Result of FASTA (omim) for
pF1KSDA0457
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA0457, 832 aa
1>>>pF1KSDA0457 832 - 832 aa - 832 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.3005+/-0.000363; mu= 2.6955+/- 0.022
mean_var=248.5831+/-49.678, 0's: 0 Z-trim(121.4): 70 B-trim: 0 in 0/55
Lambda= 0.081346
statistics sampled from 37868 (37940) to 37868 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.767), E-opt: 0.2 (0.445), width: 16
Scan time: 12.480
The best scores are: opt bits E(85289)
NP_001012975 (OMIM: 181500,604906,605210) disrupte ( 832) 5543 664.3 6.4e-190
NP_001158010 (OMIM: 181500,604906,605210) disrupte ( 803) 5004 601.0 6.9e-171
NP_061132 (OMIM: 181500,604906,605210) disrupted i ( 854) 5004 601.0 7.2e-171
NP_001158014 (OMIM: 181500,604906,605210) disrupte ( 681) 4544 547.0 1.1e-154
NP_001158013 (OMIM: 181500,604906,605210) disrupte ( 695) 4429 533.5 1.3e-150
NP_001158011 (OMIM: 181500,604906,605210) disrupte ( 755) 4420 532.4 2.8e-150
NP_001158016 (OMIM: 181500,604906,605210) disrupte ( 662) 4418 532.2 3e-150
NP_001012977 (OMIM: 181500,604906,605210) disrupte ( 678) 4418 532.2 3.1e-150
NP_001158017 (OMIM: 181500,604906,605210) disrupte ( 579) 3814 461.2 5.9e-129
NP_001158021 (OMIM: 181500,604906,605210) disrupte ( 547) 3697 447.5 7.7e-125
NP_001158020 (OMIM: 181500,604906,605210) disrupte ( 551) 3697 447.5 7.7e-125
NP_001158018 (OMIM: 181500,604906,605210) disrupte ( 559) 3697 447.5 7.8e-125
NP_001158019 (OMIM: 181500,604906,605210) disrupte ( 559) 3697 447.5 7.8e-125
NP_001158023 (OMIM: 181500,604906,605210) disrupte ( 423) 2899 353.7 9.9e-97
NP_001158012 (OMIM: 181500,604906,605210) disrupte ( 732) 2900 354.0 1.4e-96
NP_001158009 (OMIM: 181500,604906,605210) disrupte ( 886) 2596 318.4 8.7e-86
NP_001158024 (OMIM: 181500,604906,605210) disrupte ( 387) 2585 316.8 1.1e-85
NP_001158025 (OMIM: 181500,604906,605210) disrupte ( 387) 2585 316.8 1.1e-85
NP_001158026 (OMIM: 181500,604906,605210) disrupte ( 375) 2584 316.7 1.2e-85
NP_001158022 (OMIM: 181500,604906,605210) disrupte ( 429) 2578 316.1 2.2e-85
NP_001158027 (OMIM: 181500,604906,605210) disrupte ( 356) 2436 299.3 2e-80
NP_001012976 (OMIM: 181500,604906,605210) disrupte ( 369) 2436 299.3 2e-80
NP_001158028 (OMIM: 181500,604906,605210) disrupte ( 201) 1119 144.6 4.3e-34
>>NP_001012975 (OMIM: 181500,604906,605210) disrupted in (832 aa)
initn: 5543 init1: 5543 opt: 5543 Z-score: 3530.6 bits: 664.3 E(85289): 6.4e-190
Smith-Waterman score: 5543; 99.9% identity (100.0% similar) in 832 aa overlap (1-832:1-832)
10 20 30 40 50 60
pF1KSD MPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD VGTLFRFPGGVSGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGTLFRFPGGVSGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD QLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD ELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD SPQEMGAKAASLDGPHEDPRCLSQPFSLLATRVSADLAQAARNSSRPERDMHSLPDMDPG
:::::::::::::::::::::::.::::::::::::::::::::::::::::::::::::
NP_001 SPQEMGAKAASLDGPHEDPRCLSRPFSLLATRVSADLAQAARNSSRPERDMHSLPDMDPG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD SSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMEVISLRLKLQKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMEVISLRLKLQKL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD QEDAVENDDYDKAETLQQRLEDLEQEKISLHFQLPSRQPALSSFLGHLAAQVQAALRRGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEDAVENDDYDKAETLQQRLEDLEQEKISLHFQLPSRQPALSSFLGHLAAQVQAALRRGA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD TQQASGDDTHTPLRMEPRLLEPTAQDSLHVSITRRDWLLQEKQQLQKEIEALQARMFVLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TQQASGDDTHTPLRMEPRLLEPTAQDSLHVSITRRDWLLQEKQQLQKEIEALQARMFVLE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD AKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEVSKALQDTLASAGQIPFHAEPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEVSKALQDTLASAGQIPFHAEPP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD ETIRSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKVNDIETQLPALLEAKMHAISGNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETIRSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKVNDIETQLPALLEAKMHAISGNH
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD FWTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVKKLGSVKEDYNRLRREVEHQETAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FWTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVKKLGSVKEDYNRLRREVEHQETAY
