Result of FASTA (omim) for pF1KSDA1214
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KSDA1214, 396 aa
  1>>>pF1KSDA1214 396 - 396 aa - 396 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.7613+/-0.000367; mu= 15.7270+/- 0.023
 mean_var=110.2542+/-22.559, 0's: 0 Z-trim(115.6): 252  B-trim: 131 in 1/52
 Lambda= 0.122145
 statistics sampled from 25836 (26132) to 25836 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.675), E-opt: 0.2 (0.306), width:  16
 Scan time:  8.300

The best scores are:                                      opt bits E(85289)
NP_078815 (OMIM: 300439) E3 ubiquitin-protein liga ( 402)  451 90.4 8.1e-18
NP_919445 (OMIM: 300439) E3 ubiquitin-protein liga ( 428)  451 90.5 8.5e-18
NP_001307294 (OMIM: 610431) E3 ubiquitin-protein l ( 315)  283 60.7 5.6e-09
NP_001307292 (OMIM: 610431) E3 ubiquitin-protein l ( 315)  283 60.7 5.6e-09
NP_001307291 (OMIM: 610431) E3 ubiquitin-protein l ( 315)  283 60.7 5.6e-09
NP_001307293 (OMIM: 610431) E3 ubiquitin-protein l ( 315)  283 60.7 5.6e-09
XP_016879916 (OMIM: 610431) PREDICTED: E3 ubiquiti ( 350)  283 60.8   6e-09
NP_001307285 (OMIM: 610431) E3 ubiquitin-protein l ( 350)  283 60.8   6e-09
NP_001307290 (OMIM: 610431) E3 ubiquitin-protein l ( 350)  283 60.8   6e-09
NP_001307286 (OMIM: 610431) E3 ubiquitin-protein l ( 350)  283 60.8   6e-09
NP_056343 (OMIM: 610431) E3 ubiquitin-protein liga ( 350)  283 60.8   6e-09
NP_001307287 (OMIM: 610431) E3 ubiquitin-protein l ( 350)  283 60.8   6e-09
NP_001307289 (OMIM: 610431) E3 ubiquitin-protein l ( 350)  283 60.8   6e-09
NP_001307288 (OMIM: 610431) E3 ubiquitin-protein l ( 350)  283 60.8   6e-09
NP_115549 (OMIM: 612062) E3 ubiquitin-protein liga ( 836)  264 57.8 1.1e-07
XP_011528739 (OMIM: 612062) PREDICTED: E3 ubiquiti ( 841)  264 57.8 1.1e-07
XP_011528740 (OMIM: 612062) PREDICTED: E3 ubiquiti ( 841)  264 57.8 1.1e-07
XP_011528738 (OMIM: 612062) PREDICTED: E3 ubiquiti ( 841)  264 57.8 1.1e-07
XP_016884479 (OMIM: 612062) PREDICTED: E3 ubiquiti ( 841)  264 57.8 1.1e-07
XP_011528737 (OMIM: 612062) PREDICTED: E3 ubiquiti ( 841)  264 57.8 1.1e-07
XP_016861149 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 250)  257 56.0 1.1e-07
XP_016861147 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 262)  257 56.1 1.2e-07
XP_005247149 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 262)  257 56.1 1.2e-07
XP_011510678 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 262)  257 56.1 1.2e-07
XP_016861146 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 262)  257 56.1 1.2e-07
XP_016861145 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 262)  257 56.1 1.2e-07
XP_016861148 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 262)  257 56.1 1.2e-07
NP_001193927 (OMIM: 612062) E3 ubiquitin-protein l ( 936)  264 57.8 1.2e-07
XP_016861150 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 193)  254 55.4 1.4e-07
NP_009213 (OMIM: 609247) E3 ubiquitin-protein liga ( 381)  257 56.2 1.5e-07
XP_011510675 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 381)  257 56.2 1.5e-07
NP_899237 (OMIM: 609247) E3 ubiquitin-protein liga ( 381)  257 56.2 1.5e-07
XP_016861144 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 381)  257 56.2 1.5e-07
XP_011510676 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 381)  257 56.2 1.5e-07
XP_016861143 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 381)  257 56.2 1.5e-07
XP_016879917 (OMIM: 610431) PREDICTED: E3 ubiquiti ( 227)  242 53.4 6.6e-07
XP_016869786 (OMIM: 612488) PREDICTED: E3 ubiquiti ( 402)  214 48.7   3e-05
XP_016869785 (OMIM: 612488) PREDICTED: E3 ubiquiti ( 402)  214 48.7   3e-05
NP_919309 (OMIM: 612488) E3 ubiquitin-protein liga ( 432)  214 48.7 3.2e-05
XP_005251423 (OMIM: 612488) PREDICTED: E3 ubiquiti ( 432)  214 48.7 3.2e-05
XP_016869784 (OMIM: 612488) PREDICTED: E3 ubiquiti ( 432)  214 48.7 3.2e-05
XP_005251425 (OMIM: 612488) PREDICTED: E3 ubiquiti ( 432)  214 48.7 3.2e-05
XP_006716784 (OMIM: 612488) PREDICTED: E3 ubiquiti ( 432)  214 48.7 3.2e-05
XP_011516014 (OMIM: 612488) PREDICTED: E3 ubiquiti ( 432)  214 48.7 3.2e-05
XP_011516015 (OMIM: 612488) PREDICTED: E3 ubiquiti ( 432)  214 48.7 3.2e-05
NP_919313 (OMIM: 612488) E3 ubiquitin-protein liga ( 432)  214 48.7 3.2e-05
XP_005251424 (OMIM: 612488) PREDICTED: E3 ubiquiti ( 432)  214 48.7 3.2e-05
NP_919311 (OMIM: 612488) E3 ubiquitin-protein liga ( 432)  214 48.7 3.2e-05
XP_016869783 (OMIM: 612488) PREDICTED: E3 ubiquiti ( 444)  214 48.7 3.2e-05
NP_001292474 (OMIM: 612482,617108) E3 ubiquitin-pr ( 656)  216 49.2 3.3e-05


