Result of FASTA (omim) for pF1KSDA0224
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KSDA0224, 1227 aa
  1>>>pF1KSDA0224 1227 - 1227 aa - 1227 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 8.5297+/-0.000492; mu= 8.5578+/- 0.031
 mean_var=284.6710+/-57.721, 0's: 0 Z-trim(116.5): 197  B-trim: 126 in 1/56
 Lambda= 0.076016
 statistics sampled from 27474 (27686) to 27474 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.65), E-opt: 0.2 (0.325), width:  16
 Scan time: 14.540

The best scores are:                                      opt bits E(85289)
XP_011521786 (OMIM: 605584) PREDICTED: pre-mRNA-sp (1227) 8205 915.2       0
NP_054722 (OMIM: 605584) pre-mRNA-splicing factor  (1227) 8205 915.2       0
XP_011521787 (OMIM: 605584) PREDICTED: pre-mRNA-sp (1227) 8205 915.2       0
XP_005256326 (OMIM: 605584) PREDICTED: pre-mRNA-sp (1192) 6892 771.2       0
XP_016879402 (OMIM: 605584) PREDICTED: pre-mRNA-sp (1192) 6892 771.2       0
NP_001309146 (OMIM: 600396) ATP-dependent RNA heli (1129) 2545 294.4 2.7e-78
NP_004932 (OMIM: 600396) ATP-dependent RNA helicas (1220) 2545 294.5 2.9e-78
NP_001309150 (OMIM: 600396) ATP-dependent RNA heli (1218) 2537 293.6 5.3e-78
NP_001309145 (OMIM: 600396) ATP-dependent RNA heli ( 945) 2481 287.3 3.1e-76
NP_001309148 (OMIM: 600396) ATP-dependent RNA heli (1169) 2374 275.7 1.2e-72
NP_001289552 (OMIM: 600396) ATP-dependent RNA heli (1181) 2374 275.7 1.2e-72
NP_001309149 (OMIM: 600396) ATP-dependent RNA heli (1152) 2371 275.4 1.5e-72
NP_001309147 (OMIM: 600396) ATP-dependent RNA heli (1179) 2366 274.8 2.3e-72
NP_001157711 (OMIM: 603405) putative pre-mRNA-spli ( 981) 2338 271.7 1.7e-71
NP_003578 (OMIM: 603405) putative pre-mRNA-splicin (1041) 2331 270.9   3e-71
XP_011513241 (OMIM: 603405) PREDICTED: putative pr ( 742) 2316 269.1 7.5e-71
XP_011513240 (OMIM: 603405) PREDICTED: putative pr ( 742) 2316 269.1 7.5e-71
NP_001349 (OMIM: 603403) pre-mRNA-splicing factor  ( 795) 1856 218.7 1.2e-55
XP_011513242 (OMIM: 603405) PREDICTED: putative pr ( 560) 1768 208.9 7.7e-53
XP_011513243 (OMIM: 603405) PREDICTED: putative pr ( 524) 1764 208.4   1e-52
NP_001186628 (OMIM: 614405) putative ATP-dependent ( 534) 1283 155.7 7.7e-37
NP_064547 (OMIM: 614405) putative ATP-dependent RN ( 707) 1257 153.0 6.7e-36
XP_011525852 (OMIM: 615475) PREDICTED: probable AT (1143) 1155 142.0 2.1e-32
XP_005259500 (OMIM: 615475) PREDICTED: probable AT (1143) 1155 142.0 2.1e-32
XP_011525853 (OMIM: 615475) PREDICTED: probable AT (1143) 1155 142.0 2.1e-32
NP_055496 (OMIM: 615475) probable ATP-dependent RN (1143) 1155 142.0 2.1e-32
XP_016871893 (OMIM: 607960) PREDICTED: putative pr ( 743) 1100 135.8   1e-30
NP_060650 (OMIM: 607960) putative pre-mRNA-splicin ( 743) 1100 135.8   1e-30
XP_016871894 (OMIM: 607960) PREDICTED: putative pr ( 743) 1100 135.8   1e-30
XP_006722146 (OMIM: 607570) PREDICTED: probable AT ( 752)  998 124.6 2.5e-27
XP_016880572 (OMIM: 607570) PREDICTED: probable AT ( 640)  847 107.9 2.1e-22
XP_016880571 (OMIM: 607570) PREDICTED: probable AT ( 640)  847 107.9 2.1e-22
XP_011523556 (OMIM: 607570) PREDICTED: probable AT ( 680)  847 108.0 2.2e-22
NP_001159773 (OMIM: 607570) probable ATP-dependent ( 702)  847 108.0 2.3e-22
XP_016880569 (OMIM: 607570) PREDICTED: probable AT ( 723)  847 108.0 2.3e-22
NP_078888 (OMIM: 607570) probable ATP-dependent RN ( 779)  847 108.0 2.4e-22
XP_016880366 (OMIM: 614405) PREDICTED: putative AT ( 279)  694 90.7 1.4e-17
XP_011523555 (OMIM: 607570) PREDICTED: probable AT ( 718)  693 91.1 2.8e-17
NP_065916 (OMIM: 612767) ATP-dependent RNA helicas (1008)  615 82.7 1.3e-14
NP_001348 (OMIM: 603115) ATP-dependent RNA helicas (1270)  568 77.7 5.4e-13
XP_016880570 (OMIM: 607570) PREDICTED: probable AT ( 653)  560 76.5 6.5e-13
NP_001107869 (OMIM: 612767) ATP-dependent RNA heli ( 994)  536 74.1 5.3e-12
XP_016865224 (OMIM: 616530) PREDICTED: probable AT ( 971)  507 70.9 4.7e-11
NP_001332905 (OMIM: 616530) probable ATP-dependent (1130)  507 70.9 5.2e-11
XP_016865222 (OMIM: 616530) PREDICTED: probable AT (1139)  507 70.9 5.2e-11
XP_011541888 (OMIM: 616530) PREDICTED: probable AT (1162)  507 71.0 5.3e-11
NP_001332904 (OMIM: 616530) probable ATP-dependent (1268)  507 71.0 5.6e-11
XP_016865220 (OMIM: 616530) PREDICTED: probable AT (1277)  507 71.0 5.6e-11
XP_011541884 (OMIM: 616530) PREDICTED: probable AT (1406)  507 71.1   6e-11
NP_073739 (OMIM: 616530) probable ATP-dependent RN (1430)  507 71.1 6.1e-11


>>XP_011521786 (OMIM: 605584) PREDICTED: pre-mRNA-splici  (1227 aa)
 initn: 8205 init1: 8205 opt: 8205  Z-score: 4880.8  bits: 915.2 E(85289):    0
Smith-Waterman score: 8205; 99.9% identity (100.0% similar) in 1227 aa overlap (1-1227:1-1227)

               10        20        30        40        50        60
pF1KSD MGDTSEDASIHRLEGTDLDCQVGGLICKSKSAASEQHVFKAPAPRPSLLGLDLLASLKRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGDTSEDASIHRLEGTDLDCQVGGLICKSKSAASEQHVFKAPAPRPSLLGLDLLASLKRR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD EREEKDDGEDKKKSKVSSYKDWEESKDDQKDAEEEGGDQAGQNIRKDRHYRSARVETPSH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EREEKDDGEDKKKSKVSSYKDWEESKDDQKDAEEEGGDQAGQNIRKDRHYRSARVETPSH
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD PGGVSEEFWERSRQRERERREHGVYASSKEEKDWKKEKSRDRDYDRKRDRDERDRSRHSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGGVSEEFWERSRQRERERREHGVYASSKEEKDWKKEKSRDRDYDRKRDRDERDRSRHSS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD RSERDGGSERSSRRNEPESPRHRPKDAATPSRSTWEEEDSGYGSSRRSQWESPSPTPSYR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSERDGGSERSSRRNEPESPRHRPKDAATPSRSTWEEEDSGYGSSRRSQWESPSPTPSYR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD DSERSHRLSTRDRDRSVRGKYSDDTPLPTPSYKYNEWADDRRHLGSTPRLSRGRGRREEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSERSHRLSTRDRDRSVRGKYSDDTPLPTPSYKYNEWADDRRHLGSTPRLSRGRGRREEG
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD EEGISFDTEEERQQWEDDQRQADRDWYMMDEGYDEFHNPLAYSSEDYVRRREQHLHKQKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEGISFDTEEERQQWEDDQRQADRDWYMMDEGYDEFHNPLAYSSEDYVRRREQHLHKQKQ
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD KRISAQRRQINEDNERWETNRMLTSGVVHRLEVDEDFEEDNAAKVHLMVHNLVPPFLDGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRISAQRRQINEDNERWETNRMLTSGVVHRLEVDEDFEEDNAAKVHLMVHNLVPPFLDGR
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD IVFTKQPEPVIPVKDATSDLAIIARKGSQTVRKHREQKERKKAQHKHWELAGTKLGDIMG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IVFTKQPEPVIPVKDATSDLAIIARKGSQTVRKHREQKERKKAQHKHWELAGTKLGDIMG
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD VKKEEEPDKAVTEDGKVDYRTEQKFADHMKRKSEASSEFAKKKSILEQRQYLPIFAVQQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKKEEEPDKAVTEDGKVDYRTEQKFADHMKRKSEASSEFAKKKSILEQRQYLPIFAVQQE
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD LLTIIRDNSIVIVVGETGSGKTTQLTQYLHEDGYTDYGMIGCTQPRRVAAMSVAKRVSEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLTIIRDNSIVIVVGETGSGKTTQLTQYLHEDGYTDYGMIGCTQPRRVAAMSVAKRVSEE
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD MGGNLGEEVGYAIRFEDCTSENTLIKYMTDGILLRESLREADLDHYSAIIMDEAHERSLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGGNLGEEVGYAIRFEDCTSENTLIKYMTDGILLRESLREADLDHYSAIIMDEAHERSLN
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD TDVLFGLLREVVARRSDLKLIVTSATMDAEKFAAFFGNVPIFHIPGRTFPVDILFSKTPQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TDVLFGLLREVVARRSDLKLIVTSATMDAEKFAAFFGNVPIFHIPGRTFPVDILFSKTPQ
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD EDYVEAAVKQSLQVHLSGAPGDILIFMPGQEDIEVTSDQIVEHLEELENAPALAVLPIYS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDYVEAAVKQSLQVHLSGAPGDILIFMPGQEDIEVTSDQIVEHLEELENAPALAVLPIYS
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KSD QLPSDLQAKIFQKAPDGVRKCIVATNIAETSLTVDGIMFVIDSGYCKLKVFNPRIGMDAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLPSDLQAKIFQKAPDGVRKCIVATNIAETSLTVDGIMFVIDSGYCKLKVFNPRIGMDAL
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KSD QIYPISQANANQRSGRAGRTGPGQCFRLYTQSAYKNELLTTTVPEIQRTNLANVVLLLKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QIYPISQANANQRSGRAGRTGPGQCFRLYTQSAYKNELLTTTVPEIQRTNLANVVLLLKS
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KSD LGVQDLLQFHFMDPPPEDNMLNSMYQLWILGALDNTGGLTSTGRLMVEFPLDPALSKMLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGVQDLLQFHFMDPPPEDNMLNSMYQLWILGALDNTGGLTSTGRLMVEFPLDPALSKMLI
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KSD VSCDMGCSSEILLIVSMLSVPAIFYRPKGREEESDQIREKFAVPESDHLTYLNVYLQWKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSCDMGCSSEILLIVSMLSVPAIFYRPKGREEESDQIREKFAVPESDHLTYLNVYLQWKN
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KSD NNYSTIWCNDHFIHAKAMRKVREVRAQLKDIMVQQRMSLASCGTDWDIVRKCICAAYFHQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NNYSTIWCNDHFIHAKAMRKVREVRAQLKDIMVQQRMSLASCGTDWDIVRKCICAAYFHQ
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KSD AAKLKGIGEYVNIRTGMPCHLHPTSSLFGMGYTPDYIVYHELVMTTKEYMQCVTAVDGEW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAKLKGIGEYVNIRTGMPCHLHPTSSLFGMGYTPDYIVYHELVMTTKEYMQCVTAVDGEW
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KSD LAELGPMFYSVKQAGKSRQENRRRAKEEASAMEEEMALAEEQLRARRQEQEKRSPLGSVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAELGPMFYSVKQAGKSRQENRRRAKEEASAMEEEMALAEEQLRARRQEQEKRSPLGSVR
             1150      1160      1170      1180      1190      1200

