCSKASAN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QPTPPGARKVVVATNIAETSLTIEGIIYVLDPGFCKQKSYNPRTGMESLTVTPCSKASAN
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 QRAGRAGRVAAGKCFRLYTAWAYQHELEETTVPEIQRTSLGNVVLLLKSLGIHDLMHFDF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QRAGRAGRVAAGKCFRLYTAWAYQHELEETTVPEIQRTSLGNVVLLLKSLGIHDLMHFDF
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 LDPPPYETLLLALEQLYALGALNHLGELTTSGRKMAELPVDPMLSKMILASEKYSCSEEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LDPPPYETLLLALEQLYALGALNHLGELTTSGRKMAELPVDPMLSKMILASEKYSCSEEI
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA0 LTVAAMLSVNNSIFYRPKDKVVHADNARVNFFLPGGDHLVLLNVYTQWAESGYSSQWCYE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LTVAAMLSVNNSIFYRPKDKVVHADNARVNFFLPGGDHLVLLNVYTQWAESGYSSQWCYE
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA0 NFVQFRSMRRARDVREQLEGLLERVEVGLSSCQGDYIRVRKAITAGYFYHTARLTRSGYR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 NFVQFRSMRRARDVREQLEGLLERVEVGLSSCQGDYIRVRKAITAGYFYHTARLTRSGYR
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KA0 TVKQQQTVFIHPNSSLFEQQPRWLLYHELVLTTKEFMRQVLEIESSWLLEVAPHYYKAKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 TVKQQQTVFIHPNSSLFEQQPRWLLYHELVLTTKEFMRQVLEIESSWLLEVAPHYYKAKE
              970       980       990      1000      1010      1020

             1030      1040 
pF1KA0 LEDPHAKKMPKKIGKTREELG
       :::::::::::::::::::::
NP_003 LEDPHAKKMPKKIGKTREELG
             1030      1040 

>>NP_001157711 (OMIM: 603405) putative pre-mRNA-splicing  (981 aa)
 initn: 6323 init1: 6323 opt: 6323  Z-score: 3203.9  bits: 604.4 E(85289): 1e-171
Smith-Waterman score: 6323; 100.0% identity (100.0% similar) in 973 aa overlap (69-1041:9-981)

       40        50        60        70        80        90        
pF1KA0 SAEEFVQRLRDTDTLDLSGPARDFALRLWNKVPRKAVVEKPARAAEREARALLEKNRSYR
                                     ::::::::::::::::::::::::::::::
NP_001                       MSEDPRGPKVPRKAVVEKPARAAEREARALLEKNRSYR
                                     10        20        30        

      100       110       120       130       140       150        
pF1KA0 LLEDSEESSEETVSRAGSSLQKKRKKRKHLRKKREEEEEEEASEKGKKKTGGSKQQTEKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLEDSEESSEETVSRAGSSLQKKRKKRKHLRKKREEEEEEEASEKGKKKTGGSKQQTEKP
       40        50        60        70        80        90        

      160       170       180       190       200       210        
pF1KA0 ESEDEWERTERERLQDLEERDAFAERVRQRDKDRTRNVLERSDKKAYEEAQKRLKMAEED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESEDEWERTERERLQDLEERDAFAERVRQRDKDRTRNVLERSDKKAYEEAQKRLKMAEED
      100       110       120       130       140       150        

      220       230       240       250       260       270        
pF1KA0 RKAMVPELRKKSRREYLAKREREKLEDLEAELADEEFLFGDVELSRHERQELKYKRRVRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RKAMVPELRKKSRREYLAKREREKLEDLEAELADEEFLFGDVELSRHERQELKYKRRVRD
      160       170       180       190       200       210        

      280       290       300       310       320       330        
pF1KA0 LAREYRAAGEQEKLEATNRYHMPKETRGQPARAVDLVEEESGAPGEEQRRWEEARLGAAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAREYRAAGEQEKLEATNRYHMPKETRGQPARAVDLVEEESGAPGEEQRRWEEARLGAAS
      220       230       240       250       260       270        

      340       350       360       370       380       390        
pF1KA0 LKFGARDAASQEPKYQLVLEEEETIEFVRATQLQGDEEPSAPPTSTQAQQKESIQAVRRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKFGARDAASQEPKYQLVLEEEETIEFVRATQLQGDEEPSAPPTSTQAQQKESIQAVRRS
      280       290       300       310       320       330        

      400       410       420       430       440       450        
pF1KA0 LPVFPFREELLAAIANHQVLIIEGETGSGKTTQIPQYLFEEGYTNKGMKIACTQPRRVAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPVFPFREELLAAIANHQVLIIEGETGSGKTTQIPQYLFEEGYTNKGMKIACTQPRRVAA
      340       350       360       370       380       390        

      460       470       480       490       500       510        
pF1KA0 MSVAARVAREMGVKLGNEVGYSIRFEDCTSERTVLRYMTDGMLLREFLSEPDLASYSVVM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSVAARVAREMGVKLGNEVGYSIRFEDCTSERTVLRYMTDGMLLREFLSEPDLASYSVVM
      400       410       420       430       440       450        

      520       530       540       550       560       570        
pF1KA0 VDEAHERTLHTDILFGLIKDVARFRPELKVLVASATMDTARFSTFFDDAPVFRIPGRRFP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VDEAHERTLHTDILFGLIKDVARFRPELKVLVASATMDTARFSTFFDDAPVFRIPGRRFP
      460       470       480       490       500       510        

      580       590       600       610       620       630        
pF1KA0 VDIFYTKAPEADYLEACVVSVLQIHVTQPPGDILVFLTGQEEIEAACEMLQDRCRRLGSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VDIFYTKAPEADYLEACVVSVLQIHVTQPPGDILVFLTGQEEIEAACEMLQDRCRRLGSK
      520       530       540       550       560       570        

      640       650       660       670       680       690        
pF1KA0 IRELLVLPIYANLPSDMQARIFQPTPPGARKVVVATNIAETSLTIEGIIYVLDPGFCKQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IRELLVLPIYANLPSDMQARIFQPTPPGARKVVVATNIAETSLTIEGIIYVLDPGFCKQK
      580       590       600       610       620       630        

      700       710       720       730       740       750        
pF1KA0 SYNPRTGMESLTVTPCSKASANQRAGRAGRVAAGKCFRLYTAWAYQHELEETTVPEIQRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SYNPRTGMESLTVTPCSKASANQRAGRAGRVAAGKCFRLYTAWAYQHELEETTVPEIQRT
      640       650       660       670       680       690        

      760       770       780       790       800       810        
pF1KA0 SLGNVVLLLKSLGIHDLMHFDFLDPPPYETLLLALEQLYALGALNHLGELTTSGRKMAEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLGNVVLLLKSLGIHDLMHFDFLDPPPYETLLLALEQLYALGALNHLGELTTSGRKMAEL
      700       710       720       730       740       750        