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD ETSVKENTMKYMETLKNKLCSCKCPLLGKVWEADLEACRLLIQSLQLQEARGSLSVEDER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETSVKENTMKYMETLKNKLCSCKCPLLGKVWEADLEACRLLIQSLQLQEARGSLSVEDER
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD QMDDLEGAAPPIPPRLHSEDKRKTPLKESYILSAELGEKCEDIGKKLLYLEDQLHTAIHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QMDDLEGAAPPIPPRLHSEDKRKTPLKESYILSAELGEKCEDIGKKLLYLEDQLHTAIHS
730 740 750 760 770 780
790 800 810 820 830
pF1KSD HDEDLIQSLRRELQMVKETLQAMILQLQPAKEAGEREAAASCMTAGVHEAQA
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HDEDLIQSLRRELQMVKETLQAMILQLQPAKEAGEREAAASCMTAGVHEAQA
790 800 810 820 830
>>NP_001158010 (OMIM: 181500,604906,605210) disrupted in (803 aa)
initn: 5004 init1: 5004 opt: 5004 Z-score: 3189.0 bits: 601.0 E(85289): 6.9e-171
Smith-Waterman score: 5004; 99.9% identity (100.0% similar) in 747 aa overlap (1-747:1-747)
10 20 30 40 50 60
pF1KSD MPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD VGTLFRFPGGVSGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGTLFRFPGGVSGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD QLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD ELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD SPQEMGAKAASLDGPHEDPRCLSQPFSLLATRVSADLAQAARNSSRPERDMHSLPDMDPG
:::::::::::::::::::::::.::::::::::::::::::::::::::::::::::::
NP_001 SPQEMGAKAASLDGPHEDPRCLSRPFSLLATRVSADLAQAARNSSRPERDMHSLPDMDPG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD SSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMEVISLRLKLQKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMEVISLRLKLQKL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD QEDAVENDDYDKAETLQQRLEDLEQEKISLHFQLPSRQPALSSFLGHLAAQVQAALRRGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEDAVENDDYDKAETLQQRLEDLEQEKISLHFQLPSRQPALSSFLGHLAAQVQAALRRGA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD TQQASGDDTHTPLRMEPRLLEPTAQDSLHVSITRRDWLLQEKQQLQKEIEALQARMFVLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TQQASGDDTHTPLRMEPRLLEPTAQDSLHVSITRRDWLLQEKQQLQKEIEALQARMFVLE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD AKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEVSKALQDTLASAGQIPFHAEPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEVSKALQDTLASAGQIPFHAEPP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD ETIRSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKVNDIETQLPALLEAKMHAISGNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETIRSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKVNDIETQLPALLEAKMHAISGNH
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD FWTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVKKLGSVKEDYNRLRREVEHQETAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FWTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVKKLGSVKEDYNRLRREVEHQETAY
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD ETSVKENTMKYMETLKNKLCSCKCPLLGKVWEADLEACRLLIQSLQLQEARGSLSVEDER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETSVKENTMKYMETLKNKLCSCKCPLLGKVWEADLEACRLLIQSLQLQEARGSLSVEDER
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD QMDDLEGAAPPIPPRLHSEDKRKTPLKESYILSAELGEKCEDIGKKLLYLEDQLHTAIHS
:::::::::::::::::::::::::::
NP_001 QMDDLEGAAPPIPPRLHSEDKRKTPLKVLEEWKTHLIPSLHCAGGEQKEVCPFHMASRGD
730 740 750 760 770 780
>>NP_061132 (OMIM: 181500,604906,605210) disrupted in sc (854 aa)
initn: 5004 init1: 5004 opt: 5004 Z-score: 3188.6 bits: 601.0 E(85289): 7.2e-171
Smith-Waterman score: 5489; 97.3% identity (97.4% similar) in 854 aa overlap (1-832:1-854)
10 20 30 40 50 60
pF1KSD MPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 MPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD VGTLFRFPGGVSGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 VGTLFRFPGGVSGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD QLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 QLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD ELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 ELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD SPQEMGAKAASLDGPHEDPRCLSQPFSLLATRVSADLAQAARNSSRPERDMHSLPDMDPG
:::::::::::::::::::::::.::::::::::::::::::::::::::::::::::::
