Result of FASTA (omim) for pF1KSDB0040
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KSDB0040, 620 aa
  1>>>pF1KSDB0040 620 - 620 aa - 620 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 8.5776+/-0.000604; mu= 1.6073+/- 0.036
 mean_var=274.5967+/-58.582, 0's: 0 Z-trim(112.1): 427  B-trim: 355 in 2/55
 Lambda= 0.077397
 statistics sampled from 20382 (20938) to 20382 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.598), E-opt: 0.2 (0.245), width:  16
 Scan time:  8.140

The best scores are:                                      opt bits E(85289)
NP_116197 (OMIM: 609791) leucine-rich repeat and i ( 620) 4149 478.4 3.3e-134
NP_001288123 (OMIM: 609791) leucine-rich repeat an ( 614) 4112 474.2 5.7e-133
XP_016878171 (OMIM: 609791) PREDICTED: leucine-ric ( 614) 4112 474.2 5.7e-133
NP_001288128 (OMIM: 609791) leucine-rich repeat an ( 614) 4112 474.2 5.7e-133
NP_001288124 (OMIM: 609791) leucine-rich repeat an ( 614) 4112 474.2 5.7e-133
XP_011520420 (OMIM: 609791) PREDICTED: leucine-ric ( 614) 4112 474.2 5.7e-133
NP_001288129 (OMIM: 609791) leucine-rich repeat an ( 614) 4112 474.2 5.7e-133
NP_001288126 (OMIM: 609791) leucine-rich repeat an ( 614) 4112 474.2 5.7e-133
NP_001288115 (OMIM: 609791) leucine-rich repeat an ( 614) 4112 474.2 5.7e-133
NP_001288120 (OMIM: 609791) leucine-rich repeat an ( 614) 4112 474.2 5.7e-133
NP_001288127 (OMIM: 609791) leucine-rich repeat an ( 614) 4112 474.2 5.7e-133
NP_001288116 (OMIM: 609791) leucine-rich repeat an ( 614) 4112 474.2 5.7e-133
NP_001288121 (OMIM: 609791) leucine-rich repeat an ( 614) 4112 474.2 5.7e-133
NP_001288118 (OMIM: 609791) leucine-rich repeat an ( 614) 4112 474.2 5.7e-133
XP_011516021 (OMIM: 609793) PREDICTED: leucine-ric ( 606) 2519 296.3   2e-79
NP_001245211 (OMIM: 609793) leucine-rich repeat an ( 606) 2519 296.3   2e-79
XP_016869792 (OMIM: 609793) PREDICTED: leucine-ric ( 606) 2519 296.3   2e-79
XP_016869796 (OMIM: 609793) PREDICTED: leucine-ric ( 606) 2519 296.3   2e-79
XP_011516026 (OMIM: 609793) PREDICTED: leucine-ric ( 606) 2519 296.3   2e-79
NP_689783 (OMIM: 609793) leucine-rich repeat and i ( 606) 2519 296.3   2e-79
XP_011516030 (OMIM: 609793) PREDICTED: leucine-ric ( 606) 2519 296.3   2e-79
XP_016869795 (OMIM: 609793) PREDICTED: leucine-ric ( 606) 2519 296.3   2e-79
XP_016869794 (OMIM: 609793) PREDICTED: leucine-ric ( 606) 2519 296.3   2e-79
XP_016869793 (OMIM: 609793) PREDICTED: leucine-ric ( 606) 2519 296.3   2e-79
NP_001094861 (OMIM: 609792) leucine-rich repeat an ( 592) 1857 222.4 3.5e-57
NP_001004432 (OMIM: 609794) leucine-rich repeat an ( 593) 1491 181.5   7e-45
NP_060960 (OMIM: 606666,615311) leucine-rich repea ( 951)  533 74.8 1.5e-12
NP_001245348 (OMIM: 608817) leucine-rich repeat-co ( 640)  529 74.2 1.6e-12
XP_016873568 (OMIM: 608817) PREDICTED: leucine-ric ( 640)  529 74.2 1.6e-12
XP_011518542 (OMIM: 608817) PREDICTED: leucine-ric ( 640)  529 74.2 1.6e-12
XP_011518544 (OMIM: 608817) PREDICTED: leucine-ric ( 640)  529 74.2 1.6e-12
XP_016873567 (OMIM: 608817) PREDICTED: leucine-ric ( 640)  529 74.2 1.6e-12
XP_016873563 (OMIM: 608817) PREDICTED: leucine-ric ( 640)  529 74.2 1.6e-12
XP_011518540 (OMIM: 608817) PREDICTED: leucine-ric ( 640)  529 74.2 1.6e-12
XP_016873562 (OMIM: 608817) PREDICTED: leucine-ric ( 640)  529 74.2 1.6e-12
NP_065980 (OMIM: 608817) leucine-rich repeat-conta ( 640)  529 74.2 1.6e-12
XP_011518546 (OMIM: 608817) PREDICTED: leucine-ric ( 640)  529 74.2 1.6e-12
XP_016873566 (OMIM: 608817) PREDICTED: leucine-ric ( 640)  529 74.2 1.6e-12
XP_011518541 (OMIM: 608817) PREDICTED: leucine-ric ( 640)  529 74.2 1.6e-12
XP_011518545 (OMIM: 608817) PREDICTED: leucine-ric ( 640)  529 74.2 1.6e-12
XP_016873565 (OMIM: 608817) PREDICTED: leucine-ric ( 640)  529 74.2 1.6e-12
XP_016873559 (OMIM: 608817) PREDICTED: leucine-ric ( 640)  529 74.2 1.6e-12
XP_016873564 (OMIM: 608817) PREDICTED: leucine-ric ( 640)  529 74.2 1.6e-12
XP_016873561 (OMIM: 608817) PREDICTED: leucine-ric ( 640)  529 74.2 1.6e-12
XP_011518543 (OMIM: 608817) PREDICTED: leucine-ric ( 640)  529 74.2 1.6e-12
XP_016873560 (OMIM: 608817) PREDICTED: leucine-ric ( 640)  529 74.2 1.6e-12
NP_001278917 (OMIM: 603104) carboxypeptidase N sub ( 545)  522 73.3 2.5e-12
NP_001073982 (OMIM: 603104) carboxypeptidase N sub ( 545)  522 73.3 2.5e-12
XP_005269337 (OMIM: 603104) PREDICTED: carboxypept ( 545)  522 73.3 2.5e-12
XP_016874279 (OMIM: 608870) PREDICTED: leucine-ric ( 623)  520 73.1 3.2e-12


