Result of FASTA (omim) for pF1KSDA1872
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KSDA1872, 371 aa
  1>>>pF1KSDA1872 371 - 371 aa - 371 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.8765+/-0.000321; mu= 13.8889+/- 0.020
 mean_var=79.0580+/-15.916, 0's: 0 Z-trim(115.9): 50  B-trim: 1400 in 1/58
 Lambda= 0.144245
 statistics sampled from 26536 (26592) to 26536 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.685), E-opt: 0.2 (0.312), width:  16
 Scan time:  8.720

The best scores are:                                      opt bits E(85289)
NP_149053 (OMIM: 601238,608179) caytaxin [Homo sap ( 371) 2476 524.7 1.3e-148
XP_006717047 (OMIM: 610691) PREDICTED: protein pru (3101) 1252 270.5 3.7e-71
XP_006717045 (OMIM: 610691) PREDICTED: protein pru (3104) 1250 270.1   5e-71
XP_011516628 (OMIM: 610691) PREDICTED: protein pru (3085) 1247 269.4 7.7e-71
XP_005251808 (OMIM: 610691) PREDICTED: protein pru (3075) 1246 269.2 8.8e-71
XP_011516630 (OMIM: 610691) PREDICTED: protein pru (3072) 1245 269.0   1e-70
XP_005251803 (OMIM: 610691) PREDICTED: protein pru (3091) 1245 269.0   1e-70
XP_005251802 (OMIM: 610691) PREDICTED: protein pru (3092) 1235 266.9 4.3e-70
NP_001294977 (OMIM: 610691) protein prune homolog  (3063) 1215 262.8 7.7e-69
XP_016869842 (OMIM: 610691) PREDICTED: protein pru (3068) 1215 262.8 7.7e-69
XP_011516629 (OMIM: 610691) PREDICTED: protein pru (3079) 1215 262.8 7.7e-69
XP_016869843 (OMIM: 610691) PREDICTED: protein pru ( 365) 1019 221.5 2.4e-57
XP_016869848 (OMIM: 610691) PREDICTED: protein pru ( 336) 1015 220.7   4e-57
XP_006717049 (OMIM: 610691) PREDICTED: protein pru (3100) 1027 223.6 4.6e-57
XP_016869845 (OMIM: 610691) PREDICTED: protein pru ( 352) 1014 220.5 4.8e-57
XP_016869847 (OMIM: 610691) PREDICTED: protein pru ( 337) 1012 220.0 6.2e-57
NP_001294978 (OMIM: 610691) protein prune homolog  ( 337) 1012 220.0 6.2e-57
NP_001294979 (OMIM: 610691) protein prune homolog  ( 352) 1012 220.0 6.4e-57
XP_016869841 (OMIM: 610691) PREDICTED: protein pru (3071) 1023 222.8 8.2e-57
XP_016869835 (OMIM: 610691) PREDICTED: protein pru (3087) 1022 222.6 9.5e-57
NP_001307603 (OMIM: 603292) BCL2/adenovirus E1B 19 ( 447) 1008 219.3 1.4e-56
XP_006717048 (OMIM: 610691) PREDICTED: protein pru (3101) 1019 222.0 1.5e-56
NP_001317609 (OMIM: 610691) protein prune homolog  ( 353) 1004 218.4   2e-56
XP_016869840 (OMIM: 610691) PREDICTED: protein pru (3072) 1015 221.1 2.6e-56
XP_005251807 (OMIM: 610691) PREDICTED: protein pru (3088) 1014 220.9   3e-56
NP_056040 (OMIM: 610691) protein prune homolog 2 i (3088) 1012 220.5   4e-56
XP_006717046 (OMIM: 610691) PREDICTED: protein pru (3103) 1011 220.3 4.7e-56
XP_016869839 (OMIM: 610691) PREDICTED: protein pru (3074) 1007 219.5 8.3e-56
XP_005251805 (OMIM: 610691) PREDICTED: protein pru (3090) 1006 219.3 9.6e-56
XP_011516625 (OMIM: 610691) PREDICTED: protein pru (3089) 1004 218.9 1.3e-55
NP_001294980 (OMIM: 610691) protein prune homolog  ( 324)  984 214.2 3.4e-55
XP_016869846 (OMIM: 610691) PREDICTED: protein pru ( 340)  984 214.2 3.5e-55
XP_016869834 (OMIM: 610691) PREDICTED: protein pru (3091)  996 217.2 4.1e-55
XP_016869838 (OMIM: 610691) PREDICTED: protein pru (3075)  992 216.4 7.2e-55
NP_001307604 (OMIM: 603292) BCL2/adenovirus E1B 19 ( 376)  974 212.2 1.6e-54
NP_004321 (OMIM: 603292) BCL2/adenovirus E1B 19 kD ( 435)  974 212.2 1.8e-54
XP_005251811 (OMIM: 610691) PREDICTED: protein pru (3060)  984 214.7 2.3e-54
XP_016869837 (OMIM: 610691) PREDICTED: protein pru (3076)  984 214.7 2.3e-54
NP_612122 (OMIM: 611275) bcl-2/adenovirus E1B 19 k ( 357)  969 211.1 3.2e-54
NP_001294976 (OMIM: 610691) protein prune homolog  (3062)  976 213.0 7.2e-54
XP_016869836 (OMIM: 610691) PREDICTED: protein pru (3078)  976 213.0 7.2e-54
NP_001153114 (OMIM: 611275) bcl-2/adenovirus E1B 1 ( 275)  845 185.2 1.5e-46
XP_011507538 (OMIM: 611275) PREDICTED: bcl-2/adeno ( 343)  811 178.2 2.4e-44
XP_016855909 (OMIM: 611275) PREDICTED: bcl-2/adeno ( 191)  696 154.2 2.4e-37
NP_001185655 (OMIM: 609405) rho GTPase-activating  ( 305)  348 81.8 2.2e-15
XP_011518397 (OMIM: 602732) PREDICTED: rho GTPase- ( 439)  349 82.1 2.6e-15
NP_004299 (OMIM: 602732) rho GTPase-activating pro ( 439)  349 82.1 2.6e-15
NP_851852 (OMIM: 609405) rho GTPase-activating pro ( 433)  348 81.9   3e-15
XP_016873209 (OMIM: 602732) PREDICTED: rho GTPase- ( 395)  211 53.4 1.1e-06
NP_001017526 (OMIM: 609405) rho GTPase-activating  ( 464)  201 51.3 5.2e-06


