Result of FASTA (omim) for pF1KSDA1034
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KSDA1034, 733 aa
  1>>>pF1KSDA1034 733 - 733 aa - 733 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 8.7418+/-0.00033; mu= 6.1652+/- 0.021
 mean_var=181.7820+/-36.462, 0's: 0 Z-trim(121.5): 29  B-trim: 0 in 0/57
 Lambda= 0.095126
 statistics sampled from 38262 (38292) to 38262 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.753), E-opt: 0.2 (0.449), width:  16
 Scan time: 12.020

The best scores are:                                      opt bits E(85289)
XP_011509142 (OMIM: 608148,612313) PREDICTED: DNA- ( 733) 4855 678.6 2.5e-194
NP_001165988 (OMIM: 608148,612313) DNA-binding pro ( 733) 4855 678.6 2.5e-194
XP_006712435 (OMIM: 608148,612313) PREDICTED: DNA- ( 733) 4855 678.6 2.5e-194
NP_056080 (OMIM: 608148,612313) DNA-binding protei ( 733) 4855 678.6 2.5e-194
NP_001165980 (OMIM: 608148,612313) DNA-binding pro ( 733) 4855 678.6 2.5e-194
XP_005246453 (OMIM: 608148,612313) PREDICTED: DNA- ( 675) 4452 623.2  1e-177
XP_016859145 (OMIM: 608148,612313) PREDICTED: DNA- ( 675) 4452 623.2  1e-177
NP_001124482 (OMIM: 602075) DNA-binding protein SA ( 763) 2371 337.7 1.1e-91
NP_002962 (OMIM: 602075) DNA-binding protein SATB1 ( 763) 2371 337.7 1.1e-91
NP_001309803 (OMIM: 602075) DNA-binding protein SA ( 763) 2371 337.7 1.1e-91
NP_001309804 (OMIM: 602075) DNA-binding protein SA ( 763) 2371 337.7 1.1e-91
NP_001309801 (OMIM: 602075) DNA-binding protein SA ( 763) 2371 337.7 1.1e-91
NP_001309802 (OMIM: 602075) DNA-binding protein SA ( 763) 2371 337.7 1.1e-91
NP_001309805 (OMIM: 602075) DNA-binding protein SA ( 691) 2350 334.8 7.3e-91
NP_001182399 (OMIM: 602075) DNA-binding protein SA ( 795) 2312 329.6   3e-89
XP_011532291 (OMIM: 602075) PREDICTED: DNA-binding ( 795) 2312 329.6   3e-89
NP_001309800 (OMIM: 602075) DNA-binding protein SA ( 795) 2312 329.6   3e-89
XP_011532290 (OMIM: 602075) PREDICTED: DNA-binding ( 795) 2312 329.6   3e-89
XP_011532292 (OMIM: 602075) PREDICTED: DNA-binding ( 534) 1962 281.4 6.3e-75


>>XP_011509142 (OMIM: 608148,612313) PREDICTED: DNA-bind  (733 aa)
 initn: 4855 init1: 4855 opt: 4855  Z-score: 3609.8  bits: 678.6 E(85289): 2.5e-194
Smith-Waterman score: 4855; 100.0% identity (100.0% similar) in 733 aa overlap (1-733:1-733)

               10        20        30        40        50        60
pF1KSD MERRSESPCLRDSPDRRSGSPDVKGPPPVKVARLEQNGSPMGARGRPNGAVAKAVGGLMI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MERRSESPCLRDSPDRRSGSPDVKGPPPVKVARLEQNGSPMGARGRPNGAVAKAVGGLMI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD PVFCVVEQLDGSLEYDNREEHAEFVLVRKDVLFSQLVETALLALGYSHSSAAQAQGIIKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVFCVVEQLDGSLEYDNREEHAEFVLVRKDVLFSQLVETALLALGYSHSSAAQAQGIIKL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD GRWNPLPLSYVTDAPDATVADMLQDVYHVVTLKIQLQSCSKLEDLPAEQWNHATVRNALK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GRWNPLPLSYVTDAPDATVADMLQDVYHVVTLKIQLQSCSKLEDLPAEQWNHATVRNALK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD ELLKEMNQSTLAKECPLSQSMISSIVNSTYYANVSATKCQEFGRWYKKYKKIKVERVERE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELLKEMNQSTLAKECPLSQSMISSIVNSTYYANVSATKCQEFGRWYKKYKKIKVERVERE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD NLSDYCVLGQRPMHLPNMNQLASLGKTNEQSPHSQIHHSTPIRNQVPALQPIMSPGLLSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLSDYCVLGQRPMHLPNMNQLASLGKTNEQSPHSQIHHSTPIRNQVPALQPIMSPGLLSP
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD QLSPQLVRQQIAMAHLINQQIAVSRLLAHQHPQAINQQFLNHPPIPRAVKPEPTNSSVEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLSPQLVRQQIAMAHLINQQIAVSRLLAHQHPQAINQQFLNHPPIPRAVKPEPTNSSVEV
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD SPDIYQQVRDELKRASVSQAVFARVAFNRTQGLLSEILRKEEDPRTASQSLLVNLRAMQN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPDIYQQVRDELKRASVSQAVFARVAFNRTQGLLSEILRKEEDPRTASQSLLVNLRAMQN
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD FLNLPEVERDRIYQDERERSMNPNVSMVSSASSSPSSSRTPQAKTSTPTTDLPIKVDGAN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLNLPEVERDRIYQDERERSMNPNVSMVSSASSSPSSSRTPQAKTSTPTTDLPIKVDGAN
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD INITAAIYDEIQQEMKRAKVSQALFAKVAANKSQGWLCELLRWKENPSPENRTLWENLCT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 INITAAIYDEIQQEMKRAKVSQALFAKVAANKSQGWLCELLRWKENPSPENRTLWENLCT
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD IRRFLNLPQHERDVIYEEESRHHHSERMQHVVQLPPEPVQVLHRQQSQPAKESSPPREEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IRRFLNLPQHERDVIYEEESRHHHSERMQHVVQLPPEPVQVLHRQQSQPAKESSPPREEA
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD PPPPPPTEDSCAKKPRSRTKISLEALGILQSFIHDVGLYPDQEAIHTLSAQLDLPKHTII
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPPPPPTEDSCAKKPRSRTKISLEALGILQSFIHDVGLYPDQEAIHTLSAQLDLPKHTII
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD KFFQNQRYHVKHHGKLKEHLGSAVDVAEYKDEELLTESEENDSEEGSEEMYKVEAEEENA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KFFQNQRYHVKHHGKLKEHLGSAVDVAEYKDEELLTESEENDSEEGSEEMYKVEAEEENA
              670       680       690       700       710       720

