Result of FASTA (omim) for pF1KSDA0319
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KSDA0319, 1072 aa
  1>>>pF1KSDA0319 1072 - 1072 aa - 1072 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 10.8089+/-0.000435; mu= -5.8267+/- 0.027
 mean_var=226.1842+/-46.339, 0's: 0 Z-trim(116.7): 55  B-trim: 0 in 0/59
 Lambda= 0.085279
 statistics sampled from 27984 (28034) to 27984 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.672), E-opt: 0.2 (0.329), width:  16
 Scan time: 13.490

The best scores are:                                      opt bits E(85289)
NP_001161847 (OMIM: 600202,609269) dyslexia-associ (1072) 7106 888.3       0
XP_011513327 (OMIM: 600202,609269) PREDICTED: dysl (1072) 7106 888.3       0
NP_055624 (OMIM: 600202,609269) dyslexia-associate (1072) 7106 888.3       0
NP_001161846 (OMIM: 600202,609269) dyslexia-associ (1063) 6993 874.4       0
XP_016867030 (OMIM: 600202,609269) PREDICTED: dysl (1063) 6993 874.4       0
XP_016867034 (OMIM: 600202,609269) PREDICTED: dysl (1027) 6821 853.2       0
XP_011513328 (OMIM: 600202,609269) PREDICTED: dysl (1027) 6821 853.2       0
NP_001161848 (OMIM: 600202,609269) dyslexia-associ (1027) 6821 853.2       0
XP_016867031 (OMIM: 600202,609269) PREDICTED: dysl (1047) 6720 840.8       0
XP_016867035 (OMIM: 600202,609269) PREDICTED: dysl ( 986) 6301 789.2       0
XP_016867039 (OMIM: 600202,609269) PREDICTED: dysl ( 978) 6296 788.6       0
XP_016867036 (OMIM: 600202,609269) PREDICTED: dysl ( 978) 6296 788.6       0
XP_016867038 (OMIM: 600202,609269) PREDICTED: dysl ( 978) 6296 788.6       0
XP_016867037 (OMIM: 600202,609269) PREDICTED: dysl ( 978) 6296 788.6       0
NP_001161849 (OMIM: 600202,609269) dyslexia-associ (1011) 6294 788.4       0
XP_016867042 (OMIM: 600202,609269) PREDICTED: dysl ( 920) 6033 756.2 1.9e-217
XP_016867041 (OMIM: 600202,609269) PREDICTED: dysl ( 920) 6033 756.2 1.9e-217
XP_016867040 (OMIM: 600202,609269) PREDICTED: dysl ( 937) 5967 748.1 5.3e-215
XP_016867032 (OMIM: 600202,609269) PREDICTED: dysl (1039) 4729 595.8 4.1e-169
XP_016867033 (OMIM: 600202,609269) PREDICTED: dysl (1039) 4729 595.8 4.1e-169
NP_001239257 (OMIM: 600202,609269) dyslexia-associ ( 483) 3195 407.0 1.3e-112
NP_079150 (OMIM: 613535) dyslexia-associated prote (1049) 2959 378.1 1.5e-103
XP_011540481 (OMIM: 613535) PREDICTED: dyslexia-as (1049) 2959 378.1 1.5e-103
XP_006710970 (OMIM: 613535) PREDICTED: dyslexia-as (1049) 2959 378.1 1.5e-103
XP_006710972 (OMIM: 613535) PREDICTED: dyslexia-as (1049) 2959 378.1 1.5e-103
XP_016857855 (OMIM: 613535) PREDICTED: dyslexia-as (1054) 2945 376.3  5e-103
XP_016857858 (OMIM: 613535) PREDICTED: dyslexia-as (1054) 2945 376.3  5e-103
XP_016857857 (OMIM: 613535) PREDICTED: dyslexia-as (1054) 2945 376.3  5e-103
XP_016857856 (OMIM: 613535) PREDICTED: dyslexia-as (1054) 2945 376.3  5e-103
XP_006710973 (OMIM: 613535) PREDICTED: dyslexia-as ( 691) 2708 347.1   2e-94
XP_016857865 (OMIM: 613535) PREDICTED: dyslexia-as ( 691) 2708 347.1   2e-94
XP_016857864 (OMIM: 613535) PREDICTED: dyslexia-as ( 696) 2694 345.4 6.7e-94
XP_016857863 (OMIM: 613535) PREDICTED: dyslexia-as ( 696) 2694 345.4 6.7e-94
XP_011540482 (OMIM: 613535) PREDICTED: dyslexia-as ( 950) 2628 337.3 2.5e-91
XP_016857861 (OMIM: 613535) PREDICTED: dyslexia-as ( 950) 2628 337.3 2.5e-91
XP_016857859 (OMIM: 613535) PREDICTED: dyslexia-as ( 955) 2614 335.6 8.2e-91
XP_016857860 (OMIM: 613535) PREDICTED: dyslexia-as ( 955) 2614 335.6 8.2e-91
XP_016857866 (OMIM: 613535) PREDICTED: dyslexia-as ( 592) 2377 306.4 3.2e-82
XP_016857862 (OMIM: 613535) PREDICTED: dyslexia-as ( 853) 2249 290.7 2.4e-77
XP_016857867 (OMIM: 613535) PREDICTED: dyslexia-as ( 491) 1775 232.3 5.3e-60


>>NP_001161847 (OMIM: 600202,609269) dyslexia-associated  (1072 aa)
 initn: 7106 init1: 7106 opt: 7106  Z-score: 4737.3  bits: 888.3 E(85289):    0
Smith-Waterman score: 7106; 99.8% identity (99.9% similar) in 1072 aa overlap (1-1072:1-1072)

               10        20        30        40        50        60
pF1KSD MAPPTGVLSSLLLLVTIAGCARKQCSEGRTYSNAVISPNLETTRIMRVSHTFPVVDCTAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAPPTGVLSSLLLLVTIAGCARKQCSEGRTYSNAVISPNLETTRIMRVSHTFPVVDCTAA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD CCDLSSCDLAWWFEGRCYLVSCPHKENCEPKKMGPIRSYLTFVLRPVQRPAQLLDYGDMM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CCDLSSCDLAWWFEGRCYLVSCPHKENCEPKKMGPIRSYLTFVLRPVQRPAQLLDYGDMM
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD LNRGSPSGIWGDSPEDIRKDLPFLGKDWGLEEMSEYADDYRELEKDLLQPSGKQEPRGSA
       ::::::::::::::::::::: ::::::::::::::.:::::::::::::::::::::::
NP_001 LNRGSPSGIWGDSPEDIRKDLTFLGKDWGLEEMSEYSDDYRELEKDLLQPSGKQEPRGSA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD EYTDWGLLPGSEGAFNSSVGDSPAVPAETQQDPELHYLNESASTPAPKLPERSVLLPLPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EYTDWGLLPGSEGAFNSSVGDSPAVPAETQQDPELHYLNESASTPAPKLPERSVLLPLPT
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD TPSSGEVLEKEKASQLQEQSSNSSGKEVLMPSHSLPPASLELSSVTVEKSPVLTVTPGST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPSSGEVLEKEKASQLQEQSSNSSGKEVLMPSHSLPPASLELSSVTVEKSPVLTVTPGST
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD EHSIPTPPTSAAPSESTPSELPISPTTAPRTVKELTVSAGDNLIITLPDNEVELKAFVAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EHSIPTPPTSAAPSESTPSELPISPTTAPRTVKELTVSAGDNLIITLPDNEVELKAFVAP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD APPVETTYNYEWNLISHPTDYQGEIKQGHKQTLNLSQLSVGLYVFKVTVSSENAFGEGFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APPVETTYNYEWNLISHPTDYQGEIKQGHKQTLNLSQLSVGLYVFKVTVSSENAFGEGFV
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD NVTVKPARRVNLPPVAVVSPQLQELTLPLTSALIDGSQSTDDTEIVSYHWEEINGPFIEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NVTVKPARRVNLPPVAVVSPQLQELTLPLTSALIDGSQSTDDTEIVSYHWEEINGPFIEE
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD KTSVDSPVLRLSNLDPGNYSFRLTVTDSDGATNSTTAALIVNNAVDYPPVANAGPNHTIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KTSVDSPVLRLSNLDPGNYSFRLTVTDSDGATNSTTAALIVNNAVDYPPVANAGPNHTIT
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD LPQNSITLNGNQSSDDHQIVLYEWSLGPGSEGKHVVMQGVQTPYLHLSAMQEGDYTFQLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPQNSITLNGNQSSDDHQIVLYEWSLGPGSEGKHVVMQGVQTPYLHLSAMQEGDYTFQLK
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD VTDSSRQQSTAVVTVIVQPENNRPPVAVAGPDKELIFPVESATLDGSSSSDDHGIVFYHW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTDSSRQQSTAVVTVIVQPENNRPPVAVAGPDKELIFPVESATLDGSSSSDDHGIVFYHW
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD EHVRGPSAVEMENIDKAIATVTGLQVGTYHFRLTVKDQQGLSSTSTLTVAVKKENNSPPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EHVRGPSAVEMENIDKAIATVTGLQVGTYHFRLTVKDQQGLSSTSTLTVAVKKENNSPPR
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD ARAGGRHVLVLPNNSITLDGSRSTDDQRIVSYLWIRDGQSPAAGDVIDGSDHSVALQLTN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARAGGRHVLVLPNNSITLDGSRSTDDQRIVSYLWIRDGQSPAAGDVIDGSDHSVALQLTN
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KSD LVEGVYTFHLRVTDSQGASDTDTATVEVQPDPRKSGLVELTLQVGVGQLTEQRKDTLVRQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVEGVYTFHLRVTDSQGASDTDTATVEVQPDPRKSGLVELTLQVGVGQLTEQRKDTLVRQ
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KSD LAVLLNVLDSDIKVQKIRAHSDLSTVIVFYVQSRPPFKVLKAAEVARNLHMRLSKEKADF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAVLLNVLDSDIKVQKIRAHSDLSTVIVFYVQSRPPFKVLKAAEVARNLHMRLSKEKADF
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KSD LLFKVLRVDTAGCLLKCSGHGHCDPLTKRCICSHLWMENLIQRYIWDGESNCEWSIFYVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLFKVLRVDTAGCLLKCSGHGHCDPLTKRCICSHLWMENLIQRYIWDGESNCEWSIFYVT
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KSD VLAFTLIVLTGGFTWLCICCCKRQKRTKIRKKTKYTILDNMDEQERMELRPKYGIKHRST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLAFTLIVLTGGFTWLCICCCKRQKRTKIRKKTKYTILDNMDEQERMELRPKYGIKHRST
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070  
pF1KSD EHNSSLMVSESEFDSDQDTIFSREKMERGNPKVSMNGSIRNGASFSYCSKDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EHNSSLMVSESEFDSDQDTIFSREKMERGNPKVSMNGSIRNGASFSYCSKDR
             1030      1040      1050      1060      1070  

