Result of FASTA (omim) for pF1KSDA1242
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KSDA1242, 493 aa
  1>>>pF1KSDA1242 493 - 493 aa - 493 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.0217+/-0.000492; mu= 10.0641+/- 0.030
 mean_var=168.1969+/-36.120, 0's: 0 Z-trim(114.3): 292  B-trim: 2116 in 2/48
 Lambda= 0.098893
 statistics sampled from 23635 (24082) to 23635 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.643), E-opt: 0.2 (0.282), width:  16
 Scan time: 10.290

The best scores are:                                      opt bits E(85289)
NP_057347 (OMIM: 603619) fizzy-related protein hom ( 493) 3300 483.7  5e-136
XP_005259630 (OMIM: 603619) PREDICTED: fizzy-relat ( 496) 3284 481.4 2.5e-135
NP_001129670 (OMIM: 603619) fizzy-related protein  ( 496) 3284 481.4 2.5e-135
XP_016882352 (OMIM: 603619) PREDICTED: fizzy-relat ( 528) 3284 481.5 2.6e-135
NP_001129669 (OMIM: 603619) fizzy-related protein  ( 404) 1856 277.6 4.6e-74
NP_001246 (OMIM: 603618) cell division cycle prote ( 499) 1094 169.0 2.8e-41
XP_016878353 (OMIM: 602703,616212) PREDICTED: kata ( 655)  320 58.7   6e-08
XP_016878352 (OMIM: 602703,616212) PREDICTED: kata ( 655)  320 58.7   6e-08
NP_005877 (OMIM: 602703,616212) katanin p80 WD40 r ( 655)  320 58.7   6e-08
XP_006721186 (OMIM: 602703,616212) PREDICTED: kata ( 658)  320 58.7   6e-08
XP_016878351 (OMIM: 602703,616212) PREDICTED: kata ( 672)  320 58.7 6.1e-08
XP_005255829 (OMIM: 602703,616212) PREDICTED: kata ( 672)  320 58.7 6.1e-08
XP_016878350 (OMIM: 602703,616212) PREDICTED: kata ( 672)  320 58.7 6.1e-08
XP_016878349 (OMIM: 602703,616212) PREDICTED: kata ( 675)  320 58.7 6.1e-08
XP_006721184 (OMIM: 602703,616212) PREDICTED: kata ( 675)  320 58.7 6.1e-08
XP_011521112 (OMIM: 602703,616212) PREDICTED: kata ( 675)  320 58.7 6.1e-08
XP_006721185 (OMIM: 602703,616212) PREDICTED: kata ( 675)  320 58.7 6.1e-08
XP_005247749 (OMIM: 610863,615185) PREDICTED: guan ( 340)  267 50.8 7.1e-06
NP_067642 (OMIM: 610863,615185) guanine nucleotide ( 340)  267 50.8 7.1e-06
XP_006713784 (OMIM: 610863,615185) PREDICTED: guan ( 340)  267 50.8 7.1e-06
NP_001308124 (OMIM: 270710,602342,608628,616944) F ( 427)  262 50.2 1.4e-05
XP_006713809 (OMIM: 270710,602342,608628,616944) P ( 514)  262 50.3 1.6e-05
NP_001308123 (OMIM: 270710,602342,608628,616944) F ( 514)  262 50.3 1.6e-05
XP_011511444 (OMIM: 270710,602342,608628,616944) P ( 514)  262 50.3 1.6e-05
XP_005247832 (OMIM: 270710,602342,608628,616944) P ( 514)  262 50.3 1.6e-05
NP_001308122 (OMIM: 270710,602342,608628,616944) F ( 514)  262 50.3 1.6e-05
XP_011511445 (OMIM: 270710,602342,608628,616944) P ( 514)  262 50.3 1.6e-05
XP_016862674 (OMIM: 270710,602342,608628,616944) P ( 514)  262 50.3 1.6e-05
NP_078941 (OMIM: 270710,602342,608628,616944) F-bo ( 514)  262 50.3 1.6e-05
XP_011511443 (OMIM: 270710,602342,608628,616944) P ( 514)  262 50.3 1.6e-05
XP_016885575 (OMIM: 400033) PREDICTED: F-box-like/ ( 577)  261 50.2 1.9e-05
NP_060058 (OMIM: 609012) WD repeat-containing prot ( 334)  257 49.4 1.9e-05
NP_438172 (OMIM: 609012) WD repeat-containing prot ( 334)  257 49.4 1.9e-05
XP_005272220 (OMIM: 609012) PREDICTED: WD repeat-c ( 334)  257 49.4 1.9e-05
XP_005267076 (OMIM: 215100,266500,601757,614879) P ( 285)  255 49.0 2.1e-05
NP_001284500 (OMIM: 139130,145500,617024) guanine  ( 339)  256 49.3 2.1e-05
NP_002066 (OMIM: 139130,145500,617024) guanine nuc ( 340)  256 49.3 2.1e-05
XP_016856550 (OMIM: 139380,613065,616973) PREDICTE ( 340)  256 49.3 2.1e-05
XP_016856548 (OMIM: 139380,613065,616973) PREDICTE ( 340)  256 49.3 2.1e-05
NP_002065 (OMIM: 139380,613065,616973) guanine nuc ( 340)  256 49.3 2.1e-05
NP_001269468 (OMIM: 139380,613065,616973) guanine  ( 340)  256 49.3 2.1e-05
XP_016856549 (OMIM: 139380,613065,616973) PREDICTE ( 340)  256 49.3 2.1e-05
XP_016885576 (OMIM: 400033) PREDICTED: F-box-like/ ( 540)  259 49.9 2.2e-05
NP_000279 (OMIM: 215100,266500,601757,614879) pero ( 323)  255 49.1 2.3e-05
NP_001269467 (OMIM: 139380,613065,616973) guanine  ( 240)  247 47.8 4.1e-05
NP_599021 (OMIM: 400033) F-box-like/WD repeat-cont ( 522)  252 48.9 4.2e-05
NP_599020 (OMIM: 400033) F-box-like/WD repeat-cont ( 522)  252 48.9 4.2e-05
NP_150600 (OMIM: 400033) F-box-like/WD repeat-cont ( 522)  252 48.9 4.2e-05
XP_005262629 (OMIM: 400033) PREDICTED: F-box-like/ ( 536)  252 48.9 4.3e-05
NP_005264 (OMIM: 139390) guanine nucleotide-bindin ( 340)  247 48.0 5.2e-05