      820       830       840       850       860       870        
pF1KA0 PVDPMLSKMILASEKYSCSEEILTVAAMLSVNNSIFYRPKDKVVHADNARVNFFLPGGDH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVDPMLSKMILASEKYSCSEEILTVAAMLSVNNSIFYRPKDKVVHADNARVNFFLPGGDH
      760       770       780       790       800       810        

      880       890       900       910       920       930        
pF1KA0 LVLLNVYTQWAESGYSSQWCYENFVQFRSMRRARDVREQLEGLLERVEVGLSSCQGDYIR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVLLNVYTQWAESGYSSQWCYENFVQFRSMRRARDVREQLEGLLERVEVGLSSCQGDYIR
      820       830       840       850       860       870        

      940       950       960       970       980       990        
pF1KA0 VRKAITAGYFYHTARLTRSGYRTVKQQQTVFIHPNSSLFEQQPRWLLYHELVLTTKEFMR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VRKAITAGYFYHTARLTRSGYRTVKQQQTVFIHPNSSLFEQQPRWLLYHELVLTTKEFMR
      880       890       900       910       920       930        

     1000      1010      1020      1030      1040 
pF1KA0 QVLEIESSWLLEVAPHYYKAKELEDPHAKKMPKKIGKTREELG
       :::::::::::::::::::::::::::::::::::::::::::
NP_001 QVLEIESSWLLEVAPHYYKAKELEDPHAKKMPKKIGKTREELG
      940       950       960       970       980 

>>XP_011513240 (OMIM: 603405) PREDICTED: putative pre-mR  (742 aa)
 initn: 4866 init1: 4866 opt: 4866  Z-score: 2472.5  bits: 468.6 E(85289): 5.6e-131
Smith-Waterman score: 4866; 100.0% identity (100.0% similar) in 742 aa overlap (300-1041:1-742)

     270       280       290       300       310       320         
pF1KA0 LKYKRRVRDLAREYRAAGEQEKLEATNRYHMPKETRGQPARAVDLVEEESGAPGEEQRRW
                                     ::::::::::::::::::::::::::::::
XP_011                               MPKETRGQPARAVDLVEEESGAPGEEQRRW
                                             10        20        30

     330       340       350       360       370       380         
pF1KA0 EEARLGAASLKFGARDAASQEPKYQLVLEEEETIEFVRATQLQGDEEPSAPPTSTQAQQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEARLGAASLKFGARDAASQEPKYQLVLEEEETIEFVRATQLQGDEEPSAPPTSTQAQQK
               40        50        60        70        80        90

     390       400       410       420       430       440         
pF1KA0 ESIQAVRRSLPVFPFREELLAAIANHQVLIIEGETGSGKTTQIPQYLFEEGYTNKGMKIA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESIQAVRRSLPVFPFREELLAAIANHQVLIIEGETGSGKTTQIPQYLFEEGYTNKGMKIA
              100       110       120       130       140       150

     450       460       470       480       490       500         
pF1KA0 CTQPRRVAAMSVAARVAREMGVKLGNEVGYSIRFEDCTSERTVLRYMTDGMLLREFLSEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CTQPRRVAAMSVAARVAREMGVKLGNEVGYSIRFEDCTSERTVLRYMTDGMLLREFLSEP
              160       170       180       190       200       210

     510       520       530       540       550       560         
pF1KA0 DLASYSVVMVDEAHERTLHTDILFGLIKDVARFRPELKVLVASATMDTARFSTFFDDAPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLASYSVVMVDEAHERTLHTDILFGLIKDVARFRPELKVLVASATMDTARFSTFFDDAPV
              220       230       240       250       260       270

     570       580       590       600       610       620         
pF1KA0 FRIPGRRFPVDIFYTKAPEADYLEACVVSVLQIHVTQPPGDILVFLTGQEEIEAACEMLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FRIPGRRFPVDIFYTKAPEADYLEACVVSVLQIHVTQPPGDILVFLTGQEEIEAACEMLQ
              280       290       300       310       320       330

     630       640       650       660       670       680         
pF1KA0 DRCRRLGSKIRELLVLPIYANLPSDMQARIFQPTPPGARKVVVATNIAETSLTIEGIIYV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DRCRRLGSKIRELLVLPIYANLPSDMQARIFQPTPPGARKVVVATNIAETSLTIEGIIYV
              340       350       360       370       380       390

     690       700       710       720       730       740         
pF1KA0 LDPGFCKQKSYNPRTGMESLTVTPCSKASANQRAGRAGRVAAGKCFRLYTAWAYQHELEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDPGFCKQKSYNPRTGMESLTVTPCSKASANQRAGRAGRVAAGKCFRLYTAWAYQHELEE
              400       410       420       430       440       450

     750       760       770       780       790       800         
pF1KA0 TTVPEIQRTSLGNVVLLLKSLGIHDLMHFDFLDPPPYETLLLALEQLYALGALNHLGELT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TTVPEIQRTSLGNVVLLLKSLGIHDLMHFDFLDPPPYETLLLALEQLYALGALNHLGELT
              460       470       480       490       500       510

     810       820       830       840       850       860         
pF1KA0 TSGRKMAELPVDPMLSKMILASEKYSCSEEILTVAAMLSVNNSIFYRPKDKVVHADNARV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSGRKMAELPVDPMLSKMILASEKYSCSEEILTVAAMLSVNNSIFYRPKDKVVHADNARV
              520       530       540       550       560       570

     870       880       890       900       910       920         
pF1KA0 NFFLPGGDHLVLLNVYTQWAESGYSSQWCYENFVQFRSMRRARDVREQLEGLLERVEVGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NFFLPGGDHLVLLNVYTQWAESGYSSQWCYENFVQFRSMRRARDVREQLEGLLERVEVGL
              580       590       600       610       620       630

     930       940       950       960       970       980         
pF1KA0 SSCQGDYIRVRKAITAGYFYHTARLTRSGYRTVKQQQTVFIHPNSSLFEQQPRWLLYHEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSCQGDYIRVRKAITAGYFYHTARLTRSGYRTVKQQQTVFIHPNSSLFEQQPRWLLYHEL
              640       650       660       670       680       690

     990      1000      1010      1020      1030      1040 
pF1KA0 VLTTKEFMRQVLEIESSWLLEVAPHYYKAKELEDPHAKKMPKKIGKTREELG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLTTKEFMRQVLEIESSWLLEVAPHYYKAKELEDPHAKKMPKKIGKTREELG
              700       710       720       730       740  

>>XP_011513241 (OMIM: 603405) PREDICTED: putative pre-mR  (742 aa)
 initn: 4866 init1: 4866 opt: 4866  Z-score: 2472.5  bits: 468.6 E(85289): 5.6e-131
Smith-Waterman score: 4866; 100.0% identity (100.0% similar) in 742 aa overlap (300-1041:1-742)

     270       280       290       300       310       320         
pF1KA0 LKYKRRVRDLAREYRAAGEQEKLEATNRYHMPKETRGQPARAVDLVEEESGAPGEEQRRW
                                     ::::::::::::::::::::::::::::::
XP_011                               MPKETRGQPARAVDLVEEESGAPGEEQRRW
                                             10        20        30

