Result of FASTA (omim) for pF1KSDA1830
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KSDA1830, 454 aa
  1>>>pF1KSDA1830 454 - 454 aa - 454 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.4399+/-0.000392; mu= 17.3547+/- 0.024
 mean_var=68.0044+/-14.174, 0's: 0 Z-trim(110.8): 37  B-trim: 944 in 1/51
 Lambda= 0.155527
 statistics sampled from 19251 (19288) to 19251 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.585), E-opt: 0.2 (0.226), width:  16
 Scan time:  8.800

The best scores are:                                      opt bits E(85289)
NP_061895 (OMIM: 616102) protein disulfide-isomera ( 454) 3012 685.1  1e-196
XP_011524335 (OMIM: 616102) PREDICTED: protein dis ( 313) 2037 466.2 5.4e-131
XP_005266771 (OMIM: 616102) PREDICTED: protein dis ( 313) 2037 466.2 5.4e-131
XP_011524337 (OMIM: 616102) PREDICTED: protein dis ( 229) 1443 332.9 5.5e-91
XP_011524336 (OMIM: 616102) PREDICTED: protein dis ( 231) 1441 332.4 7.5e-91
NP_000909 (OMIM: 112240,176790) protein disulfide- ( 508)  320 81.1 7.6e-15
NP_005304 (OMIM: 602046) protein disulfide-isomera ( 505)  299 76.4   2e-13
XP_011508610 (OMIM: 611099) PREDICTED: protein dis ( 402)  282 72.5 2.3e-12
NP_001269636 (OMIM: 611099) protein disulfide-isom ( 437)  282 72.5 2.5e-12
NP_005733 (OMIM: 611099) protein disulfide-isomera ( 440)  282 72.5 2.5e-12
NP_001269635 (OMIM: 611099) protein disulfide-isom ( 445)  282 72.5 2.5e-12
NP_001269634 (OMIM: 611099) protein disulfide-isom ( 488)  282 72.6 2.7e-12
NP_001269633 (OMIM: 611099) protein disulfide-isom ( 492)  282 72.6 2.7e-12
NP_001139021 (OMIM: 616412) thioredoxin domain-con ( 324)  242 63.5 9.7e-10
NP_110437 (OMIM: 616412) thioredoxin domain-contai ( 432)  242 63.6 1.2e-09
NP_110382 (OMIM: 610527) thioredoxin-related trans ( 280)  227 60.1 8.8e-09
NP_006840 (OMIM: 608012) protein disulfide-isomera ( 525)  223 59.3 2.8e-08
NP_001258510 (OMIM: 607987) dnaJ homolog subfamily ( 747)  201 54.5 1.2e-06
NP_061854 (OMIM: 607987) dnaJ homolog subfamily C  ( 793)  201 54.5 1.2e-06
NP_006801 (OMIM: 616942) protein disulfide-isomera ( 519)  196 53.3 1.8e-06
NP_001004128 (OMIM: 603120) sulfhydryl oxidase 1 i ( 604)  176 48.8 4.7e-05
NP_002817 (OMIM: 603120) sulfhydryl oxidase 1 isof ( 747)  176 48.9 5.6e-05
NP_055866 (OMIM: 609170) endoplasmic reticulum res ( 406)  170 47.4 8.5e-05
NP_859052 (OMIM: 612860) sulfhydryl oxidase 2 prec ( 698)  171 47.7 0.00012
NP_001222 (OMIM: 114250,616231) calsequestrin-1 pr ( 396)  166 46.5 0.00016
NP_036605 (OMIM: 609063,616811) thioredoxin, mitoc ( 166)  156 44.0 0.00035
XP_006724289 (OMIM: 609063,616811) PREDICTED: thio ( 166)  156 44.0 0.00035
NP_066979 (OMIM: 616766) thioredoxin-related trans ( 349)  160 45.1 0.00036
XP_005261565 (OMIM: 609063,616811) PREDICTED: thio ( 197)  156 44.1 0.00041
NP_001223 (OMIM: 114251,604772,611938) calsequestr ( 399)  147 42.2   0.003