>>NP_116197 (OMIM: 609791) leucine-rich repeat and immun  (620 aa)
 initn: 4149 init1: 4149 opt: 4149  Z-score: 2530.5  bits: 478.4 E(85289): 3.3e-134
Smith-Waterman score: 4149; 100.0% identity (100.0% similar) in 620 aa overlap (1-620:1-620)

               10        20        30        40        50        60
pF1KSD MQVSKRMLAGGVRSMPSPLLACWQPILLLVLGSVLSGSATGCPPRCECSAQDRAVLCHRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 MQVSKRMLAGGVRSMPSPLLACWQPILLLVLGSVLSGSATGCPPRCECSAQDRAVLCHRK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD RFVAVPEGIPTETRLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 RFVAVPEGIPTETRLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD LRTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 LRTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD YISHRAFSGLNSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 YISHRAFSGLNSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD LKVLEISHWPYLDTMTPNCLYGLNLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 LKVLEISHWPYLDTMTPNCLYGLNLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPIS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD TIEGSMLHELLRLQEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 TIEGSMLHELLRLQEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGN
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD LETLILDSNPLACDCRLLWVFRRRWRLNFNRQQPTCATPEFVQGKEFKDFPDVLLPNYFT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 LETLILDSNPLACDCRLLWVFRRRWRLNFNRQQPTCATPEFVQGKEFKDFPDVLLPNYFT
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD CRRARIRDRKAQQVFVDEGHTVQFVCRADGDPPPAILWLSPRKHLVSAKSNGRLTVFPDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 CRRARIRDRKAQQVFVDEGHTVQFVCRADGDPPPAILWLSPRKHLVSAKSNGRLTVFPDG
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD TLEVRYAQVQDNGTYLCIAANAGGNDSMPAHLHVRSYSPDWPHQPNKTFAFISNQPGEGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 TLEVRYAQVQDNGTYLCIAANAGGNDSMPAHLHVRSYSPDWPHQPNKTFAFISNQPGEGE
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD ANSTRATVPFPFDIKTLIIATTMGFISFLGVVLFCLVLLFLWSRGKGNTKHNIEIEYVPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 ANSTRATVPFPFDIKTLIIATTMGFISFLGVVLFCLVLLFLWSRGKGNTKHNIEIEYVPR
              550       560       570       580       590       600

              610       620
pF1KSD KSDAGISSADAPRKFNMKMI
       ::::::::::::::::::::
NP_116 KSDAGISSADAPRKFNMKMI
              610       620

>>NP_001288123 (OMIM: 609791) leucine-rich repeat and im  (614 aa)
 initn: 4112 init1: 4112 opt: 4112  Z-score: 2508.2  bits: 474.2 E(85289): 5.7e-133
Smith-Waterman score: 4112; 100.0% identity (100.0% similar) in 614 aa overlap (7-620:1-614)