>>NP_078815 (OMIM: 300439) E3 ubiquitin-protein ligase R  (402 aa)
 initn: 750 init1: 429 opt: 451  Z-score: 440.9  bits: 90.4 E(85289): 8.1e-18
Smith-Waterman score: 715; 39.4% identity (58.5% similar) in 386 aa overlap (17-360:11-363)

               10        20         30        40        50         
pF1KSD MAMSLIQACCSLALSTWLLS-FCFVHLLCLDFTVAEKEEWYTAFVNITYAEPAPDPGAGA
                       :::  : :.  .  .:..       .:.:..:: . . .  :  
NP_078       MNQENRSSFFWLLVIFTFLLKITASFSM-------SAYVTVTYYNETSNYTA--
                     10        20               30        40       

      60        70        80        90       100       110         
pF1KSD AGGGGAELHTEKTECGRYGEHSPKQDARGEVVMASSAHDRLACDPNTKFAAPTRGKNWIA
                 :  ::: ::  ::  .: : ::   . ..  ::: ::.:.     : :::
NP_078 ---------IETCECGVYGLASPVANAMG-VVGIPKNNNYQACDHNTEFSNTK--KPWIA
                   50        60         70        80          90   

     120       130       140       150       160       170         
pF1KSD LIPKGNCTYRDKIRNAFLQNASAVVIFNVGSNTNETITMPHAGVEDIVAIMIPEPKGKEI
       :: .::::. .::..:  .::.::::.:.  . :.:: : . :. ::::::: . :: .:
NP_078 LIERGNCTFSEKIQTAGRRNADAVVIYNAPETGNQTIQMANFGAVDIVAIMIGNLKGTKI
           100       110       120       130       140       150   

     180       190          200                                    
pF1KSD VSLLERNITVTMYITIGTRN---LQKY-------------------------RRLGDA--
       .. ..:.: ::: : .: ..   ...:                         ::: .:  
NP_078 LQSIQRGIQVTMVIEVGKKHGPWVNHYSIFFVSVSFFIITAATVGYFIFYSARRLRNARA
           160       170       180       190       200       210   

                210       220       230       240       250        
pF1KSD -----------AKKAISKLQIRTIKKGDKETESDFDNCAVCIEGYKPNDVVRILPCRHLF
                  :::::..::.::.:.::::   : :.:::::: :::::.:::: : :.:
NP_078 QSRKQRQLKADAKKAIGRLQLRTLKQGDKEIGPDGDSCAVCIELYKPNDLVRILTCNHIF
           220       230       240       250       260       270   

      260       270       280       290       300       310        
pF1KSD HKSCVDPWLLDHRTCPMCKMNILKALGIPPNADCMDDLPTDFEGSLGGPPTNQITGASDT
       ::.:::::::.:::::::: .:::::::  ...       :   ::  : .:.:......
NP_078 HKTCVDPWLLEHRTCPMCKCDILKALGIEVDVE-------DGSVSLQVPVSNEISNSASS
           280       290       300              310       320      

      320       330       340       350       360       370        
pF1KSD TVNESSVTLDPAVRTVGALQVVQDTDPIPQEGDVIFTTNSEQEPAVSSDSDISLIMAMEV
         .: .   . :    ..   :: ::  : :  :  :..: :                  
NP_078 --HEEDNRSETASSGYAS---VQGTDEPPLEEHVQSTNESLQLVNHEANSVAVDVIPHVD
          330       340          350       360       370       380 