>>NP_061895 (OMIM: 616102) protein disulfide-isomerase T  (454 aa)
 initn: 3012 init1: 3012 opt: 3012  Z-score: 3652.7  bits: 685.1 E(85289): 1e-196
Smith-Waterman score: 3012; 100.0% identity (100.0% similar) in 454 aa overlap (1-454:1-454)

               10        20        30        40        50        60
pF1KSD MAAWKSWTALRLCATVVVLDMVVCKGFVEDLDESFKENRNDDIWLVDFYAPWCGHCKKLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 MAAWKSWTALRLCATVVVLDMVVCKGFVEDLDESFKENRNDDIWLVDFYAPWCGHCKKLE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD PIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKLLKGDLAYNYRGPRTKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 PIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKLLKGDLAYNYRGPRTKD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD DIIEFAHRVSGALIRPLPSQQMFEHMQKRHRVFFVYVGGESPLKEKYIDAASELIVYTYF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 DIIEFAHRVSGALIRPLPSQQMFEHMQKRHRVFFVYVGGESPLKEKYIDAASELIVYTYF
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD FSASEEVVPEYVTLKEMPAVLVFKDETYFVYDEYEDGDLSSWINRERFQNYLAMDGFLLY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 FSASEEVVPEYVTLKEMPAVLVFKDETYFVYDEYEDGDLSSWINRERFQNYLAMDGFLLY
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD ELGDTGKLVALAVIDEKNTSVEHTRLKSIIQEVARDYRDLFHRDFQFGHMDGNDYINTLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 ELGDTGKLVALAVIDEKNTSVEHTRLKSIIQEVARDYRDLFHRDFQFGHMDGNDYINTLL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD MDELTVPTVVVLNTSNQQYFLLDRQIKNVEDMVQFINNILDGTVEAQGGDSILQRLKRIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 MDELTVPTVVVLNTSNQQYFLLDRQIKNVEDMVQFINNILDGTVEAQGGDSILQRLKRIV
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD FDAKSTIVSIFKSSPLMGCFLFGLPLGVISIMCYGIYTADTDGGYIEERYEVSKSENENQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 FDAKSTIVSIFKSSPLMGCFLFGLPLGVISIMCYGIYTADTDGGYIEERYEVSKSENENQ
              370       380       390       400       410       420

              430       440       450    
pF1KSD EQIEESKEQQEPSSGGSVVPTVQEPKDVLEKKKD
       ::::::::::::::::::::::::::::::::::
NP_061 EQIEESKEQQEPSSGGSVVPTVQEPKDVLEKKKD
              430       440       450    

>>XP_011524335 (OMIM: 616102) PREDICTED: protein disulfi  (313 aa)
 initn: 2037 init1: 2037 opt: 2037  Z-score: 2472.8  bits: 466.2 E(85289): 5.4e-131
Smith-Waterman score: 2037; 100.0% identity (100.0% similar) in 313 aa overlap (142-454:1-313)

             120       130       140       150       160       170 
pF1KSD NYRGPRTKDDIIEFAHRVSGALIRPLPSQQMFEHMQKRHRVFFVYVGGESPLKEKYIDAA
                                     ::::::::::::::::::::::::::::::
XP_011                               MFEHMQKRHRVFFVYVGGESPLKEKYIDAA
                                             10        20        30

             180       190       200       210       220       230 
pF1KSD SELIVYTYFFSASEEVVPEYVTLKEMPAVLVFKDETYFVYDEYEDGDLSSWINRERFQNY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SELIVYTYFFSASEEVVPEYVTLKEMPAVLVFKDETYFVYDEYEDGDLSSWINRERFQNY
               40        50        60        70        80        90

             240       250       260       270       280       290 
pF1KSD LAMDGFLLYELGDTGKLVALAVIDEKNTSVEHTRLKSIIQEVARDYRDLFHRDFQFGHMD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAMDGFLLYELGDTGKLVALAVIDEKNTSVEHTRLKSIIQEVARDYRDLFHRDFQFGHMD
              100       110       120       130       140       150