>>NP_149053 (OMIM: 601238,608179) caytaxin [Homo sapiens  (371 aa)
 initn: 2476 init1: 2476 opt: 2476  Z-score: 2789.1  bits: 524.7 E(85289): 1.3e-148
Smith-Waterman score: 2476; 100.0% identity (100.0% similar) in 371 aa overlap (1-371:1-371)

               10        20        30        40        50        60
pF1KSD MGTTEATLRMENVDVKEEWQDEDLPRPLPEETGVELLGSPVEDTSSPPNTLNFNGAHRKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 MGTTEATLRMENVDVKEEWQDEDLPRPLPEETGVELLGSPVEDTSSPPNTLNFNGAHRKR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD KTLVAPEINISLDQSEGSLLSDDFLDTPDDLDINVDDIETPDETDSLEFLGNGNELEWED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 KTLVAPEINISLDQSEGSLLSDDFLDTPDDLDINVDDIETPDETDSLEFLGNGNELEWED
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD DTPVATAKNMPGDSADLFGDGTTEDGSAANGRLWRTVIIGEQEHRIDLHMIRPYMKVVTH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 DTPVATAKNMPGDSADLFGDGTTEDGSAANGRLWRTVIIGEQEHRIDLHMIRPYMKVVTH
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD GGYYGEGLNAIIVFAACFLPDSSLPDYHYIMENLFLYVISSLELLVAEDYMIVYLNGATP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 GGYYGEGLNAIIVFAACFLPDSSLPDYHYIMENLFLYVISSLELLVAEDYMIVYLNGATP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD RRRMPGIGWLKKCYQMIDRRLRKNLKSLIIVHPSWFIRTVLAISRPFISVKFINKIQYVH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 RRRMPGIGWLKKCYQMIDRRLRKNLKSLIIVHPSWFIRTVLAISRPFISVKFINKIQYVH
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD SLEDLEQLIPMEHVQIPDCVLQYEEERLKARRESARPQPEFVLPRSEEKPEVAPVENRSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 SLEDLEQLIPMEHVQIPDCVLQYEEERLKARRESARPQPEFVLPRSEEKPEVAPVENRSA
              310       320       330       340       350       360

              370 
pF1KSD LVSEDQETSMS
       :::::::::::
NP_149 LVSEDQETSMS
              370 

>>XP_006717047 (OMIM: 610691) PREDICTED: protein prune h  (3101 aa)
 initn: 1105 init1: 818 opt: 1252  Z-score: 1398.4  bits: 270.5 E(85289): 3.7e-71
Smith-Waterman score: 1276; 57.6% identity (79.7% similar) in 349 aa overlap (22-367:2763-3095)

                        10        20        30        40        50 
pF1KSD          MGTTEATLRMENVDVKEEWQDEDLPRPLPEETGVELLGSPVEDTSSPPNTL
                                     ::.   .: : :: :  : ..    :::.:
XP_006 KNMIPDTEMEEETEFLELGTRISRPNGLLSEDVGMDIPFEEGV-LSPSAADMRPEPPNSL
           2740      2750      2760      2770       2780      2790 

