Result of FASTA (omim) for pF1KSDA0251
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KSDA0251, 788 aa
  1>>>pF1KSDA0251 788 - 788 aa - 788 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.3954+/-0.000345; mu= 15.8630+/- 0.022
 mean_var=100.1377+/-20.252, 0's: 0 Z-trim(116.2): 55  B-trim: 0 in 0/56
 Lambda= 0.128167
 statistics sampled from 27098 (27153) to 27098 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.679), E-opt: 0.2 (0.318), width:  16
 Scan time: 12.950

The best scores are:                                      opt bits E(85289)
NP_055842 (OMIM: 614244) pyridoxal-dependent decar ( 788) 5203 973.0       0
NP_001310948 (OMIM: 614244) pyridoxal-dependent de ( 787) 5184 969.5       0
XP_016878549 (OMIM: 614244) PREDICTED: pyridoxal-d ( 797) 5169 966.7       0
XP_005255230 (OMIM: 614244) PREDICTED: pyridoxal-d ( 806) 5162 965.4       0
XP_016878548 (OMIM: 614244) PREDICTED: pyridoxal-d ( 773) 5112 956.1       0
XP_005255233 (OMIM: 614244) PREDICTED: pyridoxal-d ( 773) 5112 956.1       0
XP_016878550 (OMIM: 614244) PREDICTED: pyridoxal-d ( 773) 5112 956.1       0
NP_001272376 (OMIM: 614244) pyridoxal-dependent de ( 773) 5112 956.1       0
XP_016878551 (OMIM: 614244) PREDICTED: pyridoxal-d ( 773) 5112 956.1       0
XP_016878553 (OMIM: 614244) PREDICTED: pyridoxal-d ( 746) 4693 878.7       0
XP_006720928 (OMIM: 614244) PREDICTED: pyridoxal-d ( 746) 4693 878.7       0
NP_001272374 (OMIM: 614244) pyridoxal-dependent de ( 760) 4693 878.7       0
NP_001272373 (OMIM: 614244) pyridoxal-dependent de ( 761) 4693 878.7       0
XP_016878552 (OMIM: 614244) PREDICTED: pyridoxal-d ( 708) 4540 850.4       0
NP_001272377 (OMIM: 614244) pyridoxal-dependent de ( 697) 4365 818.0       0
NP_001272378 (OMIM: 614244) pyridoxal-dependent de ( 498) 3120 587.7 4.1e-167
NP_001310949 (OMIM: 614244) pyridoxal-dependent de ( 497) 3101 584.2 4.7e-166
XP_016878554 (OMIM: 614244) PREDICTED: pyridoxal-d ( 483) 3029 570.9 4.6e-162
NP_001310950 (OMIM: 614244) pyridoxal-dependent de ( 471) 2610 493.4 9.5e-139
NP_001272379 (OMIM: 614244) pyridoxal-dependent de ( 429) 1431 275.3 3.7e-73


>>NP_055842 (OMIM: 614244) pyridoxal-dependent decarboxy  (788 aa)
 initn: 5203 init1: 5203 opt: 5203  Z-score: 5199.9  bits: 973.0 E(85289):    0
Smith-Waterman score: 5203; 100.0% identity (100.0% similar) in 788 aa overlap (1-788:1-788)

               10        20        30        40        50        60
pF1KSD MDASLEKIADPTLAEMGKNLKEAVKMLEDSQRRTEEENGKKLISGDIPGPLQGSGQDMVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MDASLEKIADPTLAEMGKNLKEAVKMLEDSQRRTEEENGKKLISGDIPGPLQGSGQDMVS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD ILQLVQNLMHGDEDEEPQSPRIQNIGEQGHMALLGHSLGAYISTLDKEKLRKLTTRILSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ILQLVQNLMHGDEDEEPQSPRIQNIGEQGHMALLGHSLGAYISTLDKEKLRKLTTRILSD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD TTLWLCRIFRYENGCAYFHEEEREGLAKICRLAIHSRYEDFVVDGFNVLYNKKPVIYLSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TTLWLCRIFRYENGCAYFHEEEREGLAKICRLAIHSRYEDFVVDGFNVLYNKKPVIYLSA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD AARPGLGQYLCNQLGLPFPCLCRVPCNTVFGSQHQMDVAFLEKLIKDDIERGRLPLLLVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 AARPGLGQYLCNQLGLPFPCLCRVPCNTVFGSQHQMDVAFLEKLIKDDIERGRLPLLLVA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD NAGTAAVGHTDKIGRLKELCEQYGIWLHVEGVNLATLALGYVSSSVLAAAKCDSMTMTPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 NAGTAAVGHTDKIGRLKELCEQYGIWLHVEGVNLATLALGYVSSSVLAAAKCDSMTMTPG
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD PWLGLPAVPAVTLYKHDDPALTLVAGLTSNKPTDKLRALPLWLSLQYLGLDGFVERIKHA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PWLGLPAVPAVTLYKHDDPALTLVAGLTSNKPTDKLRALPLWLSLQYLGLDGFVERIKHA
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD CQLSQRLQESLKKVNYIKILVEDELSSPVVVFRFFQELPGSDPVFKAVPVPNMTPSGVGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 CQLSQRLQESLKKVNYIKILVEDELSSPVVVFRFFQELPGSDPVFKAVPVPNMTPSGVGR
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD ERHSCDALNRWLGEQLKQLVPASGLTVMDLEAEGTCLRFSPLMTAAVLGTRGEDVDQLVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ERHSCDALNRWLGEQLKQLVPASGLTVMDLEAEGTCLRFSPLMTAAVLGTRGEDVDQLVA
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD CIESKLPVLCCTLQLREEFKQEVEATAGLLYVDDPNWSGIGVVRYEHANDDKSSLKSDPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 CIESKLPVLCCTLQLREEFKQEVEATAGLLYVDDPNWSGIGVVRYEHANDDKSSLKSDPE
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD GENIHAGLLKKLNELESDLTFKIGPEYKSMKSCLYVGMASDNVDAAELVETIAATAREIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GENIHAGLLKKLNELESDLTFKIGPEYKSMKSCLYVGMASDNVDAAELVETIAATAREIE
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD ENSRLLENMTEVVRKGIQEAQVELQKASEERLLEEGVLRQIPVVGSVLNWFSPVQALQKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ENSRLLENMTEVVRKGIQEAQVELQKASEERLLEEGVLRQIPVVGSVLNWFSPVQALQKG
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD RTFNLTAGSLESTEPIYVYKAQGAGVTLPPTPSGSRTKQRLPGQKPFKRSLRGSDALSET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RTFNLTAGSLESTEPIYVYKAQGAGVTLPPTPSGSRTKQRLPGQKPFKRSLRGSDALSET
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD SSVSHIEDLEKVERLSSGPEQITLEASSTEGHPGAPSPQHTDQTEAFQKGVPHPEDDHSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SSVSHIEDLEKVERLSSGPEQITLEASSTEGHPGAPSPQHTDQTEAFQKGVPHPEDDHSQ
              730       740       750       760       770       780

               
pF1KSD VEGPESLR
       ::::::::
NP_055 VEGPESLR
               

>>NP_001310948 (OMIM: 614244) pyridoxal-dependent decarb  (787 aa)
 initn: 5009 init1: 5009 opt: 5184  Z-score: 5180.9  bits: 969.5 E(85289):    0
Smith-Waterman score: 5184; 99.9% identity (99.9% similar) in 788 aa overlap (1-788:1-787)