             300       310       320       330       340       350 
pF1KSD GNDYINTLLMDELTVPTVVVLNTSNQQYFLLDRQIKNVEDMVQFINNILDGTVEAQGGDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GNDYINTLLMDELTVPTVVVLNTSNQQYFLLDRQIKNVEDMVQFINNILDGTVEAQGGDS
              160       170       180       190       200       210

             360       370       380       390       400       410 
pF1KSD ILQRLKRIVFDAKSTIVSIFKSSPLMGCFLFGLPLGVISIMCYGIYTADTDGGYIEERYE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILQRLKRIVFDAKSTIVSIFKSSPLMGCFLFGLPLGVISIMCYGIYTADTDGGYIEERYE
              220       230       240       250       260       270

             420       430       440       450    
pF1KSD VSKSENENQEQIEESKEQQEPSSGGSVVPTVQEPKDVLEKKKD
       :::::::::::::::::::::::::::::::::::::::::::
XP_011 VSKSENENQEQIEESKEQQEPSSGGSVVPTVQEPKDVLEKKKD
              280       290       300       310   

>>XP_005266771 (OMIM: 616102) PREDICTED: protein disulfi  (313 aa)
 initn: 2037 init1: 2037 opt: 2037  Z-score: 2472.8  bits: 466.2 E(85289): 5.4e-131
Smith-Waterman score: 2037; 100.0% identity (100.0% similar) in 313 aa overlap (142-454:1-313)

             120       130       140       150       160       170 
pF1KSD NYRGPRTKDDIIEFAHRVSGALIRPLPSQQMFEHMQKRHRVFFVYVGGESPLKEKYIDAA
                                     ::::::::::::::::::::::::::::::
XP_005                               MFEHMQKRHRVFFVYVGGESPLKEKYIDAA
                                             10        20        30

             180       190       200       210       220       230 
pF1KSD SELIVYTYFFSASEEVVPEYVTLKEMPAVLVFKDETYFVYDEYEDGDLSSWINRERFQNY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SELIVYTYFFSASEEVVPEYVTLKEMPAVLVFKDETYFVYDEYEDGDLSSWINRERFQNY
               40        50        60        70        80        90

             240       250       260       270       280       290 
pF1KSD LAMDGFLLYELGDTGKLVALAVIDEKNTSVEHTRLKSIIQEVARDYRDLFHRDFQFGHMD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LAMDGFLLYELGDTGKLVALAVIDEKNTSVEHTRLKSIIQEVARDYRDLFHRDFQFGHMD
              100       110       120       130       140       150

             300       310       320       330       340       350 
pF1KSD GNDYINTLLMDELTVPTVVVLNTSNQQYFLLDRQIKNVEDMVQFINNILDGTVEAQGGDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GNDYINTLLMDELTVPTVVVLNTSNQQYFLLDRQIKNVEDMVQFINNILDGTVEAQGGDS
              160       170       180       190       200       210

             360       370       380       390       400       410 
pF1KSD ILQRLKRIVFDAKSTIVSIFKSSPLMGCFLFGLPLGVISIMCYGIYTADTDGGYIEERYE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ILQRLKRIVFDAKSTIVSIFKSSPLMGCFLFGLPLGVISIMCYGIYTADTDGGYIEERYE
              220       230       240       250       260       270

             420       430       440       450    
pF1KSD VSKSENENQEQIEESKEQQEPSSGGSVVPTVQEPKDVLEKKKD
       :::::::::::::::::::::::::::::::::::::::::::
XP_005 VSKSENENQEQIEESKEQQEPSSGGSVVPTVQEPKDVLEKKKD
              280       290       300       310   

>>XP_011524337 (OMIM: 616102) PREDICTED: protein disulfi  (229 aa)
 initn: 1461 init1: 1440 opt: 1443  Z-score: 1754.5  bits: 332.9 E(85289): 5.5e-91
Smith-Waterman score: 1443; 93.9% identity (96.9% similar) in 228 aa overlap (1-228:1-225)

