Result of FASTA (omim) for pF1KSDA0317
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KSDA0317, 823 aa
  1>>>pF1KSDA0317 823 - 823 aa - 823 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.7781+/-0.000429; mu= 17.9100+/- 0.027
 mean_var=79.5555+/-15.778, 0's: 0 Z-trim(111.5): 267  B-trim: 285 in 1/50
 Lambda= 0.143793
 statistics sampled from 19799 (20078) to 19799 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.604), E-opt: 0.2 (0.235), width:  16
 Scan time: 11.480

The best scores are:                                      opt bits E(85289)
XP_011535717 (OMIM: 615380) PREDICTED: apoptosis-r ( 823) 5556 1163.1       0
NP_001034568 (OMIM: 615380) apoptosis-resistant E3 ( 823) 5556 1163.1       0
XP_006720407 (OMIM: 615380) PREDICTED: apoptosis-r ( 813) 5000 1047.8       0
XP_005268301 (OMIM: 615380) PREDICTED: apoptosis-r ( 662) 4469 937.6       0
XP_011535719 (OMIM: 615380) PREDICTED: apoptosis-r ( 662) 4469 937.6       0
XP_011535718 (OMIM: 615380) PREDICTED: apoptosis-r ( 763) 3634 764.4       0
XP_016884695 (OMIM: 300697,300706) PREDICTED: E3 u (4367)  716 159.5   3e-37
NP_113584 (OMIM: 300697,300706) E3 ubiquitin-prote (4374)  716 159.5   3e-37
XP_005262022 (OMIM: 300697,300706) PREDICTED: E3 u (4374)  716 159.5   3e-37
XP_016884694 (OMIM: 300697,300706) PREDICTED: E3 u (4377)  716 159.5   3e-37
XP_016884693 (OMIM: 300697,300706) PREDICTED: E3 u (4418)  716 159.5 3.1e-37
XP_011529053 (OMIM: 300697,300706) PREDICTED: E3 u (4457)  716 159.5 3.1e-37
XP_011529049 (OMIM: 300697,300706) PREDICTED: E3 u (4457)  716 159.5 3.1e-37
XP_016884690 (OMIM: 300697,300706) PREDICTED: E3 u (4464)  716 159.5 3.1e-37
XP_016884687 (OMIM: 300697,300706) PREDICTED: E3 u (4464)  716 159.5 3.1e-37
XP_016884691 (OMIM: 300697,300706) PREDICTED: E3 u (4464)  716 159.5 3.1e-37
XP_016884688 (OMIM: 300697,300706) PREDICTED: E3 u (4464)  716 159.5 3.1e-37
XP_016884689 (OMIM: 300697,300706) PREDICTED: E3 u (4464)  716 159.5 3.1e-37
XP_016884692 (OMIM: 300697,300706) PREDICTED: E3 u (4464)  716 159.5 3.1e-37
XP_016884686 (OMIM: 300697,300706) PREDICTED: E3 u (4468)  716 159.5 3.1e-37
XP_016884685 (OMIM: 300697,300706) PREDICTED: E3 u (4484)  716 159.5 3.1e-37
XP_016884684 (OMIM: 300697,300706) PREDICTED: E3 u (4485)  716 159.5 3.1e-37
XP_016884683 (OMIM: 300697,300706) PREDICTED: E3 u (4486)  716 159.5 3.1e-37
XP_016884682 (OMIM: 300697,300706) PREDICTED: E3 u (4494)  716 159.5 3.1e-37
XP_016884681 (OMIM: 300697,300706) PREDICTED: E3 u (4500)  716 159.5 3.1e-37
XP_016884680 (OMIM: 300697,300706) PREDICTED: E3 u (4501)  716 159.5 3.1e-37
NP_955456 (OMIM: 602308) NEDD4-like E3 ubiquitin-p ( 431)  685 152.5 3.8e-36
NP_001257382 (OMIM: 602308) NEDD4-like E3 ubiquiti ( 754)  685 152.6 6.1e-36
XP_011521128 (OMIM: 602308) PREDICTED: NEDD4-like  ( 754)  685 152.6 6.1e-36
XP_016878369 (OMIM: 602308) PREDICTED: NEDD4-like  ( 870)  685 152.6 6.8e-36
NP_008945 (OMIM: 602308) NEDD4-like E3 ubiquitin-p ( 870)  685 152.6 6.8e-36
XP_016878370 (OMIM: 602308) PREDICTED: NEDD4-like  ( 870)  685 152.6 6.8e-36
XP_011521125 (OMIM: 602308) PREDICTED: NEDD4-like  ( 870)  685 152.6 6.8e-36
XP_016878368 (OMIM: 602308) PREDICTED: NEDD4-like  ( 870)  685 152.6 6.8e-36
XP_011521127 (OMIM: 602308) PREDICTED: NEDD4-like  ( 870)  685 152.6 6.8e-36
NP_001257383 (OMIM: 602308) NEDD4-like E3 ubiquiti ( 870)  685 152.6 6.8e-36
XP_011527381 (OMIM: 606409,613385) PREDICTED: E3 u ( 692)  675 150.5 2.4e-35
XP_005260627 (OMIM: 606409,613385) PREDICTED: E3 u ( 692)  675 150.5 2.4e-35
NP_001244067 (OMIM: 606409,613385) E3 ubiquitin-pr ( 752)  675 150.5 2.6e-35
XP_016883580 (OMIM: 606409,613385) PREDICTED: E3 u ( 752)  675 150.5 2.6e-35
NP_001311127 (OMIM: 606409,613385) E3 ubiquitin-pr ( 862)  675 150.6 2.9e-35
NP_113671 (OMIM: 606409,613385) E3 ubiquitin-prote ( 862)  675 150.6 2.9e-35
XP_016883579 (OMIM: 606409,613385) PREDICTED: E3 u ( 900)  675 150.6   3e-35
XP_016883578 (OMIM: 606409,613385) PREDICTED: E3 u ( 903)  675 150.6   3e-35
NP_001311126 (OMIM: 606409,613385) E3 ubiquitin-pr ( 903)  675 150.6   3e-35
NP_001244066 (OMIM: 606409,613385) E3 ubiquitin-pr ( 903)  675 150.6   3e-35
XP_016868484 (OMIM: 602307) PREDICTED: NEDD4-like  ( 743)  644 144.1 2.2e-33
XP_016868485 (OMIM: 602307) PREDICTED: NEDD4-like  ( 743)  644 144.1 2.2e-33
XP_016868482 (OMIM: 602307) PREDICTED: NEDD4-like  ( 921)  644 144.2 2.6e-33
XP_005250818 (OMIM: 602307) PREDICTED: NEDD4-like  ( 921)  644 144.2 2.6e-33