     330       340       350       360       370       380         
pF1KA0 EEARLGAASLKFGARDAASQEPKYQLVLEEEETIEFVRATQLQGDEEPSAPPTSTQAQQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEARLGAASLKFGARDAASQEPKYQLVLEEEETIEFVRATQLQGDEEPSAPPTSTQAQQK
               40        50        60        70        80        90

     390       400       410       420       430       440         
pF1KA0 ESIQAVRRSLPVFPFREELLAAIANHQVLIIEGETGSGKTTQIPQYLFEEGYTNKGMKIA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESIQAVRRSLPVFPFREELLAAIANHQVLIIEGETGSGKTTQIPQYLFEEGYTNKGMKIA
              100       110       120       130       140       150

     450       460       470       480       490       500         
pF1KA0 CTQPRRVAAMSVAARVAREMGVKLGNEVGYSIRFEDCTSERTVLRYMTDGMLLREFLSEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CTQPRRVAAMSVAARVAREMGVKLGNEVGYSIRFEDCTSERTVLRYMTDGMLLREFLSEP
              160       170       180       190       200       210

     510       520       530       540       550       560         
pF1KA0 DLASYSVVMVDEAHERTLHTDILFGLIKDVARFRPELKVLVASATMDTARFSTFFDDAPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLASYSVVMVDEAHERTLHTDILFGLIKDVARFRPELKVLVASATMDTARFSTFFDDAPV
              220       230       240       250       260       270

     570       580       590       600       610       620         
pF1KA0 FRIPGRRFPVDIFYTKAPEADYLEACVVSVLQIHVTQPPGDILVFLTGQEEIEAACEMLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FRIPGRRFPVDIFYTKAPEADYLEACVVSVLQIHVTQPPGDILVFLTGQEEIEAACEMLQ
              280       290       300       310       320       330

     630       640       650       660       670       680         
pF1KA0 DRCRRLGSKIRELLVLPIYANLPSDMQARIFQPTPPGARKVVVATNIAETSLTIEGIIYV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DRCRRLGSKIRELLVLPIYANLPSDMQARIFQPTPPGARKVVVATNIAETSLTIEGIIYV
              340       350       360       370       380       390

     690       700       710       720       730       740         
pF1KA0 LDPGFCKQKSYNPRTGMESLTVTPCSKASANQRAGRAGRVAAGKCFRLYTAWAYQHELEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDPGFCKQKSYNPRTGMESLTVTPCSKASANQRAGRAGRVAAGKCFRLYTAWAYQHELEE
              400       410       420       430       440       450

     750       760       770       780       790       800         
pF1KA0 TTVPEIQRTSLGNVVLLLKSLGIHDLMHFDFLDPPPYETLLLALEQLYALGALNHLGELT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TTVPEIQRTSLGNVVLLLKSLGIHDLMHFDFLDPPPYETLLLALEQLYALGALNHLGELT
              460       470       480       490       500       510

     810       820       830       840       850       860         
pF1KA0 TSGRKMAELPVDPMLSKMILASEKYSCSEEILTVAAMLSVNNSIFYRPKDKVVHADNARV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSGRKMAELPVDPMLSKMILASEKYSCSEEILTVAAMLSVNNSIFYRPKDKVVHADNARV
              520       530       540       550       560       570

     870       880       890       900       910       920         
pF1KA0 NFFLPGGDHLVLLNVYTQWAESGYSSQWCYENFVQFRSMRRARDVREQLEGLLERVEVGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NFFLPGGDHLVLLNVYTQWAESGYSSQWCYENFVQFRSMRRARDVREQLEGLLERVEVGL
              580       590       600       610       620       630

     930       940       950       960       970       980         
pF1KA0 SSCQGDYIRVRKAITAGYFYHTARLTRSGYRTVKQQQTVFIHPNSSLFEQQPRWLLYHEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSCQGDYIRVRKAITAGYFYHTARLTRSGYRTVKQQQTVFIHPNSSLFEQQPRWLLYHEL
              640       650       660       670       680       690

     990      1000      1010      1020      1030      1040 
pF1KA0 VLTTKEFMRQVLEIESSWLLEVAPHYYKAKELEDPHAKKMPKKIGKTREELG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLTTKEFMRQVLEIESSWLLEVAPHYYKAKELEDPHAKKMPKKIGKTREELG
              700       710       720       730       740  

>>XP_011513242 (OMIM: 603405) PREDICTED: putative pre-mR  (560 aa)
 initn: 3474 init1: 3474 opt: 3474  Z-score: 1773.8  bits: 339.0 E(85289): 4.6e-92
Smith-Waterman score: 3474; 100.0% identity (100.0% similar) in 526 aa overlap (516-1041:35-560)

         490       500       510       520       530       540     
pF1KA0 CTSERTVLRYMTDGMLLREFLSEPDLASYSVVMVDEAHERTLHTDILFGLIKDVARFRPE
                                     ::::::::::::::::::::::::::::::
XP_011 PAQECLMQMFLPIEPACFVEWLGTSPSQLGVVMVDEAHERTLHTDILFGLIKDVARFRPE
           10        20        30        40        50        60    

         550       560       570       580       590       600     
pF1KA0 LKVLVASATMDTARFSTFFDDAPVFRIPGRRFPVDIFYTKAPEADYLEACVVSVLQIHVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKVLVASATMDTARFSTFFDDAPVFRIPGRRFPVDIFYTKAPEADYLEACVVSVLQIHVT
           70        80        90       100       110       120    

         610       620       630       640       650       660     
pF1KA0 QPPGDILVFLTGQEEIEAACEMLQDRCRRLGSKIRELLVLPIYANLPSDMQARIFQPTPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QPPGDILVFLTGQEEIEAACEMLQDRCRRLGSKIRELLVLPIYANLPSDMQARIFQPTPP
          130       140       150       160       170       180    

         670       680       690       700       710       720     
pF1KA0 GARKVVVATNIAETSLTIEGIIYVLDPGFCKQKSYNPRTGMESLTVTPCSKASANQRAGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GARKVVVATNIAETSLTIEGIIYVLDPGFCKQKSYNPRTGMESLTVTPCSKASANQRAGR
          190       200       210       220       230       240    

         730       740       750       760       770       780     
pF1KA0 AGRVAAGKCFRLYTAWAYQHELEETTVPEIQRTSLGNVVLLLKSLGIHDLMHFDFLDPPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGRVAAGKCFRLYTAWAYQHELEETTVPEIQRTSLGNVVLLLKSLGIHDLMHFDFLDPPP
          250       260       270       280       290       300    

         790       800       810       820       830       840     
pF1KA0 YETLLLALEQLYALGALNHLGELTTSGRKMAELPVDPMLSKMILASEKYSCSEEILTVAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YETLLLALEQLYALGALNHLGELTTSGRKMAELPVDPMLSKMILASEKYSCSEEILTVAA
          310       320       330       340       350       360    