              60        70        80        90       100       110 
pF1KSD NFNGAHRKRKTLVAPEINISLDQSEGSLLSDDFLDTPDDLDINVDDIETPDETDSLEFLG
       ..: .: .:  :.::.::.::::::::.:::: ::.::..:::::...::::.::.:. :
XP_006 DLNDTHPRRIKLTAPNINLSLDQSEGSILSDDNLDSPDEIDINVDELDTPDEADSFEYTG
            2800      2810      2820      2830      2840      2850 

             120       130       140       150       160       170 
pF1KSD NGNELEWEDDTPVATAKNMPGDSADLFGDGTTEDGSAANGRLWRTVIIGEQEHRIDLHMI
       .      ::  :  ::..  :. .. . . :.:.    : ::::::.:::::.:::...:
XP_006 H------ED--P--TANKDSGQESESIPEYTAEEEREDN-RLWRTVVIGEQEQRIDMKVI
                      2860      2870      2880       2890      2900

             180          190       200       210       220        
pF1KSD RPYMKVVTHGG---YYGEGLNAIIVFAACFLPDSSLPDYHYIMENLFLYVISSLELLVAE
       .:: .:..:::   :::.:::::::::::::::::  ::::.::::::::::.:::.:::
XP_006 EPYRRVISHGGDSGYYGDGLNAIIVFAACFLPDSSRADYHYVMENLFLYVISTLELMVAE
             2910      2920      2930      2940      2950      2960

      230       240       250       260       270       280        
pF1KSD DYMIVYLNGATPRRRMPGIGWLKKCYQMIDRRLRKNLKSLIIVHPSWFIRTVLAISRPFI
       ::::::::::::::::::.::.:::::::::::::::::.:::::::::::.::..::::
XP_006 DYMIVYLNGATPRRRMPGLGWMKKCYQMIDRRLRKNLKSFIIVHPSWFIRTILAVTRPFI
             2970      2980      2990      3000      3010      3020

      290       300       310       320       330       340        
pF1KSD SVKFINKIQYVHSLEDLEQLIPMEHVQIPDCVLQYEEERLKARRESARPQPEFVLPRSEE
       : :: .::.::.:: .:  ::::. ..::. ...:.:::  . ..:.: . :  : .. :
XP_006 SSKFSSKIKYVNSLSELSGLIPMDCIHIPESIIKYDEER--SYKRSVRLDEE--LREASE
             3030      3040      3050        3060      3070        

      350       360       370   
pF1KSD KPEVAPVENRSALVSEDQETSMS  
         ... . :   . : ..:      
XP_006 AAKTSCLYNDPEMSSMEKEKLCCVH
       3080      3090      3100 

>>XP_006717045 (OMIM: 610691) PREDICTED: protein prune h  (3104 aa)
 initn: 1105 init1: 818 opt: 1250  Z-score: 1396.2  bits: 270.1 E(85289): 5e-71
Smith-Waterman score: 1274; 57.4% identity (79.0% similar) in 352 aa overlap (22-370:2763-3092)

                        10        20        30        40        50 
pF1KSD          MGTTEATLRMENVDVKEEWQDEDLPRPLPEETGVELLGSPVEDTSSPPNTL
                                     ::.   .: : :: :  : ..    :::.:
XP_006 KNMIPDTEMEEETEFLELGTRISRPNGLLSEDVGMDIPFEEGV-LSPSAADMRPEPPNSL
           2740      2750      2760      2770       2780      2790 

              60        70        80        90       100       110 
pF1KSD NFNGAHRKRKTLVAPEINISLDQSEGSLLSDDFLDTPDDLDINVDDIETPDETDSLEFLG
       ..: .: .:  :.::.::.::::::::.:::: ::.::..:::::...::::.::.:. :
XP_006 DLNDTHPRRIKLTAPNINLSLDQSEGSILSDDNLDSPDEIDINVDELDTPDEADSFEYTG
            2800      2810      2820      2830      2840      2850 

             120       130       140       150       160       170 
pF1KSD NGNELEWEDDTPVATAKNMPGDSADLFGDGTTEDGSAANGRLWRTVIIGEQEHRIDLHMI
       .      ::  :  ::..  :. .. . . :.:.    : ::::::.:::::.:::...:
XP_006 H------ED--P--TANKDSGQESESIPEYTAEEEREDN-RLWRTVVIGEQEQRIDMKVI
                      2860      2870      2880       2890      2900

             180          190       200       210       220        
pF1KSD RPYMKVVTHGG---YYGEGLNAIIVFAACFLPDSSLPDYHYIMENLFLYVISSLELLVAE
       .:: .:..:::   :::.:::::::::::::::::  ::::.::::::::::.:::.:::
XP_006 EPYRRVISHGGDSGYYGDGLNAIIVFAACFLPDSSRADYHYVMENLFLYVISTLELMVAE
             2910      2920      2930      2940      2950      2960