             1210      1220       
pF1KSD STKIYTPGRKEQGEPMAPRRTPARFGL
       ::::::::::::::::.::::::::::
XP_011 STKIYTPGRKEQGEPMTPRRTPARFGL
             1210      1220       

>>NP_054722 (OMIM: 605584) pre-mRNA-splicing factor ATP-  (1227 aa)
 initn: 8205 init1: 8205 opt: 8205  Z-score: 4880.8  bits: 915.2 E(85289):    0
Smith-Waterman score: 8205; 99.9% identity (100.0% similar) in 1227 aa overlap (1-1227:1-1227)

               10        20        30        40        50        60
pF1KSD MGDTSEDASIHRLEGTDLDCQVGGLICKSKSAASEQHVFKAPAPRPSLLGLDLLASLKRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 MGDTSEDASIHRLEGTDLDCQVGGLICKSKSAASEQHVFKAPAPRPSLLGLDLLASLKRR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD EREEKDDGEDKKKSKVSSYKDWEESKDDQKDAEEEGGDQAGQNIRKDRHYRSARVETPSH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 EREEKDDGEDKKKSKVSSYKDWEESKDDQKDAEEEGGDQAGQNIRKDRHYRSARVETPSH
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD PGGVSEEFWERSRQRERERREHGVYASSKEEKDWKKEKSRDRDYDRKRDRDERDRSRHSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 PGGVSEEFWERSRQRERERREHGVYASSKEEKDWKKEKSRDRDYDRKRDRDERDRSRHSS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD RSERDGGSERSSRRNEPESPRHRPKDAATPSRSTWEEEDSGYGSSRRSQWESPSPTPSYR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 RSERDGGSERSSRRNEPESPRHRPKDAATPSRSTWEEEDSGYGSSRRSQWESPSPTPSYR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD DSERSHRLSTRDRDRSVRGKYSDDTPLPTPSYKYNEWADDRRHLGSTPRLSRGRGRREEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 DSERSHRLSTRDRDRSVRGKYSDDTPLPTPSYKYNEWADDRRHLGSTPRLSRGRGRREEG
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD EEGISFDTEEERQQWEDDQRQADRDWYMMDEGYDEFHNPLAYSSEDYVRRREQHLHKQKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 EEGISFDTEEERQQWEDDQRQADRDWYMMDEGYDEFHNPLAYSSEDYVRRREQHLHKQKQ
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD KRISAQRRQINEDNERWETNRMLTSGVVHRLEVDEDFEEDNAAKVHLMVHNLVPPFLDGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 KRISAQRRQINEDNERWETNRMLTSGVVHRLEVDEDFEEDNAAKVHLMVHNLVPPFLDGR
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD IVFTKQPEPVIPVKDATSDLAIIARKGSQTVRKHREQKERKKAQHKHWELAGTKLGDIMG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 IVFTKQPEPVIPVKDATSDLAIIARKGSQTVRKHREQKERKKAQHKHWELAGTKLGDIMG
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD VKKEEEPDKAVTEDGKVDYRTEQKFADHMKRKSEASSEFAKKKSILEQRQYLPIFAVQQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 VKKEEEPDKAVTEDGKVDYRTEQKFADHMKRKSEASSEFAKKKSILEQRQYLPIFAVQQE
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD LLTIIRDNSIVIVVGETGSGKTTQLTQYLHEDGYTDYGMIGCTQPRRVAAMSVAKRVSEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 LLTIIRDNSIVIVVGETGSGKTTQLTQYLHEDGYTDYGMIGCTQPRRVAAMSVAKRVSEE
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD MGGNLGEEVGYAIRFEDCTSENTLIKYMTDGILLRESLREADLDHYSAIIMDEAHERSLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 MGGNLGEEVGYAIRFEDCTSENTLIKYMTDGILLRESLREADLDHYSAIIMDEAHERSLN
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD TDVLFGLLREVVARRSDLKLIVTSATMDAEKFAAFFGNVPIFHIPGRTFPVDILFSKTPQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 TDVLFGLLREVVARRSDLKLIVTSATMDAEKFAAFFGNVPIFHIPGRTFPVDILFSKTPQ
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD EDYVEAAVKQSLQVHLSGAPGDILIFMPGQEDIEVTSDQIVEHLEELENAPALAVLPIYS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 EDYVEAAVKQSLQVHLSGAPGDILIFMPGQEDIEVTSDQIVEHLEELENAPALAVLPIYS
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KSD QLPSDLQAKIFQKAPDGVRKCIVATNIAETSLTVDGIMFVIDSGYCKLKVFNPRIGMDAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 QLPSDLQAKIFQKAPDGVRKCIVATNIAETSLTVDGIMFVIDSGYCKLKVFNPRIGMDAL
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KSD QIYPISQANANQRSGRAGRTGPGQCFRLYTQSAYKNELLTTTVPEIQRTNLANVVLLLKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 QIYPISQANANQRSGRAGRTGPGQCFRLYTQSAYKNELLTTTVPEIQRTNLANVVLLLKS
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KSD LGVQDLLQFHFMDPPPEDNMLNSMYQLWILGALDNTGGLTSTGRLMVEFPLDPALSKMLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 LGVQDLLQFHFMDPPPEDNMLNSMYQLWILGALDNTGGLTSTGRLMVEFPLDPALSKMLI
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KSD VSCDMGCSSEILLIVSMLSVPAIFYRPKGREEESDQIREKFAVPESDHLTYLNVYLQWKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 VSCDMGCSSEILLIVSMLSVPAIFYRPKGREEESDQIREKFAVPESDHLTYLNVYLQWKN
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KSD NNYSTIWCNDHFIHAKAMRKVREVRAQLKDIMVQQRMSLASCGTDWDIVRKCICAAYFHQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 NNYSTIWCNDHFIHAKAMRKVREVRAQLKDIMVQQRMSLASCGTDWDIVRKCICAAYFHQ
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KSD AAKLKGIGEYVNIRTGMPCHLHPTSSLFGMGYTPDYIVYHELVMTTKEYMQCVTAVDGEW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 AAKLKGIGEYVNIRTGMPCHLHPTSSLFGMGYTPDYIVYHELVMTTKEYMQCVTAVDGEW
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KSD LAELGPMFYSVKQAGKSRQENRRRAKEEASAMEEEMALAEEQLRARRQEQEKRSPLGSVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 LAELGPMFYSVKQAGKSRQENRRRAKEEASAMEEEMALAEEQLRARRQEQEKRSPLGSVR
             1150      1160      1170      1180      1190      1200

             1210      1220       
pF1KSD STKIYTPGRKEQGEPMAPRRTPARFGL
       ::::::::::::::::.::::::::::
NP_054 STKIYTPGRKEQGEPMTPRRTPARFGL
             1210      1220       

>>XP_011521787 (OMIM: 605584) PREDICTED: pre-mRNA-splici  (1227 aa)
 initn: 8205 init1: 8205 opt: 8205  Z-score: 4880.8  bits: 915.2 E(85289):    0
Smith-Waterman score: 8205; 99.9% identity (100.0% similar) in 1227 aa overlap (1-1227:1-1227)

