Result of FASTA (omim) for pF1KSDA0645
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KSDA0645, 1572 aa
  1>>>pF1KSDA0645 1572 - 1572 aa - 1572 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.0790+/-0.00043; mu= 14.9619+/- 0.027
 mean_var=94.9001+/-18.701, 0's: 0 Z-trim(112.8): 51  B-trim: 1150 in 1/49
 Lambda= 0.131656
 statistics sampled from 21867 (21905) to 21867 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.601), E-opt: 0.2 (0.257), width:  16
 Scan time: 14.490

The best scores are:                                      opt bits E(85289)
XP_011528861 (OMIM: 604364,614191) PREDICTED: DEP  (1572) 10626 2029.6       0
XP_016884600 (OMIM: 604364,614191) PREDICTED: DEP  (1572) 10626 2029.6       0
NP_055477 (OMIM: 604364,614191) DEP domain-contain (1572) 10626 2029.6       0
XP_011528859 (OMIM: 604364,614191) PREDICTED: DEP  (1594) 7302 1398.2       0
NP_001129501 (OMIM: 604364,614191) DEP domain-cont (1594) 7302 1398.2       0
XP_016884598 (OMIM: 604364,614191) PREDICTED: DEP  (1594) 7302 1398.2       0
NP_001229826 (OMIM: 604364,614191) DEP domain-cont (1503) 5790 1111.0       0
XP_011528865 (OMIM: 604364,614191) PREDICTED: DEP  (1503) 5790 1111.0       0
XP_016884599 (OMIM: 604364,614191) PREDICTED: DEP  (1581) 5790 1111.0       0
XP_011528860 (OMIM: 604364,614191) PREDICTED: DEP  (1581) 5790 1111.0       0
XP_016884602 (OMIM: 604364,614191) PREDICTED: DEP  ( 727) 4847 931.9       0
XP_011528870 (OMIM: 604364,614191) PREDICTED: DEP  (1176) 4844 931.3       0
XP_011528867 (OMIM: 604364,614191) PREDICTED: DEP  (1307) 4844 931.3       0
XP_011528864 (OMIM: 604364,614191) PREDICTED: DEP  (1515) 4844 931.4       0
NP_001229825 (OMIM: 604364,614191) DEP domain-cont (1603) 4844 931.4       0
XP_005261919 (OMIM: 604364,614191) PREDICTED: DEP  (1603) 4844 931.4       0
XP_016884603 (OMIM: 604364,614191) PREDICTED: DEP  ( 716) 4690 902.0       0
XP_016884604 (OMIM: 604364,614191) PREDICTED: DEP  ( 649) 4186 806.3       0
XP_011528863 (OMIM: 604364,614191) PREDICTED: DEP  (1516) 4184 806.0       0
XP_011528862 (OMIM: 604364,614191) PREDICTED: DEP  (1525) 4184 806.0       0
XP_016884601 (OMIM: 604364,614191) PREDICTED: DEP  (1525) 4184 806.0       0
NP_001007189 (OMIM: 604364,614191) DEP domain-cont ( 559) 3697 713.4 1.3e-204
XP_011528871 (OMIM: 604364,614191) PREDICTED: DEP  ( 901) 3333 644.3 1.3e-183


>>XP_011528861 (OMIM: 604364,614191) PREDICTED: DEP doma  (1572 aa)
 initn: 10626 init1: 10626 opt: 10626  Z-score: 10899.5  bits: 2029.6 E(85289):    0
Smith-Waterman score: 10626; 100.0% identity (100.0% similar) in 1572 aa overlap (1-1572:1-1572)

               10        20        30        40        50        60
pF1KSD MRTTKVYKLVIHKKGFGGSDDELVVNPKVFPHIKLGDIVEIAHPNDEYSPLLLQVKSLKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRTTKVYKLVIHKKGFGGSDDELVVNPKVFPHIKLGDIVEIAHPNDEYSPLLLQVKSLKE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD DLQKETISVDQTVTQVFRLRPYQDVYVNVVDPKDVTLDLVELTFKDQYIGRGDMWRLKKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLQKETISVDQTVTQVFRLRPYQDVYVNVVDPKDVTLDLVELTFKDQYIGRGDMWRLKKS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD LVSTCAYITQKVEFAGIRAQAGELWVKNEKVMCGYISEDTRVVFRSTSAMVYIFIQMSCE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVSTCAYITQKVEFAGIRAQAGELWVKNEKVMCGYISEDTRVVFRSTSAMVYIFIQMSCE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD MWDFDIYGDLYFEKAVNGFLADLFTKWKEKNCSHEVTVVLFSRTFYDAKSVDEFPEINRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MWDFDIYGDLYFEKAVNGFLADLFTKWKEKNCSHEVTVVLFSRTFYDAKSVDEFPEINRA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD SIRQDHKGRFYEDFYKVVVQNERREEWTSLLVTIKKLFIQYPVLVRLEQAEGFPQGDNST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SIRQDHKGRFYEDFYKVVVQNERREEWTSLLVTIKKLFIQYPVLVRLEQAEGFPQGDNST
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD SAQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFEVDRLLMILTKQRMIDN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SAQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFEVDRLLMILTKQRMIDN
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD GIGVDLVCMGEQPLHAVPLFKLHNRSAPRDSRLGDDYNIPHWINHSFYTSKSQLFCNSFT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GIGVDLVCMGEQPLHAVPLFKLHNRSAPRDSRLGDDYNIPHWINHSFYTSKSQLFCNSFT
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD PRIKLAGKKPASEKAKNGRDTSLGSPKESENALPIQVDYDAYDAQVFRLPGPSRAQCLTT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PRIKLAGKKPASEKAKNGRDTSLGSPKESENALPIQVDYDAYDAQVFRLPGPSRAQCLTT
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD CRSVRERESHSRKSASSCDVSSSPSLPSRTLPTEEVRSQASDDSSLGKSANILMIPHPHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CRSVRERESHSRKSASSCDVSSSPSLPSRTLPTEEVRSQASDDSSLGKSANILMIPHPHL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD HQYEVSSSLGYTSTRDVLENMMEPPQRDSSAPGRFHVGSAESMLHVRPGGYTPQRALINP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HQYEVSSSLGYTSTRDVLENMMEPPQRDSSAPGRFHVGSAESMLHVRPGGYTPQRALINP
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD FAPSRMPMKLTSNRRRWMHTFPVGPSGEAIQIHHQTRQNMAELQGSGQRDPTHSSAELLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FAPSRMPMKLTSNRRRWMHTFPVGPSGEAIQIHHQTRQNMAELQGSGQRDPTHSSAELLE
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD LAYHEAAGRHSNSRQPGDGMSFLNFSGTEELSVGLLSNSGAGMNPRTQNKDSLEDSVSTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAYHEAAGRHSNSRQPGDGMSFLNFSGTEELSVGLLSNSGAGMNPRTQNKDSLEDSVSTS
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD PDPMPGFCCTVGVDWKSLTTPACLPLTTDYFPDRQGLQNDYTEGCYDLLPEADIDRRDED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDPMPGFCCTVGVDWKSLTTPACLPLTTDYFPDRQGLQNDYTEGCYDLLPEADIDRRDED
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KSD GVQMTAQQVFEEFICQRLMQGYQIIVQPKTQKPNPAVPPPLSSSPLYSRGLVSRNRPEEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GVQMTAQQVFEEFICQRLMQGYQIIVQPKTQKPNPAVPPPLSSSPLYSRGLVSRNRPEEE
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KSD DQYWLSMGRTFHKVTLKDKMITVTRYLPKYPYESAQIHYTYSLCPSHSDSEFVSCWVEFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DQYWLSMGRTFHKVTLKDKMITVTRYLPKYPYESAQIHYTYSLCPSHSDSEFVSCWVEFS
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KSD HERLEEYKWNYLDQYICSAGSEDFSLIESLKFWRTRFLLLPACVTATKRITEGEAHCDIY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HERLEEYKWNYLDQYICSAGSEDFSLIESLKFWRTRFLLLPACVTATKRITEGEAHCDIY
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KSD GDRPRADEDEWQLLDGFVRFVEGLNRIRRRHRSDRMMRKGTAMKGLQMTGPISTHSLEST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GDRPRADEDEWQLLDGFVRFVEGLNRIRRRHRSDRMMRKGTAMKGLQMTGPISTHSLEST
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KSD APPVGKKGTSALSALLEMEASQKCLGEQQAAVHGGKSSAQSAESSSVAMTPTYMDSPRKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 APPVGKKGTSALSALLEMEASQKCLGEQQAAVHGGKSSAQSAESSSVAMTPTYMDSPRKV
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KSD SVDQTATPMLDGTSLGICTGQSMDRGNSQTFGNSQNIGEQGYSSTNSSDSSSQQLVASSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVDQTATPMLDGTSLGICTGQSMDRGNSQTFGNSQNIGEQGYSSTNSSDSSSQQLVASSL
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KSD TSSSTLTEILEAMKHPSTGVQLLSEQKGLSPYCFISAEVVHWLVNHVEGIQTQAMAIDIM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSSSTLTEILEAMKHPSTGVQLLSEQKGLSPYCFISAEVVHWLVNHVEGIQTQAMAIDIM
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KSD QKMLEEQLITHASGEAWRTFIYGFYFYKIVTDKEPDRVAMQQPATTWHTAGVDDFASFQR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QKMLEEQLITHASGEAWRTFIYGFYFYKIVTDKEPDRVAMQQPATTWHTAGVDDFASFQR
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KSD KWFEVAFVAEELVHSEIPAFLLPWLPSRPASYASRHSSFSRSFGGRSQAAALLAATVPEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KWFEVAFVAEELVHSEIPAFLLPWLPSRPASYASRHSSFSRSFGGRSQAAALLAATVPEQ
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KSD RTVTLDVDVNNRTDRLEWCSCYYHGNFSLNAAFEIKLHWMAVTAAVLFEMVQGWHRKATS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RTVTLDVDVNNRTDRLEWCSCYYHGNFSLNAAFEIKLHWMAVTAAVLFEMVQGWHRKATS
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KSD CGFLLVPVLEGPFALPSYLYGDPLRAQLFIPLNISCLLKEGSEHLFDSFEPETYWDRMHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CGFLLVPVLEGPFALPSYLYGDPLRAQLFIPLNISCLLKEGSEHLFDSFEPETYWDRMHL
             1390      1400      1410      1420      1430      1440

             1450      1460      1470      1480      1490      1500
pF1KSD FQEAIAHRFGFVQDKYSASAFNFPAENKPQYIHVTGTVFLQLPYSKRKFSGQQRRRRNST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FQEAIAHRFGFVQDKYSASAFNFPAENKPQYIHVTGTVFLQLPYSKRKFSGQQRRRRNST
             1450      1460      1470      1480      1490      1500

             1510      1520      1530      1540      1550      1560
pF1KSD SSTNQNMFCEERVGYNWAYNTMLTKTWRSSATGDEKFADRLLKDFTDFCINRDNRLVTFW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSTNQNMFCEERVGYNWAYNTMLTKTWRSSATGDEKFADRLLKDFTDFCINRDNRLVTFW
             1510      1520      1530      1540      1550      1560

             1570  
pF1KSD TSCLEKMHASAP
       ::::::::::::
XP_011 TSCLEKMHASAP
             1570  

>>XP_016884600 (OMIM: 604364,614191) PREDICTED: DEP doma  (1572 aa)
 initn: 10626 init1: 10626 opt: 10626  Z-score: 10899.5  bits: 2029.6 E(85289):    0
Smith-Waterman score: 10626; 100.0% identity (100.0% similar) in 1572 aa overlap (1-1572:1-1572)

