Result of FASTA (omim) for pF1KSDA1344
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KSDA1344, 825 aa
  1>>>pF1KSDA1344 825 - 825 aa - 825 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.3707+/-0.000471; mu= 20.3896+/- 0.030
 mean_var=68.2183+/-13.972, 0's: 0 Z-trim(108.6): 38  B-trim: 312 in 1/54
 Lambda= 0.155283
 statistics sampled from 16645 (16659) to 16645 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.533), E-opt: 0.2 (0.195), width:  16
 Scan time: 11.310

The best scores are:                                      opt bits E(85289)
NP_065835 (OMIM: 616179) thioredoxin domain-contai ( 825) 5350 1208.5       0
NP_001153519 (OMIM: 616179) thioredoxin domain-con ( 820) 5302 1197.7       0
XP_016876994 (OMIM: 616179) PREDICTED: thioredoxin ( 465) 2812 639.7 8.6e-183
NP_110437 (OMIM: 616412) thioredoxin domain-contai ( 432)  158 45.2 0.00077


>>NP_065835 (OMIM: 616179) thioredoxin domain-containing  (825 aa)
 initn: 5350 init1: 5350 opt: 5350  Z-score: 6471.8  bits: 1208.5 E(85289):    0
Smith-Waterman score: 5350; 99.8% identity (100.0% similar) in 825 aa overlap (1-825:1-825)

               10        20        30        40        50        60
pF1KSD MFSGFNVFRVGISFVIMCIFYMPTVNSLPELSPQKYFSTLQPGKASLAYFCQADSPRTSV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 MFSGFNVFRVGISFVIMCIFYMPTVNSLPELSPQKYFSTLQPGKASLAYFCQADSPRTSV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD FLEELNEAVRPLQDYGISVAKVNCVKEEISRYCGKEKDLMKAYLFKGNILLREFPTDTLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 FLEELNEAVRPLQDYGISVAKVNCVKEEISRYCGKEKDLMKAYLFKGNILLREFPTDTLF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD DVNAIVAHVLFALLFSEVKYITNLEDLQNIENALKGKANIIFSYVRAIGIPEHRAVMEAG
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
NP_065 DVNAIVAHVLFALLFSEVKYITNLEDLQNIENALKGKANIIFSYVRAIGIPEHRAVMEAA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD FVYGTTYQFVLTTEIALLESIGSEDVEYAHLYFFHCKLVLDLTQQCRRTLMEQPLTTLNI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 FVYGTTYQFVLTTEIALLESIGSEDVEYAHLYFFHCKLVLDLTQQCRRTLMEQPLTTLNI
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD HLFIKTMKAPLLTEVAEDPQQVSTVHLQLGLPLVFIVSQQATYEADRRTAEWVAWRLLGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 HLFIKTMKAPLLTEVAEDPQQVSTVHLQLGLPLVFIVSQQATYEADRRTAEWVAWRLLGK
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD AGVLLLLRDSLEVNIPQDANVVFKRAEEGVPVEFLVLHDVDLIISHVENNMHIEEIQEDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 AGVLLLLRDSLEVNIPQDANVVFKRAEEGVPVEFLVLHDVDLIISHVENNMHIEEIQEDE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD DNDMEGPDIDVQDDEVAETVFRDRKRKLPLELTVELTEETFNATVMASDSIVLFYAGWQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 DNDMEGPDIDVQDDEVAETVFRDRKRKLPLELTVELTEETFNATVMASDSIVLFYAGWQA
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD VSMAFLQSYIDVAVKLKGTSTMLLTRINCADWSDVCTKQNVTEFPIIKMYKKGENPVSYA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 VSMAFLQSYIDVAVKLKGTSTMLLTRINCADWSDVCTKQNVTEFPIIKMYKKGENPVSYA
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD GMLGTKDLLKFIQLNRISYPVNITSIQEAEEYLSGELYKDLILYSSVSVLGLFSPTMKTA
       :::::.::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 GMLGTEDLLKFIQLNRISYPVNITSIQEAEEYLSGELYKDLILYSSVSVLGLFSPTMKTA
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD KEDFSEAGNYLKGYVITGIYSEEDVLLLSTKYAASLPALLLARHTEGKIESIPLASTHAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 KEDFSEAGNYLKGYVITGIYSEEDVLLLSTKYAASLPALLLARHTEGKIESIPLASTHAQ
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD DIVQIITDALLEMFPEITVENLPSYFRLQKPLLILFSDGTVNPQYKKAILTLVKQKYLDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 DIVQIITDALLEMFPEITVENLPSYFRLQKPLLILFSDGTVNPQYKKAILTLVKQKYLDS
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD FTPCWLNLKNTPVGRGILRAYFDPLPPLPLLVLVNLHSGGQVFAFPSDQAIIEENLVLWL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 FTPCWLNLKNTPVGRGILRAYFDPLPPLPLLVLVNLHSGGQVFAFPSDQAIIEENLVLWL
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD KKLEAGLENHITILPAQEWKPPLPAYDFLSMIDAATSQRGTRKVPKCMKETDVQENDKEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 KKLEAGLENHITILPAQEWKPPLPAYDFLSMIDAATSQRGTRKVPKCMKETDVQENDKEQ
              730       740       750       760       770       780