>>NP_057347 (OMIM: 603619) fizzy-related protein homolog  (493 aa)
 initn: 3300 init1: 3300 opt: 3300  Z-score: 2563.0  bits: 483.7 E(85289): 5e-136
Smith-Waterman score: 3300; 100.0% identity (100.0% similar) in 493 aa overlap (1-493:1-493)

               10        20        30        40        50        60
pF1KSD MDQDYERRLLRQIVIQNENTMPRVTEMRRTLTPASSPVSSPSKHGDRFIPSRAGANWSVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MDQDYERRLLRQIVIQNENTMPRVTEMRRTLTPASSPVSSPSKHGDRFIPSRAGANWSVN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD FHRINENEKSPSQNRKAKDATSDNGKDGLAYSALLKNELLGAGIEKVQDPQTEDRRLQPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 FHRINENEKSPSQNRKAKDATSDNGKDGLAYSALLKNELLGAGIEKVQDPQTEDRRLQPS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD TPEKKGLFTYSLSTKRSSPDDGNDVSPYSLSPVSNKSQKLLRSPRKPTRKISKIPFKVLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 TPEKKGLFTYSLSTKRSSPDDGNDVSPYSLSPVSNKSQKLLRSPRKPTRKISKIPFKVLD
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD APELQDDFYLNLVDWSSLNVLSVGLGTCVYLWSACTSQVTRLCDLSVEGDSVTSVGWSER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 APELQDDFYLNLVDWSSLNVLSVGLGTCVYLWSACTSQVTRLCDLSVEGDSVTSVGWSER
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD GNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAEQLSSGSRDRMILQRDIRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 GNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAEQLSSGSRDRMILQRDIRT
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD PPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 PPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKA
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD IAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 IAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGY
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD SQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRSTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 SQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRSTK
              430       440       450       460       470       480