>>XP_011535717 (OMIM: 615380) PREDICTED: apoptosis-resis  (823 aa)
 initn: 5556 init1: 5556 opt: 5556  Z-score: 6226.8  bits: 1163.1 E(85289):    0
Smith-Waterman score: 5556; 100.0% identity (100.0% similar) in 823 aa overlap (1-823:1-823)

               10        20        30        40        50        60
pF1KSD MFYVIGGITVSVVAFFFTIKFLFELAARVVSFLQNEDRERRGDRTIYDYVRGNYLDPRSC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MFYVIGGITVSVVAFFFTIKFLFELAARVVSFLQNEDRERRGDRTIYDYVRGNYLDPRSC
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD KVSWDWKDPYEVGHSMAFRVHLFYKNGQPFPAHRPVGLRVHISHVELAVEIPVTQEVLQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KVSWDWKDPYEVGHSMAFRVHLFYKNGQPFPAHRPVGLRVHISHVELAVEIPVTQEVLQE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD PNSNVVKVAFTVRKAGRYEITVKLGGLNVAYSPYYKIFQPGMVVPSKTKIVCHFSTLVLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PNSNVVKVAFTVRKAGRYEITVKLGGLNVAYSPYYKIFQPGMVVPSKTKIVCHFSTLVLT
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD CGQPHTLQIVPRDEYDNPTNNSMSLRDEHNYTLSIHELGPQEEESTGVSFEKSVTSNRQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CGQPHTLQIVPRDEYDNPTNNSMSLRDEHNYTLSIHELGPQEEESTGVSFEKSVTSNRQT
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD FQVFLRLTLHSRGCFHACISYQNQPINNGEFDIIVLSEDEKNIVERNVSTSGVSIYFEAY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FQVFLRLTLHSRGCFHACISYQNQPINNGEFDIIVLSEDEKNIVERNVSTSGVSIYFEAY
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD LYNATNCSSTPWHLPPMHMTSSQRRPSTAVDEEDEDSPSECHTPEKVKKPKKVYCYVSPK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LYNATNCSSTPWHLPPMHMTSSQRRPSTAVDEEDEDSPSECHTPEKVKKPKKVYCYVSPK
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD QFSVKEFYLKIIPWRLYTFRVCPGTKFSYLGPDPVHKLLTLVVDDGIQPPVELSCKERNI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QFSVKEFYLKIIPWRLYTFRVCPGTKFSYLGPDPVHKLLTLVVDDGIQPPVELSCKERNI
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD LAATFIRSLHKNIGGSETFQDKVNFFQRELRQVHMKRPHSKVTLKVSRHALLESSLKATR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAATFIRSLHKNIGGSETFQDKVNFFQRELRQVHMKRPHSKVTLKVSRHALLESSLKATR
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD NFSISDWSKNFEVVFQDEEALDWGGPRREWFELICKALFDTTNQLFTRFSDNNQALVHPN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NFSISDWSKNFEVVFQDEEALDWGGPRREWFELICKALFDTTNQLFTRFSDNNQALVHPN
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD PNRPAHLRLKMYEFAGRLVGKCLYESSLGGAYKQLVRARFTRSFLAQIIGLRMHYKYFET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PNRPAHLRLKMYEFAGRLVGKCLYESSLGGAYKQLVRARFTRSFLAQIIGLRMHYKYFET
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD DDPEFYKSKVCFILNNDMSEMELVFAEEKYNKSGQLDKVVELMTGGAQTPVTNANKIFYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DDPEFYKSKVCFILNNDMSEMELVFAEEKYNKSGQLDKVVELMTGGAQTPVTNANKIFYL
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD NLLAQYRLASQVKEEVEHFLKGLNELVPENLLAIFDENELELLMCGTGDISVSDFKAHAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLLAQYRLASQVKEEVEHFLKGLNELVPENLLAIFDENELELLMCGTGDISVSDFKAHAV
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD VVGGSWHFREKVMRWFWTVVSSLTQEELARLLQFTTGSSQLPPGGFAALCPSFQIIAAPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVGGSWHFREKVMRWFWTVVSSLTQEELARLLQFTTGSSQLPPGGFAALCPSFQIIAAPT
              730       740       750       760       770       780

              790       800       810       820   
pF1KSD HSTLPTAHTCFNQLCLPTYDSYEEVHRMLQLAISEGCEGFGML
       :::::::::::::::::::::::::::::::::::::::::::
XP_011 HSTLPTAHTCFNQLCLPTYDSYEEVHRMLQLAISEGCEGFGML
              790       800       810       820   

>>NP_001034568 (OMIM: 615380) apoptosis-resistant E3 ubi  (823 aa)
 initn: 5556 init1: 5556 opt: 5556  Z-score: 6226.8  bits: 1163.1 E(85289):    0
Smith-Waterman score: 5556; 100.0% identity (100.0% similar) in 823 aa overlap (1-823:1-823)