              730   
pF1KSD DKSKAAPAEIDQR
       :::::::::::::
XP_011 DKSKAAPAEIDQR
              730   

>>NP_001165988 (OMIM: 608148,612313) DNA-binding protein  (733 aa)
 initn: 4855 init1: 4855 opt: 4855  Z-score: 3609.8  bits: 678.6 E(85289): 2.5e-194
Smith-Waterman score: 4855; 100.0% identity (100.0% similar) in 733 aa overlap (1-733:1-733)

               10        20        30        40        50        60
pF1KSD MERRSESPCLRDSPDRRSGSPDVKGPPPVKVARLEQNGSPMGARGRPNGAVAKAVGGLMI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MERRSESPCLRDSPDRRSGSPDVKGPPPVKVARLEQNGSPMGARGRPNGAVAKAVGGLMI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD PVFCVVEQLDGSLEYDNREEHAEFVLVRKDVLFSQLVETALLALGYSHSSAAQAQGIIKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVFCVVEQLDGSLEYDNREEHAEFVLVRKDVLFSQLVETALLALGYSHSSAAQAQGIIKL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD GRWNPLPLSYVTDAPDATVADMLQDVYHVVTLKIQLQSCSKLEDLPAEQWNHATVRNALK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GRWNPLPLSYVTDAPDATVADMLQDVYHVVTLKIQLQSCSKLEDLPAEQWNHATVRNALK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD ELLKEMNQSTLAKECPLSQSMISSIVNSTYYANVSATKCQEFGRWYKKYKKIKVERVERE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELLKEMNQSTLAKECPLSQSMISSIVNSTYYANVSATKCQEFGRWYKKYKKIKVERVERE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD NLSDYCVLGQRPMHLPNMNQLASLGKTNEQSPHSQIHHSTPIRNQVPALQPIMSPGLLSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLSDYCVLGQRPMHLPNMNQLASLGKTNEQSPHSQIHHSTPIRNQVPALQPIMSPGLLSP
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD QLSPQLVRQQIAMAHLINQQIAVSRLLAHQHPQAINQQFLNHPPIPRAVKPEPTNSSVEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLSPQLVRQQIAMAHLINQQIAVSRLLAHQHPQAINQQFLNHPPIPRAVKPEPTNSSVEV
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD SPDIYQQVRDELKRASVSQAVFARVAFNRTQGLLSEILRKEEDPRTASQSLLVNLRAMQN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPDIYQQVRDELKRASVSQAVFARVAFNRTQGLLSEILRKEEDPRTASQSLLVNLRAMQN
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD FLNLPEVERDRIYQDERERSMNPNVSMVSSASSSPSSSRTPQAKTSTPTTDLPIKVDGAN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLNLPEVERDRIYQDERERSMNPNVSMVSSASSSPSSSRTPQAKTSTPTTDLPIKVDGAN
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD INITAAIYDEIQQEMKRAKVSQALFAKVAANKSQGWLCELLRWKENPSPENRTLWENLCT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 INITAAIYDEIQQEMKRAKVSQALFAKVAANKSQGWLCELLRWKENPSPENRTLWENLCT
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD IRRFLNLPQHERDVIYEEESRHHHSERMQHVVQLPPEPVQVLHRQQSQPAKESSPPREEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IRRFLNLPQHERDVIYEEESRHHHSERMQHVVQLPPEPVQVLHRQQSQPAKESSPPREEA
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD PPPPPPTEDSCAKKPRSRTKISLEALGILQSFIHDVGLYPDQEAIHTLSAQLDLPKHTII
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPPPPPTEDSCAKKPRSRTKISLEALGILQSFIHDVGLYPDQEAIHTLSAQLDLPKHTII
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD KFFQNQRYHVKHHGKLKEHLGSAVDVAEYKDEELLTESEENDSEEGSEEMYKVEAEEENA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KFFQNQRYHVKHHGKLKEHLGSAVDVAEYKDEELLTESEENDSEEGSEEMYKVEAEEENA
              670       680       690       700       710       720

              730   
pF1KSD DKSKAAPAEIDQR
       :::::::::::::
NP_001 DKSKAAPAEIDQR
              730   

>>XP_006712435 (OMIM: 608148,612313) PREDICTED: DNA-bind  (733 aa)
 initn: 4855 init1: 4855 opt: 4855  Z-score: 3609.8  bits: 678.6 E(85289): 2.5e-194
Smith-Waterman score: 4855; 100.0% identity (100.0% similar) in 733 aa overlap (1-733:1-733)

