Result of FASTA (omim) for pF1KSDA1470
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KSDA1470, 522 aa
  1>>>pF1KSDA1470 522 - 522 aa - 522 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.0646+/-0.000381; mu= 10.6028+/- 0.024
 mean_var=123.8613+/-24.552, 0's: 0 Z-trim(117.0): 113  B-trim: 90 in 2/49
 Lambda= 0.115241
 statistics sampled from 28512 (28658) to 28512 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.676), E-opt: 0.2 (0.336), width:  16
 Scan time:  9.950

The best scores are:                                      opt bits E(85289)
NP_001129676 (OMIM: 609587) protein RCC2 [Homo sap ( 522) 3555 602.4 1.1e-171
NP_061185 (OMIM: 609587) protein RCC2 [Homo sapien ( 522) 3555 602.4 1.1e-171
NP_001041664 (OMIM: 179710) regulator of chromosom ( 421)  394 76.8 1.4e-13
NP_001260 (OMIM: 179710) regulator of chromosome c ( 421)  394 76.8 1.4e-13
NP_001041660 (OMIM: 179710) regulator of chromosom ( 438)  394 76.8 1.5e-13
NP_001041659 (OMIM: 179710) regulator of chromosom ( 452)  394 76.8 1.5e-13
XP_016875863 (OMIM: 603524) PREDICTED: RCC1 and BT ( 340)  359 70.9 6.8e-12
XP_016875864 (OMIM: 603524) PREDICTED: RCC1 and BT ( 340)  359 70.9 6.8e-12
XP_016875865 (OMIM: 603524) PREDICTED: RCC1 and BT ( 324)  358 70.7 7.3e-12
NP_003913 (OMIM: 605109,617011) probable E3 ubiqui (4861)  365 72.6   3e-11
XP_016878194 (OMIM: 605109,617011) PREDICTED: prob (4883)  365 72.6   3e-11
XP_016878193 (OMIM: 605109,617011) PREDICTED: prob (4885)  365 72.6   3e-11
XP_016878192 (OMIM: 605109,617011) PREDICTED: prob (4891)  365 72.6   3e-11
XP_016878190 (OMIM: 605109,617011) PREDICTED: prob (4892)  365 72.6   3e-11
XP_016878191 (OMIM: 605109,617011) PREDICTED: prob (4892)  365 72.6   3e-11
XP_016878189 (OMIM: 605109,617011) PREDICTED: prob (4897)  365 72.6   3e-11
XP_016878188 (OMIM: 605109,617011) PREDICTED: prob (4909)  365 72.6   3e-11
NP_001305434 (OMIM: 605200) probable E3 ubiquitin- ( 368)  346 68.8 3.2e-11
XP_005263389 (OMIM: 605200) PREDICTED: probable E3 ( 896)  346 69.0 6.7e-11
XP_005263388 (OMIM: 605200) PREDICTED: probable E3 ( 903)  346 69.0 6.7e-11
XP_016864296 (OMIM: 605200) PREDICTED: probable E3 ( 924)  346 69.0 6.8e-11
NP_001258531 (OMIM: 605200) probable E3 ubiquitin- ( 932)  346 69.0 6.9e-11
XP_005263387 (OMIM: 605200) PREDICTED: probable E3 ( 993)  346 69.0 7.3e-11
XP_005263386 (OMIM: 605200) PREDICTED: probable E3 (1042)  346 69.1 7.5e-11
XP_016864295 (OMIM: 605200) PREDICTED: probable E3 (1042)  346 69.1 7.5e-11
XP_005263384 (OMIM: 605200) PREDICTED: probable E3 (1050)  346 69.1 7.6e-11
NP_055421 (OMIM: 605200) probable E3 ubiquitin-pro (1050)  346 69.1 7.6e-11
XP_016871530 (OMIM: 609248) PREDICTED: probable E3 ( 936)  334 67.0 2.8e-10
XP_011537899 (OMIM: 609248) PREDICTED: probable E3 ( 960)  334 67.0 2.8e-10
NP_001265114 (OMIM: 609248) probable E3 ubiquitin- ( 979)  334 67.0 2.9e-10
XP_011537898 (OMIM: 609248) PREDICTED: probable E3 ( 987)  334 67.1 2.9e-10
XP_011537896 (OMIM: 609248) PREDICTED: probable E3 (1011)  334 67.1 2.9e-10
XP_011537897 (OMIM: 609248) PREDICTED: probable E3 (1011)  334 67.1 2.9e-10
NP_056416 (OMIM: 609248) probable E3 ubiquitin-pro (1049)  334 67.1   3e-10
NP_071362 (OMIM: 609248) probable E3 ubiquitin-pro (1057)  334 67.1   3e-10
XP_011537895 (OMIM: 609248) PREDICTED: probable E3 (1073)  334 67.1 3.1e-10
XP_011537894 (OMIM: 609248) PREDICTED: probable E3 (1081)  334 67.1 3.1e-10
NP_057407 (OMIM: 608242) E3 ISG15--protein ligase  (1024)  330 66.4 4.7e-10
XP_011530324 (OMIM: 608242) PREDICTED: E3 ISG15--p (1100)  330 66.4   5e-10
NP_001158608 (OMIM: 609249) probable E3 ubiquitin- ( 986)  296 60.7 2.3e-08
NP_060382 (OMIM: 609249) probable E3 ubiquitin-pro (1022)  296 60.7 2.4e-08
NP_835464 (OMIM: 609799,613824,615415) serine/thre ( 692)  292 60.0 2.7e-08
XP_011522942 (OMIM: 609799,613824,615415) PREDICTE ( 716)  292 60.0 2.8e-08
XP_011530355 (OMIM: 609249) PREDICTED: probable E3 ( 998)  291 59.9 4.1e-08
XP_005263140 (OMIM: 609249) PREDICTED: probable E3 (1034)  291 59.9 4.2e-08
XP_016879989 (OMIM: 609799,613824,615415) PREDICTE ( 666)  285 58.8 5.9e-08
XP_016879988 (OMIM: 609799,613824,615415) PREDICTE ( 705)  285 58.8 6.2e-08
XP_011522940 (OMIM: 609799,613824,615415) PREDICTE ( 729)  285 58.8 6.4e-08
XP_005268266 (OMIM: 609798,614262,617022,617025) P ( 873)  285 58.9 7.4e-08
NP_001316166 (OMIM: 609798,614262,617022,617025) s ( 991)  285 58.9 8.2e-08