NP_061 SPQEMGAKAASLDGPHEDPRCLSRPFSLLATRVSADLAQAARNSSRPERDMHSLPDMDPG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD SSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMEVISLRLKLQKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 SSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMEVISLRLKLQKL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD QEDAVENDDYDKAETLQQRLEDLEQEKISLHFQLPSRQPALSSFLGHLAAQVQAALRRGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 QEDAVENDDYDKAETLQQRLEDLEQEKISLHFQLPSRQPALSSFLGHLAAQVQAALRRGA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD TQQASGDDTHTPLRMEPRLLEPTAQDSLHVSITRRDWLLQEKQQLQKEIEALQARMFVLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 TQQASGDDTHTPLRMEPRLLEPTAQDSLHVSITRRDWLLQEKQQLQKEIEALQARMFVLE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD AKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEVSKALQDTLASAGQIPFHAEPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 AKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEVSKALQDTLASAGQIPFHAEPP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD ETIRSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKVNDIETQLPALLEAKMHAISGNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 ETIRSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKVNDIETQLPALLEAKMHAISGNH
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD FWTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVKKLGSVKEDYNRLRREVEHQETAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 FWTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVKKLGSVKEDYNRLRREVEHQETAY
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD ETSVKENTMKYMETLKNKLCSCKCPLLGKVWEADLEACRLLIQSLQLQEARGSLSVEDER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 ETSVKENTMKYMETLKNKLCSCKCPLLGKVWEADLEACRLLIQSLQLQEARGSLSVEDER
670 680 690 700 710 720
730 740 750
pF1KSD QMDDLEGAAPPIPPRLHSEDKRKTPLK----------------------ESYILSAELGE
::::::::::::::::::::::::::: :::::::::::
NP_061 QMDDLEGAAPPIPPRLHSEDKRKTPLKVLEEWKTHLIPSLHCAGGEQKEESYILSAELGE
730 740 750 760 770 780
760 770 780 790 800 810
pF1KSD KCEDIGKKLLYLEDQLHTAIHSHDEDLIQSLRRELQMVKETLQAMILQLQPAKEAGEREA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 KCEDIGKKLLYLEDQLHTAIHSHDEDLIQSLRRELQMVKETLQAMILQLQPAKEAGEREA
790 800 810 820 830 840
820 830
pF1KSD AASCMTAGVHEAQA
::::::::::::::
NP_061 AASCMTAGVHEAQA
850
>>NP_001158014 (OMIM: 181500,604906,605210) disrupted in (681 aa)
initn: 4544 init1: 4544 opt: 4544 Z-score: 2898.2 bits: 547.0 E(85289): 1.1e-154
Smith-Waterman score: 4544; 99.9% identity (100.0% similar) in 680 aa overlap (1-680:1-680)
10 20 30 40 50 60
pF1KSD MPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD VGTLFRFPGGVSGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGTLFRFPGGVSGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD QLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD ELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD SPQEMGAKAASLDGPHEDPRCLSQPFSLLATRVSADLAQAARNSSRPERDMHSLPDMDPG
:::::::::::::::::::::::.::::::::::::::::::::::::::::::::::::
NP_001 SPQEMGAKAASLDGPHEDPRCLSRPFSLLATRVSADLAQAARNSSRPERDMHSLPDMDPG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD SSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMEVISLRLKLQKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMEVISLRLKLQKL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD QEDAVENDDYDKAETLQQRLEDLEQEKISLHFQLPSRQPALSSFLGHLAAQVQAALRRGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEDAVENDDYDKAETLQQRLEDLEQEKISLHFQLPSRQPALSSFLGHLAAQVQAALRRGA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD TQQASGDDTHTPLRMEPRLLEPTAQDSLHVSITRRDWLLQEKQQLQKEIEALQARMFVLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TQQASGDDTHTPLRMEPRLLEPTAQDSLHVSITRRDWLLQEKQQLQKEIEALQARMFVLE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD AKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEVSKALQDTLASAGQIPFHAEPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEVSKALQDTLASAGQIPFHAEPP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD ETIRSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKVNDIETQLPALLEAKMHAISGNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETIRSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKVNDIETQLPALLEAKMHAISGNH
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD FWTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVKKLGSVKEDYNRLRREVEHQETAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FWTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVKKLGSVKEDYNRLRREVEHQETAY
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD ETSVKENTMKYMETLKNKLCSCKCPLLGKVWEADLEACRLLIQSLQLQEARGSLSVEDER
::::::::::::::::::::
NP_001 ETSVKENTMKYMETLKNKLCR
670 680
>>NP_001158013 (OMIM: 181500,604906,605210) disrupted in (695 aa)
initn: 4427 init1: 4427 opt: 4429 Z-score: 2825.1 bits: 533.5 E(85289): 1.3e-150