               10        20        30        40        50        60
pF1KSD MERRSESPCLRDSPDRRSGSPDVKGPPPVKVARLEQNGSPMGARGRPNGAVAKAVGGLMI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MERRSESPCLRDSPDRRSGSPDVKGPPPVKVARLEQNGSPMGARGRPNGAVAKAVGGLMI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD PVFCVVEQLDGSLEYDNREEHAEFVLVRKDVLFSQLVETALLALGYSHSSAAQAQGIIKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PVFCVVEQLDGSLEYDNREEHAEFVLVRKDVLFSQLVETALLALGYSHSSAAQAQGIIKL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD GRWNPLPLSYVTDAPDATVADMLQDVYHVVTLKIQLQSCSKLEDLPAEQWNHATVRNALK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GRWNPLPLSYVTDAPDATVADMLQDVYHVVTLKIQLQSCSKLEDLPAEQWNHATVRNALK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD ELLKEMNQSTLAKECPLSQSMISSIVNSTYYANVSATKCQEFGRWYKKYKKIKVERVERE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ELLKEMNQSTLAKECPLSQSMISSIVNSTYYANVSATKCQEFGRWYKKYKKIKVERVERE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD NLSDYCVLGQRPMHLPNMNQLASLGKTNEQSPHSQIHHSTPIRNQVPALQPIMSPGLLSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NLSDYCVLGQRPMHLPNMNQLASLGKTNEQSPHSQIHHSTPIRNQVPALQPIMSPGLLSP
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD QLSPQLVRQQIAMAHLINQQIAVSRLLAHQHPQAINQQFLNHPPIPRAVKPEPTNSSVEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QLSPQLVRQQIAMAHLINQQIAVSRLLAHQHPQAINQQFLNHPPIPRAVKPEPTNSSVEV
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD SPDIYQQVRDELKRASVSQAVFARVAFNRTQGLLSEILRKEEDPRTASQSLLVNLRAMQN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SPDIYQQVRDELKRASVSQAVFARVAFNRTQGLLSEILRKEEDPRTASQSLLVNLRAMQN
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD FLNLPEVERDRIYQDERERSMNPNVSMVSSASSSPSSSRTPQAKTSTPTTDLPIKVDGAN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FLNLPEVERDRIYQDERERSMNPNVSMVSSASSSPSSSRTPQAKTSTPTTDLPIKVDGAN
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD INITAAIYDEIQQEMKRAKVSQALFAKVAANKSQGWLCELLRWKENPSPENRTLWENLCT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 INITAAIYDEIQQEMKRAKVSQALFAKVAANKSQGWLCELLRWKENPSPENRTLWENLCT
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD IRRFLNLPQHERDVIYEEESRHHHSERMQHVVQLPPEPVQVLHRQQSQPAKESSPPREEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IRRFLNLPQHERDVIYEEESRHHHSERMQHVVQLPPEPVQVLHRQQSQPAKESSPPREEA
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD PPPPPPTEDSCAKKPRSRTKISLEALGILQSFIHDVGLYPDQEAIHTLSAQLDLPKHTII
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PPPPPPTEDSCAKKPRSRTKISLEALGILQSFIHDVGLYPDQEAIHTLSAQLDLPKHTII
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD KFFQNQRYHVKHHGKLKEHLGSAVDVAEYKDEELLTESEENDSEEGSEEMYKVEAEEENA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KFFQNQRYHVKHHGKLKEHLGSAVDVAEYKDEELLTESEENDSEEGSEEMYKVEAEEENA
              670       680       690       700       710       720

              730   
pF1KSD DKSKAAPAEIDQR
       :::::::::::::
XP_006 DKSKAAPAEIDQR
              730   

>>NP_056080 (OMIM: 608148,612313) DNA-binding protein SA  (733 aa)
 initn: 4855 init1: 4855 opt: 4855  Z-score: 3609.8  bits: 678.6 E(85289): 2.5e-194
Smith-Waterman score: 4855; 100.0% identity (100.0% similar) in 733 aa overlap (1-733:1-733)

               10        20        30        40        50        60
pF1KSD MERRSESPCLRDSPDRRSGSPDVKGPPPVKVARLEQNGSPMGARGRPNGAVAKAVGGLMI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MERRSESPCLRDSPDRRSGSPDVKGPPPVKVARLEQNGSPMGARGRPNGAVAKAVGGLMI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD PVFCVVEQLDGSLEYDNREEHAEFVLVRKDVLFSQLVETALLALGYSHSSAAQAQGIIKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 PVFCVVEQLDGSLEYDNREEHAEFVLVRKDVLFSQLVETALLALGYSHSSAAQAQGIIKL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD GRWNPLPLSYVTDAPDATVADMLQDVYHVVTLKIQLQSCSKLEDLPAEQWNHATVRNALK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 GRWNPLPLSYVTDAPDATVADMLQDVYHVVTLKIQLQSCSKLEDLPAEQWNHATVRNALK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD ELLKEMNQSTLAKECPLSQSMISSIVNSTYYANVSATKCQEFGRWYKKYKKIKVERVERE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 ELLKEMNQSTLAKECPLSQSMISSIVNSTYYANVSATKCQEFGRWYKKYKKIKVERVERE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD NLSDYCVLGQRPMHLPNMNQLASLGKTNEQSPHSQIHHSTPIRNQVPALQPIMSPGLLSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 NLSDYCVLGQRPMHLPNMNQLASLGKTNEQSPHSQIHHSTPIRNQVPALQPIMSPGLLSP
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD QLSPQLVRQQIAMAHLINQQIAVSRLLAHQHPQAINQQFLNHPPIPRAVKPEPTNSSVEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 QLSPQLVRQQIAMAHLINQQIAVSRLLAHQHPQAINQQFLNHPPIPRAVKPEPTNSSVEV
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD SPDIYQQVRDELKRASVSQAVFARVAFNRTQGLLSEILRKEEDPRTASQSLLVNLRAMQN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 SPDIYQQVRDELKRASVSQAVFARVAFNRTQGLLSEILRKEEDPRTASQSLLVNLRAMQN
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD FLNLPEVERDRIYQDERERSMNPNVSMVSSASSSPSSSRTPQAKTSTPTTDLPIKVDGAN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 FLNLPEVERDRIYQDERERSMNPNVSMVSSASSSPSSSRTPQAKTSTPTTDLPIKVDGAN
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD INITAAIYDEIQQEMKRAKVSQALFAKVAANKSQGWLCELLRWKENPSPENRTLWENLCT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 INITAAIYDEIQQEMKRAKVSQALFAKVAANKSQGWLCELLRWKENPSPENRTLWENLCT
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD IRRFLNLPQHERDVIYEEESRHHHSERMQHVVQLPPEPVQVLHRQQSQPAKESSPPREEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 IRRFLNLPQHERDVIYEEESRHHHSERMQHVVQLPPEPVQVLHRQQSQPAKESSPPREEA
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD PPPPPPTEDSCAKKPRSRTKISLEALGILQSFIHDVGLYPDQEAIHTLSAQLDLPKHTII
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 PPPPPPTEDSCAKKPRSRTKISLEALGILQSFIHDVGLYPDQEAIHTLSAQLDLPKHTII
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD KFFQNQRYHVKHHGKLKEHLGSAVDVAEYKDEELLTESEENDSEEGSEEMYKVEAEEENA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 KFFQNQRYHVKHHGKLKEHLGSAVDVAEYKDEELLTESEENDSEEGSEEMYKVEAEEENA
              670       680       690       700       710       720

              730   
pF1KSD DKSKAAPAEIDQR
       :::::::::::::
NP_056 DKSKAAPAEIDQR
              730   

>>NP_001165980 (OMIM: 608148,612313) DNA-binding protein  (733 aa)
 initn: 4855 init1: 4855 opt: 4855  Z-score: 3609.8  bits: 678.6 E(85289): 2.5e-194
Smith-Waterman score: 4855; 100.0% identity (100.0% similar) in 733 aa overlap (1-733:1-733)