>>NP_001129676 (OMIM: 609587) protein RCC2 [Homo sapiens  (522 aa)
 initn: 3555 init1: 3555 opt: 3555  Z-score: 3203.5  bits: 602.4 E(85289): 1.1e-171
Smith-Waterman score: 3555; 100.0% identity (100.0% similar) in 522 aa overlap (1-522:1-522)

               10        20        30        40        50        60
pF1KSD MPRKKAAAAAWEEPSSGNGTARAGPRKRGGPAGRKRERPERCSSSSGGGSSGDEDGLELD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPRKKAAAAAWEEPSSGNGTARAGPRKRGGPAGRKRERPERCSSSSGGGSSGDEDGLELD
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD GAPGGGKRAARPATAGKAGGAAVVITEPEHTKERVKLEGSKCKGQLLIFGATNWDLIGRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAPGGGKRAARPATAGKAGGAAVVITEPEHTKERVKLEGSKCKGQLLIFGATNWDLIGRK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD EVPKQQAAYRNLGQNLWGPHRYGCLAGVRVRTVVSGSCAAHSLLITTEGKLWSWGRNEKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVPKQQAAYRNLGQNLWGPHRYGCLAGVRVRTVVSGSCAAHSLLITTEGKLWSWGRNEKG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD QLGHGDTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTETGSVFAFGENKMGQLGLGNQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLGHGDTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTETGSVFAFGENKMGQLGLGNQT
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD DAVPSPAQIMYNGQPITKMACGAEFSMIMDCKGNLYSFGCPEYGQLGHNSDGKFIARAQR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DAVPSPAQIMYNGQPITKMACGAEFSMIMDCKGNLYSFGCPEYGQLGHNSDGKFIARAQR
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD IEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVACGANHTLVLDSQKRVFSWGFGGYG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVACGANHTLVLDSQKRVFSWGFGGYG
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD RLGHAEQKDEMVPRLVKLFDFPGRGASQIYAGYTCSFAVSEVGGLFFWGATNTSRESTMY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLGHAEQKDEMVPRLVKLFDFPGRGASQIYAGYTCSFAVSEVGGLFFWGATNTSRESTMY
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD PKAVQDLCGWRIRSLACGKSSIIVAADESTISWGPSPTFGELGYGDHKPKSSTAAQEVKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKAVQDLCGWRIRSLACGKSSIIVAADESTISWGPSPTFGELGYGDHKPKSSTAAQEVKT
              430       440       450       460       470       480

              490       500       510       520  
pF1KSD LDGIFSEQVAMGYSHSLVIARDESETEKEKIKKLPEYNPRTL
       ::::::::::::::::::::::::::::::::::::::::::
NP_001 LDGIFSEQVAMGYSHSLVIARDESETEKEKIKKLPEYNPRTL
              490       500       510       520  

>>NP_061185 (OMIM: 609587) protein RCC2 [Homo sapiens]    (522 aa)
 initn: 3555 init1: 3555 opt: 3555  Z-score: 3203.5  bits: 602.4 E(85289): 1.1e-171
Smith-Waterman score: 3555; 100.0% identity (100.0% similar) in 522 aa overlap (1-522:1-522)