              490   
pF1KSD ESVSVLNLFTRIR
       :::::::::::::
NP_057 ESVSVLNLFTRIR
              490   

>>XP_005259630 (OMIM: 603619) PREDICTED: fizzy-related p  (496 aa)
 initn: 3286 init1: 3225 opt: 3284  Z-score: 2550.7  bits: 481.4 E(85289): 2.5e-135
Smith-Waterman score: 3284; 99.4% identity (99.4% similar) in 496 aa overlap (1-493:1-496)

               10        20        30        40        50        60
pF1KSD MDQDYERRLLRQIVIQNENTMPRVTEMRRTLTPASSPVSSPSKHGDRFIPSRAGANWSVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MDQDYERRLLRQIVIQNENTMPRVTEMRRTLTPASSPVSSPSKHGDRFIPSRAGANWSVN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD FHRINENEKSPSQNRKAKDATSDNGKDGLAYSALLKNELLGAGIEKVQDPQTEDRRLQPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FHRINENEKSPSQNRKAKDATSDNGKDGLAYSALLKNELLGAGIEKVQDPQTEDRRLQPS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD TPEKKGLFTYSLSTKRSSPDDGNDVSPYSLSPVSNKSQKLLRSPRKPTRKISKIPFKVLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TPEKKGLFTYSLSTKRSSPDDGNDVSPYSLSPVSNKSQKLLRSPRKPTRKISKIPFKVLD
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD APELQDDFYLNLVDWSSLNVLSVGLGTCVYLWSACTSQVTRLCDLSVEGDSVTSVGWSER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 APELQDDFYLNLVDWSSLNVLSVGLGTCVYLWSACTSQVTRLCDLSVEGDSVTSVGWSER
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD GNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAEQLSSGSRDRMILQRDIRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAEQLSSGSRDRMILQRDIRT
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD PPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKA
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD IAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGY
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD SQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRSTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRSTK
              430       440       450       460       470       480

                 490   
pF1KSD ---ESVSVLNLFTRIR
          :::::::::::::
XP_005 VKWESVSVLNLFTRIR
              490      

>>NP_001129670 (OMIM: 603619) fizzy-related protein homo  (496 aa)
 initn: 3286 init1: 3225 opt: 3284  Z-score: 2550.7  bits: 481.4 E(85289): 2.5e-135
Smith-Waterman score: 3284; 99.4% identity (99.4% similar) in 496 aa overlap (1-493:1-496)

               10        20        30        40        50        60
pF1KSD MDQDYERRLLRQIVIQNENTMPRVTEMRRTLTPASSPVSSPSKHGDRFIPSRAGANWSVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDQDYERRLLRQIVIQNENTMPRVTEMRRTLTPASSPVSSPSKHGDRFIPSRAGANWSVN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD FHRINENEKSPSQNRKAKDATSDNGKDGLAYSALLKNELLGAGIEKVQDPQTEDRRLQPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FHRINENEKSPSQNRKAKDATSDNGKDGLAYSALLKNELLGAGIEKVQDPQTEDRRLQPS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD TPEKKGLFTYSLSTKRSSPDDGNDVSPYSLSPVSNKSQKLLRSPRKPTRKISKIPFKVLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPEKKGLFTYSLSTKRSSPDDGNDVSPYSLSPVSNKSQKLLRSPRKPTRKISKIPFKVLD
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD APELQDDFYLNLVDWSSLNVLSVGLGTCVYLWSACTSQVTRLCDLSVEGDSVTSVGWSER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APELQDDFYLNLVDWSSLNVLSVGLGTCVYLWSACTSQVTRLCDLSVEGDSVTSVGWSER
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD GNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAEQLSSGSRDRMILQRDIRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAEQLSSGSRDRMILQRDIRT
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD PPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKA
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD IAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGY
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD SQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRSTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRSTK
              430       440       450       460       470       480

