Result of FASTA (omim) for pF1KSDA0886
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KSDA0886, 1192 aa
  1>>>pF1KSDA0886 1192 - 1192 aa - 1192 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 15.6766+/-0.000528; mu= -23.4722+/- 0.033
 mean_var=703.6046+/-143.711, 0's: 0 Z-trim(123.2): 41  B-trim: 0 in 0/62
 Lambda= 0.048351
 statistics sampled from 42663 (42704) to 42663 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.758), E-opt: 0.2 (0.501), width:  16
 Scan time: 14.280

The best scores are:                                      opt bits E(85289)
NP_065393 (OMIM: 604475) reticulon-4 isoform A [Ho (1192) 7621 547.8 1.5e-154
NP_001308790 (OMIM: 604475) reticulon-4 isoform E  ( 986) 6195 448.2 1.2e-124
XP_005264491 (OMIM: 604475) PREDICTED: reticulon-4 ( 986) 6195 448.2 1.2e-124
NP_001308788 (OMIM: 604475) reticulon-4 isoform E  ( 986) 6195 448.2 1.2e-124
NP_001308791 (OMIM: 604475) reticulon-4 isoform E  ( 986) 6195 448.2 1.2e-124
XP_016860007 (OMIM: 604475) PREDICTED: reticulon-4 ( 986) 6195 448.2 1.2e-124
NP_001308833 (OMIM: 604475) reticulon-4 isoform E  ( 986) 6195 448.2 1.2e-124
XP_016860008 (OMIM: 604475) PREDICTED: reticulon-4 ( 986) 6195 448.2 1.2e-124
NP_001308789 (OMIM: 604475) reticulon-4 isoform E  ( 986) 6195 448.2 1.2e-124
NP_001308792 (OMIM: 604475) reticulon-4 isoform E  ( 986) 6195 448.2 1.2e-124
NP_997404 (OMIM: 604475) reticulon-4 isoform E [Ho ( 986) 6195 448.2 1.2e-124
NP_997403 (OMIM: 604475) reticulon-4 isoform D [Ho ( 392) 1413 114.3 1.5e-24
NP_722550 (OMIM: 604475) reticulon-4 isoform B [Ho ( 373) 1298 106.3 3.8e-22
NP_008939 (OMIM: 604475) reticulon-4 isoform C [Ho ( 199) 1174 97.4 9.5e-20
NP_066959 (OMIM: 600865) reticulon-1 isoform A [Ho ( 776)  922 80.3 5.2e-14
NP_996734 (OMIM: 600865) reticulon-1 isoform C [Ho ( 208)  873 76.4 2.1e-13
XP_016877067 (OMIM: 600865) PREDICTED: reticulon-1 ( 193)  865 75.9 2.9e-13
NP_006045 (OMIM: 604249) reticulon-3 isoform a [Ho ( 236)  795 71.1 9.8e-12
NP_958832 (OMIM: 604249) reticulon-3 isoform c [Ho ( 255)  793 70.9 1.1e-11
NP_001252519 (OMIM: 604249) reticulon-3 isoform f  ( 920)  801 71.9 2.1e-11
NP_958831 (OMIM: 604249) reticulon-3 isoform b [Ho (1013)  801 72.0 2.2e-11
NP_001252518 (OMIM: 604249) reticulon-3 isoform e  (1032)  801 72.0 2.2e-11
NP_958833 (OMIM: 604249) reticulon-3 isoform d [Ho ( 241)  673 62.5 3.6e-09
XP_011543033 (OMIM: 604249) PREDICTED: reticulon-3 ( 260)  671 62.4 4.2e-09
XP_011543032 (OMIM: 604249) PREDICTED: reticulon-3 (1037)  679 63.5 8.2e-09
NP_996783 (OMIM: 603183,604805) reticulon-2 isofor ( 472)  626 59.5 5.9e-08
NP_996784 (OMIM: 603183,604805) reticulon-2 isofor ( 205)  608 58.0 7.4e-08
NP_005610 (OMIM: 603183,604805) reticulon-2 isofor ( 545)  620 59.1 8.7e-08


>>NP_065393 (OMIM: 604475) reticulon-4 isoform A [Homo s  (1192 aa)
 initn: 7621 init1: 7621 opt: 7621  Z-score: 2895.5  bits: 547.8 E(85289): 1.5e-154
Smith-Waterman score: 7621; 100.0% identity (100.0% similar) in 1192 aa overlap (1-1192:1-1192)

               10        20        30        40        50        60
pF1KSD MEDLDQSPLVSSSDSPPRPQPAFKYQFVREPEDEEEEEEEEEEDEDEDLEELEVLERKPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 MEDLDQSPLVSSSDSPPRPQPAFKYQFVREPEDEEEEEEEEEEDEDEDLEELEVLERKPA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD AGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 AGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAP
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD SPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTPPAPAPAAPPSTPAAPKRRG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 SPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTPPAPAPAAPPSTPAAPKRRG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD SSGSVDETLFALPAASEPVIRSSAENMDLKEQPGNTISAGQEDFPSVLLETAASLPSLSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 SSGSVDETLFALPAASEPVIRSSAENMDLKEQPGNTISAGQEDFPSVLLETAASLPSLSP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD LSAASFKEHEYLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELEYSEM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LSAASFKEHEYLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELEYSEM
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD GSSFSVSPKAESAVIVANPREEIIVKNKDEEEKLVSNNILHNQQELPTALTKLVKEDEVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 GSSFSVSPKAESAVIVANPREEIIVKNKDEEEKLVSNNILHNQQELPTALTKLVKEDEVV
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD SSEKAKDSFNEKRVAVEAPMREEYADFKPFERVWEVKDSKEDSDMLAAGGKIESNLESKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 SSEKAKDSFNEKRVAVEAPMREEYADFKPFERVWEVKDSKEDSDMLAAGGKIESNLESKV
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD DKKCFADSLEQTNHEKDSESSNDDTSFPSTPEGIKDRSGAYITCAPFNPAATESIATNIF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 DKKCFADSLEQTNHEKDSESSNDDTSFPSTPEGIKDRSGAYITCAPFNPAATESIATNIF
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD PLLGDPTSENKTDEKKIEEKKAQIVTEKNTSTKTSNPFLVAAQDSETDYVTTDNLTKVTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 PLLGDPTSENKTDEKKIEEKKAQIVTEKNTSTKTSNPFLVAAQDSETDYVTTDNLTKVTE
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD EVVANMPEGLTPDLVQEACESELNEVTGTKIAYETKMDLVQTSEVMQESLYPAAQLCPSF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 EVVANMPEGLTPDLVQEACESELNEVTGTKIAYETKMDLVQTSEVMQESLYPAAQLCPSF
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD EESEATPSPVLPDIVMEAPLNSAVPSAGASVIQPSSSPLEASSVNYESIKHEPENPPPYE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 EESEATPSPVLPDIVMEAPLNSAVPSAGASVIQPSSSPLEASSVNYESIKHEPENPPPYE
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD EAMSVSLKKVSGIKEEIKEPENINAALQETEAPYISIACDLIKETKLSAEPAPDFSDYSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 EAMSVSLKKVSGIKEEIKEPENINAALQETEAPYISIACDLIKETKLSAEPAPDFSDYSE
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD MAKVEQPVPDHSELVEDSSPDSEPVDLFSDDSIPDVPQKQDETVMLVKESLTETSFESMI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 MAKVEQPVPDHSELVEDSSPDSEPVDLFSDDSIPDVPQKQDETVMLVKESLTETSFESMI
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KSD EYENKEKLSALPPEGGKPYLESFKLSLDNTKDTLLPDEVSTLSKKEKIPLQMEELSTAVY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 EYENKEKLSALPPEGGKPYLESFKLSLDNTKDTLLPDEVSTLSKKEKIPLQMEELSTAVY
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KSD SNDDLFISKEAQIRETETFSDSSPIEIIDEFPTLISSKTDSFSKLAREYTDLEVSHKSEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 SNDDLFISKEAQIRETETFSDSSPIEIIDEFPTLISSKTDSFSKLAREYTDLEVSHKSEI
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KSD ANAPDGAGSLPCTELPHDLSLKNIQPKVEEKISFSDDFSKNGSATSKVLLLPPDVSALAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 ANAPDGAGSLPCTELPHDLSLKNIQPKVEEKISFSDDFSKNGSATSKVLLLPPDVSALAT
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KSD QAEIESIVKPKVLVKEAEKKLPSDTEKEDRSPSAIFSAELSKTSVVDLLYWRDIKKTGVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 QAEIESIVKPKVLVKEAEKKLPSDTEKEDRSPSAIFSAELSKTSVVDLLYWRDIKKTGVV
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KSD FGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAYLESE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 FGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAYLESE
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KSD VAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFNGLTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 VAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFNGLTL
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190  
pF1KSD LILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKAE
             1150      1160      1170      1180      1190  