               10        20        30        40        50        60
pF1KSD MDASLEKIADPTLAEMGKNLKEAVKMLEDSQRRTEEENGKKLISGDIPGPLQGSGQDMVS
       :::::::::::::::::::::::::::::::: :::::::::::::::::::::::::::
NP_001 MDASLEKIADPTLAEMGKNLKEAVKMLEDSQR-TEEENGKKLISGDIPGPLQGSGQDMVS
               10        20        30         40        50         

               70        80        90       100       110       120
pF1KSD ILQLVQNLMHGDEDEEPQSPRIQNIGEQGHMALLGHSLGAYISTLDKEKLRKLTTRILSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILQLVQNLMHGDEDEEPQSPRIQNIGEQGHMALLGHSLGAYISTLDKEKLRKLTTRILSD
      60        70        80        90       100       110         

              130       140       150       160       170       180
pF1KSD TTLWLCRIFRYENGCAYFHEEEREGLAKICRLAIHSRYEDFVVDGFNVLYNKKPVIYLSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTLWLCRIFRYENGCAYFHEEEREGLAKICRLAIHSRYEDFVVDGFNVLYNKKPVIYLSA
     120       130       140       150       160       170         

              190       200       210       220       230       240
pF1KSD AARPGLGQYLCNQLGLPFPCLCRVPCNTVFGSQHQMDVAFLEKLIKDDIERGRLPLLLVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AARPGLGQYLCNQLGLPFPCLCRVPCNTVFGSQHQMDVAFLEKLIKDDIERGRLPLLLVA
     180       190       200       210       220       230         

              250       260       270       280       290       300
pF1KSD NAGTAAVGHTDKIGRLKELCEQYGIWLHVEGVNLATLALGYVSSSVLAAAKCDSMTMTPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NAGTAAVGHTDKIGRLKELCEQYGIWLHVEGVNLATLALGYVSSSVLAAAKCDSMTMTPG
     240       250       260       270       280       290         

              310       320       330       340       350       360
pF1KSD PWLGLPAVPAVTLYKHDDPALTLVAGLTSNKPTDKLRALPLWLSLQYLGLDGFVERIKHA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PWLGLPAVPAVTLYKHDDPALTLVAGLTSNKPTDKLRALPLWLSLQYLGLDGFVERIKHA
     300       310       320       330       340       350         

              370       380       390       400       410       420
pF1KSD CQLSQRLQESLKKVNYIKILVEDELSSPVVVFRFFQELPGSDPVFKAVPVPNMTPSGVGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CQLSQRLQESLKKVNYIKILVEDELSSPVVVFRFFQELPGSDPVFKAVPVPNMTPSGVGR
     360       370       380       390       400       410         

              430       440       450       460       470       480
pF1KSD ERHSCDALNRWLGEQLKQLVPASGLTVMDLEAEGTCLRFSPLMTAAVLGTRGEDVDQLVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERHSCDALNRWLGEQLKQLVPASGLTVMDLEAEGTCLRFSPLMTAAVLGTRGEDVDQLVA
     420       430       440       450       460       470         

              490       500       510       520       530       540
pF1KSD CIESKLPVLCCTLQLREEFKQEVEATAGLLYVDDPNWSGIGVVRYEHANDDKSSLKSDPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CIESKLPVLCCTLQLREEFKQEVEATAGLLYVDDPNWSGIGVVRYEHANDDKSSLKSDPE
     480       490       500       510       520       530         

              550       560       570       580       590       600
pF1KSD GENIHAGLLKKLNELESDLTFKIGPEYKSMKSCLYVGMASDNVDAAELVETIAATAREIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GENIHAGLLKKLNELESDLTFKIGPEYKSMKSCLYVGMASDNVDAAELVETIAATAREIE
     540       550       560       570       580       590         

              610       620       630       640       650       660
pF1KSD ENSRLLENMTEVVRKGIQEAQVELQKASEERLLEEGVLRQIPVVGSVLNWFSPVQALQKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENSRLLENMTEVVRKGIQEAQVELQKASEERLLEEGVLRQIPVVGSVLNWFSPVQALQKG
     600       610       620       630       640       650         

              670       680       690       700       710       720
pF1KSD RTFNLTAGSLESTEPIYVYKAQGAGVTLPPTPSGSRTKQRLPGQKPFKRSLRGSDALSET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RTFNLTAGSLESTEPIYVYKAQGAGVTLPPTPSGSRTKQRLPGQKPFKRSLRGSDALSET
     660       670       680       690       700       710         

              730       740       750       760       770       780
pF1KSD SSVSHIEDLEKVERLSSGPEQITLEASSTEGHPGAPSPQHTDQTEAFQKGVPHPEDDHSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSVSHIEDLEKVERLSSGPEQITLEASSTEGHPGAPSPQHTDQTEAFQKGVPHPEDDHSQ
     720       730       740       750       760       770         

               
pF1KSD VEGPESLR
       ::::::::
NP_001 VEGPESLR
     780       

>>XP_016878549 (OMIM: 614244) PREDICTED: pyridoxal-depen  (797 aa)
 initn: 5169 init1: 5169 opt: 5169  Z-score: 5165.8  bits: 966.7 E(85289):    0
Smith-Waterman score: 5169; 99.6% identity (99.7% similar) in 786 aa overlap (3-788:12-797)

                        10        20        30        40        50 
pF1KSD          MDASLEKIADPTLAEMGKNLKEAVKMLEDSQRRTEEENGKKLISGDIPGPL
                  :: . ::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLPERSRSYFRASCKPIADPTLAEMGKNLKEAVKMLEDSQRRTEEENGKKLISGDIPGPL
               10        20        30        40        50        60

              60        70        80        90       100       110 
pF1KSD QGSGQDMVSILQLVQNLMHGDEDEEPQSPRIQNIGEQGHMALLGHSLGAYISTLDKEKLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QGSGQDMVSILQLVQNLMHGDEDEEPQSPRIQNIGEQGHMALLGHSLGAYISTLDKEKLR
               70        80        90       100       110       120

