Result of FASTA (omim) for pF1KSDA1585
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KSDA1585, 577 aa
  1>>>pF1KSDA1585 577 - 577 aa - 577 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.5152+/-0.00041; mu= 9.2067+/- 0.026
 mean_var=135.3396+/-26.778, 0's: 0 Z-trim(116.1): 17  B-trim: 0 in 0/54
 Lambda= 0.110246
 statistics sampled from 27043 (27056) to 27043 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.682), E-opt: 0.2 (0.317), width:  16
 Scan time: 10.500

The best scores are:                                      opt bits E(85289)
NP_060603 (OMIM: 614802) E3 ubiquitin-protein liga ( 577) 3849 624.0 4.2e-178
XP_011511251 (OMIM: 614802) PREDICTED: E3 ubiquiti ( 503) 3325 540.6 4.6e-153
XP_006713747 (OMIM: 614802) PREDICTED: E3 ubiquiti ( 503) 3325 540.6 4.6e-153
NP_001138889 (OMIM: 614802) E3 ubiquitin-protein l ( 503) 3325 540.6 4.6e-153
XP_005247628 (OMIM: 614802) PREDICTED: E3 ubiquiti ( 503) 3325 540.6 4.6e-153


>>NP_060603 (OMIM: 614802) E3 ubiquitin-protein ligase M  (577 aa)
 initn: 3849 init1: 3849 opt: 3849  Z-score: 3318.5  bits: 624.0 E(85289): 4.2e-178
Smith-Waterman score: 3849; 100.0% identity (100.0% similar) in 577 aa overlap (1-577:1-577)

               10        20        30        40        50        60
pF1KSD MNPVNATALYISASRLVLNYDPGDPKAFTEINRLLPYFRQSLSCCVCGHLLQDPIAPTNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 MNPVNATALYISASRLVLNYDPGDPKAFTEINRLLPYFRQSLSCCVCGHLLQDPIAPTNS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD TCQHYVCKTCKGKKMMMKPSCSWCKDYEQFEENKQLSILVNCYKKLCEYITQTTLARDII
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 TCQHYVCKTCKGKKMMMKPSCSWCKDYEQFEENKQLSILVNCYKKLCEYITQTTLARDII
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD EAVDCSSDILALLNDGSLFCEETEKPSDSSFTLCLTHSPLPSTSEPTTDPQASLSPMSES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 EAVDCSSDILALLNDGSLFCEETEKPSDSSFTLCLTHSPLPSTSEPTTDPQASLSPMSES
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD TLSIAIGSSVINGLPTYNGLSIDRFGINIPSPEHSNTIDVCNTVDIKTEDLSDSLPPVCD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 TLSIAIGSSVINGLPTYNGLSIDRFGINIPSPEHSNTIDVCNTVDIKTEDLSDSLPPVCD
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD TVATDLCSTGIDICSFSEDIKPGDSLLLSVEEVLRSLETVSNTEVCCPNLQPNLEATVSN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 TVATDLCSTGIDICSFSEDIKPGDSLLLSVEEVLRSLETVSNTEVCCPNLQPNLEATVSN
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD GPFLQLSSQSLSHNVFMSTSPALHGLSCTAATPKIAKLNRKRSRSESDSEKVQPLPISTI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 GPFLQLSSQSLSHNVFMSTSPALHGLSCTAATPKIAKLNRKRSRSESDSEKVQPLPISTI
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD IRGPTLGASAPVTVKRESKISLQPIATVPNGGTTPKISKTVLLSTKSMKKSHEHGSKKSH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 IRGPTLGASAPVTVKRESKISLQPIATVPNGGTTPKISKTVLLSTKSMKKSHEHGSKKSH
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD SKTKPGILKKDKAVKEKIPSHHFMPGSPTKTVYKKPQEKKGCKCGRATQNPSVLTCRGQR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 SKTKPGILKKDKAVKEKIPSHHFMPGSPTKTVYKKPQEKKGCKCGRATQNPSVLTCRGQR
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD CPCYSNRKACLDCICRGCQNSYMANGEKKLEAFAVPEKALEQTRLTLGINVTSIAVRNAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 CPCYSNRKACLDCICRGCQNSYMANGEKKLEAFAVPEKALEQTRLTLGINVTSIAVRNAS
              490       500       510       520       530       540