>>NP_001308790 (OMIM: 604475) reticulon-4 isoform E [Hom  (986 aa)
 initn: 6195 init1: 6195 opt: 6195  Z-score: 2359.0  bits: 448.2 E(85289): 1.2e-124
Smith-Waterman score: 6195; 100.0% identity (100.0% similar) in 986 aa overlap (207-1192:1-986)

        180       190       200       210       220       230      
pF1KSD KRRGSSGSVDETLFALPAASEPVIRSSAENMDLKEQPGNTISAGQEDFPSVLLETAASLP
                                     ::::::::::::::::::::::::::::::
NP_001                               MDLKEQPGNTISAGQEDFPSVLLETAASLP
                                             10        20        30

        240       250       260       270       280       290      
pF1KSD SLSPLSAASFKEHEYLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLSPLSAASFKEHEYLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE
               40        50        60        70        80        90

        300       310       320       330       340       350      
pF1KSD YSEMGSSFSVSPKAESAVIVANPREEIIVKNKDEEEKLVSNNILHNQQELPTALTKLVKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YSEMGSSFSVSPKAESAVIVANPREEIIVKNKDEEEKLVSNNILHNQQELPTALTKLVKE
              100       110       120       130       140       150

        360       370       380       390       400       410      
pF1KSD DEVVSSEKAKDSFNEKRVAVEAPMREEYADFKPFERVWEVKDSKEDSDMLAAGGKIESNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DEVVSSEKAKDSFNEKRVAVEAPMREEYADFKPFERVWEVKDSKEDSDMLAAGGKIESNL
              160       170       180       190       200       210

        420       430       440       450       460       470      
pF1KSD ESKVDKKCFADSLEQTNHEKDSESSNDDTSFPSTPEGIKDRSGAYITCAPFNPAATESIA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESKVDKKCFADSLEQTNHEKDSESSNDDTSFPSTPEGIKDRSGAYITCAPFNPAATESIA
              220       230       240       250       260       270

        480       490       500       510       520       530      
pF1KSD TNIFPLLGDPTSENKTDEKKIEEKKAQIVTEKNTSTKTSNPFLVAAQDSETDYVTTDNLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TNIFPLLGDPTSENKTDEKKIEEKKAQIVTEKNTSTKTSNPFLVAAQDSETDYVTTDNLT
              280       290       300       310       320       330

        540       550       560       570       580       590      
pF1KSD KVTEEVVANMPEGLTPDLVQEACESELNEVTGTKIAYETKMDLVQTSEVMQESLYPAAQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVTEEVVANMPEGLTPDLVQEACESELNEVTGTKIAYETKMDLVQTSEVMQESLYPAAQL
              340       350       360       370       380       390

        600       610       620       630       640       650      
pF1KSD CPSFEESEATPSPVLPDIVMEAPLNSAVPSAGASVIQPSSSPLEASSVNYESIKHEPENP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CPSFEESEATPSPVLPDIVMEAPLNSAVPSAGASVIQPSSSPLEASSVNYESIKHEPENP
              400       410       420       430       440       450

        660       670       680       690       700       710      
pF1KSD PPYEEAMSVSLKKVSGIKEEIKEPENINAALQETEAPYISIACDLIKETKLSAEPAPDFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPYEEAMSVSLKKVSGIKEEIKEPENINAALQETEAPYISIACDLIKETKLSAEPAPDFS
              460       470       480       490       500       510

        720       730       740       750       760       770      
pF1KSD DYSEMAKVEQPVPDHSELVEDSSPDSEPVDLFSDDSIPDVPQKQDETVMLVKESLTETSF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DYSEMAKVEQPVPDHSELVEDSSPDSEPVDLFSDDSIPDVPQKQDETVMLVKESLTETSF
              520       530       540       550       560       570

        780       790       800       810       820       830      
pF1KSD ESMIEYENKEKLSALPPEGGKPYLESFKLSLDNTKDTLLPDEVSTLSKKEKIPLQMEELS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESMIEYENKEKLSALPPEGGKPYLESFKLSLDNTKDTLLPDEVSTLSKKEKIPLQMEELS
              580       590       600       610       620       630

        840       850       860       870       880       890      
pF1KSD TAVYSNDDLFISKEAQIRETETFSDSSPIEIIDEFPTLISSKTDSFSKLAREYTDLEVSH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TAVYSNDDLFISKEAQIRETETFSDSSPIEIIDEFPTLISSKTDSFSKLAREYTDLEVSH
              640       650       660       670       680       690

        900       910       920       930       940       950      
pF1KSD KSEIANAPDGAGSLPCTELPHDLSLKNIQPKVEEKISFSDDFSKNGSATSKVLLLPPDVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSEIANAPDGAGSLPCTELPHDLSLKNIQPKVEEKISFSDDFSKNGSATSKVLLLPPDVS
              700       710       720       730       740       750

        960       970       980       990      1000      1010      
pF1KSD ALATQAEIESIVKPKVLVKEAEKKLPSDTEKEDRSPSAIFSAELSKTSVVDLLYWRDIKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALATQAEIESIVKPKVLVKEAEKKLPSDTEKEDRSPSAIFSAELSKTSVVDLLYWRDIKK
              760       770       780       790       800       810

       1020      1030      1040      1050      1060      1070      
pF1KSD TGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAY
              820       830       840       850       860       870

       1080      1090      1100      1110      1120      1130      
pF1KSD LESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFN
              880       890       900       910       920       930

       1140      1150      1160      1170      1180      1190  
pF1KSD GLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKAE
              940       950       960       970       980      

>>XP_005264491 (OMIM: 604475) PREDICTED: reticulon-4 iso  (986 aa)
 initn: 6195 init1: 6195 opt: 6195  Z-score: 2359.0  bits: 448.2 E(85289): 1.2e-124
Smith-Waterman score: 6195; 100.0% identity (100.0% similar) in 986 aa overlap (207-1192:1-986)