               10        20        30        40        50        60
pF1KSD MFYVIGGITVSVVAFFFTIKFLFELAARVVSFLQNEDRERRGDRTIYDYVRGNYLDPRSC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MFYVIGGITVSVVAFFFTIKFLFELAARVVSFLQNEDRERRGDRTIYDYVRGNYLDPRSC
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD KVSWDWKDPYEVGHSMAFRVHLFYKNGQPFPAHRPVGLRVHISHVELAVEIPVTQEVLQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVSWDWKDPYEVGHSMAFRVHLFYKNGQPFPAHRPVGLRVHISHVELAVEIPVTQEVLQE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD PNSNVVKVAFTVRKAGRYEITVKLGGLNVAYSPYYKIFQPGMVVPSKTKIVCHFSTLVLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PNSNVVKVAFTVRKAGRYEITVKLGGLNVAYSPYYKIFQPGMVVPSKTKIVCHFSTLVLT
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD CGQPHTLQIVPRDEYDNPTNNSMSLRDEHNYTLSIHELGPQEEESTGVSFEKSVTSNRQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CGQPHTLQIVPRDEYDNPTNNSMSLRDEHNYTLSIHELGPQEEESTGVSFEKSVTSNRQT
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD FQVFLRLTLHSRGCFHACISYQNQPINNGEFDIIVLSEDEKNIVERNVSTSGVSIYFEAY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FQVFLRLTLHSRGCFHACISYQNQPINNGEFDIIVLSEDEKNIVERNVSTSGVSIYFEAY
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD LYNATNCSSTPWHLPPMHMTSSQRRPSTAVDEEDEDSPSECHTPEKVKKPKKVYCYVSPK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LYNATNCSSTPWHLPPMHMTSSQRRPSTAVDEEDEDSPSECHTPEKVKKPKKVYCYVSPK
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD QFSVKEFYLKIIPWRLYTFRVCPGTKFSYLGPDPVHKLLTLVVDDGIQPPVELSCKERNI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QFSVKEFYLKIIPWRLYTFRVCPGTKFSYLGPDPVHKLLTLVVDDGIQPPVELSCKERNI
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD LAATFIRSLHKNIGGSETFQDKVNFFQRELRQVHMKRPHSKVTLKVSRHALLESSLKATR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAATFIRSLHKNIGGSETFQDKVNFFQRELRQVHMKRPHSKVTLKVSRHALLESSLKATR
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD NFSISDWSKNFEVVFQDEEALDWGGPRREWFELICKALFDTTNQLFTRFSDNNQALVHPN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NFSISDWSKNFEVVFQDEEALDWGGPRREWFELICKALFDTTNQLFTRFSDNNQALVHPN
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD PNRPAHLRLKMYEFAGRLVGKCLYESSLGGAYKQLVRARFTRSFLAQIIGLRMHYKYFET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PNRPAHLRLKMYEFAGRLVGKCLYESSLGGAYKQLVRARFTRSFLAQIIGLRMHYKYFET
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD DDPEFYKSKVCFILNNDMSEMELVFAEEKYNKSGQLDKVVELMTGGAQTPVTNANKIFYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DDPEFYKSKVCFILNNDMSEMELVFAEEKYNKSGQLDKVVELMTGGAQTPVTNANKIFYL
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD NLLAQYRLASQVKEEVEHFLKGLNELVPENLLAIFDENELELLMCGTGDISVSDFKAHAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLLAQYRLASQVKEEVEHFLKGLNELVPENLLAIFDENELELLMCGTGDISVSDFKAHAV
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD VVGGSWHFREKVMRWFWTVVSSLTQEELARLLQFTTGSSQLPPGGFAALCPSFQIIAAPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVGGSWHFREKVMRWFWTVVSSLTQEELARLLQFTTGSSQLPPGGFAALCPSFQIIAAPT
              730       740       750       760       770       780

              790       800       810       820   
pF1KSD HSTLPTAHTCFNQLCLPTYDSYEEVHRMLQLAISEGCEGFGML
       :::::::::::::::::::::::::::::::::::::::::::
NP_001 HSTLPTAHTCFNQLCLPTYDSYEEVHRMLQLAISEGCEGFGML
              790       800       810       820   

>>XP_006720407 (OMIM: 615380) PREDICTED: apoptosis-resis  (813 aa)
 initn: 4998 init1: 4998 opt: 5000  Z-score: 5603.6  bits: 1047.8 E(85289):    0
Smith-Waterman score: 5456; 98.8% identity (98.8% similar) in 823 aa overlap (1-823:1-813)

               10        20        30        40        50        60
pF1KSD MFYVIGGITVSVVAFFFTIKFLFELAARVVSFLQNEDRERRGDRTIYDYVRGNYLDPRSC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MFYVIGGITVSVVAFFFTIKFLFELAARVVSFLQNEDRERRGDRTIYDYVRGNYLDPRSC
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD KVSWDWKDPYEVGHSMAFRVHLFYKNGQPFPAHRPVGLRVHISHVELAVEIPVTQEVLQE
       :::::::::::          :::::::::::::::::::::::::::::::::::::::
XP_006 KVSWDWKDPYE----------LFYKNGQPFPAHRPVGLRVHISHVELAVEIPVTQEVLQE
               70                  80        90       100       110

              130       140       150       160       170       180
pF1KSD PNSNVVKVAFTVRKAGRYEITVKLGGLNVAYSPYYKIFQPGMVVPSKTKIVCHFSTLVLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PNSNVVKVAFTVRKAGRYEITVKLGGLNVAYSPYYKIFQPGMVVPSKTKIVCHFSTLVLT
              120       130       140       150       160       170

              190       200       210       220       230       240
pF1KSD CGQPHTLQIVPRDEYDNPTNNSMSLRDEHNYTLSIHELGPQEEESTGVSFEKSVTSNRQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CGQPHTLQIVPRDEYDNPTNNSMSLRDEHNYTLSIHELGPQEEESTGVSFEKSVTSNRQT
              180       190       200       210       220       230

              250       260       270       280       290       300
pF1KSD FQVFLRLTLHSRGCFHACISYQNQPINNGEFDIIVLSEDEKNIVERNVSTSGVSIYFEAY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FQVFLRLTLHSRGCFHACISYQNQPINNGEFDIIVLSEDEKNIVERNVSTSGVSIYFEAY
              240       250       260       270       280       290

              310       320       330       340       350       360
pF1KSD LYNATNCSSTPWHLPPMHMTSSQRRPSTAVDEEDEDSPSECHTPEKVKKPKKVYCYVSPK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LYNATNCSSTPWHLPPMHMTSSQRRPSTAVDEEDEDSPSECHTPEKVKKPKKVYCYVSPK
              300       310       320       330       340       350

              370       380       390       400       410       420
pF1KSD QFSVKEFYLKIIPWRLYTFRVCPGTKFSYLGPDPVHKLLTLVVDDGIQPPVELSCKERNI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QFSVKEFYLKIIPWRLYTFRVCPGTKFSYLGPDPVHKLLTLVVDDGIQPPVELSCKERNI
              360       370       380       390       400       410