               10        20        30        40        50        60
pF1KSD MGDTSEDASIHRLEGTDLDCQVGGLICKSKSAASEQHVFKAPAPRPSLLGLDLLASLKRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGDTSEDASIHRLEGTDLDCQVGGLICKSKSAASEQHVFKAPAPRPSLLGLDLLASLKRR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD EREEKDDGEDKKKSKVSSYKDWEESKDDQKDAEEEGGDQAGQNIRKDRHYRSARVETPSH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EREEKDDGEDKKKSKVSSYKDWEESKDDQKDAEEEGGDQAGQNIRKDRHYRSARVETPSH
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD PGGVSEEFWERSRQRERERREHGVYASSKEEKDWKKEKSRDRDYDRKRDRDERDRSRHSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGGVSEEFWERSRQRERERREHGVYASSKEEKDWKKEKSRDRDYDRKRDRDERDRSRHSS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD RSERDGGSERSSRRNEPESPRHRPKDAATPSRSTWEEEDSGYGSSRRSQWESPSPTPSYR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSERDGGSERSSRRNEPESPRHRPKDAATPSRSTWEEEDSGYGSSRRSQWESPSPTPSYR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD DSERSHRLSTRDRDRSVRGKYSDDTPLPTPSYKYNEWADDRRHLGSTPRLSRGRGRREEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSERSHRLSTRDRDRSVRGKYSDDTPLPTPSYKYNEWADDRRHLGSTPRLSRGRGRREEG
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD EEGISFDTEEERQQWEDDQRQADRDWYMMDEGYDEFHNPLAYSSEDYVRRREQHLHKQKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEGISFDTEEERQQWEDDQRQADRDWYMMDEGYDEFHNPLAYSSEDYVRRREQHLHKQKQ
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD KRISAQRRQINEDNERWETNRMLTSGVVHRLEVDEDFEEDNAAKVHLMVHNLVPPFLDGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRISAQRRQINEDNERWETNRMLTSGVVHRLEVDEDFEEDNAAKVHLMVHNLVPPFLDGR
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD IVFTKQPEPVIPVKDATSDLAIIARKGSQTVRKHREQKERKKAQHKHWELAGTKLGDIMG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IVFTKQPEPVIPVKDATSDLAIIARKGSQTVRKHREQKERKKAQHKHWELAGTKLGDIMG
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD VKKEEEPDKAVTEDGKVDYRTEQKFADHMKRKSEASSEFAKKKSILEQRQYLPIFAVQQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKKEEEPDKAVTEDGKVDYRTEQKFADHMKRKSEASSEFAKKKSILEQRQYLPIFAVQQE
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD LLTIIRDNSIVIVVGETGSGKTTQLTQYLHEDGYTDYGMIGCTQPRRVAAMSVAKRVSEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLTIIRDNSIVIVVGETGSGKTTQLTQYLHEDGYTDYGMIGCTQPRRVAAMSVAKRVSEE
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD MGGNLGEEVGYAIRFEDCTSENTLIKYMTDGILLRESLREADLDHYSAIIMDEAHERSLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGGNLGEEVGYAIRFEDCTSENTLIKYMTDGILLRESLREADLDHYSAIIMDEAHERSLN
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD TDVLFGLLREVVARRSDLKLIVTSATMDAEKFAAFFGNVPIFHIPGRTFPVDILFSKTPQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TDVLFGLLREVVARRSDLKLIVTSATMDAEKFAAFFGNVPIFHIPGRTFPVDILFSKTPQ
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD EDYVEAAVKQSLQVHLSGAPGDILIFMPGQEDIEVTSDQIVEHLEELENAPALAVLPIYS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDYVEAAVKQSLQVHLSGAPGDILIFMPGQEDIEVTSDQIVEHLEELENAPALAVLPIYS
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KSD QLPSDLQAKIFQKAPDGVRKCIVATNIAETSLTVDGIMFVIDSGYCKLKVFNPRIGMDAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLPSDLQAKIFQKAPDGVRKCIVATNIAETSLTVDGIMFVIDSGYCKLKVFNPRIGMDAL
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KSD QIYPISQANANQRSGRAGRTGPGQCFRLYTQSAYKNELLTTTVPEIQRTNLANVVLLLKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QIYPISQANANQRSGRAGRTGPGQCFRLYTQSAYKNELLTTTVPEIQRTNLANVVLLLKS
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KSD LGVQDLLQFHFMDPPPEDNMLNSMYQLWILGALDNTGGLTSTGRLMVEFPLDPALSKMLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGVQDLLQFHFMDPPPEDNMLNSMYQLWILGALDNTGGLTSTGRLMVEFPLDPALSKMLI
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KSD VSCDMGCSSEILLIVSMLSVPAIFYRPKGREEESDQIREKFAVPESDHLTYLNVYLQWKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSCDMGCSSEILLIVSMLSVPAIFYRPKGREEESDQIREKFAVPESDHLTYLNVYLQWKN
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KSD NNYSTIWCNDHFIHAKAMRKVREVRAQLKDIMVQQRMSLASCGTDWDIVRKCICAAYFHQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NNYSTIWCNDHFIHAKAMRKVREVRAQLKDIMVQQRMSLASCGTDWDIVRKCICAAYFHQ
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KSD AAKLKGIGEYVNIRTGMPCHLHPTSSLFGMGYTPDYIVYHELVMTTKEYMQCVTAVDGEW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAKLKGIGEYVNIRTGMPCHLHPTSSLFGMGYTPDYIVYHELVMTTKEYMQCVTAVDGEW
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KSD LAELGPMFYSVKQAGKSRQENRRRAKEEASAMEEEMALAEEQLRARRQEQEKRSPLGSVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAELGPMFYSVKQAGKSRQENRRRAKEEASAMEEEMALAEEQLRARRQEQEKRSPLGSVR
             1150      1160      1170      1180      1190      1200

             1210      1220       
pF1KSD STKIYTPGRKEQGEPMAPRRTPARFGL
       ::::::::::::::::.::::::::::
XP_011 STKIYTPGRKEQGEPMTPRRTPARFGL
             1210      1220       

>>XP_005256326 (OMIM: 605584) PREDICTED: pre-mRNA-splici  (1192 aa)
 initn: 6825 init1: 6825 opt: 6892  Z-score: 4102.7  bits: 771.2 E(85289):    0
Smith-Waterman score: 7882; 97.1% identity (97.1% similar) in 1227 aa overlap (1-1227:1-1192)

               10        20        30        40        50        60
pF1KSD MGDTSEDASIHRLEGTDLDCQVGGLICKSKSAASEQHVFKAPAPRPSLLGLDLLASLKRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MGDTSEDASIHRLEGTDLDCQVGGLICKSKSAASEQHVFKAPAPRPSLLGLDLLASLKRR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD EREEKDDGEDKKKSKVSSYKDWEESKDDQKDAEEEGGDQAGQNIRKDRHYRSARVETPSH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EREEKDDGEDKKKSKVSSYKDWEESKDDQKDAEEEGGDQAGQNIRKDRHYRSARVETPSH
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD PGGVSEEFWERSRQRERERREHGVYASSKEEKDWKKEKSRDRDYDRKRDRDERDRSRHSS
       :::::::::::::::::::::::::::::::::::::::::::::::::::         
XP_005 PGGVSEEFWERSRQRERERREHGVYASSKEEKDWKKEKSRDRDYDRKRDRD---------
              130       140       150       160       170          

              190       200       210       220       230       240
pF1KSD RSERDGGSERSSRRNEPESPRHRPKDAATPSRSTWEEEDSGYGSSRRSQWESPSPTPSYR
                                 ::::::::::::::::::::::::::::::::::
XP_005 --------------------------AATPSRSTWEEEDSGYGSSRRSQWESPSPTPSYR
                                       180       190       200     

              250       260       270       280       290       300
pF1KSD DSERSHRLSTRDRDRSVRGKYSDDTPLPTPSYKYNEWADDRRHLGSTPRLSRGRGRREEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DSERSHRLSTRDRDRSVRGKYSDDTPLPTPSYKYNEWADDRRHLGSTPRLSRGRGRREEG
         210       220       230       240       250       260     

              310       320       330       340       350       360
pF1KSD EEGISFDTEEERQQWEDDQRQADRDWYMMDEGYDEFHNPLAYSSEDYVRRREQHLHKQKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EEGISFDTEEERQQWEDDQRQADRDWYMMDEGYDEFHNPLAYSSEDYVRRREQHLHKQKQ
         270       280       290       300       310       320     

              370       380       390       400       410       420
pF1KSD KRISAQRRQINEDNERWETNRMLTSGVVHRLEVDEDFEEDNAAKVHLMVHNLVPPFLDGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KRISAQRRQINEDNERWETNRMLTSGVVHRLEVDEDFEEDNAAKVHLMVHNLVPPFLDGR
         330       340       350       360       370       380     

              430       440       450       460       470       480
pF1KSD IVFTKQPEPVIPVKDATSDLAIIARKGSQTVRKHREQKERKKAQHKHWELAGTKLGDIMG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IVFTKQPEPVIPVKDATSDLAIIARKGSQTVRKHREQKERKKAQHKHWELAGTKLGDIMG
         390       400       410       420       430       440     

              490       500       510       520       530       540
pF1KSD VKKEEEPDKAVTEDGKVDYRTEQKFADHMKRKSEASSEFAKKKSILEQRQYLPIFAVQQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VKKEEEPDKAVTEDGKVDYRTEQKFADHMKRKSEASSEFAKKKSILEQRQYLPIFAVQQE
         450       460       470       480       490       500     

              550       560       570       580       590       600
pF1KSD LLTIIRDNSIVIVVGETGSGKTTQLTQYLHEDGYTDYGMIGCTQPRRVAAMSVAKRVSEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLTIIRDNSIVIVVGETGSGKTTQLTQYLHEDGYTDYGMIGCTQPRRVAAMSVAKRVSEE
         510       520       530       540       550       560     

              610       620       630       640       650       660
pF1KSD MGGNLGEEVGYAIRFEDCTSENTLIKYMTDGILLRESLREADLDHYSAIIMDEAHERSLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MGGNLGEEVGYAIRFEDCTSENTLIKYMTDGILLRESLREADLDHYSAIIMDEAHERSLN
         570       580       590       600       610       620     

              670       680       690       700       710       720
pF1KSD TDVLFGLLREVVARRSDLKLIVTSATMDAEKFAAFFGNVPIFHIPGRTFPVDILFSKTPQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TDVLFGLLREVVARRSDLKLIVTSATMDAEKFAAFFGNVPIFHIPGRTFPVDILFSKTPQ
         630       640       650       660       670       680     

              730       740       750       760       770       780
pF1KSD EDYVEAAVKQSLQVHLSGAPGDILIFMPGQEDIEVTSDQIVEHLEELENAPALAVLPIYS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EDYVEAAVKQSLQVHLSGAPGDILIFMPGQEDIEVTSDQIVEHLEELENAPALAVLPIYS
         690       700       710       720       730       740     

              790       800       810       820       830       840
pF1KSD QLPSDLQAKIFQKAPDGVRKCIVATNIAETSLTVDGIMFVIDSGYCKLKVFNPRIGMDAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QLPSDLQAKIFQKAPDGVRKCIVATNIAETSLTVDGIMFVIDSGYCKLKVFNPRIGMDAL
         750       760       770       780       790       800     

              850       860       870       880       890       900
pF1KSD QIYPISQANANQRSGRAGRTGPGQCFRLYTQSAYKNELLTTTVPEIQRTNLANVVLLLKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QIYPISQANANQRSGRAGRTGPGQCFRLYTQSAYKNELLTTTVPEIQRTNLANVVLLLKS
         810       820       830       840       850       860     

              910       920       930       940       950       960
pF1KSD LGVQDLLQFHFMDPPPEDNMLNSMYQLWILGALDNTGGLTSTGRLMVEFPLDPALSKMLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LGVQDLLQFHFMDPPPEDNMLNSMYQLWILGALDNTGGLTSTGRLMVEFPLDPALSKMLI
         870       880       890       900       910       920     

              970       980       990      1000      1010      1020
pF1KSD VSCDMGCSSEILLIVSMLSVPAIFYRPKGREEESDQIREKFAVPESDHLTYLNVYLQWKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VSCDMGCSSEILLIVSMLSVPAIFYRPKGREEESDQIREKFAVPESDHLTYLNVYLQWKN
         930       940       950       960       970       980     