        180       190       200       210       220       230      
pF1KSD KRRGSSGSVDETLFALPAASEPVIRSSAENMDLKEQPGNTISAGQEDFPSVLLETAASLP
                                     ::::::::::::::::::::::::::::::
XP_005                               MDLKEQPGNTISAGQEDFPSVLLETAASLP
                                             10        20        30

        240       250       260       270       280       290      
pF1KSD SLSPLSAASFKEHEYLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLSPLSAASFKEHEYLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE
               40        50        60        70        80        90

        300       310       320       330       340       350      
pF1KSD YSEMGSSFSVSPKAESAVIVANPREEIIVKNKDEEEKLVSNNILHNQQELPTALTKLVKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YSEMGSSFSVSPKAESAVIVANPREEIIVKNKDEEEKLVSNNILHNQQELPTALTKLVKE
              100       110       120       130       140       150

        360       370       380       390       400       410      
pF1KSD DEVVSSEKAKDSFNEKRVAVEAPMREEYADFKPFERVWEVKDSKEDSDMLAAGGKIESNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DEVVSSEKAKDSFNEKRVAVEAPMREEYADFKPFERVWEVKDSKEDSDMLAAGGKIESNL
              160       170       180       190       200       210

        420       430       440       450       460       470      
pF1KSD ESKVDKKCFADSLEQTNHEKDSESSNDDTSFPSTPEGIKDRSGAYITCAPFNPAATESIA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ESKVDKKCFADSLEQTNHEKDSESSNDDTSFPSTPEGIKDRSGAYITCAPFNPAATESIA
              220       230       240       250       260       270

        480       490       500       510       520       530      
pF1KSD TNIFPLLGDPTSENKTDEKKIEEKKAQIVTEKNTSTKTSNPFLVAAQDSETDYVTTDNLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TNIFPLLGDPTSENKTDEKKIEEKKAQIVTEKNTSTKTSNPFLVAAQDSETDYVTTDNLT
              280       290       300       310       320       330

        540       550       560       570       580       590      
pF1KSD KVTEEVVANMPEGLTPDLVQEACESELNEVTGTKIAYETKMDLVQTSEVMQESLYPAAQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KVTEEVVANMPEGLTPDLVQEACESELNEVTGTKIAYETKMDLVQTSEVMQESLYPAAQL
              340       350       360       370       380       390

        600       610       620       630       640       650      
pF1KSD CPSFEESEATPSPVLPDIVMEAPLNSAVPSAGASVIQPSSSPLEASSVNYESIKHEPENP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CPSFEESEATPSPVLPDIVMEAPLNSAVPSAGASVIQPSSSPLEASSVNYESIKHEPENP
              400       410       420       430       440       450

        660       670       680       690       700       710      
pF1KSD PPYEEAMSVSLKKVSGIKEEIKEPENINAALQETEAPYISIACDLIKETKLSAEPAPDFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PPYEEAMSVSLKKVSGIKEEIKEPENINAALQETEAPYISIACDLIKETKLSAEPAPDFS
              460       470       480       490       500       510

        720       730       740       750       760       770      
pF1KSD DYSEMAKVEQPVPDHSELVEDSSPDSEPVDLFSDDSIPDVPQKQDETVMLVKESLTETSF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DYSEMAKVEQPVPDHSELVEDSSPDSEPVDLFSDDSIPDVPQKQDETVMLVKESLTETSF
              520       530       540       550       560       570

        780       790       800       810       820       830      
pF1KSD ESMIEYENKEKLSALPPEGGKPYLESFKLSLDNTKDTLLPDEVSTLSKKEKIPLQMEELS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ESMIEYENKEKLSALPPEGGKPYLESFKLSLDNTKDTLLPDEVSTLSKKEKIPLQMEELS
              580       590       600       610       620       630

        840       850       860       870       880       890      
pF1KSD TAVYSNDDLFISKEAQIRETETFSDSSPIEIIDEFPTLISSKTDSFSKLAREYTDLEVSH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TAVYSNDDLFISKEAQIRETETFSDSSPIEIIDEFPTLISSKTDSFSKLAREYTDLEVSH
              640       650       660       670       680       690

        900       910       920       930       940       950      
pF1KSD KSEIANAPDGAGSLPCTELPHDLSLKNIQPKVEEKISFSDDFSKNGSATSKVLLLPPDVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KSEIANAPDGAGSLPCTELPHDLSLKNIQPKVEEKISFSDDFSKNGSATSKVLLLPPDVS
              700       710       720       730       740       750

        960       970       980       990      1000      1010      
pF1KSD ALATQAEIESIVKPKVLVKEAEKKLPSDTEKEDRSPSAIFSAELSKTSVVDLLYWRDIKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ALATQAEIESIVKPKVLVKEAEKKLPSDTEKEDRSPSAIFSAELSKTSVVDLLYWRDIKK
              760       770       780       790       800       810

       1020      1030      1040      1050      1060      1070      
pF1KSD TGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAY
              820       830       840       850       860       870

       1080      1090      1100      1110      1120      1130      
pF1KSD LESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFN
              880       890       900       910       920       930

       1140      1150      1160      1170      1180      1190  
pF1KSD GLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKAE
              940       950       960       970       980      

>>NP_001308788 (OMIM: 604475) reticulon-4 isoform E [Hom  (986 aa)
 initn: 6195 init1: 6195 opt: 6195  Z-score: 2359.0  bits: 448.2 E(85289): 1.2e-124
Smith-Waterman score: 6195; 100.0% identity (100.0% similar) in 986 aa overlap (207-1192:1-986)

        180       190       200       210       220       230      
pF1KSD KRRGSSGSVDETLFALPAASEPVIRSSAENMDLKEQPGNTISAGQEDFPSVLLETAASLP
                                     ::::::::::::::::::::::::::::::
NP_001                               MDLKEQPGNTISAGQEDFPSVLLETAASLP
                                             10        20        30

        240       250       260       270       280       290      
pF1KSD SLSPLSAASFKEHEYLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLSPLSAASFKEHEYLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE
               40        50        60        70        80        90

        300       310       320       330       340       350      
pF1KSD YSEMGSSFSVSPKAESAVIVANPREEIIVKNKDEEEKLVSNNILHNQQELPTALTKLVKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YSEMGSSFSVSPKAESAVIVANPREEIIVKNKDEEEKLVSNNILHNQQELPTALTKLVKE
              100       110       120       130       140       150

        360       370       380       390       400       410      
pF1KSD DEVVSSEKAKDSFNEKRVAVEAPMREEYADFKPFERVWEVKDSKEDSDMLAAGGKIESNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DEVVSSEKAKDSFNEKRVAVEAPMREEYADFKPFERVWEVKDSKEDSDMLAAGGKIESNL
              160       170       180       190       200       210

        420       430       440       450       460       470      
pF1KSD ESKVDKKCFADSLEQTNHEKDSESSNDDTSFPSTPEGIKDRSGAYITCAPFNPAATESIA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESKVDKKCFADSLEQTNHEKDSESSNDDTSFPSTPEGIKDRSGAYITCAPFNPAATESIA
              220       230       240       250       260       270