               10        20        30        40        50        60
pF1KSD MERRSESPCLRDSPDRRSGSPDVKGPPPVKVARLEQNGSPMGARGRPNGAVAKAVGGLMI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MERRSESPCLRDSPDRRSGSPDVKGPPPVKVARLEQNGSPMGARGRPNGAVAKAVGGLMI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD PVFCVVEQLDGSLEYDNREEHAEFVLVRKDVLFSQLVETALLALGYSHSSAAQAQGIIKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVFCVVEQLDGSLEYDNREEHAEFVLVRKDVLFSQLVETALLALGYSHSSAAQAQGIIKL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD GRWNPLPLSYVTDAPDATVADMLQDVYHVVTLKIQLQSCSKLEDLPAEQWNHATVRNALK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GRWNPLPLSYVTDAPDATVADMLQDVYHVVTLKIQLQSCSKLEDLPAEQWNHATVRNALK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD ELLKEMNQSTLAKECPLSQSMISSIVNSTYYANVSATKCQEFGRWYKKYKKIKVERVERE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELLKEMNQSTLAKECPLSQSMISSIVNSTYYANVSATKCQEFGRWYKKYKKIKVERVERE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD NLSDYCVLGQRPMHLPNMNQLASLGKTNEQSPHSQIHHSTPIRNQVPALQPIMSPGLLSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLSDYCVLGQRPMHLPNMNQLASLGKTNEQSPHSQIHHSTPIRNQVPALQPIMSPGLLSP
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD QLSPQLVRQQIAMAHLINQQIAVSRLLAHQHPQAINQQFLNHPPIPRAVKPEPTNSSVEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLSPQLVRQQIAMAHLINQQIAVSRLLAHQHPQAINQQFLNHPPIPRAVKPEPTNSSVEV
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD SPDIYQQVRDELKRASVSQAVFARVAFNRTQGLLSEILRKEEDPRTASQSLLVNLRAMQN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPDIYQQVRDELKRASVSQAVFARVAFNRTQGLLSEILRKEEDPRTASQSLLVNLRAMQN
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD FLNLPEVERDRIYQDERERSMNPNVSMVSSASSSPSSSRTPQAKTSTPTTDLPIKVDGAN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLNLPEVERDRIYQDERERSMNPNVSMVSSASSSPSSSRTPQAKTSTPTTDLPIKVDGAN
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD INITAAIYDEIQQEMKRAKVSQALFAKVAANKSQGWLCELLRWKENPSPENRTLWENLCT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 INITAAIYDEIQQEMKRAKVSQALFAKVAANKSQGWLCELLRWKENPSPENRTLWENLCT
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD IRRFLNLPQHERDVIYEEESRHHHSERMQHVVQLPPEPVQVLHRQQSQPAKESSPPREEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IRRFLNLPQHERDVIYEEESRHHHSERMQHVVQLPPEPVQVLHRQQSQPAKESSPPREEA
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD PPPPPPTEDSCAKKPRSRTKISLEALGILQSFIHDVGLYPDQEAIHTLSAQLDLPKHTII
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPPPPPTEDSCAKKPRSRTKISLEALGILQSFIHDVGLYPDQEAIHTLSAQLDLPKHTII
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD KFFQNQRYHVKHHGKLKEHLGSAVDVAEYKDEELLTESEENDSEEGSEEMYKVEAEEENA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KFFQNQRYHVKHHGKLKEHLGSAVDVAEYKDEELLTESEENDSEEGSEEMYKVEAEEENA
              670       680       690       700       710       720

              730   
pF1KSD DKSKAAPAEIDQR
       :::::::::::::
NP_001 DKSKAAPAEIDQR
              730   

>>XP_005246453 (OMIM: 608148,612313) PREDICTED: DNA-bind  (675 aa)
 initn: 4452 init1: 4452 opt: 4452  Z-score: 3311.5  bits: 623.2 E(85289): 1e-177
Smith-Waterman score: 4452; 100.0% identity (100.0% similar) in 675 aa overlap (59-733:1-675)

       30        40        50        60        70        80        
pF1KSD VKVARLEQNGSPMGARGRPNGAVAKAVGGLMIPVFCVVEQLDGSLEYDNREEHAEFVLVR
                                     ::::::::::::::::::::::::::::::
XP_005                               MIPVFCVVEQLDGSLEYDNREEHAEFVLVR
                                             10        20        30

       90       100       110       120       130       140        
pF1KSD KDVLFSQLVETALLALGYSHSSAAQAQGIIKLGRWNPLPLSYVTDAPDATVADMLQDVYH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KDVLFSQLVETALLALGYSHSSAAQAQGIIKLGRWNPLPLSYVTDAPDATVADMLQDVYH
               40        50        60        70        80        90

      150       160       170       180       190       200        
pF1KSD VVTLKIQLQSCSKLEDLPAEQWNHATVRNALKELLKEMNQSTLAKECPLSQSMISSIVNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VVTLKIQLQSCSKLEDLPAEQWNHATVRNALKELLKEMNQSTLAKECPLSQSMISSIVNS
              100       110       120       130       140       150

      210       220       230       240       250       260        
pF1KSD TYYANVSATKCQEFGRWYKKYKKIKVERVERENLSDYCVLGQRPMHLPNMNQLASLGKTN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TYYANVSATKCQEFGRWYKKYKKIKVERVERENLSDYCVLGQRPMHLPNMNQLASLGKTN
              160       170       180       190       200       210

      270       280       290       300       310       320        
pF1KSD EQSPHSQIHHSTPIRNQVPALQPIMSPGLLSPQLSPQLVRQQIAMAHLINQQIAVSRLLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EQSPHSQIHHSTPIRNQVPALQPIMSPGLLSPQLSPQLVRQQIAMAHLINQQIAVSRLLA
              220       230       240       250       260       270

      330       340       350       360       370       380        
pF1KSD HQHPQAINQQFLNHPPIPRAVKPEPTNSSVEVSPDIYQQVRDELKRASVSQAVFARVAFN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HQHPQAINQQFLNHPPIPRAVKPEPTNSSVEVSPDIYQQVRDELKRASVSQAVFARVAFN
              280       290       300       310       320       330

      390       400       410       420       430       440        
pF1KSD RTQGLLSEILRKEEDPRTASQSLLVNLRAMQNFLNLPEVERDRIYQDERERSMNPNVSMV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RTQGLLSEILRKEEDPRTASQSLLVNLRAMQNFLNLPEVERDRIYQDERERSMNPNVSMV
              340       350       360       370       380       390