             120       130       140       150       160       170 
pF1KSD KLTTRILSDTTLWLCRIFRYENGCAYFHEEEREGLAKICRLAIHSRYEDFVVDGFNVLYN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLTTRILSDTTLWLCRIFRYENGCAYFHEEEREGLAKICRLAIHSRYEDFVVDGFNVLYN
              130       140       150       160       170       180

             180       190       200       210       220       230 
pF1KSD KKPVIYLSAAARPGLGQYLCNQLGLPFPCLCRVPCNTVFGSQHQMDVAFLEKLIKDDIER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKPVIYLSAAARPGLGQYLCNQLGLPFPCLCRVPCNTVFGSQHQMDVAFLEKLIKDDIER
              190       200       210       220       230       240

             240       250       260       270       280       290 
pF1KSD GRLPLLLVANAGTAAVGHTDKIGRLKELCEQYGIWLHVEGVNLATLALGYVSSSVLAAAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRLPLLLVANAGTAAVGHTDKIGRLKELCEQYGIWLHVEGVNLATLALGYVSSSVLAAAK
              250       260       270       280       290       300

             300       310       320       330       340       350 
pF1KSD CDSMTMTPGPWLGLPAVPAVTLYKHDDPALTLVAGLTSNKPTDKLRALPLWLSLQYLGLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CDSMTMTPGPWLGLPAVPAVTLYKHDDPALTLVAGLTSNKPTDKLRALPLWLSLQYLGLD
              310       320       330       340       350       360

             360       370       380       390       400       410 
pF1KSD GFVERIKHACQLSQRLQESLKKVNYIKILVEDELSSPVVVFRFFQELPGSDPVFKAVPVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GFVERIKHACQLSQRLQESLKKVNYIKILVEDELSSPVVVFRFFQELPGSDPVFKAVPVP
              370       380       390       400       410       420

             420       430       440       450       460       470 
pF1KSD NMTPSGVGRERHSCDALNRWLGEQLKQLVPASGLTVMDLEAEGTCLRFSPLMTAAVLGTR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NMTPSGVGRERHSCDALNRWLGEQLKQLVPASGLTVMDLEAEGTCLRFSPLMTAAVLGTR
              430       440       450       460       470       480

             480       490       500       510       520       530 
pF1KSD GEDVDQLVACIESKLPVLCCTLQLREEFKQEVEATAGLLYVDDPNWSGIGVVRYEHANDD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GEDVDQLVACIESKLPVLCCTLQLREEFKQEVEATAGLLYVDDPNWSGIGVVRYEHANDD
              490       500       510       520       530       540

             540       550       560       570       580       590 
pF1KSD KSSLKSDPEGENIHAGLLKKLNELESDLTFKIGPEYKSMKSCLYVGMASDNVDAAELVET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSSLKSDPEGENIHAGLLKKLNELESDLTFKIGPEYKSMKSCLYVGMASDNVDAAELVET
              550       560       570       580       590       600

             600       610       620       630       640       650 
pF1KSD IAATAREIEENSRLLENMTEVVRKGIQEAQVELQKASEERLLEEGVLRQIPVVGSVLNWF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IAATAREIEENSRLLENMTEVVRKGIQEAQVELQKASEERLLEEGVLRQIPVVGSVLNWF
              610       620       630       640       650       660

             660       670       680       690       700       710 
pF1KSD SPVQALQKGRTFNLTAGSLESTEPIYVYKAQGAGVTLPPTPSGSRTKQRLPGQKPFKRSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPVQALQKGRTFNLTAGSLESTEPIYVYKAQGAGVTLPPTPSGSRTKQRLPGQKPFKRSL
              670       680       690       700       710       720

             720       730       740       750       760       770 
pF1KSD RGSDALSETSSVSHIEDLEKVERLSSGPEQITLEASSTEGHPGAPSPQHTDQTEAFQKGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGSDALSETSSVSHIEDLEKVERLSSGPEQITLEASSTEGHPGAPSPQHTDQTEAFQKGV
              730       740       750       760       770       780

             780        
pF1KSD PHPEDDHSQVEGPESLR
       :::::::::::::::::
XP_016 PHPEDDHSQVEGPESLR
              790       

>>XP_005255230 (OMIM: 614244) PREDICTED: pyridoxal-depen  (806 aa)
 initn: 5162 init1: 5162 opt: 5162  Z-score: 5158.8  bits: 965.4 E(85289):    0
Smith-Waterman score: 5162; 99.9% identity (100.0% similar) in 782 aa overlap (7-788:25-806)

                                 10        20        30        40  
pF1KSD                   MDASLEKIADPTLAEMGKNLKEAVKMLEDSQRRTEEENGKKL
                               .:::::::::::::::::::::::::::::::::::
XP_005 MACSILEGCRREVRRETWKPGPGSEIADPTLAEMGKNLKEAVKMLEDSQRRTEEENGKKL
               10        20        30        40        50        60

             50        60        70        80        90       100  
pF1KSD ISGDIPGPLQGSGQDMVSILQLVQNLMHGDEDEEPQSPRIQNIGEQGHMALLGHSLGAYI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ISGDIPGPLQGSGQDMVSILQLVQNLMHGDEDEEPQSPRIQNIGEQGHMALLGHSLGAYI
               70        80        90       100       110       120

            110       120       130       140       150       160  
pF1KSD STLDKEKLRKLTTRILSDTTLWLCRIFRYENGCAYFHEEEREGLAKICRLAIHSRYEDFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 STLDKEKLRKLTTRILSDTTLWLCRIFRYENGCAYFHEEEREGLAKICRLAIHSRYEDFV
              130       140       150       160       170       180

            170       180       190       200       210       220  
pF1KSD VDGFNVLYNKKPVIYLSAAARPGLGQYLCNQLGLPFPCLCRVPCNTVFGSQHQMDVAFLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VDGFNVLYNKKPVIYLSAAARPGLGQYLCNQLGLPFPCLCRVPCNTVFGSQHQMDVAFLE
              190       200       210       220       230       240

            230       240       250       260       270       280  
pF1KSD KLIKDDIERGRLPLLLVANAGTAAVGHTDKIGRLKELCEQYGIWLHVEGVNLATLALGYV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KLIKDDIERGRLPLLLVANAGTAAVGHTDKIGRLKELCEQYGIWLHVEGVNLATLALGYV
              250       260       270       280       290       300

            290       300       310       320       330       340  
pF1KSD SSSVLAAAKCDSMTMTPGPWLGLPAVPAVTLYKHDDPALTLVAGLTSNKPTDKLRALPLW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSSVLAAAKCDSMTMTPGPWLGLPAVPAVTLYKHDDPALTLVAGLTSNKPTDKLRALPLW
              310       320       330       340       350       360

            350       360       370       380       390       400  
pF1KSD LSLQYLGLDGFVERIKHACQLSQRLQESLKKVNYIKILVEDELSSPVVVFRFFQELPGSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LSLQYLGLDGFVERIKHACQLSQRLQESLKKVNYIKILVEDELSSPVVVFRFFQELPGSD
              370       380       390       400       410       420