      230       240       250       260       270       280        
pF1KSD DYMIVYLNGATPRRRMPGIGWLKKCYQMIDRRLRKNLKSLIIVHPSWFIRTVLAISRPFI
       ::::::::::::::::::.::.:::::::::::::::::.:::::::::::.::..::::
XP_006 DYMIVYLNGATPRRRMPGLGWMKKCYQMIDRRLRKNLKSFIIVHPSWFIRTILAVTRPFI
             2970      2980      2990      3000      3010      3020

      290       300       310       320       330       340        
pF1KSD SVKFINKIQYVHSLEDLEQLIPMEHVQIPDCVLQYEEERLKARRESARPQPEFVLPRSEE
       : :: .::.::.:: .:  ::::. ..::. ...:.:::  . ..:.:         .::
XP_006 SSKFSSKIKYVNSLSELSGLIPMDCIHIPESIIKYDEER--SYKRSVR--------LDEE
             3030      3040      3050        3060              3070

      350       360       370            
pF1KSD KPEVAPVENRSALVSEDQETSMS           
         :.. . . : : .. . .::            
XP_006 LREASEAAKTSCLYNDPEMSSMEKDIDLKLKEKP
             3080      3090      3100    

>>XP_011516628 (OMIM: 610691) PREDICTED: protein prune h  (3085 aa)
 initn: 1105 init1: 818 opt: 1247  Z-score: 1392.8  bits: 269.4 E(85289): 7.7e-71
Smith-Waterman score: 1271; 60.7% identity (82.0% similar) in 323 aa overlap (22-341:2763-3071)

                        10        20        30        40        50 
pF1KSD          MGTTEATLRMENVDVKEEWQDEDLPRPLPEETGVELLGSPVEDTSSPPNTL
                                     ::.   .: : :: :  : ..    :::.:
XP_011 KNMIPDTEMEEETEFLELGTRISRPNGLLSEDVGMDIPFEEGV-LSPSAADMRPEPPNSL
           2740      2750      2760      2770       2780      2790 

              60        70        80        90       100       110 
pF1KSD NFNGAHRKRKTLVAPEINISLDQSEGSLLSDDFLDTPDDLDINVDDIETPDETDSLEFLG
       ..: .: .:  :.::.::.::::::::.:::: ::.::..:::::...::::.::.:. :
XP_011 DLNDTHPRRIKLTAPNINLSLDQSEGSILSDDNLDSPDEIDINVDELDTPDEADSFEYTG
            2800      2810      2820      2830      2840      2850 

             120       130       140       150       160       170 
pF1KSD NGNELEWEDDTPVATAKNMPGDSADLFGDGTTEDGSAANGRLWRTVIIGEQEHRIDLHMI
       .      ::  :  ::..  :. .. . . :.:.    : ::::::.:::::.:::...:
XP_011 H------ED--P--TANKDSGQESESIPEYTAEEEREDN-RLWRTVVIGEQEQRIDMKVI
                      2860      2870      2880       2890      2900

             180          190       200       210       220        
pF1KSD RPYMKVVTHGG---YYGEGLNAIIVFAACFLPDSSLPDYHYIMENLFLYVISSLELLVAE
       .:: .:..:::   :::.:::::::::::::::::  ::::.::::::::::.:::.:::
XP_011 EPYRRVISHGGDSGYYGDGLNAIIVFAACFLPDSSRADYHYVMENLFLYVISTLELMVAE
             2910      2920      2930      2940      2950      2960

      230       240       250       260       270       280        
pF1KSD DYMIVYLNGATPRRRMPGIGWLKKCYQMIDRRLRKNLKSLIIVHPSWFIRTVLAISRPFI
       ::::::::::::::::::.::.:::::::::::::::::.:::::::::::.::..::::
XP_011 DYMIVYLNGATPRRRMPGLGWMKKCYQMIDRRLRKNLKSFIIVHPSWFIRTILAVTRPFI
             2970      2980      2990      3000      3010      3020

      290       300       310       320       330       340        
pF1KSD SVKFINKIQYVHSLEDLEQLIPMEHVQIPDCVLQYEEERLKARRESARPQPEFVLPRSEE
       : :: .::.::.:: .:  ::::. ..::. ...:.:::  . ..:.: . :.       
XP_011 SSKFSSKIKYVNSLSELSGLIPMDCIHIPESIIKYDEER--SYKRSVRLDEELREASEAA
             3030      3040      3050        3060      3070        

      350       360       370 
pF1KSD KPEVAPVENRSALVSEDQETSMS
                              
XP_011 KKLCCVH                
     3080                     

>>XP_005251808 (OMIM: 610691) PREDICTED: protein prune h  (3075 aa)
 initn: 1142 init1: 818 opt: 1246  Z-score: 1391.7  bits: 269.2 E(85289): 8.8e-71
Smith-Waterman score: 1270; 61.7% identity (81.6% similar) in 316 aa overlap (22-334:2763-3066)

