Result of FASTA (omim) for pF1KSDA0210
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KSDA0210, 795 aa
  1>>>pF1KSDA0210 795 - 795 aa - 795 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.8423+/-0.000372; mu= 9.4726+/- 0.023
 mean_var=153.3255+/-31.707, 0's: 0 Z-trim(118.0): 59  B-trim: 761 in 1/54
 Lambda= 0.103578
 statistics sampled from 30427 (30490) to 30427 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.699), E-opt: 0.2 (0.357), width:  16
 Scan time: 10.280

The best scores are:                                      opt bits E(85289)
XP_005265671 (OMIM: 615740) PREDICTED: TBC1 domain ( 795) 5283 801.8       0
XP_016863048 (OMIM: 615740) PREDICTED: TBC1 domain ( 795) 5283 801.8       0
XP_016863049 (OMIM: 615740) PREDICTED: TBC1 domain ( 795) 5283 801.8       0
XP_016863050 (OMIM: 615740) PREDICTED: TBC1 domain ( 795) 5283 801.8       0
NP_055559 (OMIM: 615740) TBC1 domain family member ( 795) 5283 801.8       0
XP_016863046 (OMIM: 615740) PREDICTED: TBC1 domain ( 795) 5283 801.8       0
XP_016863047 (OMIM: 615740) PREDICTED: TBC1 domain ( 795) 5283 801.8       0
XP_016863053 (OMIM: 615740) PREDICTED: TBC1 domain ( 659) 4362 664.1 5.4e-190
XP_016863054 (OMIM: 615740) PREDICTED: TBC1 domain ( 659) 4362 664.1 5.4e-190
XP_016863052 (OMIM: 615740) PREDICTED: TBC1 domain ( 659) 4362 664.1 5.4e-190
XP_016863056 (OMIM: 615740) PREDICTED: TBC1 domain ( 659) 4362 664.1 5.4e-190
XP_016863055 (OMIM: 615740) PREDICTED: TBC1 domain ( 659) 4362 664.1 5.4e-190
XP_016863042 (OMIM: 615740) PREDICTED: TBC1 domain ( 817) 3576 546.7 1.5e-154
XP_016863041 (OMIM: 615740) PREDICTED: TBC1 domain ( 817) 3576 546.7 1.5e-154
XP_011532586 (OMIM: 615740) PREDICTED: TBC1 domain ( 817) 3576 546.7 1.5e-154
XP_016863045 (OMIM: 615740) PREDICTED: TBC1 domain ( 817) 3576 546.7 1.5e-154
XP_011532583 (OMIM: 615740) PREDICTED: TBC1 domain ( 817) 3576 546.7 1.5e-154
XP_005265668 (OMIM: 615740) PREDICTED: TBC1 domain ( 817) 3576 546.7 1.5e-154
XP_006713493 (OMIM: 615740) PREDICTED: TBC1 domain ( 817) 3576 546.7 1.5e-154
XP_016863043 (OMIM: 615740) PREDICTED: TBC1 domain ( 817) 3576 546.7 1.5e-154
XP_016863044 (OMIM: 615740) PREDICTED: TBC1 domain ( 817) 3576 546.7 1.5e-154
NP_001127853 (OMIM: 615740) TBC1 domain family mem ( 817) 3576 546.7 1.5e-154
XP_005265669 (OMIM: 615740) PREDICTED: TBC1 domain ( 817) 3576 546.7 1.5e-154
XP_011532585 (OMIM: 615740) PREDICTED: TBC1 domain ( 817) 3576 546.7 1.5e-154
XP_011532588 (OMIM: 615740) PREDICTED: TBC1 domain ( 817) 3576 546.7 1.5e-154
XP_016863057 (OMIM: 615740) PREDICTED: TBC1 domain ( 444) 3008 461.7 3.2e-129
XP_011532589 (OMIM: 615740) PREDICTED: TBC1 domain ( 681) 2655 409.0 3.4e-113
XP_016863051 (OMIM: 615740) PREDICTED: TBC1 domain ( 681) 2655 409.0 3.4e-113
XP_005265673 (OMIM: 615740) PREDICTED: TBC1 domain ( 681) 2655 409.0 3.4e-113
XP_005265672 (OMIM: 615740) PREDICTED: TBC1 domain ( 681) 2655 409.0 3.4e-113
XP_005252117 (OMIM: 616218) PREDICTED: TBC1 domain ( 324)  272 52.7 2.9e-06
NP_060671 (OMIM: 616218) TBC1 domain family member ( 400)  272 52.8 3.4e-06
NP_001273701 (OMIM: 616218) TBC1 domain family mem ( 275)  223 45.4 0.00041
XP_016884231 (OMIM: 616879) PREDICTED: TBC1 domain ( 549)  225 45.9 0.00058


>>XP_005265671 (OMIM: 615740) PREDICTED: TBC1 domain fam  (795 aa)
 initn: 5283 init1: 5283 opt: 5283  Z-score: 4274.6  bits: 801.8 E(85289):    0
Smith-Waterman score: 5283; 100.0% identity (100.0% similar) in 795 aa overlap (1-795:1-795)