               10        20        30        40        50        60
pF1KSD MRTTKVYKLVIHKKGFGGSDDELVVNPKVFPHIKLGDIVEIAHPNDEYSPLLLQVKSLKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MRTTKVYKLVIHKKGFGGSDDELVVNPKVFPHIKLGDIVEIAHPNDEYSPLLLQVKSLKE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD DLQKETISVDQTVTQVFRLRPYQDVYVNVVDPKDVTLDLVELTFKDQYIGRGDMWRLKKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLQKETISVDQTVTQVFRLRPYQDVYVNVVDPKDVTLDLVELTFKDQYIGRGDMWRLKKS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD LVSTCAYITQKVEFAGIRAQAGELWVKNEKVMCGYISEDTRVVFRSTSAMVYIFIQMSCE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVSTCAYITQKVEFAGIRAQAGELWVKNEKVMCGYISEDTRVVFRSTSAMVYIFIQMSCE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD MWDFDIYGDLYFEKAVNGFLADLFTKWKEKNCSHEVTVVLFSRTFYDAKSVDEFPEINRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MWDFDIYGDLYFEKAVNGFLADLFTKWKEKNCSHEVTVVLFSRTFYDAKSVDEFPEINRA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD SIRQDHKGRFYEDFYKVVVQNERREEWTSLLVTIKKLFIQYPVLVRLEQAEGFPQGDNST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SIRQDHKGRFYEDFYKVVVQNERREEWTSLLVTIKKLFIQYPVLVRLEQAEGFPQGDNST
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD SAQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFEVDRLLMILTKQRMIDN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SAQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFEVDRLLMILTKQRMIDN
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD GIGVDLVCMGEQPLHAVPLFKLHNRSAPRDSRLGDDYNIPHWINHSFYTSKSQLFCNSFT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GIGVDLVCMGEQPLHAVPLFKLHNRSAPRDSRLGDDYNIPHWINHSFYTSKSQLFCNSFT
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD PRIKLAGKKPASEKAKNGRDTSLGSPKESENALPIQVDYDAYDAQVFRLPGPSRAQCLTT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRIKLAGKKPASEKAKNGRDTSLGSPKESENALPIQVDYDAYDAQVFRLPGPSRAQCLTT
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD CRSVRERESHSRKSASSCDVSSSPSLPSRTLPTEEVRSQASDDSSLGKSANILMIPHPHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CRSVRERESHSRKSASSCDVSSSPSLPSRTLPTEEVRSQASDDSSLGKSANILMIPHPHL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD HQYEVSSSLGYTSTRDVLENMMEPPQRDSSAPGRFHVGSAESMLHVRPGGYTPQRALINP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HQYEVSSSLGYTSTRDVLENMMEPPQRDSSAPGRFHVGSAESMLHVRPGGYTPQRALINP
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD FAPSRMPMKLTSNRRRWMHTFPVGPSGEAIQIHHQTRQNMAELQGSGQRDPTHSSAELLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FAPSRMPMKLTSNRRRWMHTFPVGPSGEAIQIHHQTRQNMAELQGSGQRDPTHSSAELLE
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD LAYHEAAGRHSNSRQPGDGMSFLNFSGTEELSVGLLSNSGAGMNPRTQNKDSLEDSVSTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAYHEAAGRHSNSRQPGDGMSFLNFSGTEELSVGLLSNSGAGMNPRTQNKDSLEDSVSTS
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD PDPMPGFCCTVGVDWKSLTTPACLPLTTDYFPDRQGLQNDYTEGCYDLLPEADIDRRDED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PDPMPGFCCTVGVDWKSLTTPACLPLTTDYFPDRQGLQNDYTEGCYDLLPEADIDRRDED
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KSD GVQMTAQQVFEEFICQRLMQGYQIIVQPKTQKPNPAVPPPLSSSPLYSRGLVSRNRPEEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GVQMTAQQVFEEFICQRLMQGYQIIVQPKTQKPNPAVPPPLSSSPLYSRGLVSRNRPEEE
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KSD DQYWLSMGRTFHKVTLKDKMITVTRYLPKYPYESAQIHYTYSLCPSHSDSEFVSCWVEFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DQYWLSMGRTFHKVTLKDKMITVTRYLPKYPYESAQIHYTYSLCPSHSDSEFVSCWVEFS
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KSD HERLEEYKWNYLDQYICSAGSEDFSLIESLKFWRTRFLLLPACVTATKRITEGEAHCDIY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HERLEEYKWNYLDQYICSAGSEDFSLIESLKFWRTRFLLLPACVTATKRITEGEAHCDIY
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KSD GDRPRADEDEWQLLDGFVRFVEGLNRIRRRHRSDRMMRKGTAMKGLQMTGPISTHSLEST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDRPRADEDEWQLLDGFVRFVEGLNRIRRRHRSDRMMRKGTAMKGLQMTGPISTHSLEST
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KSD APPVGKKGTSALSALLEMEASQKCLGEQQAAVHGGKSSAQSAESSSVAMTPTYMDSPRKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APPVGKKGTSALSALLEMEASQKCLGEQQAAVHGGKSSAQSAESSSVAMTPTYMDSPRKV
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KSD SVDQTATPMLDGTSLGICTGQSMDRGNSQTFGNSQNIGEQGYSSTNSSDSSSQQLVASSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVDQTATPMLDGTSLGICTGQSMDRGNSQTFGNSQNIGEQGYSSTNSSDSSSQQLVASSL
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KSD TSSSTLTEILEAMKHPSTGVQLLSEQKGLSPYCFISAEVVHWLVNHVEGIQTQAMAIDIM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSSSTLTEILEAMKHPSTGVQLLSEQKGLSPYCFISAEVVHWLVNHVEGIQTQAMAIDIM
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KSD QKMLEEQLITHASGEAWRTFIYGFYFYKIVTDKEPDRVAMQQPATTWHTAGVDDFASFQR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QKMLEEQLITHASGEAWRTFIYGFYFYKIVTDKEPDRVAMQQPATTWHTAGVDDFASFQR
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KSD KWFEVAFVAEELVHSEIPAFLLPWLPSRPASYASRHSSFSRSFGGRSQAAALLAATVPEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KWFEVAFVAEELVHSEIPAFLLPWLPSRPASYASRHSSFSRSFGGRSQAAALLAATVPEQ
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KSD RTVTLDVDVNNRTDRLEWCSCYYHGNFSLNAAFEIKLHWMAVTAAVLFEMVQGWHRKATS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTVTLDVDVNNRTDRLEWCSCYYHGNFSLNAAFEIKLHWMAVTAAVLFEMVQGWHRKATS
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KSD CGFLLVPVLEGPFALPSYLYGDPLRAQLFIPLNISCLLKEGSEHLFDSFEPETYWDRMHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CGFLLVPVLEGPFALPSYLYGDPLRAQLFIPLNISCLLKEGSEHLFDSFEPETYWDRMHL
             1390      1400      1410      1420      1430      1440

             1450      1460      1470      1480      1490      1500
pF1KSD FQEAIAHRFGFVQDKYSASAFNFPAENKPQYIHVTGTVFLQLPYSKRKFSGQQRRRRNST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FQEAIAHRFGFVQDKYSASAFNFPAENKPQYIHVTGTVFLQLPYSKRKFSGQQRRRRNST
             1450      1460      1470      1480      1490      1500

             1510      1520      1530      1540      1550      1560
pF1KSD SSTNQNMFCEERVGYNWAYNTMLTKTWRSSATGDEKFADRLLKDFTDFCINRDNRLVTFW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSTNQNMFCEERVGYNWAYNTMLTKTWRSSATGDEKFADRLLKDFTDFCINRDNRLVTFW
             1510      1520      1530      1540      1550      1560

             1570  
pF1KSD TSCLEKMHASAP
       ::::::::::::
XP_016 TSCLEKMHASAP
             1570  

>>NP_055477 (OMIM: 604364,614191) DEP domain-containing   (1572 aa)
 initn: 10626 init1: 10626 opt: 10626  Z-score: 10899.5  bits: 2029.6 E(85289):    0
Smith-Waterman score: 10626; 100.0% identity (100.0% similar) in 1572 aa overlap (1-1572:1-1572)