         850       860       870       880       890       900     
pF1KA0 MLSVNNSIFYRPKDKVVHADNARVNFFLPGGDHLVLLNVYTQWAESGYSSQWCYENFVQF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLSVNNSIFYRPKDKVVHADNARVNFFLPGGDHLVLLNVYTQWAESGYSSQWCYENFVQF
          370       380       390       400       410       420    

         910       920       930       940       950       960     
pF1KA0 RSMRRARDVREQLEGLLERVEVGLSSCQGDYIRVRKAITAGYFYHTARLTRSGYRTVKQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSMRRARDVREQLEGLLERVEVGLSSCQGDYIRVRKAITAGYFYHTARLTRSGYRTVKQQ
          430       440       450       460       470       480    

         970       980       990      1000      1010      1020     
pF1KA0 QTVFIHPNSSLFEQQPRWLLYHELVLTTKEFMRQVLEIESSWLLEVAPHYYKAKELEDPH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QTVFIHPNSSLFEQQPRWLLYHELVLTTKEFMRQVLEIESSWLLEVAPHYYKAKELEDPH
          490       500       510       520       530       540    

        1030      1040 
pF1KA0 AKKMPKKIGKTREELG
       ::::::::::::::::
XP_011 AKKMPKKIGKTREELG
          550       560

>>XP_011513243 (OMIM: 603405) PREDICTED: putative pre-mR  (524 aa)
 initn: 3464 init1: 3464 opt: 3464  Z-score: 1769.2  bits: 338.0 E(85289): 8.3e-92
Smith-Waterman score: 3464; 100.0% identity (100.0% similar) in 524 aa overlap (518-1041:1-524)

       490       500       510       520       530       540       
pF1KA0 SERTVLRYMTDGMLLREFLSEPDLASYSVVMVDEAHERTLHTDILFGLIKDVARFRPELK
                                     ::::::::::::::::::::::::::::::
XP_011                               MVDEAHERTLHTDILFGLIKDVARFRPELK
                                             10        20        30

       550       560       570       580       590       600       
pF1KA0 VLVASATMDTARFSTFFDDAPVFRIPGRRFPVDIFYTKAPEADYLEACVVSVLQIHVTQP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLVASATMDTARFSTFFDDAPVFRIPGRRFPVDIFYTKAPEADYLEACVVSVLQIHVTQP
               40        50        60        70        80        90

       610       620       630       640       650       660       
pF1KA0 PGDILVFLTGQEEIEAACEMLQDRCRRLGSKIRELLVLPIYANLPSDMQARIFQPTPPGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGDILVFLTGQEEIEAACEMLQDRCRRLGSKIRELLVLPIYANLPSDMQARIFQPTPPGA
              100       110       120       130       140       150

       670       680       690       700       710       720       
pF1KA0 RKVVVATNIAETSLTIEGIIYVLDPGFCKQKSYNPRTGMESLTVTPCSKASANQRAGRAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKVVVATNIAETSLTIEGIIYVLDPGFCKQKSYNPRTGMESLTVTPCSKASANQRAGRAG
              160       170       180       190       200       210

       730       740       750       760       770       780       
pF1KA0 RVAAGKCFRLYTAWAYQHELEETTVPEIQRTSLGNVVLLLKSLGIHDLMHFDFLDPPPYE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVAAGKCFRLYTAWAYQHELEETTVPEIQRTSLGNVVLLLKSLGIHDLMHFDFLDPPPYE
              220       230       240       250       260       270

       790       800       810       820       830       840       
pF1KA0 TLLLALEQLYALGALNHLGELTTSGRKMAELPVDPMLSKMILASEKYSCSEEILTVAAML
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLLLALEQLYALGALNHLGELTTSGRKMAELPVDPMLSKMILASEKYSCSEEILTVAAML
              280       290       300       310       320       330

       850       860       870       880       890       900       
pF1KA0 SVNNSIFYRPKDKVVHADNARVNFFLPGGDHLVLLNVYTQWAESGYSSQWCYENFVQFRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVNNSIFYRPKDKVVHADNARVNFFLPGGDHLVLLNVYTQWAESGYSSQWCYENFVQFRS
              340       350       360       370       380       390

       910       920       930       940       950       960       
pF1KA0 MRRARDVREQLEGLLERVEVGLSSCQGDYIRVRKAITAGYFYHTARLTRSGYRTVKQQQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRRARDVREQLEGLLERVEVGLSSCQGDYIRVRKAITAGYFYHTARLTRSGYRTVKQQQT
              400       410       420       430       440       450

       970       980       990      1000      1010      1020       
pF1KA0 VFIHPNSSLFEQQPRWLLYHELVLTTKEFMRQVLEIESSWLLEVAPHYYKAKELEDPHAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VFIHPNSSLFEQQPRWLLYHELVLTTKEFMRQVLEIESSWLLEVAPHYYKAKELEDPHAK
              460       470       480       490       500       510

      1030      1040 
pF1KA0 KMPKKIGKTREELG
       ::::::::::::::
XP_011 KMPKKIGKTREELG
              520    

>>NP_001309145 (OMIM: 600396) ATP-dependent RNA helicase  (945 aa)
 initn: 2591 init1: 1960 opt: 2590  Z-score: 1326.3  bits: 256.9 E(85289): 3.9e-67
Smith-Waterman score: 2604; 48.7% identity (75.0% similar) in 855 aa overlap (189-1039:108-924)

      160       170       180       190        200       210       
pF1KA0 ESEDEWERTERERLQDLEERDAFAERVRQRDKDRTRNVLER-SDKKAYEEAQKRLKMAEE
                                     : .  :. : : :: . .:   :..  :. 
NP_001 NLVGETNEETSMRNPDRPTHLSLVSAPEVEDDSLERKRLTRISDPEKWE--IKQMIAANV
        80        90       100       110       120         130     

       220       230       240       250       260       270       
pF1KA0 DRKAMVPELRKKSRREYLAKREREKLEDLEAELADEEFLFGDVELSRHERQELKYK--RR
         :   :.. ...    : : . :. :::: ::..::  :    :  : .: . ..  . 
NP_001 LSKEEFPDFDEET--GILPKVDDEEDEDLEIELVEEEPPF----LRGHTKQSMDMSPIKI
         140         150       160       170           180         

         280       290       300       310       320       330     
pF1KA0 VRDLAREYRAAGEQEKLEATNRYHMPKETRGQPARAVDLVEEESGAPGEEQRRWEEARLG
       :..       :. ...  : .: .. .  :           : .. :   ...: .    
NP_001 VKNPDGSLSQAAMMQSALAKERRELKQAQREA---------EMDSIPMGLNKHWVDPLPD
     190       200       210       220                230       240

         340       350       360       370       380       390     
pF1KA0 AASLKFGARDAASQEPKYQLVLEEEETIEFVRATQLQGDEEPSAPPTSTQAQQKESIQAV
       :     : . ::...   ..     . :   .   . :..      .:   . . ::   
NP_001 AE----GRQIAANMRGIGMM----PNDIPEWKKHAFGGNK------ASYGKKTQMSILEQ
                  250           260       270             280      