               10        20        30        40        50        60
pF1KSD MPRKKAAAAAWEEPSSGNGTARAGPRKRGGPAGRKRERPERCSSSSGGGSSGDEDGLELD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 MPRKKAAAAAWEEPSSGNGTARAGPRKRGGPAGRKRERPERCSSSSGGGSSGDEDGLELD
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD GAPGGGKRAARPATAGKAGGAAVVITEPEHTKERVKLEGSKCKGQLLIFGATNWDLIGRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 GAPGGGKRAARPATAGKAGGAAVVITEPEHTKERVKLEGSKCKGQLLIFGATNWDLIGRK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD EVPKQQAAYRNLGQNLWGPHRYGCLAGVRVRTVVSGSCAAHSLLITTEGKLWSWGRNEKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 EVPKQQAAYRNLGQNLWGPHRYGCLAGVRVRTVVSGSCAAHSLLITTEGKLWSWGRNEKG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD QLGHGDTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTETGSVFAFGENKMGQLGLGNQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 QLGHGDTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTETGSVFAFGENKMGQLGLGNQT
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD DAVPSPAQIMYNGQPITKMACGAEFSMIMDCKGNLYSFGCPEYGQLGHNSDGKFIARAQR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 DAVPSPAQIMYNGQPITKMACGAEFSMIMDCKGNLYSFGCPEYGQLGHNSDGKFIARAQR
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD IEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVACGANHTLVLDSQKRVFSWGFGGYG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 IEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVACGANHTLVLDSQKRVFSWGFGGYG
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD RLGHAEQKDEMVPRLVKLFDFPGRGASQIYAGYTCSFAVSEVGGLFFWGATNTSRESTMY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 RLGHAEQKDEMVPRLVKLFDFPGRGASQIYAGYTCSFAVSEVGGLFFWGATNTSRESTMY
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD PKAVQDLCGWRIRSLACGKSSIIVAADESTISWGPSPTFGELGYGDHKPKSSTAAQEVKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 PKAVQDLCGWRIRSLACGKSSIIVAADESTISWGPSPTFGELGYGDHKPKSSTAAQEVKT
              430       440       450       460       470       480

              490       500       510       520  
pF1KSD LDGIFSEQVAMGYSHSLVIARDESETEKEKIKKLPEYNPRTL
       ::::::::::::::::::::::::::::::::::::::::::
NP_061 LDGIFSEQVAMGYSHSLVIARDESETEKEKIKKLPEYNPRTL
              490       500       510       520  

>>NP_001041664 (OMIM: 179710) regulator of chromosome co  (421 aa)
 initn: 347 init1: 111 opt: 394  Z-score: 364.6  bits: 76.8 E(85289): 1.4e-13
Smith-Waterman score: 394; 24.8% identity (58.1% similar) in 387 aa overlap (132-506:50-421)

             110       120       130       140       150       160 
pF1KSD CKGQLLIFGATNWDLIGRKEVPKQQAAYRNLGQNLWGPHRYGCLAGVRVRTVVSGSCAAH
                                     ::.:.   ..   :...   .: . . . :
NP_001 SKKVKVSHRSHSTEPGLVLTLGQGDVGQLGLGENVM-ERKKPALVSIPEDVVQAEAGGMH
      20        30        40        50         60        70        

             170       180       190       200         210         
pF1KSD SLLITTEGKLWSWGRNEKGQLGHGDTKRVEAPRLIEGLS--HEVIVSAACGRNHTLALTE
       .. ..  :...:.: :..: ::. ::. ::. ... :    .: .:... : .:: :::.
NP_001 TVCLSKSGQVYSFGCNDEGALGR-DTS-VEGSEMVPGKVELQEKVVQVSAGDSHTAALTD
       80        90       100         110       120       130      

     220         230       240       250       260       270       
pF1KSD TGSVFAFG--ENKMGQLGLGNQTDAVPSPAQIMYNGQPITKMACGAEFSMIMDCKGNLYS
        : :: .:  ... : .:: .       :.:.. .  :..:.: : .  ...   :.::.
NP_001 DGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQLD-VPVVKVASGNDHLVMLTADGDLYT
        140       150       160       170        180       190     

       280       290       300       310       320       330       
pF1KSD FGCPEYGQLGHNSDGKFIARAQRIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVAC
       .:: : ::::.  .  :  :. :   .  :::. : .   :.. ..     .:  .:. :
NP_001 LGCGEQGQLGRVPE-LFANRGGRQGLERLLVPKCVML---KSRGSR----GHVRFQDAFC
         200        210       220       230              240       

       340       350       360       370       380       390       
pF1KSD GANHTLVLDSQKRVFSWGFGGYGRLGHAEQKDEMVPRLVKLFDFPGRGASQIYAGYTCSF
       ::  :.... . .:...:...: .::    .. ..:. .  :    ..   . .:   . 
NP_001 GAYFTFAISHEGHVYGFGLSNYHQLGTPGTESCFIPQNLTSFKNSTKSWVGFSGGQHHTV
       250       260       270       280       290       300       

       400       410              420       430       440          
pF1KSD AVSEVGGLFFWGATNTSR-------ESTMYPKAVQDLCGWRIRSLACGKS-SIIVAADES
        ..  :  .  : .. .:       :    :  .. : .  . :.::: : .  :. :  
NP_001 CMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVGYAVTKDGR
       310       320       330       340         350       360     

     450       460       470       480       490       500         
pF1KSD TISWGPSPTFGELGYGDHKPKSSTAAQEVKTLDGIFSEQVAMGYSHSLVIARDESETEKE
       ...:: . .. .:: :. .   : . .  : :..    .:. : .:......:. ..   
NP_001 VFAWGMGTNY-QLGTGQDEDAWSPVEMMGKQLENRVVLSVSSGGQHTVLLVKDKEQS   
         370        380       390       400       410       420    