            410       420       430       440       450       460  
pF1KSD PVFKAVPVPNMTPSGVGRERHSCDALNRWLGEQLKQLVPASGLTVMDLEAEGTCLRFSPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PVFKAVPVPNMTPSGVGRERHSCDALNRWLGEQLKQLVPASGLTVMDLEAEGTCLRFSPL
              430       440       450       460       470       480

            470       480       490       500       510       520  
pF1KSD MTAAVLGTRGEDVDQLVACIESKLPVLCCTLQLREEFKQEVEATAGLLYVDDPNWSGIGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MTAAVLGTRGEDVDQLVACIESKLPVLCCTLQLREEFKQEVEATAGLLYVDDPNWSGIGV
              490       500       510       520       530       540

            530       540       550       560       570       580  
pF1KSD VRYEHANDDKSSLKSDPEGENIHAGLLKKLNELESDLTFKIGPEYKSMKSCLYVGMASDN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VRYEHANDDKSSLKSDPEGENIHAGLLKKLNELESDLTFKIGPEYKSMKSCLYVGMASDN
              550       560       570       580       590       600

            590       600       610       620       630       640  
pF1KSD VDAAELVETIAATAREIEENSRLLENMTEVVRKGIQEAQVELQKASEERLLEEGVLRQIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VDAAELVETIAATAREIEENSRLLENMTEVVRKGIQEAQVELQKASEERLLEEGVLRQIP
              610       620       630       640       650       660

            650       660       670       680       690       700  
pF1KSD VVGSVLNWFSPVQALQKGRTFNLTAGSLESTEPIYVYKAQGAGVTLPPTPSGSRTKQRLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VVGSVLNWFSPVQALQKGRTFNLTAGSLESTEPIYVYKAQGAGVTLPPTPSGSRTKQRLP
              670       680       690       700       710       720

            710       720       730       740       750       760  
pF1KSD GQKPFKRSLRGSDALSETSSVSHIEDLEKVERLSSGPEQITLEASSTEGHPGAPSPQHTD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GQKPFKRSLRGSDALSETSSVSHIEDLEKVERLSSGPEQITLEASSTEGHPGAPSPQHTD
              730       740       750       760       770       780

            770       780        
pF1KSD QTEAFQKGVPHPEDDHSQVEGPESLR
       ::::::::::::::::::::::::::
XP_005 QTEAFQKGVPHPEDDHSQVEGPESLR
              790       800      

>>XP_016878548 (OMIM: 614244) PREDICTED: pyridoxal-depen  (773 aa)
 initn: 5112 init1: 5112 opt: 5112  Z-score: 5109.1  bits: 956.1 E(85289):    0
Smith-Waterman score: 5112; 100.0% identity (100.0% similar) in 773 aa overlap (16-788:1-773)

               10        20        30        40        50        60
pF1KSD MDASLEKIADPTLAEMGKNLKEAVKMLEDSQRRTEEENGKKLISGDIPGPLQGSGQDMVS
                      :::::::::::::::::::::::::::::::::::::::::::::
XP_016                MGKNLKEAVKMLEDSQRRTEEENGKKLISGDIPGPLQGSGQDMVS
                              10        20        30        40     

               70        80        90       100       110       120
pF1KSD ILQLVQNLMHGDEDEEPQSPRIQNIGEQGHMALLGHSLGAYISTLDKEKLRKLTTRILSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILQLVQNLMHGDEDEEPQSPRIQNIGEQGHMALLGHSLGAYISTLDKEKLRKLTTRILSD
          50        60        70        80        90       100     

              130       140       150       160       170       180
pF1KSD TTLWLCRIFRYENGCAYFHEEEREGLAKICRLAIHSRYEDFVVDGFNVLYNKKPVIYLSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TTLWLCRIFRYENGCAYFHEEEREGLAKICRLAIHSRYEDFVVDGFNVLYNKKPVIYLSA
         110       120       130       140       150       160     

              190       200       210       220       230       240
pF1KSD AARPGLGQYLCNQLGLPFPCLCRVPCNTVFGSQHQMDVAFLEKLIKDDIERGRLPLLLVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AARPGLGQYLCNQLGLPFPCLCRVPCNTVFGSQHQMDVAFLEKLIKDDIERGRLPLLLVA
         170       180       190       200       210       220     

              250       260       270       280       290       300
pF1KSD NAGTAAVGHTDKIGRLKELCEQYGIWLHVEGVNLATLALGYVSSSVLAAAKCDSMTMTPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NAGTAAVGHTDKIGRLKELCEQYGIWLHVEGVNLATLALGYVSSSVLAAAKCDSMTMTPG
         230       240       250       260       270       280     

              310       320       330       340       350       360
pF1KSD PWLGLPAVPAVTLYKHDDPALTLVAGLTSNKPTDKLRALPLWLSLQYLGLDGFVERIKHA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PWLGLPAVPAVTLYKHDDPALTLVAGLTSNKPTDKLRALPLWLSLQYLGLDGFVERIKHA
         290       300       310       320       330       340     

              370       380       390       400       410       420
pF1KSD CQLSQRLQESLKKVNYIKILVEDELSSPVVVFRFFQELPGSDPVFKAVPVPNMTPSGVGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CQLSQRLQESLKKVNYIKILVEDELSSPVVVFRFFQELPGSDPVFKAVPVPNMTPSGVGR
         350       360       370       380       390       400     

              430       440       450       460       470       480
pF1KSD ERHSCDALNRWLGEQLKQLVPASGLTVMDLEAEGTCLRFSPLMTAAVLGTRGEDVDQLVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERHSCDALNRWLGEQLKQLVPASGLTVMDLEAEGTCLRFSPLMTAAVLGTRGEDVDQLVA
         410       420       430       440       450       460     

              490       500       510       520       530       540
pF1KSD CIESKLPVLCCTLQLREEFKQEVEATAGLLYVDDPNWSGIGVVRYEHANDDKSSLKSDPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CIESKLPVLCCTLQLREEFKQEVEATAGLLYVDDPNWSGIGVVRYEHANDDKSSLKSDPE
         470       480       490       500       510       520     

              550       560       570       580       590       600
pF1KSD GENIHAGLLKKLNELESDLTFKIGPEYKSMKSCLYVGMASDNVDAAELVETIAATAREIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GENIHAGLLKKLNELESDLTFKIGPEYKSMKSCLYVGMASDNVDAAELVETIAATAREIE
         530       540       550       560       570       580     

              610       620       630       640       650       660
pF1KSD ENSRLLENMTEVVRKGIQEAQVELQKASEERLLEEGVLRQIPVVGSVLNWFSPVQALQKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENSRLLENMTEVVRKGIQEAQVELQKASEERLLEEGVLRQIPVVGSVLNWFSPVQALQKG
         590       600       610       620       630       640     