      380       390         
pF1KSD GLSDVELSTDQDCEEVKS   
                            
NP_078 NPTFEEDETPNQETAVREIKS
             390       400  

>>NP_919445 (OMIM: 300439) E3 ubiquitin-protein ligase R  (428 aa)
 initn: 744 init1: 429 opt: 451  Z-score: 440.5  bits: 90.5 E(85289): 8.5e-18
Smith-Waterman score: 695; 38.3% identity (59.4% similar) in 392 aa overlap (18-360:20-389)

                 10        20        30          40        50      
pF1KSD   MAMSLIQACCSLALSTWLLSFCFVHLLCLDFTVAEKEE--WYTAFVNITYAEPAPDPG
                          ::..::.  :  .   ..  :  : ::..:...  :     
NP_919 MGPPPGAGVSCRGGCGFSRLLAWCFLLALSPQAPGSRGAEAVW-TAYLNVSWRVPHT---
               10        20        30        40         50         

         60        70        80        90       100       110      
pF1KSD AGAAGGGGAELHTEKTECGRYGEHSPKQDARGEVVMASSAHDRLACDPNTKFAAPTR-GK
             :  .   : .: : ::. :: . . : .:  ..     ::.:.:.:..::  :.
NP_919 ------GVNRTVWELSEEGVYGQDSPLEPVAGVLVPPDGPGALNACNPHTNFTVPTVWGS
               60        70        80        90       100       110

             120        130       140       150       160       170
pF1KSD ----NWIALIPKGN-CTYRDKIRNAFLQNASAVVIFNVGSNTNETITMPHAGVEDIVAIM
           .:.::: .:. ::. :::. :. ..::..::::  .. ::.: : : :. ::::::
NP_919 TVQVSWLALIQRGGGCTFADKIHLAYERGASGAVIFNFPGTRNEVIPMSHPGAVDIVAIM
              120       130       140       150       160       170

              180       190          200                           
pF1KSD IPEPKGKEIVSLLERNITVTMYITIGTRN---LQKY------------------------
       : . :: .:.. ..:.: ::: : .: ..   ...:                        
NP_919 IGNLKGTKILQSIQRGIQVTMVIEVGKKHGPWVNHYSIFFVSVSFFIITAATVGYFIFYS
              180       190       200       210       220       230

                         210       220       230       240         
pF1KSD -RRLGDA-------------AKKAISKLQIRTIKKGDKETESDFDNCAVCIEGYKPNDVV
        ::: .:             :::::..::.::.:.::::   : :.:::::: :::::.:
NP_919 ARRLRNARAQSRKQRQLKADAKKAIGRLQLRTLKQGDKEIGPDGDSCAVCIELYKPNDLV
              240       250       260       270       280       290

     250       260       270       280       290       300         
pF1KSD RILPCRHLFHKSCVDPWLLDHRTCPMCKMNILKALGIPPNADCMDDLPTDFEGSLGGPPT
       ::: : :.:::.:::::::.:::::::: .:::::::  ...       :   ::  : .
NP_919 RILTCNHIFHKTCVDPWLLEHRTCPMCKCDILKALGIEVDVE-------DGSVSLQVPVS
              300       310       320       330              340   

     310       320       330       340       350       360         
pF1KSD NQITGASDTTVNESSVTLDPAVRTVGALQVVQDTDPIPQEGDVIFTTNSEQEPAVSSDSD
       :.:......  .: .   . :    ..   :: ::  : :  :  :..: :         
NP_919 NEISNSASS--HEEDNRSETASSGYAS---VQGTDEPPLEEHVQSTNESLQLVNHEANSV
           350         360          370       380       390        

     370       380       390         
pF1KSD ISLIMAMEVGLSDVELSTDQDCEEVKS   
                                     
NP_919 AVDVIPHVDNPTFEEDETPNQETAVREIKS
      400       410       420        

>>NP_001307294 (OMIM: 610431) E3 ubiquitin-protein ligas  (315 aa)
 initn: 312 init1: 168 opt: 283  Z-score: 282.2  bits: 60.7 E(85289): 5.6e-09
Smith-Waterman score: 331; 27.0% identity (54.6% similar) in 293 aa overlap (77-330:10-292)

         50        60        70        80        90       100      
pF1KSD TYAEPAPDPGAGAAGGGGAELHTEKTECGRYGEHSPKQDARGEVVMASSAHDRLACDP-N
                                     .:    ..  .: .:    ::   ::.:  
NP_001                      MDFADLPALFGATLSQEGLQGFLV---EAHPDNACSPIA
                                    10        20           30      