     510       520  
pF1KSD KIKKLPEYNPRTL

>>NP_001260 (OMIM: 179710) regulator of chromosome conde  (421 aa)
 initn: 347 init1: 111 opt: 394  Z-score: 364.6  bits: 76.8 E(85289): 1.4e-13
Smith-Waterman score: 394; 24.8% identity (58.1% similar) in 387 aa overlap (132-506:50-421)

             110       120       130       140       150       160 
pF1KSD CKGQLLIFGATNWDLIGRKEVPKQQAAYRNLGQNLWGPHRYGCLAGVRVRTVVSGSCAAH
                                     ::.:.   ..   :...   .: . . . :
NP_001 SKKVKVSHRSHSTEPGLVLTLGQGDVGQLGLGENVM-ERKKPALVSIPEDVVQAEAGGMH
      20        30        40        50         60        70        

             170       180       190       200         210         
pF1KSD SLLITTEGKLWSWGRNEKGQLGHGDTKRVEAPRLIEGLS--HEVIVSAACGRNHTLALTE
       .. ..  :...:.: :..: ::. ::. ::. ... :    .: .:... : .:: :::.
NP_001 TVCLSKSGQVYSFGCNDEGALGR-DTS-VEGSEMVPGKVELQEKVVQVSAGDSHTAALTD
       80        90       100         110       120       130      

     220         230       240       250       260       270       
pF1KSD TGSVFAFG--ENKMGQLGLGNQTDAVPSPAQIMYNGQPITKMACGAEFSMIMDCKGNLYS
        : :: .:  ... : .:: .       :.:.. .  :..:.: : .  ...   :.::.
NP_001 DGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQLD-VPVVKVASGNDHLVMLTADGDLYT
        140       150       160       170        180       190     

       280       290       300       310       320       330       
pF1KSD FGCPEYGQLGHNSDGKFIARAQRIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVAC
       .:: : ::::.  .  :  :. :   .  :::. : .   :.. ..     .:  .:. :
NP_001 LGCGEQGQLGRVPE-LFANRGGRQGLERLLVPKCVML---KSRGSR----GHVRFQDAFC
         200        210       220       230              240       

       340       350       360       370       380       390       
pF1KSD GANHTLVLDSQKRVFSWGFGGYGRLGHAEQKDEMVPRLVKLFDFPGRGASQIYAGYTCSF
       ::  :.... . .:...:...: .::    .. ..:. .  :    ..   . .:   . 
NP_001 GAYFTFAISHEGHVYGFGLSNYHQLGTPGTESCFIPQNLTSFKNSTKSWVGFSGGQHHTV
       250       260       270       280       290       300       

       400       410              420       430       440          
pF1KSD AVSEVGGLFFWGATNTSR-------ESTMYPKAVQDLCGWRIRSLACGKS-SIIVAADES
        ..  :  .  : .. .:       :    :  .. : .  . :.::: : .  :. :  
NP_001 CMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVGYAVTKDGR
       310       320       330       340         350       360     

     450       460       470       480       490       500         
pF1KSD TISWGPSPTFGELGYGDHKPKSSTAAQEVKTLDGIFSEQVAMGYSHSLVIARDESETEKE
       ...:: . .. .:: :. .   : . .  : :..    .:. : .:......:. ..   
NP_001 VFAWGMGTNY-QLGTGQDEDAWSPVEMMGKQLENRVVLSVSSGGQHTVLLVKDKEQS   
         370        380       390       400       410       420    

     510       520  
pF1KSD KIKKLPEYNPRTL

>>NP_001041660 (OMIM: 179710) regulator of chromosome co  (438 aa)
 initn: 347 init1: 111 opt: 394  Z-score: 364.4  bits: 76.8 E(85289): 1.5e-13
Smith-Waterman score: 394; 24.8% identity (58.1% similar) in 387 aa overlap (132-506:67-438)

             110       120       130       140       150       160 
pF1KSD CKGQLLIFGATNWDLIGRKEVPKQQAAYRNLGQNLWGPHRYGCLAGVRVRTVVSGSCAAH
                                     ::.:.   ..   :...   .: . . . :
NP_001 ARSCQVSHRSHSTEPGLVLTLGQGDVGQLGLGENVM-ERKKPALVSIPEDVVQAEAGGMH
         40        50        60        70         80        90     

             170       180       190       200         210         
pF1KSD SLLITTEGKLWSWGRNEKGQLGHGDTKRVEAPRLIEGLS--HEVIVSAACGRNHTLALTE
       .. ..  :...:.: :..: ::. ::. ::. ... :    .: .:... : .:: :::.
NP_001 TVCLSKSGQVYSFGCNDEGALGR-DTS-VEGSEMVPGKVELQEKVVQVSAGDSHTAALTD
         100       110        120        130       140       150   