              790       800       810       820     
pF1KSD HEDKSAVRKEPIETLRIKHWNRSNWFKEAEKSFRRDKELGCSKVN
       :::::::::::::::::::::::::::::::::::::::::::::
NP_065 HEDKSAVRKEPIETLRIKHWNRSNWFKEAEKSFRRDKELGCSKVN
              790       800       810       820     

>>NP_001153519 (OMIM: 616179) thioredoxin domain-contain  (820 aa)
 initn: 4457 init1: 4457 opt: 5302  Z-score: 6413.7  bits: 1197.7 E(85289):    0
Smith-Waterman score: 5302; 99.2% identity (99.4% similar) in 825 aa overlap (1-825:1-820)

               10        20        30        40        50        60
pF1KSD MFSGFNVFRVGISFVIMCIFYMPTVNSLPELSPQKYFSTLQPGKASLAYFCQADSPRTSV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MFSGFNVFRVGISFVIMCIFYMPTVNSLPELSPQKYFSTLQPGKASLAYFCQADSPRTSV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD FLEELNEAVRPLQDYGISVAKVNCVKEEISRYCGKEKDLMKAYLFKGNILLREFPTDTLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLEELNEAVRPLQDYGISVAKVNCVKEEISRYCGKEKDLMKAYLFKGNILLREFPTDTLF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD DVNAIVAHVLFALLFSEVKYITNLEDLQNIENALKGKANIIFSYVRAIGIPEHRAVMEAG
       :::::::::::     :::::::::::::::::::::::::::::::::::::::::::.
NP_001 DVNAIVAHVLF-----EVKYITNLEDLQNIENALKGKANIIFSYVRAIGIPEHRAVMEAA
              130            140       150       160       170     

              190       200       210       220       230       240
pF1KSD FVYGTTYQFVLTTEIALLESIGSEDVEYAHLYFFHCKLVLDLTQQCRRTLMEQPLTTLNI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FVYGTTYQFVLTTEIALLESIGSEDVEYAHLYFFHCKLVLDLTQQCRRTLMEQPLTTLNI
         180       190       200       210       220       230     

              250       260       270       280       290       300
pF1KSD HLFIKTMKAPLLTEVAEDPQQVSTVHLQLGLPLVFIVSQQATYEADRRTAEWVAWRLLGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLFIKTMKAPLLTEVAEDPQQVSTVHLQLGLPLVFIVSQQATYEADRRTAEWVAWRLLGK
         240       250       260       270       280       290     

              310       320       330       340       350       360
pF1KSD AGVLLLLRDSLEVNIPQDANVVFKRAEEGVPVEFLVLHDVDLIISHVENNMHIEEIQEDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGVLLLLRDSLEVNIPQDANVVFKRAEEGVPVEFLVLHDVDLIISHVENNMHIEEIQEDE
         300       310       320       330       340       350     