              670       680       690       700       710       720
pF1KSD RTFNLTAGSLESTEPIYVYKAQGAGVTLPPTPSGSRTKQRLPGQKPFKRSLRGSDALSET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTFNLTAGSLESTEPIYVYKAQGAGVTLPPTPSGSRTKQRLPGQKPFKRSLRGSDALSET
         650       660       670       680       690       700     

              730       740       750       760       770       780
pF1KSD SSVSHIEDLEKVERLSSGPEQITLEASSTEGHPGAPSPQHTDQTEAFQKGVPHPEDDHSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSVSHIEDLEKVERLSSGPEQITLEASSTEGHPGAPSPQHTDQTEAFQKGVPHPEDDHSQ
         710       720       730       740       750       760     

               
pF1KSD VEGPESLR
       ::::::::
XP_016 VEGPESLR
         770   

>>XP_005255233 (OMIM: 614244) PREDICTED: pyridoxal-depen  (773 aa)
 initn: 5112 init1: 5112 opt: 5112  Z-score: 5109.1  bits: 956.1 E(85289):    0
Smith-Waterman score: 5112; 100.0% identity (100.0% similar) in 773 aa overlap (16-788:1-773)

               10        20        30        40        50        60
pF1KSD MDASLEKIADPTLAEMGKNLKEAVKMLEDSQRRTEEENGKKLISGDIPGPLQGSGQDMVS
                      :::::::::::::::::::::::::::::::::::::::::::::
XP_005                MGKNLKEAVKMLEDSQRRTEEENGKKLISGDIPGPLQGSGQDMVS
                              10        20        30        40     

               70        80        90       100       110       120
pF1KSD ILQLVQNLMHGDEDEEPQSPRIQNIGEQGHMALLGHSLGAYISTLDKEKLRKLTTRILSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ILQLVQNLMHGDEDEEPQSPRIQNIGEQGHMALLGHSLGAYISTLDKEKLRKLTTRILSD
          50        60        70        80        90       100     

              130       140       150       160       170       180
pF1KSD TTLWLCRIFRYENGCAYFHEEEREGLAKICRLAIHSRYEDFVVDGFNVLYNKKPVIYLSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TTLWLCRIFRYENGCAYFHEEEREGLAKICRLAIHSRYEDFVVDGFNVLYNKKPVIYLSA
         110       120       130       140       150       160     

              190       200       210       220       230       240
pF1KSD AARPGLGQYLCNQLGLPFPCLCRVPCNTVFGSQHQMDVAFLEKLIKDDIERGRLPLLLVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AARPGLGQYLCNQLGLPFPCLCRVPCNTVFGSQHQMDVAFLEKLIKDDIERGRLPLLLVA
         170       180       190       200       210       220     

              250       260       270       280       290       300
pF1KSD NAGTAAVGHTDKIGRLKELCEQYGIWLHVEGVNLATLALGYVSSSVLAAAKCDSMTMTPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NAGTAAVGHTDKIGRLKELCEQYGIWLHVEGVNLATLALGYVSSSVLAAAKCDSMTMTPG
         230       240       250       260       270       280     

              310       320       330       340       350       360
pF1KSD PWLGLPAVPAVTLYKHDDPALTLVAGLTSNKPTDKLRALPLWLSLQYLGLDGFVERIKHA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PWLGLPAVPAVTLYKHDDPALTLVAGLTSNKPTDKLRALPLWLSLQYLGLDGFVERIKHA
         290       300       310       320       330       340     

              370       380       390       400       410       420
pF1KSD CQLSQRLQESLKKVNYIKILVEDELSSPVVVFRFFQELPGSDPVFKAVPVPNMTPSGVGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CQLSQRLQESLKKVNYIKILVEDELSSPVVVFRFFQELPGSDPVFKAVPVPNMTPSGVGR
         350       360       370       380       390       400     

              430       440       450       460       470       480
pF1KSD ERHSCDALNRWLGEQLKQLVPASGLTVMDLEAEGTCLRFSPLMTAAVLGTRGEDVDQLVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ERHSCDALNRWLGEQLKQLVPASGLTVMDLEAEGTCLRFSPLMTAAVLGTRGEDVDQLVA
         410       420       430       440       450       460     

              490       500       510       520       530       540
pF1KSD CIESKLPVLCCTLQLREEFKQEVEATAGLLYVDDPNWSGIGVVRYEHANDDKSSLKSDPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CIESKLPVLCCTLQLREEFKQEVEATAGLLYVDDPNWSGIGVVRYEHANDDKSSLKSDPE
         470       480       490       500       510       520     

              550       560       570       580       590       600
pF1KSD GENIHAGLLKKLNELESDLTFKIGPEYKSMKSCLYVGMASDNVDAAELVETIAATAREIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GENIHAGLLKKLNELESDLTFKIGPEYKSMKSCLYVGMASDNVDAAELVETIAATAREIE
         530       540       550       560       570       580     

              610       620       630       640       650       660
pF1KSD ENSRLLENMTEVVRKGIQEAQVELQKASEERLLEEGVLRQIPVVGSVLNWFSPVQALQKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ENSRLLENMTEVVRKGIQEAQVELQKASEERLLEEGVLRQIPVVGSVLNWFSPVQALQKG
         590       600       610       620       630       640     

              670       680       690       700       710       720
pF1KSD RTFNLTAGSLESTEPIYVYKAQGAGVTLPPTPSGSRTKQRLPGQKPFKRSLRGSDALSET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RTFNLTAGSLESTEPIYVYKAQGAGVTLPPTPSGSRTKQRLPGQKPFKRSLRGSDALSET
         650       660       670       680       690       700     

              730       740       750       760       770       780
pF1KSD SSVSHIEDLEKVERLSSGPEQITLEASSTEGHPGAPSPQHTDQTEAFQKGVPHPEDDHSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSVSHIEDLEKVERLSSGPEQITLEASSTEGHPGAPSPQHTDQTEAFQKGVPHPEDDHSQ
         710       720       730       740       750       760     

               
pF1KSD VEGPESLR
       ::::::::
XP_005 VEGPESLR
         770   

>>XP_016878550 (OMIM: 614244) PREDICTED: pyridoxal-depen  (773 aa)
 initn: 5112 init1: 5112 opt: 5112  Z-score: 5109.1  bits: 956.1 E(85289):    0
Smith-Waterman score: 5112; 100.0% identity (100.0% similar) in 773 aa overlap (16-788:1-773)

               10        20        30        40        50        60
pF1KSD MDASLEKIADPTLAEMGKNLKEAVKMLEDSQRRTEEENGKKLISGDIPGPLQGSGQDMVS
                      :::::::::::::::::::::::::::::::::::::::::::::
XP_016                MGKNLKEAVKMLEDSQRRTEEENGKKLISGDIPGPLQGSGQDMVS
                              10        20        30        40     