               10        20        30        40        50        60
pF1KSD MRTTKVYKLVIHKKGFGGSDDELVVNPKVFPHIKLGDIVEIAHPNDEYSPLLLQVKSLKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MRTTKVYKLVIHKKGFGGSDDELVVNPKVFPHIKLGDIVEIAHPNDEYSPLLLQVKSLKE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD DLQKETISVDQTVTQVFRLRPYQDVYVNVVDPKDVTLDLVELTFKDQYIGRGDMWRLKKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DLQKETISVDQTVTQVFRLRPYQDVYVNVVDPKDVTLDLVELTFKDQYIGRGDMWRLKKS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD LVSTCAYITQKVEFAGIRAQAGELWVKNEKVMCGYISEDTRVVFRSTSAMVYIFIQMSCE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LVSTCAYITQKVEFAGIRAQAGELWVKNEKVMCGYISEDTRVVFRSTSAMVYIFIQMSCE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD MWDFDIYGDLYFEKAVNGFLADLFTKWKEKNCSHEVTVVLFSRTFYDAKSVDEFPEINRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MWDFDIYGDLYFEKAVNGFLADLFTKWKEKNCSHEVTVVLFSRTFYDAKSVDEFPEINRA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD SIRQDHKGRFYEDFYKVVVQNERREEWTSLLVTIKKLFIQYPVLVRLEQAEGFPQGDNST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SIRQDHKGRFYEDFYKVVVQNERREEWTSLLVTIKKLFIQYPVLVRLEQAEGFPQGDNST
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD SAQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFEVDRLLMILTKQRMIDN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SAQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFEVDRLLMILTKQRMIDN
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD GIGVDLVCMGEQPLHAVPLFKLHNRSAPRDSRLGDDYNIPHWINHSFYTSKSQLFCNSFT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GIGVDLVCMGEQPLHAVPLFKLHNRSAPRDSRLGDDYNIPHWINHSFYTSKSQLFCNSFT
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD PRIKLAGKKPASEKAKNGRDTSLGSPKESENALPIQVDYDAYDAQVFRLPGPSRAQCLTT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PRIKLAGKKPASEKAKNGRDTSLGSPKESENALPIQVDYDAYDAQVFRLPGPSRAQCLTT
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD CRSVRERESHSRKSASSCDVSSSPSLPSRTLPTEEVRSQASDDSSLGKSANILMIPHPHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 CRSVRERESHSRKSASSCDVSSSPSLPSRTLPTEEVRSQASDDSSLGKSANILMIPHPHL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD HQYEVSSSLGYTSTRDVLENMMEPPQRDSSAPGRFHVGSAESMLHVRPGGYTPQRALINP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 HQYEVSSSLGYTSTRDVLENMMEPPQRDSSAPGRFHVGSAESMLHVRPGGYTPQRALINP
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD FAPSRMPMKLTSNRRRWMHTFPVGPSGEAIQIHHQTRQNMAELQGSGQRDPTHSSAELLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 FAPSRMPMKLTSNRRRWMHTFPVGPSGEAIQIHHQTRQNMAELQGSGQRDPTHSSAELLE
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD LAYHEAAGRHSNSRQPGDGMSFLNFSGTEELSVGLLSNSGAGMNPRTQNKDSLEDSVSTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LAYHEAAGRHSNSRQPGDGMSFLNFSGTEELSVGLLSNSGAGMNPRTQNKDSLEDSVSTS
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD PDPMPGFCCTVGVDWKSLTTPACLPLTTDYFPDRQGLQNDYTEGCYDLLPEADIDRRDED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PDPMPGFCCTVGVDWKSLTTPACLPLTTDYFPDRQGLQNDYTEGCYDLLPEADIDRRDED
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KSD GVQMTAQQVFEEFICQRLMQGYQIIVQPKTQKPNPAVPPPLSSSPLYSRGLVSRNRPEEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GVQMTAQQVFEEFICQRLMQGYQIIVQPKTQKPNPAVPPPLSSSPLYSRGLVSRNRPEEE
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KSD DQYWLSMGRTFHKVTLKDKMITVTRYLPKYPYESAQIHYTYSLCPSHSDSEFVSCWVEFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DQYWLSMGRTFHKVTLKDKMITVTRYLPKYPYESAQIHYTYSLCPSHSDSEFVSCWVEFS
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KSD HERLEEYKWNYLDQYICSAGSEDFSLIESLKFWRTRFLLLPACVTATKRITEGEAHCDIY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 HERLEEYKWNYLDQYICSAGSEDFSLIESLKFWRTRFLLLPACVTATKRITEGEAHCDIY
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KSD GDRPRADEDEWQLLDGFVRFVEGLNRIRRRHRSDRMMRKGTAMKGLQMTGPISTHSLEST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GDRPRADEDEWQLLDGFVRFVEGLNRIRRRHRSDRMMRKGTAMKGLQMTGPISTHSLEST
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KSD APPVGKKGTSALSALLEMEASQKCLGEQQAAVHGGKSSAQSAESSSVAMTPTYMDSPRKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 APPVGKKGTSALSALLEMEASQKCLGEQQAAVHGGKSSAQSAESSSVAMTPTYMDSPRKV
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KSD SVDQTATPMLDGTSLGICTGQSMDRGNSQTFGNSQNIGEQGYSSTNSSDSSSQQLVASSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SVDQTATPMLDGTSLGICTGQSMDRGNSQTFGNSQNIGEQGYSSTNSSDSSSQQLVASSL
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KSD TSSSTLTEILEAMKHPSTGVQLLSEQKGLSPYCFISAEVVHWLVNHVEGIQTQAMAIDIM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TSSSTLTEILEAMKHPSTGVQLLSEQKGLSPYCFISAEVVHWLVNHVEGIQTQAMAIDIM
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KSD QKMLEEQLITHASGEAWRTFIYGFYFYKIVTDKEPDRVAMQQPATTWHTAGVDDFASFQR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QKMLEEQLITHASGEAWRTFIYGFYFYKIVTDKEPDRVAMQQPATTWHTAGVDDFASFQR
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KSD KWFEVAFVAEELVHSEIPAFLLPWLPSRPASYASRHSSFSRSFGGRSQAAALLAATVPEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KWFEVAFVAEELVHSEIPAFLLPWLPSRPASYASRHSSFSRSFGGRSQAAALLAATVPEQ
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KSD RTVTLDVDVNNRTDRLEWCSCYYHGNFSLNAAFEIKLHWMAVTAAVLFEMVQGWHRKATS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RTVTLDVDVNNRTDRLEWCSCYYHGNFSLNAAFEIKLHWMAVTAAVLFEMVQGWHRKATS
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KSD CGFLLVPVLEGPFALPSYLYGDPLRAQLFIPLNISCLLKEGSEHLFDSFEPETYWDRMHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 CGFLLVPVLEGPFALPSYLYGDPLRAQLFIPLNISCLLKEGSEHLFDSFEPETYWDRMHL
             1390      1400      1410      1420      1430      1440

             1450      1460      1470      1480      1490      1500
pF1KSD FQEAIAHRFGFVQDKYSASAFNFPAENKPQYIHVTGTVFLQLPYSKRKFSGQQRRRRNST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 FQEAIAHRFGFVQDKYSASAFNFPAENKPQYIHVTGTVFLQLPYSKRKFSGQQRRRRNST
             1450      1460      1470      1480      1490      1500

             1510      1520      1530      1540      1550      1560
pF1KSD SSTNQNMFCEERVGYNWAYNTMLTKTWRSSATGDEKFADRLLKDFTDFCINRDNRLVTFW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SSTNQNMFCEERVGYNWAYNTMLTKTWRSSATGDEKFADRLLKDFTDFCINRDNRLVTFW
             1510      1520      1530      1540      1550      1560

             1570  
pF1KSD TSCLEKMHASAP
       ::::::::::::
NP_055 TSCLEKMHASAP
             1570  

>>XP_011528859 (OMIM: 604364,614191) PREDICTED: DEP doma  (1594 aa)
 initn: 7295 init1: 7295 opt: 7302  Z-score: 7487.3  bits: 1398.2 E(85289):    0
Smith-Waterman score: 10572; 98.6% identity (98.6% similar) in 1594 aa overlap (1-1572:1-1594)

               10        20        30        40        50        60
pF1KSD MRTTKVYKLVIHKKGFGGSDDELVVNPKVFPHIKLGDIVEIAHPNDEYSPLLLQVKSLKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRTTKVYKLVIHKKGFGGSDDELVVNPKVFPHIKLGDIVEIAHPNDEYSPLLLQVKSLKE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD DLQKETISVDQTVTQVFRLRPYQDVYVNVVDPKDVTLDLVELTFKDQYIGRGDMWRLKKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLQKETISVDQTVTQVFRLRPYQDVYVNVVDPKDVTLDLVELTFKDQYIGRGDMWRLKKS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD LVSTCAYITQKVEFAGIRAQAGELWVKNEKVMCGYISEDTRVVFRSTSAMVYIFIQMSCE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVSTCAYITQKVEFAGIRAQAGELWVKNEKVMCGYISEDTRVVFRSTSAMVYIFIQMSCE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD MWDFDIYGDLYFEKAVNGFLADLFTKWKEKNCSHEVTVVLFSRTFYDAKSVDEFPEINRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MWDFDIYGDLYFEKAVNGFLADLFTKWKEKNCSHEVTVVLFSRTFYDAKSVDEFPEINRA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD SIRQDHKGRFYEDFYKVVVQNERREEWTSLLVTIKKLFIQYPVLVRLEQAEGFPQGDNST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SIRQDHKGRFYEDFYKVVVQNERREEWTSLLVTIKKLFIQYPVLVRLEQAEGFPQGDNST
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD SAQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFEVDRLLMILTKQRMIDN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SAQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFEVDRLLMILTKQRMIDN
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD GIGVDLVCMGEQPLHAVPLFKLHNRSAPRDSRLGDDYNIPHWINHSFYTSKSQLFCNSFT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GIGVDLVCMGEQPLHAVPLFKLHNRSAPRDSRLGDDYNIPHWINHSFYTSKSQLFCNSFT
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD PRIKLAGKKPASEKAKNGRDTSLGSPKESENALPIQVDYDAYDAQVFRLPGPSRAQCLTT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PRIKLAGKKPASEKAKNGRDTSLGSPKESENALPIQVDYDAYDAQVFRLPGPSRAQCLTT
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD CRSVRERESHSRKSASSCDVSSSPSLPSRTLPTEEVRSQASDDSSLGKSANILMIPHPHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CRSVRERESHSRKSASSCDVSSSPSLPSRTLPTEEVRSQASDDSSLGKSANILMIPHPHL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD HQYEVSSSLGYTSTRDVLENMMEPPQRDSSAPGRFHVGSAESMLHVRPGGYTPQRALINP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HQYEVSSSLGYTSTRDVLENMMEPPQRDSSAPGRFHVGSAESMLHVRPGGYTPQRALINP
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD FAPSRMPMKLTSNRRRWMHTFPVGPSGEAIQIHHQTRQNMAELQGSGQRDPTHSSAELLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FAPSRMPMKLTSNRRRWMHTFPVGPSGEAIQIHHQTRQNMAELQGSGQRDPTHSSAELLE
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD LAYHEAAGRHSNSRQPGDGMSFLNFSGTEELSVGLLSNSGAGMNPRTQNKDSLEDSVSTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAYHEAAGRHSNSRQPGDGMSFLNFSGTEELSVGLLSNSGAGMNPRTQNKDSLEDSVSTS
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD PDPMPGFCCTVGVDWKSLTTPACLPLTTDYFPDRQGLQNDYTEGCYDLLPEADIDRRDED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDPMPGFCCTVGVDWKSLTTPACLPLTTDYFPDRQGLQNDYTEGCYDLLPEADIDRRDED
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KSD GVQMTAQQVFEEFICQRLMQGYQIIVQPKTQKPNPAVPPPLSSSPLYSRGLVSRNRPEEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GVQMTAQQVFEEFICQRLMQGYQIIVQPKTQKPNPAVPPPLSSSPLYSRGLVSRNRPEEE
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KSD DQYWLSMGRTFHKVTLKDKMITVTRYLPKYPYESAQIHYTYSLCPSHSDSEFVSCWVEFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DQYWLSMGRTFHKVTLKDKMITVTRYLPKYPYESAQIHYTYSLCPSHSDSEFVSCWVEFS
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KSD HERLEEYKWNYLDQYICSAGSEDFSLIESLKFWRTRFLLLPACVTATKRITEGEAHCDIY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HERLEEYKWNYLDQYICSAGSEDFSLIESLKFWRTRFLLLPACVTATKRITEGEAHCDIY
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KSD GDRPRADEDEWQLLDGFVRFVEGLNRIRRRHRSDRMMRKGTAMKGLQMTGPISTHSLEST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GDRPRADEDEWQLLDGFVRFVEGLNRIRRRHRSDRMMRKGTAMKGLQMTGPISTHSLEST
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070          
pF1KSD APPVGKKGTSALSALLEMEASQKCLGEQQAAVHGGKSSAQSAESSSVAMTPTYMDSPRK-
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: 
XP_011 APPVGKKGTSALSALLEMEASQKCLGEQQAAVHGGKSSAQSAESSSVAMTPTYMDSPRKD
             1030      1040      1050      1060      1070      1080

                         1080      1090      1100      1110        
pF1KSD ---------------------VSVDQTATPMLDGTSLGICTGQSMDRGNSQTFGNSQNIG
                            :::::::::::::::::::::::::::::::::::::::
XP_011 GAFFMEFVRSPRTASSAFYPQVSVDQTATPMLDGTSLGICTGQSMDRGNSQTFGNSQNIG
             1090      1100      1110      1120      1130      1140

     1120      1130      1140      1150      1160      1170        
pF1KSD EQGYSSTNSSDSSSQQLVASSLTSSSTLTEILEAMKHPSTGVQLLSEQKGLSPYCFISAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EQGYSSTNSSDSSSQQLVASSLTSSSTLTEILEAMKHPSTGVQLLSEQKGLSPYCFISAE
             1150      1160      1170      1180      1190      1200

     1180      1190      1200      1210      1220      1230        
pF1KSD VVHWLVNHVEGIQTQAMAIDIMQKMLEEQLITHASGEAWRTFIYGFYFYKIVTDKEPDRV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVHWLVNHVEGIQTQAMAIDIMQKMLEEQLITHASGEAWRTFIYGFYFYKIVTDKEPDRV
             1210      1220      1230      1240      1250      1260

     1240      1250      1260      1270      1280      1290        
pF1KSD AMQQPATTWHTAGVDDFASFQRKWFEVAFVAEELVHSEIPAFLLPWLPSRPASYASRHSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AMQQPATTWHTAGVDDFASFQRKWFEVAFVAEELVHSEIPAFLLPWLPSRPASYASRHSS
             1270      1280      1290      1300      1310      1320