      450       460       470       480       490       500        
pF1KSD SSASSSPSSSRTPQAKTSTPTTDLPIKVDGANINITAAIYDEIQQEMKRAKVSQALFAKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSASSSPSSSRTPQAKTSTPTTDLPIKVDGANINITAAIYDEIQQEMKRAKVSQALFAKV
              400       410       420       430       440       450

      510       520       530       540       550       560        
pF1KSD AANKSQGWLCELLRWKENPSPENRTLWENLCTIRRFLNLPQHERDVIYEEESRHHHSERM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AANKSQGWLCELLRWKENPSPENRTLWENLCTIRRFLNLPQHERDVIYEEESRHHHSERM
              460       470       480       490       500       510

      570       580       590       600       610       620        
pF1KSD QHVVQLPPEPVQVLHRQQSQPAKESSPPREEAPPPPPPTEDSCAKKPRSRTKISLEALGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QHVVQLPPEPVQVLHRQQSQPAKESSPPREEAPPPPPPTEDSCAKKPRSRTKISLEALGI
              520       530       540       550       560       570

      630       640       650       660       670       680        
pF1KSD LQSFIHDVGLYPDQEAIHTLSAQLDLPKHTIIKFFQNQRYHVKHHGKLKEHLGSAVDVAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LQSFIHDVGLYPDQEAIHTLSAQLDLPKHTIIKFFQNQRYHVKHHGKLKEHLGSAVDVAE
              580       590       600       610       620       630

      690       700       710       720       730   
pF1KSD YKDEELLTESEENDSEEGSEEMYKVEAEEENADKSKAAPAEIDQR
       :::::::::::::::::::::::::::::::::::::::::::::
XP_005 YKDEELLTESEENDSEEGSEEMYKVEAEEENADKSKAAPAEIDQR
              640       650       660       670     

>>XP_016859145 (OMIM: 608148,612313) PREDICTED: DNA-bind  (675 aa)
 initn: 4452 init1: 4452 opt: 4452  Z-score: 3311.5  bits: 623.2 E(85289): 1e-177
Smith-Waterman score: 4452; 100.0% identity (100.0% similar) in 675 aa overlap (59-733:1-675)

       30        40        50        60        70        80        
pF1KSD VKVARLEQNGSPMGARGRPNGAVAKAVGGLMIPVFCVVEQLDGSLEYDNREEHAEFVLVR
                                     ::::::::::::::::::::::::::::::
XP_016                               MIPVFCVVEQLDGSLEYDNREEHAEFVLVR
                                             10        20        30

       90       100       110       120       130       140        
pF1KSD KDVLFSQLVETALLALGYSHSSAAQAQGIIKLGRWNPLPLSYVTDAPDATVADMLQDVYH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDVLFSQLVETALLALGYSHSSAAQAQGIIKLGRWNPLPLSYVTDAPDATVADMLQDVYH
               40        50        60        70        80        90

      150       160       170       180       190       200        
pF1KSD VVTLKIQLQSCSKLEDLPAEQWNHATVRNALKELLKEMNQSTLAKECPLSQSMISSIVNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVTLKIQLQSCSKLEDLPAEQWNHATVRNALKELLKEMNQSTLAKECPLSQSMISSIVNS
              100       110       120       130       140       150

      210       220       230       240       250       260        
pF1KSD TYYANVSATKCQEFGRWYKKYKKIKVERVERENLSDYCVLGQRPMHLPNMNQLASLGKTN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TYYANVSATKCQEFGRWYKKYKKIKVERVERENLSDYCVLGQRPMHLPNMNQLASLGKTN
              160       170       180       190       200       210

      270       280       290       300       310       320        
pF1KSD EQSPHSQIHHSTPIRNQVPALQPIMSPGLLSPQLSPQLVRQQIAMAHLINQQIAVSRLLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQSPHSQIHHSTPIRNQVPALQPIMSPGLLSPQLSPQLVRQQIAMAHLINQQIAVSRLLA
              220       230       240       250       260       270

      330       340       350       360       370       380        
pF1KSD HQHPQAINQQFLNHPPIPRAVKPEPTNSSVEVSPDIYQQVRDELKRASVSQAVFARVAFN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HQHPQAINQQFLNHPPIPRAVKPEPTNSSVEVSPDIYQQVRDELKRASVSQAVFARVAFN
              280       290       300       310       320       330

      390       400       410       420       430       440        
pF1KSD RTQGLLSEILRKEEDPRTASQSLLVNLRAMQNFLNLPEVERDRIYQDERERSMNPNVSMV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTQGLLSEILRKEEDPRTASQSLLVNLRAMQNFLNLPEVERDRIYQDERERSMNPNVSMV
              340       350       360       370       380       390

      450       460       470       480       490       500        
pF1KSD SSASSSPSSSRTPQAKTSTPTTDLPIKVDGANINITAAIYDEIQQEMKRAKVSQALFAKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSASSSPSSSRTPQAKTSTPTTDLPIKVDGANINITAAIYDEIQQEMKRAKVSQALFAKV
              400       410       420       430       440       450

      510       520       530       540       550       560        
pF1KSD AANKSQGWLCELLRWKENPSPENRTLWENLCTIRRFLNLPQHERDVIYEEESRHHHSERM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AANKSQGWLCELLRWKENPSPENRTLWENLCTIRRFLNLPQHERDVIYEEESRHHHSERM
              460       470       480       490       500       510

      570       580       590       600       610       620        
pF1KSD QHVVQLPPEPVQVLHRQQSQPAKESSPPREEAPPPPPPTEDSCAKKPRSRTKISLEALGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QHVVQLPPEPVQVLHRQQSQPAKESSPPREEAPPPPPPTEDSCAKKPRSRTKISLEALGI
              520       530       540       550       560       570

      630       640       650       660       670       680        
pF1KSD LQSFIHDVGLYPDQEAIHTLSAQLDLPKHTIIKFFQNQRYHVKHHGKLKEHLGSAVDVAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQSFIHDVGLYPDQEAIHTLSAQLDLPKHTIIKFFQNQRYHVKHHGKLKEHLGSAVDVAE
              580       590       600       610       620       630

      690       700       710       720       730   
pF1KSD YKDEELLTESEENDSEEGSEEMYKVEAEEENADKSKAAPAEIDQR
       :::::::::::::::::::::::::::::::::::::::::::::
XP_016 YKDEELLTESEENDSEEGSEEMYKVEAEEENADKSKAAPAEIDQR
              640       650       660       670     