              550       560       570       
pF1KSD TSTSVINVTGSPVTTFLAASTHDDKSLDEAIDMRFDC
       :::::::::::::::::::::::::::::::::::::
NP_060 TSTSVINVTGSPVTTFLAASTHDDKSLDEAIDMRFDC
              550       560       570       

>>XP_011511251 (OMIM: 614802) PREDICTED: E3 ubiquitin-pr  (503 aa)
 initn: 3325 init1: 3325 opt: 3325  Z-score: 2869.0  bits: 540.6 E(85289): 4.6e-153
Smith-Waterman score: 3325; 100.0% identity (100.0% similar) in 503 aa overlap (75-577:1-503)

           50        60        70        80        90       100    
pF1KSD CVCGHLLQDPIAPTNSTCQHYVCKTCKGKKMMMKPSCSWCKDYEQFEENKQLSILVNCYK
                                     ::::::::::::::::::::::::::::::
XP_011                               MMMKPSCSWCKDYEQFEENKQLSILVNCYK
                                             10        20        30

          110       120       130       140       150       160    
pF1KSD KLCEYITQTTLARDIIEAVDCSSDILALLNDGSLFCEETEKPSDSSFTLCLTHSPLPSTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLCEYITQTTLARDIIEAVDCSSDILALLNDGSLFCEETEKPSDSSFTLCLTHSPLPSTS
               40        50        60        70        80        90

          170       180       190       200       210       220    
pF1KSD EPTTDPQASLSPMSESTLSIAIGSSVINGLPTYNGLSIDRFGINIPSPEHSNTIDVCNTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPTTDPQASLSPMSESTLSIAIGSSVINGLPTYNGLSIDRFGINIPSPEHSNTIDVCNTV
              100       110       120       130       140       150

          230       240       250       260       270       280    
pF1KSD DIKTEDLSDSLPPVCDTVATDLCSTGIDICSFSEDIKPGDSLLLSVEEVLRSLETVSNTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DIKTEDLSDSLPPVCDTVATDLCSTGIDICSFSEDIKPGDSLLLSVEEVLRSLETVSNTE
              160       170       180       190       200       210

          290       300       310       320       330       340    
pF1KSD VCCPNLQPNLEATVSNGPFLQLSSQSLSHNVFMSTSPALHGLSCTAATPKIAKLNRKRSR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VCCPNLQPNLEATVSNGPFLQLSSQSLSHNVFMSTSPALHGLSCTAATPKIAKLNRKRSR
              220       230       240       250       260       270

          350       360       370       380       390       400    
pF1KSD SESDSEKVQPLPISTIIRGPTLGASAPVTVKRESKISLQPIATVPNGGTTPKISKTVLLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SESDSEKVQPLPISTIIRGPTLGASAPVTVKRESKISLQPIATVPNGGTTPKISKTVLLS
              280       290       300       310       320       330

          410       420       430       440       450       460    
pF1KSD TKSMKKSHEHGSKKSHSKTKPGILKKDKAVKEKIPSHHFMPGSPTKTVYKKPQEKKGCKC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TKSMKKSHEHGSKKSHSKTKPGILKKDKAVKEKIPSHHFMPGSPTKTVYKKPQEKKGCKC
              340       350       360       370       380       390

          470       480       490       500       510       520    
pF1KSD GRATQNPSVLTCRGQRCPCYSNRKACLDCICRGCQNSYMANGEKKLEAFAVPEKALEQTR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GRATQNPSVLTCRGQRCPCYSNRKACLDCICRGCQNSYMANGEKKLEAFAVPEKALEQTR
              400       410       420       430       440       450