               10        20        30        40        50        60
pF1KSD MYHSLSETRHPLQPEEQEVGIDPLSSYSNKSGGDSNKNGRRTSSTLDSEGTFNSYRKEWE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MYHSLSETRHPLQPEEQEVGIDPLSSYSNKSGGDSNKNGRRTSSTLDSEGTFNSYRKEWE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD ELFVNNNYLATIRQKGINGQLRSSRFRSICWKLFLCVLPQDKSQWISRIEELRAWYSNIK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELFVNNNYLATIRQKGINGQLRSSRFRSICWKLFLCVLPQDKSQWISRIEELRAWYSNIK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD EIHITNPRKVVGQQDLMINNPLSQDEGSLWNKFFQDKELRSMIEQDVKRTFPEMQFFQQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EIHITNPRKVVGQQDLMINNPLSQDEGSLWNKFFQDKELRSMIEQDVKRTFPEMQFFQQE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD NVRKILTDVLFCYARENEQLLYKQGMHELLAPIVFVLHCDHQAFLHASESAQPSEEMKTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NVRKILTDVLFCYARENEQLLYKQGMHELLAPIVFVLHCDHQAFLHASESAQPSEEMKTV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD LNPEYLEHDAYAVFSQLMETAEPWFSTFEHDGQKGKETLMTPIPFARPQDLGPTIAIVTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LNPEYLEHDAYAVFSQLMETAEPWFSTFEHDGQKGKETLMTPIPFARPQDLGPTIAIVTK
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD VNQIQDHLLKKHDIELYMHLNRLEIAPQIYGLRWVRLLFGREFPLQDLLVVWDALFADGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VNQIQDHLLKKHDIELYMHLNRLEIAPQIYGLRWVRLLFGREFPLQDLLVVWDALFADGL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD SLGLVDYIFVAMLLYIRDALISSNYQTCLGLLMHYPFIGDVHSLILKALFLRDPKRNPRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLGLVDYIFVAMLLYIRDALISSNYQTCLGLLMHYPFIGDVHSLILKALFLRDPKRNPRP
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD VTYQFHPNLDYYKARGADLMNKSRTNAKGAPLNINKVSNSLINFGRKLISPAMAPGSAGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VTYQFHPNLDYYKARGADLMNKSRTNAKGAPLNINKVSNSLINFGRKLISPAMAPGSAGG
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD PVPGGNSSSSSSVVIPTRTSAEAPSHHLQQQQQQQRLMKSESMPVQLNKGLSSKNISSSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PVPGGNSSSSSSVVIPTRTSAEAPSHHLQQQQQQQRLMKSESMPVQLNKGLSSKNISSSP
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD SVESLPGGREFTGSPPSSATKKDSFFSNISRSRSHSKTMGRKESEEELEAQISFLQGQLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SVESLPGGREFTGSPPSSATKKDSFFSNISRSRSHSKTMGRKESEEELEAQISFLQGQLN
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD DLDAMCKYCAKVMDTHLVNIQDVILQENLEKEDQILVSLAGLKQIKDILKGSLRFNQSQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DLDAMCKYCAKVMDTHLVNIQDVILQENLEKEDQILVSLAGLKQIKDILKGSLRFNQSQL
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD EAEENEQITIADNHYCSSGQGQGRGQGQSVQMSGAIKQASSETPGCTDRGNSDDFILISK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EAEENEQITIADNHYCSSGQGQGRGQGQSVQMSGAIKQASSETPGCTDRGNSDDFILISK
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD DDDGSSARGSFSGQAQPLRTLRSTSGKSQAPVCSPLVFSDPLMGPASASSSNPSSSPDDD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DDDGSSARGSFSGQAQPLRTLRSTSGKSQAPVCSPLVFSDPLMGPASASSSNPSSSPDDD
              730       740       750       760       770       780

              790     
pF1KSD SSKDSGFTIVSPLDI
       :::::::::::::::
XP_005 SSKDSGFTIVSPLDI
              790     

>>XP_016863048 (OMIM: 615740) PREDICTED: TBC1 domain fam  (795 aa)
 initn: 5283 init1: 5283 opt: 5283  Z-score: 4274.6  bits: 801.8 E(85289):    0
Smith-Waterman score: 5283; 100.0% identity (100.0% similar) in 795 aa overlap (1-795:1-795)

               10        20        30        40        50        60
pF1KSD MYHSLSETRHPLQPEEQEVGIDPLSSYSNKSGGDSNKNGRRTSSTLDSEGTFNSYRKEWE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MYHSLSETRHPLQPEEQEVGIDPLSSYSNKSGGDSNKNGRRTSSTLDSEGTFNSYRKEWE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD ELFVNNNYLATIRQKGINGQLRSSRFRSICWKLFLCVLPQDKSQWISRIEELRAWYSNIK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELFVNNNYLATIRQKGINGQLRSSRFRSICWKLFLCVLPQDKSQWISRIEELRAWYSNIK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD EIHITNPRKVVGQQDLMINNPLSQDEGSLWNKFFQDKELRSMIEQDVKRTFPEMQFFQQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EIHITNPRKVVGQQDLMINNPLSQDEGSLWNKFFQDKELRSMIEQDVKRTFPEMQFFQQE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD NVRKILTDVLFCYARENEQLLYKQGMHELLAPIVFVLHCDHQAFLHASESAQPSEEMKTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NVRKILTDVLFCYARENEQLLYKQGMHELLAPIVFVLHCDHQAFLHASESAQPSEEMKTV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD LNPEYLEHDAYAVFSQLMETAEPWFSTFEHDGQKGKETLMTPIPFARPQDLGPTIAIVTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNPEYLEHDAYAVFSQLMETAEPWFSTFEHDGQKGKETLMTPIPFARPQDLGPTIAIVTK
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD VNQIQDHLLKKHDIELYMHLNRLEIAPQIYGLRWVRLLFGREFPLQDLLVVWDALFADGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNQIQDHLLKKHDIELYMHLNRLEIAPQIYGLRWVRLLFGREFPLQDLLVVWDALFADGL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD SLGLVDYIFVAMLLYIRDALISSNYQTCLGLLMHYPFIGDVHSLILKALFLRDPKRNPRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLGLVDYIFVAMLLYIRDALISSNYQTCLGLLMHYPFIGDVHSLILKALFLRDPKRNPRP
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD VTYQFHPNLDYYKARGADLMNKSRTNAKGAPLNINKVSNSLINFGRKLISPAMAPGSAGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTYQFHPNLDYYKARGADLMNKSRTNAKGAPLNINKVSNSLINFGRKLISPAMAPGSAGG
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD PVPGGNSSSSSSVVIPTRTSAEAPSHHLQQQQQQQRLMKSESMPVQLNKGLSSKNISSSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVPGGNSSSSSSVVIPTRTSAEAPSHHLQQQQQQQRLMKSESMPVQLNKGLSSKNISSSP
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD SVESLPGGREFTGSPPSSATKKDSFFSNISRSRSHSKTMGRKESEEELEAQISFLQGQLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVESLPGGREFTGSPPSSATKKDSFFSNISRSRSHSKTMGRKESEEELEAQISFLQGQLN
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD DLDAMCKYCAKVMDTHLVNIQDVILQENLEKEDQILVSLAGLKQIKDILKGSLRFNQSQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLDAMCKYCAKVMDTHLVNIQDVILQENLEKEDQILVSLAGLKQIKDILKGSLRFNQSQL
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD EAEENEQITIADNHYCSSGQGQGRGQGQSVQMSGAIKQASSETPGCTDRGNSDDFILISK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAEENEQITIADNHYCSSGQGQGRGQGQSVQMSGAIKQASSETPGCTDRGNSDDFILISK
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD DDDGSSARGSFSGQAQPLRTLRSTSGKSQAPVCSPLVFSDPLMGPASASSSNPSSSPDDD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDDGSSARGSFSGQAQPLRTLRSTSGKSQAPVCSPLVFSDPLMGPASASSSNPSSSPDDD
              730       740       750       760       770       780