             1030      1040      1050      1060      1070      1080
pF1KSD NNYSTIWCNDHFIHAKAMRKVREVRAQLKDIMVQQRMSLASCGTDWDIVRKCICAAYFHQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NNYSTIWCNDHFIHAKAMRKVREVRAQLKDIMVQQRMSLASCGTDWDIVRKCICAAYFHQ
         990      1000      1010      1020      1030      1040     

             1090      1100      1110      1120      1130      1140
pF1KSD AAKLKGIGEYVNIRTGMPCHLHPTSSLFGMGYTPDYIVYHELVMTTKEYMQCVTAVDGEW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AAKLKGIGEYVNIRTGMPCHLHPTSSLFGMGYTPDYIVYHELVMTTKEYMQCVTAVDGEW
        1050      1060      1070      1080      1090      1100     

             1150      1160      1170      1180      1190      1200
pF1KSD LAELGPMFYSVKQAGKSRQENRRRAKEEASAMEEEMALAEEQLRARRQEQEKRSPLGSVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LAELGPMFYSVKQAGKSRQENRRRAKEEASAMEEEMALAEEQLRARRQEQEKRSPLGSVR
        1110      1120      1130      1140      1150      1160     

             1210      1220       
pF1KSD STKIYTPGRKEQGEPMAPRRTPARFGL
       ::::::::::::::::.::::::::::
XP_005 STKIYTPGRKEQGEPMTPRRTPARFGL
        1170      1180      1190  

>>XP_016879402 (OMIM: 605584) PREDICTED: pre-mRNA-splici  (1192 aa)
 initn: 6825 init1: 6825 opt: 6892  Z-score: 4102.7  bits: 771.2 E(85289):    0
Smith-Waterman score: 7882; 97.1% identity (97.1% similar) in 1227 aa overlap (1-1227:1-1192)

               10        20        30        40        50        60
pF1KSD MGDTSEDASIHRLEGTDLDCQVGGLICKSKSAASEQHVFKAPAPRPSLLGLDLLASLKRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGDTSEDASIHRLEGTDLDCQVGGLICKSKSAASEQHVFKAPAPRPSLLGLDLLASLKRR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD EREEKDDGEDKKKSKVSSYKDWEESKDDQKDAEEEGGDQAGQNIRKDRHYRSARVETPSH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EREEKDDGEDKKKSKVSSYKDWEESKDDQKDAEEEGGDQAGQNIRKDRHYRSARVETPSH
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD PGGVSEEFWERSRQRERERREHGVYASSKEEKDWKKEKSRDRDYDRKRDRDERDRSRHSS
       :::::::::::::::::::::::::::::::::::::::::::::::::::         
XP_016 PGGVSEEFWERSRQRERERREHGVYASSKEEKDWKKEKSRDRDYDRKRDRD---------
              130       140       150       160       170          

              190       200       210       220       230       240
pF1KSD RSERDGGSERSSRRNEPESPRHRPKDAATPSRSTWEEEDSGYGSSRRSQWESPSPTPSYR
                                 ::::::::::::::::::::::::::::::::::
XP_016 --------------------------AATPSRSTWEEEDSGYGSSRRSQWESPSPTPSYR
                                       180       190       200     

              250       260       270       280       290       300
pF1KSD DSERSHRLSTRDRDRSVRGKYSDDTPLPTPSYKYNEWADDRRHLGSTPRLSRGRGRREEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSERSHRLSTRDRDRSVRGKYSDDTPLPTPSYKYNEWADDRRHLGSTPRLSRGRGRREEG
         210       220       230       240       250       260     

              310       320       330       340       350       360
pF1KSD EEGISFDTEEERQQWEDDQRQADRDWYMMDEGYDEFHNPLAYSSEDYVRRREQHLHKQKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEGISFDTEEERQQWEDDQRQADRDWYMMDEGYDEFHNPLAYSSEDYVRRREQHLHKQKQ
         270       280       290       300       310       320     

              370       380       390       400       410       420
pF1KSD KRISAQRRQINEDNERWETNRMLTSGVVHRLEVDEDFEEDNAAKVHLMVHNLVPPFLDGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRISAQRRQINEDNERWETNRMLTSGVVHRLEVDEDFEEDNAAKVHLMVHNLVPPFLDGR
         330       340       350       360       370       380     

              430       440       450       460       470       480
pF1KSD IVFTKQPEPVIPVKDATSDLAIIARKGSQTVRKHREQKERKKAQHKHWELAGTKLGDIMG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IVFTKQPEPVIPVKDATSDLAIIARKGSQTVRKHREQKERKKAQHKHWELAGTKLGDIMG
         390       400       410       420       430       440     

              490       500       510       520       530       540
pF1KSD VKKEEEPDKAVTEDGKVDYRTEQKFADHMKRKSEASSEFAKKKSILEQRQYLPIFAVQQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKKEEEPDKAVTEDGKVDYRTEQKFADHMKRKSEASSEFAKKKSILEQRQYLPIFAVQQE
         450       460       470       480       490       500     

              550       560       570       580       590       600
pF1KSD LLTIIRDNSIVIVVGETGSGKTTQLTQYLHEDGYTDYGMIGCTQPRRVAAMSVAKRVSEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLTIIRDNSIVIVVGETGSGKTTQLTQYLHEDGYTDYGMIGCTQPRRVAAMSVAKRVSEE
         510       520       530       540       550       560     

              610       620       630       640       650       660
pF1KSD MGGNLGEEVGYAIRFEDCTSENTLIKYMTDGILLRESLREADLDHYSAIIMDEAHERSLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGGNLGEEVGYAIRFEDCTSENTLIKYMTDGILLRESLREADLDHYSAIIMDEAHERSLN
         570       580       590       600       610       620     

              670       680       690       700       710       720
pF1KSD TDVLFGLLREVVARRSDLKLIVTSATMDAEKFAAFFGNVPIFHIPGRTFPVDILFSKTPQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TDVLFGLLREVVARRSDLKLIVTSATMDAEKFAAFFGNVPIFHIPGRTFPVDILFSKTPQ
         630       640       650       660       670       680     

              730       740       750       760       770       780
pF1KSD EDYVEAAVKQSLQVHLSGAPGDILIFMPGQEDIEVTSDQIVEHLEELENAPALAVLPIYS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDYVEAAVKQSLQVHLSGAPGDILIFMPGQEDIEVTSDQIVEHLEELENAPALAVLPIYS
         690       700       710       720       730       740     

              790       800       810       820       830       840
pF1KSD QLPSDLQAKIFQKAPDGVRKCIVATNIAETSLTVDGIMFVIDSGYCKLKVFNPRIGMDAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLPSDLQAKIFQKAPDGVRKCIVATNIAETSLTVDGIMFVIDSGYCKLKVFNPRIGMDAL
         750       760       770       780       790       800     

              850       860       870       880       890       900
pF1KSD QIYPISQANANQRSGRAGRTGPGQCFRLYTQSAYKNELLTTTVPEIQRTNLANVVLLLKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QIYPISQANANQRSGRAGRTGPGQCFRLYTQSAYKNELLTTTVPEIQRTNLANVVLLLKS
         810       820       830       840       850       860     

              910       920       930       940       950       960
pF1KSD LGVQDLLQFHFMDPPPEDNMLNSMYQLWILGALDNTGGLTSTGRLMVEFPLDPALSKMLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGVQDLLQFHFMDPPPEDNMLNSMYQLWILGALDNTGGLTSTGRLMVEFPLDPALSKMLI
         870       880       890       900       910       920     

              970       980       990      1000      1010      1020
pF1KSD VSCDMGCSSEILLIVSMLSVPAIFYRPKGREEESDQIREKFAVPESDHLTYLNVYLQWKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSCDMGCSSEILLIVSMLSVPAIFYRPKGREEESDQIREKFAVPESDHLTYLNVYLQWKN
         930       940       950       960       970       980     

             1030      1040      1050      1060      1070      1080
pF1KSD NNYSTIWCNDHFIHAKAMRKVREVRAQLKDIMVQQRMSLASCGTDWDIVRKCICAAYFHQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NNYSTIWCNDHFIHAKAMRKVREVRAQLKDIMVQQRMSLASCGTDWDIVRKCICAAYFHQ
         990      1000      1010      1020      1030      1040     

             1090      1100      1110      1120      1130      1140
pF1KSD AAKLKGIGEYVNIRTGMPCHLHPTSSLFGMGYTPDYIVYHELVMTTKEYMQCVTAVDGEW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAKLKGIGEYVNIRTGMPCHLHPTSSLFGMGYTPDYIVYHELVMTTKEYMQCVTAVDGEW
        1050      1060      1070      1080      1090      1100     

             1150      1160      1170      1180      1190      1200
pF1KSD LAELGPMFYSVKQAGKSRQENRRRAKEEASAMEEEMALAEEQLRARRQEQEKRSPLGSVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAELGPMFYSVKQAGKSRQENRRRAKEEASAMEEEMALAEEQLRARRQEQEKRSPLGSVR
        1110      1120      1130      1140      1150      1160     

             1210      1220       
pF1KSD STKIYTPGRKEQGEPMAPRRTPARFGL
       ::::::::::::::::.::::::::::
XP_016 STKIYTPGRKEQGEPMTPRRTPARFGL
        1170      1180      1190  

>>NP_001309146 (OMIM: 600396) ATP-dependent RNA helicase  (1129 aa)
 initn: 2544 init1: 1248 opt: 2545  Z-score: 1526.6  bits: 294.4 E(85289): 2.7e-78
Smith-Waterman score: 2617; 41.4% identity (69.5% similar) in 1084 aa overlap (133-1177:70-1119)

            110       120       130       140       150       160  
pF1KSD NIRKDRHYRSARVETPSHPGGVSEEFWERSRQRERERREHGVYASSKEEKDWKKEKSRDR
                                     .::. :.:..    ..:.... .....:::
NP_001 RTMLDEDDVKVAVDVLKELEALMPSAAGQEKQRDAEHRDR----TKKKKRSRSRDRNRDR
      40        50        60        70            80        90     

            170       180       190       200       210       220  
pF1KSD DYDRKRDRDERDRSRHSSRSERDGGSERSSRRNEPESPRHRPKDAATPSRSTWEEEDSGY
       : ::.:.::.  . :: :::.   .  :. .::. .: :.: .. .    .  ...:. :
NP_001 DRDRERNRDRDHKRRHRSRSR---SRSRTRERNKVKS-RYRSRSRSQSPPKDRKDRDK-Y
         100       110          120        130       140        150