               10        20        30        40        50        60
pF1KSD MQVSKRMLAGGVRSMPSPLLACWQPILLLVLGSVLSGSATGCPPRCECSAQDRAVLCHRK
             ::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001       MLAGGVRSMPSPLLACWQPILLLVLGSVLSGSATGCPPRCECSAQDRAVLCHRK
                     10        20        30        40        50    

               70        80        90       100       110       120
pF1KSD RFVAVPEGIPTETRLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RFVAVPEGIPTETRLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFN
           60        70        80        90       100       110    

              130       140       150       160       170       180
pF1KSD LRTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLV
          120       130       140       150       160       170    

              190       200       210       220       230       240
pF1KSD YISHRAFSGLNSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YISHRAFSGLNSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYR
          180       190       200       210       220       230    

              250       260       270       280       290       300
pF1KSD LKVLEISHWPYLDTMTPNCLYGLNLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKVLEISHWPYLDTMTPNCLYGLNLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPIS
          240       250       260       270       280       290    

              310       320       330       340       350       360
pF1KSD TIEGSMLHELLRLQEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TIEGSMLHELLRLQEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGN
          300       310       320       330       340       350    

              370       380       390       400       410       420
pF1KSD LETLILDSNPLACDCRLLWVFRRRWRLNFNRQQPTCATPEFVQGKEFKDFPDVLLPNYFT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LETLILDSNPLACDCRLLWVFRRRWRLNFNRQQPTCATPEFVQGKEFKDFPDVLLPNYFT
          360       370       380       390       400       410    

              430       440       450       460       470       480
pF1KSD CRRARIRDRKAQQVFVDEGHTVQFVCRADGDPPPAILWLSPRKHLVSAKSNGRLTVFPDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CRRARIRDRKAQQVFVDEGHTVQFVCRADGDPPPAILWLSPRKHLVSAKSNGRLTVFPDG
          420       430       440       450       460       470    

              490       500       510       520       530       540
pF1KSD TLEVRYAQVQDNGTYLCIAANAGGNDSMPAHLHVRSYSPDWPHQPNKTFAFISNQPGEGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLEVRYAQVQDNGTYLCIAANAGGNDSMPAHLHVRSYSPDWPHQPNKTFAFISNQPGEGE
          480       490       500       510       520       530    

              550       560       570       580       590       600
pF1KSD ANSTRATVPFPFDIKTLIIATTMGFISFLGVVLFCLVLLFLWSRGKGNTKHNIEIEYVPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ANSTRATVPFPFDIKTLIIATTMGFISFLGVVLFCLVLLFLWSRGKGNTKHNIEIEYVPR
          540       550       560       570       580       590    

              610       620
pF1KSD KSDAGISSADAPRKFNMKMI
       ::::::::::::::::::::
NP_001 KSDAGISSADAPRKFNMKMI
          600       610    

>>XP_016878171 (OMIM: 609791) PREDICTED: leucine-rich re  (614 aa)
 initn: 4112 init1: 4112 opt: 4112  Z-score: 2508.2  bits: 474.2 E(85289): 5.7e-133
Smith-Waterman score: 4112; 100.0% identity (100.0% similar) in 614 aa overlap (7-620:1-614)

               10        20        30        40        50        60
pF1KSD MQVSKRMLAGGVRSMPSPLLACWQPILLLVLGSVLSGSATGCPPRCECSAQDRAVLCHRK
             ::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016       MLAGGVRSMPSPLLACWQPILLLVLGSVLSGSATGCPPRCECSAQDRAVLCHRK
                     10        20        30        40        50    

               70        80        90       100       110       120
pF1KSD RFVAVPEGIPTETRLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RFVAVPEGIPTETRLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFN
           60        70        80        90       100       110    

              130       140       150       160       170       180
pF1KSD LRTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLV
          120       130       140       150       160       170    

              190       200       210       220       230       240
pF1KSD YISHRAFSGLNSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YISHRAFSGLNSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYR
          180       190       200       210       220       230    

              250       260       270       280       290       300
pF1KSD LKVLEISHWPYLDTMTPNCLYGLNLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKVLEISHWPYLDTMTPNCLYGLNLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPIS
          240       250       260       270       280       290    

              310       320       330       340       350       360
pF1KSD TIEGSMLHELLRLQEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TIEGSMLHELLRLQEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGN
          300       310       320       330       340       350    

              370       380       390       400       410       420
pF1KSD LETLILDSNPLACDCRLLWVFRRRWRLNFNRQQPTCATPEFVQGKEFKDFPDVLLPNYFT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LETLILDSNPLACDCRLLWVFRRRWRLNFNRQQPTCATPEFVQGKEFKDFPDVLLPNYFT
          360       370       380       390       400       410    