               10        20        30        40        50        60
pF1KSD MAAWKSWTALRLCATVVVLDMVVCKGFVEDLDESFKENRNDDIWLVDFYAPWCGHCKKLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAAWKSWTALRLCATVVVLDMVVCKGFVEDLDESFKENRNDDIWLVDFYAPWCGHCKKLE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD PIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKLLKGDLAYNYRGPRTKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKLLKGDLAYNYRGPRTKD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD DIIEFAHRVSGALIRPLPSQQMFEHMQKRHRVFFVYVGGESPLKEKYIDAASELIVYTYF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DIIEFAHRVSGALIRPLPSQQMFEHMQKRHRVFFVYVGGESPLKEKYIDAASELIVYTYF
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD FSASEEVVPEYVTLKEMPAVLVFKDETYFVYDEYEDGDLSSWINRERFQNYLAMDGFLLY
       ::::::::::::::::::::::::::::::::   :.. .  .. .:.            
XP_011 FSASEEVVPEYVTLKEMPAVLVFKDETYFVYD---DNNYTLMLSYKRYYLHT        
              190       200       210          220                 

              250       260       270       280       290       300
pF1KSD ELGDTGKLVALAVIDEKNTSVEHTRLKSIIQEVARDYRDLFHRDFQFGHMDGNDYINTLL

>>XP_011524336 (OMIM: 616102) PREDICTED: protein disulfi  (231 aa)
 initn: 1462 init1: 1441 opt: 1441  Z-score: 1752.1  bits: 332.4 E(85289): 7.5e-91
Smith-Waterman score: 1441; 99.1% identity (99.5% similar) in 214 aa overlap (1-214:1-214)

               10        20        30        40        50        60
pF1KSD MAAWKSWTALRLCATVVVLDMVVCKGFVEDLDESFKENRNDDIWLVDFYAPWCGHCKKLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAAWKSWTALRLCATVVVLDMVVCKGFVEDLDESFKENRNDDIWLVDFYAPWCGHCKKLE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD PIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKLLKGDLAYNYRGPRTKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKLLKGDLAYNYRGPRTKD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD DIIEFAHRVSGALIRPLPSQQMFEHMQKRHRVFFVYVGGESPLKEKYIDAASELIVYTYF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DIIEFAHRVSGALIRPLPSQQMFEHMQKRHRVFFVYVGGESPLKEKYIDAASELIVYTYF
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD FSASEEVVPEYVTLKEMPAVLVFKDETYFVYDEYEDGDLSSWINRERFQNYLAMDGFLLY
       :::::::::::::::::::::::::::::::: .                          
XP_011 FSASEEVVPEYVTLKEMPAVLVFKDETYFVYDAFILDSESTCAGLLHGCIG         
              190       200       210       220       230          

              250       260       270       280       290       300
pF1KSD ELGDTGKLVALAVIDEKNTSVEHTRLKSIIQEVARDYRDLFHRDFQFGHMDGNDYINTLL

>>NP_000909 (OMIM: 112240,176790) protein disulfide-isom  (508 aa)
 initn: 288 init1: 249 opt: 320  Z-score: 387.5  bits: 81.1 E(85289): 7.6e-15
Smith-Waterman score: 320; 31.3% identity (63.6% similar) in 195 aa overlap (45-232:45-229)

           20        30        40        50        60        70    
pF1KSD TVVVLDMVVCKGFVEDLDESFKENRNDDIWLVDFYAPWCGHCKKLEPIWNEVGLEMKSIG
                                     ::.:::::::::: : : . ... ..:. :
NP_000 VRADAPEEEDHVLVLRKSNFAEALAAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEG
           20        30        40        50        60        70    

           80        90       100        110         120       130 
pF1KSD SPVKVGKMDATSYSSIASEFGVRGYPTIKLLK-GDLAY--NYRGPRTKDDIIEFAHRVSG
       : ....:.:::  :..:...:::::::::... :: :   .: . :  :::... .. .:
NP_000 SEIRLAKVDATEESDLAQQYGVRGYPTIKFFRNGDTASPKEYTAGREADDIVNWLKKRTG
           80        90       100       110       120       130    