              370       380       390       400       410       420
pF1KSD DNDMEGPDIDVQDDEVAETVFRDRKRKLPLELTVELTEETFNATVMASDSIVLFYAGWQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DNDMEGPDIDVQDDEVAETVFRDRKRKLPLELTVELTEETFNATVMASDSIVLFYAGWQA
         360       370       380       390       400       410     

              430       440       450       460       470       480
pF1KSD VSMAFLQSYIDVAVKLKGTSTMLLTRINCADWSDVCTKQNVTEFPIIKMYKKGENPVSYA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSMAFLQSYIDVAVKLKGTSTMLLTRINCADWSDVCTKQNVTEFPIIKMYKKGENPVSYA
         420       430       440       450       460       470     

              490       500       510       520       530       540
pF1KSD GMLGTKDLLKFIQLNRISYPVNITSIQEAEEYLSGELYKDLILYSSVSVLGLFSPTMKTA
       :::::.::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GMLGTEDLLKFIQLNRISYPVNITSIQEAEEYLSGELYKDLILYSSVSVLGLFSPTMKTA
         480       490       500       510       520       530     

              550       560       570       580       590       600
pF1KSD KEDFSEAGNYLKGYVITGIYSEEDVLLLSTKYAASLPALLLARHTEGKIESIPLASTHAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KEDFSEAGNYLKGYVITGIYSEEDVLLLSTKYAASLPALLLARHTEGKIESIPLASTHAQ
         540       550       560       570       580       590     

              610       620       630       640       650       660
pF1KSD DIVQIITDALLEMFPEITVENLPSYFRLQKPLLILFSDGTVNPQYKKAILTLVKQKYLDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DIVQIITDALLEMFPEITVENLPSYFRLQKPLLILFSDGTVNPQYKKAILTLVKQKYLDS
         600       610       620       630       640       650     

              670       680       690       700       710       720
pF1KSD FTPCWLNLKNTPVGRGILRAYFDPLPPLPLLVLVNLHSGGQVFAFPSDQAIIEENLVLWL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FTPCWLNLKNTPVGRGILRAYFDPLPPLPLLVLVNLHSGGQVFAFPSDQAIIEENLVLWL
         660       670       680       690       700       710     

              730       740       750       760       770       780
pF1KSD KKLEAGLENHITILPAQEWKPPLPAYDFLSMIDAATSQRGTRKVPKCMKETDVQENDKEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKLEAGLENHITILPAQEWKPPLPAYDFLSMIDAATSQRGTRKVPKCMKETDVQENDKEQ
         720       730       740       750       760       770     

              790       800       810       820     
pF1KSD HEDKSAVRKEPIETLRIKHWNRSNWFKEAEKSFRRDKELGCSKVN
       :::::::::::::::::::::::::::::::::::::::::::::
NP_001 HEDKSAVRKEPIETLRIKHWNRSNWFKEAEKSFRRDKELGCSKVN
         780       790       800       810       820

>>XP_016876994 (OMIM: 616179) PREDICTED: thioredoxin dom  (465 aa)
 initn: 2812 init1: 2812 opt: 2812  Z-score: 3402.7  bits: 639.7 E(85289): 8.6e-183
Smith-Waterman score: 2812; 99.8% identity (100.0% similar) in 437 aa overlap (1-437:1-437)