        480       490       500       510       520       530      
pF1KSD TNIFPLLGDPTSENKTDEKKIEEKKAQIVTEKNTSTKTSNPFLVAAQDSETDYVTTDNLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TNIFPLLGDPTSENKTDEKKIEEKKAQIVTEKNTSTKTSNPFLVAAQDSETDYVTTDNLT
              280       290       300       310       320       330

        540       550       560       570       580       590      
pF1KSD KVTEEVVANMPEGLTPDLVQEACESELNEVTGTKIAYETKMDLVQTSEVMQESLYPAAQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVTEEVVANMPEGLTPDLVQEACESELNEVTGTKIAYETKMDLVQTSEVMQESLYPAAQL
              340       350       360       370       380       390

        600       610       620       630       640       650      
pF1KSD CPSFEESEATPSPVLPDIVMEAPLNSAVPSAGASVIQPSSSPLEASSVNYESIKHEPENP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CPSFEESEATPSPVLPDIVMEAPLNSAVPSAGASVIQPSSSPLEASSVNYESIKHEPENP
              400       410       420       430       440       450

        660       670       680       690       700       710      
pF1KSD PPYEEAMSVSLKKVSGIKEEIKEPENINAALQETEAPYISIACDLIKETKLSAEPAPDFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPYEEAMSVSLKKVSGIKEEIKEPENINAALQETEAPYISIACDLIKETKLSAEPAPDFS
              460       470       480       490       500       510

        720       730       740       750       760       770      
pF1KSD DYSEMAKVEQPVPDHSELVEDSSPDSEPVDLFSDDSIPDVPQKQDETVMLVKESLTETSF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DYSEMAKVEQPVPDHSELVEDSSPDSEPVDLFSDDSIPDVPQKQDETVMLVKESLTETSF
              520       530       540       550       560       570

        780       790       800       810       820       830      
pF1KSD ESMIEYENKEKLSALPPEGGKPYLESFKLSLDNTKDTLLPDEVSTLSKKEKIPLQMEELS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESMIEYENKEKLSALPPEGGKPYLESFKLSLDNTKDTLLPDEVSTLSKKEKIPLQMEELS
              580       590       600       610       620       630

        840       850       860       870       880       890      
pF1KSD TAVYSNDDLFISKEAQIRETETFSDSSPIEIIDEFPTLISSKTDSFSKLAREYTDLEVSH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TAVYSNDDLFISKEAQIRETETFSDSSPIEIIDEFPTLISSKTDSFSKLAREYTDLEVSH
              640       650       660       670       680       690

        900       910       920       930       940       950      
pF1KSD KSEIANAPDGAGSLPCTELPHDLSLKNIQPKVEEKISFSDDFSKNGSATSKVLLLPPDVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSEIANAPDGAGSLPCTELPHDLSLKNIQPKVEEKISFSDDFSKNGSATSKVLLLPPDVS
              700       710       720       730       740       750

        960       970       980       990      1000      1010      
pF1KSD ALATQAEIESIVKPKVLVKEAEKKLPSDTEKEDRSPSAIFSAELSKTSVVDLLYWRDIKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALATQAEIESIVKPKVLVKEAEKKLPSDTEKEDRSPSAIFSAELSKTSVVDLLYWRDIKK
              760       770       780       790       800       810

       1020      1030      1040      1050      1060      1070      
pF1KSD TGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAY
              820       830       840       850       860       870

       1080      1090      1100      1110      1120      1130      
pF1KSD LESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFN
              880       890       900       910       920       930

       1140      1150      1160      1170      1180      1190  
pF1KSD GLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKAE
              940       950       960       970       980      

>>NP_001308791 (OMIM: 604475) reticulon-4 isoform E [Hom  (986 aa)
 initn: 6195 init1: 6195 opt: 6195  Z-score: 2359.0  bits: 448.2 E(85289): 1.2e-124
Smith-Waterman score: 6195; 100.0% identity (100.0% similar) in 986 aa overlap (207-1192:1-986)

        180       190       200       210       220       230      
pF1KSD KRRGSSGSVDETLFALPAASEPVIRSSAENMDLKEQPGNTISAGQEDFPSVLLETAASLP
                                     ::::::::::::::::::::::::::::::
NP_001                               MDLKEQPGNTISAGQEDFPSVLLETAASLP
                                             10        20        30

        240       250       260       270       280       290      
pF1KSD SLSPLSAASFKEHEYLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLSPLSAASFKEHEYLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE
               40        50        60        70        80        90

        300       310       320       330       340       350      
pF1KSD YSEMGSSFSVSPKAESAVIVANPREEIIVKNKDEEEKLVSNNILHNQQELPTALTKLVKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YSEMGSSFSVSPKAESAVIVANPREEIIVKNKDEEEKLVSNNILHNQQELPTALTKLVKE
              100       110       120       130       140       150

        360       370       380       390       400       410      
pF1KSD DEVVSSEKAKDSFNEKRVAVEAPMREEYADFKPFERVWEVKDSKEDSDMLAAGGKIESNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DEVVSSEKAKDSFNEKRVAVEAPMREEYADFKPFERVWEVKDSKEDSDMLAAGGKIESNL
              160       170       180       190       200       210

        420       430       440       450       460       470      
pF1KSD ESKVDKKCFADSLEQTNHEKDSESSNDDTSFPSTPEGIKDRSGAYITCAPFNPAATESIA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESKVDKKCFADSLEQTNHEKDSESSNDDTSFPSTPEGIKDRSGAYITCAPFNPAATESIA
              220       230       240       250       260       270

        480       490       500       510       520       530      
pF1KSD TNIFPLLGDPTSENKTDEKKIEEKKAQIVTEKNTSTKTSNPFLVAAQDSETDYVTTDNLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TNIFPLLGDPTSENKTDEKKIEEKKAQIVTEKNTSTKTSNPFLVAAQDSETDYVTTDNLT
              280       290       300       310       320       330

        540       550       560       570       580       590      
pF1KSD KVTEEVVANMPEGLTPDLVQEACESELNEVTGTKIAYETKMDLVQTSEVMQESLYPAAQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVTEEVVANMPEGLTPDLVQEACESELNEVTGTKIAYETKMDLVQTSEVMQESLYPAAQL
              340       350       360       370       380       390

        600       610       620       630       640       650      
pF1KSD CPSFEESEATPSPVLPDIVMEAPLNSAVPSAGASVIQPSSSPLEASSVNYESIKHEPENP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CPSFEESEATPSPVLPDIVMEAPLNSAVPSAGASVIQPSSSPLEASSVNYESIKHEPENP
              400       410       420       430       440       450

        660       670       680       690       700       710      
pF1KSD PPYEEAMSVSLKKVSGIKEEIKEPENINAALQETEAPYISIACDLIKETKLSAEPAPDFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPYEEAMSVSLKKVSGIKEEIKEPENINAALQETEAPYISIACDLIKETKLSAEPAPDFS
              460       470       480       490       500       510

        720       730       740       750       760       770      
pF1KSD DYSEMAKVEQPVPDHSELVEDSSPDSEPVDLFSDDSIPDVPQKQDETVMLVKESLTETSF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DYSEMAKVEQPVPDHSELVEDSSPDSEPVDLFSDDSIPDVPQKQDETVMLVKESLTETSF
              520       530       540       550       560       570

        780       790       800       810       820       830      
pF1KSD ESMIEYENKEKLSALPPEGGKPYLESFKLSLDNTKDTLLPDEVSTLSKKEKIPLQMEELS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESMIEYENKEKLSALPPEGGKPYLESFKLSLDNTKDTLLPDEVSTLSKKEKIPLQMEELS
              580       590       600       610       620       630