              430       440       450       460       470       480
pF1KSD LAATFIRSLHKNIGGSETFQDKVNFFQRELRQVHMKRPHSKVTLKVSRHALLESSLKATR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LAATFIRSLHKNIGGSETFQDKVNFFQRELRQVHMKRPHSKVTLKVSRHALLESSLKATR
              420       430       440       450       460       470

              490       500       510       520       530       540
pF1KSD NFSISDWSKNFEVVFQDEEALDWGGPRREWFELICKALFDTTNQLFTRFSDNNQALVHPN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NFSISDWSKNFEVVFQDEEALDWGGPRREWFELICKALFDTTNQLFTRFSDNNQALVHPN
              480       490       500       510       520       530

              550       560       570       580       590       600
pF1KSD PNRPAHLRLKMYEFAGRLVGKCLYESSLGGAYKQLVRARFTRSFLAQIIGLRMHYKYFET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PNRPAHLRLKMYEFAGRLVGKCLYESSLGGAYKQLVRARFTRSFLAQIIGLRMHYKYFET
              540       550       560       570       580       590

              610       620       630       640       650       660
pF1KSD DDPEFYKSKVCFILNNDMSEMELVFAEEKYNKSGQLDKVVELMTGGAQTPVTNANKIFYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DDPEFYKSKVCFILNNDMSEMELVFAEEKYNKSGQLDKVVELMTGGAQTPVTNANKIFYL
              600       610       620       630       640       650

              670       680       690       700       710       720
pF1KSD NLLAQYRLASQVKEEVEHFLKGLNELVPENLLAIFDENELELLMCGTGDISVSDFKAHAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NLLAQYRLASQVKEEVEHFLKGLNELVPENLLAIFDENELELLMCGTGDISVSDFKAHAV
              660       670       680       690       700       710

              730       740       750       760       770       780
pF1KSD VVGGSWHFREKVMRWFWTVVSSLTQEELARLLQFTTGSSQLPPGGFAALCPSFQIIAAPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VVGGSWHFREKVMRWFWTVVSSLTQEELARLLQFTTGSSQLPPGGFAALCPSFQIIAAPT
              720       730       740       750       760       770

              790       800       810       820   
pF1KSD HSTLPTAHTCFNQLCLPTYDSYEEVHRMLQLAISEGCEGFGML
       :::::::::::::::::::::::::::::::::::::::::::
XP_006 HSTLPTAHTCFNQLCLPTYDSYEEVHRMLQLAISEGCEGFGML
              780       790       800       810   

>>XP_005268301 (OMIM: 615380) PREDICTED: apoptosis-resis  (662 aa)
 initn: 4469 init1: 4469 opt: 4469  Z-score: 5009.6  bits: 937.6 E(85289):    0
Smith-Waterman score: 4469; 100.0% identity (100.0% similar) in 662 aa overlap (162-823:1-662)

             140       150       160       170       180       190 
pF1KSD VRKAGRYEITVKLGGLNVAYSPYYKIFQPGMVVPSKTKIVCHFSTLVLTCGQPHTLQIVP
                                     ::::::::::::::::::::::::::::::
XP_005                               MVVPSKTKIVCHFSTLVLTCGQPHTLQIVP
                                             10        20        30

             200       210       220       230       240       250 
pF1KSD RDEYDNPTNNSMSLRDEHNYTLSIHELGPQEEESTGVSFEKSVTSNRQTFQVFLRLTLHS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RDEYDNPTNNSMSLRDEHNYTLSIHELGPQEEESTGVSFEKSVTSNRQTFQVFLRLTLHS
               40        50        60        70        80        90

             260       270       280       290       300       310 
pF1KSD RGCFHACISYQNQPINNGEFDIIVLSEDEKNIVERNVSTSGVSIYFEAYLYNATNCSSTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RGCFHACISYQNQPINNGEFDIIVLSEDEKNIVERNVSTSGVSIYFEAYLYNATNCSSTP
              100       110       120       130       140       150

             320       330       340       350       360       370 
pF1KSD WHLPPMHMTSSQRRPSTAVDEEDEDSPSECHTPEKVKKPKKVYCYVSPKQFSVKEFYLKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WHLPPMHMTSSQRRPSTAVDEEDEDSPSECHTPEKVKKPKKVYCYVSPKQFSVKEFYLKI
              160       170       180       190       200       210

             380       390       400       410       420       430 
pF1KSD IPWRLYTFRVCPGTKFSYLGPDPVHKLLTLVVDDGIQPPVELSCKERNILAATFIRSLHK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IPWRLYTFRVCPGTKFSYLGPDPVHKLLTLVVDDGIQPPVELSCKERNILAATFIRSLHK
              220       230       240       250       260       270

             440       450       460       470       480       490 
pF1KSD NIGGSETFQDKVNFFQRELRQVHMKRPHSKVTLKVSRHALLESSLKATRNFSISDWSKNF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NIGGSETFQDKVNFFQRELRQVHMKRPHSKVTLKVSRHALLESSLKATRNFSISDWSKNF
              280       290       300       310       320       330

             500       510       520       530       540       550 
pF1KSD EVVFQDEEALDWGGPRREWFELICKALFDTTNQLFTRFSDNNQALVHPNPNRPAHLRLKM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EVVFQDEEALDWGGPRREWFELICKALFDTTNQLFTRFSDNNQALVHPNPNRPAHLRLKM
              340       350       360       370       380       390

             560       570       580       590       600       610 
pF1KSD YEFAGRLVGKCLYESSLGGAYKQLVRARFTRSFLAQIIGLRMHYKYFETDDPEFYKSKVC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YEFAGRLVGKCLYESSLGGAYKQLVRARFTRSFLAQIIGLRMHYKYFETDDPEFYKSKVC
              400       410       420       430       440       450

             620       630       640       650       660       670 
pF1KSD FILNNDMSEMELVFAEEKYNKSGQLDKVVELMTGGAQTPVTNANKIFYLNLLAQYRLASQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FILNNDMSEMELVFAEEKYNKSGQLDKVVELMTGGAQTPVTNANKIFYLNLLAQYRLASQ
              460       470       480       490       500       510

             680       690       700       710       720       730 
pF1KSD VKEEVEHFLKGLNELVPENLLAIFDENELELLMCGTGDISVSDFKAHAVVVGGSWHFREK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VKEEVEHFLKGLNELVPENLLAIFDENELELLMCGTGDISVSDFKAHAVVVGGSWHFREK
              520       530       540       550       560       570