>>NP_001124482 (OMIM: 602075) DNA-binding protein SATB1   (763 aa)
 initn: 2339 init1: 1042 opt: 2371  Z-score: 1767.2  bits: 337.7 E(85289): 1.1e-91
Smith-Waterman score: 2873; 62.1% identity (80.4% similar) in 760 aa overlap (1-718:1-748)

               10        20        30        40        50          
pF1KSD MERRSESPCLRDSPDRRSGSPDVKGPPPVKVARLEQNGSPMGARGRPNGAVAKAVG----
       :.. .:.   ..  .  ..  : :::: .:.:::::::::.: ::: ... ::  :    
NP_001 MDHLNEATQGKEHSEMSNNVSDPKGPP-AKIARLEQNGSPLG-RGRLGSTGAKMQGVPLK
               10        20         30        40         50        

                     60        70        80        90       100    
pF1KSD ------------GLMIPVFCVVEQLDGSLEYDNREEHAEFVLVRKDVLFSQLVETALLAL
                   : :.:::::::. ....::: .::::::::::::.::.::.: :::.:
NP_001 HSGHLMKTNLRKGTMLPVFCVVEHYENAIEYDCKEEHAEFVLVRKDMLFNQLIEMALLSL
       60        70        80        90       100       110        

          110       120       130       140       150       160    
pF1KSD GYSHSSAAQAQGIIKLGRWNPLPLSYVTDAPDATVADMLQDVYHVVTLKIQLQSCSKLED
       ::::::::::.:.:..:.:::.::::::::::::::::::::::::::::::.:: ::::
NP_001 GYSHSSAAQAKGLIQVGKWNPVPLSYVTDAPDATVADMLQDVYHVVTLKIQLHSCPKLED
      120       130       140       150       160       170        

          170       180       190       200       210       220    
pF1KSD LPAEQWNHATVRNALKELLKEMNQSTLAKECPLSQSMISSIVNSTYYANVSATKCQEFGR
       :: :::.:.:::::::.:::.::::.::::::::::::::::::::::::::.:::::::
NP_001 LPPEQWSHTTVRNALKDLLKDMNQSSLAKECPLSQSMISSIVNSTYYANVSAAKCQEFGR
      180       190       200       210       220       230        

          230       240       250       260       270         280  
pF1KSD WYKKYKKIKVERVERENLSDYCVLGQRPMHLPNMNQLASLGKTNEQSPH-SQIHH-STP-
       :::..:: :   :: ..::.   :.:.  .  :..:    :.: :: :  .:. : : : 
NP_001 WYKHFKKTKDMMVEMDSLSE---LSQQGANHVNFGQQPVPGNTAEQPPSPAQLSHGSQPS
      240       250          260       270       280       290     

             290       300       310       320       330       340 
pF1KSD IRNQVPALQPIMSPGLLSPQLSPQLVRQQIAMAHLINQQIAVSRLLAHQHPQAINQQFLN
       .:. .: :.:    ::.:  .::::: ::..::.:.::: ::.::::.:   ..:::.::
NP_001 VRTPLPNLHP----GLVSTPISPQLVNQQLVMAQLLNQQYAVNRLLAQQ---SLNQQYLN
         300           310       320       330       340           

               350         360       370       380       390       
pF1KSD HPP-IPRAV-KP--EPTNSSVEVSPDIYQQVRDELKRASVSQAVFARVAFNRTQGLLSEI
       ::: . :.. ::  . .....::: .::: ::::::::..::::::::::::::::::::
NP_001 HPPPVSRSMNKPLEQQVSTNTEVSSEIYQWVRDELKRAGISQAVFARVAFNRTQGLLSEI
      350       360       370       380       390       400        

       400       410       420       430       440       450       
pF1KSD LRKEEDPRTASQSLLVNLRAMQNFLNLPEVERDRIYQDERERSMNPNVSMVSSASSSPSS
       :::::::.:::::::::::::::::.:::.:::::::::::::.:   .:  .   :   
NP_001 LRKEEDPKTASQSLLVNLRAMQNFLQLPEAERDRIYQDERERSLNAASAMGPAPLISTPP
      410       420       430       440       450       460        

       460       470       480       490       500       510       
pF1KSD SRTPQAKTSTPTTDLPIKVDGANINITAAIYDEIQQEMKRAKVSQALFAKVAANKSQGWL
       :: ::.::.: .:.   : .. ..::.:.::::::::::::::::::::::::.::::::
NP_001 SRPPQVKTATIATERNGKPENNTMNINASIYDEIQQEMKRAKVSQALFAKVAATKSQGWL
      470       480       490       500       510       520        

       520       530       540       550       560         570     
pF1KSD CELLRWKENPSPENRTLWENLCTIRRFLNLPQHERDVIYEEESR--HHHSERMQHVVQLP
       ::::::::.::::::::::::  :::::.::: :::.:::.::   :::..:  :....:
NP_001 CELLRWKEDPSPENRTLWENLSMIRRFLSLPQPERDAIYEQESNAVHHHGDRPPHIIHVP
      530       540       550       560       570       580        

         580       590          600              610               
pF1KSD PEPVQVLHRQQSQPAKESS---PPREEAPP---P--PP--PTEDSCA-------KKPRSR
        : .:  ..::.:  ....   ::. .  :   :  ::  ::  : :       .: : :
NP_001 AEQIQQQQQQQQQQQQQQQAPPPPQPQQQPQTGPRLPPRQPTVASPAESDEENRQKTRPR
      590       600       610       620       630       640        

      620       630       640       650       660       670        
pF1KSD TKISLEALGILQSFIHDVGLYPDQEAIHTLSAQLDLPKHTIIKFFQNQRYHVKHHGKLKE
       ::::.::::::::::.:::::::.:::.::::::::::.:::::::::::..:::::::.
NP_001 TKISVEALGILQSFIQDVGLYPDEEAIQTLSAQLDLPKYTIIKFFQNQRYYLKHHGKLKD
      650       660       670       680       690       700        

      680       690       700       710       720       730   
pF1KSD HLGSAVDVAEYKDEELLTESEENDSEEGSEEMYKVEAEEENADKSKAAPAEIDQR
       . :  :::::::.:::: . ::. ...... ...:. :::               
NP_001 NSGLEVDVAEYKEEELLKDLEESVQDKNTNTLFSVKLEEELSVEGNTDINTDLKD
      710       720       730       740       750       760   