                        10        20        30        40        50 
pF1KSD          MGTTEATLRMENVDVKEEWQDEDLPRPLPEETGVELLGSPVEDTSSPPNTL
                                     ::.   .: : :: :  : ..    :::.:
XP_005 KNMIPDTEMEEETEFLELGTRISRPNGLLSEDVGMDIPFEEGV-LSPSAADMRPEPPNSL
           2740      2750      2760      2770       2780      2790 

              60        70        80        90       100       110 
pF1KSD NFNGAHRKRKTLVAPEINISLDQSEGSLLSDDFLDTPDDLDINVDDIETPDETDSLEFLG
       ..: .: .:  :.::.::.::::::::.:::: ::.::..:::::...::::.::.:. :
XP_005 DLNDTHPRRIKLTAPNINLSLDQSEGSILSDDNLDSPDEIDINVDELDTPDEADSFEYTG
            2800      2810      2820      2830      2840      2850 

             120       130       140       150       160       170 
pF1KSD NGNELEWEDDTPVATAKNMPGDSADLFGDGTTEDGSAANGRLWRTVIIGEQEHRIDLHMI
       .      ::  :  ::..  :. .. . . :.:.    : ::::::.:::::.:::...:
XP_005 H------ED--P--TANKDSGQESESIPEYTAEEEREDN-RLWRTVVIGEQEQRIDMKVI
                      2860      2870      2880       2890      2900

             180          190       200       210       220        
pF1KSD RPYMKVVTHGG---YYGEGLNAIIVFAACFLPDSSLPDYHYIMENLFLYVISSLELLVAE
       .:: .:..:::   :::.:::::::::::::::::  ::::.::::::::::.:::.:::
XP_005 EPYRRVISHGGDSGYYGDGLNAIIVFAACFLPDSSRADYHYVMENLFLYVISTLELMVAE
             2910      2920      2930      2940      2950      2960

      230       240       250       260       270       280        
pF1KSD DYMIVYLNGATPRRRMPGIGWLKKCYQMIDRRLRKNLKSLIIVHPSWFIRTVLAISRPFI
       ::::::::::::::::::.::.:::::::::::::::::.:::::::::::.::..::::
XP_005 DYMIVYLNGATPRRRMPGLGWMKKCYQMIDRRLRKNLKSFIIVHPSWFIRTILAVTRPFI
             2970      2980      2990      3000      3010      3020

      290       300       310       320       330       340        
pF1KSD SVKFINKIQYVHSLEDLEQLIPMEHVQIPDCVLQYEEERLKARRESARPQPEFVLPRSEE
       : :: .::.::.:: .:  ::::. ..::. ...:.:::   :  :              
XP_005 SSKFSSKIKYVNSLSELSGLIPMDCIHIPESIIKYDEERSYKRSVSIDLKLKEKP     
             3030      3040      3050      3060      3070          

      350       360       370 
pF1KSD KPEVAPVENRSALVSEDQETSMS

>>XP_011516630 (OMIM: 610691) PREDICTED: protein prune h  (3072 aa)
 initn: 1142 init1: 818 opt: 1245  Z-score: 1390.6  bits: 269.0 E(85289): 1e-70
Smith-Waterman score: 1269; 62.0% identity (82.1% similar) in 313 aa overlap (22-331:2763-3063)

                        10        20        30        40        50 
pF1KSD          MGTTEATLRMENVDVKEEWQDEDLPRPLPEETGVELLGSPVEDTSSPPNTL
                                     ::.   .: : :: :  : ..    :::.:
XP_011 KNMIPDTEMEEETEFLELGTRISRPNGLLSEDVGMDIPFEEGV-LSPSAADMRPEPPNSL
           2740      2750      2760      2770       2780      2790 

              60        70        80        90       100       110 
pF1KSD NFNGAHRKRKTLVAPEINISLDQSEGSLLSDDFLDTPDDLDINVDDIETPDETDSLEFLG
       ..: .: .:  :.::.::.::::::::.:::: ::.::..:::::...::::.::.:. :
XP_011 DLNDTHPRRIKLTAPNINLSLDQSEGSILSDDNLDSPDEIDINVDELDTPDEADSFEYTG
            2800      2810      2820      2830      2840      2850 

             120       130       140       150       160       170 
pF1KSD NGNELEWEDDTPVATAKNMPGDSADLFGDGTTEDGSAANGRLWRTVIIGEQEHRIDLHMI
       .      ::  :  ::..  :. .. . . :.:.    : ::::::.:::::.:::...:
XP_011 H------ED--P--TANKDSGQESESIPEYTAEEEREDN-RLWRTVVIGEQEQRIDMKVI
                      2860      2870      2880       2890      2900

             180          190       200       210       220        
pF1KSD RPYMKVVTHGG---YYGEGLNAIIVFAACFLPDSSLPDYHYIMENLFLYVISSLELLVAE
       .:: .:..:::   :::.:::::::::::::::::  ::::.::::::::::.:::.:::
XP_011 EPYRRVISHGGDSGYYGDGLNAIIVFAACFLPDSSRADYHYVMENLFLYVISTLELMVAE
             2910      2920      2930      2940      2950      2960