             740       750       760       770       780       790 
pF1KSD VMRWFWTVVSSLTQEELARLLQFTTGSSQLPPGGFAALCPSFQIIAAPTHSTLPTAHTCF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VMRWFWTVVSSLTQEELARLLQFTTGSSQLPPGGFAALCPSFQIIAAPTHSTLPTAHTCF
              580       590       600       610       620       630

             800       810       820   
pF1KSD NQLCLPTYDSYEEVHRMLQLAISEGCEGFGML
       ::::::::::::::::::::::::::::::::
XP_005 NQLCLPTYDSYEEVHRMLQLAISEGCEGFGML
              640       650       660  

>>XP_011535719 (OMIM: 615380) PREDICTED: apoptosis-resis  (662 aa)
 initn: 4469 init1: 4469 opt: 4469  Z-score: 5009.6  bits: 937.6 E(85289):    0
Smith-Waterman score: 4469; 100.0% identity (100.0% similar) in 662 aa overlap (162-823:1-662)

             140       150       160       170       180       190 
pF1KSD VRKAGRYEITVKLGGLNVAYSPYYKIFQPGMVVPSKTKIVCHFSTLVLTCGQPHTLQIVP
                                     ::::::::::::::::::::::::::::::
XP_011                               MVVPSKTKIVCHFSTLVLTCGQPHTLQIVP
                                             10        20        30

             200       210       220       230       240       250 
pF1KSD RDEYDNPTNNSMSLRDEHNYTLSIHELGPQEEESTGVSFEKSVTSNRQTFQVFLRLTLHS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RDEYDNPTNNSMSLRDEHNYTLSIHELGPQEEESTGVSFEKSVTSNRQTFQVFLRLTLHS
               40        50        60        70        80        90

             260       270       280       290       300       310 
pF1KSD RGCFHACISYQNQPINNGEFDIIVLSEDEKNIVERNVSTSGVSIYFEAYLYNATNCSSTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RGCFHACISYQNQPINNGEFDIIVLSEDEKNIVERNVSTSGVSIYFEAYLYNATNCSSTP
              100       110       120       130       140       150

             320       330       340       350       360       370 
pF1KSD WHLPPMHMTSSQRRPSTAVDEEDEDSPSECHTPEKVKKPKKVYCYVSPKQFSVKEFYLKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WHLPPMHMTSSQRRPSTAVDEEDEDSPSECHTPEKVKKPKKVYCYVSPKQFSVKEFYLKI
              160       170       180       190       200       210

             380       390       400       410       420       430 
pF1KSD IPWRLYTFRVCPGTKFSYLGPDPVHKLLTLVVDDGIQPPVELSCKERNILAATFIRSLHK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IPWRLYTFRVCPGTKFSYLGPDPVHKLLTLVVDDGIQPPVELSCKERNILAATFIRSLHK
              220       230       240       250       260       270

             440       450       460       470       480       490 
pF1KSD NIGGSETFQDKVNFFQRELRQVHMKRPHSKVTLKVSRHALLESSLKATRNFSISDWSKNF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NIGGSETFQDKVNFFQRELRQVHMKRPHSKVTLKVSRHALLESSLKATRNFSISDWSKNF
              280       290       300       310       320       330

             500       510       520       530       540       550 
pF1KSD EVVFQDEEALDWGGPRREWFELICKALFDTTNQLFTRFSDNNQALVHPNPNRPAHLRLKM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVVFQDEEALDWGGPRREWFELICKALFDTTNQLFTRFSDNNQALVHPNPNRPAHLRLKM
              340       350       360       370       380       390

             560       570       580       590       600       610 
pF1KSD YEFAGRLVGKCLYESSLGGAYKQLVRARFTRSFLAQIIGLRMHYKYFETDDPEFYKSKVC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YEFAGRLVGKCLYESSLGGAYKQLVRARFTRSFLAQIIGLRMHYKYFETDDPEFYKSKVC
              400       410       420       430       440       450

             620       630       640       650       660       670 
pF1KSD FILNNDMSEMELVFAEEKYNKSGQLDKVVELMTGGAQTPVTNANKIFYLNLLAQYRLASQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FILNNDMSEMELVFAEEKYNKSGQLDKVVELMTGGAQTPVTNANKIFYLNLLAQYRLASQ
              460       470       480       490       500       510

             680       690       700       710       720       730 
pF1KSD VKEEVEHFLKGLNELVPENLLAIFDENELELLMCGTGDISVSDFKAHAVVVGGSWHFREK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKEEVEHFLKGLNELVPENLLAIFDENELELLMCGTGDISVSDFKAHAVVVGGSWHFREK
              520       530       540       550       560       570

             740       750       760       770       780       790 
pF1KSD VMRWFWTVVSSLTQEELARLLQFTTGSSQLPPGGFAALCPSFQIIAAPTHSTLPTAHTCF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VMRWFWTVVSSLTQEELARLLQFTTGSSQLPPGGFAALCPSFQIIAAPTHSTLPTAHTCF
              580       590       600       610       620       630

             800       810       820   
pF1KSD NQLCLPTYDSYEEVHRMLQLAISEGCEGFGML
       ::::::::::::::::::::::::::::::::
XP_011 NQLCLPTYDSYEEVHRMLQLAISEGCEGFGML
              640       650       660  

>>XP_011535718 (OMIM: 615380) PREDICTED: apoptosis-resis  (763 aa)
 initn: 5136 init1: 3634 opt: 3634  Z-score: 4072.5  bits: 764.4 E(85289):    0
Smith-Waterman score: 5020; 92.7% identity (92.7% similar) in 823 aa overlap (1-823:1-763)