         110       120       130       140       150               
pF1KSD TKFAAPTRGKNWIALIPKGNCTYRDKIRNAFLQNASAVVIFNVGSNT-----------NE
           ::. :. .:::. . .:..  :. ::   . .:.:. ::.::            ..
NP_001 PPPPAPVNGSVFIALLRRFDCNFDLKVLNAQKAGYGAAVVHNVNSNELLNMVWNSEEIQQ
         40        50        60        70        80        90      

          160            170       180       190                   
pF1KSD TITMPHAGV-----EDIVAIMIPEPKGKEIVSLLERNITVTMYIT-----IG--------
        : .: . .     : . :... : :: ... . . .. . .:.      .:        
NP_001 QIWIPSVFIGERSSEYLRALFVYE-KGARVLLVPDNTFPLGYYLIPFTGIVGLLVLAMGA
        100       110       120        130       140       150     

           200       210       220       230       240       250   
pF1KSD ---TRNLQKYRRLGDAAKKAISKLQIRTIKKGDKETESDFDNCAVCIEGYKPNDVVRILP
          .: .:. .::    .. ..: :.. :   : .  ...: ::.:.. :. .: .:.::
NP_001 VMIARCIQHRKRL---QRNRLTKEQLKQIPTHDYQKGDQYDVCAICLDEYEDGDKLRVLP
         160          170       180       190       200       210  

           260       270        280       290       300            
pF1KSD CRHLFHKSCVDPWLLDHR-TCPMCKMNILKALGIPPNADCMDDLPTDFEGSLGGP---PT
       : : .:. :::::: . : :::.::. . ..   : . :  ..   . ::. : :   :.
NP_001 CAHAYHSRCVDPWLTQTRKTCPICKQPVHRG---PGDEDQEEETQGQEEGDEGEPRDHPA
            220       230       240          250       260         

     310         320       330       340       350       360       
pF1KSD NQITG--ASDTTVNESSVTLDPAVRTVGALQVVQDTDPIPQEGDVIFTTNSEQEPAVSSD
       .. :   .:. :.  :  .: ::                                     
NP_001 SERTPLLGSSPTLPTSFGSLAPAPLVFPGPSTDPPLSPPSSPVILV              
     270       280       290       300       310                   

>>NP_001307292 (OMIM: 610431) E3 ubiquitin-protein ligas  (315 aa)
 initn: 312 init1: 168 opt: 283  Z-score: 282.2  bits: 60.7 E(85289): 5.6e-09
Smith-Waterman score: 331; 27.0% identity (54.6% similar) in 293 aa overlap (77-330:10-292)

         50        60        70        80        90       100      
pF1KSD TYAEPAPDPGAGAAGGGGAELHTEKTECGRYGEHSPKQDARGEVVMASSAHDRLACDP-N
                                     .:    ..  .: .:    ::   ::.:  
NP_001                      MDFADLPALFGATLSQEGLQGFLV---EAHPDNACSPIA
                                    10        20           30      

         110       120       130       140       150               
pF1KSD TKFAAPTRGKNWIALIPKGNCTYRDKIRNAFLQNASAVVIFNVGSNT-----------NE
           ::. :. .:::. . .:..  :. ::   . .:.:. ::.::            ..
NP_001 PPPPAPVNGSVFIALLRRFDCNFDLKVLNAQKAGYGAAVVHNVNSNELLNMVWNSEEIQQ
         40        50        60        70        80        90      

          160            170       180       190                   
pF1KSD TITMPHAGV-----EDIVAIMIPEPKGKEIVSLLERNITVTMYIT-----IG--------
        : .: . .     : . :... : :: ... . . .. . .:.      .:        
NP_001 QIWIPSVFIGERSSEYLRALFVYE-KGARVLLVPDNTFPLGYYLIPFTGIVGLLVLAMGA
        100       110       120        130       140       150     

           200       210       220       230       240       250   
pF1KSD ---TRNLQKYRRLGDAAKKAISKLQIRTIKKGDKETESDFDNCAVCIEGYKPNDVVRILP
          .: .:. .::    .. ..: :.. :   : .  ...: ::.:.. :. .: .:.::
NP_001 VMIARCIQHRKRL---QRNRLTKEQLKQIPTHDYQKGDQYDVCAICLDEYEDGDKLRVLP
         160          170       180       190       200       210  

           260       270        280       290       300            
pF1KSD CRHLFHKSCVDPWLLDHR-TCPMCKMNILKALGIPPNADCMDDLPTDFEGSLGGP---PT
       : : .:. :::::: . : :::.::. . ..   : . :  ..   . ::. : :   :.
NP_001 CAHAYHSRCVDPWLTQTRKTCPICKQPVHRG---PGDEDQEEETQGQEEGDEGEPRDHPA
            220       230       240          250       260         