     1300      1310      1320      1330      1340      1350        
pF1KSD FSRSFGGRSQAAALLAATVPEQRTVTLDVDVNNRTDRLEWCSCYYHGNFSLNAAFEIKLH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FSRSFGGRSQAAALLAATVPEQRTVTLDVDVNNRTDRLEWCSCYYHGNFSLNAAFEIKLH
             1330      1340      1350      1360      1370      1380

     1360      1370      1380      1390      1400      1410        
pF1KSD WMAVTAAVLFEMVQGWHRKATSCGFLLVPVLEGPFALPSYLYGDPLRAQLFIPLNISCLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WMAVTAAVLFEMVQGWHRKATSCGFLLVPVLEGPFALPSYLYGDPLRAQLFIPLNISCLL
             1390      1400      1410      1420      1430      1440

     1420      1430      1440      1450      1460      1470        
pF1KSD KEGSEHLFDSFEPETYWDRMHLFQEAIAHRFGFVQDKYSASAFNFPAENKPQYIHVTGTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KEGSEHLFDSFEPETYWDRMHLFQEAIAHRFGFVQDKYSASAFNFPAENKPQYIHVTGTV
             1450      1460      1470      1480      1490      1500

     1480      1490      1500      1510      1520      1530        
pF1KSD FLQLPYSKRKFSGQQRRRRNSTSSTNQNMFCEERVGYNWAYNTMLTKTWRSSATGDEKFA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLQLPYSKRKFSGQQRRRRNSTSSTNQNMFCEERVGYNWAYNTMLTKTWRSSATGDEKFA
             1510      1520      1530      1540      1550      1560

     1540      1550      1560      1570  
pF1KSD DRLLKDFTDFCINRDNRLVTFWTSCLEKMHASAP
       ::::::::::::::::::::::::::::::::::
XP_011 DRLLKDFTDFCINRDNRLVTFWTSCLEKMHASAP
             1570      1580      1590    

>>NP_001129501 (OMIM: 604364,614191) DEP domain-containi  (1594 aa)
 initn: 7295 init1: 7295 opt: 7302  Z-score: 7487.3  bits: 1398.2 E(85289):    0
Smith-Waterman score: 10572; 98.6% identity (98.6% similar) in 1594 aa overlap (1-1572:1-1594)

               10        20        30        40        50        60
pF1KSD MRTTKVYKLVIHKKGFGGSDDELVVNPKVFPHIKLGDIVEIAHPNDEYSPLLLQVKSLKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRTTKVYKLVIHKKGFGGSDDELVVNPKVFPHIKLGDIVEIAHPNDEYSPLLLQVKSLKE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD DLQKETISVDQTVTQVFRLRPYQDVYVNVVDPKDVTLDLVELTFKDQYIGRGDMWRLKKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLQKETISVDQTVTQVFRLRPYQDVYVNVVDPKDVTLDLVELTFKDQYIGRGDMWRLKKS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD LVSTCAYITQKVEFAGIRAQAGELWVKNEKVMCGYISEDTRVVFRSTSAMVYIFIQMSCE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVSTCAYITQKVEFAGIRAQAGELWVKNEKVMCGYISEDTRVVFRSTSAMVYIFIQMSCE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD MWDFDIYGDLYFEKAVNGFLADLFTKWKEKNCSHEVTVVLFSRTFYDAKSVDEFPEINRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MWDFDIYGDLYFEKAVNGFLADLFTKWKEKNCSHEVTVVLFSRTFYDAKSVDEFPEINRA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD SIRQDHKGRFYEDFYKVVVQNERREEWTSLLVTIKKLFIQYPVLVRLEQAEGFPQGDNST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SIRQDHKGRFYEDFYKVVVQNERREEWTSLLVTIKKLFIQYPVLVRLEQAEGFPQGDNST
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD SAQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFEVDRLLMILTKQRMIDN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SAQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFEVDRLLMILTKQRMIDN
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD GIGVDLVCMGEQPLHAVPLFKLHNRSAPRDSRLGDDYNIPHWINHSFYTSKSQLFCNSFT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GIGVDLVCMGEQPLHAVPLFKLHNRSAPRDSRLGDDYNIPHWINHSFYTSKSQLFCNSFT
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD PRIKLAGKKPASEKAKNGRDTSLGSPKESENALPIQVDYDAYDAQVFRLPGPSRAQCLTT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PRIKLAGKKPASEKAKNGRDTSLGSPKESENALPIQVDYDAYDAQVFRLPGPSRAQCLTT
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD CRSVRERESHSRKSASSCDVSSSPSLPSRTLPTEEVRSQASDDSSLGKSANILMIPHPHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CRSVRERESHSRKSASSCDVSSSPSLPSRTLPTEEVRSQASDDSSLGKSANILMIPHPHL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD HQYEVSSSLGYTSTRDVLENMMEPPQRDSSAPGRFHVGSAESMLHVRPGGYTPQRALINP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HQYEVSSSLGYTSTRDVLENMMEPPQRDSSAPGRFHVGSAESMLHVRPGGYTPQRALINP
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD FAPSRMPMKLTSNRRRWMHTFPVGPSGEAIQIHHQTRQNMAELQGSGQRDPTHSSAELLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FAPSRMPMKLTSNRRRWMHTFPVGPSGEAIQIHHQTRQNMAELQGSGQRDPTHSSAELLE
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD LAYHEAAGRHSNSRQPGDGMSFLNFSGTEELSVGLLSNSGAGMNPRTQNKDSLEDSVSTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAYHEAAGRHSNSRQPGDGMSFLNFSGTEELSVGLLSNSGAGMNPRTQNKDSLEDSVSTS
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD PDPMPGFCCTVGVDWKSLTTPACLPLTTDYFPDRQGLQNDYTEGCYDLLPEADIDRRDED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDPMPGFCCTVGVDWKSLTTPACLPLTTDYFPDRQGLQNDYTEGCYDLLPEADIDRRDED
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KSD GVQMTAQQVFEEFICQRLMQGYQIIVQPKTQKPNPAVPPPLSSSPLYSRGLVSRNRPEEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVQMTAQQVFEEFICQRLMQGYQIIVQPKTQKPNPAVPPPLSSSPLYSRGLVSRNRPEEE
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KSD DQYWLSMGRTFHKVTLKDKMITVTRYLPKYPYESAQIHYTYSLCPSHSDSEFVSCWVEFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DQYWLSMGRTFHKVTLKDKMITVTRYLPKYPYESAQIHYTYSLCPSHSDSEFVSCWVEFS
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KSD HERLEEYKWNYLDQYICSAGSEDFSLIESLKFWRTRFLLLPACVTATKRITEGEAHCDIY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HERLEEYKWNYLDQYICSAGSEDFSLIESLKFWRTRFLLLPACVTATKRITEGEAHCDIY
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KSD GDRPRADEDEWQLLDGFVRFVEGLNRIRRRHRSDRMMRKGTAMKGLQMTGPISTHSLEST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GDRPRADEDEWQLLDGFVRFVEGLNRIRRRHRSDRMMRKGTAMKGLQMTGPISTHSLEST
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070          
pF1KSD APPVGKKGTSALSALLEMEASQKCLGEQQAAVHGGKSSAQSAESSSVAMTPTYMDSPRK-
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: 
NP_001 APPVGKKGTSALSALLEMEASQKCLGEQQAAVHGGKSSAQSAESSSVAMTPTYMDSPRKD
             1030      1040      1050      1060      1070      1080

                         1080      1090      1100      1110        
pF1KSD ---------------------VSVDQTATPMLDGTSLGICTGQSMDRGNSQTFGNSQNIG
                            :::::::::::::::::::::::::::::::::::::::
NP_001 GAFFMEFVRSPRTASSAFYPQVSVDQTATPMLDGTSLGICTGQSMDRGNSQTFGNSQNIG
             1090      1100      1110      1120      1130      1140

     1120      1130      1140      1150      1160      1170        
pF1KSD EQGYSSTNSSDSSSQQLVASSLTSSSTLTEILEAMKHPSTGVQLLSEQKGLSPYCFISAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EQGYSSTNSSDSSSQQLVASSLTSSSTLTEILEAMKHPSTGVQLLSEQKGLSPYCFISAE
             1150      1160      1170      1180      1190      1200

     1180      1190      1200      1210      1220      1230        
pF1KSD VVHWLVNHVEGIQTQAMAIDIMQKMLEEQLITHASGEAWRTFIYGFYFYKIVTDKEPDRV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVHWLVNHVEGIQTQAMAIDIMQKMLEEQLITHASGEAWRTFIYGFYFYKIVTDKEPDRV
             1210      1220      1230      1240      1250      1260

     1240      1250      1260      1270      1280      1290        
pF1KSD AMQQPATTWHTAGVDDFASFQRKWFEVAFVAEELVHSEIPAFLLPWLPSRPASYASRHSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AMQQPATTWHTAGVDDFASFQRKWFEVAFVAEELVHSEIPAFLLPWLPSRPASYASRHSS
             1270      1280      1290      1300      1310      1320

     1300      1310      1320      1330      1340      1350        
pF1KSD FSRSFGGRSQAAALLAATVPEQRTVTLDVDVNNRTDRLEWCSCYYHGNFSLNAAFEIKLH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FSRSFGGRSQAAALLAATVPEQRTVTLDVDVNNRTDRLEWCSCYYHGNFSLNAAFEIKLH
             1330      1340      1350      1360      1370      1380

     1360      1370      1380      1390      1400      1410        
pF1KSD WMAVTAAVLFEMVQGWHRKATSCGFLLVPVLEGPFALPSYLYGDPLRAQLFIPLNISCLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WMAVTAAVLFEMVQGWHRKATSCGFLLVPVLEGPFALPSYLYGDPLRAQLFIPLNISCLL
             1390      1400      1410      1420      1430      1440

     1420      1430      1440      1450      1460      1470        
pF1KSD KEGSEHLFDSFEPETYWDRMHLFQEAIAHRFGFVQDKYSASAFNFPAENKPQYIHVTGTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KEGSEHLFDSFEPETYWDRMHLFQEAIAHRFGFVQDKYSASAFNFPAENKPQYIHVTGTV
             1450      1460      1470      1480      1490      1500

     1480      1490      1500      1510      1520      1530        
pF1KSD FLQLPYSKRKFSGQQRRRRNSTSSTNQNMFCEERVGYNWAYNTMLTKTWRSSATGDEKFA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLQLPYSKRKFSGQQRRRRNSTSSTNQNMFCEERVGYNWAYNTMLTKTWRSSATGDEKFA
             1510      1520      1530      1540      1550      1560

     1540      1550      1560      1570  
pF1KSD DRLLKDFTDFCINRDNRLVTFWTSCLEKMHASAP
       ::::::::::::::::::::::::::::::::::
NP_001 DRLLKDFTDFCINRDNRLVTFWTSCLEKMHASAP
             1570      1580      1590    

>>XP_016884598 (OMIM: 604364,614191) PREDICTED: DEP doma  (1594 aa)
 initn: 7295 init1: 7295 opt: 7302  Z-score: 7487.3  bits: 1398.2 E(85289):    0
Smith-Waterman score: 10572; 98.6% identity (98.6% similar) in 1594 aa overlap (1-1572:1-1594)