         400       410       420       430       440       450     
pF1KA0 RRSLPVFPFREELLAAIANHQVLIIEGETGSGKTTQIPQYLFEEGYTNKGMKIACTQPRR
       :.:::.. ..:.:. :. ..:.::. ::::::::::: ::: : :::..: ::.::::::
NP_001 RESLPIYKLKEQLVQAVHDNQILIVIGETGSGKTTQITQYLAEAGYTSRG-KIGCTQPRR
        290       300       310       320       330        340     

         460       470       480       490       500       510     
pF1KA0 VAAMSVAARVAREMGVKLGNEVGYSIRFEDCTSERTVLRYMTDGMLLREFLSEPDLASYS
       ::::::: ::..:.:  ::.::::.:::::::: .::..:::::::::: : .:::..:.
NP_001 VAAMSVAKRVSEEFGCCLGQEVGYTIRFEDCTSPETVIKYMTDGMLLRECLIDPDLTQYA
         350       360       370       380       390       400     

         520       530       540       550       560       570     
pF1KA0 VVMVDEAHERTLHTDILFGLIKDVARFRPELKVLVASATMDTARFSTFFDDAPVFRIPGR
       ..:.:::::::.:::.::::.: ... : ..:..:.:::.:...:: .: .::.: ::::
NP_001 IIMLDEAHERTIHTDVLFGLLKKTVQKRQDMKLIVTSATLDAVKFSQYFYEAPIFTIPGR
         410       420       430       440       450       460     

         580       590       600       610       620       630     
pF1KA0 RFPVDIFYTKAPEADYLEACVVSVLQIHVTQPPGDILVFLTGQEEIEAACEMLQDRCRRL
        .::.:.::: ::.:::.: ...:.:::.:.:::::::::::::::..:::.: .: . :
NP_001 TYPVEILYTKEPETDYLDASLITVMQIHLTEPPGDILVFLTGQEEIDTACEILYERMKSL
         470       480       490       500       510       520     

         640       650       660       670       680       690     
pF1KA0 GSKIRELLVLPIYANLPSDMQARIFQPTPPGARKVVVATNIAETSLTIEGIIYVLDPGFC
       :  . ::..::.:. :::.::.:::.:.:::.::::.:::::::::::.:: ::.:::: 
NP_001 GPDVPELIILPVYSALPSEMQTRIFDPAPPGSRKVVIATNIAETSLTIDGIYYVVDPGFV
         530       540       550       560       570       580     

         700       710       720       730       740       750     
pF1KA0 KQKSYNPRTGMESLTVTPCSKASANQRAGRAGRVAAGKCFRLYTAWAYQHELEETTVPEI
       ::: :: .::...:.::: :.:.:.::::::::.. :::.::::  ::. :.  :.::::
NP_001 KQKVYNSKTGIDQLVVTPISQAQAKQRAGRAGRTGPGKCYRLYTERAYRDEMLTTNVPEI
         590       600       610       620       630       640     

         760       770       780       790       800       810     
pF1KA0 QRTSLGNVVLLLKSLGIHDLMHFDFLDPPPYETLLLALEQLYALGALNHLGELTTSGRKM
       :::.:...:: ::..::.::. :::.: ::.:::. :.::::.::::.  : ::  ::.:
NP_001 QRTNLASTVLSLKAMGINDLLSFDFMDAPPMETLITAMEQLYTLGALDDEGLLTRLGRRM
         650       660       670       680       690       700     

         820       830       840       850       860       870     
pF1KA0 AELPVDPMLSKMILASEKYSCSEEILTVAAMLSVNNSIFYRPKDKVVHADNARVNFFLPG
       ::.:..::: ::.. : . .::::.::...::::.: .::::::: . ::. ...:    
NP_001 AEFPLEPMLCKMLIMSVHLGCSEEMLTIVSMLSVQN-VFYRPKDKQALADQKKAKFHQTE
         710       720       730       740        750       760    

         880       890       900       910       920       930     
pF1KA0 GDHLVLLNVYTQWAESGYSSQWCYENFVQFRSMRRARDVREQLEGLLERVEVGLSSCQGD
       ::::.:: ::..: .. .:. ::::::.: ::.:::.:.:.:. :...: .. . ::  .
NP_001 GDHLTLLAVYNSWKNNKFSNPWCYENFIQARSLRRAQDIRKQMLGIMDRHKLDVVSCGKS
          770       780       790       800       810       820    

         940       950        960       970       980       990    
pF1KA0 YIRVRKAITAGYFYHTARLT-RSGYRTVKQQQTVFIHPNSSLFEQQPRWLLYHELVLTTK
        .::.::: .:.: ..:.   . ::::. .::.:.:::.:.::..::.:..:::::::::
NP_001 TVRVQKAICSGFFRNAAKKDPQEGYRTLIDQQVVYIHPSSALFNRQPEWVVYHELVLTTK
          830       840       850       860       870       880    

         1000      1010      1020      1030      1040              
pF1KA0 EFMRQVLEIESSWLLEVAPHYYKAKELEDPHAKKMPKKIGKTREELG             
       :.::.:  :.  ::.: :: ..:..   ::   :. :.  . : :               
NP_001 EYMREVTTIDPRWLVEFAPAFFKVS---DP--TKLSKQKKQQRLEPLYNRYEEPNAWRIS
          890       900          910         920       930         

NP_001 RAFRRR
     940     

>>NP_001309146 (OMIM: 600396) ATP-dependent RNA helicase  (1129 aa)
 initn: 2652 init1: 1960 opt: 2590  Z-score: 1325.3  bits: 257.0 E(85289): 4.4e-67
Smith-Waterman score: 2604; 48.7% identity (75.0% similar) in 855 aa overlap (189-1039:292-1108)

      160       170       180       190        200       210       
pF1KA0 ESEDEWERTERERLQDLEERDAFAERVRQRDKDRTRNVLER-SDKKAYEEAQKRLKMAEE
                                     : .  :. : : :: . .:   :..  :. 
NP_001 NLVGETNEETSMRNPDRPTHLSLVSAPEVEDDSLERKRLTRISDPEKWE--IKQMIAANV
             270       280       290       300       310           

       220       230       240       250       260       270       
pF1KA0 DRKAMVPELRKKSRREYLAKREREKLEDLEAELADEEFLFGDVELSRHERQELKYK--RR
         :   :.. ...    : : . :. :::: ::..::  :    :  : .: . ..  . 
NP_001 LSKEEFPDFDEET--GILPKVDDEEDEDLEIELVEEEPPF----LRGHTKQSMDMSPIKI
     320       330         340       350           360       370   

         280       290       300       310       320       330     
pF1KA0 VRDLAREYRAAGEQEKLEATNRYHMPKETRGQPARAVDLVEEESGAPGEEQRRWEEARLG
       :..       :. ...  : .: .. .  :           : .. :   ...: .    
NP_001 VKNPDGSLSQAAMMQSALAKERRELKQAQREA---------EMDSIPMGLNKHWVDPLPD
           380       390       400                410       420    