     310         320       330       340       350       360       
pF1KSD NQITG--ASDTTVNESSVTLDPAVRTVGALQVVQDTDPIPQEGDVIFTTNSEQEPAVSSD
       .. :   .:. :.  :  .: ::                                     
NP_001 SERTPLLGSSPTLPTSFGSLAPAPLVFPGPSTDPPLSPPSSPVILV              
     270       280       290       300       310                   

>>NP_001307291 (OMIM: 610431) E3 ubiquitin-protein ligas  (315 aa)
 initn: 312 init1: 168 opt: 283  Z-score: 282.2  bits: 60.7 E(85289): 5.6e-09
Smith-Waterman score: 331; 27.0% identity (54.6% similar) in 293 aa overlap (77-330:10-292)

         50        60        70        80        90       100      
pF1KSD TYAEPAPDPGAGAAGGGGAELHTEKTECGRYGEHSPKQDARGEVVMASSAHDRLACDP-N
                                     .:    ..  .: .:    ::   ::.:  
NP_001                      MDFADLPALFGATLSQEGLQGFLV---EAHPDNACSPIA
                                    10        20           30      

         110       120       130       140       150               
pF1KSD TKFAAPTRGKNWIALIPKGNCTYRDKIRNAFLQNASAVVIFNVGSNT-----------NE
           ::. :. .:::. . .:..  :. ::   . .:.:. ::.::            ..
NP_001 PPPPAPVNGSVFIALLRRFDCNFDLKVLNAQKAGYGAAVVHNVNSNELLNMVWNSEEIQQ
         40        50        60        70        80        90      

          160            170       180       190                   
pF1KSD TITMPHAGV-----EDIVAIMIPEPKGKEIVSLLERNITVTMYIT-----IG--------
        : .: . .     : . :... : :: ... . . .. . .:.      .:        
NP_001 QIWIPSVFIGERSSEYLRALFVYE-KGARVLLVPDNTFPLGYYLIPFTGIVGLLVLAMGA
        100       110       120        130       140       150     

           200       210       220       230       240       250   
pF1KSD ---TRNLQKYRRLGDAAKKAISKLQIRTIKKGDKETESDFDNCAVCIEGYKPNDVVRILP
          .: .:. .::    .. ..: :.. :   : .  ...: ::.:.. :. .: .:.::
NP_001 VMIARCIQHRKRL---QRNRLTKEQLKQIPTHDYQKGDQYDVCAICLDEYEDGDKLRVLP
         160          170       180       190       200       210  

           260       270        280       290       300            
pF1KSD CRHLFHKSCVDPWLLDHR-TCPMCKMNILKALGIPPNADCMDDLPTDFEGSLGGP---PT
       : : .:. :::::: . : :::.::. . ..   : . :  ..   . ::. : :   :.
NP_001 CAHAYHSRCVDPWLTQTRKTCPICKQPVHRG---PGDEDQEEETQGQEEGDEGEPRDHPA
            220       230       240          250       260         

     310         320       330       340       350       360       
pF1KSD NQITG--ASDTTVNESSVTLDPAVRTVGALQVVQDTDPIPQEGDVIFTTNSEQEPAVSSD
       .. :   .:. :.  :  .: ::                                     
NP_001 SERTPLLGSSPTLPTSFGSLAPAPLVFPGPSTDPPLSPPSSPVILV              
     270       280       290       300       310                   

>>NP_001307293 (OMIM: 610431) E3 ubiquitin-protein ligas  (315 aa)
 initn: 312 init1: 168 opt: 283  Z-score: 282.2  bits: 60.7 E(85289): 5.6e-09
Smith-Waterman score: 331; 27.0% identity (54.6% similar) in 293 aa overlap (77-330:10-292)

         50        60        70        80        90       100      
pF1KSD TYAEPAPDPGAGAAGGGGAELHTEKTECGRYGEHSPKQDARGEVVMASSAHDRLACDP-N
                                     .:    ..  .: .:    ::   ::.:  
NP_001                      MDFADLPALFGATLSQEGLQGFLV---EAHPDNACSPIA
                                    10        20           30      

         110       120       130       140       150               
pF1KSD TKFAAPTRGKNWIALIPKGNCTYRDKIRNAFLQNASAVVIFNVGSNT-----------NE
           ::. :. .:::. . .:..  :. ::   . .:.:. ::.::            ..
NP_001 PPPPAPVNGSVFIALLRRFDCNFDLKVLNAQKAGYGAAVVHNVNSNELLNMVWNSEEIQQ
         40        50        60        70        80        90      