              790     
pF1KSD SSKDSGFTIVSPLDI
       :::::::::::::::
XP_016 SSKDSGFTIVSPLDI
              790     

>>XP_016863049 (OMIM: 615740) PREDICTED: TBC1 domain fam  (795 aa)
 initn: 5283 init1: 5283 opt: 5283  Z-score: 4274.6  bits: 801.8 E(85289):    0
Smith-Waterman score: 5283; 100.0% identity (100.0% similar) in 795 aa overlap (1-795:1-795)

               10        20        30        40        50        60
pF1KSD MYHSLSETRHPLQPEEQEVGIDPLSSYSNKSGGDSNKNGRRTSSTLDSEGTFNSYRKEWE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MYHSLSETRHPLQPEEQEVGIDPLSSYSNKSGGDSNKNGRRTSSTLDSEGTFNSYRKEWE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD ELFVNNNYLATIRQKGINGQLRSSRFRSICWKLFLCVLPQDKSQWISRIEELRAWYSNIK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELFVNNNYLATIRQKGINGQLRSSRFRSICWKLFLCVLPQDKSQWISRIEELRAWYSNIK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD EIHITNPRKVVGQQDLMINNPLSQDEGSLWNKFFQDKELRSMIEQDVKRTFPEMQFFQQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EIHITNPRKVVGQQDLMINNPLSQDEGSLWNKFFQDKELRSMIEQDVKRTFPEMQFFQQE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD NVRKILTDVLFCYARENEQLLYKQGMHELLAPIVFVLHCDHQAFLHASESAQPSEEMKTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NVRKILTDVLFCYARENEQLLYKQGMHELLAPIVFVLHCDHQAFLHASESAQPSEEMKTV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD LNPEYLEHDAYAVFSQLMETAEPWFSTFEHDGQKGKETLMTPIPFARPQDLGPTIAIVTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNPEYLEHDAYAVFSQLMETAEPWFSTFEHDGQKGKETLMTPIPFARPQDLGPTIAIVTK
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD VNQIQDHLLKKHDIELYMHLNRLEIAPQIYGLRWVRLLFGREFPLQDLLVVWDALFADGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNQIQDHLLKKHDIELYMHLNRLEIAPQIYGLRWVRLLFGREFPLQDLLVVWDALFADGL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD SLGLVDYIFVAMLLYIRDALISSNYQTCLGLLMHYPFIGDVHSLILKALFLRDPKRNPRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLGLVDYIFVAMLLYIRDALISSNYQTCLGLLMHYPFIGDVHSLILKALFLRDPKRNPRP
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD VTYQFHPNLDYYKARGADLMNKSRTNAKGAPLNINKVSNSLINFGRKLISPAMAPGSAGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTYQFHPNLDYYKARGADLMNKSRTNAKGAPLNINKVSNSLINFGRKLISPAMAPGSAGG
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD PVPGGNSSSSSSVVIPTRTSAEAPSHHLQQQQQQQRLMKSESMPVQLNKGLSSKNISSSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVPGGNSSSSSSVVIPTRTSAEAPSHHLQQQQQQQRLMKSESMPVQLNKGLSSKNISSSP
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD SVESLPGGREFTGSPPSSATKKDSFFSNISRSRSHSKTMGRKESEEELEAQISFLQGQLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVESLPGGREFTGSPPSSATKKDSFFSNISRSRSHSKTMGRKESEEELEAQISFLQGQLN
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD DLDAMCKYCAKVMDTHLVNIQDVILQENLEKEDQILVSLAGLKQIKDILKGSLRFNQSQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLDAMCKYCAKVMDTHLVNIQDVILQENLEKEDQILVSLAGLKQIKDILKGSLRFNQSQL
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD EAEENEQITIADNHYCSSGQGQGRGQGQSVQMSGAIKQASSETPGCTDRGNSDDFILISK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAEENEQITIADNHYCSSGQGQGRGQGQSVQMSGAIKQASSETPGCTDRGNSDDFILISK
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD DDDGSSARGSFSGQAQPLRTLRSTSGKSQAPVCSPLVFSDPLMGPASASSSNPSSSPDDD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDDGSSARGSFSGQAQPLRTLRSTSGKSQAPVCSPLVFSDPLMGPASASSSNPSSSPDDD
              730       740       750       760       770       780