>>XP_011513327 (OMIM: 600202,609269) PREDICTED: dyslexia  (1072 aa)
 initn: 7106 init1: 7106 opt: 7106  Z-score: 4737.3  bits: 888.3 E(85289):    0
Smith-Waterman score: 7106; 99.8% identity (99.9% similar) in 1072 aa overlap (1-1072:1-1072)

               10        20        30        40        50        60
pF1KSD MAPPTGVLSSLLLLVTIAGCARKQCSEGRTYSNAVISPNLETTRIMRVSHTFPVVDCTAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAPPTGVLSSLLLLVTIAGCARKQCSEGRTYSNAVISPNLETTRIMRVSHTFPVVDCTAA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD CCDLSSCDLAWWFEGRCYLVSCPHKENCEPKKMGPIRSYLTFVLRPVQRPAQLLDYGDMM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CCDLSSCDLAWWFEGRCYLVSCPHKENCEPKKMGPIRSYLTFVLRPVQRPAQLLDYGDMM
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD LNRGSPSGIWGDSPEDIRKDLPFLGKDWGLEEMSEYADDYRELEKDLLQPSGKQEPRGSA
       ::::::::::::::::::::: ::::::::::::::.:::::::::::::::::::::::
XP_011 LNRGSPSGIWGDSPEDIRKDLTFLGKDWGLEEMSEYSDDYRELEKDLLQPSGKQEPRGSA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD EYTDWGLLPGSEGAFNSSVGDSPAVPAETQQDPELHYLNESASTPAPKLPERSVLLPLPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EYTDWGLLPGSEGAFNSSVGDSPAVPAETQQDPELHYLNESASTPAPKLPERSVLLPLPT
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD TPSSGEVLEKEKASQLQEQSSNSSGKEVLMPSHSLPPASLELSSVTVEKSPVLTVTPGST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TPSSGEVLEKEKASQLQEQSSNSSGKEVLMPSHSLPPASLELSSVTVEKSPVLTVTPGST
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD EHSIPTPPTSAAPSESTPSELPISPTTAPRTVKELTVSAGDNLIITLPDNEVELKAFVAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EHSIPTPPTSAAPSESTPSELPISPTTAPRTVKELTVSAGDNLIITLPDNEVELKAFVAP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD APPVETTYNYEWNLISHPTDYQGEIKQGHKQTLNLSQLSVGLYVFKVTVSSENAFGEGFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 APPVETTYNYEWNLISHPTDYQGEIKQGHKQTLNLSQLSVGLYVFKVTVSSENAFGEGFV
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD NVTVKPARRVNLPPVAVVSPQLQELTLPLTSALIDGSQSTDDTEIVSYHWEEINGPFIEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NVTVKPARRVNLPPVAVVSPQLQELTLPLTSALIDGSQSTDDTEIVSYHWEEINGPFIEE
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD KTSVDSPVLRLSNLDPGNYSFRLTVTDSDGATNSTTAALIVNNAVDYPPVANAGPNHTIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KTSVDSPVLRLSNLDPGNYSFRLTVTDSDGATNSTTAALIVNNAVDYPPVANAGPNHTIT
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD LPQNSITLNGNQSSDDHQIVLYEWSLGPGSEGKHVVMQGVQTPYLHLSAMQEGDYTFQLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPQNSITLNGNQSSDDHQIVLYEWSLGPGSEGKHVVMQGVQTPYLHLSAMQEGDYTFQLK
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD VTDSSRQQSTAVVTVIVQPENNRPPVAVAGPDKELIFPVESATLDGSSSSDDHGIVFYHW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTDSSRQQSTAVVTVIVQPENNRPPVAVAGPDKELIFPVESATLDGSSSSDDHGIVFYHW
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD EHVRGPSAVEMENIDKAIATVTGLQVGTYHFRLTVKDQQGLSSTSTLTVAVKKENNSPPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EHVRGPSAVEMENIDKAIATVTGLQVGTYHFRLTVKDQQGLSSTSTLTVAVKKENNSPPR
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD ARAGGRHVLVLPNNSITLDGSRSTDDQRIVSYLWIRDGQSPAAGDVIDGSDHSVALQLTN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ARAGGRHVLVLPNNSITLDGSRSTDDQRIVSYLWIRDGQSPAAGDVIDGSDHSVALQLTN
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KSD LVEGVYTFHLRVTDSQGASDTDTATVEVQPDPRKSGLVELTLQVGVGQLTEQRKDTLVRQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVEGVYTFHLRVTDSQGASDTDTATVEVQPDPRKSGLVELTLQVGVGQLTEQRKDTLVRQ
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KSD LAVLLNVLDSDIKVQKIRAHSDLSTVIVFYVQSRPPFKVLKAAEVARNLHMRLSKEKADF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAVLLNVLDSDIKVQKIRAHSDLSTVIVFYVQSRPPFKVLKAAEVARNLHMRLSKEKADF
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KSD LLFKVLRVDTAGCLLKCSGHGHCDPLTKRCICSHLWMENLIQRYIWDGESNCEWSIFYVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLFKVLRVDTAGCLLKCSGHGHCDPLTKRCICSHLWMENLIQRYIWDGESNCEWSIFYVT
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KSD VLAFTLIVLTGGFTWLCICCCKRQKRTKIRKKTKYTILDNMDEQERMELRPKYGIKHRST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLAFTLIVLTGGFTWLCICCCKRQKRTKIRKKTKYTILDNMDEQERMELRPKYGIKHRST
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070  
pF1KSD EHNSSLMVSESEFDSDQDTIFSREKMERGNPKVSMNGSIRNGASFSYCSKDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EHNSSLMVSESEFDSDQDTIFSREKMERGNPKVSMNGSIRNGASFSYCSKDR
             1030      1040      1050      1060      1070  

>>NP_055624 (OMIM: 600202,609269) dyslexia-associated pr  (1072 aa)
 initn: 7106 init1: 7106 opt: 7106  Z-score: 4737.3  bits: 888.3 E(85289):    0
Smith-Waterman score: 7106; 99.8% identity (99.9% similar) in 1072 aa overlap (1-1072:1-1072)