         340       350       360       370       380       390     
pF1KA0 AASLKFGARDAASQEPKYQLVLEEEETIEFVRATQLQGDEEPSAPPTSTQAQQKESIQAV
       :     : . ::...   ..     . :   .   . :..      .:   . . ::   
NP_001 AE----GRQIAANMRGIGMM----PNDIPEWKKHAFGGNK------ASYGKKTQMSILEQ
              430       440           450             460       470

         400       410       420       430       440       450     
pF1KA0 RRSLPVFPFREELLAAIANHQVLIIEGETGSGKTTQIPQYLFEEGYTNKGMKIACTQPRR
       :.:::.. ..:.:. :. ..:.::. ::::::::::: ::: : :::..: ::.::::::
NP_001 RESLPIYKLKEQLVQAVHDNQILIVIGETGSGKTTQITQYLAEAGYTSRG-KIGCTQPRR
              480       490       500       510       520          

         460       470       480       490       500       510     
pF1KA0 VAAMSVAARVAREMGVKLGNEVGYSIRFEDCTSERTVLRYMTDGMLLREFLSEPDLASYS
       ::::::: ::..:.:  ::.::::.:::::::: .::..:::::::::: : .:::..:.
NP_001 VAAMSVAKRVSEEFGCCLGQEVGYTIRFEDCTSPETVIKYMTDGMLLRECLIDPDLTQYA
     530       540       550       560       570       580         

         520       530       540       550       560       570     
pF1KA0 VVMVDEAHERTLHTDILFGLIKDVARFRPELKVLVASATMDTARFSTFFDDAPVFRIPGR
       ..:.:::::::.:::.::::.: ... : ..:..:.:::.:...:: .: .::.: ::::
NP_001 IIMLDEAHERTIHTDVLFGLLKKTVQKRQDMKLIVTSATLDAVKFSQYFYEAPIFTIPGR
     590       600       610       620       630       640         

         580       590       600       610       620       630     
pF1KA0 RFPVDIFYTKAPEADYLEACVVSVLQIHVTQPPGDILVFLTGQEEIEAACEMLQDRCRRL
        .::.:.::: ::.:::.: ...:.:::.:.:::::::::::::::..:::.: .: . :
NP_001 TYPVEILYTKEPETDYLDASLITVMQIHLTEPPGDILVFLTGQEEIDTACEILYERMKSL
     650       660       670       680       690       700         

         640       650       660       670       680       690     
pF1KA0 GSKIRELLVLPIYANLPSDMQARIFQPTPPGARKVVVATNIAETSLTIEGIIYVLDPGFC
       :  . ::..::.:. :::.::.:::.:.:::.::::.:::::::::::.:: ::.:::: 
NP_001 GPDVPELIILPVYSALPSEMQTRIFDPAPPGSRKVVIATNIAETSLTIDGIYYVVDPGFV
     710       720       730       740       750       760         

         700       710       720       730       740       750     
pF1KA0 KQKSYNPRTGMESLTVTPCSKASANQRAGRAGRVAAGKCFRLYTAWAYQHELEETTVPEI
       ::: :: .::...:.::: :.:.:.::::::::.. :::.::::  ::. :.  :.::::
NP_001 KQKVYNSKTGIDQLVVTPISQAQAKQRAGRAGRTGPGKCYRLYTERAYRDEMLTTNVPEI
     770       780       790       800       810       820         

         760       770       780       790       800       810     
pF1KA0 QRTSLGNVVLLLKSLGIHDLMHFDFLDPPPYETLLLALEQLYALGALNHLGELTTSGRKM
       :::.:...:: ::..::.::. :::.: ::.:::. :.::::.::::.  : ::  ::.:
NP_001 QRTNLASTVLSLKAMGINDLLSFDFMDAPPMETLITAMEQLYTLGALDDEGLLTRLGRRM
     830       840       850       860       870       880         

         820       830       840       850       860       870     
pF1KA0 AELPVDPMLSKMILASEKYSCSEEILTVAAMLSVNNSIFYRPKDKVVHADNARVNFFLPG
       ::.:..::: ::.. : . .::::.::...::::.: .::::::: . ::. ...:    
NP_001 AEFPLEPMLCKMLIMSVHLGCSEEMLTIVSMLSVQN-VFYRPKDKQALADQKKAKFHQTE
     890       900       910       920        930       940        

         880       890       900       910       920       930     
pF1KA0 GDHLVLLNVYTQWAESGYSSQWCYENFVQFRSMRRARDVREQLEGLLERVEVGLSSCQGD
       ::::.:: ::..: .. .:. ::::::.: ::.:::.:.:.:. :...: .. . ::  .
NP_001 GDHLTLLAVYNSWKNNKFSNPWCYENFIQARSLRRAQDIRKQMLGIMDRHKLDVVSCGKS
      950       960       970       980       990      1000        

         940       950        960       970       980       990    
pF1KA0 YIRVRKAITAGYFYHTARLT-RSGYRTVKQQQTVFIHPNSSLFEQQPRWLLYHELVLTTK
        .::.::: .:.: ..:.   . ::::. .::.:.:::.:.::..::.:..:::::::::
NP_001 TVRVQKAICSGFFRNAAKKDPQEGYRTLIDQQVVYIHPSSALFNRQPEWVVYHELVLTTK
     1010      1020      1030      1040      1050      1060        

         1000      1010      1020      1030      1040              
pF1KA0 EFMRQVLEIESSWLLEVAPHYYKAKELEDPHAKKMPKKIGKTREELG             
       :.::.:  :.  ::.: :: ..:..   ::   :. :.  . : :               
NP_001 EYMREVTTIDPRWLVEFAPAFFKVS---DP--TKLSKQKKQQRLEPLYNRYEEPNAWRIS
     1070      1080      1090           1100      1110      1120   

NP_001 RAFRRR
             

>>NP_001309150 (OMIM: 600396) ATP-dependent RNA helicase  (1218 aa)
 initn: 2652 init1: 1960 opt: 2590  Z-score: 1324.9  bits: 257.0 E(85289): 4.7e-67
Smith-Waterman score: 2604; 48.7% identity (75.0% similar) in 855 aa overlap (189-1039:381-1197)

      160       170       180       190        200       210       
pF1KA0 ESEDEWERTERERLQDLEERDAFAERVRQRDKDRTRNVLER-SDKKAYEEAQKRLKMAEE
                                     : .  :. : : :: . .:   :..  :. 
NP_001 NLVGETNEETSMRNPDRPTHLSLVSAPEVEDDSLERKRLTRISDPEKWE--IKQMIAANV
              360       370       380       390         400        

       220       230       240       250       260       270       
pF1KA0 DRKAMVPELRKKSRREYLAKREREKLEDLEAELADEEFLFGDVELSRHERQELKYK--RR
         :   :.. ...    : : . :. :::: ::..::  :    :  : .: . ..  . 
NP_001 LSKEEFPDFDEET--GILPKVDDEEDEDLEIELVEEEPPF----LRGHTKQSMDMSPIKI
      410       420         430       440           450       460  