               10        20        30        40        50        60
pF1KSD MRTTKVYKLVIHKKGFGGSDDELVVNPKVFPHIKLGDIVEIAHPNDEYSPLLLQVKSLKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MRTTKVYKLVIHKKGFGGSDDELVVNPKVFPHIKLGDIVEIAHPNDEYSPLLLQVKSLKE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD DLQKETISVDQTVTQVFRLRPYQDVYVNVVDPKDVTLDLVELTFKDQYIGRGDMWRLKKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLQKETISVDQTVTQVFRLRPYQDVYVNVVDPKDVTLDLVELTFKDQYIGRGDMWRLKKS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD LVSTCAYITQKVEFAGIRAQAGELWVKNEKVMCGYISEDTRVVFRSTSAMVYIFIQMSCE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVSTCAYITQKVEFAGIRAQAGELWVKNEKVMCGYISEDTRVVFRSTSAMVYIFIQMSCE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD MWDFDIYGDLYFEKAVNGFLADLFTKWKEKNCSHEVTVVLFSRTFYDAKSVDEFPEINRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MWDFDIYGDLYFEKAVNGFLADLFTKWKEKNCSHEVTVVLFSRTFYDAKSVDEFPEINRA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD SIRQDHKGRFYEDFYKVVVQNERREEWTSLLVTIKKLFIQYPVLVRLEQAEGFPQGDNST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SIRQDHKGRFYEDFYKVVVQNERREEWTSLLVTIKKLFIQYPVLVRLEQAEGFPQGDNST
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD SAQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFEVDRLLMILTKQRMIDN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SAQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFEVDRLLMILTKQRMIDN
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD GIGVDLVCMGEQPLHAVPLFKLHNRSAPRDSRLGDDYNIPHWINHSFYTSKSQLFCNSFT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GIGVDLVCMGEQPLHAVPLFKLHNRSAPRDSRLGDDYNIPHWINHSFYTSKSQLFCNSFT
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD PRIKLAGKKPASEKAKNGRDTSLGSPKESENALPIQVDYDAYDAQVFRLPGPSRAQCLTT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRIKLAGKKPASEKAKNGRDTSLGSPKESENALPIQVDYDAYDAQVFRLPGPSRAQCLTT
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD CRSVRERESHSRKSASSCDVSSSPSLPSRTLPTEEVRSQASDDSSLGKSANILMIPHPHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CRSVRERESHSRKSASSCDVSSSPSLPSRTLPTEEVRSQASDDSSLGKSANILMIPHPHL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD HQYEVSSSLGYTSTRDVLENMMEPPQRDSSAPGRFHVGSAESMLHVRPGGYTPQRALINP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HQYEVSSSLGYTSTRDVLENMMEPPQRDSSAPGRFHVGSAESMLHVRPGGYTPQRALINP
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD FAPSRMPMKLTSNRRRWMHTFPVGPSGEAIQIHHQTRQNMAELQGSGQRDPTHSSAELLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FAPSRMPMKLTSNRRRWMHTFPVGPSGEAIQIHHQTRQNMAELQGSGQRDPTHSSAELLE
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD LAYHEAAGRHSNSRQPGDGMSFLNFSGTEELSVGLLSNSGAGMNPRTQNKDSLEDSVSTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAYHEAAGRHSNSRQPGDGMSFLNFSGTEELSVGLLSNSGAGMNPRTQNKDSLEDSVSTS
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD PDPMPGFCCTVGVDWKSLTTPACLPLTTDYFPDRQGLQNDYTEGCYDLLPEADIDRRDED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PDPMPGFCCTVGVDWKSLTTPACLPLTTDYFPDRQGLQNDYTEGCYDLLPEADIDRRDED
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KSD GVQMTAQQVFEEFICQRLMQGYQIIVQPKTQKPNPAVPPPLSSSPLYSRGLVSRNRPEEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GVQMTAQQVFEEFICQRLMQGYQIIVQPKTQKPNPAVPPPLSSSPLYSRGLVSRNRPEEE
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KSD DQYWLSMGRTFHKVTLKDKMITVTRYLPKYPYESAQIHYTYSLCPSHSDSEFVSCWVEFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DQYWLSMGRTFHKVTLKDKMITVTRYLPKYPYESAQIHYTYSLCPSHSDSEFVSCWVEFS
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KSD HERLEEYKWNYLDQYICSAGSEDFSLIESLKFWRTRFLLLPACVTATKRITEGEAHCDIY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HERLEEYKWNYLDQYICSAGSEDFSLIESLKFWRTRFLLLPACVTATKRITEGEAHCDIY
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KSD GDRPRADEDEWQLLDGFVRFVEGLNRIRRRHRSDRMMRKGTAMKGLQMTGPISTHSLEST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDRPRADEDEWQLLDGFVRFVEGLNRIRRRHRSDRMMRKGTAMKGLQMTGPISTHSLEST
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070          
pF1KSD APPVGKKGTSALSALLEMEASQKCLGEQQAAVHGGKSSAQSAESSSVAMTPTYMDSPRK-
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: 
XP_016 APPVGKKGTSALSALLEMEASQKCLGEQQAAVHGGKSSAQSAESSSVAMTPTYMDSPRKD
             1030      1040      1050      1060      1070      1080

                         1080      1090      1100      1110        
pF1KSD ---------------------VSVDQTATPMLDGTSLGICTGQSMDRGNSQTFGNSQNIG
                            :::::::::::::::::::::::::::::::::::::::
XP_016 GAFFMEFVRSPRTASSAFYPQVSVDQTATPMLDGTSLGICTGQSMDRGNSQTFGNSQNIG
             1090      1100      1110      1120      1130      1140

     1120      1130      1140      1150      1160      1170        
pF1KSD EQGYSSTNSSDSSSQQLVASSLTSSSTLTEILEAMKHPSTGVQLLSEQKGLSPYCFISAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQGYSSTNSSDSSSQQLVASSLTSSSTLTEILEAMKHPSTGVQLLSEQKGLSPYCFISAE
             1150      1160      1170      1180      1190      1200

     1180      1190      1200      1210      1220      1230        
pF1KSD VVHWLVNHVEGIQTQAMAIDIMQKMLEEQLITHASGEAWRTFIYGFYFYKIVTDKEPDRV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVHWLVNHVEGIQTQAMAIDIMQKMLEEQLITHASGEAWRTFIYGFYFYKIVTDKEPDRV
             1210      1220      1230      1240      1250      1260

     1240      1250      1260      1270      1280      1290        
pF1KSD AMQQPATTWHTAGVDDFASFQRKWFEVAFVAEELVHSEIPAFLLPWLPSRPASYASRHSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AMQQPATTWHTAGVDDFASFQRKWFEVAFVAEELVHSEIPAFLLPWLPSRPASYASRHSS
             1270      1280      1290      1300      1310      1320

     1300      1310      1320      1330      1340      1350        
pF1KSD FSRSFGGRSQAAALLAATVPEQRTVTLDVDVNNRTDRLEWCSCYYHGNFSLNAAFEIKLH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSRSFGGRSQAAALLAATVPEQRTVTLDVDVNNRTDRLEWCSCYYHGNFSLNAAFEIKLH
             1330      1340      1350      1360      1370      1380

     1360      1370      1380      1390      1400      1410        
pF1KSD WMAVTAAVLFEMVQGWHRKATSCGFLLVPVLEGPFALPSYLYGDPLRAQLFIPLNISCLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WMAVTAAVLFEMVQGWHRKATSCGFLLVPVLEGPFALPSYLYGDPLRAQLFIPLNISCLL
             1390      1400      1410      1420      1430      1440

     1420      1430      1440      1450      1460      1470        
pF1KSD KEGSEHLFDSFEPETYWDRMHLFQEAIAHRFGFVQDKYSASAFNFPAENKPQYIHVTGTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KEGSEHLFDSFEPETYWDRMHLFQEAIAHRFGFVQDKYSASAFNFPAENKPQYIHVTGTV
             1450      1460      1470      1480      1490      1500

     1480      1490      1500      1510      1520      1530        
pF1KSD FLQLPYSKRKFSGQQRRRRNSTSSTNQNMFCEERVGYNWAYNTMLTKTWRSSATGDEKFA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLQLPYSKRKFSGQQRRRRNSTSSTNQNMFCEERVGYNWAYNTMLTKTWRSSATGDEKFA
             1510      1520      1530      1540      1550      1560

     1540      1550      1560      1570  
pF1KSD DRLLKDFTDFCINRDNRLVTFWTSCLEKMHASAP
       ::::::::::::::::::::::::::::::::::
XP_016 DRLLKDFTDFCINRDNRLVTFWTSCLEKMHASAP
             1570      1580      1590    

>>NP_001229826 (OMIM: 604364,614191) DEP domain-containi  (1503 aa)
 initn: 9960 init1: 5790 opt: 5790  Z-score: 5935.6  bits: 1111.0 E(85289):    0
Smith-Waterman score: 9913; 94.4% identity (94.5% similar) in 1581 aa overlap (1-1572:1-1503)

               10        20        30        40        50        60
pF1KSD MRTTKVYKLVIHKKGFGGSDDELVVNPKVFPHIKLGDIVEIAHPNDEYSPLLLQVKSLKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRTTKVYKLVIHKKGFGGSDDELVVNPKVFPHIKLGDIVEIAHPNDEYSPLLLQVKSLKE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD DLQKETISVDQTVTQVFRLRPYQDVYVNVVDPKDVTLDLVELTFKDQYIGRGDMWRLKKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLQKETISVDQTVTQVFRLRPYQDVYVNVVDPKDVTLDLVELTFKDQYIGRGDMWRLKKS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD LVSTCAYITQKVEFAGIRAQAGELWVKNEKVMCGYISEDTRVVFRSTSAMVYIFIQMSCE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVSTCAYITQKVEFAGIRAQAGELWVKNEKVMCGYISEDTRVVFRSTSAMVYIFIQMSCE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD MWDFDIYGDLYFEKAVNGFLADLFTKWKEKNCSHEVTVVLFSRTFYDAKSVDEFPEINRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MWDFDIYGDLYFEKAVNGFLADLFTKWKEKNCSHEVTVVLFSRTFYDAKSVDEFPEINRA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD SIRQDHKGRFYEDFYKVVVQNERREEWTSLLVTIKKLFIQYPVLVRLEQAEGFPQGDNST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SIRQDHKGRFYEDFYKVVVQNERREEWTSLLVTIKKLFIQYPVLVRLEQAEGFPQGDNST
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD SAQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFEVDRLLMILTKQRMIDN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SAQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFEVDRLLMILTKQRMIDN
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD GIGVDLVCMGEQPLHAVPLFKLHNRSAPRDSRLGDDYNIPHWINHSFYTSKSQLFCNSFT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GIGVDLVCMGEQPLHAVPLFKLHNRSAPRDSRLGDDYNIPHWINHSFYTSKSQLFCNSFT
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD PRIKLAGKKPASEKAKNGRDTSLGSPKESENALPIQVDYDAYDAQVFRLPGPSRAQCLTT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PRIKLAGKKPASEKAKNGRDTSLGSPKESENALPIQVDYDAYDAQVFRLPGPSRAQCLTT
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD CRSVRERESHSRKSASSCDVSSSPSLPSRTLPTEEVRSQASDDSSLGKSANILMIPHPHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CRSVRERESHSRKSASSCDVSSSPSLPSRTLPTEEVRSQASDDSSLGKSANILMIPHPHL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD HQYEVSSSLGYTSTRDVLENMMEPPQRDSSAPGRFHVGSAESMLHVRPGGYTPQRALINP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HQYEVSSSLGYTSTRDVLENMMEPPQRDSSAPGRFHVGSAESMLHVRPGGYTPQRALINP
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD FAPSRMPMKLTSNRRRWMHTFPVGPSGEAIQIHHQTRQNMAELQGSGQRDPTHSSAELLE
       ::::::::::::::::::::::::                                    
NP_001 FAPSRMPMKLTSNRRRWMHTFPVG------------------------------------
              610       620                                        