               10        20        30        40        50        60
pF1KSD MAPPTGVLSSLLLLVTIAGCARKQCSEGRTYSNAVISPNLETTRIMRVSHTFPVVDCTAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MAPPTGVLSSLLLLVTIAGCARKQCSEGRTYSNAVISPNLETTRIMRVSHTFPVVDCTAA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD CCDLSSCDLAWWFEGRCYLVSCPHKENCEPKKMGPIRSYLTFVLRPVQRPAQLLDYGDMM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 CCDLSSCDLAWWFEGRCYLVSCPHKENCEPKKMGPIRSYLTFVLRPVQRPAQLLDYGDMM
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD LNRGSPSGIWGDSPEDIRKDLPFLGKDWGLEEMSEYADDYRELEKDLLQPSGKQEPRGSA
       ::::::::::::::::::::: ::::::::::::::.:::::::::::::::::::::::
NP_055 LNRGSPSGIWGDSPEDIRKDLTFLGKDWGLEEMSEYSDDYRELEKDLLQPSGKQEPRGSA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD EYTDWGLLPGSEGAFNSSVGDSPAVPAETQQDPELHYLNESASTPAPKLPERSVLLPLPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EYTDWGLLPGSEGAFNSSVGDSPAVPAETQQDPELHYLNESASTPAPKLPERSVLLPLPT
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD TPSSGEVLEKEKASQLQEQSSNSSGKEVLMPSHSLPPASLELSSVTVEKSPVLTVTPGST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TPSSGEVLEKEKASQLQEQSSNSSGKEVLMPSHSLPPASLELSSVTVEKSPVLTVTPGST
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD EHSIPTPPTSAAPSESTPSELPISPTTAPRTVKELTVSAGDNLIITLPDNEVELKAFVAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EHSIPTPPTSAAPSESTPSELPISPTTAPRTVKELTVSAGDNLIITLPDNEVELKAFVAP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD APPVETTYNYEWNLISHPTDYQGEIKQGHKQTLNLSQLSVGLYVFKVTVSSENAFGEGFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 APPVETTYNYEWNLISHPTDYQGEIKQGHKQTLNLSQLSVGLYVFKVTVSSENAFGEGFV
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD NVTVKPARRVNLPPVAVVSPQLQELTLPLTSALIDGSQSTDDTEIVSYHWEEINGPFIEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 NVTVKPARRVNLPPVAVVSPQLQELTLPLTSALIDGSQSTDDTEIVSYHWEEINGPFIEE
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD KTSVDSPVLRLSNLDPGNYSFRLTVTDSDGATNSTTAALIVNNAVDYPPVANAGPNHTIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KTSVDSPVLRLSNLDPGNYSFRLTVTDSDGATNSTTAALIVNNAVDYPPVANAGPNHTIT
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD LPQNSITLNGNQSSDDHQIVLYEWSLGPGSEGKHVVMQGVQTPYLHLSAMQEGDYTFQLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LPQNSITLNGNQSSDDHQIVLYEWSLGPGSEGKHVVMQGVQTPYLHLSAMQEGDYTFQLK
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD VTDSSRQQSTAVVTVIVQPENNRPPVAVAGPDKELIFPVESATLDGSSSSDDHGIVFYHW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VTDSSRQQSTAVVTVIVQPENNRPPVAVAGPDKELIFPVESATLDGSSSSDDHGIVFYHW
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD EHVRGPSAVEMENIDKAIATVTGLQVGTYHFRLTVKDQQGLSSTSTLTVAVKKENNSPPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EHVRGPSAVEMENIDKAIATVTGLQVGTYHFRLTVKDQQGLSSTSTLTVAVKKENNSPPR
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD ARAGGRHVLVLPNNSITLDGSRSTDDQRIVSYLWIRDGQSPAAGDVIDGSDHSVALQLTN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ARAGGRHVLVLPNNSITLDGSRSTDDQRIVSYLWIRDGQSPAAGDVIDGSDHSVALQLTN
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KSD LVEGVYTFHLRVTDSQGASDTDTATVEVQPDPRKSGLVELTLQVGVGQLTEQRKDTLVRQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LVEGVYTFHLRVTDSQGASDTDTATVEVQPDPRKSGLVELTLQVGVGQLTEQRKDTLVRQ
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KSD LAVLLNVLDSDIKVQKIRAHSDLSTVIVFYVQSRPPFKVLKAAEVARNLHMRLSKEKADF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LAVLLNVLDSDIKVQKIRAHSDLSTVIVFYVQSRPPFKVLKAAEVARNLHMRLSKEKADF
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KSD LLFKVLRVDTAGCLLKCSGHGHCDPLTKRCICSHLWMENLIQRYIWDGESNCEWSIFYVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LLFKVLRVDTAGCLLKCSGHGHCDPLTKRCICSHLWMENLIQRYIWDGESNCEWSIFYVT
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KSD VLAFTLIVLTGGFTWLCICCCKRQKRTKIRKKTKYTILDNMDEQERMELRPKYGIKHRST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VLAFTLIVLTGGFTWLCICCCKRQKRTKIRKKTKYTILDNMDEQERMELRPKYGIKHRST
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070  
pF1KSD EHNSSLMVSESEFDSDQDTIFSREKMERGNPKVSMNGSIRNGASFSYCSKDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EHNSSLMVSESEFDSDQDTIFSREKMERGNPKVSMNGSIRNGASFSYCSKDR
             1030      1040      1050      1060      1070  

>>NP_001161846 (OMIM: 600202,609269) dyslexia-associated  (1063 aa)
 initn: 6993 init1: 6993 opt: 6993  Z-score: 4662.2  bits: 874.4 E(85289):    0
Smith-Waterman score: 6993; 99.8% identity (99.9% similar) in 1053 aa overlap (20-1072:11-1063)

               10        20        30        40        50        60
pF1KSD MAPPTGVLSSLLLLVTIAGCARKQCSEGRTYSNAVISPNLETTRIMRVSHTFPVVDCTAA
                          :::::::::::::::::::::::::::::::::::::::::
NP_001          MTRLGWPSPCCARKQCSEGRTYSNAVISPNLETTRIMRVSHTFPVVDCTAA
                        10        20        30        40        50 

               70        80        90       100       110       120
pF1KSD CCDLSSCDLAWWFEGRCYLVSCPHKENCEPKKMGPIRSYLTFVLRPVQRPAQLLDYGDMM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CCDLSSCDLAWWFEGRCYLVSCPHKENCEPKKMGPIRSYLTFVLRPVQRPAQLLDYGDMM
              60        70        80        90       100       110 

              130       140       150       160       170       180
pF1KSD LNRGSPSGIWGDSPEDIRKDLPFLGKDWGLEEMSEYADDYRELEKDLLQPSGKQEPRGSA
       ::::::::::::::::::::: ::::::::::::::.:::::::::::::::::::::::
NP_001 LNRGSPSGIWGDSPEDIRKDLTFLGKDWGLEEMSEYSDDYRELEKDLLQPSGKQEPRGSA
             120       130       140       150       160       170 

              190       200       210       220       230       240
pF1KSD EYTDWGLLPGSEGAFNSSVGDSPAVPAETQQDPELHYLNESASTPAPKLPERSVLLPLPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EYTDWGLLPGSEGAFNSSVGDSPAVPAETQQDPELHYLNESASTPAPKLPERSVLLPLPT
             180       190       200       210       220       230 

              250       260       270       280       290       300
pF1KSD TPSSGEVLEKEKASQLQEQSSNSSGKEVLMPSHSLPPASLELSSVTVEKSPVLTVTPGST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPSSGEVLEKEKASQLQEQSSNSSGKEVLMPSHSLPPASLELSSVTVEKSPVLTVTPGST
             240       250       260       270       280       290 

              310       320       330       340       350       360
pF1KSD EHSIPTPPTSAAPSESTPSELPISPTTAPRTVKELTVSAGDNLIITLPDNEVELKAFVAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EHSIPTPPTSAAPSESTPSELPISPTTAPRTVKELTVSAGDNLIITLPDNEVELKAFVAP
             300       310       320       330       340       350 

              370       380       390       400       410       420
pF1KSD APPVETTYNYEWNLISHPTDYQGEIKQGHKQTLNLSQLSVGLYVFKVTVSSENAFGEGFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APPVETTYNYEWNLISHPTDYQGEIKQGHKQTLNLSQLSVGLYVFKVTVSSENAFGEGFV
             360       370       380       390       400       410 

              430       440       450       460       470       480
pF1KSD NVTVKPARRVNLPPVAVVSPQLQELTLPLTSALIDGSQSTDDTEIVSYHWEEINGPFIEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NVTVKPARRVNLPPVAVVSPQLQELTLPLTSALIDGSQSTDDTEIVSYHWEEINGPFIEE
             420       430       440       450       460       470 