            230             240       250       260       270      
pF1KSD GSSRRSQW-----ESPSPT-PSYRDSERSHRLSTRDRDRSVRGKYSDDTPLPTPSYKYNE
       :    ..:     . : :  :.  :   ..  :  .      : . .   :        .
NP_001 GERNLDRWRDKHVDRPPPEEPTIGDIYNGKVTSIMQF-----GCFVQLEGLRKRWEGLVH
              160       170       180            190       200     

        280       290         300       310        320       330   
pF1KSD WADDRRHLGSTPRLSR--GRGRREEGEEGISFDTEEERQQWED-DQRQADRDWYMMDEGY
        .. ::. : .  ..   ..:.: . .  .::   .   . .: ::. ..      : . 
NP_001 ISELRRE-GRVANVADVVSKGQRVKVKV-LSFTGTKTSLSMKDVDQETGE------DLNP
         210        220       230        240       250             

           340       350          360          370         380     
pF1KSD DEFHNPLAYSSEDYVRR---REQHLHKQKQKRI---SAQRRQINE--DNERWETNRMLTS
       .. .: .. ..:.   :   :  ::   .  ..   : .:.....  : :.:: ..:...
NP_001 NRRRNLVGETNEETSMRNPDRPTHLSLVSAPEVEDDSLERKRLTRISDPEKWEIKQMIAA
       260       270       280       290       300       310       

         390                  400       410       420       430    
pF1KSD GVVHRLEV---DE--------DFEEDNAAKVHLMVHNLVPPFLDGRIVFTKQPEPVIPVK
       .:. . :    ::        : :::.  ...:. ..  :::: :.   . .  :.  ::
NP_001 NVLSKEEFPDFDEETGILPKVDDEEDEDLEIELVEEE--PPFLRGHTKQSMDMSPIKIVK
       320       330       340       350         360       370     

          440       450        460               470       480     
pF1KSD DATSDLAIIARKGSQTVRKHREQKE-RKKAQ--------HKHWELAGTKLGDIMGVKKEE
       .  ..:.  :   :  ....:: :. ...:.        .:::      : :  : .   
NP_001 NPDGSLSQAAMMQSALAKERRELKQAQREAEMDSIPMGLNKHWV---DPLPDAEGRQIAA
         380       390       400       410          420       430  

         490       500       510       520       530       540     
pF1KSD EPDKAVTEDGKVDYRTEQKFADHMKRKSEASSEFAKKKSILEQRQYLPIFAVQQELLTII
       .        . .    .. :. .     .::     . ::::::. :::. ....:.  .
NP_001 NMRGIGMMPNDIPEWKKHAFGGN-----KASYGKKTQMSILEQRESLPIYKLKEQLVQAV
            440       450            460       470       480       

         550       560       570       580       590       600     
pF1KSD RDNSIVIVVGETGSGKTTQLTQYLHEDGYTDYGMIGCTQPRRVAAMSVAKRVSEEMGGNL
       .::.:.::.::::::::::.:::: : :::. : :::::::::::::::::::::.:  :
NP_001 HDNQILIVIGETGSGKTTQITQYLAEAGYTSRGKIGCTQPRRVAAMSVAKRVSEEFGCCL
       490       500       510       520       530       540       

         610       620       630       640       650       660     
pF1KSD GEEVGYAIRFEDCTSENTLIKYMTDGILLRESLREADLDHYSAIIMDEAHERSLNTDVLF
       :.::::.:::::::: .:.:::::::.:::: : . :: .:. :..::::::...:::::
NP_001 GQEVGYTIRFEDCTSPETVIKYMTDGMLLRECLIDPDLTQYAIIMLDEAHERTIHTDVLF
       550       560       570       580       590       600       

         670       680       690       700       710       720     
pF1KSD GLLREVVARRSDLKLIVTSATMDAEKFAAFFGNVPIFHIPGRTFPVDILFSKTPQEDYVE
       :::...: .:.:.::::::::.:: ::. .: ..::: :::::.::.::..: :. ::..
NP_001 GLLKKTVQKRQDMKLIVTSATLDAVKFSQYFYEAPIFTIPGRTYPVEILYTKEPETDYLD
       610       620       630       640       650       660       

         730       740       750       760        770       780    
pF1KSD AAVKQSLQVHLSGAPGDILIFMPGQEDIEVTSDQIVEHLEEL-ENAPALAVLPIYSQLPS
       :..   .:.::.  :::::.:. :::.:... . . :... :  ..: : .::.:: :::
NP_001 ASLITVMQIHLTEPPGDILVFLTGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPS
       670       680       690       700       710       720       

          790       800       810       820       830       840    
pF1KSD DLQAKIFQKAPDGVRKCIVATNIAETSLTVDGIMFVIDSGYCKLKVFNPRIGMDALQIYP
       ..:..::. :: : :: ..::::::::::.:::..:.: :. : ::.: . :.: : . :
NP_001 EMQTRIFDPAPPGSRKVVIATNIAETSLTIDGIYYVVDPGFVKQKVYNSKTGIDQLVVTP
       730       740       750       760       770       780       

          850       860       870       880       890       900    
pF1KSD ISQANANQRSGRAGRTGPGQCFRLYTQSAYKNELLTTTVPEIQRTNLANVVLLLKSLGVQ
       ::::.:.::.:::::::::.:.::::. ::..:.:::.::::::::::..:: ::..:..
NP_001 ISQAQAKQRAGRAGRTGPGKCYRLYTERAYRDEMLTTNVPEIQRTNLASTVLSLKAMGIN
       790       800       810       820       830       840       

          910       920       930       940       950       960    
pF1KSD DLLQFHFMDPPPEDNMLNSMYQLWILGALDNTGGLTSTGRLMVEFPLDPALSKMLIVSCD
       :::.: ::: :: ......: ::. :::::. : ::  :: :.::::.: : ::::.:  
NP_001 DLLSFDFMDAPPMETLITAMEQLYTLGALDDEGLLTRLGRRMAEFPLEPMLCKMLIMSVH
       850       860       870       880       890       900       

          970       980       990      1000      1010      1020    
pF1KSD MGCSSEILLIVSMLSVPAIFYRPKGREEESDQIREKFAVPESDHLTYLNVYLQWKNNNYS
       .::: :.: :::::::  .::::: ..  .:: . ::   :.:::: : :: .::::..:
NP_001 LGCSEEMLTIVSMLSVQNVFYRPKDKQALADQKKAKFHQTEGDHLTLLAVYNSWKNNKFS
       910       920       930       940       950       960       

         1030      1040      1050      1060      1070      1080    
pF1KSD TIWCNDHFIHAKAMRKVREVRAQLKDIMVQQRMSLASCGTDWDIVRKCICAAYFHQAAKL
       . :: ..::.:...:.....: :.  :: .......::: .   :.: ::...:..::: 
NP_001 NPWCYENFIQARSLRRAQDIRKQMLGIMDRHKLDVVSCGKSTVRVQKAICSGFFRNAAKK
       970       980       990      1000      1010      1020       

         1090      1100      1110      1120      1130      1140    
pF1KSD KGIGEYVNIRTGMPCHLHPTSSLFGMGYTPDYIVYHELVMTTKEYMQCVTAVDGEWLAEL
            : ..   .  ..::.:.::.    :...::::::.::::::. ::..: .::.:.
NP_001 DPQEGYRTLIDQQVVYIHPSSALFN--RQPEWVVYHELVLTTKEYMREVTTIDPRWLVEF
      1030      1040      1050        1060      1070      1080     

         1150       1160      1170      1180      1190      1200   
pF1KSD GPMFYSVKQAGK-SRQENRRRAKEEASAMEEEMALAEEQLRARRQEQEKRSPLGSVRSTK
       .: :..:..  : :.:....: .   . .::  :                          
NP_001 APAFFKVSDPTKLSKQKKQQRLEPLYNRYEEPNAWRISRAFRRR                
        1090      1100      1110      1120                         

          1210      1220       
pF1KSD IYTPGRKEQGEPMAPRRTPARFGL

>>NP_004932 (OMIM: 600396) ATP-dependent RNA helicase DH  (1220 aa)
 initn: 2544 init1: 1248 opt: 2545  Z-score: 1526.2  bits: 294.5 E(85289): 2.9e-78
Smith-Waterman score: 2617; 41.4% identity (69.5% similar) in 1084 aa overlap (133-1177:161-1210)

            110       120       130       140       150       160  
pF1KSD NIRKDRHYRSARVETPSHPGGVSEEFWERSRQRERERREHGVYASSKEEKDWKKEKSRDR
                                     .::. :.:..    ..:.... .....:::
NP_004 RTMLDEDDVKVAVDVLKELEALMPSAAGQEKQRDAEHRDR----TKKKKRSRSRDRNRDR
              140       150       160       170           180      

            170       180       190       200       210       220  
pF1KSD DYDRKRDRDERDRSRHSSRSERDGGSERSSRRNEPESPRHRPKDAATPSRSTWEEEDSGY
       : ::.:.::.  . :: :::.   .  :. .::. .: :.: .. .    .  ...:. :
NP_004 DRDRERNRDRDHKRRHRSRSR---SRSRTRERNKVKS-RYRSRSRSQSPPKDRKDRDK-Y
        190       200          210       220        230       240  

            230             240       250       260       270      
pF1KSD GSSRRSQW-----ESPSPT-PSYRDSERSHRLSTRDRDRSVRGKYSDDTPLPTPSYKYNE
       :    ..:     . : :  :.  :   ..  :  .      : . .   :        .
NP_004 GERNLDRWRDKHVDRPPPEEPTIGDIYNGKVTSIMQF-----GCFVQLEGLRKRWEGLVH
             250       260       270            280       290      

        280       290         300       310        320       330   
pF1KSD WADDRRHLGSTPRLSR--GRGRREEGEEGISFDTEEERQQWED-DQRQADRDWYMMDEGY
        .. ::. : .  ..   ..:.: . .  .::   .   . .: ::. ..      : . 
NP_004 ISELRRE-GRVANVADVVSKGQRVKVKV-LSFTGTKTSLSMKDVDQETGE------DLNP
        300        310       320        330       340              

           340       350          360          370         380     
pF1KSD DEFHNPLAYSSEDYVRR---REQHLHKQKQKRI---SAQRRQINE--DNERWETNRMLTS
       .. .: .. ..:.   :   :  ::   .  ..   : .:.....  : :.:: ..:...
NP_004 NRRRNLVGETNEETSMRNPDRPTHLSLVSAPEVEDDSLERKRLTRISDPEKWEIKQMIAA
      350       360       370       380       390       400        