     220         230       240       250       260       270       
pF1KSD TGSVFAFG--ENKMGQLGLGNQTDAVPSPAQIMYNGQPITKMACGAEFSMIMDCKGNLYS
        : :: .:  ... : .:: .       :.:.. .  :..:.: : .  ...   :.::.
NP_001 DGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQLD-VPVVKVASGNDHLVMLTADGDLYT
           160       170       180        190       200       210  

       280       290       300       310       320       330       
pF1KSD FGCPEYGQLGHNSDGKFIARAQRIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVAC
       .:: : ::::.  .  :  :. :   .  :::. : .   :.. ..     .:  .:. :
NP_001 LGCGEQGQLGRVPE-LFANRGGRQGLERLLVPKCVML---KSRGSR----GHVRFQDAFC
            220        230       240          250           260    

       340       350       360       370       380       390       
pF1KSD GANHTLVLDSQKRVFSWGFGGYGRLGHAEQKDEMVPRLVKLFDFPGRGASQIYAGYTCSF
       ::  :.... . .:...:...: .::    .. ..:. .  :    ..   . .:   . 
NP_001 GAYFTFAISHEGHVYGFGLSNYHQLGTPGTESCFIPQNLTSFKNSTKSWVGFSGGQHHTV
          270       280       290       300       310       320    

       400       410              420       430       440          
pF1KSD AVSEVGGLFFWGATNTSR-------ESTMYPKAVQDLCGWRIRSLACGKS-SIIVAADES
        ..  :  .  : .. .:       :    :  .. : .  . :.::: : .  :. :  
NP_001 CMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVGYAVTKDGR
          330       340       350       360         370       380  

     450       460       470       480       490       500         
pF1KSD TISWGPSPTFGELGYGDHKPKSSTAAQEVKTLDGIFSEQVAMGYSHSLVIARDESETEKE
       ...:: . .. .:: :. .   : . .  : :..    .:. : .:......:. ..   
NP_001 VFAWGMGTNY-QLGTGQDEDAWSPVEMMGKQLENRVVLSVSSGGQHTVLLVKDKEQS   
            390        400       410       420       430           

     510       520  
pF1KSD KIKKLPEYNPRTL

>>NP_001041659 (OMIM: 179710) regulator of chromosome co  (452 aa)
 initn: 347 init1: 111 opt: 394  Z-score: 364.2  bits: 76.8 E(85289): 1.5e-13
Smith-Waterman score: 394; 24.8% identity (58.1% similar) in 387 aa overlap (132-506:81-452)

             110       120       130       140       150       160 
pF1KSD CKGQLLIFGATNWDLIGRKEVPKQQAAYRNLGQNLWGPHRYGCLAGVRVRTVVSGSCAAH
                                     ::.:.   ..   :...   .: . . . :
NP_001 QKTRPVSHRSHSTEPGLVLTLGQGDVGQLGLGENVM-ERKKPALVSIPEDVVQAEAGGMH
               60        70        80         90       100         

             170       180       190       200         210         
pF1KSD SLLITTEGKLWSWGRNEKGQLGHGDTKRVEAPRLIEGLS--HEVIVSAACGRNHTLALTE
       .. ..  :...:.: :..: ::. ::. ::. ... :    .: .:... : .:: :::.
NP_001 TVCLSKSGQVYSFGCNDEGALGR-DTS-VEGSEMVPGKVELQEKVVQVSAGDSHTAALTD
     110       120       130         140       150       160       

     220         230       240       250       260       270       
pF1KSD TGSVFAFG--ENKMGQLGLGNQTDAVPSPAQIMYNGQPITKMACGAEFSMIMDCKGNLYS
        : :: .:  ... : .:: .       :.:.. .  :..:.: : .  ...   :.::.
NP_001 DGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQLD-VPVVKVASGNDHLVMLTADGDLYT
       170       180       190       200        210       220      

       280       290       300       310       320       330       
pF1KSD FGCPEYGQLGHNSDGKFIARAQRIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVAC
       .:: : ::::.  .  :  :. :   .  :::. : .   :.. ..     .:  .:. :
NP_001 LGCGEQGQLGRVPE-LFANRGGRQGLERLLVPKCVML---KSRGSR----GHVRFQDAFC
        230       240        250       260              270        

       340       350       360       370       380       390       
pF1KSD GANHTLVLDSQKRVFSWGFGGYGRLGHAEQKDEMVPRLVKLFDFPGRGASQIYAGYTCSF
       ::  :.... . .:...:...: .::    .. ..:. .  :    ..   . .:   . 
NP_001 GAYFTFAISHEGHVYGFGLSNYHQLGTPGTESCFIPQNLTSFKNSTKSWVGFSGGQHHTV
      280       290       300       310       320       330        

       400       410              420       430       440          
pF1KSD AVSEVGGLFFWGATNTSR-------ESTMYPKAVQDLCGWRIRSLACGKS-SIIVAADES
        ..  :  .  : .. .:       :    :  .. : .  . :.::: : .  :. :  
NP_001 CMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVGYAVTKDGR
      340       350       360       370         380       390      