              430       440       450       460       470       480
pF1KSD CRRARIRDRKAQQVFVDEGHTVQFVCRADGDPPPAILWLSPRKHLVSAKSNGRLTVFPDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CRRARIRDRKAQQVFVDEGHTVQFVCRADGDPPPAILWLSPRKHLVSAKSNGRLTVFPDG
          420       430       440       450       460       470    

              490       500       510       520       530       540
pF1KSD TLEVRYAQVQDNGTYLCIAANAGGNDSMPAHLHVRSYSPDWPHQPNKTFAFISNQPGEGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLEVRYAQVQDNGTYLCIAANAGGNDSMPAHLHVRSYSPDWPHQPNKTFAFISNQPGEGE
          480       490       500       510       520       530    

              550       560       570       580       590       600
pF1KSD ANSTRATVPFPFDIKTLIIATTMGFISFLGVVLFCLVLLFLWSRGKGNTKHNIEIEYVPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ANSTRATVPFPFDIKTLIIATTMGFISFLGVVLFCLVLLFLWSRGKGNTKHNIEIEYVPR
          540       550       560       570       580       590    

              610       620
pF1KSD KSDAGISSADAPRKFNMKMI
       ::::::::::::::::::::
XP_016 KSDAGISSADAPRKFNMKMI
          600       610    

>>NP_001288128 (OMIM: 609791) leucine-rich repeat and im  (614 aa)
 initn: 4112 init1: 4112 opt: 4112  Z-score: 2508.2  bits: 474.2 E(85289): 5.7e-133
Smith-Waterman score: 4112; 100.0% identity (100.0% similar) in 614 aa overlap (7-620:1-614)

               10        20        30        40        50        60
pF1KSD MQVSKRMLAGGVRSMPSPLLACWQPILLLVLGSVLSGSATGCPPRCECSAQDRAVLCHRK
             ::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001       MLAGGVRSMPSPLLACWQPILLLVLGSVLSGSATGCPPRCECSAQDRAVLCHRK
                     10        20        30        40        50    

               70        80        90       100       110       120
pF1KSD RFVAVPEGIPTETRLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RFVAVPEGIPTETRLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFN
           60        70        80        90       100       110    

              130       140       150       160       170       180
pF1KSD LRTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLV
          120       130       140       150       160       170    

              190       200       210       220       230       240
pF1KSD YISHRAFSGLNSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YISHRAFSGLNSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYR
          180       190       200       210       220       230    

              250       260       270       280       290       300
pF1KSD LKVLEISHWPYLDTMTPNCLYGLNLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKVLEISHWPYLDTMTPNCLYGLNLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPIS
          240       250       260       270       280       290    

              310       320       330       340       350       360
pF1KSD TIEGSMLHELLRLQEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TIEGSMLHELLRLQEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGN
          300       310       320       330       340       350    

              370       380       390       400       410       420
pF1KSD LETLILDSNPLACDCRLLWVFRRRWRLNFNRQQPTCATPEFVQGKEFKDFPDVLLPNYFT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LETLILDSNPLACDCRLLWVFRRRWRLNFNRQQPTCATPEFVQGKEFKDFPDVLLPNYFT
          360       370       380       390       400       410    

              430       440       450       460       470       480
pF1KSD CRRARIRDRKAQQVFVDEGHTVQFVCRADGDPPPAILWLSPRKHLVSAKSNGRLTVFPDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CRRARIRDRKAQQVFVDEGHTVQFVCRADGDPPPAILWLSPRKHLVSAKSNGRLTVFPDG
          420       430       440       450       460       470    

              490       500       510       520       530       540
pF1KSD TLEVRYAQVQDNGTYLCIAANAGGNDSMPAHLHVRSYSPDWPHQPNKTFAFISNQPGEGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLEVRYAQVQDNGTYLCIAANAGGNDSMPAHLHVRSYSPDWPHQPNKTFAFISNQPGEGE
          480       490       500       510       520       530    

              550       560       570       580       590       600
pF1KSD ANSTRATVPFPFDIKTLIIATTMGFISFLGVVLFCLVLLFLWSRGKGNTKHNIEIEYVPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ANSTRATVPFPFDIKTLIIATTMGFISFLGVVLFCLVLLFLWSRGKGNTKHNIEIEYVPR
          540       550       560       570       580       590    

              610       620
pF1KSD KSDAGISSADAPRKFNMKMI
       ::::::::::::::::::::
NP_001 KSDAGISSADAPRKFNMKMI
          600       610    

>>NP_001288124 (OMIM: 609791) leucine-rich repeat and im  (614 aa)
 initn: 4112 init1: 4112 opt: 4112  Z-score: 2508.2  bits: 474.2 E(85289): 5.7e-133
Smith-Waterman score: 4112; 100.0% identity (100.0% similar) in 614 aa overlap (7-620:1-614)