          160            170       180       190                   
pF1KSD TITMPHAGV-----EDIVAIMIPEPKGKEIVSLLERNITVTMYIT-----IG--------
        : .: . .     : . :... : :: ... . . .. . .:.      .:        
NP_001 QIWIPSVFIGERSSEYLRALFVYE-KGARVLLVPDNTFPLGYYLIPFTGIVGLLVLAMGA
        100       110       120        130       140       150     

           200       210       220       230       240       250   
pF1KSD ---TRNLQKYRRLGDAAKKAISKLQIRTIKKGDKETESDFDNCAVCIEGYKPNDVVRILP
          .: .:. .::    .. ..: :.. :   : .  ...: ::.:.. :. .: .:.::
NP_001 VMIARCIQHRKRL---QRNRLTKEQLKQIPTHDYQKGDQYDVCAICLDEYEDGDKLRVLP
         160          170       180       190       200       210  

           260       270        280       290       300            
pF1KSD CRHLFHKSCVDPWLLDHR-TCPMCKMNILKALGIPPNADCMDDLPTDFEGSLGGP---PT
       : : .:. :::::: . : :::.::. . ..   : . :  ..   . ::. : :   :.
NP_001 CAHAYHSRCVDPWLTQTRKTCPICKQPVHRG---PGDEDQEEETQGQEEGDEGEPRDHPA
            220       230       240          250       260         

     310         320       330       340       350       360       
pF1KSD NQITG--ASDTTVNESSVTLDPAVRTVGALQVVQDTDPIPQEGDVIFTTNSEQEPAVSSD
       .. :   .:. :.  :  .: ::                                     
NP_001 SERTPLLGSSPTLPTSFGSLAPAPLVFPGPSTDPPLSPPSSPVILV              
     270       280       290       300       310                   

>>XP_016879916 (OMIM: 610431) PREDICTED: E3 ubiquitin-pr  (350 aa)
 initn: 290 init1: 168 opt: 283  Z-score: 281.6  bits: 60.8 E(85289): 6e-09
Smith-Waterman score: 331; 27.0% identity (54.6% similar) in 293 aa overlap (77-330:45-327)

         50        60        70        80        90       100      
pF1KSD TYAEPAPDPGAGAAGGGGAELHTEKTECGRYGEHSPKQDARGEVVMASSAHDRLACDP-N
                                     .:    ..  .: .:    ::   ::.:  
XP_016 VLWGAAPTRGLIRATSDHNASMDFADLPALFGATLSQEGLQGFLV---EAHPDNACSPIA
           20        30        40        50           60        70 

         110       120       130       140       150               
pF1KSD TKFAAPTRGKNWIALIPKGNCTYRDKIRNAFLQNASAVVIFNVGSNT-----------NE
           ::. :. .:::. . .:..  :. ::   . .:.:. ::.::            ..
XP_016 PPPPAPVNGSVFIALLRRFDCNFDLKVLNAQKAGYGAAVVHNVNSNELLNMVWNSEEIQQ
              80        90       100       110       120       130 

          160            170       180       190                   
pF1KSD TITMPHAGV-----EDIVAIMIPEPKGKEIVSLLERNITVTMYIT-----IG--------
        : .: . .     : . :... : :: ... . . .. . .:.      .:        
XP_016 QIWIPSVFIGERSSEYLRALFVYE-KGARVLLVPDNTFPLGYYLIPFTGIVGLLVLAMGA
             140       150        160       170       180       190

           200       210       220       230       240       250   
pF1KSD ---TRNLQKYRRLGDAAKKAISKLQIRTIKKGDKETESDFDNCAVCIEGYKPNDVVRILP
          .: .:. .::    .. ..: :.. :   : .  ...: ::.:.. :. .: .:.::
XP_016 VMIARCIQHRKRL---QRNRLTKEQLKQIPTHDYQKGDQYDVCAICLDEYEDGDKLRVLP
              200          210       220       230       240       

           260       270        280       290       300            
pF1KSD CRHLFHKSCVDPWLLDHR-TCPMCKMNILKALGIPPNADCMDDLPTDFEGSLGGP---PT
       : : .:. :::::: . : :::.::. . ..   : . :  ..   . ::. : :   :.
XP_016 CAHAYHSRCVDPWLTQTRKTCPICKQPVHRG---PGDEDQEEETQGQEEGDEGEPRDHPA
       250       260       270          280       290       300    

     310         320       330       340       350       360       
pF1KSD NQITG--ASDTTVNESSVTLDPAVRTVGALQVVQDTDPIPQEGDVIFTTNSEQEPAVSSD
       .. :   .:. :.  :  .: ::                                     
XP_016 SERTPLLGSSPTLPTSFGSLAPAPLVFPGPSTDPPLSPPSSPVILV              
          310       320       330       340       350              