        840       850       860       870       880       890      
pF1KSD TAVYSNDDLFISKEAQIRETETFSDSSPIEIIDEFPTLISSKTDSFSKLAREYTDLEVSH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TAVYSNDDLFISKEAQIRETETFSDSSPIEIIDEFPTLISSKTDSFSKLAREYTDLEVSH
              640       650       660       670       680       690

        900       910       920       930       940       950      
pF1KSD KSEIANAPDGAGSLPCTELPHDLSLKNIQPKVEEKISFSDDFSKNGSATSKVLLLPPDVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSEIANAPDGAGSLPCTELPHDLSLKNIQPKVEEKISFSDDFSKNGSATSKVLLLPPDVS
              700       710       720       730       740       750

        960       970       980       990      1000      1010      
pF1KSD ALATQAEIESIVKPKVLVKEAEKKLPSDTEKEDRSPSAIFSAELSKTSVVDLLYWRDIKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALATQAEIESIVKPKVLVKEAEKKLPSDTEKEDRSPSAIFSAELSKTSVVDLLYWRDIKK
              760       770       780       790       800       810

       1020      1030      1040      1050      1060      1070      
pF1KSD TGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAY
              820       830       840       850       860       870

       1080      1090      1100      1110      1120      1130      
pF1KSD LESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFN
              880       890       900       910       920       930

       1140      1150      1160      1170      1180      1190  
pF1KSD GLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKAE
              940       950       960       970       980      

>>XP_016860007 (OMIM: 604475) PREDICTED: reticulon-4 iso  (986 aa)
 initn: 6195 init1: 6195 opt: 6195  Z-score: 2359.0  bits: 448.2 E(85289): 1.2e-124
Smith-Waterman score: 6195; 100.0% identity (100.0% similar) in 986 aa overlap (207-1192:1-986)

        180       190       200       210       220       230      
pF1KSD KRRGSSGSVDETLFALPAASEPVIRSSAENMDLKEQPGNTISAGQEDFPSVLLETAASLP
                                     ::::::::::::::::::::::::::::::
XP_016                               MDLKEQPGNTISAGQEDFPSVLLETAASLP
                                             10        20        30

        240       250       260       270       280       290      
pF1KSD SLSPLSAASFKEHEYLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLSPLSAASFKEHEYLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE
               40        50        60        70        80        90

        300       310       320       330       340       350      
pF1KSD YSEMGSSFSVSPKAESAVIVANPREEIIVKNKDEEEKLVSNNILHNQQELPTALTKLVKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YSEMGSSFSVSPKAESAVIVANPREEIIVKNKDEEEKLVSNNILHNQQELPTALTKLVKE
              100       110       120       130       140       150

        360       370       380       390       400       410      
pF1KSD DEVVSSEKAKDSFNEKRVAVEAPMREEYADFKPFERVWEVKDSKEDSDMLAAGGKIESNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DEVVSSEKAKDSFNEKRVAVEAPMREEYADFKPFERVWEVKDSKEDSDMLAAGGKIESNL
              160       170       180       190       200       210

        420       430       440       450       460       470      
pF1KSD ESKVDKKCFADSLEQTNHEKDSESSNDDTSFPSTPEGIKDRSGAYITCAPFNPAATESIA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESKVDKKCFADSLEQTNHEKDSESSNDDTSFPSTPEGIKDRSGAYITCAPFNPAATESIA
              220       230       240       250       260       270

        480       490       500       510       520       530      
pF1KSD TNIFPLLGDPTSENKTDEKKIEEKKAQIVTEKNTSTKTSNPFLVAAQDSETDYVTTDNLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TNIFPLLGDPTSENKTDEKKIEEKKAQIVTEKNTSTKTSNPFLVAAQDSETDYVTTDNLT
              280       290       300       310       320       330

        540       550       560       570       580       590      
pF1KSD KVTEEVVANMPEGLTPDLVQEACESELNEVTGTKIAYETKMDLVQTSEVMQESLYPAAQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVTEEVVANMPEGLTPDLVQEACESELNEVTGTKIAYETKMDLVQTSEVMQESLYPAAQL
              340       350       360       370       380       390

        600       610       620       630       640       650      
pF1KSD CPSFEESEATPSPVLPDIVMEAPLNSAVPSAGASVIQPSSSPLEASSVNYESIKHEPENP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CPSFEESEATPSPVLPDIVMEAPLNSAVPSAGASVIQPSSSPLEASSVNYESIKHEPENP
              400       410       420       430       440       450

        660       670       680       690       700       710      
pF1KSD PPYEEAMSVSLKKVSGIKEEIKEPENINAALQETEAPYISIACDLIKETKLSAEPAPDFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPYEEAMSVSLKKVSGIKEEIKEPENINAALQETEAPYISIACDLIKETKLSAEPAPDFS
              460       470       480       490       500       510

        720       730       740       750       760       770      
pF1KSD DYSEMAKVEQPVPDHSELVEDSSPDSEPVDLFSDDSIPDVPQKQDETVMLVKESLTETSF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DYSEMAKVEQPVPDHSELVEDSSPDSEPVDLFSDDSIPDVPQKQDETVMLVKESLTETSF
              520       530       540       550       560       570

        780       790       800       810       820       830      
pF1KSD ESMIEYENKEKLSALPPEGGKPYLESFKLSLDNTKDTLLPDEVSTLSKKEKIPLQMEELS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESMIEYENKEKLSALPPEGGKPYLESFKLSLDNTKDTLLPDEVSTLSKKEKIPLQMEELS
              580       590       600       610       620       630

        840       850       860       870       880       890      
pF1KSD TAVYSNDDLFISKEAQIRETETFSDSSPIEIIDEFPTLISSKTDSFSKLAREYTDLEVSH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TAVYSNDDLFISKEAQIRETETFSDSSPIEIIDEFPTLISSKTDSFSKLAREYTDLEVSH
              640       650       660       670       680       690

        900       910       920       930       940       950      
pF1KSD KSEIANAPDGAGSLPCTELPHDLSLKNIQPKVEEKISFSDDFSKNGSATSKVLLLPPDVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSEIANAPDGAGSLPCTELPHDLSLKNIQPKVEEKISFSDDFSKNGSATSKVLLLPPDVS
              700       710       720       730       740       750

        960       970       980       990      1000      1010      
pF1KSD ALATQAEIESIVKPKVLVKEAEKKLPSDTEKEDRSPSAIFSAELSKTSVVDLLYWRDIKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALATQAEIESIVKPKVLVKEAEKKLPSDTEKEDRSPSAIFSAELSKTSVVDLLYWRDIKK
              760       770       780       790       800       810

       1020      1030      1040      1050      1060      1070      
pF1KSD TGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAY
              820       830       840       850       860       870

       1080      1090      1100      1110      1120      1130      
pF1KSD LESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFN
              880       890       900       910       920       930

       1140      1150      1160      1170      1180      1190  
pF1KSD GLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKAE
              940       950       960       970       980      

>>NP_001308833 (OMIM: 604475) reticulon-4 isoform E [Hom  (986 aa)
 initn: 6195 init1: 6195 opt: 6195  Z-score: 2359.0  bits: 448.2 E(85289): 1.2e-124
Smith-Waterman score: 6195; 100.0% identity (100.0% similar) in 986 aa overlap (207-1192:1-986)