              790     
pF1KSD SSKDSGFTIVSPLDI
       :::::::::::::::
XP_016 SSKDSGFTIVSPLDI
              790     

>>XP_016863050 (OMIM: 615740) PREDICTED: TBC1 domain fam  (795 aa)
 initn: 5283 init1: 5283 opt: 5283  Z-score: 4274.6  bits: 801.8 E(85289):    0
Smith-Waterman score: 5283; 100.0% identity (100.0% similar) in 795 aa overlap (1-795:1-795)

               10        20        30        40        50        60
pF1KSD MYHSLSETRHPLQPEEQEVGIDPLSSYSNKSGGDSNKNGRRTSSTLDSEGTFNSYRKEWE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MYHSLSETRHPLQPEEQEVGIDPLSSYSNKSGGDSNKNGRRTSSTLDSEGTFNSYRKEWE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD ELFVNNNYLATIRQKGINGQLRSSRFRSICWKLFLCVLPQDKSQWISRIEELRAWYSNIK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELFVNNNYLATIRQKGINGQLRSSRFRSICWKLFLCVLPQDKSQWISRIEELRAWYSNIK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD EIHITNPRKVVGQQDLMINNPLSQDEGSLWNKFFQDKELRSMIEQDVKRTFPEMQFFQQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EIHITNPRKVVGQQDLMINNPLSQDEGSLWNKFFQDKELRSMIEQDVKRTFPEMQFFQQE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD NVRKILTDVLFCYARENEQLLYKQGMHELLAPIVFVLHCDHQAFLHASESAQPSEEMKTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NVRKILTDVLFCYARENEQLLYKQGMHELLAPIVFVLHCDHQAFLHASESAQPSEEMKTV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD LNPEYLEHDAYAVFSQLMETAEPWFSTFEHDGQKGKETLMTPIPFARPQDLGPTIAIVTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNPEYLEHDAYAVFSQLMETAEPWFSTFEHDGQKGKETLMTPIPFARPQDLGPTIAIVTK
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD VNQIQDHLLKKHDIELYMHLNRLEIAPQIYGLRWVRLLFGREFPLQDLLVVWDALFADGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNQIQDHLLKKHDIELYMHLNRLEIAPQIYGLRWVRLLFGREFPLQDLLVVWDALFADGL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD SLGLVDYIFVAMLLYIRDALISSNYQTCLGLLMHYPFIGDVHSLILKALFLRDPKRNPRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLGLVDYIFVAMLLYIRDALISSNYQTCLGLLMHYPFIGDVHSLILKALFLRDPKRNPRP
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD VTYQFHPNLDYYKARGADLMNKSRTNAKGAPLNINKVSNSLINFGRKLISPAMAPGSAGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTYQFHPNLDYYKARGADLMNKSRTNAKGAPLNINKVSNSLINFGRKLISPAMAPGSAGG
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD PVPGGNSSSSSSVVIPTRTSAEAPSHHLQQQQQQQRLMKSESMPVQLNKGLSSKNISSSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVPGGNSSSSSSVVIPTRTSAEAPSHHLQQQQQQQRLMKSESMPVQLNKGLSSKNISSSP
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD SVESLPGGREFTGSPPSSATKKDSFFSNISRSRSHSKTMGRKESEEELEAQISFLQGQLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVESLPGGREFTGSPPSSATKKDSFFSNISRSRSHSKTMGRKESEEELEAQISFLQGQLN
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD DLDAMCKYCAKVMDTHLVNIQDVILQENLEKEDQILVSLAGLKQIKDILKGSLRFNQSQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLDAMCKYCAKVMDTHLVNIQDVILQENLEKEDQILVSLAGLKQIKDILKGSLRFNQSQL
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD EAEENEQITIADNHYCSSGQGQGRGQGQSVQMSGAIKQASSETPGCTDRGNSDDFILISK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAEENEQITIADNHYCSSGQGQGRGQGQSVQMSGAIKQASSETPGCTDRGNSDDFILISK
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD DDDGSSARGSFSGQAQPLRTLRSTSGKSQAPVCSPLVFSDPLMGPASASSSNPSSSPDDD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDDGSSARGSFSGQAQPLRTLRSTSGKSQAPVCSPLVFSDPLMGPASASSSNPSSSPDDD
              730       740       750       760       770       780

              790     
pF1KSD SSKDSGFTIVSPLDI
       :::::::::::::::
XP_016 SSKDSGFTIVSPLDI
              790     

>>NP_055559 (OMIM: 615740) TBC1 domain family member 5 i  (795 aa)
 initn: 5283 init1: 5283 opt: 5283  Z-score: 4274.6  bits: 801.8 E(85289):    0
Smith-Waterman score: 5283; 100.0% identity (100.0% similar) in 795 aa overlap (1-795:1-795)