          530       540       550       560       570       
pF1KSD LTLGINVTSIAVRNASTSTSVINVTGSPVTTFLAASTHDDKSLDEAIDMRFDC
       :::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTLGINVTSIAVRNASTSTSVINVTGSPVTTFLAASTHDDKSLDEAIDMRFDC
              460       470       480       490       500   

>>XP_006713747 (OMIM: 614802) PREDICTED: E3 ubiquitin-pr  (503 aa)
 initn: 3325 init1: 3325 opt: 3325  Z-score: 2869.0  bits: 540.6 E(85289): 4.6e-153
Smith-Waterman score: 3325; 100.0% identity (100.0% similar) in 503 aa overlap (75-577:1-503)

           50        60        70        80        90       100    
pF1KSD CVCGHLLQDPIAPTNSTCQHYVCKTCKGKKMMMKPSCSWCKDYEQFEENKQLSILVNCYK
                                     ::::::::::::::::::::::::::::::
XP_006                               MMMKPSCSWCKDYEQFEENKQLSILVNCYK
                                             10        20        30

          110       120       130       140       150       160    
pF1KSD KLCEYITQTTLARDIIEAVDCSSDILALLNDGSLFCEETEKPSDSSFTLCLTHSPLPSTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KLCEYITQTTLARDIIEAVDCSSDILALLNDGSLFCEETEKPSDSSFTLCLTHSPLPSTS
               40        50        60        70        80        90

          170       180       190       200       210       220    
pF1KSD EPTTDPQASLSPMSESTLSIAIGSSVINGLPTYNGLSIDRFGINIPSPEHSNTIDVCNTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EPTTDPQASLSPMSESTLSIAIGSSVINGLPTYNGLSIDRFGINIPSPEHSNTIDVCNTV
              100       110       120       130       140       150

          230       240       250       260       270       280    
pF1KSD DIKTEDLSDSLPPVCDTVATDLCSTGIDICSFSEDIKPGDSLLLSVEEVLRSLETVSNTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DIKTEDLSDSLPPVCDTVATDLCSTGIDICSFSEDIKPGDSLLLSVEEVLRSLETVSNTE
              160       170       180       190       200       210

          290       300       310       320       330       340    
pF1KSD VCCPNLQPNLEATVSNGPFLQLSSQSLSHNVFMSTSPALHGLSCTAATPKIAKLNRKRSR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VCCPNLQPNLEATVSNGPFLQLSSQSLSHNVFMSTSPALHGLSCTAATPKIAKLNRKRSR
              220       230       240       250       260       270

          350       360       370       380       390       400    
pF1KSD SESDSEKVQPLPISTIIRGPTLGASAPVTVKRESKISLQPIATVPNGGTTPKISKTVLLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SESDSEKVQPLPISTIIRGPTLGASAPVTVKRESKISLQPIATVPNGGTTPKISKTVLLS
              280       290       300       310       320       330

          410       420       430       440       450       460    
pF1KSD TKSMKKSHEHGSKKSHSKTKPGILKKDKAVKEKIPSHHFMPGSPTKTVYKKPQEKKGCKC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TKSMKKSHEHGSKKSHSKTKPGILKKDKAVKEKIPSHHFMPGSPTKTVYKKPQEKKGCKC
              340       350       360       370       380       390

          470       480       490       500       510       520    
pF1KSD GRATQNPSVLTCRGQRCPCYSNRKACLDCICRGCQNSYMANGEKKLEAFAVPEKALEQTR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GRATQNPSVLTCRGQRCPCYSNRKACLDCICRGCQNSYMANGEKKLEAFAVPEKALEQTR
              400       410       420       430       440       450