         280       290       300       310       320       330     
pF1KA0 VRDLAREYRAAGEQEKLEATNRYHMPKETRGQPARAVDLVEEESGAPGEEQRRWEEARLG
       :..       :. ...  : .: .. .  :           : .. :   ...: .    
NP_001 VKNPDGSLSQAAMMQSALAKERRELKQAQREA---------EMDSIPMGLNKHWVDPLPD
            470       480       490                500       510   

         340       350       360       370       380       390     
pF1KA0 AASLKFGARDAASQEPKYQLVLEEEETIEFVRATQLQGDEEPSAPPTSTQAQQKESIQAV
       :     : . ::...   ..     . :   .   . :..      .:   . . ::   
NP_001 AE----GRQIAANMRGIGMM----PNDIPEWKKHAFGGNK------ASYGKKTQMSILEQ
               520           530       540             550         

         400       410       420       430       440       450     
pF1KA0 RRSLPVFPFREELLAAIANHQVLIIEGETGSGKTTQIPQYLFEEGYTNKGMKIACTQPRR
       :.:::.. ..:.:. :. ..:.::. ::::::::::: ::: : :::..: ::.::::::
NP_001 RESLPIYKLKEQLVQAVHDNQILIVIGETGSGKTTQITQYLAEAGYTSRG-KIGCTQPRR
     560       570       580       590       600        610        

         460       470       480       490       500       510     
pF1KA0 VAAMSVAARVAREMGVKLGNEVGYSIRFEDCTSERTVLRYMTDGMLLREFLSEPDLASYS
       ::::::: ::..:.:  ::.::::.:::::::: .::..:::::::::: : .:::..:.
NP_001 VAAMSVAKRVSEEFGCCLGQEVGYTIRFEDCTSPETVIKYMTDGMLLRECLIDPDLTQYA
      620       630       640       650       660       670        

         520       530       540       550       560       570     
pF1KA0 VVMVDEAHERTLHTDILFGLIKDVARFRPELKVLVASATMDTARFSTFFDDAPVFRIPGR
       ..:.:::::::.:::.::::.: ... : ..:..:.:::.:...:: .: .::.: ::::
NP_001 IIMLDEAHERTIHTDVLFGLLKKTVQKRQDMKLIVTSATLDAVKFSQYFYEAPIFTIPGR
      680       690       700       710       720       730        

         580       590       600       610       620       630     
pF1KA0 RFPVDIFYTKAPEADYLEACVVSVLQIHVTQPPGDILVFLTGQEEIEAACEMLQDRCRRL
        .::.:.::: ::.:::.: ...:.:::.:.:::::::::::::::..:::.: .: . :
NP_001 TYPVEILYTKEPETDYLDASLITVMQIHLTEPPGDILVFLTGQEEIDTACEILYERMKSL
      740       750       760       770       780       790        

         640       650       660       670       680       690     
pF1KA0 GSKIRELLVLPIYANLPSDMQARIFQPTPPGARKVVVATNIAETSLTIEGIIYVLDPGFC
       :  . ::..::.:. :::.::.:::.:.:::.::::.:::::::::::.:: ::.:::: 
NP_001 GPDVPELIILPVYSALPSEMQTRIFDPAPPGSRKVVIATNIAETSLTIDGIYYVVDPGFV
      800       810       820       830       840       850        

         700       710       720       730       740       750     
pF1KA0 KQKSYNPRTGMESLTVTPCSKASANQRAGRAGRVAAGKCFRLYTAWAYQHELEETTVPEI
       ::: :: .::...:.::: :.:.:.::::::::.. :::.::::  ::. :.  :.::::
NP_001 KQKVYNSKTGIDQLVVTPISQAQAKQRAGRAGRTGPGKCYRLYTERAYRDEMLTTNVPEI
      860       870       880       890       900       910        

         760       770       780       790       800       810     
pF1KA0 QRTSLGNVVLLLKSLGIHDLMHFDFLDPPPYETLLLALEQLYALGALNHLGELTTSGRKM
       :::.:...:: ::..::.::. :::.: ::.:::. :.::::.::::.  : ::  ::.:
NP_001 QRTNLASTVLSLKAMGINDLLSFDFMDAPPMETLITAMEQLYTLGALDDEGLLTRLGRRM
      920       930       940       950       960       970        

         820       830       840       850       860       870     
pF1KA0 AELPVDPMLSKMILASEKYSCSEEILTVAAMLSVNNSIFYRPKDKVVHADNARVNFFLPG
       ::.:..::: ::.. : . .::::.::...::::.: .::::::: . ::. ...:    
NP_001 AEFPLEPMLCKMLIMSVHLGCSEEMLTIVSMLSVQN-VFYRPKDKQALADQKKAKFHQTE
      980       990      1000      1010       1020      1030       

         880       890       900       910       920       930     
pF1KA0 GDHLVLLNVYTQWAESGYSSQWCYENFVQFRSMRRARDVREQLEGLLERVEVGLSSCQGD
       ::::.:: ::..: .. .:. ::::::.: ::.:::.:.:.:. :...: .. . ::  .
NP_001 GDHLTLLAVYNSWKNNKFSNPWCYENFIQARSLRRAQDIRKQMLGIMDRHKLDVVSCGKS
      1040      1050      1060      1070      1080      1090       

         940       950        960       970       980       990    
pF1KA0 YIRVRKAITAGYFYHTARLT-RSGYRTVKQQQTVFIHPNSSLFEQQPRWLLYHELVLTTK
        .::.::: .:.: ..:.   . ::::. .::.:.:::.:.::..::.:..:::::::::
NP_001 TVRVQKAICSGFFRNAAKKDPQEGYRTLIDQQVVYIHPSSALFNRQPEWVVYHELVLTTK
      1100      1110      1120      1130      1140      1150       

         1000      1010      1020      1030      1040              
pF1KA0 EFMRQVLEIESSWLLEVAPHYYKAKELEDPHAKKMPKKIGKTREELG             
       :.::.:  :.  ::.: :: ..:..   ::   :. :.  . : :               
NP_001 EYMREVTTIDPRWLVEFAPAFFKVS---DP--TKLSKQKKQQRLEPLYNRYEEPNAWRIS
      1160      1170      1180           1190      1200      1210  

NP_001 RAFRRR
             

>>NP_004932 (OMIM: 600396) ATP-dependent RNA helicase DH  (1220 aa)
 initn: 2652 init1: 1960 opt: 2590  Z-score: 1324.9  bits: 257.0 E(85289): 4.7e-67
Smith-Waterman score: 2604; 48.7% identity (75.0% similar) in 855 aa overlap (189-1039:383-1199)

      160       170       180       190        200       210       
pF1KA0 ESEDEWERTERERLQDLEERDAFAERVRQRDKDRTRNVLER-SDKKAYEEAQKRLKMAEE
                                     : .  :. : : :: . .:   :..  :. 
NP_004 NLVGETNEETSMRNPDRPTHLSLVSAPEVEDDSLERKRLTRISDPEKWE--IKQMIAANV
            360       370       380       390       400         410