               10        20        30        40        50        60
pF1KSD MYHSLSETRHPLQPEEQEVGIDPLSSYSNKSGGDSNKNGRRTSSTLDSEGTFNSYRKEWE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MYHSLSETRHPLQPEEQEVGIDPLSSYSNKSGGDSNKNGRRTSSTLDSEGTFNSYRKEWE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD ELFVNNNYLATIRQKGINGQLRSSRFRSICWKLFLCVLPQDKSQWISRIEELRAWYSNIK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ELFVNNNYLATIRQKGINGQLRSSRFRSICWKLFLCVLPQDKSQWISRIEELRAWYSNIK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD EIHITNPRKVVGQQDLMINNPLSQDEGSLWNKFFQDKELRSMIEQDVKRTFPEMQFFQQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EIHITNPRKVVGQQDLMINNPLSQDEGSLWNKFFQDKELRSMIEQDVKRTFPEMQFFQQE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD NVRKILTDVLFCYARENEQLLYKQGMHELLAPIVFVLHCDHQAFLHASESAQPSEEMKTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 NVRKILTDVLFCYARENEQLLYKQGMHELLAPIVFVLHCDHQAFLHASESAQPSEEMKTV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD LNPEYLEHDAYAVFSQLMETAEPWFSTFEHDGQKGKETLMTPIPFARPQDLGPTIAIVTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LNPEYLEHDAYAVFSQLMETAEPWFSTFEHDGQKGKETLMTPIPFARPQDLGPTIAIVTK
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD VNQIQDHLLKKHDIELYMHLNRLEIAPQIYGLRWVRLLFGREFPLQDLLVVWDALFADGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VNQIQDHLLKKHDIELYMHLNRLEIAPQIYGLRWVRLLFGREFPLQDLLVVWDALFADGL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD SLGLVDYIFVAMLLYIRDALISSNYQTCLGLLMHYPFIGDVHSLILKALFLRDPKRNPRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SLGLVDYIFVAMLLYIRDALISSNYQTCLGLLMHYPFIGDVHSLILKALFLRDPKRNPRP
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD VTYQFHPNLDYYKARGADLMNKSRTNAKGAPLNINKVSNSLINFGRKLISPAMAPGSAGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VTYQFHPNLDYYKARGADLMNKSRTNAKGAPLNINKVSNSLINFGRKLISPAMAPGSAGG
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD PVPGGNSSSSSSVVIPTRTSAEAPSHHLQQQQQQQRLMKSESMPVQLNKGLSSKNISSSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PVPGGNSSSSSSVVIPTRTSAEAPSHHLQQQQQQQRLMKSESMPVQLNKGLSSKNISSSP
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD SVESLPGGREFTGSPPSSATKKDSFFSNISRSRSHSKTMGRKESEEELEAQISFLQGQLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SVESLPGGREFTGSPPSSATKKDSFFSNISRSRSHSKTMGRKESEEELEAQISFLQGQLN
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD DLDAMCKYCAKVMDTHLVNIQDVILQENLEKEDQILVSLAGLKQIKDILKGSLRFNQSQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DLDAMCKYCAKVMDTHLVNIQDVILQENLEKEDQILVSLAGLKQIKDILKGSLRFNQSQL
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD EAEENEQITIADNHYCSSGQGQGRGQGQSVQMSGAIKQASSETPGCTDRGNSDDFILISK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EAEENEQITIADNHYCSSGQGQGRGQGQSVQMSGAIKQASSETPGCTDRGNSDDFILISK
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD DDDGSSARGSFSGQAQPLRTLRSTSGKSQAPVCSPLVFSDPLMGPASASSSNPSSSPDDD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DDDGSSARGSFSGQAQPLRTLRSTSGKSQAPVCSPLVFSDPLMGPASASSSNPSSSPDDD
              730       740       750       760       770       780

              790     
pF1KSD SSKDSGFTIVSPLDI
       :::::::::::::::
NP_055 SSKDSGFTIVSPLDI
              790     

>>XP_016863046 (OMIM: 615740) PREDICTED: TBC1 domain fam  (795 aa)
 initn: 5283 init1: 5283 opt: 5283  Z-score: 4274.6  bits: 801.8 E(85289):    0
Smith-Waterman score: 5283; 100.0% identity (100.0% similar) in 795 aa overlap (1-795:1-795)

               10        20        30        40        50        60
pF1KSD MYHSLSETRHPLQPEEQEVGIDPLSSYSNKSGGDSNKNGRRTSSTLDSEGTFNSYRKEWE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MYHSLSETRHPLQPEEQEVGIDPLSSYSNKSGGDSNKNGRRTSSTLDSEGTFNSYRKEWE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD ELFVNNNYLATIRQKGINGQLRSSRFRSICWKLFLCVLPQDKSQWISRIEELRAWYSNIK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELFVNNNYLATIRQKGINGQLRSSRFRSICWKLFLCVLPQDKSQWISRIEELRAWYSNIK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD EIHITNPRKVVGQQDLMINNPLSQDEGSLWNKFFQDKELRSMIEQDVKRTFPEMQFFQQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EIHITNPRKVVGQQDLMINNPLSQDEGSLWNKFFQDKELRSMIEQDVKRTFPEMQFFQQE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD NVRKILTDVLFCYARENEQLLYKQGMHELLAPIVFVLHCDHQAFLHASESAQPSEEMKTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NVRKILTDVLFCYARENEQLLYKQGMHELLAPIVFVLHCDHQAFLHASESAQPSEEMKTV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD LNPEYLEHDAYAVFSQLMETAEPWFSTFEHDGQKGKETLMTPIPFARPQDLGPTIAIVTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNPEYLEHDAYAVFSQLMETAEPWFSTFEHDGQKGKETLMTPIPFARPQDLGPTIAIVTK
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD VNQIQDHLLKKHDIELYMHLNRLEIAPQIYGLRWVRLLFGREFPLQDLLVVWDALFADGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNQIQDHLLKKHDIELYMHLNRLEIAPQIYGLRWVRLLFGREFPLQDLLVVWDALFADGL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD SLGLVDYIFVAMLLYIRDALISSNYQTCLGLLMHYPFIGDVHSLILKALFLRDPKRNPRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLGLVDYIFVAMLLYIRDALISSNYQTCLGLLMHYPFIGDVHSLILKALFLRDPKRNPRP
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD VTYQFHPNLDYYKARGADLMNKSRTNAKGAPLNINKVSNSLINFGRKLISPAMAPGSAGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTYQFHPNLDYYKARGADLMNKSRTNAKGAPLNINKVSNSLINFGRKLISPAMAPGSAGG
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD PVPGGNSSSSSSVVIPTRTSAEAPSHHLQQQQQQQRLMKSESMPVQLNKGLSSKNISSSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVPGGNSSSSSSVVIPTRTSAEAPSHHLQQQQQQQRLMKSESMPVQLNKGLSSKNISSSP
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD SVESLPGGREFTGSPPSSATKKDSFFSNISRSRSHSKTMGRKESEEELEAQISFLQGQLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVESLPGGREFTGSPPSSATKKDSFFSNISRSRSHSKTMGRKESEEELEAQISFLQGQLN
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD DLDAMCKYCAKVMDTHLVNIQDVILQENLEKEDQILVSLAGLKQIKDILKGSLRFNQSQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLDAMCKYCAKVMDTHLVNIQDVILQENLEKEDQILVSLAGLKQIKDILKGSLRFNQSQL
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD EAEENEQITIADNHYCSSGQGQGRGQGQSVQMSGAIKQASSETPGCTDRGNSDDFILISK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAEENEQITIADNHYCSSGQGQGRGQGQSVQMSGAIKQASSETPGCTDRGNSDDFILISK
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD DDDGSSARGSFSGQAQPLRTLRSTSGKSQAPVCSPLVFSDPLMGPASASSSNPSSSPDDD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDDGSSARGSFSGQAQPLRTLRSTSGKSQAPVCSPLVFSDPLMGPASASSSNPSSSPDDD
              730       740       750       760       770       780