               10        20        30        40        50        60
pF1KSD MQVSKRMLAGGVRSMPSPLLACWQPILLLVLGSVLSGSATGCPPRCECSAQDRAVLCHRK
             ::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001       MLAGGVRSMPSPLLACWQPILLLVLGSVLSGSATGCPPRCECSAQDRAVLCHRK
                     10        20        30        40        50    

               70        80        90       100       110       120
pF1KSD RFVAVPEGIPTETRLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RFVAVPEGIPTETRLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFN
           60        70        80        90       100       110    

              130       140       150       160       170       180
pF1KSD LRTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLV
          120       130       140       150       160       170    

              190       200       210       220       230       240
pF1KSD YISHRAFSGLNSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YISHRAFSGLNSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYR
          180       190       200       210       220       230    

              250       260       270       280       290       300
pF1KSD LKVLEISHWPYLDTMTPNCLYGLNLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKVLEISHWPYLDTMTPNCLYGLNLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPIS
          240       250       260       270       280       290    

              310       320       330       340       350       360
pF1KSD TIEGSMLHELLRLQEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TIEGSMLHELLRLQEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGN
          300       310       320       330       340       350    

              370       380       390       400       410       420
pF1KSD LETLILDSNPLACDCRLLWVFRRRWRLNFNRQQPTCATPEFVQGKEFKDFPDVLLPNYFT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LETLILDSNPLACDCRLLWVFRRRWRLNFNRQQPTCATPEFVQGKEFKDFPDVLLPNYFT
          360       370       380       390       400       410    

              430       440       450       460       470       480
pF1KSD CRRARIRDRKAQQVFVDEGHTVQFVCRADGDPPPAILWLSPRKHLVSAKSNGRLTVFPDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CRRARIRDRKAQQVFVDEGHTVQFVCRADGDPPPAILWLSPRKHLVSAKSNGRLTVFPDG
          420       430       440       450       460       470    

              490       500       510       520       530       540
pF1KSD TLEVRYAQVQDNGTYLCIAANAGGNDSMPAHLHVRSYSPDWPHQPNKTFAFISNQPGEGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLEVRYAQVQDNGTYLCIAANAGGNDSMPAHLHVRSYSPDWPHQPNKTFAFISNQPGEGE
          480       490       500       510       520       530    

              550       560       570       580       590       600
pF1KSD ANSTRATVPFPFDIKTLIIATTMGFISFLGVVLFCLVLLFLWSRGKGNTKHNIEIEYVPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ANSTRATVPFPFDIKTLIIATTMGFISFLGVVLFCLVLLFLWSRGKGNTKHNIEIEYVPR
          540       550       560       570       580       590    

              610       620
pF1KSD KSDAGISSADAPRKFNMKMI
       ::::::::::::::::::::
NP_001 KSDAGISSADAPRKFNMKMI
          600       610    

>>XP_011520420 (OMIM: 609791) PREDICTED: leucine-rich re  (614 aa)
 initn: 4112 init1: 4112 opt: 4112  Z-score: 2508.2  bits: 474.2 E(85289): 5.7e-133
Smith-Waterman score: 4112; 100.0% identity (100.0% similar) in 614 aa overlap (7-620:1-614)

               10        20        30        40        50        60
pF1KSD MQVSKRMLAGGVRSMPSPLLACWQPILLLVLGSVLSGSATGCPPRCECSAQDRAVLCHRK
             ::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011       MLAGGVRSMPSPLLACWQPILLLVLGSVLSGSATGCPPRCECSAQDRAVLCHRK
                     10        20        30        40        50    

               70        80        90       100       110       120
pF1KSD RFVAVPEGIPTETRLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RFVAVPEGIPTETRLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFN
           60        70        80        90       100       110    

              130       140       150       160       170       180
pF1KSD LRTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLV
          120       130       140       150       160       170    

              190       200       210       220       230       240
pF1KSD YISHRAFSGLNSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YISHRAFSGLNSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYR
          180       190       200       210       220       230    

              250       260       270       280       290       300
pF1KSD LKVLEISHWPYLDTMTPNCLYGLNLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKVLEISHWPYLDTMTPNCLYGLNLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPIS
          240       250       260       270       280       290    

              310       320       330       340       350       360
pF1KSD TIEGSMLHELLRLQEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TIEGSMLHELLRLQEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGN
          300       310       320       330       340       350    

              370       380       390       400       410       420
pF1KSD LETLILDSNPLACDCRLLWVFRRRWRLNFNRQQPTCATPEFVQGKEFKDFPDVLLPNYFT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LETLILDSNPLACDCRLLWVFRRRWRLNFNRQQPTCATPEFVQGKEFKDFPDVLLPNYFT
          360       370       380       390       400       410    