             140       150           160       170       180       
pF1KSD ALIRPLPSQQMFEHMQKRHRV----FFVYVGGESPLKEKYIDAASELIVYTYFFSASEEV
            ::.    : . .  .:    ::  :  ::   .....::  .    . .... .:
NP_000 PAATTLPDGAAAESLVESSEVAVIGFFKDV--ESDSAKQFLQAAEAIDDIPFGITSNSDV
          140       150       160         170       180       190  

       190       200       210       220       230       240       
pF1KSD VPEYVTLKEMPAVLVFKDETYFVYDEYEDGDLSSWINRERFQNYLAMDGFLLYELGDTGK
         .:   :.  .:..::      .:: .. .. . ...: . ...               
NP_000 FSKYQLDKD--GVVLFKK-----FDEGRN-NFEGEVTKENLLDFIKHNQLPLVIEFTEQT
            200              210        220       230       240    

       250       260       270       280       290       300       
pF1KSD LVALAVIDEKNTSVEHTRLKSIIQEVARDYRDLFHRDFQFGHMDGNDYINTLLMDELTVP
                                                                   
NP_000 APKIFGGEIKTHILLFLPKSVSDYDGKLSNFKTAAESFKGKILFIFIDSDHTDNQRILEF
          250       260       270       280       290       300    

>--
 initn: 178 init1: 154 opt: 216  Z-score: 261.4  bits: 57.8 E(85289): 8.1e-08
Smith-Waterman score: 216; 37.0% identity (67.6% similar) in 108 aa overlap (21-125:371-469)

                         10        20        30        40        50
pF1KSD           MAAWKSWTALRLCATVVVLDMVVCKGFVEDLDESFKENRNDDIWLVDFYA
                                     ..: :.: ::.  .: :..:    .:.:::
NP_000 EFCHRFLEGKIKPHLMSQELPEDWDKQPVKVLVGKNF-EDV--AFDEKKN---VFVEFYA
              350       360       370        380            390    

               60        70        80        90       100          
pF1KSD PWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKLLKGD--
       :::::::.: :::...:  .:.    . ..:::.:.    : .  :...::.:.. ..  
NP_000 PWCGHCKQLAPIWDKLGETYKD-HENIVIAKMDSTANEVEAVK--VHSFPTLKFFPASAD
          400       410        420       430         440       450 

       110       120       130       140       150       160       
pF1KSD -LAYNYRGPRTKDDIIEFAHRVSGALIRPLPSQQMFEHMQKRHRVFFVYVGGESPLKEKY
         . .: : :: : . .:                                          
NP_000 RTVIDYNGERTLDGFKKFLESGGQDGAGDDDDLEDLEEAEEPDMEEDDDQKAVKDEL   
             460       470       480       490       500           

>>NP_005304 (OMIM: 602046) protein disulfide-isomerase A  (505 aa)
 initn: 229 init1: 134 opt: 299  Z-score: 362.1  bits: 76.4 E(85289): 2e-13
Smith-Waterman score: 339; 24.7% identity (59.3% similar) in 344 aa overlap (28-345:28-362)

               10        20        30        40             50     
pF1KSD MAAWKSWTALRLCATVVVLDMVVCKGFVEDLDESFKENRNDD-----IWLVDFYAPWCGH
                                  .:  :..: :.: .:     . ::.:.::::::
NP_005 MRLRRLALFPGVALLLAAARLAAASDVLELTDDNF-ESRISDTGSAGLMLVEFFAPWCGH
               10        20        30         40        50         

          60        70        80        90       100        110    
pF1KSD CKKLEPIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKLLK-GDLAYNYR
       ::.: : .. .. ..:.:   : ..:.: :. ..  ...:: ::::.:... :. :  : 
NP_005 CKRLAPEYEAAATRLKGI---VPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGAYD
      60        70           80        90       100       110      

          120       130       140         150       160       170  
pF1KSD GPRTKDDIIEFAHRVSGALIRPLPSQQMFEHM--QKRHRVFFVYVGGESPLKEKYIDAAS
       :::: : :.   .. .:    :: ... :...  .:   .   .  . :  . ... :::
NP_005 GPRTADGIVSHLKKQAGPASVPLRTEEEFKKFISDKDASIVGFFDDSFSEAHSEFLKAAS
        120       130       140       150       160       170      