               10        20        30        40        50        60
pF1KSD MFYVIGGITVSVVAFFFTIKFLFELAARVVSFLQNEDRERRGDRTIYDYVRGNYLDPRSC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MFYVIGGITVSVVAFFFTIKFLFELAARVVSFLQNEDRERRGDRTIYDYVRGNYLDPRSC
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD KVSWDWKDPYEVGHSMAFRVHLFYKNGQPFPAHRPVGLRVHISHVELAVEIPVTQEVLQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KVSWDWKDPYEVGHSMAFRVHLFYKNGQPFPAHRPVGLRVHISHVELAVEIPVTQEVLQE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD PNSNVVKVAFTVRKAGRYEITVKLGGLNVAYSPYYKIFQPGMVVPSKTKIVCHFSTLVLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PNSNVVKVAFTVRKAGRYEITVKLGGLNVAYSPYYKIFQPGMVVPSKTKIVCHFSTLVLT
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD CGQPHTLQIVPRDEYDNPTNNSMSLRDEHNYTLSIHELGPQEEESTGVSFEKSVTSNRQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CGQPHTLQIVPRDEYDNPTNNSMSLRDEHNYTLSIHELGPQEEESTGVSFEKSVTSNRQT
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD FQVFLRLTLHSRGCFHACISYQNQPINNGEFDIIVLSEDEKNIVERNVSTSGVSIYFEAY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FQVFLRLTLHSRGCFHACISYQNQPINNGEFDIIVLSEDEKNIVERNVSTSGVSIYFEAY
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD LYNATNCSSTPWHLPPMHMTSSQRRPSTAVDEEDEDSPSECHTPEKVKKPKKVYCYVSPK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LYNATNCSSTPWHLPPMHMTSSQRRPSTAVDEEDEDSPSECHTPEKVKKPKKVYCYVSPK
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD QFSVKEFYLKIIPWRLYTFRVCPGTKFSYLGPDPVHKLLTLVVDDGIQPPVELSCKERNI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QFSVKEFYLKIIPWRLYTFRVCPGTKFSYLGPDPVHKLLTLVVDDGIQPPVELSCKERNI
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD LAATFIRSLHKNIGGSETFQDKVNFFQRELRQVHMKRPHSKVTLKVSRHALLESSLKATR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAATFIRSLHKNIGGSETFQDKVNFFQRELRQVHMKRPHSKVTLKVSRHALLESSLKATR
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD NFSISDWSKNFEVVFQDEEALDWGGPRREWFELICKALFDTTNQLFTRFSDNNQALVHPN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::    
XP_011 NFSISDWSKNFEVVFQDEEALDWGGPRREWFELICKALFDTTNQLFTRFSDNNQAL----
              490       500       510       520       530          

              550       560       570       580       590       600
pF1KSD PNRPAHLRLKMYEFAGRLVGKCLYESSLGGAYKQLVRARFTRSFLAQIIGLRMHYKYFET
                                                               ::::
XP_011 --------------------------------------------------------YFET
                                                                540

              610       620       630       640       650       660
pF1KSD DDPEFYKSKVCFILNNDMSEMELVFAEEKYNKSGQLDKVVELMTGGAQTPVTNANKIFYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DDPEFYKSKVCFILNNDMSEMELVFAEEKYNKSGQLDKVVELMTGGAQTPVTNANKIFYL
              550       560       570       580       590       600

              670       680       690       700       710       720
pF1KSD NLLAQYRLASQVKEEVEHFLKGLNELVPENLLAIFDENELELLMCGTGDISVSDFKAHAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLLAQYRLASQVKEEVEHFLKGLNELVPENLLAIFDENELELLMCGTGDISVSDFKAHAV
              610       620       630       640       650       660

              730       740       750       760       770       780
pF1KSD VVGGSWHFREKVMRWFWTVVSSLTQEELARLLQFTTGSSQLPPGGFAALCPSFQIIAAPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVGGSWHFREKVMRWFWTVVSSLTQEELARLLQFTTGSSQLPPGGFAALCPSFQIIAAPT
              670       680       690       700       710       720

              790       800       810       820   
pF1KSD HSTLPTAHTCFNQLCLPTYDSYEEVHRMLQLAISEGCEGFGML
       :::::::::::::::::::::::::::::::::::::::::::
XP_011 HSTLPTAHTCFNQLCLPTYDSYEEVHRMLQLAISEGCEGFGML
              730       740       750       760   

>>XP_016884695 (OMIM: 300697,300706) PREDICTED: E3 ubiqu  (4367 aa)
 initn: 596 init1: 197 opt: 716  Z-score: 789.6  bits: 159.5 E(85289): 3e-37
Smith-Waterman score: 723; 34.6% identity (67.2% similar) in 396 aa overlap (439-822:3987-4366)

      410       420       430       440       450       460        
pF1KSD PPVELSCKERNILAATFIRSLHKNIGGSETFQDKVNFFQRELRQVHMKRPHSKVTLKVSR
                                     :. : ..:..::...     .  ....: :
XP_016 TVLNQILRQSTTHLADGPFAVLVDYIRVLDFDVKRKYFRQELERLDEGLRKEDMAVHVRR
       3960      3970      3980      3990      4000      4010      

      470       480       490       500       510       520        
pF1KSD HALLESSLKATRNFSISDWSKNFEVVFQDEEALDWGGPRREWFELICKALFDTTNQLFTR
         ..:.: .  .  :  . .. . .::. ::. : ::  :::. .: . .:.    :: :
XP_016 DHVFEDSYRELHRKSPEEMKNRLYIVFEGEEGQDAGGLLREWYMIISREMFNPMYALF-R
       4020      4030      4040      4050      4060      4070      

      530       540          550       560       570       580     
pF1KSD FSDNNQALVHPNPNR---PAHLRLKMYEFAGRLVGKCLYESSLGGAYKQLVRARFTRSFL
        : ....    ::.    : ::  ....:.::.:.: .:..       .:..  ::::: 
XP_016 TSPGDRVTYTINPSSHCNPNHL--SYFKFVGRIVAKAVYDN-------RLLECYFTRSFY
        4080      4090        4100      4110             4120      

         590       600       610       620         630       640   
pF1KSD AQIIGLRMHYKYFETDDPEFYKSKVCFILNNDMSEM--ELVFAEEKYNKSGQLDKVVELM
        .:.:  ..:  .:..: .::.. : ..:.::.: .  .:.:. :  .. : . .: .: 
XP_016 KHILGKSVRYTDMESEDYHFYQGLV-YLLENDVSTLGYDLTFSTE-VQEFG-VCEVRDLK
       4130      4140      4150       4160      4170        4180   

           650       660       670       680       690       700   
pF1KSD TGGAQTPVTNANKIFYLNLLAQYRLASQVKEEVEHFLKGLNELVPENLLAIFDENELELL
        .::.  ::. ::  :..:. :.:... .....  ::.:. :..:. :..:: :.:::::
XP_016 PNGANILVTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKRLISIFTEQELELL
          4190      4200      4210      4220      4230      4240   