      230       240       250       260       270       280        
pF1KSD DYMIVYLNGATPRRRMPGIGWLKKCYQMIDRRLRKNLKSLIIVHPSWFIRTVLAISRPFI
       ::::::::::::::::::.::.:::::::::::::::::.:::::::::::.::..::::
XP_011 DYMIVYLNGATPRRRMPGLGWMKKCYQMIDRRLRKNLKSFIIVHPSWFIRTILAVTRPFI
             2970      2980      2990      3000      3010      3020

      290       300       310       320       330       340        
pF1KSD SVKFINKIQYVHSLEDLEQLIPMEHVQIPDCVLQYEEERLKARRESARPQPEFVLPRSEE
       : :: .::.::.:: .:  ::::. ..::. ...:.:::   :                 
XP_011 SSKFSSKIKYVNSLSELSGLIPMDCIHIPESIIKYDEERSYKRSVRKLCCVH        
             3030      3040      3050      3060      3070          

      350       360       370 
pF1KSD KPEVAPVENRSALVSEDQETSMS

>>XP_005251803 (OMIM: 610691) PREDICTED: protein prune h  (3091 aa)
 initn: 1143 init1: 819 opt: 1245  Z-score: 1390.6  bits: 269.0 E(85289): 1e-70
Smith-Waterman score: 1269; 62.0% identity (82.1% similar) in 313 aa overlap (22-331:2763-3063)

                        10        20        30        40        50 
pF1KSD          MGTTEATLRMENVDVKEEWQDEDLPRPLPEETGVELLGSPVEDTSSPPNTL
                                     ::.   .: : :: :  : ..    :::.:
XP_005 KNMIPDTEMEEETEFLELGTRISRPNGLLSEDVGMDIPFEEGV-LSPSAADMRPEPPNSL
           2740      2750      2760      2770       2780      2790 

              60        70        80        90       100       110 
pF1KSD NFNGAHRKRKTLVAPEINISLDQSEGSLLSDDFLDTPDDLDINVDDIETPDETDSLEFLG
       ..: .: .:  :.::.::.::::::::.:::: ::.::..:::::...::::.::.:. :
XP_005 DLNDTHPRRIKLTAPNINLSLDQSEGSILSDDNLDSPDEIDINVDELDTPDEADSFEYTG
            2800      2810      2820      2830      2840      2850 

             120       130       140       150       160       170 
pF1KSD NGNELEWEDDTPVATAKNMPGDSADLFGDGTTEDGSAANGRLWRTVIIGEQEHRIDLHMI
       .      ::  :  ::..  :. .. . . :.:.    : ::::::.:::::.:::...:
XP_005 H------ED--P--TANKDSGQESESIPEYTAEEEREDN-RLWRTVVIGEQEQRIDMKVI
                      2860      2870      2880       2890      2900

             180          190       200       210       220        
pF1KSD RPYMKVVTHGG---YYGEGLNAIIVFAACFLPDSSLPDYHYIMENLFLYVISSLELLVAE
       .:: .:..:::   :::.:::::::::::::::::  ::::.::::::::::.:::.:::
XP_005 EPYRRVISHGGDSGYYGDGLNAIIVFAACFLPDSSRADYHYVMENLFLYVISTLELMVAE
             2910      2920      2930      2940      2950      2960

      230       240       250       260       270       280        
pF1KSD DYMIVYLNGATPRRRMPGIGWLKKCYQMIDRRLRKNLKSLIIVHPSWFIRTVLAISRPFI
       ::::::::::::::::::.::.:::::::::::::::::.:::::::::::.::..::::
XP_005 DYMIVYLNGATPRRRMPGLGWMKKCYQMIDRRLRKNLKSFIIVHPSWFIRTILAVTRPFI
             2970      2980      2990      3000      3010      3020

      290       300       310       320       330       340        
pF1KSD SVKFINKIQYVHSLEDLEQLIPMEHVQIPDCVLQYEEERLKARRESARPQPEFVLPRSEE
       : :: .::.::.:: .:  ::::. ..::. ...:.:::   :                 
XP_005 SSKFSSKIKYVNSLSELSGLIPMDCIHIPESIIKYDEERSYKRSVRTSCLYNDPEMSSME
             3030      3040      3050      3060      3070      3080

      350       360       370 
pF1KSD KPEVAPVENRSALVSEDQETSMS
                              
XP_005 KDIDLKLKEKP            
             3090             

>>XP_005251802 (OMIM: 610691) PREDICTED: protein prune h  (3092 aa)
 initn: 1126 init1: 802 opt: 1235  Z-score: 1379.3  bits: 266.9 E(85289): 4.3e-70
Smith-Waterman score: 1259; 61.0% identity (81.8% similar) in 318 aa overlap (22-336:2763-3067)