              430       440       450       460       470       480
pF1KSD CRRARIRDRKAQQVFVDEGHTVQFVCRADGDPPPAILWLSPRKHLVSAKSNGRLTVFPDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CRRARIRDRKAQQVFVDEGHTVQFVCRADGDPPPAILWLSPRKHLVSAKSNGRLTVFPDG
          420       430       440       450       460       470    

              490       500       510       520       530       540
pF1KSD TLEVRYAQVQDNGTYLCIAANAGGNDSMPAHLHVRSYSPDWPHQPNKTFAFISNQPGEGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLEVRYAQVQDNGTYLCIAANAGGNDSMPAHLHVRSYSPDWPHQPNKTFAFISNQPGEGE
          480       490       500       510       520       530    

              550       560       570       580       590       600
pF1KSD ANSTRATVPFPFDIKTLIIATTMGFISFLGVVLFCLVLLFLWSRGKGNTKHNIEIEYVPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ANSTRATVPFPFDIKTLIIATTMGFISFLGVVLFCLVLLFLWSRGKGNTKHNIEIEYVPR
          540       550       560       570       580       590    

              610       620
pF1KSD KSDAGISSADAPRKFNMKMI
       ::::::::::::::::::::
XP_011 KSDAGISSADAPRKFNMKMI
          600       610    

>>NP_001288129 (OMIM: 609791) leucine-rich repeat and im  (614 aa)
 initn: 4112 init1: 4112 opt: 4112  Z-score: 2508.2  bits: 474.2 E(85289): 5.7e-133
Smith-Waterman score: 4112; 100.0% identity (100.0% similar) in 614 aa overlap (7-620:1-614)

               10        20        30        40        50        60
pF1KSD MQVSKRMLAGGVRSMPSPLLACWQPILLLVLGSVLSGSATGCPPRCECSAQDRAVLCHRK
             ::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001       MLAGGVRSMPSPLLACWQPILLLVLGSVLSGSATGCPPRCECSAQDRAVLCHRK
                     10        20        30        40        50    

               70        80        90       100       110       120
pF1KSD RFVAVPEGIPTETRLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RFVAVPEGIPTETRLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFN
           60        70        80        90       100       110    

              130       140       150       160       170       180
pF1KSD LRTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLV
          120       130       140       150       160       170    

              190       200       210       220       230       240
pF1KSD YISHRAFSGLNSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YISHRAFSGLNSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYR
          180       190       200       210       220       230    

              250       260       270       280       290       300
pF1KSD LKVLEISHWPYLDTMTPNCLYGLNLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKVLEISHWPYLDTMTPNCLYGLNLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPIS
          240       250       260       270       280       290    

              310       320       330       340       350       360
pF1KSD TIEGSMLHELLRLQEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TIEGSMLHELLRLQEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGN
          300       310       320       330       340       350    

              370       380       390       400       410       420
pF1KSD LETLILDSNPLACDCRLLWVFRRRWRLNFNRQQPTCATPEFVQGKEFKDFPDVLLPNYFT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LETLILDSNPLACDCRLLWVFRRRWRLNFNRQQPTCATPEFVQGKEFKDFPDVLLPNYFT
          360       370       380       390       400       410    

              430       440       450       460       470       480
pF1KSD CRRARIRDRKAQQVFVDEGHTVQFVCRADGDPPPAILWLSPRKHLVSAKSNGRLTVFPDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CRRARIRDRKAQQVFVDEGHTVQFVCRADGDPPPAILWLSPRKHLVSAKSNGRLTVFPDG
          420       430       440       450       460       470    

              490       500       510       520       530       540
pF1KSD TLEVRYAQVQDNGTYLCIAANAGGNDSMPAHLHVRSYSPDWPHQPNKTFAFISNQPGEGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLEVRYAQVQDNGTYLCIAANAGGNDSMPAHLHVRSYSPDWPHQPNKTFAFISNQPGEGE
          480       490       500       510       520       530    

              550       560       570       580       590       600
pF1KSD ANSTRATVPFPFDIKTLIIATTMGFISFLGVVLFCLVLLFLWSRGKGNTKHNIEIEYVPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ANSTRATVPFPFDIKTLIIATTMGFISFLGVVLFCLVLLFLWSRGKGNTKHNIEIEYVPR
          540       550       560       570       580       590    

              610       620
pF1KSD KSDAGISSADAPRKFNMKMI
       ::::::::::::::::::::
NP_001 KSDAGISSADAPRKFNMKMI
          600       610    

>>NP_001288126 (OMIM: 609791) leucine-rich repeat and im  (614 aa)
 initn: 4112 init1: 4112 opt: 4112  Z-score: 2508.2  bits: 474.2 E(85289): 5.7e-133
Smith-Waterman score: 4112; 100.0% identity (100.0% similar) in 614 aa overlap (7-620:1-614)