          530       540       550       560       570       
pF1KSD LTLGINVTSIAVRNASTSTSVINVTGSPVTTFLAASTHDDKSLDEAIDMRFDC
       :::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LTLGINVTSIAVRNASTSTSVINVTGSPVTTFLAASTHDDKSLDEAIDMRFDC
              460       470       480       490       500   

>>NP_001138889 (OMIM: 614802) E3 ubiquitin-protein ligas  (503 aa)
 initn: 3325 init1: 3325 opt: 3325  Z-score: 2869.0  bits: 540.6 E(85289): 4.6e-153
Smith-Waterman score: 3325; 100.0% identity (100.0% similar) in 503 aa overlap (75-577:1-503)

           50        60        70        80        90       100    
pF1KSD CVCGHLLQDPIAPTNSTCQHYVCKTCKGKKMMMKPSCSWCKDYEQFEENKQLSILVNCYK
                                     ::::::::::::::::::::::::::::::
NP_001                               MMMKPSCSWCKDYEQFEENKQLSILVNCYK
                                             10        20        30

          110       120       130       140       150       160    
pF1KSD KLCEYITQTTLARDIIEAVDCSSDILALLNDGSLFCEETEKPSDSSFTLCLTHSPLPSTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLCEYITQTTLARDIIEAVDCSSDILALLNDGSLFCEETEKPSDSSFTLCLTHSPLPSTS
               40        50        60        70        80        90

          170       180       190       200       210       220    
pF1KSD EPTTDPQASLSPMSESTLSIAIGSSVINGLPTYNGLSIDRFGINIPSPEHSNTIDVCNTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EPTTDPQASLSPMSESTLSIAIGSSVINGLPTYNGLSIDRFGINIPSPEHSNTIDVCNTV
              100       110       120       130       140       150

          230       240       250       260       270       280    
pF1KSD DIKTEDLSDSLPPVCDTVATDLCSTGIDICSFSEDIKPGDSLLLSVEEVLRSLETVSNTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DIKTEDLSDSLPPVCDTVATDLCSTGIDICSFSEDIKPGDSLLLSVEEVLRSLETVSNTE
              160       170       180       190       200       210

          290       300       310       320       330       340    
pF1KSD VCCPNLQPNLEATVSNGPFLQLSSQSLSHNVFMSTSPALHGLSCTAATPKIAKLNRKRSR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VCCPNLQPNLEATVSNGPFLQLSSQSLSHNVFMSTSPALHGLSCTAATPKIAKLNRKRSR
              220       230       240       250       260       270

          350       360       370       380       390       400    
pF1KSD SESDSEKVQPLPISTIIRGPTLGASAPVTVKRESKISLQPIATVPNGGTTPKISKTVLLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SESDSEKVQPLPISTIIRGPTLGASAPVTVKRESKISLQPIATVPNGGTTPKISKTVLLS
              280       290       300       310       320       330

          410       420       430       440       450       460    
pF1KSD TKSMKKSHEHGSKKSHSKTKPGILKKDKAVKEKIPSHHFMPGSPTKTVYKKPQEKKGCKC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TKSMKKSHEHGSKKSHSKTKPGILKKDKAVKEKIPSHHFMPGSPTKTVYKKPQEKKGCKC
              340       350       360       370       380       390

          470       480       490       500       510       520    
pF1KSD GRATQNPSVLTCRGQRCPCYSNRKACLDCICRGCQNSYMANGEKKLEAFAVPEKALEQTR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GRATQNPSVLTCRGQRCPCYSNRKACLDCICRGCQNSYMANGEKKLEAFAVPEKALEQTR
              400       410       420       430       440       450

          530       540       550       560       570       
pF1KSD LTLGINVTSIAVRNASTSTSVINVTGSPVTTFLAASTHDDKSLDEAIDMRFDC
       :::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTLGINVTSIAVRNASTSTSVINVTGSPVTTFLAASTHDDKSLDEAIDMRFDC
              460       470       480       490       500   