         390                  400       410       420       430    
pF1KSD GVVHRLEV---DE--------DFEEDNAAKVHLMVHNLVPPFLDGRIVFTKQPEPVIPVK
       .:. . :    ::        : :::.  ...:. ..  :::: :.   . .  :.  ::
NP_004 NVLSKEEFPDFDEETGILPKVDDEEDEDLEIELVEEE--PPFLRGHTKQSMDMSPIKIVK
      410       420       430       440         450       460      

          440       450        460               470       480     
pF1KSD DATSDLAIIARKGSQTVRKHREQKE-RKKAQ--------HKHWELAGTKLGDIMGVKKEE
       .  ..:.  :   :  ....:: :. ...:.        .:::      : :  : .   
NP_004 NPDGSLSQAAMMQSALAKERRELKQAQREAEMDSIPMGLNKHWV---DPLPDAEGRQIAA
        470       480       490       500       510          520   

         490       500       510       520       530       540     
pF1KSD EPDKAVTEDGKVDYRTEQKFADHMKRKSEASSEFAKKKSILEQRQYLPIFAVQQELLTII
       .        . .    .. :. .     .::     . ::::::. :::. ....:.  .
NP_004 NMRGIGMMPNDIPEWKKHAFGGN-----KASYGKKTQMSILEQRESLPIYKLKEQLVQAV
           530       540            550       560       570        

         550       560       570       580       590       600     
pF1KSD RDNSIVIVVGETGSGKTTQLTQYLHEDGYTDYGMIGCTQPRRVAAMSVAKRVSEEMGGNL
       .::.:.::.::::::::::.:::: : :::. : :::::::::::::::::::::.:  :
NP_004 HDNQILIVIGETGSGKTTQITQYLAEAGYTSRGKIGCTQPRRVAAMSVAKRVSEEFGCCL
      580       590       600       610       620       630        

         610       620       630       640       650       660     
pF1KSD GEEVGYAIRFEDCTSENTLIKYMTDGILLRESLREADLDHYSAIIMDEAHERSLNTDVLF
       :.::::.:::::::: .:.:::::::.:::: : . :: .:. :..::::::...:::::
NP_004 GQEVGYTIRFEDCTSPETVIKYMTDGMLLRECLIDPDLTQYAIIMLDEAHERTIHTDVLF
      640       650       660       670       680       690        

         670       680       690       700       710       720     
pF1KSD GLLREVVARRSDLKLIVTSATMDAEKFAAFFGNVPIFHIPGRTFPVDILFSKTPQEDYVE
       :::...: .:.:.::::::::.:: ::. .: ..::: :::::.::.::..: :. ::..
NP_004 GLLKKTVQKRQDMKLIVTSATLDAVKFSQYFYEAPIFTIPGRTYPVEILYTKEPETDYLD
      700       710       720       730       740       750        

         730       740       750       760        770       780    
pF1KSD AAVKQSLQVHLSGAPGDILIFMPGQEDIEVTSDQIVEHLEEL-ENAPALAVLPIYSQLPS
       :..   .:.::.  :::::.:. :::.:... . . :... :  ..: : .::.:: :::
NP_004 ASLITVMQIHLTEPPGDILVFLTGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPS
      760       770       780       790       800       810        

          790       800       810       820       830       840    
pF1KSD DLQAKIFQKAPDGVRKCIVATNIAETSLTVDGIMFVIDSGYCKLKVFNPRIGMDALQIYP
       ..:..::. :: : :: ..::::::::::.:::..:.: :. : ::.: . :.: : . :
NP_004 EMQTRIFDPAPPGSRKVVIATNIAETSLTIDGIYYVVDPGFVKQKVYNSKTGIDQLVVTP
      820       830       840       850       860       870        

          850       860       870       880       890       900    
pF1KSD ISQANANQRSGRAGRTGPGQCFRLYTQSAYKNELLTTTVPEIQRTNLANVVLLLKSLGVQ
       ::::.:.::.:::::::::.:.::::. ::..:.:::.::::::::::..:: ::..:..
NP_004 ISQAQAKQRAGRAGRTGPGKCYRLYTERAYRDEMLTTNVPEIQRTNLASTVLSLKAMGIN
      880       890       900       910       920       930        

          910       920       930       940       950       960    
pF1KSD DLLQFHFMDPPPEDNMLNSMYQLWILGALDNTGGLTSTGRLMVEFPLDPALSKMLIVSCD
       :::.: ::: :: ......: ::. :::::. : ::  :: :.::::.: : ::::.:  
NP_004 DLLSFDFMDAPPMETLITAMEQLYTLGALDDEGLLTRLGRRMAEFPLEPMLCKMLIMSVH
      940       950       960       970       980       990        

          970       980       990      1000      1010      1020    
pF1KSD MGCSSEILLIVSMLSVPAIFYRPKGREEESDQIREKFAVPESDHLTYLNVYLQWKNNNYS
       .::: :.: :::::::  .::::: ..  .:: . ::   :.:::: : :: .::::..:
NP_004 LGCSEEMLTIVSMLSVQNVFYRPKDKQALADQKKAKFHQTEGDHLTLLAVYNSWKNNKFS
     1000      1010      1020      1030      1040      1050        

         1030      1040      1050      1060      1070      1080    
pF1KSD TIWCNDHFIHAKAMRKVREVRAQLKDIMVQQRMSLASCGTDWDIVRKCICAAYFHQAAKL
       . :: ..::.:...:.....: :.  :: .......::: .   :.: ::...:..::: 
NP_004 NPWCYENFIQARSLRRAQDIRKQMLGIMDRHKLDVVSCGKSTVRVQKAICSGFFRNAAKK
     1060      1070      1080      1090      1100      1110        

         1090      1100      1110      1120      1130      1140    
pF1KSD KGIGEYVNIRTGMPCHLHPTSSLFGMGYTPDYIVYHELVMTTKEYMQCVTAVDGEWLAEL
            : ..   .  ..::.:.::.    :...::::::.::::::. ::..: .::.:.
NP_004 DPQEGYRTLIDQQVVYIHPSSALFN--RQPEWVVYHELVLTTKEYMREVTTIDPRWLVEF
     1120      1130      1140        1150      1160      1170      

         1150       1160      1170      1180      1190      1200   
pF1KSD GPMFYSVKQAGK-SRQENRRRAKEEASAMEEEMALAEEQLRARRQEQEKRSPLGSVRSTK
       .: :..:..  : :.:....: .   . .::  :                          
NP_004 APAFFKVSDPTKLSKQKKQQRLEPLYNRYEEPNAWRISRAFRRR                
       1180      1190      1200      1210      1220                

          1210      1220       
pF1KSD IYTPGRKEQGEPMAPRRTPARFGL

>>NP_001309150 (OMIM: 600396) ATP-dependent RNA helicase  (1218 aa)
 initn: 2609 init1: 1248 opt: 2537  Z-score: 1521.4  bits: 293.6 E(85289): 5.3e-78
Smith-Waterman score: 2611; 41.4% identity (69.3% similar) in 1084 aa overlap (133-1177:161-1208)

            110       120       130       140       150       160  
pF1KSD NIRKDRHYRSARVETPSHPGGVSEEFWERSRQRERERREHGVYASSKEEKDWKKEKSRDR
                                     .::. :.:      ..:.... .....:::
NP_001 RTMLDEDDVKVAVDVLKELEALMPSAAGQEKQRDAEHR------TKKKKRSRSRDRNRDR
              140       150       160             170       180    

            170       180       190       200       210       220  
pF1KSD DYDRKRDRDERDRSRHSSRSERDGGSERSSRRNEPESPRHRPKDAATPSRSTWEEEDSGY
       : ::.:.::.  . :: :::.   .  :. .::. .: :.: .. .    .  ...:. :
NP_001 DRDRERNRDRDHKRRHRSRSR---SRSRTRERNKVKS-RYRSRSRSQSPPKDRKDRDK-Y
          190       200          210        220       230          

            230             240       250       260       270      
pF1KSD GSSRRSQW-----ESPSPT-PSYRDSERSHRLSTRDRDRSVRGKYSDDTPLPTPSYKYNE
       :    ..:     . : :  :.  :   ..  :  .      : . .   :        .
NP_001 GERNLDRWRDKHVDRPPPEEPTIGDIYNGKVTSIMQF-----GCFVQLEGLRKRWEGLVH
     240       250       260       270            280       290    

        280       290         300       310        320       330   
pF1KSD WADDRRHLGSTPRLSR--GRGRREEGEEGISFDTEEERQQWED-DQRQADRDWYMMDEGY
        .. ::. : .  ..   ..:.: . .  .::   .   . .: ::. ..      : . 
NP_001 ISELRRE-GRVANVADVVSKGQRVKVKV-LSFTGTKTSLSMKDVDQETGE------DLNP
          300        310       320        330       340            

           340       350          360          370         380     
pF1KSD DEFHNPLAYSSEDYVRR---REQHLHKQKQKRI---SAQRRQINE--DNERWETNRMLTS
       .. .: .. ..:.   :   :  ::   .  ..   : .:.....  : :.:: ..:...
NP_001 NRRRNLVGETNEETSMRNPDRPTHLSLVSAPEVEDDSLERKRLTRISDPEKWEIKQMIAA
        350       360       370       380       390       400      

         390                  400       410       420       430    
pF1KSD GVVHRLEV---DE--------DFEEDNAAKVHLMVHNLVPPFLDGRIVFTKQPEPVIPVK
       .:. . :    ::        : :::.  ...:. ..  :::: :.   . .  :.  ::
NP_001 NVLSKEEFPDFDEETGILPKVDDEEDEDLEIELVEEE--PPFLRGHTKQSMDMSPIKIVK
        410       420       430       440         450       460    

          440       450        460               470       480     
pF1KSD DATSDLAIIARKGSQTVRKHREQKE-RKKAQ--------HKHWELAGTKLGDIMGVKKEE
       .  ..:.  :   :  ....:: :. ...:.        .:::      : :  : .   
NP_001 NPDGSLSQAAMMQSALAKERRELKQAQREAEMDSIPMGLNKHWV---DPLPDAEGRQIAA
          470       480       490       500          510       520 

         490       500       510       520       530       540     
pF1KSD EPDKAVTEDGKVDYRTEQKFADHMKRKSEASSEFAKKKSILEQRQYLPIFAVQQELLTII
       .        . .    .. :. .     .::     . ::::::. :::. ....:.  .
NP_001 NMRGIGMMPNDIPEWKKHAFGGN-----KASYGKKTQMSILEQRESLPIYKLKEQLVQAV
             530       540            550       560       570      

         550       560       570       580       590       600     
pF1KSD RDNSIVIVVGETGSGKTTQLTQYLHEDGYTDYGMIGCTQPRRVAAMSVAKRVSEEMGGNL
       .::.:.::.::::::::::.:::: : :::. : :::::::::::::::::::::.:  :
NP_001 HDNQILIVIGETGSGKTTQITQYLAEAGYTSRGKIGCTQPRRVAAMSVAKRVSEEFGCCL
        580       590       600       610       620       630      