Smith-Waterman score: 4429; 97.5% identity (98.2% similar) in 682 aa overlap (1-682:1-680)
10 20 30 40 50 60
pF1KSD MPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD VGTLFRFPGGVSGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGTLFRFPGGVSGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD QLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD ELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD SPQEMGAKAASLDGPHEDPRCLSQPFSLLATRVSADLAQAARNSSRPERDMHSLPDMDPG
:::::::::::::::::::::::.::::::::::::::::::::::::::::::::::::
NP_001 SPQEMGAKAASLDGPHEDPRCLSRPFSLLATRVSADLAQAARNSSRPERDMHSLPDMDPG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD SSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMEVISLRLKLQKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMEVISLRLKLQKL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD QEDAVENDDYDKAETLQQRLEDLEQEKISLHFQLPSRQPALSSFLGHLAAQVQAALRRGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEDAVENDDYDKAETLQQRLEDLEQEKISLHFQLPSRQPALSSFLGHLAAQVQAALRRGA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD TQQASGDDTHTPLRMEPRLLEPTAQDSLHVSITRRDWLLQEKQQLQKEIEALQARMFVLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TQQASGDDTHTPLRMEPRLLEPTAQDSLHVSITRRDWLLQEKQQLQKEIEALQARMFVLE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD AKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEVSKALQDTLASAGQIPFHAEPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEVSKALQDTLASAGQIPFHAEPP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD ETIRSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKVNDIETQLPALLEAKMHAISGNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETIRSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKVNDIETQLPALLEAKMHAISGNH
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD FWTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVKKLGSVKEDYNRLRREVEHQETAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FWTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVKKLGSVKEDYNRLRREVEHQETAY
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD ETSVKENTMKYMETLKNKLCSCKCPLLGKVWEADLEACRLLIQSLQLQEARGSLSVEDER
.:: . . : :: .:
NP_001 AASV--HCLGKCGKLTWKLVDCLSRAYSSRKPGEACL
670 680 690
>>NP_001158011 (OMIM: 181500,604906,605210) disrupted in (755 aa)
initn: 4456 init1: 4420 opt: 4420 Z-score: 2818.9 bits: 532.4 E(85289): 2.8e-150
Smith-Waterman score: 4420; 99.7% identity (100.0% similar) in 661 aa overlap (1-661:1-661)
10 20 30 40 50 60
pF1KSD MPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD VGTLFRFPGGVSGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGTLFRFPGGVSGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD QLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD ELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD SPQEMGAKAASLDGPHEDPRCLSQPFSLLATRVSADLAQAARNSSRPERDMHSLPDMDPG
:::::::::::::::::::::::.::::::::::::::::::::::::::::::::::::
NP_001 SPQEMGAKAASLDGPHEDPRCLSRPFSLLATRVSADLAQAARNSSRPERDMHSLPDMDPG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD SSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMEVISLRLKLQKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMEVISLRLKLQKL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD QEDAVENDDYDKAETLQQRLEDLEQEKISLHFQLPSRQPALSSFLGHLAAQVQAALRRGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEDAVENDDYDKAETLQQRLEDLEQEKISLHFQLPSRQPALSSFLGHLAAQVQAALRRGA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD TQQASGDDTHTPLRMEPRLLEPTAQDSLHVSITRRDWLLQEKQQLQKEIEALQARMFVLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TQQASGDDTHTPLRMEPRLLEPTAQDSLHVSITRRDWLLQEKQQLQKEIEALQARMFVLE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD AKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEVSKALQDTLASAGQIPFHAEPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEVSKALQDTLASAGQIPFHAEPP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD ETIRSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKVNDIETQLPALLEAKMHAISGNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETIRSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKVNDIETQLPALLEAKMHAISGNH
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD FWTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVKKLGSVKEDYNRLRREVEHQETAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FWTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVKKLGSVKEDYNRLRREVEHQETAY
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD ETSVKENTMKYMETLKNKLCSCKCPLLGKVWEADLEACRLLIQSLQLQEARGSLSVEDER
.