>>XP_005247628 (OMIM: 614802) PREDICTED: E3 ubiquitin-pr  (503 aa)
 initn: 3325 init1: 3325 opt: 3325  Z-score: 2869.0  bits: 540.6 E(85289): 4.6e-153
Smith-Waterman score: 3325; 100.0% identity (100.0% similar) in 503 aa overlap (75-577:1-503)

           50        60        70        80        90       100    
pF1KSD CVCGHLLQDPIAPTNSTCQHYVCKTCKGKKMMMKPSCSWCKDYEQFEENKQLSILVNCYK
                                     ::::::::::::::::::::::::::::::
XP_005                               MMMKPSCSWCKDYEQFEENKQLSILVNCYK
                                             10        20        30

          110       120       130       140       150       160    
pF1KSD KLCEYITQTTLARDIIEAVDCSSDILALLNDGSLFCEETEKPSDSSFTLCLTHSPLPSTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KLCEYITQTTLARDIIEAVDCSSDILALLNDGSLFCEETEKPSDSSFTLCLTHSPLPSTS
               40        50        60        70        80        90

          170       180       190       200       210       220    
pF1KSD EPTTDPQASLSPMSESTLSIAIGSSVINGLPTYNGLSIDRFGINIPSPEHSNTIDVCNTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EPTTDPQASLSPMSESTLSIAIGSSVINGLPTYNGLSIDRFGINIPSPEHSNTIDVCNTV
              100       110       120       130       140       150

          230       240       250       260       270       280    
pF1KSD DIKTEDLSDSLPPVCDTVATDLCSTGIDICSFSEDIKPGDSLLLSVEEVLRSLETVSNTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DIKTEDLSDSLPPVCDTVATDLCSTGIDICSFSEDIKPGDSLLLSVEEVLRSLETVSNTE
              160       170       180       190       200       210

          290       300       310       320       330       340    
pF1KSD VCCPNLQPNLEATVSNGPFLQLSSQSLSHNVFMSTSPALHGLSCTAATPKIAKLNRKRSR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VCCPNLQPNLEATVSNGPFLQLSSQSLSHNVFMSTSPALHGLSCTAATPKIAKLNRKRSR
              220       230       240       250       260       270

          350       360       370       380       390       400    
pF1KSD SESDSEKVQPLPISTIIRGPTLGASAPVTVKRESKISLQPIATVPNGGTTPKISKTVLLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SESDSEKVQPLPISTIIRGPTLGASAPVTVKRESKISLQPIATVPNGGTTPKISKTVLLS
              280       290       300       310       320       330

          410       420       430       440       450       460    
pF1KSD TKSMKKSHEHGSKKSHSKTKPGILKKDKAVKEKIPSHHFMPGSPTKTVYKKPQEKKGCKC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TKSMKKSHEHGSKKSHSKTKPGILKKDKAVKEKIPSHHFMPGSPTKTVYKKPQEKKGCKC
              340       350       360       370       380       390

          470       480       490       500       510       520    
pF1KSD GRATQNPSVLTCRGQRCPCYSNRKACLDCICRGCQNSYMANGEKKLEAFAVPEKALEQTR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GRATQNPSVLTCRGQRCPCYSNRKACLDCICRGCQNSYMANGEKKLEAFAVPEKALEQTR
              400       410       420       430       440       450

          530       540       550       560       570       
pF1KSD LTLGINVTSIAVRNASTSTSVINVTGSPVTTFLAASTHDDKSLDEAIDMRFDC
       :::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LTLGINVTSIAVRNASTSTSVINVTGSPVTTFLAASTHDDKSLDEAIDMRFDC
              460       470       480       490       500   




577 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 06:43:58 2016 done: Thu Nov  3 06:43:59 2016
 Total Scan time: 10.500 Total Display time:  0.040

Function used was FASTA [36.3.4 Apr, 2011]
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