           710       720       730       740       750       760   
pF1KSD MCGTGDISVSDFKAHAVVVGGSWHFREKVMRWFWTVVSSLTQEELARLLQFTTGSSQLPP
       . :   :...:.:...     ...     ..::: .. :. : . :..:::.::.:..: 
XP_016 ISGLPTIDIDDLKSNTEY--HKYQSNSIQIQWFWRALRSFDQADRAKFLQFVTGTSKVPL
          4250      4260        4270      4280      4290      4300 

                770       780         790       800       810      
pF1KSD GGFAAL-----CPSFQIIAAPTHST--LPTAHTCFNQLCLPTYDSYEEVHRMLQLAISEG
        :::::       .:::     .::  ::.:::::::: ::.:.:.:....:: :::.: 
XP_016 QGFAALEGMNGIQKFQI-HRDDRSTDRLPSAHTCFNQLDLPAYESFEKLRHMLLLAIQEC
            4310       4320      4330      4340      4350      4360

        820   
pF1KSD CEGFGML
        ::::. 
XP_016 SEGFGLA
              

>>NP_113584 (OMIM: 300697,300706) E3 ubiquitin-protein l  (4374 aa)
 initn: 596 init1: 197 opt: 716  Z-score: 789.6  bits: 159.5 E(85289): 3e-37
Smith-Waterman score: 723; 34.6% identity (67.2% similar) in 396 aa overlap (439-822:3994-4373)

      410       420       430       440       450       460        
pF1KSD PPVELSCKERNILAATFIRSLHKNIGGSETFQDKVNFFQRELRQVHMKRPHSKVTLKVSR
                                     :. : ..:..::...     .  ....: :
NP_113 TVLNQILRQSTTHLADGPFAVLVDYIRVLDFDVKRKYFRQELERLDEGLRKEDMAVHVRR
          3970      3980      3990      4000      4010      4020   

      470       480       490       500       510       520        
pF1KSD HALLESSLKATRNFSISDWSKNFEVVFQDEEALDWGGPRREWFELICKALFDTTNQLFTR
         ..:.: .  .  :  . .. . .::. ::. : ::  :::. .: . .:.    :: :
NP_113 DHVFEDSYRELHRKSPEEMKNRLYIVFEGEEGQDAGGLLREWYMIISREMFNPMYALF-R
          4030      4040      4050      4060      4070      4080   

      530       540          550       560       570       580     
pF1KSD FSDNNQALVHPNPNR---PAHLRLKMYEFAGRLVGKCLYESSLGGAYKQLVRARFTRSFL
        : ....    ::.    : ::  ....:.::.:.: .:..       .:..  ::::: 
NP_113 TSPGDRVTYTINPSSHCNPNHL--SYFKFVGRIVAKAVYDN-------RLLECYFTRSFY
           4090      4100        4110      4120             4130   

         590       600       610       620         630       640   
pF1KSD AQIIGLRMHYKYFETDDPEFYKSKVCFILNNDMSEM--ELVFAEEKYNKSGQLDKVVELM
        .:.:  ..:  .:..: .::.. : ..:.::.: .  .:.:. :  .. : . .: .: 
NP_113 KHILGKSVRYTDMESEDYHFYQGLV-YLLENDVSTLGYDLTFSTE-VQEFG-VCEVRDLK
          4140      4150       4160      4170       4180       4190

           650       660       670       680       690       700   
pF1KSD TGGAQTPVTNANKIFYLNLLAQYRLASQVKEEVEHFLKGLNELVPENLLAIFDENELELL
        .::.  ::. ::  :..:. :.:... .....  ::.:. :..:. :..:: :.:::::
NP_113 PNGANILVTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKRLISIFTEQELELL
             4200      4210      4220      4230      4240      4250

           710       720       730       740       750       760   
pF1KSD MCGTGDISVSDFKAHAVVVGGSWHFREKVMRWFWTVVSSLTQEELARLLQFTTGSSQLPP
       . :   :...:.:...     ...     ..::: .. :. : . :..:::.::.:..: 
NP_113 ISGLPTIDIDDLKSNTEY--HKYQSNSIQIQWFWRALRSFDQADRAKFLQFVTGTSKVPL
             4260        4270      4280      4290      4300        

                770       780         790       800       810      
pF1KSD GGFAAL-----CPSFQIIAAPTHST--LPTAHTCFNQLCLPTYDSYEEVHRMLQLAISEG
        :::::       .:::     .::  ::.:::::::: ::.:.:.:....:: :::.: 
NP_113 QGFAALEGMNGIQKFQI-HRDDRSTDRLPSAHTCFNQLDLPAYESFEKLRHMLLLAIQEC
     4310      4320       4330      4340      4350      4360       

        820   
pF1KSD CEGFGML
        ::::. 
NP_113 SEGFGLA
      4370    

>>XP_005262022 (OMIM: 300697,300706) PREDICTED: E3 ubiqu  (4374 aa)
 initn: 596 init1: 197 opt: 716  Z-score: 789.6  bits: 159.5 E(85289): 3e-37
Smith-Waterman score: 723; 34.6% identity (67.2% similar) in 396 aa overlap (439-822:3994-4373)

      410       420       430       440       450       460        
pF1KSD PPVELSCKERNILAATFIRSLHKNIGGSETFQDKVNFFQRELRQVHMKRPHSKVTLKVSR
                                     :. : ..:..::...     .  ....: :
XP_005 TVLNQILRQSTTHLADGPFAVLVDYIRVLDFDVKRKYFRQELERLDEGLRKEDMAVHVRR
          3970      3980      3990      4000      4010      4020   

      470       480       490       500       510       520        
pF1KSD HALLESSLKATRNFSISDWSKNFEVVFQDEEALDWGGPRREWFELICKALFDTTNQLFTR
         ..:.: .  .  :  . .. . .::. ::. : ::  :::. .: . .:.    :: :
XP_005 DHVFEDSYRELHRKSPEEMKNRLYIVFEGEEGQDAGGLLREWYMIISREMFNPMYALF-R
          4030      4040      4050      4060      4070      4080   