     450       460       470       480       490       500         
pF1KSD TISWGPSPTFGELGYGDHKPKSSTAAQEVKTLDGIFSEQVAMGYSHSLVIARDESETEKE
       ...:: . .. .:: :. .   : . .  : :..    .:. : .:......:. ..   
NP_001 VFAWGMGTNY-QLGTGQDEDAWSPVEMMGKQLENRVVLSVSSGGQHTVLLVKDKEQS   
        400        410       420       430       440       450     

     510       520  
pF1KSD KIKKLPEYNPRTL

>>XP_016875863 (OMIM: 603524) PREDICTED: RCC1 and BTB do  (340 aa)
 initn: 514 init1: 213 opt: 359  Z-score: 334.5  bits: 70.9 E(85289): 6.8e-12
Smith-Waterman score: 394; 31.7% identity (60.1% similar) in 243 aa overlap (134-373:94-310)

           110       120       130       140       150       160   
pF1KSD GQLLIFGATNWDLIGRKEVPKQQAAYRNLGQNLWGPHRYGCLAGVRVRTVVSGSCAAHSL
                                     :.   :.:   : : ..  .  :: . : .
XP_016 AGNEVLYTTVNDEIFVLGTNCCGCLGLGDVQSTIEPRRLDSLNGKKIACLSYGS-GPHIV
            70        80        90       100       110        120  

           170       180       190        200       210       220  
pF1KSD LITTEGKLWSWGRNEKGQLGHGDTKRVEAP-RLIEGLSHEVIVSAACGRNHTLALTETGS
       : ::::....::.:  .:::.: :..  .: ..  .::.. .. .:::  :.:.::  : 
XP_016 LATTEGEVFTWGHNAYSQLGNGTTNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTSDGE
            130       140       150       160       170       180  

            230       240       250         260       270       280
pF1KSD VFAFGENKMGQLGLGNQTDAVPSPAQIM--YNGQPITKMACGAEFSMIMDCKGNLYSFGC
       :::.: :. ::.: :. ..  : : ..    ... .. .:::    : .   :..: .: 
XP_016 VFAWGYNNSGQVGSGSTVNQ-PIPRRVTGCLQNKVVVTIACGQMCCMAVVDTGEVYVWGY
            190       200        210       220       230       240 

              290       300       310       320       330       340
pF1KSD PEYGQLGHNSDGKFIARAQRIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVACGAN
          :::: ...:.            . .: ::: .             .. :. ::::  
XP_016 NGNGQLGLGNSGN------------QPTPCRVAAL------------QGIRVQRVACGYA
             250                   260                   270       

              350       360       370       380       390       400
pF1KSD HTLVLDSQKRVFSWGFGGYGRLGHAEQKDEMVPRLVKLFDFPGRGASQIYAGYTCSFAVS
       ::::: .. .:..:: ..::.:: ......  :                           
XP_016 HTLVLTDEGQVYAWGANSYGQLGTGNKSNQSYPTPVTVEKDRILSERSHCPCESSDENGV
       280       290       300       310       320       330       

              410       420       430       440       450       460
pF1KSD EVGGLFFWGATNTSRESTMYPKAVQDLCGWRIRSLACGKSSIIVAADESTISWGPSPTFG
                                                                   
XP_016 PRG                                                         
       340                                                         

>>XP_016875864 (OMIM: 603524) PREDICTED: RCC1 and BTB do  (340 aa)
 initn: 514 init1: 213 opt: 359  Z-score: 334.5  bits: 70.9 E(85289): 6.8e-12
Smith-Waterman score: 394; 31.7% identity (60.1% similar) in 243 aa overlap (134-373:94-310)

           110       120       130       140       150       160   
pF1KSD GQLLIFGATNWDLIGRKEVPKQQAAYRNLGQNLWGPHRYGCLAGVRVRTVVSGSCAAHSL
                                     :.   :.:   : : ..  .  :: . : .
XP_016 AGNEVLYTTVNDEIFVLGTNCCGCLGLGDVQSTIEPRRLDSLNGKKIACLSYGS-GPHIV
            70        80        90       100       110        120  

           170       180       190        200       210       220  
pF1KSD LITTEGKLWSWGRNEKGQLGHGDTKRVEAP-RLIEGLSHEVIVSAACGRNHTLALTETGS
       : ::::....::.:  .:::.: :..  .: ..  .::.. .. .:::  :.:.::  : 
XP_016 LATTEGEVFTWGHNAYSQLGNGTTNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTSDGE
            130       140       150       160       170       180  

            230       240       250         260       270       280
pF1KSD VFAFGENKMGQLGLGNQTDAVPSPAQIM--YNGQPITKMACGAEFSMIMDCKGNLYSFGC
       :::.: :. ::.: :. ..  : : ..    ... .. .:::    : .   :..: .: 
XP_016 VFAWGYNNSGQVGSGSTVNQ-PIPRRVTGCLQNKVVVTIACGQMCCMAVVDTGEVYVWGY
            190       200        210       220       230       240 

              290       300       310       320       330       340
pF1KSD PEYGQLGHNSDGKFIARAQRIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVACGAN
          :::: ...:.            . .: ::: .             .. :. ::::  
XP_016 NGNGQLGLGNSGN------------QPTPCRVAAL------------QGIRVQRVACGYA
             250                   260                   270       