               70        80        90       100       110       120
pF1KSD ILQLVQNLMHGDEDEEPQSPRIQNIGEQGHMALLGHSLGAYISTLDKEKLRKLTTRILSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILQLVQNLMHGDEDEEPQSPRIQNIGEQGHMALLGHSLGAYISTLDKEKLRKLTTRILSD
          50        60        70        80        90       100     

              130       140       150       160       170       180
pF1KSD TTLWLCRIFRYENGCAYFHEEEREGLAKICRLAIHSRYEDFVVDGFNVLYNKKPVIYLSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TTLWLCRIFRYENGCAYFHEEEREGLAKICRLAIHSRYEDFVVDGFNVLYNKKPVIYLSA
         110       120       130       140       150       160     

              190       200       210       220       230       240
pF1KSD AARPGLGQYLCNQLGLPFPCLCRVPCNTVFGSQHQMDVAFLEKLIKDDIERGRLPLLLVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AARPGLGQYLCNQLGLPFPCLCRVPCNTVFGSQHQMDVAFLEKLIKDDIERGRLPLLLVA
         170       180       190       200       210       220     

              250       260       270       280       290       300
pF1KSD NAGTAAVGHTDKIGRLKELCEQYGIWLHVEGVNLATLALGYVSSSVLAAAKCDSMTMTPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NAGTAAVGHTDKIGRLKELCEQYGIWLHVEGVNLATLALGYVSSSVLAAAKCDSMTMTPG
         230       240       250       260       270       280     

              310       320       330       340       350       360
pF1KSD PWLGLPAVPAVTLYKHDDPALTLVAGLTSNKPTDKLRALPLWLSLQYLGLDGFVERIKHA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PWLGLPAVPAVTLYKHDDPALTLVAGLTSNKPTDKLRALPLWLSLQYLGLDGFVERIKHA
         290       300       310       320       330       340     

              370       380       390       400       410       420
pF1KSD CQLSQRLQESLKKVNYIKILVEDELSSPVVVFRFFQELPGSDPVFKAVPVPNMTPSGVGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CQLSQRLQESLKKVNYIKILVEDELSSPVVVFRFFQELPGSDPVFKAVPVPNMTPSGVGR
         350       360       370       380       390       400     

              430       440       450       460       470       480
pF1KSD ERHSCDALNRWLGEQLKQLVPASGLTVMDLEAEGTCLRFSPLMTAAVLGTRGEDVDQLVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERHSCDALNRWLGEQLKQLVPASGLTVMDLEAEGTCLRFSPLMTAAVLGTRGEDVDQLVA
         410       420       430       440       450       460     

              490       500       510       520       530       540
pF1KSD CIESKLPVLCCTLQLREEFKQEVEATAGLLYVDDPNWSGIGVVRYEHANDDKSSLKSDPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CIESKLPVLCCTLQLREEFKQEVEATAGLLYVDDPNWSGIGVVRYEHANDDKSSLKSDPE
         470       480       490       500       510       520     

              550       560       570       580       590       600
pF1KSD GENIHAGLLKKLNELESDLTFKIGPEYKSMKSCLYVGMASDNVDAAELVETIAATAREIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GENIHAGLLKKLNELESDLTFKIGPEYKSMKSCLYVGMASDNVDAAELVETIAATAREIE
         530       540       550       560       570       580     

              610       620       630       640       650       660
pF1KSD ENSRLLENMTEVVRKGIQEAQVELQKASEERLLEEGVLRQIPVVGSVLNWFSPVQALQKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENSRLLENMTEVVRKGIQEAQVELQKASEERLLEEGVLRQIPVVGSVLNWFSPVQALQKG
         590       600       610       620       630       640     

              670       680       690       700       710       720
pF1KSD RTFNLTAGSLESTEPIYVYKAQGAGVTLPPTPSGSRTKQRLPGQKPFKRSLRGSDALSET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTFNLTAGSLESTEPIYVYKAQGAGVTLPPTPSGSRTKQRLPGQKPFKRSLRGSDALSET
         650       660       670       680       690       700     

              730       740       750       760       770       780
pF1KSD SSVSHIEDLEKVERLSSGPEQITLEASSTEGHPGAPSPQHTDQTEAFQKGVPHPEDDHSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSVSHIEDLEKVERLSSGPEQITLEASSTEGHPGAPSPQHTDQTEAFQKGVPHPEDDHSQ
         710       720       730       740       750       760     

               
pF1KSD VEGPESLR
       ::::::::
XP_016 VEGPESLR
         770   

>>NP_001272376 (OMIM: 614244) pyridoxal-dependent decarb  (773 aa)
 initn: 5112 init1: 5112 opt: 5112  Z-score: 5109.1  bits: 956.1 E(85289):    0
Smith-Waterman score: 5112; 100.0% identity (100.0% similar) in 773 aa overlap (16-788:1-773)

               10        20        30        40        50        60
pF1KSD MDASLEKIADPTLAEMGKNLKEAVKMLEDSQRRTEEENGKKLISGDIPGPLQGSGQDMVS
                      :::::::::::::::::::::::::::::::::::::::::::::
NP_001                MGKNLKEAVKMLEDSQRRTEEENGKKLISGDIPGPLQGSGQDMVS
                              10        20        30        40     

               70        80        90       100       110       120
pF1KSD ILQLVQNLMHGDEDEEPQSPRIQNIGEQGHMALLGHSLGAYISTLDKEKLRKLTTRILSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILQLVQNLMHGDEDEEPQSPRIQNIGEQGHMALLGHSLGAYISTLDKEKLRKLTTRILSD
          50        60        70        80        90       100     

              130       140       150       160       170       180
pF1KSD TTLWLCRIFRYENGCAYFHEEEREGLAKICRLAIHSRYEDFVVDGFNVLYNKKPVIYLSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTLWLCRIFRYENGCAYFHEEEREGLAKICRLAIHSRYEDFVVDGFNVLYNKKPVIYLSA
         110       120       130       140       150       160     

              190       200       210       220       230       240
pF1KSD AARPGLGQYLCNQLGLPFPCLCRVPCNTVFGSQHQMDVAFLEKLIKDDIERGRLPLLLVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AARPGLGQYLCNQLGLPFPCLCRVPCNTVFGSQHQMDVAFLEKLIKDDIERGRLPLLLVA
         170       180       190       200       210       220     

              250       260       270       280       290       300
pF1KSD NAGTAAVGHTDKIGRLKELCEQYGIWLHVEGVNLATLALGYVSSSVLAAAKCDSMTMTPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NAGTAAVGHTDKIGRLKELCEQYGIWLHVEGVNLATLALGYVSSSVLAAAKCDSMTMTPG
         230       240       250       260       270       280     