               10        20        30        40        50        60
pF1KSD MFSGFNVFRVGISFVIMCIFYMPTVNSLPELSPQKYFSTLQPGKASLAYFCQADSPRTSV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MFSGFNVFRVGISFVIMCIFYMPTVNSLPELSPQKYFSTLQPGKASLAYFCQADSPRTSV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD FLEELNEAVRPLQDYGISVAKVNCVKEEISRYCGKEKDLMKAYLFKGNILLREFPTDTLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLEELNEAVRPLQDYGISVAKVNCVKEEISRYCGKEKDLMKAYLFKGNILLREFPTDTLF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD DVNAIVAHVLFALLFSEVKYITNLEDLQNIENALKGKANIIFSYVRAIGIPEHRAVMEAG
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
XP_016 DVNAIVAHVLFALLFSEVKYITNLEDLQNIENALKGKANIIFSYVRAIGIPEHRAVMEAA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD FVYGTTYQFVLTTEIALLESIGSEDVEYAHLYFFHCKLVLDLTQQCRRTLMEQPLTTLNI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FVYGTTYQFVLTTEIALLESIGSEDVEYAHLYFFHCKLVLDLTQQCRRTLMEQPLTTLNI
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD HLFIKTMKAPLLTEVAEDPQQVSTVHLQLGLPLVFIVSQQATYEADRRTAEWVAWRLLGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HLFIKTMKAPLLTEVAEDPQQVSTVHLQLGLPLVFIVSQQATYEADRRTAEWVAWRLLGK
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD AGVLLLLRDSLEVNIPQDANVVFKRAEEGVPVEFLVLHDVDLIISHVENNMHIEEIQEDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGVLLLLRDSLEVNIPQDANVVFKRAEEGVPVEFLVLHDVDLIISHVENNMHIEEIQEDE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD DNDMEGPDIDVQDDEVAETVFRDRKRKLPLELTVELTEETFNATVMASDSIVLFYAGWQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DNDMEGPDIDVQDDEVAETVFRDRKRKLPLELTVELTEETFNATVMASDSIVLFYAGWQA
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD VSMAFLQSYIDVAVKLKGTSTMLLTRINCADWSDVCTKQNVTEFPIIKMYKKGENPVSYA
       :::::::::::::::::                                           
XP_016 VSMAFLQSYIDVAVKLKVVWGHLVCSLQHTWLAEKGRQSGHLGNV               
              430       440       450       460                    

>>NP_110437 (OMIM: 616412) thioredoxin domain-containing  (432 aa)
 initn: 176 init1: 102 opt: 158  Z-score: 189.9  bits: 45.2 E(85289): 0.00077
Smith-Waterman score: 158; 24.2% identity (57.6% similar) in 132 aa overlap (397-526:67-196)

        370       380       390       400       410       420      
pF1KSD PDIDVQDDEVAETVFRDRKRKLPLELTVELTEETFNATVMASDSIVLFYAGWQAVSMAFL
                                     : . :.  ....  .:.:.: : .  . . 
NP_110 RAQEAAAAAADGPPAADGEDGQDPHSKHLYTADMFTHGIQSAAHFVMFFAPWCGHCQRLQ
         40        50        60        70        80        90      

        430         440       450       460       470       480    
pF1KSD QSYIDVAVKLKGT--STMLLTRINCADWSDVCTKQNVTEFPIIKMYKKGENPVSYAGMLG
        .. :.. : ..   . . .....:.  ::::. :.:  .: .:..: :.. :.: :   
NP_110 PTWNDLGDKYNSMEDAKVYVAKVDCTAHSDVCSAQGVRGYPTLKLFKPGQEAVKYQGPRD
        100       110       120       130       140       150      

          490       500       510       520       530       540    
pF1KSD TKDLLKFIQLNRISYPVNITSIQEAEEYLSGELYKDLILYSSVSVLGLFSPTMKTAKEDF
        . : ...  .    ::  :   :.:   . :: . :   :.                  
NP_110 FQTLENWMLQTLNEEPV--TPEPEVEPPSAPELKQGLYELSASNFELHVAQGDHFIKFFA
        160       170         180       190       200       210    

          550       560       570       580       590       600    
pF1KSD SEAGNYLKGYVITGIYSEEDVLLLSTKYAASLPALLLARHTEGKIESIPLASTHAQDIVQ
                                                                   
NP_110 PWCGHCKALAPTWEQLALGLEHSETVKIGKVDCTQHYELCSGNQVRGYPTLLWFRDGKKV
          220       230       240       250       260       270    




825 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 05:54:02 2016 done: Thu Nov  3 05:54:03 2016
 Total Scan time: 11.310 Total Display time:  0.070

Function used was FASTA [36.3.4 Apr, 2011]
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