NP_001 DGVSLCRPVWSAVVRSCSLQPLPPEFKQFSCLSLRSSWDYRCPPPCLANFVFLVEMGFYH
670 680 690 700 710 720
>>NP_001158016 (OMIM: 181500,604906,605210) disrupted in (662 aa)
initn: 4418 init1: 4418 opt: 4418 Z-score: 2818.4 bits: 532.2 E(85289): 3e-150
Smith-Waterman score: 4418; 99.8% identity (100.0% similar) in 660 aa overlap (1-660:1-660)
10 20 30 40 50 60
pF1KSD MPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD VGTLFRFPGGVSGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGTLFRFPGGVSGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD QLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD ELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD SPQEMGAKAASLDGPHEDPRCLSQPFSLLATRVSADLAQAARNSSRPERDMHSLPDMDPG
:::::::::::::::::::::::.::::::::::::::::::::::::::::::::::::
NP_001 SPQEMGAKAASLDGPHEDPRCLSRPFSLLATRVSADLAQAARNSSRPERDMHSLPDMDPG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD SSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMEVISLRLKLQKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMEVISLRLKLQKL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD QEDAVENDDYDKAETLQQRLEDLEQEKISLHFQLPSRQPALSSFLGHLAAQVQAALRRGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEDAVENDDYDKAETLQQRLEDLEQEKISLHFQLPSRQPALSSFLGHLAAQVQAALRRGA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD TQQASGDDTHTPLRMEPRLLEPTAQDSLHVSITRRDWLLQEKQQLQKEIEALQARMFVLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TQQASGDDTHTPLRMEPRLLEPTAQDSLHVSITRRDWLLQEKQQLQKEIEALQARMFVLE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD AKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEVSKALQDTLASAGQIPFHAEPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEVSKALQDTLASAGQIPFHAEPP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD ETIRSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKVNDIETQLPALLEAKMHAISGNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETIRSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKVNDIETQLPALLEAKMHAISGNH
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD FWTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVKKLGSVKEDYNRLRREVEHQETAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FWTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVKKLGSVKEDYNRLRREVEHQETAY
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD ETSVKENTMKYMETLKNKLCSCKCPLLGKVWEADLEACRLLIQSLQLQEARGSLSVEDER
NP_001 GR
>>NP_001012977 (OMIM: 181500,604906,605210) disrupted in (678 aa)
initn: 4418 init1: 4418 opt: 4418 Z-score: 2818.3 bits: 532.2 E(85289): 3.1e-150
Smith-Waterman score: 4418; 99.8% identity (100.0% similar) in 660 aa overlap (1-660:1-660)
10 20 30 40 50 60
pF1KSD MPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD VGTLFRFPGGVSGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGTLFRFPGGVSGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD QLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD ELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD SPQEMGAKAASLDGPHEDPRCLSQPFSLLATRVSADLAQAARNSSRPERDMHSLPDMDPG
:::::::::::::::::::::::.::::::::::::::::::::::::::::::::::::
NP_001 SPQEMGAKAASLDGPHEDPRCLSRPFSLLATRVSADLAQAARNSSRPERDMHSLPDMDPG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD SSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMEVISLRLKLQKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMEVISLRLKLQKL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD QEDAVENDDYDKAETLQQRLEDLEQEKISLHFQLPSRQPALSSFLGHLAAQVQAALRRGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEDAVENDDYDKAETLQQRLEDLEQEKISLHFQLPSRQPALSSFLGHLAAQVQAALRRGA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD TQQASGDDTHTPLRMEPRLLEPTAQDSLHVSITRRDWLLQEKQQLQKEIEALQARMFVLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TQQASGDDTHTPLRMEPRLLEPTAQDSLHVSITRRDWLLQEKQQLQKEIEALQARMFVLE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD AKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEVSKALQDTLASAGQIPFHAEPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEVSKALQDTLASAGQIPFHAEPP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD ETIRSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKVNDIETQLPALLEAKMHAISGNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETIRSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKVNDIETQLPALLEAKMHAISGNH