              310       320       330       340       350       360
pF1KSD PWLGLPAVPAVTLYKHDDPALTLVAGLTSNKPTDKLRALPLWLSLQYLGLDGFVERIKHA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PWLGLPAVPAVTLYKHDDPALTLVAGLTSNKPTDKLRALPLWLSLQYLGLDGFVERIKHA
         290       300       310       320       330       340     

              370       380       390       400       410       420
pF1KSD CQLSQRLQESLKKVNYIKILVEDELSSPVVVFRFFQELPGSDPVFKAVPVPNMTPSGVGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CQLSQRLQESLKKVNYIKILVEDELSSPVVVFRFFQELPGSDPVFKAVPVPNMTPSGVGR
         350       360       370       380       390       400     

              430       440       450       460       470       480
pF1KSD ERHSCDALNRWLGEQLKQLVPASGLTVMDLEAEGTCLRFSPLMTAAVLGTRGEDVDQLVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERHSCDALNRWLGEQLKQLVPASGLTVMDLEAEGTCLRFSPLMTAAVLGTRGEDVDQLVA
         410       420       430       440       450       460     

              490       500       510       520       530       540
pF1KSD CIESKLPVLCCTLQLREEFKQEVEATAGLLYVDDPNWSGIGVVRYEHANDDKSSLKSDPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CIESKLPVLCCTLQLREEFKQEVEATAGLLYVDDPNWSGIGVVRYEHANDDKSSLKSDPE
         470       480       490       500       510       520     

              550       560       570       580       590       600
pF1KSD GENIHAGLLKKLNELESDLTFKIGPEYKSMKSCLYVGMASDNVDAAELVETIAATAREIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GENIHAGLLKKLNELESDLTFKIGPEYKSMKSCLYVGMASDNVDAAELVETIAATAREIE
         530       540       550       560       570       580     

              610       620       630       640       650       660
pF1KSD ENSRLLENMTEVVRKGIQEAQVELQKASEERLLEEGVLRQIPVVGSVLNWFSPVQALQKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENSRLLENMTEVVRKGIQEAQVELQKASEERLLEEGVLRQIPVVGSVLNWFSPVQALQKG
         590       600       610       620       630       640     

              670       680       690       700       710       720
pF1KSD RTFNLTAGSLESTEPIYVYKAQGAGVTLPPTPSGSRTKQRLPGQKPFKRSLRGSDALSET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RTFNLTAGSLESTEPIYVYKAQGAGVTLPPTPSGSRTKQRLPGQKPFKRSLRGSDALSET
         650       660       670       680       690       700     

              730       740       750       760       770       780
pF1KSD SSVSHIEDLEKVERLSSGPEQITLEASSTEGHPGAPSPQHTDQTEAFQKGVPHPEDDHSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSVSHIEDLEKVERLSSGPEQITLEASSTEGHPGAPSPQHTDQTEAFQKGVPHPEDDHSQ
         710       720       730       740       750       760     

               
pF1KSD VEGPESLR
       ::::::::
NP_001 VEGPESLR
         770   

>>XP_016878551 (OMIM: 614244) PREDICTED: pyridoxal-depen  (773 aa)
 initn: 5112 init1: 5112 opt: 5112  Z-score: 5109.1  bits: 956.1 E(85289):    0
Smith-Waterman score: 5112; 100.0% identity (100.0% similar) in 773 aa overlap (16-788:1-773)

               10        20        30        40        50        60
pF1KSD MDASLEKIADPTLAEMGKNLKEAVKMLEDSQRRTEEENGKKLISGDIPGPLQGSGQDMVS
                      :::::::::::::::::::::::::::::::::::::::::::::
XP_016                MGKNLKEAVKMLEDSQRRTEEENGKKLISGDIPGPLQGSGQDMVS
                              10        20        30        40     

               70        80        90       100       110       120
pF1KSD ILQLVQNLMHGDEDEEPQSPRIQNIGEQGHMALLGHSLGAYISTLDKEKLRKLTTRILSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILQLVQNLMHGDEDEEPQSPRIQNIGEQGHMALLGHSLGAYISTLDKEKLRKLTTRILSD
          50        60        70        80        90       100     

              130       140       150       160       170       180
pF1KSD TTLWLCRIFRYENGCAYFHEEEREGLAKICRLAIHSRYEDFVVDGFNVLYNKKPVIYLSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TTLWLCRIFRYENGCAYFHEEEREGLAKICRLAIHSRYEDFVVDGFNVLYNKKPVIYLSA
         110       120       130       140       150       160     

              190       200       210       220       230       240
pF1KSD AARPGLGQYLCNQLGLPFPCLCRVPCNTVFGSQHQMDVAFLEKLIKDDIERGRLPLLLVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AARPGLGQYLCNQLGLPFPCLCRVPCNTVFGSQHQMDVAFLEKLIKDDIERGRLPLLLVA
         170       180       190       200       210       220     

              250       260       270       280       290       300
pF1KSD NAGTAAVGHTDKIGRLKELCEQYGIWLHVEGVNLATLALGYVSSSVLAAAKCDSMTMTPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NAGTAAVGHTDKIGRLKELCEQYGIWLHVEGVNLATLALGYVSSSVLAAAKCDSMTMTPG
         230       240       250       260       270       280     

              310       320       330       340       350       360
pF1KSD PWLGLPAVPAVTLYKHDDPALTLVAGLTSNKPTDKLRALPLWLSLQYLGLDGFVERIKHA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PWLGLPAVPAVTLYKHDDPALTLVAGLTSNKPTDKLRALPLWLSLQYLGLDGFVERIKHA
         290       300       310       320       330       340     

              370       380       390       400       410       420
pF1KSD CQLSQRLQESLKKVNYIKILVEDELSSPVVVFRFFQELPGSDPVFKAVPVPNMTPSGVGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CQLSQRLQESLKKVNYIKILVEDELSSPVVVFRFFQELPGSDPVFKAVPVPNMTPSGVGR
         350       360       370       380       390       400     

              430       440       450       460       470       480
pF1KSD ERHSCDALNRWLGEQLKQLVPASGLTVMDLEAEGTCLRFSPLMTAAVLGTRGEDVDQLVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERHSCDALNRWLGEQLKQLVPASGLTVMDLEAEGTCLRFSPLMTAAVLGTRGEDVDQLVA
         410       420       430       440       450       460     

              490       500       510       520       530       540
pF1KSD CIESKLPVLCCTLQLREEFKQEVEATAGLLYVDDPNWSGIGVVRYEHANDDKSSLKSDPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CIESKLPVLCCTLQLREEFKQEVEATAGLLYVDDPNWSGIGVVRYEHANDDKSSLKSDPE
         470       480       490       500       510       520     