                 490   
pF1KSD ---ESVSVLNLFTRIR
          :::::::::::::
NP_001 VKWESVSVLNLFTRIR
              490      

>>XP_016882352 (OMIM: 603619) PREDICTED: fizzy-related p  (528 aa)
 initn: 3286 init1: 3225 opt: 3284  Z-score: 2550.3  bits: 481.5 E(85289): 2.6e-135
Smith-Waterman score: 3284; 99.4% identity (99.4% similar) in 496 aa overlap (1-493:33-528)

                                             10        20        30
pF1KSD                               MDQDYERRLLRQIVIQNENTMPRVTEMRRT
                                     ::::::::::::::::::::::::::::::
XP_016 GSCSGVWRAALVRPSPVDALTLPRAEPCLAMDQDYERRLLRQIVIQNENTMPRVTEMRRT
             10        20        30        40        50        60  

               40        50        60        70        80        90
pF1KSD LTPASSPVSSPSKHGDRFIPSRAGANWSVNFHRINENEKSPSQNRKAKDATSDNGKDGLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTPASSPVSSPSKHGDRFIPSRAGANWSVNFHRINENEKSPSQNRKAKDATSDNGKDGLA
             70        80        90       100       110       120  

              100       110       120       130       140       150
pF1KSD YSALLKNELLGAGIEKVQDPQTEDRRLQPSTPEKKGLFTYSLSTKRSSPDDGNDVSPYSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YSALLKNELLGAGIEKVQDPQTEDRRLQPSTPEKKGLFTYSLSTKRSSPDDGNDVSPYSL
            130       140       150       160       170       180  

              160       170       180       190       200       210
pF1KSD SPVSNKSQKLLRSPRKPTRKISKIPFKVLDAPELQDDFYLNLVDWSSLNVLSVGLGTCVY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPVSNKSQKLLRSPRKPTRKISKIPFKVLDAPELQDDFYLNLVDWSSLNVLSVGLGTCVY
            190       200       210       220       230       240  

              220       230       240       250       260       270
pF1KSD LWSACTSQVTRLCDLSVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LWSACTSQVTRLCDLSVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGH
            250       260       270       280       290       300  

              280       290       300       310       320       330
pF1KSD TARVGALAWNAEQLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TARVGALAWNAEQLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLAS
            310       320       330       340       350       360  

              340       350       360       370       380       390
pF1KSD GGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTG
            370       380       390       400       410       420  

              400       410       420       430       440       450
pF1KSD QPLQCIDTGSQVCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPLQCIDTGSQVCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLA
            430       440       450       460       470       480  

              460       470       480          490   
pF1KSD MSPDGEAIVTGAGDETLRFWNVFSKTRSTK---ESVSVLNLFTRIR
       ::::::::::::::::::::::::::::::   :::::::::::::
XP_016 MSPDGEAIVTGAGDETLRFWNVFSKTRSTKVKWESVSVLNLFTRIR
            490       500       510       520        

>>NP_001129669 (OMIM: 603619) fizzy-related protein homo  (404 aa)
 initn: 1856 init1: 1856 opt: 1856  Z-score: 1450.7  bits: 277.6 E(85289): 4.6e-74
Smith-Waterman score: 2518; 81.9% identity (81.9% similar) in 493 aa overlap (1-493:1-404)

               10        20        30        40        50        60
pF1KSD MDQDYERRLLRQIVIQNENTMPRVTEMRRTLTPASSPVSSPSKHGDRFIPSRAGANWSVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDQDYERRLLRQIVIQNENTMPRVTEMRRTLTPASSPVSSPSKHGDRFIPSRAGANWSVN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD FHRINENEKSPSQNRKAKDATSDNGKDGLAYSALLKNELLGAGIEKVQDPQTEDRRLQPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FHRINENEKSPSQNRKAKDATSDNGKDGLAYSALLKNELLGAGIEKVQDPQTEDRRLQPS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD TPEKKGLFTYSLSTKRSSPDDGNDVSPYSLSPVSNKSQKLLRSPRKPTRKISKIPFKVLD
       :::::::::                                                   
NP_001 TPEKKGLFT---------------------------------------------------
                                                                   