              490       500       510       520       530       540
pF1KSD KTSVDSPVLRLSNLDPGNYSFRLTVTDSDGATNSTTAALIVNNAVDYPPVANAGPNHTIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KTSVDSPVLRLSNLDPGNYSFRLTVTDSDGATNSTTAALIVNNAVDYPPVANAGPNHTIT
             480       490       500       510       520       530 

              550       560       570       580       590       600
pF1KSD LPQNSITLNGNQSSDDHQIVLYEWSLGPGSEGKHVVMQGVQTPYLHLSAMQEGDYTFQLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPQNSITLNGNQSSDDHQIVLYEWSLGPGSEGKHVVMQGVQTPYLHLSAMQEGDYTFQLK
             540       550       560       570       580       590 

              610       620       630       640       650       660
pF1KSD VTDSSRQQSTAVVTVIVQPENNRPPVAVAGPDKELIFPVESATLDGSSSSDDHGIVFYHW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTDSSRQQSTAVVTVIVQPENNRPPVAVAGPDKELIFPVESATLDGSSSSDDHGIVFYHW
             600       610       620       630       640       650 

              670       680       690       700       710       720
pF1KSD EHVRGPSAVEMENIDKAIATVTGLQVGTYHFRLTVKDQQGLSSTSTLTVAVKKENNSPPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EHVRGPSAVEMENIDKAIATVTGLQVGTYHFRLTVKDQQGLSSTSTLTVAVKKENNSPPR
             660       670       680       690       700       710 

              730       740       750       760       770       780
pF1KSD ARAGGRHVLVLPNNSITLDGSRSTDDQRIVSYLWIRDGQSPAAGDVIDGSDHSVALQLTN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARAGGRHVLVLPNNSITLDGSRSTDDQRIVSYLWIRDGQSPAAGDVIDGSDHSVALQLTN
             720       730       740       750       760       770 

              790       800       810       820       830       840
pF1KSD LVEGVYTFHLRVTDSQGASDTDTATVEVQPDPRKSGLVELTLQVGVGQLTEQRKDTLVRQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVEGVYTFHLRVTDSQGASDTDTATVEVQPDPRKSGLVELTLQVGVGQLTEQRKDTLVRQ
             780       790       800       810       820       830 

              850       860       870       880       890       900
pF1KSD LAVLLNVLDSDIKVQKIRAHSDLSTVIVFYVQSRPPFKVLKAAEVARNLHMRLSKEKADF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAVLLNVLDSDIKVQKIRAHSDLSTVIVFYVQSRPPFKVLKAAEVARNLHMRLSKEKADF
             840       850       860       870       880       890 

              910       920       930       940       950       960
pF1KSD LLFKVLRVDTAGCLLKCSGHGHCDPLTKRCICSHLWMENLIQRYIWDGESNCEWSIFYVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLFKVLRVDTAGCLLKCSGHGHCDPLTKRCICSHLWMENLIQRYIWDGESNCEWSIFYVT
             900       910       920       930       940       950 

              970       980       990      1000      1010      1020
pF1KSD VLAFTLIVLTGGFTWLCICCCKRQKRTKIRKKTKYTILDNMDEQERMELRPKYGIKHRST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLAFTLIVLTGGFTWLCICCCKRQKRTKIRKKTKYTILDNMDEQERMELRPKYGIKHRST
             960       970       980       990      1000      1010 

             1030      1040      1050      1060      1070  
pF1KSD EHNSSLMVSESEFDSDQDTIFSREKMERGNPKVSMNGSIRNGASFSYCSKDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EHNSSLMVSESEFDSDQDTIFSREKMERGNPKVSMNGSIRNGASFSYCSKDR
            1020      1030      1040      1050      1060   

>>XP_016867030 (OMIM: 600202,609269) PREDICTED: dyslexia  (1063 aa)
 initn: 6993 init1: 6993 opt: 6993  Z-score: 4662.2  bits: 874.4 E(85289):    0
Smith-Waterman score: 6993; 99.8% identity (99.9% similar) in 1053 aa overlap (20-1072:11-1063)

               10        20        30        40        50        60
pF1KSD MAPPTGVLSSLLLLVTIAGCARKQCSEGRTYSNAVISPNLETTRIMRVSHTFPVVDCTAA
                          :::::::::::::::::::::::::::::::::::::::::
XP_016          MTRLGWPSPCCARKQCSEGRTYSNAVISPNLETTRIMRVSHTFPVVDCTAA
                        10        20        30        40        50 

               70        80        90       100       110       120
pF1KSD CCDLSSCDLAWWFEGRCYLVSCPHKENCEPKKMGPIRSYLTFVLRPVQRPAQLLDYGDMM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CCDLSSCDLAWWFEGRCYLVSCPHKENCEPKKMGPIRSYLTFVLRPVQRPAQLLDYGDMM
              60        70        80        90       100       110 

              130       140       150       160       170       180
pF1KSD LNRGSPSGIWGDSPEDIRKDLPFLGKDWGLEEMSEYADDYRELEKDLLQPSGKQEPRGSA
       ::::::::::::::::::::: ::::::::::::::.:::::::::::::::::::::::
XP_016 LNRGSPSGIWGDSPEDIRKDLTFLGKDWGLEEMSEYSDDYRELEKDLLQPSGKQEPRGSA
             120       130       140       150       160       170 

              190       200       210       220       230       240
pF1KSD EYTDWGLLPGSEGAFNSSVGDSPAVPAETQQDPELHYLNESASTPAPKLPERSVLLPLPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EYTDWGLLPGSEGAFNSSVGDSPAVPAETQQDPELHYLNESASTPAPKLPERSVLLPLPT
             180       190       200       210       220       230 

              250       260       270       280       290       300
pF1KSD TPSSGEVLEKEKASQLQEQSSNSSGKEVLMPSHSLPPASLELSSVTVEKSPVLTVTPGST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPSSGEVLEKEKASQLQEQSSNSSGKEVLMPSHSLPPASLELSSVTVEKSPVLTVTPGST
             240       250       260       270       280       290 

              310       320       330       340       350       360
pF1KSD EHSIPTPPTSAAPSESTPSELPISPTTAPRTVKELTVSAGDNLIITLPDNEVELKAFVAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EHSIPTPPTSAAPSESTPSELPISPTTAPRTVKELTVSAGDNLIITLPDNEVELKAFVAP
             300       310       320       330       340       350 

              370       380       390       400       410       420
pF1KSD APPVETTYNYEWNLISHPTDYQGEIKQGHKQTLNLSQLSVGLYVFKVTVSSENAFGEGFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APPVETTYNYEWNLISHPTDYQGEIKQGHKQTLNLSQLSVGLYVFKVTVSSENAFGEGFV
             360       370       380       390       400       410 

              430       440       450       460       470       480
pF1KSD NVTVKPARRVNLPPVAVVSPQLQELTLPLTSALIDGSQSTDDTEIVSYHWEEINGPFIEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NVTVKPARRVNLPPVAVVSPQLQELTLPLTSALIDGSQSTDDTEIVSYHWEEINGPFIEE
             420       430       440       450       460       470 

              490       500       510       520       530       540
pF1KSD KTSVDSPVLRLSNLDPGNYSFRLTVTDSDGATNSTTAALIVNNAVDYPPVANAGPNHTIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTSVDSPVLRLSNLDPGNYSFRLTVTDSDGATNSTTAALIVNNAVDYPPVANAGPNHTIT
             480       490       500       510       520       530 

              550       560       570       580       590       600
pF1KSD LPQNSITLNGNQSSDDHQIVLYEWSLGPGSEGKHVVMQGVQTPYLHLSAMQEGDYTFQLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPQNSITLNGNQSSDDHQIVLYEWSLGPGSEGKHVVMQGVQTPYLHLSAMQEGDYTFQLK
             540       550       560       570       580       590 

              610       620       630       640       650       660
pF1KSD VTDSSRQQSTAVVTVIVQPENNRPPVAVAGPDKELIFPVESATLDGSSSSDDHGIVFYHW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTDSSRQQSTAVVTVIVQPENNRPPVAVAGPDKELIFPVESATLDGSSSSDDHGIVFYHW
             600       610       620       630       640       650 

              670       680       690       700       710       720
pF1KSD EHVRGPSAVEMENIDKAIATVTGLQVGTYHFRLTVKDQQGLSSTSTLTVAVKKENNSPPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EHVRGPSAVEMENIDKAIATVTGLQVGTYHFRLTVKDQQGLSSTSTLTVAVKKENNSPPR
             660       670       680       690       700       710 