             180       190            200          210       220   
pF1KSD ELI-VYTYFFSASEEVVPEYVTLKE-----MPAVLV--FKDETY-FVYDEYEDGDLSSWI
       .:   : .  .  : .: ::    :      :. :.  :.:.:  .. ... .: ....:
NP_005 NLRDNYRFAHTNVESLVNEYDDNGEGIILFRPSHLTNKFEDKTVAYTEQKMTSGKIKKFI
        180       190       200       210       220       230      

             230       240       250       260       270       280 
pF1KSD NRERFQ--NYLAMDGFLLYELGDTGKLVALAVIDEKNTSVEHTRLKSIIQEVARDYRDLF
       ... :    ... :.  : .  :   :.:   .: ....   .  .. .. ::. . :  
NP_005 QENIFGICPHMTEDNKDLIQGKDL--LIAYYDVDYEKNAKGSNYWRNRVMMVAKKFLDAG
        240       250       260         270       280       290    

                    290       300       310       320       330    
pF1KSD HR-DFQ------FGHMDGNDYINTLLMDELTVPTVVVLNTSNQQYFLLDRQIKNVEDMVQ
       :. .:       :.: . .:.   :      .:.:.. ....... . ..  .. . . .
NP_005 HKLNFAVASRKTFSH-ELSDF--GLESTAGEIPVVAIRTAKGEKFVMQEEFSRDGKALER
          300        310         320       330       340       350 

          340       350       360       370       380       390    
pF1KSD FINNILDGTVEAQGGDSILQRLKRIVFDAKSTIVSIFKSSPLMGCFLFGLPLGVISIMCY
       :... .::...                                                 
NP_005 FLQDYFDGNLKRYLKSEPIPESNDGPVKVVVAENFDEIVNNENKDVLIEFYAPWCGHCKN
             360       370       380       390       400       410 

>--
 initn: 189 init1: 132 opt: 250  Z-score: 302.6  bits: 65.4 E(85289): 4.1e-10
Smith-Waterman score: 250; 41.7% identity (69.9% similar) in 103 aa overlap (29-128:384-482)

                 10        20        30        40        50        
pF1KSD   MAAWKSWTALRLCATVVVLDMVVCKGFVEDLDESFKENRNDDIWLVDFYAPWCGHCKK
                                     :..:: . .:.: :. :..::::::::::.
NP_005 QDYFDGNLKRYLKSEPIPESNDGPVKVVVAENFDE-IVNNENKDV-LIEFYAPWCGHCKN
           360       370       380        390        400       410 

       60        70        80        90       100       110        
pF1KSD LEPIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKLLKGDLAYN---YRG
       ::: ..:.: :  :    . ..:::::. ... : . :::.::: .  ..   :   :.:
NP_005 LEPKYKELG-EKLSKDPNIVIAKMDATA-NDVPSPYEVRGFPTIYFSPANKKLNPKKYEG
             420        430        440       450       460         

         120       130       140       150       160       170     
pF1KSD PRTKDDIIEFAHRVSGALIRPLPSQQMFEHMQKRHRVFFVYVGGESPLKEKYIDAASELI
        :  .:.: . .:                                               
NP_005 GRELSDFISYLQREATNPPVIQEEKPKKKKKAQEDL                        
     470       480       490       500                             

>>XP_011508610 (OMIM: 611099) PREDICTED: protein disulfi  (402 aa)
 initn: 405 init1: 159 opt: 282  Z-score: 343.0  bits: 72.5 E(85289): 2.3e-12
Smith-Waterman score: 329; 46.2% identity (72.6% similar) in 106 aa overlap (25-126:160-265)

                     10        20        30        40          50  
pF1KSD       MAAWKSWTALRLCATVVVLDMVVCKGFVEDLDESFKENRND--DIWLVDFYAPW
                                     :  .:  :.:: .:  :  :.:.:.:::::
XP_011 ALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLDSEDVWMVEFYAPW
     130       140       150       160       170       180         