        180       190       200       210       220       230      
pF1KSD KRRGSSGSVDETLFALPAASEPVIRSSAENMDLKEQPGNTISAGQEDFPSVLLETAASLP
                                     ::::::::::::::::::::::::::::::
NP_001                               MDLKEQPGNTISAGQEDFPSVLLETAASLP
                                             10        20        30

        240       250       260       270       280       290      
pF1KSD SLSPLSAASFKEHEYLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLSPLSAASFKEHEYLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE
               40        50        60        70        80        90

        300       310       320       330       340       350      
pF1KSD YSEMGSSFSVSPKAESAVIVANPREEIIVKNKDEEEKLVSNNILHNQQELPTALTKLVKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YSEMGSSFSVSPKAESAVIVANPREEIIVKNKDEEEKLVSNNILHNQQELPTALTKLVKE
              100       110       120       130       140       150

        360       370       380       390       400       410      
pF1KSD DEVVSSEKAKDSFNEKRVAVEAPMREEYADFKPFERVWEVKDSKEDSDMLAAGGKIESNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DEVVSSEKAKDSFNEKRVAVEAPMREEYADFKPFERVWEVKDSKEDSDMLAAGGKIESNL
              160       170       180       190       200       210

        420       430       440       450       460       470      
pF1KSD ESKVDKKCFADSLEQTNHEKDSESSNDDTSFPSTPEGIKDRSGAYITCAPFNPAATESIA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESKVDKKCFADSLEQTNHEKDSESSNDDTSFPSTPEGIKDRSGAYITCAPFNPAATESIA
              220       230       240       250       260       270

        480       490       500       510       520       530      
pF1KSD TNIFPLLGDPTSENKTDEKKIEEKKAQIVTEKNTSTKTSNPFLVAAQDSETDYVTTDNLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TNIFPLLGDPTSENKTDEKKIEEKKAQIVTEKNTSTKTSNPFLVAAQDSETDYVTTDNLT
              280       290       300       310       320       330

        540       550       560       570       580       590      
pF1KSD KVTEEVVANMPEGLTPDLVQEACESELNEVTGTKIAYETKMDLVQTSEVMQESLYPAAQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVTEEVVANMPEGLTPDLVQEACESELNEVTGTKIAYETKMDLVQTSEVMQESLYPAAQL
              340       350       360       370       380       390

        600       610       620       630       640       650      
pF1KSD CPSFEESEATPSPVLPDIVMEAPLNSAVPSAGASVIQPSSSPLEASSVNYESIKHEPENP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CPSFEESEATPSPVLPDIVMEAPLNSAVPSAGASVIQPSSSPLEASSVNYESIKHEPENP
              400       410       420       430       440       450

        660       670       680       690       700       710      
pF1KSD PPYEEAMSVSLKKVSGIKEEIKEPENINAALQETEAPYISIACDLIKETKLSAEPAPDFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPYEEAMSVSLKKVSGIKEEIKEPENINAALQETEAPYISIACDLIKETKLSAEPAPDFS
              460       470       480       490       500       510

        720       730       740       750       760       770      
pF1KSD DYSEMAKVEQPVPDHSELVEDSSPDSEPVDLFSDDSIPDVPQKQDETVMLVKESLTETSF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DYSEMAKVEQPVPDHSELVEDSSPDSEPVDLFSDDSIPDVPQKQDETVMLVKESLTETSF
              520       530       540       550       560       570

        780       790       800       810       820       830      
pF1KSD ESMIEYENKEKLSALPPEGGKPYLESFKLSLDNTKDTLLPDEVSTLSKKEKIPLQMEELS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESMIEYENKEKLSALPPEGGKPYLESFKLSLDNTKDTLLPDEVSTLSKKEKIPLQMEELS
              580       590       600       610       620       630

        840       850       860       870       880       890      
pF1KSD TAVYSNDDLFISKEAQIRETETFSDSSPIEIIDEFPTLISSKTDSFSKLAREYTDLEVSH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TAVYSNDDLFISKEAQIRETETFSDSSPIEIIDEFPTLISSKTDSFSKLAREYTDLEVSH
              640       650       660       670       680       690

        900       910       920       930       940       950      
pF1KSD KSEIANAPDGAGSLPCTELPHDLSLKNIQPKVEEKISFSDDFSKNGSATSKVLLLPPDVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSEIANAPDGAGSLPCTELPHDLSLKNIQPKVEEKISFSDDFSKNGSATSKVLLLPPDVS
              700       710       720       730       740       750

        960       970       980       990      1000      1010      
pF1KSD ALATQAEIESIVKPKVLVKEAEKKLPSDTEKEDRSPSAIFSAELSKTSVVDLLYWRDIKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALATQAEIESIVKPKVLVKEAEKKLPSDTEKEDRSPSAIFSAELSKTSVVDLLYWRDIKK
              760       770       780       790       800       810

       1020      1030      1040      1050      1060      1070      
pF1KSD TGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAY
              820       830       840       850       860       870

       1080      1090      1100      1110      1120      1130      
pF1KSD LESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFN
              880       890       900       910       920       930

       1140      1150      1160      1170      1180      1190  
pF1KSD GLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKAE
              940       950       960       970       980      

>>XP_016860008 (OMIM: 604475) PREDICTED: reticulon-4 iso  (986 aa)
 initn: 6195 init1: 6195 opt: 6195  Z-score: 2359.0  bits: 448.2 E(85289): 1.2e-124
Smith-Waterman score: 6195; 100.0% identity (100.0% similar) in 986 aa overlap (207-1192:1-986)

        180       190       200       210       220       230      
pF1KSD KRRGSSGSVDETLFALPAASEPVIRSSAENMDLKEQPGNTISAGQEDFPSVLLETAASLP
                                     ::::::::::::::::::::::::::::::
XP_016                               MDLKEQPGNTISAGQEDFPSVLLETAASLP
                                             10        20        30

        240       250       260       270       280       290      
pF1KSD SLSPLSAASFKEHEYLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLSPLSAASFKEHEYLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE
               40        50        60        70        80        90

        300       310       320       330       340       350      
pF1KSD YSEMGSSFSVSPKAESAVIVANPREEIIVKNKDEEEKLVSNNILHNQQELPTALTKLVKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YSEMGSSFSVSPKAESAVIVANPREEIIVKNKDEEEKLVSNNILHNQQELPTALTKLVKE
              100       110       120       130       140       150

        360       370       380       390       400       410      
pF1KSD DEVVSSEKAKDSFNEKRVAVEAPMREEYADFKPFERVWEVKDSKEDSDMLAAGGKIESNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DEVVSSEKAKDSFNEKRVAVEAPMREEYADFKPFERVWEVKDSKEDSDMLAAGGKIESNL
              160       170       180       190       200       210

        420       430       440       450       460       470      
pF1KSD ESKVDKKCFADSLEQTNHEKDSESSNDDTSFPSTPEGIKDRSGAYITCAPFNPAATESIA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESKVDKKCFADSLEQTNHEKDSESSNDDTSFPSTPEGIKDRSGAYITCAPFNPAATESIA
              220       230       240       250       260       270