              730       740       750       760       770       780
pF1KSD ARAGGRHVLVLPNNSITLDGSRSTDDQRIVSYLWIRDGQSPAAGDVIDGSDHSVALQLTN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARAGGRHVLVLPNNSITLDGSRSTDDQRIVSYLWIRDGQSPAAGDVIDGSDHSVALQLTN
             720       730       740       750       760       770 

              790       800       810       820       830       840
pF1KSD LVEGVYTFHLRVTDSQGASDTDTATVEVQPDPRKSGLVELTLQVGVGQLTEQRKDTLVRQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVEGVYTFHLRVTDSQGASDTDTATVEVQPDPRKSGLVELTLQVGVGQLTEQRKDTLVRQ
             780       790       800       810       820       830 

              850       860       870       880       890       900
pF1KSD LAVLLNVLDSDIKVQKIRAHSDLSTVIVFYVQSRPPFKVLKAAEVARNLHMRLSKEKADF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAVLLNVLDSDIKVQKIRAHSDLSTVIVFYVQSRPPFKVLKAAEVARNLHMRLSKEKADF
             840       850       860       870       880       890 

              910       920       930       940       950       960
pF1KSD LLFKVLRVDTAGCLLKCSGHGHCDPLTKRCICSHLWMENLIQRYIWDGESNCEWSIFYVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLFKVLRVDTAGCLLKCSGHGHCDPLTKRCICSHLWMENLIQRYIWDGESNCEWSIFYVT
             900       910       920       930       940       950 

              970       980       990      1000      1010      1020
pF1KSD VLAFTLIVLTGGFTWLCICCCKRQKRTKIRKKTKYTILDNMDEQERMELRPKYGIKHRST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLAFTLIVLTGGFTWLCICCCKRQKRTKIRKKTKYTILDNMDEQERMELRPKYGIKHRST
             960       970       980       990      1000      1010 

             1030      1040      1050      1060      1070  
pF1KSD EHNSSLMVSESEFDSDQDTIFSREKMERGNPKVSMNGSIRNGASFSYCSKDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EHNSSLMVSESEFDSDQDTIFSREKMERGNPKVSMNGSIRNGASFSYCSKDR
            1020      1030      1040      1050      1060   

>>XP_016867034 (OMIM: 600202,609269) PREDICTED: dyslexia  (1027 aa)
 initn: 6821 init1: 6821 opt: 6821  Z-score: 4548.1  bits: 853.2 E(85289):    0
Smith-Waterman score: 6821; 99.8% identity (99.9% similar) in 1027 aa overlap (46-1072:1-1027)

          20        30        40        50        60        70     
pF1KSD TIAGCARKQCSEGRTYSNAVISPNLETTRIMRVSHTFPVVDCTAACCDLSSCDLAWWFEG
                                     ::::::::::::::::::::::::::::::
XP_016                               MRVSHTFPVVDCTAACCDLSSCDLAWWFEG
                                             10        20        30

          80        90       100       110       120       130     
pF1KSD RCYLVSCPHKENCEPKKMGPIRSYLTFVLRPVQRPAQLLDYGDMMLNRGSPSGIWGDSPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RCYLVSCPHKENCEPKKMGPIRSYLTFVLRPVQRPAQLLDYGDMMLNRGSPSGIWGDSPE
               40        50        60        70        80        90

         140       150       160       170       180       190     
pF1KSD DIRKDLPFLGKDWGLEEMSEYADDYRELEKDLLQPSGKQEPRGSAEYTDWGLLPGSEGAF
       :::::: ::::::::::::::.::::::::::::::::::::::::::::::::::::::
XP_016 DIRKDLTFLGKDWGLEEMSEYSDDYRELEKDLLQPSGKQEPRGSAEYTDWGLLPGSEGAF
              100       110       120       130       140       150

         200       210       220       230       240       250     
pF1KSD NSSVGDSPAVPAETQQDPELHYLNESASTPAPKLPERSVLLPLPTTPSSGEVLEKEKASQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSSVGDSPAVPAETQQDPELHYLNESASTPAPKLPERSVLLPLPTTPSSGEVLEKEKASQ
              160       170       180       190       200       210

         260       270       280       290       300       310     
pF1KSD LQEQSSNSSGKEVLMPSHSLPPASLELSSVTVEKSPVLTVTPGSTEHSIPTPPTSAAPSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQEQSSNSSGKEVLMPSHSLPPASLELSSVTVEKSPVLTVTPGSTEHSIPTPPTSAAPSE
              220       230       240       250       260       270

         320       330       340       350       360       370     
pF1KSD STPSELPISPTTAPRTVKELTVSAGDNLIITLPDNEVELKAFVAPAPPVETTYNYEWNLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STPSELPISPTTAPRTVKELTVSAGDNLIITLPDNEVELKAFVAPAPPVETTYNYEWNLI
              280       290       300       310       320       330

         380       390       400       410       420       430     
pF1KSD SHPTDYQGEIKQGHKQTLNLSQLSVGLYVFKVTVSSENAFGEGFVNVTVKPARRVNLPPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SHPTDYQGEIKQGHKQTLNLSQLSVGLYVFKVTVSSENAFGEGFVNVTVKPARRVNLPPV
              340       350       360       370       380       390

         440       450       460       470       480       490     
pF1KSD AVVSPQLQELTLPLTSALIDGSQSTDDTEIVSYHWEEINGPFIEEKTSVDSPVLRLSNLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVVSPQLQELTLPLTSALIDGSQSTDDTEIVSYHWEEINGPFIEEKTSVDSPVLRLSNLD
              400       410       420       430       440       450

         500       510       520       530       540       550     
pF1KSD PGNYSFRLTVTDSDGATNSTTAALIVNNAVDYPPVANAGPNHTITLPQNSITLNGNQSSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGNYSFRLTVTDSDGATNSTTAALIVNNAVDYPPVANAGPNHTITLPQNSITLNGNQSSD
              460       470       480       490       500       510

         560       570       580       590       600       610     
pF1KSD DHQIVLYEWSLGPGSEGKHVVMQGVQTPYLHLSAMQEGDYTFQLKVTDSSRQQSTAVVTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DHQIVLYEWSLGPGSEGKHVVMQGVQTPYLHLSAMQEGDYTFQLKVTDSSRQQSTAVVTV
              520       530       540       550       560       570

         620       630       640       650       660       670     
pF1KSD IVQPENNRPPVAVAGPDKELIFPVESATLDGSSSSDDHGIVFYHWEHVRGPSAVEMENID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IVQPENNRPPVAVAGPDKELIFPVESATLDGSSSSDDHGIVFYHWEHVRGPSAVEMENID
              580       590       600       610       620       630

         680       690       700       710       720       730     
pF1KSD KAIATVTGLQVGTYHFRLTVKDQQGLSSTSTLTVAVKKENNSPPRARAGGRHVLVLPNNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KAIATVTGLQVGTYHFRLTVKDQQGLSSTSTLTVAVKKENNSPPRARAGGRHVLVLPNNS
              640       650       660       670       680       690

         740       750       760       770       780       790     
pF1KSD ITLDGSRSTDDQRIVSYLWIRDGQSPAAGDVIDGSDHSVALQLTNLVEGVYTFHLRVTDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ITLDGSRSTDDQRIVSYLWIRDGQSPAAGDVIDGSDHSVALQLTNLVEGVYTFHLRVTDS
              700       710       720       730       740       750

         800       810       820       830       840       850     
pF1KSD QGASDTDTATVEVQPDPRKSGLVELTLQVGVGQLTEQRKDTLVRQLAVLLNVLDSDIKVQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QGASDTDTATVEVQPDPRKSGLVELTLQVGVGQLTEQRKDTLVRQLAVLLNVLDSDIKVQ
              760       770       780       790       800       810

         860       870       880       890       900       910     
pF1KSD KIRAHSDLSTVIVFYVQSRPPFKVLKAAEVARNLHMRLSKEKADFLLFKVLRVDTAGCLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KIRAHSDLSTVIVFYVQSRPPFKVLKAAEVARNLHMRLSKEKADFLLFKVLRVDTAGCLL
              820       830       840       850       860       870

         920       930       940       950       960       970     
pF1KSD KCSGHGHCDPLTKRCICSHLWMENLIQRYIWDGESNCEWSIFYVTVLAFTLIVLTGGFTW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KCSGHGHCDPLTKRCICSHLWMENLIQRYIWDGESNCEWSIFYVTVLAFTLIVLTGGFTW
              880       890       900       910       920       930

         980       990      1000      1010      1020      1030     
pF1KSD LCICCCKRQKRTKIRKKTKYTILDNMDEQERMELRPKYGIKHRSTEHNSSLMVSESEFDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LCICCCKRQKRTKIRKKTKYTILDNMDEQERMELRPKYGIKHRSTEHNSSLMVSESEFDS
              940       950       960       970       980       990