>>NP_002962 (OMIM: 602075) DNA-binding protein SATB1 iso  (763 aa)
 initn: 2339 init1: 1042 opt: 2371  Z-score: 1767.2  bits: 337.7 E(85289): 1.1e-91
Smith-Waterman score: 2873; 62.1% identity (80.4% similar) in 760 aa overlap (1-718:1-748)

               10        20        30        40        50          
pF1KSD MERRSESPCLRDSPDRRSGSPDVKGPPPVKVARLEQNGSPMGARGRPNGAVAKAVG----
       :.. .:.   ..  .  ..  : :::: .:.:::::::::.: ::: ... ::  :    
NP_002 MDHLNEATQGKEHSEMSNNVSDPKGPP-AKIARLEQNGSPLG-RGRLGSTGAKMQGVPLK
               10        20         30        40         50        

                     60        70        80        90       100    
pF1KSD ------------GLMIPVFCVVEQLDGSLEYDNREEHAEFVLVRKDVLFSQLVETALLAL
                   : :.:::::::. ....::: .::::::::::::.::.::.: :::.:
NP_002 HSGHLMKTNLRKGTMLPVFCVVEHYENAIEYDCKEEHAEFVLVRKDMLFNQLIEMALLSL
       60        70        80        90       100       110        

          110       120       130       140       150       160    
pF1KSD GYSHSSAAQAQGIIKLGRWNPLPLSYVTDAPDATVADMLQDVYHVVTLKIQLQSCSKLED
       ::::::::::.:.:..:.:::.::::::::::::::::::::::::::::::.:: ::::
NP_002 GYSHSSAAQAKGLIQVGKWNPVPLSYVTDAPDATVADMLQDVYHVVTLKIQLHSCPKLED
      120       130       140       150       160       170        

          170       180       190       200       210       220    
pF1KSD LPAEQWNHATVRNALKELLKEMNQSTLAKECPLSQSMISSIVNSTYYANVSATKCQEFGR
       :: :::.:.:::::::.:::.::::.::::::::::::::::::::::::::.:::::::
NP_002 LPPEQWSHTTVRNALKDLLKDMNQSSLAKECPLSQSMISSIVNSTYYANVSAAKCQEFGR
      180       190       200       210       220       230        

          230       240       250       260       270         280  
pF1KSD WYKKYKKIKVERVERENLSDYCVLGQRPMHLPNMNQLASLGKTNEQSPH-SQIHH-STP-
       :::..:: :   :: ..::.   :.:.  .  :..:    :.: :: :  .:. : : : 
NP_002 WYKHFKKTKDMMVEMDSLSE---LSQQGANHVNFGQQPVPGNTAEQPPSPAQLSHGSQPS
      240       250          260       270       280       290     

             290       300       310       320       330       340 
pF1KSD IRNQVPALQPIMSPGLLSPQLSPQLVRQQIAMAHLINQQIAVSRLLAHQHPQAINQQFLN
       .:. .: :.:    ::.:  .::::: ::..::.:.::: ::.::::.:   ..:::.::
NP_002 VRTPLPNLHP----GLVSTPISPQLVNQQLVMAQLLNQQYAVNRLLAQQ---SLNQQYLN
         300           310       320       330       340           

               350         360       370       380       390       
pF1KSD HPP-IPRAV-KP--EPTNSSVEVSPDIYQQVRDELKRASVSQAVFARVAFNRTQGLLSEI
       ::: . :.. ::  . .....::: .::: ::::::::..::::::::::::::::::::
NP_002 HPPPVSRSMNKPLEQQVSTNTEVSSEIYQWVRDELKRAGISQAVFARVAFNRTQGLLSEI
      350       360       370       380       390       400        

       400       410       420       430       440       450       
pF1KSD LRKEEDPRTASQSLLVNLRAMQNFLNLPEVERDRIYQDERERSMNPNVSMVSSASSSPSS
       :::::::.:::::::::::::::::.:::.:::::::::::::.:   .:  .   :   
NP_002 LRKEEDPKTASQSLLVNLRAMQNFLQLPEAERDRIYQDERERSLNAASAMGPAPLISTPP
      410       420       430       440       450       460        

       460       470       480       490       500       510       
pF1KSD SRTPQAKTSTPTTDLPIKVDGANINITAAIYDEIQQEMKRAKVSQALFAKVAANKSQGWL
       :: ::.::.: .:.   : .. ..::.:.::::::::::::::::::::::::.::::::
NP_002 SRPPQVKTATIATERNGKPENNTMNINASIYDEIQQEMKRAKVSQALFAKVAATKSQGWL
      470       480       490       500       510       520        

       520       530       540       550       560         570     
pF1KSD CELLRWKENPSPENRTLWENLCTIRRFLNLPQHERDVIYEEESR--HHHSERMQHVVQLP
       ::::::::.::::::::::::  :::::.::: :::.:::.::   :::..:  :....:
NP_002 CELLRWKEDPSPENRTLWENLSMIRRFLSLPQPERDAIYEQESNAVHHHGDRPPHIIHVP
      530       540       550       560       570       580        

         580       590          600              610               
pF1KSD PEPVQVLHRQQSQPAKESS---PPREEAPP---P--PP--PTEDSCA-------KKPRSR
        : .:  ..::.:  ....   ::. .  :   :  ::  ::  : :       .: : :
NP_002 AEQIQQQQQQQQQQQQQQQAPPPPQPQQQPQTGPRLPPRQPTVASPAESDEENRQKTRPR
      590       600       610       620       630       640        

      620       630       640       650       660       670        
pF1KSD TKISLEALGILQSFIHDVGLYPDQEAIHTLSAQLDLPKHTIIKFFQNQRYHVKHHGKLKE
       ::::.::::::::::.:::::::.:::.::::::::::.:::::::::::..:::::::.
NP_002 TKISVEALGILQSFIQDVGLYPDEEAIQTLSAQLDLPKYTIIKFFQNQRYYLKHHGKLKD
      650       660       670       680       690       700        

      680       690       700       710       720       730   
pF1KSD HLGSAVDVAEYKDEELLTESEENDSEEGSEEMYKVEAEEENADKSKAAPAEIDQR
       . :  :::::::.:::: . ::. ...... ...:. :::               
NP_002 NSGLEVDVAEYKEEELLKDLEESVQDKNTNTLFSVKLEEELSVEGNTDINTDLKD
      710       720       730       740       750       760   