              190       200       210       220       230       240
pF1KSD APELQDDFYLNLVDWSSLNVLSVGLGTCVYLWSACTSQVTRLCDLSVEGDSVTSVGWSER
                                             ::::::::::::::::::::::
NP_001 --------------------------------------VTRLCDLSVEGDSVTSVGWSER
                                           130       140       150 

              250       260       270       280       290       300
pF1KSD GNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAEQLSSGSRDRMILQRDIRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAEQLSSGSRDRMILQRDIRT
             160       170       180       190       200       210 

              310       320       330       340       350       360
pF1KSD PPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKA
             220       230       240       250       260       270 

              370       380       390       400       410       420
pF1KSD IAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGY
             280       290       300       310       320       330 

              430       440       450       460       470       480
pF1KSD SQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRSTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRSTK
             340       350       360       370       380       390 

              490   
pF1KSD ESVSVLNLFTRIR
       :::::::::::::
NP_001 ESVSVLNLFTRIR
             400    

>>NP_001246 (OMIM: 603618) cell division cycle protein 2  (499 aa)
 initn: 1157 init1: 490 opt: 1094  Z-score: 862.0  bits: 169.0 E(85289): 2.8e-41
Smith-Waterman score: 1113; 41.3% identity (67.2% similar) in 458 aa overlap (29-473:58-473)

                 10        20        30         40         50      
pF1KSD   MDQDYERRLLRQIVIQNENTMPRVTEMRRTLTPASSPV-SSPSKHG-DRFIPSRAGAN
                                     ::   .:: : ..::: : ::.:: :..:.
NP_001 WQRKAKEAAGPAPSPMRAANRSHSAGRTPGRTPGKSSSKVQTTPSKPGGDRYIPHRSAAQ
        30        40        50        60        70        80       

         60             70         80        90       100          
pF1KSD WSVNFHRIN-----ENEKSPSQNRKAKD-ATSDNGKDGLAYSALLKNELLGAGIEKVQD-
         :    ..     :: ..:..... :  : . :: : .  . .:.  : :    : :. 
NP_001 MEVASFLLSKENQPENSQTPTKKEHQKAWALNLNGFD-VEEAKILR--LSG----KPQNA
        90       100       110       120        130             140

     110       120       130       140       150       160         
pF1KSD PQTEDRRLQPSTPEKKGLFTYSLSTKRSSPDDGNDVSPYSLSPVSNKSQKLLRSPRKPTR
       :.  . ::.             : .....:                       : ::  :
NP_001 PEGYQNRLK------------VLYSQKATPG----------------------SSRKTCR
                          150                             160      

     170       180       190       200       210       220         
pF1KSD KISKIPFKVLDAPELQDDFYLNLVDWSSLNVLSVGLGTCVYLWSACTSQVTRLCDLSVEG
        : ..: ..:::::...:.::::::::: :::.:.: . :::::: .... .: ..   :
NP_001 YIPSLPDRILDAPEIRNDYYLNLVDWSSGNVLAVALDNSVYLWSASSGDILQLLQMEQPG
        170       180       190       200       210       220      

     230       240       250       260       270       280         
pF1KSD DSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAEQLSSGSR
       . ..::.: ..:: .:::: .. ::.::.   :.:  . .:.::::.:.::.  ::::::
NP_001 EYISSVAWIKEGNYLAVGTSSAEVQLWDVQQQKRLRNMTSHSARVGSLSWNSYILSSGSR
        230       240       250       260       270       280      

     290       300       310       320       330       340         
pF1KSD DRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVW----NHSSL
       .  : ..:.:.   .    :.:: ::::::.:. : . :::::::: . ::    .... 
NP_001 SGHIHHHDVRVAE-HHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGW
        290        300       310       320       330       340     

         350       360       370       380       390       400     
pF1KSD SPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNL
        :.: .:.: .::::.:: : : ..::.::::.:: ::.::. .:  :. .:. ::::..
NP_001 VPLQTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQVCSI
         350       360       370       380       390       400     