               10        20        30        40        50        60
pF1KSD MQVSKRMLAGGVRSMPSPLLACWQPILLLVLGSVLSGSATGCPPRCECSAQDRAVLCHRK
             ::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001       MLAGGVRSMPSPLLACWQPILLLVLGSVLSGSATGCPPRCECSAQDRAVLCHRK
                     10        20        30        40        50    

               70        80        90       100       110       120
pF1KSD RFVAVPEGIPTETRLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RFVAVPEGIPTETRLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFN
           60        70        80        90       100       110    

              130       140       150       160       170       180
pF1KSD LRTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLV
          120       130       140       150       160       170    

              190       200       210       220       230       240
pF1KSD YISHRAFSGLNSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YISHRAFSGLNSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYR
          180       190       200       210       220       230    

              250       260       270       280       290       300
pF1KSD LKVLEISHWPYLDTMTPNCLYGLNLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKVLEISHWPYLDTMTPNCLYGLNLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPIS
          240       250       260       270       280       290    

              310       320       330       340       350       360
pF1KSD TIEGSMLHELLRLQEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TIEGSMLHELLRLQEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGN
          300       310       320       330       340       350    

              370       380       390       400       410       420
pF1KSD LETLILDSNPLACDCRLLWVFRRRWRLNFNRQQPTCATPEFVQGKEFKDFPDVLLPNYFT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LETLILDSNPLACDCRLLWVFRRRWRLNFNRQQPTCATPEFVQGKEFKDFPDVLLPNYFT
          360       370       380       390       400       410    

              430       440       450       460       470       480
pF1KSD CRRARIRDRKAQQVFVDEGHTVQFVCRADGDPPPAILWLSPRKHLVSAKSNGRLTVFPDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CRRARIRDRKAQQVFVDEGHTVQFVCRADGDPPPAILWLSPRKHLVSAKSNGRLTVFPDG
          420       430       440       450       460       470    

              490       500       510       520       530       540
pF1KSD TLEVRYAQVQDNGTYLCIAANAGGNDSMPAHLHVRSYSPDWPHQPNKTFAFISNQPGEGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLEVRYAQVQDNGTYLCIAANAGGNDSMPAHLHVRSYSPDWPHQPNKTFAFISNQPGEGE
          480       490       500       510       520       530    

              550       560       570       580       590       600
pF1KSD ANSTRATVPFPFDIKTLIIATTMGFISFLGVVLFCLVLLFLWSRGKGNTKHNIEIEYVPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ANSTRATVPFPFDIKTLIIATTMGFISFLGVVLFCLVLLFLWSRGKGNTKHNIEIEYVPR
          540       550       560       570       580       590    

              610       620
pF1KSD KSDAGISSADAPRKFNMKMI
       ::::::::::::::::::::
NP_001 KSDAGISSADAPRKFNMKMI
          600       610    

>>NP_001288115 (OMIM: 609791) leucine-rich repeat and im  (614 aa)
 initn: 4112 init1: 4112 opt: 4112  Z-score: 2508.2  bits: 474.2 E(85289): 5.7e-133
Smith-Waterman score: 4112; 100.0% identity (100.0% similar) in 614 aa overlap (7-620:1-614)

               10        20        30        40        50        60
pF1KSD MQVSKRMLAGGVRSMPSPLLACWQPILLLVLGSVLSGSATGCPPRCECSAQDRAVLCHRK
             ::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001       MLAGGVRSMPSPLLACWQPILLLVLGSVLSGSATGCPPRCECSAQDRAVLCHRK
                     10        20        30        40        50    

               70        80        90       100       110       120
pF1KSD RFVAVPEGIPTETRLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RFVAVPEGIPTETRLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFN
           60        70        80        90       100       110    

              130       140       150       160       170       180
pF1KSD LRTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLV
          120       130       140       150       160       170    

              190       200       210       220       230       240
pF1KSD YISHRAFSGLNSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YISHRAFSGLNSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYR
          180       190       200       210       220       230    

              250       260       270       280       290       300
pF1KSD LKVLEISHWPYLDTMTPNCLYGLNLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKVLEISHWPYLDTMTPNCLYGLNLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPIS
          240       250       260       270       280       290    

              310       320       330       340       350       360
pF1KSD TIEGSMLHELLRLQEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TIEGSMLHELLRLQEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGN
          300       310       320       330       340       350    

              370       380       390       400       410       420
pF1KSD LETLILDSNPLACDCRLLWVFRRRWRLNFNRQQPTCATPEFVQGKEFKDFPDVLLPNYFT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LETLILDSNPLACDCRLLWVFRRRWRLNFNRQQPTCATPEFVQGKEFKDFPDVLLPNYFT
          360       370       380       390       400       410    