              670       680       690       700       710       720
pF1KSD LAYHEAAGRHSNSRQPGDGMSFLNFSGTEELSVGLLSNSGAGMNPRTQNKDSLEDSVSTS
                                                 ::::::::::::::::::
NP_001 ------------------------------------------MNPRTQNKDSLEDSVSTS
                                                    630       640  

                       730       740       750       760       770 
pF1KSD PDPM---------PGFCCTVGVDWKSLTTPACLPLTTDYFPDRQGLQNDYTEGCYDLLPE
       :::.         :::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDPILTLSAPPVVPGFCCTVGVDWKSLTTPACLPLTTDYFPDRQGLQNDYTEGCYDLLPE
            650       660       670       680       690       700  

             780       790       800       810       820       830 
pF1KSD ADIDRRDEDGVQMTAQQVFEEFICQRLMQGYQIIVQPKTQKPNPAVPPPLSSSPLYSRGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADIDRRDEDGVQMTAQQVFEEFICQRLMQGYQIIVQPKTQKPNPAVPPPLSSSPLYSRGL
            710       720       730       740       750       760  

             840       850       860       870       880       890 
pF1KSD VSRNRPEEEDQYWLSMGRTFHKVTLKDKMITVTRYLPKYPYESAQIHYTYSLCPSHSDSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSRNRPEEEDQYWLSMGRTFHKVTLKDKMITVTRYLPKYPYESAQIHYTYSLCPSHSDSE
            770       780       790       800       810       820  

             900       910       920       930       940       950 
pF1KSD FVSCWVEFSHERLEEYKWNYLDQYICSAGSEDFSLIESLKFWRTRFLLLPACVTATKRIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FVSCWVEFSHERLEEYKWNYLDQYICSAGSEDFSLIESLKFWRTRFLLLPACVTATKRIT
            830       840       850       860       870       880  

             960       970       980       990      1000      1010 
pF1KSD EGEAHCDIYGDRPRADEDEWQLLDGFVRFVEGLNRIRRRHRSDRMMRKGTAMKGLQMTGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGEAHCDIYGDRPRADEDEWQLLDGFVRFVEGLNRIRRRHRSDRMMRKGTAMKGLQMTGP
            890       900       910       920       930       940  

            1020      1030      1040      1050      1060      1070 
pF1KSD ISTHSLESTAPPVGKKGTSALSALLEMEASQKCLGEQQAAVHGGKSSAQSAESSSVAMTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ISTHSLESTAPPVGKKGTSALSALLEMEASQKCLGEQQAAVHGGKSSAQSAESSSVAMTP
            950       960       970       980       990      1000  

            1080      1090      1100      1110      1120      1130 
pF1KSD TYMDSPRKVSVDQTATPMLDGTSLGICTGQSMDRGNSQTFGNSQNIGEQGYSSTNSSDSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TYMDSPRKVSVDQTATPMLDGTSLGICTGQSMDRGNSQTFGNSQNIGEQGYSSTNSSDSS
           1010      1020      1030      1040      1050      1060  

            1140      1150      1160      1170      1180      1190 
pF1KSD SQQLVASSLTSSSTLTEILEAMKHPSTGVQLLSEQKGLSPYCFISAEVVHWLVNHVEGIQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQQLVASSLTSSSTLTEILEAMKHPSTGVQLLSEQKGLSPYCFISAEVVHWLVNHVEGIQ
           1070      1080      1090      1100      1110      1120  

            1200      1210      1220      1230      1240      1250 
pF1KSD TQAMAIDIMQKMLEEQLITHASGEAWRTFIYGFYFYKIVTDKEPDRVAMQQPATTWHTAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TQAMAIDIMQKMLEEQLITHASGEAWRTFIYGFYFYKIVTDKEPDRVAMQQPATTWHTAG
           1130      1140      1150      1160      1170      1180  

            1260      1270      1280      1290      1300      1310 
pF1KSD VDDFASFQRKWFEVAFVAEELVHSEIPAFLLPWLPSRPASYASRHSSFSRSFGGRSQAAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VDDFASFQRKWFEVAFVAEELVHSEIPAFLLPWLPSRPASYASRHSSFSRSFGGRSQAAA
           1190      1200      1210      1220      1230      1240  

            1320      1330      1340      1350      1360      1370 
pF1KSD LLAATVPEQRTVTLDVDVNNRTDRLEWCSCYYHGNFSLNAAFEIKLHWMAVTAAVLFEMV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLAATVPEQRTVTLDVDVNNRTDRLEWCSCYYHGNFSLNAAFEIKLHWMAVTAAVLFEMV
           1250      1260      1270      1280      1290      1300  

            1380      1390      1400      1410      1420      1430 
pF1KSD QGWHRKATSCGFLLVPVLEGPFALPSYLYGDPLRAQLFIPLNISCLLKEGSEHLFDSFEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QGWHRKATSCGFLLVPVLEGPFALPSYLYGDPLRAQLFIPLNISCLLKEGSEHLFDSFEP
           1310      1320      1330      1340      1350      1360  

            1440      1450      1460      1470      1480      1490 
pF1KSD ETYWDRMHLFQEAIAHRFGFVQDKYSASAFNFPAENKPQYIHVTGTVFLQLPYSKRKFSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETYWDRMHLFQEAIAHRFGFVQDKYSASAFNFPAENKPQYIHVTGTVFLQLPYSKRKFSG
           1370      1380      1390      1400      1410      1420  

            1500      1510      1520      1530      1540      1550 
pF1KSD QQRRRRNSTSSTNQNMFCEERVGYNWAYNTMLTKTWRSSATGDEKFADRLLKDFTDFCIN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQRRRRNSTSSTNQNMFCEERVGYNWAYNTMLTKTWRSSATGDEKFADRLLKDFTDFCIN
           1430      1440      1450      1460      1470      1480  

            1560      1570  
pF1KSD RDNRLVTFWTSCLEKMHASAP
       :::::::::::::::::::::
NP_001 RDNRLVTFWTSCLEKMHASAP
           1490      1500   

>>XP_011528865 (OMIM: 604364,614191) PREDICTED: DEP doma  (1503 aa)
 initn: 9960 init1: 5790 opt: 5790  Z-score: 5935.6  bits: 1111.0 E(85289):    0
Smith-Waterman score: 9913; 94.4% identity (94.5% similar) in 1581 aa overlap (1-1572:1-1503)

               10        20        30        40        50        60
pF1KSD MRTTKVYKLVIHKKGFGGSDDELVVNPKVFPHIKLGDIVEIAHPNDEYSPLLLQVKSLKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRTTKVYKLVIHKKGFGGSDDELVVNPKVFPHIKLGDIVEIAHPNDEYSPLLLQVKSLKE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD DLQKETISVDQTVTQVFRLRPYQDVYVNVVDPKDVTLDLVELTFKDQYIGRGDMWRLKKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLQKETISVDQTVTQVFRLRPYQDVYVNVVDPKDVTLDLVELTFKDQYIGRGDMWRLKKS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD LVSTCAYITQKVEFAGIRAQAGELWVKNEKVMCGYISEDTRVVFRSTSAMVYIFIQMSCE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVSTCAYITQKVEFAGIRAQAGELWVKNEKVMCGYISEDTRVVFRSTSAMVYIFIQMSCE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD MWDFDIYGDLYFEKAVNGFLADLFTKWKEKNCSHEVTVVLFSRTFYDAKSVDEFPEINRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MWDFDIYGDLYFEKAVNGFLADLFTKWKEKNCSHEVTVVLFSRTFYDAKSVDEFPEINRA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD SIRQDHKGRFYEDFYKVVVQNERREEWTSLLVTIKKLFIQYPVLVRLEQAEGFPQGDNST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SIRQDHKGRFYEDFYKVVVQNERREEWTSLLVTIKKLFIQYPVLVRLEQAEGFPQGDNST
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD SAQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFEVDRLLMILTKQRMIDN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SAQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFEVDRLLMILTKQRMIDN
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD GIGVDLVCMGEQPLHAVPLFKLHNRSAPRDSRLGDDYNIPHWINHSFYTSKSQLFCNSFT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GIGVDLVCMGEQPLHAVPLFKLHNRSAPRDSRLGDDYNIPHWINHSFYTSKSQLFCNSFT
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD PRIKLAGKKPASEKAKNGRDTSLGSPKESENALPIQVDYDAYDAQVFRLPGPSRAQCLTT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PRIKLAGKKPASEKAKNGRDTSLGSPKESENALPIQVDYDAYDAQVFRLPGPSRAQCLTT
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD CRSVRERESHSRKSASSCDVSSSPSLPSRTLPTEEVRSQASDDSSLGKSANILMIPHPHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CRSVRERESHSRKSASSCDVSSSPSLPSRTLPTEEVRSQASDDSSLGKSANILMIPHPHL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD HQYEVSSSLGYTSTRDVLENMMEPPQRDSSAPGRFHVGSAESMLHVRPGGYTPQRALINP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HQYEVSSSLGYTSTRDVLENMMEPPQRDSSAPGRFHVGSAESMLHVRPGGYTPQRALINP
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD FAPSRMPMKLTSNRRRWMHTFPVGPSGEAIQIHHQTRQNMAELQGSGQRDPTHSSAELLE
       ::::::::::::::::::::::::                                    
XP_011 FAPSRMPMKLTSNRRRWMHTFPVG------------------------------------
              610       620                                        

              670       680       690       700       710       720
pF1KSD LAYHEAAGRHSNSRQPGDGMSFLNFSGTEELSVGLLSNSGAGMNPRTQNKDSLEDSVSTS
                                                 ::::::::::::::::::
XP_011 ------------------------------------------MNPRTQNKDSLEDSVSTS
                                                    630       640  

                       730       740       750       760       770 
pF1KSD PDPM---------PGFCCTVGVDWKSLTTPACLPLTTDYFPDRQGLQNDYTEGCYDLLPE
       :::.         :::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDPILTLSAPPVVPGFCCTVGVDWKSLTTPACLPLTTDYFPDRQGLQNDYTEGCYDLLPE
            650       660       670       680       690       700  

             780       790       800       810       820       830 
pF1KSD ADIDRRDEDGVQMTAQQVFEEFICQRLMQGYQIIVQPKTQKPNPAVPPPLSSSPLYSRGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ADIDRRDEDGVQMTAQQVFEEFICQRLMQGYQIIVQPKTQKPNPAVPPPLSSSPLYSRGL
            710       720       730       740       750       760  

             840       850       860       870       880       890 
pF1KSD VSRNRPEEEDQYWLSMGRTFHKVTLKDKMITVTRYLPKYPYESAQIHYTYSLCPSHSDSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSRNRPEEEDQYWLSMGRTFHKVTLKDKMITVTRYLPKYPYESAQIHYTYSLCPSHSDSE
            770       780       790       800       810       820  

             900       910       920       930       940       950 
pF1KSD FVSCWVEFSHERLEEYKWNYLDQYICSAGSEDFSLIESLKFWRTRFLLLPACVTATKRIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FVSCWVEFSHERLEEYKWNYLDQYICSAGSEDFSLIESLKFWRTRFLLLPACVTATKRIT
            830       840       850       860       870       880  