              790     
pF1KSD SSKDSGFTIVSPLDI
       :::::::::::::::
XP_016 SSKDSGFTIVSPLDI
              790     

>>XP_016863047 (OMIM: 615740) PREDICTED: TBC1 domain fam  (795 aa)
 initn: 5283 init1: 5283 opt: 5283  Z-score: 4274.6  bits: 801.8 E(85289):    0
Smith-Waterman score: 5283; 100.0% identity (100.0% similar) in 795 aa overlap (1-795:1-795)

               10        20        30        40        50        60
pF1KSD MYHSLSETRHPLQPEEQEVGIDPLSSYSNKSGGDSNKNGRRTSSTLDSEGTFNSYRKEWE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MYHSLSETRHPLQPEEQEVGIDPLSSYSNKSGGDSNKNGRRTSSTLDSEGTFNSYRKEWE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD ELFVNNNYLATIRQKGINGQLRSSRFRSICWKLFLCVLPQDKSQWISRIEELRAWYSNIK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELFVNNNYLATIRQKGINGQLRSSRFRSICWKLFLCVLPQDKSQWISRIEELRAWYSNIK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD EIHITNPRKVVGQQDLMINNPLSQDEGSLWNKFFQDKELRSMIEQDVKRTFPEMQFFQQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EIHITNPRKVVGQQDLMINNPLSQDEGSLWNKFFQDKELRSMIEQDVKRTFPEMQFFQQE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD NVRKILTDVLFCYARENEQLLYKQGMHELLAPIVFVLHCDHQAFLHASESAQPSEEMKTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NVRKILTDVLFCYARENEQLLYKQGMHELLAPIVFVLHCDHQAFLHASESAQPSEEMKTV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD LNPEYLEHDAYAVFSQLMETAEPWFSTFEHDGQKGKETLMTPIPFARPQDLGPTIAIVTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNPEYLEHDAYAVFSQLMETAEPWFSTFEHDGQKGKETLMTPIPFARPQDLGPTIAIVTK
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD VNQIQDHLLKKHDIELYMHLNRLEIAPQIYGLRWVRLLFGREFPLQDLLVVWDALFADGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNQIQDHLLKKHDIELYMHLNRLEIAPQIYGLRWVRLLFGREFPLQDLLVVWDALFADGL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD SLGLVDYIFVAMLLYIRDALISSNYQTCLGLLMHYPFIGDVHSLILKALFLRDPKRNPRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLGLVDYIFVAMLLYIRDALISSNYQTCLGLLMHYPFIGDVHSLILKALFLRDPKRNPRP
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD VTYQFHPNLDYYKARGADLMNKSRTNAKGAPLNINKVSNSLINFGRKLISPAMAPGSAGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTYQFHPNLDYYKARGADLMNKSRTNAKGAPLNINKVSNSLINFGRKLISPAMAPGSAGG
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD PVPGGNSSSSSSVVIPTRTSAEAPSHHLQQQQQQQRLMKSESMPVQLNKGLSSKNISSSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVPGGNSSSSSSVVIPTRTSAEAPSHHLQQQQQQQRLMKSESMPVQLNKGLSSKNISSSP
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD SVESLPGGREFTGSPPSSATKKDSFFSNISRSRSHSKTMGRKESEEELEAQISFLQGQLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVESLPGGREFTGSPPSSATKKDSFFSNISRSRSHSKTMGRKESEEELEAQISFLQGQLN
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD DLDAMCKYCAKVMDTHLVNIQDVILQENLEKEDQILVSLAGLKQIKDILKGSLRFNQSQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLDAMCKYCAKVMDTHLVNIQDVILQENLEKEDQILVSLAGLKQIKDILKGSLRFNQSQL
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD EAEENEQITIADNHYCSSGQGQGRGQGQSVQMSGAIKQASSETPGCTDRGNSDDFILISK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAEENEQITIADNHYCSSGQGQGRGQGQSVQMSGAIKQASSETPGCTDRGNSDDFILISK
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD DDDGSSARGSFSGQAQPLRTLRSTSGKSQAPVCSPLVFSDPLMGPASASSSNPSSSPDDD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDDGSSARGSFSGQAQPLRTLRSTSGKSQAPVCSPLVFSDPLMGPASASSSNPSSSPDDD
              730       740       750       760       770       780