        1040      1050      1060      1070  
pF1KSD DQDTIFSREKMERGNPKVSMNGSIRNGASFSYCSKDR
       :::::::::::::::::::::::::::::::::::::
XP_016 DQDTIFSREKMERGNPKVSMNGSIRNGASFSYCSKDR
             1000      1010      1020       

>>XP_011513328 (OMIM: 600202,609269) PREDICTED: dyslexia  (1027 aa)
 initn: 6821 init1: 6821 opt: 6821  Z-score: 4548.1  bits: 853.2 E(85289):    0
Smith-Waterman score: 6821; 99.8% identity (99.9% similar) in 1027 aa overlap (46-1072:1-1027)

          20        30        40        50        60        70     
pF1KSD TIAGCARKQCSEGRTYSNAVISPNLETTRIMRVSHTFPVVDCTAACCDLSSCDLAWWFEG
                                     ::::::::::::::::::::::::::::::
XP_011                               MRVSHTFPVVDCTAACCDLSSCDLAWWFEG
                                             10        20        30

          80        90       100       110       120       130     
pF1KSD RCYLVSCPHKENCEPKKMGPIRSYLTFVLRPVQRPAQLLDYGDMMLNRGSPSGIWGDSPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RCYLVSCPHKENCEPKKMGPIRSYLTFVLRPVQRPAQLLDYGDMMLNRGSPSGIWGDSPE
               40        50        60        70        80        90

         140       150       160       170       180       190     
pF1KSD DIRKDLPFLGKDWGLEEMSEYADDYRELEKDLLQPSGKQEPRGSAEYTDWGLLPGSEGAF
       :::::: ::::::::::::::.::::::::::::::::::::::::::::::::::::::
XP_011 DIRKDLTFLGKDWGLEEMSEYSDDYRELEKDLLQPSGKQEPRGSAEYTDWGLLPGSEGAF
              100       110       120       130       140       150

         200       210       220       230       240       250     
pF1KSD NSSVGDSPAVPAETQQDPELHYLNESASTPAPKLPERSVLLPLPTTPSSGEVLEKEKASQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSSVGDSPAVPAETQQDPELHYLNESASTPAPKLPERSVLLPLPTTPSSGEVLEKEKASQ
              160       170       180       190       200       210

         260       270       280       290       300       310     
pF1KSD LQEQSSNSSGKEVLMPSHSLPPASLELSSVTVEKSPVLTVTPGSTEHSIPTPPTSAAPSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQEQSSNSSGKEVLMPSHSLPPASLELSSVTVEKSPVLTVTPGSTEHSIPTPPTSAAPSE
              220       230       240       250       260       270

         320       330       340       350       360       370     
pF1KSD STPSELPISPTTAPRTVKELTVSAGDNLIITLPDNEVELKAFVAPAPPVETTYNYEWNLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STPSELPISPTTAPRTVKELTVSAGDNLIITLPDNEVELKAFVAPAPPVETTYNYEWNLI
              280       290       300       310       320       330

         380       390       400       410       420       430     
pF1KSD SHPTDYQGEIKQGHKQTLNLSQLSVGLYVFKVTVSSENAFGEGFVNVTVKPARRVNLPPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SHPTDYQGEIKQGHKQTLNLSQLSVGLYVFKVTVSSENAFGEGFVNVTVKPARRVNLPPV
              340       350       360       370       380       390

         440       450       460       470       480       490     
pF1KSD AVVSPQLQELTLPLTSALIDGSQSTDDTEIVSYHWEEINGPFIEEKTSVDSPVLRLSNLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVVSPQLQELTLPLTSALIDGSQSTDDTEIVSYHWEEINGPFIEEKTSVDSPVLRLSNLD
              400       410       420       430       440       450

         500       510       520       530       540       550     
pF1KSD PGNYSFRLTVTDSDGATNSTTAALIVNNAVDYPPVANAGPNHTITLPQNSITLNGNQSSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGNYSFRLTVTDSDGATNSTTAALIVNNAVDYPPVANAGPNHTITLPQNSITLNGNQSSD
              460       470       480       490       500       510

         560       570       580       590       600       610     
pF1KSD DHQIVLYEWSLGPGSEGKHVVMQGVQTPYLHLSAMQEGDYTFQLKVTDSSRQQSTAVVTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DHQIVLYEWSLGPGSEGKHVVMQGVQTPYLHLSAMQEGDYTFQLKVTDSSRQQSTAVVTV
              520       530       540       550       560       570

         620       630       640       650       660       670     
pF1KSD IVQPENNRPPVAVAGPDKELIFPVESATLDGSSSSDDHGIVFYHWEHVRGPSAVEMENID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IVQPENNRPPVAVAGPDKELIFPVESATLDGSSSSDDHGIVFYHWEHVRGPSAVEMENID
              580       590       600       610       620       630

         680       690       700       710       720       730     
pF1KSD KAIATVTGLQVGTYHFRLTVKDQQGLSSTSTLTVAVKKENNSPPRARAGGRHVLVLPNNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAIATVTGLQVGTYHFRLTVKDQQGLSSTSTLTVAVKKENNSPPRARAGGRHVLVLPNNS
              640       650       660       670       680       690

         740       750       760       770       780       790     
pF1KSD ITLDGSRSTDDQRIVSYLWIRDGQSPAAGDVIDGSDHSVALQLTNLVEGVYTFHLRVTDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ITLDGSRSTDDQRIVSYLWIRDGQSPAAGDVIDGSDHSVALQLTNLVEGVYTFHLRVTDS
              700       710       720       730       740       750

         800       810       820       830       840       850     
pF1KSD QGASDTDTATVEVQPDPRKSGLVELTLQVGVGQLTEQRKDTLVRQLAVLLNVLDSDIKVQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QGASDTDTATVEVQPDPRKSGLVELTLQVGVGQLTEQRKDTLVRQLAVLLNVLDSDIKVQ
              760       770       780       790       800       810

         860       870       880       890       900       910     
pF1KSD KIRAHSDLSTVIVFYVQSRPPFKVLKAAEVARNLHMRLSKEKADFLLFKVLRVDTAGCLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KIRAHSDLSTVIVFYVQSRPPFKVLKAAEVARNLHMRLSKEKADFLLFKVLRVDTAGCLL
              820       830       840       850       860       870

         920       930       940       950       960       970     
pF1KSD KCSGHGHCDPLTKRCICSHLWMENLIQRYIWDGESNCEWSIFYVTVLAFTLIVLTGGFTW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KCSGHGHCDPLTKRCICSHLWMENLIQRYIWDGESNCEWSIFYVTVLAFTLIVLTGGFTW
              880       890       900       910       920       930

         980       990      1000      1010      1020      1030     
pF1KSD LCICCCKRQKRTKIRKKTKYTILDNMDEQERMELRPKYGIKHRSTEHNSSLMVSESEFDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LCICCCKRQKRTKIRKKTKYTILDNMDEQERMELRPKYGIKHRSTEHNSSLMVSESEFDS
              940       950       960       970       980       990

        1040      1050      1060      1070  
pF1KSD DQDTIFSREKMERGNPKVSMNGSIRNGASFSYCSKDR
       :::::::::::::::::::::::::::::::::::::
XP_011 DQDTIFSREKMERGNPKVSMNGSIRNGASFSYCSKDR
             1000      1010      1020       

>>NP_001161848 (OMIM: 600202,609269) dyslexia-associated  (1027 aa)
 initn: 6821 init1: 6821 opt: 6821  Z-score: 4548.1  bits: 853.2 E(85289):    0
Smith-Waterman score: 6821; 99.8% identity (99.9% similar) in 1027 aa overlap (46-1072:1-1027)

          20        30        40        50        60        70     
pF1KSD TIAGCARKQCSEGRTYSNAVISPNLETTRIMRVSHTFPVVDCTAACCDLSSCDLAWWFEG
                                     ::::::::::::::::::::::::::::::
NP_001                               MRVSHTFPVVDCTAACCDLSSCDLAWWFEG
                                             10        20        30

          80        90       100       110       120       130     
pF1KSD RCYLVSCPHKENCEPKKMGPIRSYLTFVLRPVQRPAQLLDYGDMMLNRGSPSGIWGDSPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RCYLVSCPHKENCEPKKMGPIRSYLTFVLRPVQRPAQLLDYGDMMLNRGSPSGIWGDSPE
               40        50        60        70        80        90