                        10        20        30        40        50 
pF1KSD          MGTTEATLRMENVDVKEEWQDEDLPRPLPEETGVELLGSPVEDTSSPPNTL
                                     ::.   .: : :: :  : ..    :::.:
XP_005 KNMIPDTEMEEETEFLELGTRISRPNGLLSEDVGMDIPFEEGV-LSPSAADMRPEPPNSL
           2740      2750      2760      2770       2780      2790 

              60        70        80        90       100       110 
pF1KSD NFNGAHRKRKTLVAPEINISLDQSEGSLLSDDFLDTPDDLDINVDDIETPDETDSLEFLG
       ..: .: .:  :.::.::.::::::::.:::: ::.::..:::::...::::.::.:. :
XP_005 DLNDTHPRRIKLTAPNINLSLDQSEGSILSDDNLDSPDEIDINVDELDTPDEADSFEYTG
            2800      2810      2820      2830      2840      2850 

             120       130       140       150       160       170 
pF1KSD NGNELEWEDDTPVATAKNMPGDSADLFGDGTTEDGSAANGRLWRTVIIGEQEHRIDLHMI
       .      ::  :  ::..  :. .. . . :.:.    : ::::::.:::::.:::...:
XP_005 H------ED--P--TANKDSGQESESIPEYTAEEEREDN-RLWRTVVIGEQEQRIDMKVI
                      2860      2870      2880       2890      2900

             180          190       200       210       220        
pF1KSD RPYMKVVTHGG---YYGEGLNAIIVFAACFLPDSSLPDYHYIMENLFLYVISSLELLVAE
       .:: .:..:::   :::.:::::::::::::::::  ::::.::::::::::.:::.:::
XP_005 EPYRRVISHGGDSGYYGDGLNAIIVFAACFLPDSSRADYHYVMENLFLYVISTLELMVAE
             2910      2920      2930      2940      2950      2960

      230       240       250       260       270       280        
pF1KSD DYMIVYLNGATPRRRMPGIGWLKKCYQMIDRRLRKNLKSLIIVHPSWFIRTVLAISRPFI
       ::::::::::::::::::.::.:::::::::::::::::.:::::::::::.::..::::
XP_005 DYMIVYLNGATPRRRMPGLGWMKKCYQMIDRRLRKNLKSFIIVHPSWFIRTILAVTRPFI
             2970      2980      2990      3000      3010      3020

      290       300       310       320       330       340        
pF1KSD SVKFINKIQYVHSLEDLEQLIPMEHVQIPDCVLQYEEERLKARRESARPQPEFVLPRSEE
       : :: .::.::.:: .:  ::::. ..::. ... .:: :.   :.:.            
XP_005 SSKFSSKIKYVNSLSELSGLIPMDCIHIPESIIKLDEE-LREASEAAKTSCLYNDPEMSS
             3030      3040      3050       3060      3070         

      350       360       370 
pF1KSD KPEVAPVENRSALVSEDQETSMS
                              
XP_005 MEKDIDLKLKEKP          
    3080      3090            

>>NP_001294977 (OMIM: 610691) protein prune homolog 2 is  (3063 aa)
 initn: 1269 init1: 788 opt: 1215  Z-score: 1356.9  bits: 262.8 E(85289): 7.7e-69
Smith-Waterman score: 1239; 61.0% identity (81.8% similar) in 313 aa overlap (22-331:2763-3062)

                        10        20        30        40        50 
pF1KSD          MGTTEATLRMENVDVKEEWQDEDLPRPLPEETGVELLGSPVEDTSSPPNTL
                                     ::.   .: : :: :  : ..    :::.:
NP_001 KNMIPDTEMEEETEFLELGTRISRPNGLLSEDVGMDIPFEEGV-LSPSAADMRPEPPNSL
           2740      2750      2760      2770       2780      2790 

              60        70        80        90       100       110 
pF1KSD NFNGAHRKRKTLVAPEINISLDQSEGSLLSDDFLDTPDDLDINVDDIETPDETDSLEFLG
       ..: .: .:  :.::.::.::::::::.:::: ::.::..:::::...::::.::.:. :
NP_001 DLNDTHPRRIKLTAPNINLSLDQSEGSILSDDNLDSPDEIDINVDELDTPDEADSFEYTG
            2800      2810      2820      2830      2840      2850 

             120       130       140       150       160       170 
pF1KSD NGNELEWEDDTPVATAKNMPGDSADLFGDGTTEDGSAANGRLWRTVIIGEQEHRIDLHMI
       .      ::  :  ::..  :. .. . . :.:.    : ::::::.:::::.:::...:
NP_001 H------ED--P--TANKDSGQESESIPEYTAEEEREDN-RLWRTVVIGEQEQRIDMKVI
                      2860      2870      2880       2890      2900