             60        70         80        90       100        110
pF1KSD CGHCKKLEPIWNEVGLEMK-SIGSPVKVGKMDATSYSSIASEFGVRGYPTIKLL-KGDLA
       :::::.::: :  .. :.: .  . ::.. .:::  . .::..:.::.::::.. ::.  
XP_011 CGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDATVNQVLASRYGIRGFPTIKIFQKGESP
     190       200       210       220       230       240         

              120       130       140       150       160       170
pF1KSD YNYRGPRTKDDIIEFAHRVSGALIRPLPSQQMFEHMQKRHRVFFVYVGGESPLKEKYIDA
        .: : ::..::.  :                                            
XP_011 VDYDGGRTRSDIVSRALDLFSDNAPPPELLEIINEDIAKRTCEEHQLCVVAVLPHILDTG
     250       260       270       280       290       300         

>--
 initn: 276 init1: 159 opt: 282  Z-score: 343.0  bits: 72.5 E(85289): 2.3e-12
Smith-Waterman score: 282; 38.4% identity (74.7% similar) in 99 aa overlap (39-135:41-136)

       10        20        30        40        50        60        
pF1KSD ALRLCATVVVLDMVVCKGFVEDLDESFKENRNDDIWLVDFYAPWCGHCKKLEPIWNEVGL
                                     ..:..:::.:::::::::..: : :.... 
XP_011 CTFFLAVNGLYSSSDDVIELTPSNFNREVIQSDSLWLVEFYAPWCGHCQRLTPEWKKAAT
               20        30        40        50        60        70

       70        80        90       100       110         120      
pF1KSD EMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKLLKGDLAY--NYRGPRTKDDIIEFA
        .:..   :::: .:: .. :.....::.:.::::.. ..     .:.: :: . :.. :
XP_011 ALKDV---VKVGAVDADKHHSLGGQYGVQGFPTIKIFGSNKNRPEDYQGGRTGEAIVDAA
                  80        90       100       110       120       

        130       140       150       160       170       180      
pF1KSD HRVSGALIRPLPSQQMFEHMQKRHRVFFVYVGGESPLKEKYIDAASELIVYTYFFSASEE
         .   :..                                                   
XP_011 LSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLDSEDVWMVEFYA
       130       140       150       160       170       180       

>>NP_001269636 (OMIM: 611099) protein disulfide-isomeras  (437 aa)
 initn: 428 init1: 159 opt: 282  Z-score: 342.4  bits: 72.5 E(85289): 2.5e-12
Smith-Waterman score: 329; 46.2% identity (72.6% similar) in 106 aa overlap (25-126:157-262)

                     10        20        30        40          50  
pF1KSD       MAAWKSWTALRLCATVVVLDMVVCKGFVEDLDESFKENRND--DIWLVDFYAPW
                                     :  .:  :.:: .:  :  :.:.:.:::::
NP_001 ALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLDSEDVWMVEFYAPW
        130       140       150       160       170       180      

             60        70         80        90       100        110
pF1KSD CGHCKKLEPIWNEVGLEMK-SIGSPVKVGKMDATSYSSIASEFGVRGYPTIKLL-KGDLA
       :::::.::: :  .. :.: .  . ::.. .:::  . .::..:.::.::::.. ::.  
NP_001 CGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDATVNQVLASRYGIRGFPTIKIFQKGESP
        190       200       210       220       230       240      

              120       130       140       150       160       170
pF1KSD YNYRGPRTKDDIIEFAHRVSGALIRPLPSQQMFEHMQKRHRVFFVYVGGESPLKEKYIDA
        .: : ::..::.  :                                            
NP_001 VDYDGGRTRSDIVSRALDLFSDNAPPPELLEIINEDIAKRTCEEHQLCVVAVLPHILDTG
        250       260       270       280       290       300      

>--
 initn: 276 init1: 159 opt: 282  Z-score: 342.4  bits: 72.5 E(85289): 2.5e-12
Smith-Waterman score: 282; 38.4% identity (74.7% similar) in 99 aa overlap (39-135:38-133)