>>NP_001307285 (OMIM: 610431) E3 ubiquitin-protein ligas  (350 aa)
 initn: 290 init1: 168 opt: 283  Z-score: 281.6  bits: 60.8 E(85289): 6e-09
Smith-Waterman score: 331; 27.0% identity (54.6% similar) in 293 aa overlap (77-330:45-327)

         50        60        70        80        90       100      
pF1KSD TYAEPAPDPGAGAAGGGGAELHTEKTECGRYGEHSPKQDARGEVVMASSAHDRLACDP-N
                                     .:    ..  .: .:    ::   ::.:  
NP_001 VLWGAAPTRGLIRATSDHNASMDFADLPALFGATLSQEGLQGFLV---EAHPDNACSPIA
           20        30        40        50           60        70 

         110       120       130       140       150               
pF1KSD TKFAAPTRGKNWIALIPKGNCTYRDKIRNAFLQNASAVVIFNVGSNT-----------NE
           ::. :. .:::. . .:..  :. ::   . .:.:. ::.::            ..
NP_001 PPPPAPVNGSVFIALLRRFDCNFDLKVLNAQKAGYGAAVVHNVNSNELLNMVWNSEEIQQ
              80        90       100       110       120       130 

          160            170       180       190                   
pF1KSD TITMPHAGV-----EDIVAIMIPEPKGKEIVSLLERNITVTMYIT-----IG--------
        : .: . .     : . :... : :: ... . . .. . .:.      .:        
NP_001 QIWIPSVFIGERSSEYLRALFVYE-KGARVLLVPDNTFPLGYYLIPFTGIVGLLVLAMGA
             140       150        160       170       180       190

           200       210       220       230       240       250   
pF1KSD ---TRNLQKYRRLGDAAKKAISKLQIRTIKKGDKETESDFDNCAVCIEGYKPNDVVRILP
          .: .:. .::    .. ..: :.. :   : .  ...: ::.:.. :. .: .:.::
NP_001 VMIARCIQHRKRL---QRNRLTKEQLKQIPTHDYQKGDQYDVCAICLDEYEDGDKLRVLP
              200          210       220       230       240       

           260       270        280       290       300            
pF1KSD CRHLFHKSCVDPWLLDHR-TCPMCKMNILKALGIPPNADCMDDLPTDFEGSLGGP---PT
       : : .:. :::::: . : :::.::. . ..   : . :  ..   . ::. : :   :.
NP_001 CAHAYHSRCVDPWLTQTRKTCPICKQPVHRG---PGDEDQEEETQGQEEGDEGEPRDHPA
       250       260       270          280       290       300    

     310         320       330       340       350       360       
pF1KSD NQITG--ASDTTVNESSVTLDPAVRTVGALQVVQDTDPIPQEGDVIFTTNSEQEPAVSSD
       .. :   .:. :.  :  .: ::                                     
NP_001 SERTPLLGSSPTLPTSFGSLAPAPLVFPGPSTDPPLSPPSSPVILV              
          310       320       330       340       350              

>>NP_001307290 (OMIM: 610431) E3 ubiquitin-protein ligas  (350 aa)
 initn: 290 init1: 168 opt: 283  Z-score: 281.6  bits: 60.8 E(85289): 6e-09
Smith-Waterman score: 331; 27.0% identity (54.6% similar) in 293 aa overlap (77-330:45-327)

         50        60        70        80        90       100      
pF1KSD TYAEPAPDPGAGAAGGGGAELHTEKTECGRYGEHSPKQDARGEVVMASSAHDRLACDP-N
                                     .:    ..  .: .:    ::   ::.:  
NP_001 VLWGAAPTRGLIRATSDHNASMDFADLPALFGATLSQEGLQGFLV---EAHPDNACSPIA
           20        30        40        50           60        70 

         110       120       130       140       150               
pF1KSD TKFAAPTRGKNWIALIPKGNCTYRDKIRNAFLQNASAVVIFNVGSNT-----------NE
           ::. :. .:::. . .:..  :. ::   . .:.:. ::.::            ..
NP_001 PPPPAPVNGSVFIALLRRFDCNFDLKVLNAQKAGYGAAVVHNVNSNELLNMVWNSEEIQQ
              80        90       100       110       120       130 

          160            170       180       190                   
pF1KSD TITMPHAGV-----EDIVAIMIPEPKGKEIVSLLERNITVTMYIT-----IG--------
        : .: . .     : . :... : :: ... . . .. . .:.      .:        
NP_001 QIWIPSVFIGERSSEYLRALFVYE-KGARVLLVPDNTFPLGYYLIPFTGIVGLLVLAMGA
             140       150        160       170       180       190