        480       490       500       510       520       530      
pF1KSD TNIFPLLGDPTSENKTDEKKIEEKKAQIVTEKNTSTKTSNPFLVAAQDSETDYVTTDNLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TNIFPLLGDPTSENKTDEKKIEEKKAQIVTEKNTSTKTSNPFLVAAQDSETDYVTTDNLT
              280       290       300       310       320       330

        540       550       560       570       580       590      
pF1KSD KVTEEVVANMPEGLTPDLVQEACESELNEVTGTKIAYETKMDLVQTSEVMQESLYPAAQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVTEEVVANMPEGLTPDLVQEACESELNEVTGTKIAYETKMDLVQTSEVMQESLYPAAQL
              340       350       360       370       380       390

        600       610       620       630       640       650      
pF1KSD CPSFEESEATPSPVLPDIVMEAPLNSAVPSAGASVIQPSSSPLEASSVNYESIKHEPENP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CPSFEESEATPSPVLPDIVMEAPLNSAVPSAGASVIQPSSSPLEASSVNYESIKHEPENP
              400       410       420       430       440       450

        660       670       680       690       700       710      
pF1KSD PPYEEAMSVSLKKVSGIKEEIKEPENINAALQETEAPYISIACDLIKETKLSAEPAPDFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPYEEAMSVSLKKVSGIKEEIKEPENINAALQETEAPYISIACDLIKETKLSAEPAPDFS
              460       470       480       490       500       510

        720       730       740       750       760       770      
pF1KSD DYSEMAKVEQPVPDHSELVEDSSPDSEPVDLFSDDSIPDVPQKQDETVMLVKESLTETSF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DYSEMAKVEQPVPDHSELVEDSSPDSEPVDLFSDDSIPDVPQKQDETVMLVKESLTETSF
              520       530       540       550       560       570

        780       790       800       810       820       830      
pF1KSD ESMIEYENKEKLSALPPEGGKPYLESFKLSLDNTKDTLLPDEVSTLSKKEKIPLQMEELS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESMIEYENKEKLSALPPEGGKPYLESFKLSLDNTKDTLLPDEVSTLSKKEKIPLQMEELS
              580       590       600       610       620       630

        840       850       860       870       880       890      
pF1KSD TAVYSNDDLFISKEAQIRETETFSDSSPIEIIDEFPTLISSKTDSFSKLAREYTDLEVSH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TAVYSNDDLFISKEAQIRETETFSDSSPIEIIDEFPTLISSKTDSFSKLAREYTDLEVSH
              640       650       660       670       680       690

        900       910       920       930       940       950      
pF1KSD KSEIANAPDGAGSLPCTELPHDLSLKNIQPKVEEKISFSDDFSKNGSATSKVLLLPPDVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSEIANAPDGAGSLPCTELPHDLSLKNIQPKVEEKISFSDDFSKNGSATSKVLLLPPDVS
              700       710       720       730       740       750

        960       970       980       990      1000      1010      
pF1KSD ALATQAEIESIVKPKVLVKEAEKKLPSDTEKEDRSPSAIFSAELSKTSVVDLLYWRDIKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALATQAEIESIVKPKVLVKEAEKKLPSDTEKEDRSPSAIFSAELSKTSVVDLLYWRDIKK
              760       770       780       790       800       810

       1020      1030      1040      1050      1060      1070      
pF1KSD TGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAY
              820       830       840       850       860       870

       1080      1090      1100      1110      1120      1130      
pF1KSD LESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFN
              880       890       900       910       920       930

       1140      1150      1160      1170      1180      1190  
pF1KSD GLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKAE
              940       950       960       970       980      

>>NP_001308789 (OMIM: 604475) reticulon-4 isoform E [Hom  (986 aa)
 initn: 6195 init1: 6195 opt: 6195  Z-score: 2359.0  bits: 448.2 E(85289): 1.2e-124
Smith-Waterman score: 6195; 100.0% identity (100.0% similar) in 986 aa overlap (207-1192:1-986)

        180       190       200       210       220       230      
pF1KSD KRRGSSGSVDETLFALPAASEPVIRSSAENMDLKEQPGNTISAGQEDFPSVLLETAASLP
                                     ::::::::::::::::::::::::::::::
NP_001                               MDLKEQPGNTISAGQEDFPSVLLETAASLP
                                             10        20        30

        240       250       260       270       280       290      
pF1KSD SLSPLSAASFKEHEYLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLSPLSAASFKEHEYLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE
               40        50        60        70        80        90

        300       310       320       330       340       350      
pF1KSD YSEMGSSFSVSPKAESAVIVANPREEIIVKNKDEEEKLVSNNILHNQQELPTALTKLVKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YSEMGSSFSVSPKAESAVIVANPREEIIVKNKDEEEKLVSNNILHNQQELPTALTKLVKE
              100       110       120       130       140       150

        360       370       380       390       400       410      
pF1KSD DEVVSSEKAKDSFNEKRVAVEAPMREEYADFKPFERVWEVKDSKEDSDMLAAGGKIESNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DEVVSSEKAKDSFNEKRVAVEAPMREEYADFKPFERVWEVKDSKEDSDMLAAGGKIESNL
              160       170       180       190       200       210

        420       430       440       450       460       470      
pF1KSD ESKVDKKCFADSLEQTNHEKDSESSNDDTSFPSTPEGIKDRSGAYITCAPFNPAATESIA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESKVDKKCFADSLEQTNHEKDSESSNDDTSFPSTPEGIKDRSGAYITCAPFNPAATESIA
              220       230       240       250       260       270

        480       490       500       510       520       530      
pF1KSD TNIFPLLGDPTSENKTDEKKIEEKKAQIVTEKNTSTKTSNPFLVAAQDSETDYVTTDNLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TNIFPLLGDPTSENKTDEKKIEEKKAQIVTEKNTSTKTSNPFLVAAQDSETDYVTTDNLT
              280       290       300       310       320       330

        540       550       560       570       580       590      
pF1KSD KVTEEVVANMPEGLTPDLVQEACESELNEVTGTKIAYETKMDLVQTSEVMQESLYPAAQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVTEEVVANMPEGLTPDLVQEACESELNEVTGTKIAYETKMDLVQTSEVMQESLYPAAQL
              340       350       360       370       380       390

        600       610       620       630       640       650      
pF1KSD CPSFEESEATPSPVLPDIVMEAPLNSAVPSAGASVIQPSSSPLEASSVNYESIKHEPENP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CPSFEESEATPSPVLPDIVMEAPLNSAVPSAGASVIQPSSSPLEASSVNYESIKHEPENP
              400       410       420       430       440       450

        660       670       680       690       700       710      
pF1KSD PPYEEAMSVSLKKVSGIKEEIKEPENINAALQETEAPYISIACDLIKETKLSAEPAPDFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPYEEAMSVSLKKVSGIKEEIKEPENINAALQETEAPYISIACDLIKETKLSAEPAPDFS
              460       470       480       490       500       510

        720       730       740       750       760       770      
pF1KSD DYSEMAKVEQPVPDHSELVEDSSPDSEPVDLFSDDSIPDVPQKQDETVMLVKESLTETSF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DYSEMAKVEQPVPDHSELVEDSSPDSEPVDLFSDDSIPDVPQKQDETVMLVKESLTETSF
              520       530       540       550       560       570