       10        20        30        40        50        60        
pF1KSD ALRLCATVVVLDMVVCKGFVEDLDESFKENRNDDIWLVDFYAPWCGHCKKLEPIWNEVGL
                                     ..:..:::.:::::::::..: : :.... 
NP_001 CTFFLAVNGLYSSSDDVIELTPSNFNREVIQSDSLWLVEFYAPWCGHCQRLTPEWKKAAT
        10        20        30        40        50        60       

       70        80        90       100       110         120      
pF1KSD EMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKLLKGDLAY--NYRGPRTKDDIIEFA
        .:..   :::: .:: .. :.....::.:.::::.. ..     .:.: :: . :.. :
NP_001 ALKDV---VKVGAVDADKHHSLGGQYGVQGFPTIKIFGSNKNRPEDYQGGRTGEAIVDAA
        70           80        90       100       110       120    

        130       140       150       160       170       180      
pF1KSD HRVSGALIRPLPSQQMFEHMQKRHRVFFVYVGGESPLKEKYIDAASELIVYTYFFSASEE
         .   :..                                                   
NP_001 LSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLDSEDVWMVEFYA
          130       140       150       160       170       180    

>>NP_005733 (OMIM: 611099) protein disulfide-isomerase A  (440 aa)
 initn: 428 init1: 159 opt: 282  Z-score: 342.4  bits: 72.5 E(85289): 2.5e-12
Smith-Waterman score: 329; 46.2% identity (72.6% similar) in 106 aa overlap (25-126:160-265)

                     10        20        30        40          50  
pF1KSD       MAAWKSWTALRLCATVVVLDMVVCKGFVEDLDESFKENRND--DIWLVDFYAPW
                                     :  .:  :.:: .:  :  :.:.:.:::::
NP_005 ALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLDSEDVWMVEFYAPW
     130       140       150       160       170       180         

             60        70         80        90       100        110
pF1KSD CGHCKKLEPIWNEVGLEMK-SIGSPVKVGKMDATSYSSIASEFGVRGYPTIKLL-KGDLA
       :::::.::: :  .. :.: .  . ::.. .:::  . .::..:.::.::::.. ::.  
NP_005 CGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDATVNQVLASRYGIRGFPTIKIFQKGESP
     190       200       210       220       230       240         

              120       130       140       150       160       170
pF1KSD YNYRGPRTKDDIIEFAHRVSGALIRPLPSQQMFEHMQKRHRVFFVYVGGESPLKEKYIDA
        .: : ::..::.  :                                            
NP_005 VDYDGGRTRSDIVSRALDLFSDNAPPPELLEIINEDIAKRTCEEHQLCVVAVLPHILDTG
     250       260       270       280       290       300         

>--
 initn: 276 init1: 159 opt: 282  Z-score: 342.4  bits: 72.5 E(85289): 2.5e-12
Smith-Waterman score: 282; 38.4% identity (74.7% similar) in 99 aa overlap (39-135:41-136)

       10        20        30        40        50        60        
pF1KSD ALRLCATVVVLDMVVCKGFVEDLDESFKENRNDDIWLVDFYAPWCGHCKKLEPIWNEVGL
                                     ..:..:::.:::::::::..: : :.... 
NP_005 CTFFLAVNGLYSSSDDVIELTPSNFNREVIQSDSLWLVEFYAPWCGHCQRLTPEWKKAAT
               20        30        40        50        60        70

       70        80        90       100       110         120      
pF1KSD EMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKLLKGDLAY--NYRGPRTKDDIIEFA
        .:..   :::: .:: .. :.....::.:.::::.. ..     .:.: :: . :.. :
NP_005 ALKDV---VKVGAVDADKHHSLGGQYGVQGFPTIKIFGSNKNRPEDYQGGRTGEAIVDAA
                  80        90       100       110       120       

        130       140       150       160       170       180      
pF1KSD HRVSGALIRPLPSQQMFEHMQKRHRVFFVYVGGESPLKEKYIDAASELIVYTYFFSASEE
         .   :..                                                   
NP_005 LSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLDSEDVWMVEFYA
       130       140       150       160       170       180       




454 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 07:27:25 2016 done: Thu Nov  3 07:27:27 2016
 Total Scan time:  8.800 Total Display time:  0.030

Function used was FASTA [36.3.4 Apr, 2011]
Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.com