         410       420       430       440       450       460     
pF1KSD AWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDE
        :: : .::.: ::..:::...::::....::.: ::. ::: :.::::: .....:.::
NP_001 LWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDGATVASAAADE
         410       420       430       440       450       460     

         470       480       490         
pF1KSD TLRFWNVFSKTRSTKESVSVLNLFTRIR      
       :::.:  :                          
NP_001 TLRLWRCFELDPARRREREKASAAKSSLIHQGIR
         470       480       490         

>>XP_016878353 (OMIM: 602703,616212) PREDICTED: katanin   (655 aa)
 initn: 283 init1: 137 opt: 320  Z-score: 263.7  bits: 58.7 E(85289): 6e-08
Smith-Waterman score: 320; 31.9% identity (60.9% similar) in 207 aa overlap (196-397:31-228)

         170       180       190       200        210       220    
pF1KSD KPTRKISKIPFKVLDAPELQDDFYLNLVDWSSLNVLSVGLGTC-VYLWSACTSQVTRLCD
                                     .:  .:..:   : : :::    .    : 
XP_016 MATPVVTKTAWKLQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPN----CI
               10        20        30        40        50          

          230         240       250       260       270       280  
pF1KSD LSVEGDS--VTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWN--
       .:. : .  : ::  .   .:...:...: ...::  :.: :  : :: : . .: ..  
XP_016 MSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPY
         60        70        80        90       100       110      

              290       300       310       320       330       340
pF1KSD AEQLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVW
       .: ..:::.:  :   :::        : .:: : :  :..: : . :::...:. . .:
XP_016 GEFVASGSQDTNIKLWDIRRKG--CVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLW
        120       130         140       150       160       170    

              350       360       370       380       390       400
pF1KSD NHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGS
       . .. . ....  : . :... . :... :::::  ..:: ::::.    : ..::.   
XP_016 DLTAGKMMSEFPGHTGPVNVVEFHPNEY-LLASG--SSDRTIRFWDLEKFQVVSCIEGEP
          180       190       200          210       220       230 

              410       420       430       440       450       460
pF1KSD QVCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVT
                                                                   
XP_016 GPVRSVLFNPDGCCLYSGCQDSLRVYGWEPERCFDVVLVNWGKVADLAICNDQLIGVAFS
             240       250       260       270       280       290 

>>XP_016878352 (OMIM: 602703,616212) PREDICTED: katanin   (655 aa)
 initn: 283 init1: 137 opt: 320  Z-score: 263.7  bits: 58.7 E(85289): 6e-08
Smith-Waterman score: 320; 31.9% identity (60.9% similar) in 207 aa overlap (196-397:31-228)

         170       180       190       200        210       220    
pF1KSD KPTRKISKIPFKVLDAPELQDDFYLNLVDWSSLNVLSVGLGTC-VYLWSACTSQVTRLCD
                                     .:  .:..:   : : :::    .    : 
XP_016 MATPVVTKTAWKLQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPN----CI
               10        20        30        40        50          

          230         240       250       260       270       280  
pF1KSD LSVEGDS--VTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWN--
       .:. : .  : ::  .   .:...:...: ...::  :.: :  : :: : . .: ..  
XP_016 MSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPY
         60        70        80        90       100       110      

              290       300       310       320       330       340
pF1KSD AEQLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVW
       .: ..:::.:  :   :::        : .:: : :  :..: : . :::...:. . .:
XP_016 GEFVASGSQDTNIKLWDIRRKG--CVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLW
        120       130         140       150       160       170    

              350       360       370       380       390       400
pF1KSD NHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGS
       . .. . ....  : . :... . :... :::::  ..:: ::::.    : ..::.   
XP_016 DLTAGKMMSEFPGHTGPVNVVEFHPNEY-LLASG--SSDRTIRFWDLEKFQVVSCIEGEP
          180       190       200          210       220       230 

              410       420       430       440       450       460
pF1KSD QVCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVT
                                                                   