              790     
pF1KSD SSKDSGFTIVSPLDI
       :::::::::::::::
XP_016 SSKDSGFTIVSPLDI
              790     

>>XP_016863053 (OMIM: 615740) PREDICTED: TBC1 domain fam  (659 aa)
 initn: 4362 init1: 4362 opt: 4362  Z-score: 3532.0  bits: 664.1 E(85289): 5.4e-190
Smith-Waterman score: 4362; 100.0% identity (100.0% similar) in 659 aa overlap (137-795:1-659)

        110       120       130       140       150       160      
pF1KSD SRIEELRAWYSNIKEIHITNPRKVVGQQDLMINNPLSQDEGSLWNKFFQDKELRSMIEQD
                                     ::::::::::::::::::::::::::::::
XP_016                               MINNPLSQDEGSLWNKFFQDKELRSMIEQD
                                             10        20        30

        170       180       190       200       210       220      
pF1KSD VKRTFPEMQFFQQENVRKILTDVLFCYARENEQLLYKQGMHELLAPIVFVLHCDHQAFLH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKRTFPEMQFFQQENVRKILTDVLFCYARENEQLLYKQGMHELLAPIVFVLHCDHQAFLH
               40        50        60        70        80        90

        230       240       250       260       270       280      
pF1KSD ASESAQPSEEMKTVLNPEYLEHDAYAVFSQLMETAEPWFSTFEHDGQKGKETLMTPIPFA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASESAQPSEEMKTVLNPEYLEHDAYAVFSQLMETAEPWFSTFEHDGQKGKETLMTPIPFA
              100       110       120       130       140       150

        290       300       310       320       330       340      
pF1KSD RPQDLGPTIAIVTKVNQIQDHLLKKHDIELYMHLNRLEIAPQIYGLRWVRLLFGREFPLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RPQDLGPTIAIVTKVNQIQDHLLKKHDIELYMHLNRLEIAPQIYGLRWVRLLFGREFPLQ
              160       170       180       190       200       210

        350       360       370       380       390       400      
pF1KSD DLLVVWDALFADGLSLGLVDYIFVAMLLYIRDALISSNYQTCLGLLMHYPFIGDVHSLIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLLVVWDALFADGLSLGLVDYIFVAMLLYIRDALISSNYQTCLGLLMHYPFIGDVHSLIL
              220       230       240       250       260       270

        410       420       430       440       450       460      
pF1KSD KALFLRDPKRNPRPVTYQFHPNLDYYKARGADLMNKSRTNAKGAPLNINKVSNSLINFGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KALFLRDPKRNPRPVTYQFHPNLDYYKARGADLMNKSRTNAKGAPLNINKVSNSLINFGR
              280       290       300       310       320       330

        470       480       490       500       510       520      
pF1KSD KLISPAMAPGSAGGPVPGGNSSSSSSVVIPTRTSAEAPSHHLQQQQQQQRLMKSESMPVQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLISPAMAPGSAGGPVPGGNSSSSSSVVIPTRTSAEAPSHHLQQQQQQQRLMKSESMPVQ
              340       350       360       370       380       390

        530       540       550       560       570       580      
pF1KSD LNKGLSSKNISSSPSVESLPGGREFTGSPPSSATKKDSFFSNISRSRSHSKTMGRKESEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNKGLSSKNISSSPSVESLPGGREFTGSPPSSATKKDSFFSNISRSRSHSKTMGRKESEE
              400       410       420       430       440       450

        590       600       610       620       630       640      
pF1KSD ELEAQISFLQGQLNDLDAMCKYCAKVMDTHLVNIQDVILQENLEKEDQILVSLAGLKQIK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELEAQISFLQGQLNDLDAMCKYCAKVMDTHLVNIQDVILQENLEKEDQILVSLAGLKQIK
              460       470       480       490       500       510

        650       660       670       680       690       700      
pF1KSD DILKGSLRFNQSQLEAEENEQITIADNHYCSSGQGQGRGQGQSVQMSGAIKQASSETPGC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DILKGSLRFNQSQLEAEENEQITIADNHYCSSGQGQGRGQGQSVQMSGAIKQASSETPGC
              520       530       540       550       560       570

        710       720       730       740       750       760      
pF1KSD TDRGNSDDFILISKDDDGSSARGSFSGQAQPLRTLRSTSGKSQAPVCSPLVFSDPLMGPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TDRGNSDDFILISKDDDGSSARGSFSGQAQPLRTLRSTSGKSQAPVCSPLVFSDPLMGPA
              580       590       600       610       620       630

        770       780       790     
pF1KSD SASSSNPSSSPDDDSSKDSGFTIVSPLDI
       :::::::::::::::::::::::::::::
XP_016 SASSSNPSSSPDDDSSKDSGFTIVSPLDI
              640       650         

>>XP_016863054 (OMIM: 615740) PREDICTED: TBC1 domain fam  (659 aa)
 initn: 4362 init1: 4362 opt: 4362  Z-score: 3532.0  bits: 664.1 E(85289): 5.4e-190
Smith-Waterman score: 4362; 100.0% identity (100.0% similar) in 659 aa overlap (137-795:1-659)

        110       120       130       140       150       160      
pF1KSD SRIEELRAWYSNIKEIHITNPRKVVGQQDLMINNPLSQDEGSLWNKFFQDKELRSMIEQD
                                     ::::::::::::::::::::::::::::::
XP_016                               MINNPLSQDEGSLWNKFFQDKELRSMIEQD
                                             10        20        30

        170       180       190       200       210       220      
pF1KSD VKRTFPEMQFFQQENVRKILTDVLFCYARENEQLLYKQGMHELLAPIVFVLHCDHQAFLH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKRTFPEMQFFQQENVRKILTDVLFCYARENEQLLYKQGMHELLAPIVFVLHCDHQAFLH
               40        50        60        70        80        90