        780       790       800       810       820       830      
pF1KSD ESMIEYENKEKLSALPPEGGKPYLESFKLSLDNTKDTLLPDEVSTLSKKEKIPLQMEELS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESMIEYENKEKLSALPPEGGKPYLESFKLSLDNTKDTLLPDEVSTLSKKEKIPLQMEELS
              580       590       600       610       620       630

        840       850       860       870       880       890      
pF1KSD TAVYSNDDLFISKEAQIRETETFSDSSPIEIIDEFPTLISSKTDSFSKLAREYTDLEVSH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TAVYSNDDLFISKEAQIRETETFSDSSPIEIIDEFPTLISSKTDSFSKLAREYTDLEVSH
              640       650       660       670       680       690

        900       910       920       930       940       950      
pF1KSD KSEIANAPDGAGSLPCTELPHDLSLKNIQPKVEEKISFSDDFSKNGSATSKVLLLPPDVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSEIANAPDGAGSLPCTELPHDLSLKNIQPKVEEKISFSDDFSKNGSATSKVLLLPPDVS
              700       710       720       730       740       750

        960       970       980       990      1000      1010      
pF1KSD ALATQAEIESIVKPKVLVKEAEKKLPSDTEKEDRSPSAIFSAELSKTSVVDLLYWRDIKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALATQAEIESIVKPKVLVKEAEKKLPSDTEKEDRSPSAIFSAELSKTSVVDLLYWRDIKK
              760       770       780       790       800       810

       1020      1030      1040      1050      1060      1070      
pF1KSD TGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAY
              820       830       840       850       860       870

       1080      1090      1100      1110      1120      1130      
pF1KSD LESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFN
              880       890       900       910       920       930

       1140      1150      1160      1170      1180      1190  
pF1KSD GLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKAE
              940       950       960       970       980      

>>NP_001308792 (OMIM: 604475) reticulon-4 isoform E [Hom  (986 aa)
 initn: 6195 init1: 6195 opt: 6195  Z-score: 2359.0  bits: 448.2 E(85289): 1.2e-124
Smith-Waterman score: 6195; 100.0% identity (100.0% similar) in 986 aa overlap (207-1192:1-986)

        180       190       200       210       220       230      
pF1KSD KRRGSSGSVDETLFALPAASEPVIRSSAENMDLKEQPGNTISAGQEDFPSVLLETAASLP
                                     ::::::::::::::::::::::::::::::
NP_001                               MDLKEQPGNTISAGQEDFPSVLLETAASLP
                                             10        20        30

        240       250       260       270       280       290      
pF1KSD SLSPLSAASFKEHEYLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLSPLSAASFKEHEYLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE
               40        50        60        70        80        90

        300       310       320       330       340       350      
pF1KSD YSEMGSSFSVSPKAESAVIVANPREEIIVKNKDEEEKLVSNNILHNQQELPTALTKLVKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YSEMGSSFSVSPKAESAVIVANPREEIIVKNKDEEEKLVSNNILHNQQELPTALTKLVKE
              100       110       120       130       140       150

        360       370       380       390       400       410      
pF1KSD DEVVSSEKAKDSFNEKRVAVEAPMREEYADFKPFERVWEVKDSKEDSDMLAAGGKIESNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DEVVSSEKAKDSFNEKRVAVEAPMREEYADFKPFERVWEVKDSKEDSDMLAAGGKIESNL
              160       170       180       190       200       210

        420       430       440       450       460       470      
pF1KSD ESKVDKKCFADSLEQTNHEKDSESSNDDTSFPSTPEGIKDRSGAYITCAPFNPAATESIA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESKVDKKCFADSLEQTNHEKDSESSNDDTSFPSTPEGIKDRSGAYITCAPFNPAATESIA
              220       230       240       250       260       270

        480       490       500       510       520       530      
pF1KSD TNIFPLLGDPTSENKTDEKKIEEKKAQIVTEKNTSTKTSNPFLVAAQDSETDYVTTDNLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TNIFPLLGDPTSENKTDEKKIEEKKAQIVTEKNTSTKTSNPFLVAAQDSETDYVTTDNLT
              280       290       300       310       320       330

        540       550       560       570       580       590      
pF1KSD KVTEEVVANMPEGLTPDLVQEACESELNEVTGTKIAYETKMDLVQTSEVMQESLYPAAQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVTEEVVANMPEGLTPDLVQEACESELNEVTGTKIAYETKMDLVQTSEVMQESLYPAAQL
              340       350       360       370       380       390

        600       610       620       630       640       650      
pF1KSD CPSFEESEATPSPVLPDIVMEAPLNSAVPSAGASVIQPSSSPLEASSVNYESIKHEPENP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CPSFEESEATPSPVLPDIVMEAPLNSAVPSAGASVIQPSSSPLEASSVNYESIKHEPENP
              400       410       420       430       440       450

        660       670       680       690       700       710      
pF1KSD PPYEEAMSVSLKKVSGIKEEIKEPENINAALQETEAPYISIACDLIKETKLSAEPAPDFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPYEEAMSVSLKKVSGIKEEIKEPENINAALQETEAPYISIACDLIKETKLSAEPAPDFS
              460       470       480       490       500       510

        720       730       740       750       760       770      
pF1KSD DYSEMAKVEQPVPDHSELVEDSSPDSEPVDLFSDDSIPDVPQKQDETVMLVKESLTETSF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DYSEMAKVEQPVPDHSELVEDSSPDSEPVDLFSDDSIPDVPQKQDETVMLVKESLTETSF
              520       530       540       550       560       570

        780       790       800       810       820       830      
pF1KSD ESMIEYENKEKLSALPPEGGKPYLESFKLSLDNTKDTLLPDEVSTLSKKEKIPLQMEELS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESMIEYENKEKLSALPPEGGKPYLESFKLSLDNTKDTLLPDEVSTLSKKEKIPLQMEELS
              580       590       600       610       620       630

        840       850       860       870       880       890      
pF1KSD TAVYSNDDLFISKEAQIRETETFSDSSPIEIIDEFPTLISSKTDSFSKLAREYTDLEVSH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TAVYSNDDLFISKEAQIRETETFSDSSPIEIIDEFPTLISSKTDSFSKLAREYTDLEVSH
              640       650       660       670       680       690

        900       910       920       930       940       950      
pF1KSD KSEIANAPDGAGSLPCTELPHDLSLKNIQPKVEEKISFSDDFSKNGSATSKVLLLPPDVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSEIANAPDGAGSLPCTELPHDLSLKNIQPKVEEKISFSDDFSKNGSATSKVLLLPPDVS
              700       710       720       730       740       750

        960       970       980       990      1000      1010      
pF1KSD ALATQAEIESIVKPKVLVKEAEKKLPSDTEKEDRSPSAIFSAELSKTSVVDLLYWRDIKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALATQAEIESIVKPKVLVKEAEKKLPSDTEKEDRSPSAIFSAELSKTSVVDLLYWRDIKK
              760       770       780       790       800       810

       1020      1030      1040      1050      1060      1070      
pF1KSD TGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAY
              820       830       840       850       860       870

       1080      1090      1100      1110      1120      1130      
pF1KSD LESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFN
              880       890       900       910       920       930

       1140      1150      1160      1170      1180      1190  
pF1KSD GLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKAE
              940       950       960       970       980      




1192 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 03:58:05 2016 done: Thu Nov  3 03:58:07 2016
 Total Scan time: 14.280 Total Display time:  0.380

Function used was FASTA [36.3.4 Apr, 2011]
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