              350       360       370       380       390       400
pF1KSD HTLVLDSQKRVFSWGFGGYGRLGHAEQKDEMVPRLVKLFDFPGRGASQIYAGYTCSFAVS
       ::::: .. .:..:: ..::.:: ......  :                           
XP_016 HTLVLTDEGQVYAWGANSYGQLGTGNKSNQSYPTPVTVEKDRILSERSHCPCESSDENGV
       280       290       300       310       320       330       

              410       420       430       440       450       460
pF1KSD EVGGLFFWGATNTSRESTMYPKAVQDLCGWRIRSLACGKSSIIVAADESTISWGPSPTFG
                                                                   
XP_016 PRG                                                         
       340                                                         

>>XP_016875865 (OMIM: 603524) PREDICTED: RCC1 and BTB do  (324 aa)
 initn: 514 init1: 213 opt: 358  Z-score: 334.0  bits: 70.7 E(85289): 7.3e-12
Smith-Waterman score: 394; 31.7% identity (60.1% similar) in 243 aa overlap (134-373:94-310)

           110       120       130       140       150       160   
pF1KSD GQLLIFGATNWDLIGRKEVPKQQAAYRNLGQNLWGPHRYGCLAGVRVRTVVSGSCAAHSL
                                     :.   :.:   : : ..  .  :: . : .
XP_016 AGNEVLYTTVNDEIFVLGTNCCGCLGLGDVQSTIEPRRLDSLNGKKIACLSYGS-GPHIV
            70        80        90       100       110        120  

           170       180       190        200       210       220  
pF1KSD LITTEGKLWSWGRNEKGQLGHGDTKRVEAP-RLIEGLSHEVIVSAACGRNHTLALTETGS
       : ::::....::.:  .:::.: :..  .: ..  .::.. .. .:::  :.:.::  : 
XP_016 LATTEGEVFTWGHNAYSQLGNGTTNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTSDGE
            130       140       150       160       170       180  

            230       240       250         260       270       280
pF1KSD VFAFGENKMGQLGLGNQTDAVPSPAQIM--YNGQPITKMACGAEFSMIMDCKGNLYSFGC
       :::.: :. ::.: :. ..  : : ..    ... .. .:::    : .   :..: .: 
XP_016 VFAWGYNNSGQVGSGSTVNQ-PIPRRVTGCLQNKVVVTIACGQMCCMAVVDTGEVYVWGY
            190       200        210       220       230       240 

              290       300       310       320       330       340
pF1KSD PEYGQLGHNSDGKFIARAQRIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVACGAN
          :::: ...:.            . .: ::: .             .. :. ::::  
XP_016 NGNGQLGLGNSGN------------QPTPCRVAAL------------QGIRVQRVACGYA
             250                   260                   270       

              350       360       370       380       390       400
pF1KSD HTLVLDSQKRVFSWGFGGYGRLGHAEQKDEMVPRLVKLFDFPGRGASQIYAGYTCSFAVS
       ::::: .. .:..:: ..::.:: ......  :                           
XP_016 HTLVLTDEGQVYAWGANSYGQLGTGNKSNQSYPTPVTVEKDRVCGQN             
       280       290       300       310       320                 

              410       420       430       440       450       460
pF1KSD EVGGLFFWGATNTSRESTMYPKAVQDLCGWRIRSLACGKSSIIVAADESTISWGPSPTFG

>>NP_003913 (OMIM: 605109,617011) probable E3 ubiquitin-  (4861 aa)
 initn: 431 init1: 286 opt: 365  Z-score: 323.1  bits: 72.6 E(85289): 3e-11
Smith-Waterman score: 456; 33.0% identity (60.8% similar) in 288 aa overlap (145-398:4076-4357)

          120       130       140       150       160         170  
pF1KSD DLIGRKEVPKQQAAYRNLGQNLWGPHRYGCLAGVRVRTVVSGSCAA--HSLLITTEGKLW
                                     : :  :  .:. ::..  ::. .:  :...
NP_003 GTVLACGEGSYGRLGQGNSDDLHVLTVISALQGFVVTQLVT-SCGSDGHSMALTESGEVF
        4050      4060      4070      4080       4090      4100    

            180       190       200       210       220       230  
pF1KSD SWGRNEKGQLGHGDTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTETGSVFAFGENKMG
       ::: .. :.::::.. : . :: ::.:. : .:. .:: .:. ..:  :..:.::.. .:
NP_003 SWGDGDYGKLGHGNSDRQRRPRQIEALQGEEVVQMSCGFKHSAVVTSDGKLFTFGNGDYG
         4110      4120      4130      4140      4150      4160    

            240       250        260       270        280          
pF1KSD QLGLGNQTDAVPSPAQIM-YNGQPITKMACGAEFSMIMDCKGNL-YSFGCPEYGQLG-HN
       .::::: ..    : ..   .:  : ..::: . .. ..  :.. ..::  .::.::  :
NP_003 RLGLGNTSNK-KLPERVTALEGYQIGQVACGLNHTLAVSADGSMVWAFGDGDYGKLGLGN
         4170       4180      4190      4200      4210      4220   