      530       540          550       560       570       580     
pF1KSD FSDNNQALVHPNPNR---PAHLRLKMYEFAGRLVGKCLYESSLGGAYKQLVRARFTRSFL
        : ....    ::.    : ::  ....:.::.:.: .:..       .:..  ::::: 
XP_005 TSPGDRVTYTINPSSHCNPNHL--SYFKFVGRIVAKAVYDN-------RLLECYFTRSFY
           4090      4100        4110      4120             4130   

         590       600       610       620         630       640   
pF1KSD AQIIGLRMHYKYFETDDPEFYKSKVCFILNNDMSEM--ELVFAEEKYNKSGQLDKVVELM
        .:.:  ..:  .:..: .::.. : ..:.::.: .  .:.:. :  .. : . .: .: 
XP_005 KHILGKSVRYTDMESEDYHFYQGLV-YLLENDVSTLGYDLTFSTE-VQEFG-VCEVRDLK
          4140      4150       4160      4170       4180       4190

           650       660       670       680       690       700   
pF1KSD TGGAQTPVTNANKIFYLNLLAQYRLASQVKEEVEHFLKGLNELVPENLLAIFDENELELL
        .::.  ::. ::  :..:. :.:... .....  ::.:. :..:. :..:: :.:::::
XP_005 PNGANILVTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKRLISIFTEQELELL
             4200      4210      4220      4230      4240      4250

           710       720       730       740       750       760   
pF1KSD MCGTGDISVSDFKAHAVVVGGSWHFREKVMRWFWTVVSSLTQEELARLLQFTTGSSQLPP
       . :   :...:.:...     ...     ..::: .. :. : . :..:::.::.:..: 
XP_005 ISGLPTIDIDDLKSNTEY--HKYQSNSIQIQWFWRALRSFDQADRAKFLQFVTGTSKVPL
             4260        4270      4280      4290      4300        

                770       780         790       800       810      
pF1KSD GGFAAL-----CPSFQIIAAPTHST--LPTAHTCFNQLCLPTYDSYEEVHRMLQLAISEG
        :::::       .:::     .::  ::.:::::::: ::.:.:.:....:: :::.: 
XP_005 QGFAALEGMNGIQKFQI-HRDDRSTDRLPSAHTCFNQLDLPAYESFEKLRHMLLLAIQEC
     4310      4320       4330      4340      4350      4360       

        820   
pF1KSD CEGFGML
        ::::. 
XP_005 SEGFGLA
      4370    

>>XP_016884694 (OMIM: 300697,300706) PREDICTED: E3 ubiqu  (4377 aa)
 initn: 596 init1: 197 opt: 716  Z-score: 789.6  bits: 159.5 E(85289): 3e-37
Smith-Waterman score: 723; 34.6% identity (67.2% similar) in 396 aa overlap (439-822:3997-4376)

      410       420       430       440       450       460        
pF1KSD PPVELSCKERNILAATFIRSLHKNIGGSETFQDKVNFFQRELRQVHMKRPHSKVTLKVSR
                                     :. : ..:..::...     .  ....: :
XP_016 TVLNQILRQSTTHLADGPFAVLVDYIRVLDFDVKRKYFRQELERLDEGLRKEDMAVHVRR
       3970      3980      3990      4000      4010      4020      

      470       480       490       500       510       520        
pF1KSD HALLESSLKATRNFSISDWSKNFEVVFQDEEALDWGGPRREWFELICKALFDTTNQLFTR
         ..:.: .  .  :  . .. . .::. ::. : ::  :::. .: . .:.    :: :
XP_016 DHVFEDSYRELHRKSPEEMKNRLYIVFEGEEGQDAGGLLREWYMIISREMFNPMYALF-R
       4030      4040      4050      4060      4070      4080      

      530       540          550       560       570       580     
pF1KSD FSDNNQALVHPNPNR---PAHLRLKMYEFAGRLVGKCLYESSLGGAYKQLVRARFTRSFL
        : ....    ::.    : ::  ....:.::.:.: .:..       .:..  ::::: 
XP_016 TSPGDRVTYTINPSSHCNPNHL--SYFKFVGRIVAKAVYDN-------RLLECYFTRSFY
        4090      4100        4110      4120             4130      

         590       600       610       620         630       640   
pF1KSD AQIIGLRMHYKYFETDDPEFYKSKVCFILNNDMSEM--ELVFAEEKYNKSGQLDKVVELM
        .:.:  ..:  .:..: .::.. : ..:.::.: .  .:.:. :  .. : . .: .: 
XP_016 KHILGKSVRYTDMESEDYHFYQGLV-YLLENDVSTLGYDLTFSTE-VQEFG-VCEVRDLK
       4140      4150      4160       4170      4180        4190   

           650       660       670       680       690       700   
pF1KSD TGGAQTPVTNANKIFYLNLLAQYRLASQVKEEVEHFLKGLNELVPENLLAIFDENELELL
        .::.  ::. ::  :..:. :.:... .....  ::.:. :..:. :..:: :.:::::
XP_016 PNGANILVTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKRLISIFTEQELELL
          4200      4210      4220      4230      4240      4250   

           710       720       730       740       750       760   
pF1KSD MCGTGDISVSDFKAHAVVVGGSWHFREKVMRWFWTVVSSLTQEELARLLQFTTGSSQLPP
       . :   :...:.:...     ...     ..::: .. :. : . :..:::.::.:..: 
XP_016 ISGLPTIDIDDLKSNTEY--HKYQSNSIQIQWFWRALRSFDQADRAKFLQFVTGTSKVPL
          4260      4270        4280      4290      4300      4310 

                770       780         790       800       810      
pF1KSD GGFAAL-----CPSFQIIAAPTHST--LPTAHTCFNQLCLPTYDSYEEVHRMLQLAISEG
        :::::       .:::     .::  ::.:::::::: ::.:.:.:....:: :::.: 
XP_016 QGFAALEGMNGIQKFQI-HRDDRSTDRLPSAHTCFNQLDLPAYESFEKLRHMLLLAIQEC
            4320       4330      4340      4350      4360      4370

        820   
pF1KSD CEGFGML
        ::::. 
XP_016 SEGFGLA
              




823 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 01:15:09 2016 done: Thu Nov  3 01:15:11 2016
 Total Scan time: 11.480 Total Display time:  0.220

Function used was FASTA [36.3.4 Apr, 2011]
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