             960       970       980       990      1000      1010 
pF1KSD EGEAHCDIYGDRPRADEDEWQLLDGFVRFVEGLNRIRRRHRSDRMMRKGTAMKGLQMTGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGEAHCDIYGDRPRADEDEWQLLDGFVRFVEGLNRIRRRHRSDRMMRKGTAMKGLQMTGP
            890       900       910       920       930       940  

            1020      1030      1040      1050      1060      1070 
pF1KSD ISTHSLESTAPPVGKKGTSALSALLEMEASQKCLGEQQAAVHGGKSSAQSAESSSVAMTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ISTHSLESTAPPVGKKGTSALSALLEMEASQKCLGEQQAAVHGGKSSAQSAESSSVAMTP
            950       960       970       980       990      1000  

            1080      1090      1100      1110      1120      1130 
pF1KSD TYMDSPRKVSVDQTATPMLDGTSLGICTGQSMDRGNSQTFGNSQNIGEQGYSSTNSSDSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TYMDSPRKVSVDQTATPMLDGTSLGICTGQSMDRGNSQTFGNSQNIGEQGYSSTNSSDSS
           1010      1020      1030      1040      1050      1060  

            1140      1150      1160      1170      1180      1190 
pF1KSD SQQLVASSLTSSSTLTEILEAMKHPSTGVQLLSEQKGLSPYCFISAEVVHWLVNHVEGIQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQQLVASSLTSSSTLTEILEAMKHPSTGVQLLSEQKGLSPYCFISAEVVHWLVNHVEGIQ
           1070      1080      1090      1100      1110      1120  

            1200      1210      1220      1230      1240      1250 
pF1KSD TQAMAIDIMQKMLEEQLITHASGEAWRTFIYGFYFYKIVTDKEPDRVAMQQPATTWHTAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TQAMAIDIMQKMLEEQLITHASGEAWRTFIYGFYFYKIVTDKEPDRVAMQQPATTWHTAG
           1130      1140      1150      1160      1170      1180  

            1260      1270      1280      1290      1300      1310 
pF1KSD VDDFASFQRKWFEVAFVAEELVHSEIPAFLLPWLPSRPASYASRHSSFSRSFGGRSQAAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VDDFASFQRKWFEVAFVAEELVHSEIPAFLLPWLPSRPASYASRHSSFSRSFGGRSQAAA
           1190      1200      1210      1220      1230      1240  

            1320      1330      1340      1350      1360      1370 
pF1KSD LLAATVPEQRTVTLDVDVNNRTDRLEWCSCYYHGNFSLNAAFEIKLHWMAVTAAVLFEMV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLAATVPEQRTVTLDVDVNNRTDRLEWCSCYYHGNFSLNAAFEIKLHWMAVTAAVLFEMV
           1250      1260      1270      1280      1290      1300  

            1380      1390      1400      1410      1420      1430 
pF1KSD QGWHRKATSCGFLLVPVLEGPFALPSYLYGDPLRAQLFIPLNISCLLKEGSEHLFDSFEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QGWHRKATSCGFLLVPVLEGPFALPSYLYGDPLRAQLFIPLNISCLLKEGSEHLFDSFEP
           1310      1320      1330      1340      1350      1360  

            1440      1450      1460      1470      1480      1490 
pF1KSD ETYWDRMHLFQEAIAHRFGFVQDKYSASAFNFPAENKPQYIHVTGTVFLQLPYSKRKFSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETYWDRMHLFQEAIAHRFGFVQDKYSASAFNFPAENKPQYIHVTGTVFLQLPYSKRKFSG
           1370      1380      1390      1400      1410      1420  

            1500      1510      1520      1530      1540      1550 
pF1KSD QQRRRRNSTSSTNQNMFCEERVGYNWAYNTMLTKTWRSSATGDEKFADRLLKDFTDFCIN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQRRRRNSTSSTNQNMFCEERVGYNWAYNTMLTKTWRSSATGDEKFADRLLKDFTDFCIN
           1430      1440      1450      1460      1470      1480  

            1560      1570  
pF1KSD RDNRLVTFWTSCLEKMHASAP
       :::::::::::::::::::::
XP_011 RDNRLVTFWTSCLEKMHASAP
           1490      1500   

>>XP_016884599 (OMIM: 604364,614191) PREDICTED: DEP doma  (1581 aa)
 initn: 5790 init1: 5790 opt: 5790  Z-score: 5935.3  bits: 1111.0 E(85289):    0
Smith-Waterman score: 10593; 99.4% identity (99.4% similar) in 1581 aa overlap (1-1572:1-1581)

               10        20        30        40        50        60
pF1KSD MRTTKVYKLVIHKKGFGGSDDELVVNPKVFPHIKLGDIVEIAHPNDEYSPLLLQVKSLKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MRTTKVYKLVIHKKGFGGSDDELVVNPKVFPHIKLGDIVEIAHPNDEYSPLLLQVKSLKE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD DLQKETISVDQTVTQVFRLRPYQDVYVNVVDPKDVTLDLVELTFKDQYIGRGDMWRLKKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLQKETISVDQTVTQVFRLRPYQDVYVNVVDPKDVTLDLVELTFKDQYIGRGDMWRLKKS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD LVSTCAYITQKVEFAGIRAQAGELWVKNEKVMCGYISEDTRVVFRSTSAMVYIFIQMSCE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVSTCAYITQKVEFAGIRAQAGELWVKNEKVMCGYISEDTRVVFRSTSAMVYIFIQMSCE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD MWDFDIYGDLYFEKAVNGFLADLFTKWKEKNCSHEVTVVLFSRTFYDAKSVDEFPEINRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MWDFDIYGDLYFEKAVNGFLADLFTKWKEKNCSHEVTVVLFSRTFYDAKSVDEFPEINRA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD SIRQDHKGRFYEDFYKVVVQNERREEWTSLLVTIKKLFIQYPVLVRLEQAEGFPQGDNST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SIRQDHKGRFYEDFYKVVVQNERREEWTSLLVTIKKLFIQYPVLVRLEQAEGFPQGDNST
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD SAQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFEVDRLLMILTKQRMIDN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SAQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFEVDRLLMILTKQRMIDN
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD GIGVDLVCMGEQPLHAVPLFKLHNRSAPRDSRLGDDYNIPHWINHSFYTSKSQLFCNSFT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GIGVDLVCMGEQPLHAVPLFKLHNRSAPRDSRLGDDYNIPHWINHSFYTSKSQLFCNSFT
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD PRIKLAGKKPASEKAKNGRDTSLGSPKESENALPIQVDYDAYDAQVFRLPGPSRAQCLTT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRIKLAGKKPASEKAKNGRDTSLGSPKESENALPIQVDYDAYDAQVFRLPGPSRAQCLTT
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD CRSVRERESHSRKSASSCDVSSSPSLPSRTLPTEEVRSQASDDSSLGKSANILMIPHPHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CRSVRERESHSRKSASSCDVSSSPSLPSRTLPTEEVRSQASDDSSLGKSANILMIPHPHL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD HQYEVSSSLGYTSTRDVLENMMEPPQRDSSAPGRFHVGSAESMLHVRPGGYTPQRALINP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HQYEVSSSLGYTSTRDVLENMMEPPQRDSSAPGRFHVGSAESMLHVRPGGYTPQRALINP
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD FAPSRMPMKLTSNRRRWMHTFPVGPSGEAIQIHHQTRQNMAELQGSGQRDPTHSSAELLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FAPSRMPMKLTSNRRRWMHTFPVGPSGEAIQIHHQTRQNMAELQGSGQRDPTHSSAELLE
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD LAYHEAAGRHSNSRQPGDGMSFLNFSGTEELSVGLLSNSGAGMNPRTQNKDSLEDSVSTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAYHEAAGRHSNSRQPGDGMSFLNFSGTEELSVGLLSNSGAGMNPRTQNKDSLEDSVSTS
              670       680       690       700       710       720

                       730       740       750       760       770 
pF1KSD PDPM---------PGFCCTVGVDWKSLTTPACLPLTTDYFPDRQGLQNDYTEGCYDLLPE
       :::.         :::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PDPILTLSAPPVVPGFCCTVGVDWKSLTTPACLPLTTDYFPDRQGLQNDYTEGCYDLLPE
              730       740       750       760       770       780

             780       790       800       810       820       830 
pF1KSD ADIDRRDEDGVQMTAQQVFEEFICQRLMQGYQIIVQPKTQKPNPAVPPPLSSSPLYSRGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ADIDRRDEDGVQMTAQQVFEEFICQRLMQGYQIIVQPKTQKPNPAVPPPLSSSPLYSRGL
              790       800       810       820       830       840

             840       850       860       870       880       890 
pF1KSD VSRNRPEEEDQYWLSMGRTFHKVTLKDKMITVTRYLPKYPYESAQIHYTYSLCPSHSDSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSRNRPEEEDQYWLSMGRTFHKVTLKDKMITVTRYLPKYPYESAQIHYTYSLCPSHSDSE
              850       860       870       880       890       900

             900       910       920       930       940       950 
pF1KSD FVSCWVEFSHERLEEYKWNYLDQYICSAGSEDFSLIESLKFWRTRFLLLPACVTATKRIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FVSCWVEFSHERLEEYKWNYLDQYICSAGSEDFSLIESLKFWRTRFLLLPACVTATKRIT
              910       920       930       940       950       960

             960       970       980       990      1000      1010 
pF1KSD EGEAHCDIYGDRPRADEDEWQLLDGFVRFVEGLNRIRRRHRSDRMMRKGTAMKGLQMTGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGEAHCDIYGDRPRADEDEWQLLDGFVRFVEGLNRIRRRHRSDRMMRKGTAMKGLQMTGP
              970       980       990      1000      1010      1020

            1020      1030      1040      1050      1060      1070 
pF1KSD ISTHSLESTAPPVGKKGTSALSALLEMEASQKCLGEQQAAVHGGKSSAQSAESSSVAMTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISTHSLESTAPPVGKKGTSALSALLEMEASQKCLGEQQAAVHGGKSSAQSAESSSVAMTP
             1030      1040      1050      1060      1070      1080

            1080      1090      1100      1110      1120      1130 
pF1KSD TYMDSPRKVSVDQTATPMLDGTSLGICTGQSMDRGNSQTFGNSQNIGEQGYSSTNSSDSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TYMDSPRKVSVDQTATPMLDGTSLGICTGQSMDRGNSQTFGNSQNIGEQGYSSTNSSDSS
             1090      1100      1110      1120      1130      1140

            1140      1150      1160      1170      1180      1190 
pF1KSD SQQLVASSLTSSSTLTEILEAMKHPSTGVQLLSEQKGLSPYCFISAEVVHWLVNHVEGIQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQQLVASSLTSSSTLTEILEAMKHPSTGVQLLSEQKGLSPYCFISAEVVHWLVNHVEGIQ
             1150      1160      1170      1180      1190      1200

            1200      1210      1220      1230      1240      1250 
pF1KSD TQAMAIDIMQKMLEEQLITHASGEAWRTFIYGFYFYKIVTDKEPDRVAMQQPATTWHTAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TQAMAIDIMQKMLEEQLITHASGEAWRTFIYGFYFYKIVTDKEPDRVAMQQPATTWHTAG
             1210      1220      1230      1240      1250      1260