     290       300       310           320                         
pF1KSD SDGKFIARAQRIEYDCELVPRRVA----IFIEKTKDGQI----------LP---------
       : .:  .  :.:.  : .  ..::    . .  ::::..          ::         
NP_003 STAK--SSPQKIDVLCGIGIKKVACGTQFSVALTKDGHVYTFGQDRLIGLPEGRARNHNR
            4230      4240      4250      4260      4270      4280 

              330       340       350       360       370       380
pF1KSD ---VP---NVVVRDVACGANHTLVLDSQKRVFSWGFGGYGRLGHAEQKDEMVPRLVKLFD
          .:   .:...::: ::.:::.: :.  :..:: .. :.:: .. .    : ::    
NP_003 PQQIPVLAGVIIEDVAVGAEHTLALASNGDVYAWGSNSEGQLGLGHTNHVREPTLVT--G
            4290      4300      4310      4320      4330           

              390       400       410       420       430       440
pF1KSD FPGRGASQIYAGYTCSFAVSEVGGLFFWGATNTSRESTMYPKAVQDLCGWRIRSLACGKS
       . :... :: ::   : :                                          
NP_003 LQGKNVRQISAGRCHSAAWTAPPVPPRAPGVSVPLQLGLPDTVPPQYGALREVSIHTVRA
    4340      4350      4360      4370      4380      4390         

>--
 initn: 485 init1: 180 opt: 242  Z-score: 212.5  bits: 52.2 E(85289): 4.2e-05
Smith-Waterman score: 444; 28.6% identity (60.0% similar) in 360 aa overlap (151-497:406-731)

              130       140       150        160       170         
pF1KSD EVPKQQAAYRNLGQNLWGPHRYGCLAGVRVRTVVSGS-CAAHSLLITTEGKLWSWGRNEK
                                     .:. .:. :   ...:.:.:.. . :..  
NP_003 VWGSNSSHQLVEGTQEKILQPKLAPSFSDAQTIEAGQYC---TFVISTDGSVRACGKGSY
         380       390       400       410          420       430  

     180       190       200         210        220       230      
pF1KSD GQLGHGDTKRVEAPRLIEGLSHEVI--VSAACGRN-HTLALTETGSVFAFGENKMGQLGL
       :.:: ::..   . . .    :. :  ::.. : . ::::.:  : ::..:.. .:.:: 
NP_003 GRLGLGDSNNQSTLKKLTFEPHRSIKKVSSSKGSDGHTLAFTTEGEVFSWGDGDYGKLGH
            440       450       460       470       480       490  

         240       250       260       270       280       290     
pF1KSD GNQ-TDAVPSPAQIMYNGQPITKMACGAEFSMIMDCKGNLYSFGCPEYGQLGHNSDGKFI
       ::. :.  :.  :   .:. .. .. : . :  .   :.::..:  ..:.:::   :   
NP_003 GNSSTQKYPKLIQGPLQGKVVVCVSAGYRHSAAVTEDGELYTWGEGDFGRLGH---GDSN
            500       510       520       530       540            

         300       310       320       330       340       350     
pF1KSD ARAQRIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVACGANHTLVLDSQKRVFSWG
       .:          .:  :       ::     . :  : .:.::..::..:... :.  :.
NP_003 SRN---------IPTLV-------KD-----ISN--VGEVSCGSSHTIALSKDGRTV-WS
     550                            560         570       580      

           360       370       380       390       400             
pF1KSD FGG--YGRLGHAEQKDEMVPRLVKLFDFPGRGASQIYAGYTCSFAVSEVGGLFFWG----
       :::   :.:::.. .  . :.... ..  :    .. ::   :.:.. .: .. ::    
NP_003 FGGGDNGKLGHGDTNRVYKPKVIEALQ--GMFIRKVCAGSQSSLALTSTGQVYAWGCGAC
         590       600       610         620       630       640   

      410       420       430       440        450       460       
pF1KSD -ATNTSRESTMYPKAVQDLCGWRIRSLACGKSS-IIVAADESTISWGPSPTFGELGYGDH
        . ..:. ... :: ...: . :: ... : :  . .. :. . .:: . ..:. : :. 
NP_003 LGCGSSEATALRPKLIEELAATRIVDVSIGDSHCLALSHDNEVYAWG-NNSMGQCGQGN-
           650       660       670       680       690        700  

       470       480       490       500       510       520       
pF1KSD KPKSSTAAQEVKTLDGIFSEQVAMGYSHSLVIARDESETEKEKIKKLPEYNPRTL     
       .    :  ..:. ::::  .:.. : ::::                              
NP_003 STGPITKPKKVSGLDGIAIQQISAGTSHSLAWTALPRDRQVVAWHRPYCVDLEESTFSHL
             710       720       730       740       750       760 




522 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 06:24:32 2016 done: Thu Nov  3 06:24:33 2016
 Total Scan time:  9.950 Total Display time:  0.090

Function used was FASTA [36.3.4 Apr, 2011]
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