>>NP_001309803 (OMIM: 602075) DNA-binding protein SATB1   (763 aa)
 initn: 2339 init1: 1042 opt: 2371  Z-score: 1767.2  bits: 337.7 E(85289): 1.1e-91
Smith-Waterman score: 2873; 62.1% identity (80.4% similar) in 760 aa overlap (1-718:1-748)

               10        20        30        40        50          
pF1KSD MERRSESPCLRDSPDRRSGSPDVKGPPPVKVARLEQNGSPMGARGRPNGAVAKAVG----
       :.. .:.   ..  .  ..  : :::: .:.:::::::::.: ::: ... ::  :    
NP_001 MDHLNEATQGKEHSEMSNNVSDPKGPP-AKIARLEQNGSPLG-RGRLGSTGAKMQGVPLK
               10        20         30        40         50        

                     60        70        80        90       100    
pF1KSD ------------GLMIPVFCVVEQLDGSLEYDNREEHAEFVLVRKDVLFSQLVETALLAL
                   : :.:::::::. ....::: .::::::::::::.::.::.: :::.:
NP_001 HSGHLMKTNLRKGTMLPVFCVVEHYENAIEYDCKEEHAEFVLVRKDMLFNQLIEMALLSL
       60        70        80        90       100       110        

          110       120       130       140       150       160    
pF1KSD GYSHSSAAQAQGIIKLGRWNPLPLSYVTDAPDATVADMLQDVYHVVTLKIQLQSCSKLED
       ::::::::::.:.:..:.:::.::::::::::::::::::::::::::::::.:: ::::
NP_001 GYSHSSAAQAKGLIQVGKWNPVPLSYVTDAPDATVADMLQDVYHVVTLKIQLHSCPKLED
      120       130       140       150       160       170        

          170       180       190       200       210       220    
pF1KSD LPAEQWNHATVRNALKELLKEMNQSTLAKECPLSQSMISSIVNSTYYANVSATKCQEFGR
       :: :::.:.:::::::.:::.::::.::::::::::::::::::::::::::.:::::::
NP_001 LPPEQWSHTTVRNALKDLLKDMNQSSLAKECPLSQSMISSIVNSTYYANVSAAKCQEFGR
      180       190       200       210       220       230        

          230       240       250       260       270         280  
pF1KSD WYKKYKKIKVERVERENLSDYCVLGQRPMHLPNMNQLASLGKTNEQSPH-SQIHH-STP-
       :::..:: :   :: ..::.   :.:.  .  :..:    :.: :: :  .:. : : : 
NP_001 WYKHFKKTKDMMVEMDSLSE---LSQQGANHVNFGQQPVPGNTAEQPPSPAQLSHGSQPS
      240       250          260       270       280       290     

             290       300       310       320       330       340 
pF1KSD IRNQVPALQPIMSPGLLSPQLSPQLVRQQIAMAHLINQQIAVSRLLAHQHPQAINQQFLN
       .:. .: :.:    ::.:  .::::: ::..::.:.::: ::.::::.:   ..:::.::
NP_001 VRTPLPNLHP----GLVSTPISPQLVNQQLVMAQLLNQQYAVNRLLAQQ---SLNQQYLN
         300           310       320       330       340           

               350         360       370       380       390       
pF1KSD HPP-IPRAV-KP--EPTNSSVEVSPDIYQQVRDELKRASVSQAVFARVAFNRTQGLLSEI
       ::: . :.. ::  . .....::: .::: ::::::::..::::::::::::::::::::
NP_001 HPPPVSRSMNKPLEQQVSTNTEVSSEIYQWVRDELKRAGISQAVFARVAFNRTQGLLSEI
      350       360       370       380       390       400        

       400       410       420       430       440       450       
pF1KSD LRKEEDPRTASQSLLVNLRAMQNFLNLPEVERDRIYQDERERSMNPNVSMVSSASSSPSS
       :::::::.:::::::::::::::::.:::.:::::::::::::.:   .:  .   :   
NP_001 LRKEEDPKTASQSLLVNLRAMQNFLQLPEAERDRIYQDERERSLNAASAMGPAPLISTPP
      410       420       430       440       450       460        

       460       470       480       490       500       510       
pF1KSD SRTPQAKTSTPTTDLPIKVDGANINITAAIYDEIQQEMKRAKVSQALFAKVAANKSQGWL
       :: ::.::.: .:.   : .. ..::.:.::::::::::::::::::::::::.::::::
NP_001 SRPPQVKTATIATERNGKPENNTMNINASIYDEIQQEMKRAKVSQALFAKVAATKSQGWL
      470       480       490       500       510       520        

       520       530       540       550       560         570     
pF1KSD CELLRWKENPSPENRTLWENLCTIRRFLNLPQHERDVIYEEESR--HHHSERMQHVVQLP
       ::::::::.::::::::::::  :::::.::: :::.:::.::   :::..:  :....:
NP_001 CELLRWKEDPSPENRTLWENLSMIRRFLSLPQPERDAIYEQESNAVHHHGDRPPHIIHVP
      530       540       550       560       570       580        

         580       590          600              610               
pF1KSD PEPVQVLHRQQSQPAKESS---PPREEAPP---P--PP--PTEDSCA-------KKPRSR
        : .:  ..::.:  ....   ::. .  :   :  ::  ::  : :       .: : :
NP_001 AEQIQQQQQQQQQQQQQQQAPPPPQPQQQPQTGPRLPPRQPTVASPAESDEENRQKTRPR
      590       600       610       620       630       640        

      620       630       640       650       660       670        
pF1KSD TKISLEALGILQSFIHDVGLYPDQEAIHTLSAQLDLPKHTIIKFFQNQRYHVKHHGKLKE
       ::::.::::::::::.:::::::.:::.::::::::::.:::::::::::..:::::::.
NP_001 TKISVEALGILQSFIQDVGLYPDEEAIQTLSAQLDLPKYTIIKFFQNQRYYLKHHGKLKD
      650       660       670       680       690       700        

      680       690       700       710       720       730   
pF1KSD HLGSAVDVAEYKDEELLTESEENDSEEGSEEMYKVEAEEENADKSKAAPAEIDQR
       . :  :::::::.:::: . ::. ...... ...:. :::               
NP_001 NSGLEVDVAEYKEEELLKDLEESVQDKNTNTLFSVKLEEELSVEGNTDINTDLKD
      710       720       730       740       750       760   




733 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 04:41:09 2016 done: Thu Nov  3 04:41:11 2016
 Total Scan time: 12.020 Total Display time:  0.220

Function used was FASTA [36.3.4 Apr, 2011]
Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.com