             180          190       200       210       220        
pF1KSD RPYMKVVTHGG---YYGEGLNAIIVFAACFLPDSSLPDYHYIMENLFLYVISSLELLVAE
       .:: .:..:::   :::.:::::::::::::::::  ::::.::::::::::.:::.:::
NP_001 EPYRRVISHGGDSGYYGDGLNAIIVFAACFLPDSSRADYHYVMENLFLYVISTLELMVAE
             2910      2920      2930      2940      2950      2960

      230       240       250       260       270       280        
pF1KSD DYMIVYLNGATPRRRMPGIGWLKKCYQMIDRRLRKNLKSLIIVHPSWFIRTVLAISRPFI
       ::::::::::::::::::.::.:::::::::::::::::.:::::::::::.::..::::
NP_001 DYMIVYLNGATPRRRMPGLGWMKKCYQMIDRRLRKNLKSFIIVHPSWFIRTILAVTRPFI
             2970      2980      2990      3000      3010      3020

      290       300       310       320       330       340        
pF1KSD SVKFINKIQYVHSLEDLEQLIPMEHVQIPDCVLQYEEERLKARRESARPQPEFVLPRSEE
       : :: .::.::.:: .:  ::::. ..::. ... .  .:: .                 
NP_001 SSKFSSKIKYVNSLSELSGLIPMDCIHIPESIINIDL-KLKEKP                
             3030      3040      3050       3060                   

      350       360       370 
pF1KSD KPEVAPVENRSALVSEDQETSMS

>>XP_016869842 (OMIM: 610691) PREDICTED: protein prune h  (3068 aa)
 initn: 1267 init1: 789 opt: 1215  Z-score: 1356.9  bits: 262.8 E(85289): 7.7e-69
Smith-Waterman score: 1239; 62.2% identity (82.6% similar) in 304 aa overlap (22-322:2763-3054)

                        10        20        30        40        50 
pF1KSD          MGTTEATLRMENVDVKEEWQDEDLPRPLPEETGVELLGSPVEDTSSPPNTL
                                     ::.   .: : :: :  : ..    :::.:
XP_016 KNMIPDTEMEEETEFLELGTRISRPNGLLSEDVGMDIPFEEGV-LSPSAADMRPEPPNSL
           2740      2750      2760      2770       2780      2790 

              60        70        80        90       100       110 
pF1KSD NFNGAHRKRKTLVAPEINISLDQSEGSLLSDDFLDTPDDLDINVDDIETPDETDSLEFLG
       ..: .: .:  :.::.::.::::::::.:::: ::.::..:::::...::::.::.:. :
XP_016 DLNDTHPRRIKLTAPNINLSLDQSEGSILSDDNLDSPDEIDINVDELDTPDEADSFEYTG
            2800      2810      2820      2830      2840      2850 

             120       130       140       150       160       170 
pF1KSD NGNELEWEDDTPVATAKNMPGDSADLFGDGTTEDGSAANGRLWRTVIIGEQEHRIDLHMI
       .      ::  :  ::..  :. .. . . :.:.    : ::::::.:::::.:::...:
XP_016 H------ED--P--TANKDSGQESESIPEYTAEEEREDN-RLWRTVVIGEQEQRIDMKVI
                      2860      2870      2880       2890      2900

             180          190       200       210       220        
pF1KSD RPYMKVVTHGG---YYGEGLNAIIVFAACFLPDSSLPDYHYIMENLFLYVISSLELLVAE
       .:: .:..:::   :::.:::::::::::::::::  ::::.::::::::::.:::.:::
XP_016 EPYRRVISHGGDSGYYGDGLNAIIVFAACFLPDSSRADYHYVMENLFLYVISTLELMVAE
             2910      2920      2930      2940      2950      2960

      230       240       250       260       270       280        
pF1KSD DYMIVYLNGATPRRRMPGIGWLKKCYQMIDRRLRKNLKSLIIVHPSWFIRTVLAISRPFI
       ::::::::::::::::::.::.:::::::::::::::::.:::::::::::.::..::::
XP_016 DYMIVYLNGATPRRRMPGLGWMKKCYQMIDRRLRKNLKSFIIVHPSWFIRTILAVTRPFI
             2970      2980      2990      3000      3010      3020

      290       300       310       320       330       340        
pF1KSD SVKFINKIQYVHSLEDLEQLIPMEHVQIPDCVLQYEEERLKARRESARPQPEFVLPRSEE
       : :: .::.::.:: .:  ::::. ..::. ...                          
XP_016 SSKFSSKIKYVNSLSELSGLIPMDCIHIPESIIKCRGRNLVGSYLCTV            
             3030      3040      3050      3060                    

      350       360       370 
pF1KSD KPEVAPVENRSALVSEDQETSMS




371 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 07:34:08 2016 done: Thu Nov  3 07:34:09 2016
 Total Scan time:  8.720 Total Display time:  0.040

Function used was FASTA [36.3.4 Apr, 2011]
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