              550       560       570       580       590       600
pF1KSD GENIHAGLLKKLNELESDLTFKIGPEYKSMKSCLYVGMASDNVDAAELVETIAATAREIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GENIHAGLLKKLNELESDLTFKIGPEYKSMKSCLYVGMASDNVDAAELVETIAATAREIE
         530       540       550       560       570       580     

              610       620       630       640       650       660
pF1KSD ENSRLLENMTEVVRKGIQEAQVELQKASEERLLEEGVLRQIPVVGSVLNWFSPVQALQKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENSRLLENMTEVVRKGIQEAQVELQKASEERLLEEGVLRQIPVVGSVLNWFSPVQALQKG
         590       600       610       620       630       640     

              670       680       690       700       710       720
pF1KSD RTFNLTAGSLESTEPIYVYKAQGAGVTLPPTPSGSRTKQRLPGQKPFKRSLRGSDALSET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTFNLTAGSLESTEPIYVYKAQGAGVTLPPTPSGSRTKQRLPGQKPFKRSLRGSDALSET
         650       660       670       680       690       700     

              730       740       750       760       770       780
pF1KSD SSVSHIEDLEKVERLSSGPEQITLEASSTEGHPGAPSPQHTDQTEAFQKGVPHPEDDHSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSVSHIEDLEKVERLSSGPEQITLEASSTEGHPGAPSPQHTDQTEAFQKGVPHPEDDHSQ
         710       720       730       740       750       760     

               
pF1KSD VEGPESLR
       ::::::::
XP_016 VEGPESLR
         770   

>>XP_016878553 (OMIM: 614244) PREDICTED: pyridoxal-depen  (746 aa)
 initn: 4689 init1: 4689 opt: 4693  Z-score: 4690.6  bits: 878.7 E(85289):    0
Smith-Waterman score: 4866; 96.5% identity (96.5% similar) in 773 aa overlap (16-788:1-746)

               10        20        30        40        50        60
pF1KSD MDASLEKIADPTLAEMGKNLKEAVKMLEDSQRRTEEENGKKLISGDIPGPLQGSGQDMVS
                      ::::::::::::::::::::::::::::::::::::::       
XP_016                MGKNLKEAVKMLEDSQRRTEEENGKKLISGDIPGPLQG-------
                              10        20        30               

               70        80        90       100       110       120
pF1KSD ILQLVQNLMHGDEDEEPQSPRIQNIGEQGHMALLGHSLGAYISTLDKEKLRKLTTRILSD
                           ::::::::::::::::::::::::::::::::::::::::
XP_016 --------------------RIQNIGEQGHMALLGHSLGAYISTLDKEKLRKLTTRILSD
                           40        50        60        70        

              130       140       150       160       170       180
pF1KSD TTLWLCRIFRYENGCAYFHEEEREGLAKICRLAIHSRYEDFVVDGFNVLYNKKPVIYLSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TTLWLCRIFRYENGCAYFHEEEREGLAKICRLAIHSRYEDFVVDGFNVLYNKKPVIYLSA
       80        90       100       110       120       130        

              190       200       210       220       230       240
pF1KSD AARPGLGQYLCNQLGLPFPCLCRVPCNTVFGSQHQMDVAFLEKLIKDDIERGRLPLLLVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AARPGLGQYLCNQLGLPFPCLCRVPCNTVFGSQHQMDVAFLEKLIKDDIERGRLPLLLVA
      140       150       160       170       180       190        

              250       260       270       280       290       300
pF1KSD NAGTAAVGHTDKIGRLKELCEQYGIWLHVEGVNLATLALGYVSSSVLAAAKCDSMTMTPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NAGTAAVGHTDKIGRLKELCEQYGIWLHVEGVNLATLALGYVSSSVLAAAKCDSMTMTPG
      200       210       220       230       240       250        

              310       320       330       340       350       360
pF1KSD PWLGLPAVPAVTLYKHDDPALTLVAGLTSNKPTDKLRALPLWLSLQYLGLDGFVERIKHA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PWLGLPAVPAVTLYKHDDPALTLVAGLTSNKPTDKLRALPLWLSLQYLGLDGFVERIKHA
      260       270       280       290       300       310        

              370       380       390       400       410       420
pF1KSD CQLSQRLQESLKKVNYIKILVEDELSSPVVVFRFFQELPGSDPVFKAVPVPNMTPSGVGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CQLSQRLQESLKKVNYIKILVEDELSSPVVVFRFFQELPGSDPVFKAVPVPNMTPSGVGR
      320       330       340       350       360       370        

              430       440       450       460       470       480
pF1KSD ERHSCDALNRWLGEQLKQLVPASGLTVMDLEAEGTCLRFSPLMTAAVLGTRGEDVDQLVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERHSCDALNRWLGEQLKQLVPASGLTVMDLEAEGTCLRFSPLMTAAVLGTRGEDVDQLVA
      380       390       400       410       420       430        

              490       500       510       520       530       540
pF1KSD CIESKLPVLCCTLQLREEFKQEVEATAGLLYVDDPNWSGIGVVRYEHANDDKSSLKSDPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CIESKLPVLCCTLQLREEFKQEVEATAGLLYVDDPNWSGIGVVRYEHANDDKSSLKSDPE
      440       450       460       470       480       490        

              550       560       570       580       590       600
pF1KSD GENIHAGLLKKLNELESDLTFKIGPEYKSMKSCLYVGMASDNVDAAELVETIAATAREIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GENIHAGLLKKLNELESDLTFKIGPEYKSMKSCLYVGMASDNVDAAELVETIAATAREIE
      500       510       520       530       540       550        

              610       620       630       640       650       660
pF1KSD ENSRLLENMTEVVRKGIQEAQVELQKASEERLLEEGVLRQIPVVGSVLNWFSPVQALQKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENSRLLENMTEVVRKGIQEAQVELQKASEERLLEEGVLRQIPVVGSVLNWFSPVQALQKG
      560       570       580       590       600       610        

              670       680       690       700       710       720
pF1KSD RTFNLTAGSLESTEPIYVYKAQGAGVTLPPTPSGSRTKQRLPGQKPFKRSLRGSDALSET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTFNLTAGSLESTEPIYVYKAQGAGVTLPPTPSGSRTKQRLPGQKPFKRSLRGSDALSET
      620       630       640       650       660       670        

              730       740       750       760       770       780
pF1KSD SSVSHIEDLEKVERLSSGPEQITLEASSTEGHPGAPSPQHTDQTEAFQKGVPHPEDDHSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSVSHIEDLEKVERLSSGPEQITLEASSTEGHPGAPSPQHTDQTEAFQKGVPHPEDDHSQ
      680       690       700       710       720       730        

               
pF1KSD VEGPESLR
       ::::::::
XP_016 VEGPESLR
      740      




788 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 00:55:57 2016 done: Thu Nov  3 00:55:59 2016
 Total Scan time: 12.950 Total Display time:  0.260

Function used was FASTA [36.3.4 Apr, 2011]
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