         610       620       630       640       650       660     
pF1KSD GEEVGYAIRFEDCTSENTLIKYMTDGILLRESLREADLDHYSAIIMDEAHERSLNTDVLF
       :.::::.:::::::: .:.:::::::.:::: : . :: .:. :..::::::...:::::
NP_001 GQEVGYTIRFEDCTSPETVIKYMTDGMLLRECLIDPDLTQYAIIMLDEAHERTIHTDVLF
        640       650       660       670       680       690      

         670       680       690       700       710       720     
pF1KSD GLLREVVARRSDLKLIVTSATMDAEKFAAFFGNVPIFHIPGRTFPVDILFSKTPQEDYVE
       :::...: .:.:.::::::::.:: ::. .: ..::: :::::.::.::..: :. ::..
NP_001 GLLKKTVQKRQDMKLIVTSATLDAVKFSQYFYEAPIFTIPGRTYPVEILYTKEPETDYLD
        700       710       720       730       740       750      

         730       740       750       760        770       780    
pF1KSD AAVKQSLQVHLSGAPGDILIFMPGQEDIEVTSDQIVEHLEEL-ENAPALAVLPIYSQLPS
       :..   .:.::.  :::::.:. :::.:... . . :... :  ..: : .::.:: :::
NP_001 ASLITVMQIHLTEPPGDILVFLTGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPS
        760       770       780       790       800       810      

          790       800       810       820       830       840    
pF1KSD DLQAKIFQKAPDGVRKCIVATNIAETSLTVDGIMFVIDSGYCKLKVFNPRIGMDALQIYP
       ..:..::. :: : :: ..::::::::::.:::..:.: :. : ::.: . :.: : . :
NP_001 EMQTRIFDPAPPGSRKVVIATNIAETSLTIDGIYYVVDPGFVKQKVYNSKTGIDQLVVTP
        820       830       840       850       860       870      

          850       860       870       880       890       900    
pF1KSD ISQANANQRSGRAGRTGPGQCFRLYTQSAYKNELLTTTVPEIQRTNLANVVLLLKSLGVQ
       ::::.:.::.:::::::::.:.::::. ::..:.:::.::::::::::..:: ::..:..
NP_001 ISQAQAKQRAGRAGRTGPGKCYRLYTERAYRDEMLTTNVPEIQRTNLASTVLSLKAMGIN
        880       890       900       910       920       930      

          910       920       930       940       950       960    
pF1KSD DLLQFHFMDPPPEDNMLNSMYQLWILGALDNTGGLTSTGRLMVEFPLDPALSKMLIVSCD
       :::.: ::: :: ......: ::. :::::. : ::  :: :.::::.: : ::::.:  
NP_001 DLLSFDFMDAPPMETLITAMEQLYTLGALDDEGLLTRLGRRMAEFPLEPMLCKMLIMSVH
        940       950       960       970       980       990      

          970       980       990      1000      1010      1020    
pF1KSD MGCSSEILLIVSMLSVPAIFYRPKGREEESDQIREKFAVPESDHLTYLNVYLQWKNNNYS
       .::: :.: :::::::  .::::: ..  .:: . ::   :.:::: : :: .::::..:
NP_001 LGCSEEMLTIVSMLSVQNVFYRPKDKQALADQKKAKFHQTEGDHLTLLAVYNSWKNNKFS
       1000      1010      1020      1030      1040      1050      

         1030      1040      1050      1060      1070      1080    
pF1KSD TIWCNDHFIHAKAMRKVREVRAQLKDIMVQQRMSLASCGTDWDIVRKCICAAYFHQAAKL
       . :: ..::.:...:.....: :.  :: .......::: .   :.: ::...:..::: 
NP_001 NPWCYENFIQARSLRRAQDIRKQMLGIMDRHKLDVVSCGKSTVRVQKAICSGFFRNAAKK
       1060      1070      1080      1090      1100      1110      

         1090      1100      1110      1120      1130      1140    
pF1KSD KGIGEYVNIRTGMPCHLHPTSSLFGMGYTPDYIVYHELVMTTKEYMQCVTAVDGEWLAEL
            : ..   .  ..::.:.::.    :...::::::.::::::. ::..: .::.:.
NP_001 DPQEGYRTLIDQQVVYIHPSSALFN--RQPEWVVYHELVLTTKEYMREVTTIDPRWLVEF
       1120      1130      1140        1150      1160      1170    

         1150       1160      1170      1180      1190      1200   
pF1KSD GPMFYSVKQAGK-SRQENRRRAKEEASAMEEEMALAEEQLRARRQEQEKRSPLGSVRSTK
       .: :..:..  : :.:....: .   . .::  :                          
NP_001 APAFFKVSDPTKLSKQKKQQRLEPLYNRYEEPNAWRISRAFRRR                
         1180      1190      1200      1210                        

          1210      1220       
pF1KSD IYTPGRKEQGEPMAPRRTPARFGL

>>NP_001309145 (OMIM: 600396) ATP-dependent RNA helicase  (945 aa)
 initn: 2483 init1: 1248 opt: 2481  Z-score: 1489.5  bits: 287.3 E(85289): 3.1e-76
Smith-Waterman score: 2513; 47.3% identity (74.6% similar) in 838 aa overlap (364-1177:110-935)

           340       350       360       370         380       390 
pF1KSD DEFHNPLAYSSEDYVRRREQHLHKQKQKRISAQRRQINE--DNERWETNRMLTSGVVHRL
                                     : .:.....  : :.:: ..:....:. . 
NP_001 VGETNEETSMRNPDRPTHLSLVSAPEVEDDSLERKRLTRISDPEKWEIKQMIAANVLSKE
      80        90       100       110       120       130         

                        400       410       420       430       440
pF1KSD EV---DE--------DFEEDNAAKVHLMVHNLVPPFLDGRIVFTKQPEPVIPVKDATSDL
       :    ::        : :::.  ...:. ..  :::: :.   . .  :.  ::.  ..:
NP_001 EFPDFDEETGILPKVDDEEDEDLEIELVEEE--PPFLRGHTKQSMDMSPIKIVKNPDGSL
     140       150       160       170         180       190       

              450        460               470       480       490 
pF1KSD AIIARKGSQTVRKHREQKE-RKKAQ--------HKHWELAGTKLGDIMGVKKEEEPDKAV
       .  :   :  ....:: :. ...:.        .:::      : :  : .   .     
NP_001 SQAAMMQSALAKERRELKQAQREAEMDSIPMGLNKHWV---DPLPDAEGRQIAANMRGIG
       200       210       220       230          240       250    

             500       510       520       530       540       550 
pF1KSD TEDGKVDYRTEQKFADHMKRKSEASSEFAKKKSILEQRQYLPIFAVQQELLTIIRDNSIV
          . .    .. :. .     .::     . ::::::. :::. ....:.  ..::.:.
NP_001 MMPNDIPEWKKHAFGGN-----KASYGKKTQMSILEQRESLPIYKLKEQLVQAVHDNQIL
          260       270            280       290       300         

             560       570       580       590       600       610 
pF1KSD IVVGETGSGKTTQLTQYLHEDGYTDYGMIGCTQPRRVAAMSVAKRVSEEMGGNLGEEVGY
       ::.::::::::::.:::: : :::. : :::::::::::::::::::::.:  ::.::::
NP_001 IVIGETGSGKTTQITQYLAEAGYTSRGKIGCTQPRRVAAMSVAKRVSEEFGCCLGQEVGY
     310       320       330       340       350       360         

             620       630       640       650       660       670 
pF1KSD AIRFEDCTSENTLIKYMTDGILLRESLREADLDHYSAIIMDEAHERSLNTDVLFGLLREV
       .:::::::: .:.:::::::.:::: : . :: .:. :..::::::...::::::::...
NP_001 TIRFEDCTSPETVIKYMTDGMLLRECLIDPDLTQYAIIMLDEAHERTIHTDVLFGLLKKT
     370       380       390       400       410       420         

             680       690       700       710       720       730 
pF1KSD VARRSDLKLIVTSATMDAEKFAAFFGNVPIFHIPGRTFPVDILFSKTPQEDYVEAAVKQS
       : .:.:.::::::::.:: ::. .: ..::: :::::.::.::..: :. ::..:..   
NP_001 VQKRQDMKLIVTSATLDAVKFSQYFYEAPIFTIPGRTYPVEILYTKEPETDYLDASLITV
     430       440       450       460       470       480         

             740       750       760        770       780       790
pF1KSD LQVHLSGAPGDILIFMPGQEDIEVTSDQIVEHLEEL-ENAPALAVLPIYSQLPSDLQAKI
       .:.::.  :::::.:. :::.:... . . :... :  ..: : .::.:: :::..:..:
NP_001 MQIHLTEPPGDILVFLTGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPSEMQTRI
     490       500       510       520       530       540         

              800       810       820       830       840       850
pF1KSD FQKAPDGVRKCIVATNIAETSLTVDGIMFVIDSGYCKLKVFNPRIGMDALQIYPISQANA
       :. :: : :: ..::::::::::.:::..:.: :. : ::.: . :.: : . :::::.:
NP_001 FDPAPPGSRKVVIATNIAETSLTIDGIYYVVDPGFVKQKVYNSKTGIDQLVVTPISQAQA
     550       560       570       580       590       600         

              860       870       880       890       900       910
pF1KSD NQRSGRAGRTGPGQCFRLYTQSAYKNELLTTTVPEIQRTNLANVVLLLKSLGVQDLLQFH
       .::.:::::::::.:.::::. ::..:.:::.::::::::::..:: ::..:..:::.: 
NP_001 KQRAGRAGRTGPGKCYRLYTERAYRDEMLTTNVPEIQRTNLASTVLSLKAMGINDLLSFD
     610       620       630       640       650       660         

              920       930       940       950       960       970
pF1KSD FMDPPPEDNMLNSMYQLWILGALDNTGGLTSTGRLMVEFPLDPALSKMLIVSCDMGCSSE
       ::: :: ......: ::. :::::. : ::  :: :.::::.: : ::::.:  .::: :
NP_001 FMDAPPMETLITAMEQLYTLGALDDEGLLTRLGRRMAEFPLEPMLCKMLIMSVHLGCSEE
     670       680       690       700       710       720         

              980       990      1000      1010      1020      1030
pF1KSD ILLIVSMLSVPAIFYRPKGREEESDQIREKFAVPESDHLTYLNVYLQWKNNNYSTIWCND
       .: :::::::  .::::: ..  .:: . ::   :.:::: : :: .::::..:. :: .
NP_001 MLTIVSMLSVQNVFYRPKDKQALADQKKAKFHQTEGDHLTLLAVYNSWKNNKFSNPWCYE
     730       740       750       760       770       780         