              430       440       450       460       470       480
pF1KSD CRRARIRDRKAQQVFVDEGHTVQFVCRADGDPPPAILWLSPRKHLVSAKSNGRLTVFPDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CRRARIRDRKAQQVFVDEGHTVQFVCRADGDPPPAILWLSPRKHLVSAKSNGRLTVFPDG
          420       430       440       450       460       470    

              490       500       510       520       530       540
pF1KSD TLEVRYAQVQDNGTYLCIAANAGGNDSMPAHLHVRSYSPDWPHQPNKTFAFISNQPGEGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLEVRYAQVQDNGTYLCIAANAGGNDSMPAHLHVRSYSPDWPHQPNKTFAFISNQPGEGE
          480       490       500       510       520       530    

              550       560       570       580       590       600
pF1KSD ANSTRATVPFPFDIKTLIIATTMGFISFLGVVLFCLVLLFLWSRGKGNTKHNIEIEYVPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ANSTRATVPFPFDIKTLIIATTMGFISFLGVVLFCLVLLFLWSRGKGNTKHNIEIEYVPR
          540       550       560       570       580       590    

              610       620
pF1KSD KSDAGISSADAPRKFNMKMI
       ::::::::::::::::::::
NP_001 KSDAGISSADAPRKFNMKMI
          600       610    

>>NP_001288120 (OMIM: 609791) leucine-rich repeat and im  (614 aa)
 initn: 4112 init1: 4112 opt: 4112  Z-score: 2508.2  bits: 474.2 E(85289): 5.7e-133
Smith-Waterman score: 4112; 100.0% identity (100.0% similar) in 614 aa overlap (7-620:1-614)

               10        20        30        40        50        60
pF1KSD MQVSKRMLAGGVRSMPSPLLACWQPILLLVLGSVLSGSATGCPPRCECSAQDRAVLCHRK
             ::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001       MLAGGVRSMPSPLLACWQPILLLVLGSVLSGSATGCPPRCECSAQDRAVLCHRK
                     10        20        30        40        50    

               70        80        90       100       110       120
pF1KSD RFVAVPEGIPTETRLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RFVAVPEGIPTETRLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFN
           60        70        80        90       100       110    

              130       140       150       160       170       180
pF1KSD LRTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLV
          120       130       140       150       160       170    

              190       200       210       220       230       240
pF1KSD YISHRAFSGLNSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YISHRAFSGLNSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYR
          180       190       200       210       220       230    

              250       260       270       280       290       300
pF1KSD LKVLEISHWPYLDTMTPNCLYGLNLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKVLEISHWPYLDTMTPNCLYGLNLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPIS
          240       250       260       270       280       290    

              310       320       330       340       350       360
pF1KSD TIEGSMLHELLRLQEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TIEGSMLHELLRLQEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGN
          300       310       320       330       340       350    

              370       380       390       400       410       420
pF1KSD LETLILDSNPLACDCRLLWVFRRRWRLNFNRQQPTCATPEFVQGKEFKDFPDVLLPNYFT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LETLILDSNPLACDCRLLWVFRRRWRLNFNRQQPTCATPEFVQGKEFKDFPDVLLPNYFT
          360       370       380       390       400       410    

              430       440       450       460       470       480
pF1KSD CRRARIRDRKAQQVFVDEGHTVQFVCRADGDPPPAILWLSPRKHLVSAKSNGRLTVFPDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CRRARIRDRKAQQVFVDEGHTVQFVCRADGDPPPAILWLSPRKHLVSAKSNGRLTVFPDG
          420       430       440       450       460       470    

              490       500       510       520       530       540
pF1KSD TLEVRYAQVQDNGTYLCIAANAGGNDSMPAHLHVRSYSPDWPHQPNKTFAFISNQPGEGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLEVRYAQVQDNGTYLCIAANAGGNDSMPAHLHVRSYSPDWPHQPNKTFAFISNQPGEGE
          480       490       500       510       520       530    

              550       560       570       580       590       600
pF1KSD ANSTRATVPFPFDIKTLIIATTMGFISFLGVVLFCLVLLFLWSRGKGNTKHNIEIEYVPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ANSTRATVPFPFDIKTLIIATTMGFISFLGVVLFCLVLLFLWSRGKGNTKHNIEIEYVPR
          540       550       560       570       580       590    

              610       620
pF1KSD KSDAGISSADAPRKFNMKMI
       ::::::::::::::::::::
NP_001 KSDAGISSADAPRKFNMKMI
          600       610    




620 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 08:16:47 2016 done: Thu Nov  3 08:16:48 2016
 Total Scan time:  8.140 Total Display time:  0.140

Function used was FASTA [36.3.4 Apr, 2011]
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