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD FWTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVKKLGSVKEDYNRLRREVEHQETAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FWTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVKKLGSVKEDYNRLRREVEHQETAY
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD ETSVKENTMKYMETLKNKLCSCKCPLLGKVWEADLEACRLLIQSLQLQEARGSLSVEDER
NP_001 GYKYCDAESWTQRSQQLA
670
>>NP_001158017 (OMIM: 181500,604906,605210) disrupted in (579 aa)
initn: 3850 init1: 3814 opt: 3814 Z-score: 2436.1 bits: 461.2 E(85289): 5.9e-129
Smith-Waterman score: 3814; 97.9% identity (99.1% similar) in 576 aa overlap (1-576:1-576)
10 20 30 40 50 60
pF1KSD MPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD VGTLFRFPGGVSGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGTLFRFPGGVSGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD QLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD ELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD SPQEMGAKAASLDGPHEDPRCLSQPFSLLATRVSADLAQAARNSSRPERDMHSLPDMDPG
:::::::::::::::::::::::.::::::::::::::::::::::::::::::::::::
NP_001 SPQEMGAKAASLDGPHEDPRCLSRPFSLLATRVSADLAQAARNSSRPERDMHSLPDMDPG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD SSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMEVISLRLKLQKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMEVISLRLKLQKL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD QEDAVENDDYDKAETLQQRLEDLEQEKISLHFQLPSRQPALSSFLGHLAAQVQAALRRGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEDAVENDDYDKAETLQQRLEDLEQEKISLHFQLPSRQPALSSFLGHLAAQVQAALRRGA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD TQQASGDDTHTPLRMEPRLLEPTAQDSLHVSITRRDWLLQEKQQLQKEIEALQARMFVLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TQQASGDDTHTPLRMEPRLLEPTAQDSLHVSITRRDWLLQEKQQLQKEIEALQARMFVLE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD AKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEVSKALQDTLASAGQIPFHAEPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEVSKALQDTLASAGQIPFHAEPP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD ETIRSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKVNDIETQLPALLEAKMHAISGNH
::::::::::::::::::::::: .: .. .. :.
NP_001 ETIRSLQERIKSLNLSLKEITTKETISGRLKTSPRRLDH
550 560 570
610 620 630 640 650 660
pF1KSD FWTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVKKLGSVKEDYNRLRREVEHQETAY
>>NP_001158021 (OMIM: 181500,604906,605210) disrupted in (547 aa)
initn: 3697 init1: 3697 opt: 3697 Z-score: 2362.3 bits: 447.5 E(85289): 7.7e-125
Smith-Waterman score: 3697; 99.8% identity (100.0% similar) in 544 aa overlap (1-544:1-544)
10 20 30 40 50 60
pF1KSD MPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD VGTLFRFPGGVSGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGTLFRFPGGVSGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD QLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD ELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD SPQEMGAKAASLDGPHEDPRCLSQPFSLLATRVSADLAQAARNSSRPERDMHSLPDMDPG
:::::::::::::::::::::::.::::::::::::::::::::::::::::::::::::
NP_001 SPQEMGAKAASLDGPHEDPRCLSRPFSLLATRVSADLAQAARNSSRPERDMHSLPDMDPG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD SSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMEVISLRLKLQKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMEVISLRLKLQKL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD QEDAVENDDYDKAETLQQRLEDLEQEKISLHFQLPSRQPALSSFLGHLAAQVQAALRRGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEDAVENDDYDKAETLQQRLEDLEQEKISLHFQLPSRQPALSSFLGHLAAQVQAALRRGA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD TQQASGDDTHTPLRMEPRLLEPTAQDSLHVSITRRDWLLQEKQQLQKEIEALQARMFVLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TQQASGDDTHTPLRMEPRLLEPTAQDSLHVSITRRDWLLQEKQQLQKEIEALQARMFVLE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD AKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEVSKALQDTLASAGQIPFHAEPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEVSKALQDTLASAGQIPFHAEPP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD ETIRSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKVNDIETQLPALLEAKMHAISGNH
::::
NP_001 ETIRRYC
832 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 01:47:24 2016 done: Thu Nov 3 01:47:26 2016
Total Scan time: 12.480 Total Display time: 0.240
Function used was FASTA [36.3.4 Apr, 2011]