       220       230       240       250       260       270       
pF1KA0 DRKAMVPELRKKSRREYLAKREREKLEDLEAELADEEFLFGDVELSRHERQELKYK--RR
         :   :.. ...    : : . :. :::: ::..::  :    :  : .: . ..  . 
NP_004 LSKEEFPDFDEET--GILPKVDDEEDEDLEIELVEEEPPF----LRGHTKQSMDMSPIKI
              420         430       440           450       460    

         280       290       300       310       320       330     
pF1KA0 VRDLAREYRAAGEQEKLEATNRYHMPKETRGQPARAVDLVEEESGAPGEEQRRWEEARLG
       :..       :. ...  : .: .. .  :           : .. :   ...: .    
NP_004 VKNPDGSLSQAAMMQSALAKERRELKQAQREA---------EMDSIPMGLNKHWVDPLPD
          470       480       490                500       510     

         340       350       360       370       380       390     
pF1KA0 AASLKFGARDAASQEPKYQLVLEEEETIEFVRATQLQGDEEPSAPPTSTQAQQKESIQAV
       :     : . ::...   ..     . :   .   . :..      .:   . . ::   
NP_004 AE----GRQIAANMRGIGMM----PNDIPEWKKHAFGGNK------ASYGKKTQMSILEQ
             520       530           540             550       560 

         400       410       420       430       440       450     
pF1KA0 RRSLPVFPFREELLAAIANHQVLIIEGETGSGKTTQIPQYLFEEGYTNKGMKIACTQPRR
       :.:::.. ..:.:. :. ..:.::. ::::::::::: ::: : :::..: ::.::::::
NP_004 RESLPIYKLKEQLVQAVHDNQILIVIGETGSGKTTQITQYLAEAGYTSRG-KIGCTQPRR
             570       580       590       600       610        620

         460       470       480       490       500       510     
pF1KA0 VAAMSVAARVAREMGVKLGNEVGYSIRFEDCTSERTVLRYMTDGMLLREFLSEPDLASYS
       ::::::: ::..:.:  ::.::::.:::::::: .::..:::::::::: : .:::..:.
NP_004 VAAMSVAKRVSEEFGCCLGQEVGYTIRFEDCTSPETVIKYMTDGMLLRECLIDPDLTQYA
              630       640       650       660       670       680

         520       530       540       550       560       570     
pF1KA0 VVMVDEAHERTLHTDILFGLIKDVARFRPELKVLVASATMDTARFSTFFDDAPVFRIPGR
       ..:.:::::::.:::.::::.: ... : ..:..:.:::.:...:: .: .::.: ::::
NP_004 IIMLDEAHERTIHTDVLFGLLKKTVQKRQDMKLIVTSATLDAVKFSQYFYEAPIFTIPGR
              690       700       710       720       730       740

         580       590       600       610       620       630     
pF1KA0 RFPVDIFYTKAPEADYLEACVVSVLQIHVTQPPGDILVFLTGQEEIEAACEMLQDRCRRL
        .::.:.::: ::.:::.: ...:.:::.:.:::::::::::::::..:::.: .: . :
NP_004 TYPVEILYTKEPETDYLDASLITVMQIHLTEPPGDILVFLTGQEEIDTACEILYERMKSL
              750       760       770       780       790       800

         640       650       660       670       680       690     
pF1KA0 GSKIRELLVLPIYANLPSDMQARIFQPTPPGARKVVVATNIAETSLTIEGIIYVLDPGFC
       :  . ::..::.:. :::.::.:::.:.:::.::::.:::::::::::.:: ::.:::: 
NP_004 GPDVPELIILPVYSALPSEMQTRIFDPAPPGSRKVVIATNIAETSLTIDGIYYVVDPGFV
              810       820       830       840       850       860

         700       710       720       730       740       750     
pF1KA0 KQKSYNPRTGMESLTVTPCSKASANQRAGRAGRVAAGKCFRLYTAWAYQHELEETTVPEI
       ::: :: .::...:.::: :.:.:.::::::::.. :::.::::  ::. :.  :.::::
NP_004 KQKVYNSKTGIDQLVVTPISQAQAKQRAGRAGRTGPGKCYRLYTERAYRDEMLTTNVPEI
              870       880       890       900       910       920

         760       770       780       790       800       810     
pF1KA0 QRTSLGNVVLLLKSLGIHDLMHFDFLDPPPYETLLLALEQLYALGALNHLGELTTSGRKM
       :::.:...:: ::..::.::. :::.: ::.:::. :.::::.::::.  : ::  ::.:
NP_004 QRTNLASTVLSLKAMGINDLLSFDFMDAPPMETLITAMEQLYTLGALDDEGLLTRLGRRM
              930       940       950       960       970       980

         820       830       840       850       860       870     
pF1KA0 AELPVDPMLSKMILASEKYSCSEEILTVAAMLSVNNSIFYRPKDKVVHADNARVNFFLPG
       ::.:..::: ::.. : . .::::.::...::::.: .::::::: . ::. ...:    
NP_004 AEFPLEPMLCKMLIMSVHLGCSEEMLTIVSMLSVQN-VFYRPKDKQALADQKKAKFHQTE
              990      1000      1010       1020      1030         

         880       890       900       910       920       930     
pF1KA0 GDHLVLLNVYTQWAESGYSSQWCYENFVQFRSMRRARDVREQLEGLLERVEVGLSSCQGD
       ::::.:: ::..: .. .:. ::::::.: ::.:::.:.:.:. :...: .. . ::  .
NP_004 GDHLTLLAVYNSWKNNKFSNPWCYENFIQARSLRRAQDIRKQMLGIMDRHKLDVVSCGKS
    1040      1050      1060      1070      1080      1090         

         940       950        960       970       980       990    
pF1KA0 YIRVRKAITAGYFYHTARLT-RSGYRTVKQQQTVFIHPNSSLFEQQPRWLLYHELVLTTK
        .::.::: .:.: ..:.   . ::::. .::.:.:::.:.::..::.:..:::::::::
NP_004 TVRVQKAICSGFFRNAAKKDPQEGYRTLIDQQVVYIHPSSALFNRQPEWVVYHELVLTTK
    1100      1110      1120      1130      1140      1150         

         1000      1010      1020      1030      1040              
pF1KA0 EFMRQVLEIESSWLLEVAPHYYKAKELEDPHAKKMPKKIGKTREELG             
       :.::.:  :.  ::.: :: ..:..   ::   :. :.  . : :               
NP_004 EYMREVTTIDPRWLVEFAPAFFKVS---DP--TKLSKQKKQQRLEPLYNRYEEPNAWRIS
    1160      1170      1180           1190      1200      1210    

NP_004 RAFRRR
         1220




1041 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 09:45:19 2016 done: Thu Nov  3 09:45:22 2016
 Total Scan time: 16.600 Total Display time:  0.370

Function used was FASTA [36.3.4 Apr, 2011]
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