XP_016 GPVRSVLFNPDGCCLYSGCQDSLRVYGWEPERCFDVVLVNWGKVADLAICNDQLIGVAFS
             240       250       260       270       280       290 

>>NP_005877 (OMIM: 602703,616212) katanin p80 WD40 repea  (655 aa)
 initn: 283 init1: 137 opt: 320  Z-score: 263.7  bits: 58.7 E(85289): 6e-08
Smith-Waterman score: 320; 31.9% identity (60.9% similar) in 207 aa overlap (196-397:31-228)

         170       180       190       200        210       220    
pF1KSD KPTRKISKIPFKVLDAPELQDDFYLNLVDWSSLNVLSVGLGTC-VYLWSACTSQVTRLCD
                                     .:  .:..:   : : :::    .    : 
NP_005 MATPVVTKTAWKLQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPN----CI
               10        20        30        40        50          

          230         240       250       260       270       280  
pF1KSD LSVEGDS--VTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWN--
       .:. : .  : ::  .   .:...:...: ...::  :.: :  : :: : . .: ..  
NP_005 MSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPY
         60        70        80        90       100       110      

              290       300       310       320       330       340
pF1KSD AEQLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVW
       .: ..:::.:  :   :::        : .:: : :  :..: : . :::...:. . .:
NP_005 GEFVASGSQDTNIKLWDIRRKG--CVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLW
        120       130         140       150       160       170    

              350       360       370       380       390       400
pF1KSD NHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGS
       . .. . ....  : . :... . :... :::::  ..:: ::::.    : ..::.   
NP_005 DLTAGKMMSEFPGHTGPVNVVEFHPNEY-LLASG--SSDRTIRFWDLEKFQVVSCIEGEP
          180       190       200          210       220       230 

              410       420       430       440       450       460
pF1KSD QVCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVT
                                                                   
NP_005 GPVRSVLFNPDGCCLYSGCQDSLRVYGWEPERCFDVVLVNWGKVADLAICNDQLIGVAFS
             240       250       260       270       280       290 

>>XP_006721186 (OMIM: 602703,616212) PREDICTED: katanin   (658 aa)
 initn: 283 init1: 137 opt: 320  Z-score: 263.7  bits: 58.7 E(85289): 6e-08
Smith-Waterman score: 320; 31.9% identity (60.9% similar) in 207 aa overlap (196-397:31-228)

         170       180       190       200        210       220    
pF1KSD KPTRKISKIPFKVLDAPELQDDFYLNLVDWSSLNVLSVGLGTC-VYLWSACTSQVTRLCD
                                     .:  .:..:   : : :::    .    : 
XP_006 MATPVVTKTAWKLQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPN----CI
               10        20        30        40        50          

          230         240       250       260       270       280  
pF1KSD LSVEGDS--VTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWN--
       .:. : .  : ::  .   .:...:...: ...::  :.: :  : :: : . .: ..  
XP_006 MSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPY
         60        70        80        90       100       110      

              290       300       310       320       330       340
pF1KSD AEQLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVW
       .: ..:::.:  :   :::        : .:: : :  :..: : . :::...:. . .:
XP_006 GEFVASGSQDTNIKLWDIRRKG--CVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLW
        120       130         140       150       160       170    

              350       360       370       380       390       400
pF1KSD NHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGS
       . .. . ....  : . :... . :... :::::  ..:: ::::.    : ..::.   
XP_006 DLTAGKMMSEFPGHTGPVNVVEFHPNEY-LLASG--SSDRTIRFWDLEKFQVVSCIEGEP
          180       190       200          210       220       230 

              410       420       430       440       450       460
pF1KSD QVCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVT
                                                                   
XP_006 GPVRSVLFNPDGCCLYSGCQDSLRVYGWEPERCFDVVLVNWGKVADLAICNDQLIGVAFS
             240       250       260       270       280       290 




493 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 05:30:38 2016 done: Thu Nov  3 05:30:40 2016
 Total Scan time: 10.290 Total Display time:  0.070

Function used was FASTA [36.3.4 Apr, 2011]
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