             1040      1050      1060      1070      1080      1090
pF1KSD HFIHAKAMRKVREVRAQLKDIMVQQRMSLASCGTDWDIVRKCICAAYFHQAAKLKGIGEY
       .::.:...:.....: :.  :: .......::: .   :.: ::...:..:::      :
NP_001 NFIQARSLRRAQDIRKQMLGIMDRHKLDVVSCGKSTVRVQKAICSGFFRNAAKKDPQEGY
     790       800       810       820       830       840         

             1100      1110      1120      1130      1140      1150
pF1KSD VNIRTGMPCHLHPTSSLFGMGYTPDYIVYHELVMTTKEYMQCVTAVDGEWLAELGPMFYS
        ..   .  ..::.:.::.    :...::::::.::::::. ::..: .::.:..: :..
NP_001 RTLIDQQVVYIHPSSALFN--RQPEWVVYHELVLTTKEYMREVTTIDPRWLVEFAPAFFK
     850       860         870       880       890       900       

              1160      1170      1180      1190      1200         
pF1KSD VKQAGK-SRQENRRRAKEEASAMEEEMALAEEQLRARRQEQEKRSPLGSVRSTKIYTPGR
       :..  : :.:....: .   . .::  :                                
NP_001 VSDPTKLSKQKKQQRLEPLYNRYEEPNAWRISRAFRRR                      
       910       920       930       940                           

>>NP_001309148 (OMIM: 600396) ATP-dependent RNA helicase  (1169 aa)
 initn: 2437 init1: 1248 opt: 2374  Z-score: 1425.0  bits: 275.7 E(85289): 1.2e-72
Smith-Waterman score: 2446; 41.2% identity (68.9% similar) in 1025 aa overlap (133-1119:161-1151)

            110       120       130       140       150       160  
pF1KSD NIRKDRHYRSARVETPSHPGGVSEEFWERSRQRERERREHGVYASSKEEKDWKKEKSRDR
                                     .::. :.:..    ..:.... .....:::
NP_001 RTMLDEDDVKVAVDVLKELEALMPSAAGQEKQRDAEHRDR----TKKKKRSRSRDRNRDR
              140       150       160       170           180      

            170       180       190       200       210       220  
pF1KSD DYDRKRDRDERDRSRHSSRSERDGGSERSSRRNEPESPRHRPKDAATPSRSTWEEEDSGY
       : ::.:.::.  . :: :::.   .  :. .::. .: :.: .. .    .  ...:. :
NP_001 DRDRERNRDRDHKRRHRSRSR---SRSRTRERNKVKS-RYRSRSRSQSPPKDRKDRDK-Y
        190       200          210       220        230       240  

            230             240       250       260       270      
pF1KSD GSSRRSQW-----ESPSPT-PSYRDSERSHRLSTRDRDRSVRGKYSDDTPLPTPSYKYNE
       :    ..:     . : :  :.  :   ..  :  .      : . .   :        .
NP_001 GERNLDRWRDKHVDRPPPEEPTIGDIYNGKVTSIMQF-----GCFVQLEGLRKRWEGLVH
             250       260       270            280       290      

        280       290         300       310        320       330   
pF1KSD WADDRRHLGSTPRLSR--GRGRREEGEEGISFDTEEERQQWED-DQRQADRDWYMMDEGY
        .. ::. : .  ..   ..:.: .  . .::   .   . .: ::. ..      : . 
NP_001 ISELRRE-GRVANVADVVSKGQRVK-VKVLSFTGTKTSLSMKDVDQETGE------DLNP
        300        310       320        330       340              

           340       350          360          370         380     
pF1KSD DEFHNPLAYSSEDYVRR---REQHLHKQKQKRI---SAQRRQINE--DNERWETNRMLTS
       .. .: .. ..:.   :   :  ::   .  ..   : .:.....  : :.:: ..:...
NP_001 NRRRNLVGETNEETSMRNPDRPTHLSLVSAPEVEDDSLERKRLTRISDPEKWEIKQMIAA
      350       360       370       380       390       400        

         390                  400       410       420       430    
pF1KSD GVVHRLEV---DE--------DFEEDNAAKVHLMVHNLVPPFLDGRIVFTKQPEPVIPVK
       .:. . :    ::        : :::.  ...:. ..  :::: :.   . .  :.  ::
NP_001 NVLSKEEFPDFDEETGILPKVDDEEDEDLEIELVEEE--PPFLRGHTKQSMDMSPIKIVK
      410       420       430       440         450       460      

          440       450        460               470       480     
pF1KSD DATSDLAIIARKGSQTVRKHREQKE-RKKAQ--------HKHWELAGTKLGDIMGVKKEE
       .  ..:.  :   :  ....:: :. ...:.        .:::      : :  : .   
NP_001 NPDGSLSQAAMMQSALAKERRELKQAQREAEMDSIPMGLNKHWV---DPLPDAEGRQIAA
        470       480       490       500       510          520   

         490       500       510       520       530       540     
pF1KSD EPDKAVTEDGKVDYRTEQKFADHMKRKSEASSEFAKKKSILEQRQYLPIFAVQQELLTII
       .        . .    .. :. .     .::     . ::::::. :::. ....:.  .
NP_001 NMRGIGMMPNDIPEWKKHAFGGN-----KASYGKKTQMSILEQRESLPIYKLKEQLVQAV
           530       540            550       560       570        

         550       560       570       580       590       600     
pF1KSD RDNSIVIVVGETGSGKTTQLTQYLHEDGYTDYGMIGCTQPRRVAAMSVAKRVSEEMGGNL
       .::.:.::.::::::::::.:::: : :::. : :::::::::::::::::::::.:  :
NP_001 HDNQILIVIGETGSGKTTQITQYLAEAGYTSRGKIGCTQPRRVAAMSVAKRVSEEFGCCL
      580       590       600       610       620       630        

         610       620       630       640       650       660     
pF1KSD GEEVGYAIRFEDCTSENTLIKYMTDGILLRESLREADLDHYSAIIMDEAHERSLNTDVLF
       :.::::.:::::::: .:.:::::::.:::: : . :: .:. :..::::::...:::::
NP_001 GQEVGYTIRFEDCTSPETVIKYMTDGMLLRECLIDPDLTQYAIIMLDEAHERTIHTDVLF
      640       650       660       670       680       690        

         670       680       690       700       710       720     
pF1KSD GLLREVVARRSDLKLIVTSATMDAEKFAAFFGNVPIFHIPGRTFPVDILFSKTPQEDYVE
       :::...: .:.:.::::::::.:: ::. .: ..::: :::::.::.::..: :. ::..
NP_001 GLLKKTVQKRQDMKLIVTSATLDAVKFSQYFYEAPIFTIPGRTYPVEILYTKEPETDYLD
      700       710       720       730       740       750        

         730       740       750       760        770       780    
pF1KSD AAVKQSLQVHLSGAPGDILIFMPGQEDIEVTSDQIVEHLEEL-ENAPALAVLPIYSQLPS
       :..   .:.::.  :::::.:. :::.:... . . :... :  ..: : .::.:: :::
NP_001 ASLITVMQIHLTEPPGDILVFLTGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPS
      760       770       780       790       800       810        

          790       800       810       820       830       840    
pF1KSD DLQAKIFQKAPDGVRKCIVATNIAETSLTVDGIMFVIDSGYCKLKVFNPRIGMDALQIYP
       ..:..::. :: : :: ..::::::::::.:::..:.: :. : ::.: . :.: : . :
NP_001 EMQTRIFDPAPPGSRKVVIATNIAETSLTIDGIYYVVDPGFVKQKVYNSKTGIDQLVVTP
      820       830       840       850       860       870        

          850       860       870       880       890       900    
pF1KSD ISQANANQRSGRAGRTGPGQCFRLYTQSAYKNELLTTTVPEIQRTNLANVVLLLKSLGVQ
       ::::.:.::.:::::::::.:.::::. ::..:.:::.::::::::::..:: ::..:..
NP_001 ISQAQAKQRAGRAGRTGPGKCYRLYTERAYRDEMLTTNVPEIQRTNLASTVLSLKAMGIN
      880       890       900       910       920       930        

          910       920       930       940       950       960    
pF1KSD DLLQFHFMDPPPEDNMLNSMYQLWILGALDNTGGLTSTGRLMVEFPLDPALSKMLIVSCD
       :::.: ::: :: ......: ::. :::::. : ::  :: :.::::.: : ::::.:  
NP_001 DLLSFDFMDAPPMETLITAMEQLYTLGALDDEGLLTRLGRRMAEFPLEPMLCKMLIMSVH
      940       950       960       970       980       990        

          970       980       990      1000      1010      1020    
pF1KSD MGCSSEILLIVSMLSVPAIFYRPKGREEESDQIREKFAVPESDHLTYLNVYLQWKNNNYS
       .::: :.: :::::::  .::::: ..  .:: . ::   :.:::: : :: .::::..:
NP_001 LGCSEEMLTIVSMLSVQNVFYRPKDKQALADQKKAKFHQTEGDHLTLLAVYNSWKNNKFS
     1000      1010      1020      1030      1040      1050        

         1030      1040      1050      1060      1070      1080    
pF1KSD TIWCNDHFIHAKAMRKVREVRAQLKDIMVQQRMSLASCGTDWDIVRKCICAAYFHQAAKL
       . :: ..::.:...:.....: :.  :: .......::: .   :.: ::...:..::: 
NP_001 NPWCYENFIQARSLRRAQDIRKQMLGIMDRHKLDVVSCGKSTVRVQKAICSGFFRNAAKK
     1060      1070      1080      1090      1100      1110        

         1090      1100      1110      1120      1130      1140    
pF1KSD KGIGEYVNIRTGMPCHLHPTSSLFGMGYTPDYIVYHELVMTTKEYMQCVTAVDGEWLAEL
            : ..   .  ..::.:.::.    :.. .:                         
NP_001 DPQEGYRTLIDQQVVYIHPSSALFN--RQPEWDLYSRFSEWKSGTNCSSLSGT       
     1120      1130      1140        1150      1160                

         1150      1160      1170      1180      1190      1200    
pF1KSD GPMFYSVKQAGKSRQENRRRAKEEASAMEEEMALAEEQLRARRQEQEKRSPLGSVRSTKI




1227 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 00:48:28 2016 done: Thu Nov  3 00:48:30 2016
 Total Scan time: 14.540 Total Display time:  0.480

Function used was FASTA [36.3.4 Apr, 2011]
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