         140       150       160       170       180       190     
pF1KSD DIRKDLPFLGKDWGLEEMSEYADDYRELEKDLLQPSGKQEPRGSAEYTDWGLLPGSEGAF
       :::::: ::::::::::::::.::::::::::::::::::::::::::::::::::::::
NP_001 DIRKDLTFLGKDWGLEEMSEYSDDYRELEKDLLQPSGKQEPRGSAEYTDWGLLPGSEGAF
              100       110       120       130       140       150

         200       210       220       230       240       250     
pF1KSD NSSVGDSPAVPAETQQDPELHYLNESASTPAPKLPERSVLLPLPTTPSSGEVLEKEKASQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NSSVGDSPAVPAETQQDPELHYLNESASTPAPKLPERSVLLPLPTTPSSGEVLEKEKASQ
              160       170       180       190       200       210

         260       270       280       290       300       310     
pF1KSD LQEQSSNSSGKEVLMPSHSLPPASLELSSVTVEKSPVLTVTPGSTEHSIPTPPTSAAPSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQEQSSNSSGKEVLMPSHSLPPASLELSSVTVEKSPVLTVTPGSTEHSIPTPPTSAAPSE
              220       230       240       250       260       270

         320       330       340       350       360       370     
pF1KSD STPSELPISPTTAPRTVKELTVSAGDNLIITLPDNEVELKAFVAPAPPVETTYNYEWNLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STPSELPISPTTAPRTVKELTVSAGDNLIITLPDNEVELKAFVAPAPPVETTYNYEWNLI
              280       290       300       310       320       330

         380       390       400       410       420       430     
pF1KSD SHPTDYQGEIKQGHKQTLNLSQLSVGLYVFKVTVSSENAFGEGFVNVTVKPARRVNLPPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SHPTDYQGEIKQGHKQTLNLSQLSVGLYVFKVTVSSENAFGEGFVNVTVKPARRVNLPPV
              340       350       360       370       380       390

         440       450       460       470       480       490     
pF1KSD AVVSPQLQELTLPLTSALIDGSQSTDDTEIVSYHWEEINGPFIEEKTSVDSPVLRLSNLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVVSPQLQELTLPLTSALIDGSQSTDDTEIVSYHWEEINGPFIEEKTSVDSPVLRLSNLD
              400       410       420       430       440       450

         500       510       520       530       540       550     
pF1KSD PGNYSFRLTVTDSDGATNSTTAALIVNNAVDYPPVANAGPNHTITLPQNSITLNGNQSSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGNYSFRLTVTDSDGATNSTTAALIVNNAVDYPPVANAGPNHTITLPQNSITLNGNQSSD
              460       470       480       490       500       510

         560       570       580       590       600       610     
pF1KSD DHQIVLYEWSLGPGSEGKHVVMQGVQTPYLHLSAMQEGDYTFQLKVTDSSRQQSTAVVTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DHQIVLYEWSLGPGSEGKHVVMQGVQTPYLHLSAMQEGDYTFQLKVTDSSRQQSTAVVTV
              520       530       540       550       560       570

         620       630       640       650       660       670     
pF1KSD IVQPENNRPPVAVAGPDKELIFPVESATLDGSSSSDDHGIVFYHWEHVRGPSAVEMENID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IVQPENNRPPVAVAGPDKELIFPVESATLDGSSSSDDHGIVFYHWEHVRGPSAVEMENID
              580       590       600       610       620       630

         680       690       700       710       720       730     
pF1KSD KAIATVTGLQVGTYHFRLTVKDQQGLSSTSTLTVAVKKENNSPPRARAGGRHVLVLPNNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KAIATVTGLQVGTYHFRLTVKDQQGLSSTSTLTVAVKKENNSPPRARAGGRHVLVLPNNS
              640       650       660       670       680       690

         740       750       760       770       780       790     
pF1KSD ITLDGSRSTDDQRIVSYLWIRDGQSPAAGDVIDGSDHSVALQLTNLVEGVYTFHLRVTDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ITLDGSRSTDDQRIVSYLWIRDGQSPAAGDVIDGSDHSVALQLTNLVEGVYTFHLRVTDS
              700       710       720       730       740       750

         800       810       820       830       840       850     
pF1KSD QGASDTDTATVEVQPDPRKSGLVELTLQVGVGQLTEQRKDTLVRQLAVLLNVLDSDIKVQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QGASDTDTATVEVQPDPRKSGLVELTLQVGVGQLTEQRKDTLVRQLAVLLNVLDSDIKVQ
              760       770       780       790       800       810

         860       870       880       890       900       910     
pF1KSD KIRAHSDLSTVIVFYVQSRPPFKVLKAAEVARNLHMRLSKEKADFLLFKVLRVDTAGCLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KIRAHSDLSTVIVFYVQSRPPFKVLKAAEVARNLHMRLSKEKADFLLFKVLRVDTAGCLL
              820       830       840       850       860       870

         920       930       940       950       960       970     
pF1KSD KCSGHGHCDPLTKRCICSHLWMENLIQRYIWDGESNCEWSIFYVTVLAFTLIVLTGGFTW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KCSGHGHCDPLTKRCICSHLWMENLIQRYIWDGESNCEWSIFYVTVLAFTLIVLTGGFTW
              880       890       900       910       920       930

         980       990      1000      1010      1020      1030     
pF1KSD LCICCCKRQKRTKIRKKTKYTILDNMDEQERMELRPKYGIKHRSTEHNSSLMVSESEFDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LCICCCKRQKRTKIRKKTKYTILDNMDEQERMELRPKYGIKHRSTEHNSSLMVSESEFDS
              940       950       960       970       980       990

        1040      1050      1060      1070  
pF1KSD DQDTIFSREKMERGNPKVSMNGSIRNGASFSYCSKDR
       :::::::::::::::::::::::::::::::::::::
NP_001 DQDTIFSREKMERGNPKVSMNGSIRNGASFSYCSKDR
             1000      1010      1020       

>>XP_016867031 (OMIM: 600202,609269) PREDICTED: dyslexia  (1047 aa)
 initn: 6717 init1: 6717 opt: 6720  Z-score: 4480.8  bits: 840.8 E(85289):    0
Smith-Waterman score: 6720; 98.9% identity (99.5% similar) in 1024 aa overlap (1-1024:1-1024)