            1260      1270      1280      1290      1300      1310 
pF1KSD VDDFASFQRKWFEVAFVAEELVHSEIPAFLLPWLPSRPASYASRHSSFSRSFGGRSQAAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VDDFASFQRKWFEVAFVAEELVHSEIPAFLLPWLPSRPASYASRHSSFSRSFGGRSQAAA
             1270      1280      1290      1300      1310      1320

            1320      1330      1340      1350      1360      1370 
pF1KSD LLAATVPEQRTVTLDVDVNNRTDRLEWCSCYYHGNFSLNAAFEIKLHWMAVTAAVLFEMV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLAATVPEQRTVTLDVDVNNRTDRLEWCSCYYHGNFSLNAAFEIKLHWMAVTAAVLFEMV
             1330      1340      1350      1360      1370      1380

            1380      1390      1400      1410      1420      1430 
pF1KSD QGWHRKATSCGFLLVPVLEGPFALPSYLYGDPLRAQLFIPLNISCLLKEGSEHLFDSFEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QGWHRKATSCGFLLVPVLEGPFALPSYLYGDPLRAQLFIPLNISCLLKEGSEHLFDSFEP
             1390      1400      1410      1420      1430      1440

            1440      1450      1460      1470      1480      1490 
pF1KSD ETYWDRMHLFQEAIAHRFGFVQDKYSASAFNFPAENKPQYIHVTGTVFLQLPYSKRKFSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETYWDRMHLFQEAIAHRFGFVQDKYSASAFNFPAENKPQYIHVTGTVFLQLPYSKRKFSG
             1450      1460      1470      1480      1490      1500

            1500      1510      1520      1530      1540      1550 
pF1KSD QQRRRRNSTSSTNQNMFCEERVGYNWAYNTMLTKTWRSSATGDEKFADRLLKDFTDFCIN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQRRRRNSTSSTNQNMFCEERVGYNWAYNTMLTKTWRSSATGDEKFADRLLKDFTDFCIN
             1510      1520      1530      1540      1550      1560

            1560      1570  
pF1KSD RDNRLVTFWTSCLEKMHASAP
       :::::::::::::::::::::
XP_016 RDNRLVTFWTSCLEKMHASAP
             1570      1580 

>>XP_011528860 (OMIM: 604364,614191) PREDICTED: DEP doma  (1581 aa)
 initn: 5790 init1: 5790 opt: 5790  Z-score: 5935.3  bits: 1111.0 E(85289):    0
Smith-Waterman score: 10593; 99.4% identity (99.4% similar) in 1581 aa overlap (1-1572:1-1581)

               10        20        30        40        50        60
pF1KSD MRTTKVYKLVIHKKGFGGSDDELVVNPKVFPHIKLGDIVEIAHPNDEYSPLLLQVKSLKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRTTKVYKLVIHKKGFGGSDDELVVNPKVFPHIKLGDIVEIAHPNDEYSPLLLQVKSLKE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD DLQKETISVDQTVTQVFRLRPYQDVYVNVVDPKDVTLDLVELTFKDQYIGRGDMWRLKKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLQKETISVDQTVTQVFRLRPYQDVYVNVVDPKDVTLDLVELTFKDQYIGRGDMWRLKKS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD LVSTCAYITQKVEFAGIRAQAGELWVKNEKVMCGYISEDTRVVFRSTSAMVYIFIQMSCE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVSTCAYITQKVEFAGIRAQAGELWVKNEKVMCGYISEDTRVVFRSTSAMVYIFIQMSCE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD MWDFDIYGDLYFEKAVNGFLADLFTKWKEKNCSHEVTVVLFSRTFYDAKSVDEFPEINRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MWDFDIYGDLYFEKAVNGFLADLFTKWKEKNCSHEVTVVLFSRTFYDAKSVDEFPEINRA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD SIRQDHKGRFYEDFYKVVVQNERREEWTSLLVTIKKLFIQYPVLVRLEQAEGFPQGDNST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SIRQDHKGRFYEDFYKVVVQNERREEWTSLLVTIKKLFIQYPVLVRLEQAEGFPQGDNST
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD SAQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFEVDRLLMILTKQRMIDN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SAQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFEVDRLLMILTKQRMIDN
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD GIGVDLVCMGEQPLHAVPLFKLHNRSAPRDSRLGDDYNIPHWINHSFYTSKSQLFCNSFT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GIGVDLVCMGEQPLHAVPLFKLHNRSAPRDSRLGDDYNIPHWINHSFYTSKSQLFCNSFT
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD PRIKLAGKKPASEKAKNGRDTSLGSPKESENALPIQVDYDAYDAQVFRLPGPSRAQCLTT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PRIKLAGKKPASEKAKNGRDTSLGSPKESENALPIQVDYDAYDAQVFRLPGPSRAQCLTT
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD CRSVRERESHSRKSASSCDVSSSPSLPSRTLPTEEVRSQASDDSSLGKSANILMIPHPHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CRSVRERESHSRKSASSCDVSSSPSLPSRTLPTEEVRSQASDDSSLGKSANILMIPHPHL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD HQYEVSSSLGYTSTRDVLENMMEPPQRDSSAPGRFHVGSAESMLHVRPGGYTPQRALINP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HQYEVSSSLGYTSTRDVLENMMEPPQRDSSAPGRFHVGSAESMLHVRPGGYTPQRALINP
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD FAPSRMPMKLTSNRRRWMHTFPVGPSGEAIQIHHQTRQNMAELQGSGQRDPTHSSAELLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FAPSRMPMKLTSNRRRWMHTFPVGPSGEAIQIHHQTRQNMAELQGSGQRDPTHSSAELLE
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD LAYHEAAGRHSNSRQPGDGMSFLNFSGTEELSVGLLSNSGAGMNPRTQNKDSLEDSVSTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAYHEAAGRHSNSRQPGDGMSFLNFSGTEELSVGLLSNSGAGMNPRTQNKDSLEDSVSTS
              670       680       690       700       710       720

                       730       740       750       760       770 
pF1KSD PDPM---------PGFCCTVGVDWKSLTTPACLPLTTDYFPDRQGLQNDYTEGCYDLLPE
       :::.         :::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDPILTLSAPPVVPGFCCTVGVDWKSLTTPACLPLTTDYFPDRQGLQNDYTEGCYDLLPE
              730       740       750       760       770       780

             780       790       800       810       820       830 
pF1KSD ADIDRRDEDGVQMTAQQVFEEFICQRLMQGYQIIVQPKTQKPNPAVPPPLSSSPLYSRGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ADIDRRDEDGVQMTAQQVFEEFICQRLMQGYQIIVQPKTQKPNPAVPPPLSSSPLYSRGL
              790       800       810       820       830       840

             840       850       860       870       880       890 
pF1KSD VSRNRPEEEDQYWLSMGRTFHKVTLKDKMITVTRYLPKYPYESAQIHYTYSLCPSHSDSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSRNRPEEEDQYWLSMGRTFHKVTLKDKMITVTRYLPKYPYESAQIHYTYSLCPSHSDSE
              850       860       870       880       890       900

             900       910       920       930       940       950 
pF1KSD FVSCWVEFSHERLEEYKWNYLDQYICSAGSEDFSLIESLKFWRTRFLLLPACVTATKRIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FVSCWVEFSHERLEEYKWNYLDQYICSAGSEDFSLIESLKFWRTRFLLLPACVTATKRIT
              910       920       930       940       950       960

             960       970       980       990      1000      1010 
pF1KSD EGEAHCDIYGDRPRADEDEWQLLDGFVRFVEGLNRIRRRHRSDRMMRKGTAMKGLQMTGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGEAHCDIYGDRPRADEDEWQLLDGFVRFVEGLNRIRRRHRSDRMMRKGTAMKGLQMTGP
              970       980       990      1000      1010      1020

            1020      1030      1040      1050      1060      1070 
pF1KSD ISTHSLESTAPPVGKKGTSALSALLEMEASQKCLGEQQAAVHGGKSSAQSAESSSVAMTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ISTHSLESTAPPVGKKGTSALSALLEMEASQKCLGEQQAAVHGGKSSAQSAESSSVAMTP
             1030      1040      1050      1060      1070      1080

            1080      1090      1100      1110      1120      1130 
pF1KSD TYMDSPRKVSVDQTATPMLDGTSLGICTGQSMDRGNSQTFGNSQNIGEQGYSSTNSSDSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TYMDSPRKVSVDQTATPMLDGTSLGICTGQSMDRGNSQTFGNSQNIGEQGYSSTNSSDSS
             1090      1100      1110      1120      1130      1140

            1140      1150      1160      1170      1180      1190 
pF1KSD SQQLVASSLTSSSTLTEILEAMKHPSTGVQLLSEQKGLSPYCFISAEVVHWLVNHVEGIQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQQLVASSLTSSSTLTEILEAMKHPSTGVQLLSEQKGLSPYCFISAEVVHWLVNHVEGIQ
             1150      1160      1170      1180      1190      1200

            1200      1210      1220      1230      1240      1250 
pF1KSD TQAMAIDIMQKMLEEQLITHASGEAWRTFIYGFYFYKIVTDKEPDRVAMQQPATTWHTAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TQAMAIDIMQKMLEEQLITHASGEAWRTFIYGFYFYKIVTDKEPDRVAMQQPATTWHTAG
             1210      1220      1230      1240      1250      1260

            1260      1270      1280      1290      1300      1310 
pF1KSD VDDFASFQRKWFEVAFVAEELVHSEIPAFLLPWLPSRPASYASRHSSFSRSFGGRSQAAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VDDFASFQRKWFEVAFVAEELVHSEIPAFLLPWLPSRPASYASRHSSFSRSFGGRSQAAA
             1270      1280      1290      1300      1310      1320

            1320      1330      1340      1350      1360      1370 
pF1KSD LLAATVPEQRTVTLDVDVNNRTDRLEWCSCYYHGNFSLNAAFEIKLHWMAVTAAVLFEMV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLAATVPEQRTVTLDVDVNNRTDRLEWCSCYYHGNFSLNAAFEIKLHWMAVTAAVLFEMV
             1330      1340      1350      1360      1370      1380

            1380      1390      1400      1410      1420      1430 
pF1KSD QGWHRKATSCGFLLVPVLEGPFALPSYLYGDPLRAQLFIPLNISCLLKEGSEHLFDSFEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QGWHRKATSCGFLLVPVLEGPFALPSYLYGDPLRAQLFIPLNISCLLKEGSEHLFDSFEP
             1390      1400      1410      1420      1430      1440

            1440      1450      1460      1470      1480      1490 
pF1KSD ETYWDRMHLFQEAIAHRFGFVQDKYSASAFNFPAENKPQYIHVTGTVFLQLPYSKRKFSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETYWDRMHLFQEAIAHRFGFVQDKYSASAFNFPAENKPQYIHVTGTVFLQLPYSKRKFSG
             1450      1460      1470      1480      1490      1500

            1500      1510      1520      1530      1540      1550 
pF1KSD QQRRRRNSTSSTNQNMFCEERVGYNWAYNTMLTKTWRSSATGDEKFADRLLKDFTDFCIN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQRRRRNSTSSTNQNMFCEERVGYNWAYNTMLTKTWRSSATGDEKFADRLLKDFTDFCIN
             1510      1520      1530      1540      1550      1560

            1560      1570  
pF1KSD RDNRLVTFWTSCLEKMHASAP
       :::::::::::::::::::::
XP_011 RDNRLVTFWTSCLEKMHASAP
             1570      1580 




1572 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 02:28:50 2016 done: Thu Nov  3 02:28:52 2016
 Total Scan time: 14.490 Total Display time:  0.870

Function used was FASTA [36.3.4 Apr, 2011]
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