           200       210       220       230       240       250   
pF1KSD ---TRNLQKYRRLGDAAKKAISKLQIRTIKKGDKETESDFDNCAVCIEGYKPNDVVRILP
          .: .:. .::    .. ..: :.. :   : .  ...: ::.:.. :. .: .:.::
NP_001 VMIARCIQHRKRL---QRNRLTKEQLKQIPTHDYQKGDQYDVCAICLDEYEDGDKLRVLP
              200          210       220       230       240       

           260       270        280       290       300            
pF1KSD CRHLFHKSCVDPWLLDHR-TCPMCKMNILKALGIPPNADCMDDLPTDFEGSLGGP---PT
       : : .:. :::::: . : :::.::. . ..   : . :  ..   . ::. : :   :.
NP_001 CAHAYHSRCVDPWLTQTRKTCPICKQPVHRG---PGDEDQEEETQGQEEGDEGEPRDHPA
       250       260       270          280       290       300    

     310         320       330       340       350       360       
pF1KSD NQITG--ASDTTVNESSVTLDPAVRTVGALQVVQDTDPIPQEGDVIFTTNSEQEPAVSSD
       .. :   .:. :.  :  .: ::                                     
NP_001 SERTPLLGSSPTLPTSFGSLAPAPLVFPGPSTDPPLSPPSSPVILV              
          310       320       330       340       350              

>>NP_001307286 (OMIM: 610431) E3 ubiquitin-protein ligas  (350 aa)
 initn: 290 init1: 168 opt: 283  Z-score: 281.6  bits: 60.8 E(85289): 6e-09
Smith-Waterman score: 331; 27.0% identity (54.6% similar) in 293 aa overlap (77-330:45-327)

         50        60        70        80        90       100      
pF1KSD TYAEPAPDPGAGAAGGGGAELHTEKTECGRYGEHSPKQDARGEVVMASSAHDRLACDP-N
                                     .:    ..  .: .:    ::   ::.:  
NP_001 VLWGAAPTRGLIRATSDHNASMDFADLPALFGATLSQEGLQGFLV---EAHPDNACSPIA
           20        30        40        50           60        70 

         110       120       130       140       150               
pF1KSD TKFAAPTRGKNWIALIPKGNCTYRDKIRNAFLQNASAVVIFNVGSNT-----------NE
           ::. :. .:::. . .:..  :. ::   . .:.:. ::.::            ..
NP_001 PPPPAPVNGSVFIALLRRFDCNFDLKVLNAQKAGYGAAVVHNVNSNELLNMVWNSEEIQQ
              80        90       100       110       120       130 

          160            170       180       190                   
pF1KSD TITMPHAGV-----EDIVAIMIPEPKGKEIVSLLERNITVTMYIT-----IG--------
        : .: . .     : . :... : :: ... . . .. . .:.      .:        
NP_001 QIWIPSVFIGERSSEYLRALFVYE-KGARVLLVPDNTFPLGYYLIPFTGIVGLLVLAMGA
             140       150        160       170       180       190

           200       210       220       230       240       250   
pF1KSD ---TRNLQKYRRLGDAAKKAISKLQIRTIKKGDKETESDFDNCAVCIEGYKPNDVVRILP
          .: .:. .::    .. ..: :.. :   : .  ...: ::.:.. :. .: .:.::
NP_001 VMIARCIQHRKRL---QRNRLTKEQLKQIPTHDYQKGDQYDVCAICLDEYEDGDKLRVLP
              200          210       220       230       240       

           260       270        280       290       300            
pF1KSD CRHLFHKSCVDPWLLDHR-TCPMCKMNILKALGIPPNADCMDDLPTDFEGSLGGP---PT
       : : .:. :::::: . : :::.::. . ..   : . :  ..   . ::. : :   :.
NP_001 CAHAYHSRCVDPWLTQTRKTCPICKQPVHRG---PGDEDQEEETQGQEEGDEGEPRDHPA
       250       260       270          280       290       300    

     310         320       330       340       350       360       
pF1KSD NQITG--ASDTTVNESSVTLDPAVRTVGALQVVQDTDPIPQEGDVIFTTNSEQEPAVSSD
       .. :   .:. :.  :  .: ::                                     
NP_001 SERTPLLGSSPTLPTSFGSLAPAPLVFPGPSTDPPLSPPSSPVILV              
          310       320       330       340       350              




396 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 05:24:13 2016 done: Thu Nov  3 05:24:15 2016
 Total Scan time:  8.300 Total Display time:  0.040

Function used was FASTA [36.3.4 Apr, 2011]
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