               10        20        30        40        50        60
pF1KSD MAPPTGVLSSLLLLVTIAGCARKQCSEGRTYSNAVISPNLETTRIMRVSHTFPVVDCTAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAPPTGVLSSLLLLVTIAGCARKQCSEGRTYSNAVISPNLETTRIMRVSHTFPVVDCTAA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD CCDLSSCDLAWWFEGRCYLVSCPHKENCEPKKMGPIRSYLTFVLRPVQRPAQLLDYGDMM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CCDLSSCDLAWWFEGRCYLVSCPHKENCEPKKMGPIRSYLTFVLRPVQRPAQLLDYGDMM
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD LNRGSPSGIWGDSPEDIRKDLPFLGKDWGLEEMSEYADDYRELEKDLLQPSGKQEPRGSA
       ::::::::::::::::::::: ::::::::::::::.:::::::::::::::::::::::
XP_016 LNRGSPSGIWGDSPEDIRKDLTFLGKDWGLEEMSEYSDDYRELEKDLLQPSGKQEPRGSA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD EYTDWGLLPGSEGAFNSSVGDSPAVPAETQQDPELHYLNESASTPAPKLPERSVLLPLPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EYTDWGLLPGSEGAFNSSVGDSPAVPAETQQDPELHYLNESASTPAPKLPERSVLLPLPT
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD TPSSGEVLEKEKASQLQEQSSNSSGKEVLMPSHSLPPASLELSSVTVEKSPVLTVTPGST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPSSGEVLEKEKASQLQEQSSNSSGKEVLMPSHSLPPASLELSSVTVEKSPVLTVTPGST
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD EHSIPTPPTSAAPSESTPSELPISPTTAPRTVKELTVSAGDNLIITLPDNEVELKAFVAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EHSIPTPPTSAAPSESTPSELPISPTTAPRTVKELTVSAGDNLIITLPDNEVELKAFVAP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD APPVETTYNYEWNLISHPTDYQGEIKQGHKQTLNLSQLSVGLYVFKVTVSSENAFGEGFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APPVETTYNYEWNLISHPTDYQGEIKQGHKQTLNLSQLSVGLYVFKVTVSSENAFGEGFV
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD NVTVKPARRVNLPPVAVVSPQLQELTLPLTSALIDGSQSTDDTEIVSYHWEEINGPFIEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NVTVKPARRVNLPPVAVVSPQLQELTLPLTSALIDGSQSTDDTEIVSYHWEEINGPFIEE
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD KTSVDSPVLRLSNLDPGNYSFRLTVTDSDGATNSTTAALIVNNAVDYPPVANAGPNHTIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTSVDSPVLRLSNLDPGNYSFRLTVTDSDGATNSTTAALIVNNAVDYPPVANAGPNHTIT
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD LPQNSITLNGNQSSDDHQIVLYEWSLGPGSEGKHVVMQGVQTPYLHLSAMQEGDYTFQLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPQNSITLNGNQSSDDHQIVLYEWSLGPGSEGKHVVMQGVQTPYLHLSAMQEGDYTFQLK
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD VTDSSRQQSTAVVTVIVQPENNRPPVAVAGPDKELIFPVESATLDGSSSSDDHGIVFYHW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTDSSRQQSTAVVTVIVQPENNRPPVAVAGPDKELIFPVESATLDGSSSSDDHGIVFYHW
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD EHVRGPSAVEMENIDKAIATVTGLQVGTYHFRLTVKDQQGLSSTSTLTVAVKKENNSPPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EHVRGPSAVEMENIDKAIATVTGLQVGTYHFRLTVKDQQGLSSTSTLTVAVKKENNSPPR
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD ARAGGRHVLVLPNNSITLDGSRSTDDQRIVSYLWIRDGQSPAAGDVIDGSDHSVALQLTN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARAGGRHVLVLPNNSITLDGSRSTDDQRIVSYLWIRDGQSPAAGDVIDGSDHSVALQLTN
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KSD LVEGVYTFHLRVTDSQGASDTDTATVEVQPDPRKSGLVELTLQVGVGQLTEQRKDTLVRQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVEGVYTFHLRVTDSQGASDTDTATVEVQPDPRKSGLVELTLQVGVGQLTEQRKDTLVRQ
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KSD LAVLLNVLDSDIKVQKIRAHSDLSTVIVFYVQSRPPFKVLKAAEVARNLHMRLSKEKADF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAVLLNVLDSDIKVQKIRAHSDLSTVIVFYVQSRPPFKVLKAAEVARNLHMRLSKEKADF
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KSD LLFKVLRVDTAGCLLKCSGHGHCDPLTKRCICSHLWMENLIQRYIWDGESNCEWSIFYVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLFKVLRVDTAGCLLKCSGHGHCDPLTKRCICSHLWMENLIQRYIWDGESNCEWSIFYVT
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KSD VLAFTLIVLTGGFTWLCICCCKRQKRTKIRKKTKYTILDNMDEQERMELRPKYGIKHRST
       :::::::::::::::::::::::::::::::::::::::::::::::::::::  . :. 
XP_016 VLAFTLIVLTGGFTWLCICCCKRQKRTKIRKKTKYTILDNMDEQERMELRPKYEEEIRTC
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070  
pF1KSD EHNSSLMVSESEFDSDQDTIFSREKMERGNPKVSMNGSIRNGASFSYCSKDR
       ...:                                                
XP_016 RETSGARRHRGKIMGGHGKKAAIYKPR                         
             1030      1040                                

>>XP_016867035 (OMIM: 600202,609269) PREDICTED: dyslexia  (986 aa)
 initn: 6738 init1: 6301 opt: 6301  Z-score: 4202.7  bits: 789.2 E(85289):    0
Smith-Waterman score: 6301; 99.6% identity (99.7% similar) in 956 aa overlap (1-956:1-956)

               10        20        30        40        50        60
pF1KSD MAPPTGVLSSLLLLVTIAGCARKQCSEGRTYSNAVISPNLETTRIMRVSHTFPVVDCTAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAPPTGVLSSLLLLVTIAGCARKQCSEGRTYSNAVISPNLETTRIMRVSHTFPVVDCTAA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD CCDLSSCDLAWWFEGRCYLVSCPHKENCEPKKMGPIRSYLTFVLRPVQRPAQLLDYGDMM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CCDLSSCDLAWWFEGRCYLVSCPHKENCEPKKMGPIRSYLTFVLRPVQRPAQLLDYGDMM
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD LNRGSPSGIWGDSPEDIRKDLPFLGKDWGLEEMSEYADDYRELEKDLLQPSGKQEPRGSA
       ::::::::::::::::::::: ::::::::::::::.:::::::::::::::::::::::
XP_016 LNRGSPSGIWGDSPEDIRKDLTFLGKDWGLEEMSEYSDDYRELEKDLLQPSGKQEPRGSA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD EYTDWGLLPGSEGAFNSSVGDSPAVPAETQQDPELHYLNESASTPAPKLPERSVLLPLPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EYTDWGLLPGSEGAFNSSVGDSPAVPAETQQDPELHYLNESASTPAPKLPERSVLLPLPT
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD TPSSGEVLEKEKASQLQEQSSNSSGKEVLMPSHSLPPASLELSSVTVEKSPVLTVTPGST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPSSGEVLEKEKASQLQEQSSNSSGKEVLMPSHSLPPASLELSSVTVEKSPVLTVTPGST
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD EHSIPTPPTSAAPSESTPSELPISPTTAPRTVKELTVSAGDNLIITLPDNEVELKAFVAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EHSIPTPPTSAAPSESTPSELPISPTTAPRTVKELTVSAGDNLIITLPDNEVELKAFVAP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD APPVETTYNYEWNLISHPTDYQGEIKQGHKQTLNLSQLSVGLYVFKVTVSSENAFGEGFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APPVETTYNYEWNLISHPTDYQGEIKQGHKQTLNLSQLSVGLYVFKVTVSSENAFGEGFV
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD NVTVKPARRVNLPPVAVVSPQLQELTLPLTSALIDGSQSTDDTEIVSYHWEEINGPFIEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NVTVKPARRVNLPPVAVVSPQLQELTLPLTSALIDGSQSTDDTEIVSYHWEEINGPFIEE
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD KTSVDSPVLRLSNLDPGNYSFRLTVTDSDGATNSTTAALIVNNAVDYPPVANAGPNHTIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTSVDSPVLRLSNLDPGNYSFRLTVTDSDGATNSTTAALIVNNAVDYPPVANAGPNHTIT
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD LPQNSITLNGNQSSDDHQIVLYEWSLGPGSEGKHVVMQGVQTPYLHLSAMQEGDYTFQLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPQNSITLNGNQSSDDHQIVLYEWSLGPGSEGKHVVMQGVQTPYLHLSAMQEGDYTFQLK
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD VTDSSRQQSTAVVTVIVQPENNRPPVAVAGPDKELIFPVESATLDGSSSSDDHGIVFYHW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTDSSRQQSTAVVTVIVQPENNRPPVAVAGPDKELIFPVESATLDGSSSSDDHGIVFYHW
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD EHVRGPSAVEMENIDKAIATVTGLQVGTYHFRLTVKDQQGLSSTSTLTVAVKKENNSPPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EHVRGPSAVEMENIDKAIATVTGLQVGTYHFRLTVKDQQGLSSTSTLTVAVKKENNSPPR
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD ARAGGRHVLVLPNNSITLDGSRSTDDQRIVSYLWIRDGQSPAAGDVIDGSDHSVALQLTN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARAGGRHVLVLPNNSITLDGSRSTDDQRIVSYLWIRDGQSPAAGDVIDGSDHSVALQLTN
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KSD LVEGVYTFHLRVTDSQGASDTDTATVEVQPDPRKSGLVELTLQVGVGQLTEQRKDTLVRQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVEGVYTFHLRVTDSQGASDTDTATVEVQPDPRKSGLVELTLQVGVGQLTEQRKDTLVRQ
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KSD LAVLLNVLDSDIKVQKIRAHSDLSTVIVFYVQSRPPFKVLKAAEVARNLHMRLSKEKADF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAVLLNVLDSDIKVQKIRAHSDLSTVIVFYVQSRPPFKVLKAAEVARNLHMRLSKEKADF
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KSD LLFKVLRVDTAGCLLKCSGHGHCDPLTKRCICSHLWMENLIQRYIWDGESNCEWSIFYVT
       :::::::::::::::::::::::::::::::::::::::::::::::::::::  :    
XP_016 LLFKVLRVDTAGCLLKCSGHGHCDPLTKRCICSHLWMENLIQRYIWDGESNCEEEIRTCR
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KSD VLAFTLIVLTGGFTWLCICCCKRQKRTKIRKKTKYTILDNMDEQERMELRPKYGIKHRST
                                                                   
XP_016 ETSGARRHRGKIMGGHGKKAAIYKPR                                  
              970       980                                        




1072 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 01:15:55 2016 done: Thu Nov  3 01:15:57 2016
 Total Scan time: 13.490 Total Display time:  0.360

Function used was FASTA [36.3.4 Apr, 2011]
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