        230       240       250       260       270       280      
pF1KSD ASESAQPSEEMKTVLNPEYLEHDAYAVFSQLMETAEPWFSTFEHDGQKGKETLMTPIPFA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASESAQPSEEMKTVLNPEYLEHDAYAVFSQLMETAEPWFSTFEHDGQKGKETLMTPIPFA
              100       110       120       130       140       150

        290       300       310       320       330       340      
pF1KSD RPQDLGPTIAIVTKVNQIQDHLLKKHDIELYMHLNRLEIAPQIYGLRWVRLLFGREFPLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RPQDLGPTIAIVTKVNQIQDHLLKKHDIELYMHLNRLEIAPQIYGLRWVRLLFGREFPLQ
              160       170       180       190       200       210

        350       360       370       380       390       400      
pF1KSD DLLVVWDALFADGLSLGLVDYIFVAMLLYIRDALISSNYQTCLGLLMHYPFIGDVHSLIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLLVVWDALFADGLSLGLVDYIFVAMLLYIRDALISSNYQTCLGLLMHYPFIGDVHSLIL
              220       230       240       250       260       270

        410       420       430       440       450       460      
pF1KSD KALFLRDPKRNPRPVTYQFHPNLDYYKARGADLMNKSRTNAKGAPLNINKVSNSLINFGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KALFLRDPKRNPRPVTYQFHPNLDYYKARGADLMNKSRTNAKGAPLNINKVSNSLINFGR
              280       290       300       310       320       330

        470       480       490       500       510       520      
pF1KSD KLISPAMAPGSAGGPVPGGNSSSSSSVVIPTRTSAEAPSHHLQQQQQQQRLMKSESMPVQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLISPAMAPGSAGGPVPGGNSSSSSSVVIPTRTSAEAPSHHLQQQQQQQRLMKSESMPVQ
              340       350       360       370       380       390

        530       540       550       560       570       580      
pF1KSD LNKGLSSKNISSSPSVESLPGGREFTGSPPSSATKKDSFFSNISRSRSHSKTMGRKESEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNKGLSSKNISSSPSVESLPGGREFTGSPPSSATKKDSFFSNISRSRSHSKTMGRKESEE
              400       410       420       430       440       450

        590       600       610       620       630       640      
pF1KSD ELEAQISFLQGQLNDLDAMCKYCAKVMDTHLVNIQDVILQENLEKEDQILVSLAGLKQIK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELEAQISFLQGQLNDLDAMCKYCAKVMDTHLVNIQDVILQENLEKEDQILVSLAGLKQIK
              460       470       480       490       500       510

        650       660       670       680       690       700      
pF1KSD DILKGSLRFNQSQLEAEENEQITIADNHYCSSGQGQGRGQGQSVQMSGAIKQASSETPGC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DILKGSLRFNQSQLEAEENEQITIADNHYCSSGQGQGRGQGQSVQMSGAIKQASSETPGC
              520       530       540       550       560       570

        710       720       730       740       750       760      
pF1KSD TDRGNSDDFILISKDDDGSSARGSFSGQAQPLRTLRSTSGKSQAPVCSPLVFSDPLMGPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TDRGNSDDFILISKDDDGSSARGSFSGQAQPLRTLRSTSGKSQAPVCSPLVFSDPLMGPA
              580       590       600       610       620       630

        770       780       790     
pF1KSD SASSSNPSSSPDDDSSKDSGFTIVSPLDI
       :::::::::::::::::::::::::::::
XP_016 SASSSNPSSSPDDDSSKDSGFTIVSPLDI
              640       650         

>>XP_016863052 (OMIM: 615740) PREDICTED: TBC1 domain fam  (659 aa)
 initn: 4362 init1: 4362 opt: 4362  Z-score: 3532.0  bits: 664.1 E(85289): 5.4e-190
Smith-Waterman score: 4362; 100.0% identity (100.0% similar) in 659 aa overlap (137-795:1-659)

        110       120       130       140       150       160      
pF1KSD SRIEELRAWYSNIKEIHITNPRKVVGQQDLMINNPLSQDEGSLWNKFFQDKELRSMIEQD
                                     ::::::::::::::::::::::::::::::
XP_016                               MINNPLSQDEGSLWNKFFQDKELRSMIEQD
                                             10        20        30

        170       180       190       200       210       220      
pF1KSD VKRTFPEMQFFQQENVRKILTDVLFCYARENEQLLYKQGMHELLAPIVFVLHCDHQAFLH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKRTFPEMQFFQQENVRKILTDVLFCYARENEQLLYKQGMHELLAPIVFVLHCDHQAFLH
               40        50        60        70        80        90

        230       240       250       260       270       280      
pF1KSD ASESAQPSEEMKTVLNPEYLEHDAYAVFSQLMETAEPWFSTFEHDGQKGKETLMTPIPFA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASESAQPSEEMKTVLNPEYLEHDAYAVFSQLMETAEPWFSTFEHDGQKGKETLMTPIPFA
              100       110       120       130       140       150

        290       300       310       320       330       340      
pF1KSD RPQDLGPTIAIVTKVNQIQDHLLKKHDIELYMHLNRLEIAPQIYGLRWVRLLFGREFPLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RPQDLGPTIAIVTKVNQIQDHLLKKHDIELYMHLNRLEIAPQIYGLRWVRLLFGREFPLQ
              160       170       180       190       200       210

        350       360       370       380       390       400      
pF1KSD DLLVVWDALFADGLSLGLVDYIFVAMLLYIRDALISSNYQTCLGLLMHYPFIGDVHSLIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLLVVWDALFADGLSLGLVDYIFVAMLLYIRDALISSNYQTCLGLLMHYPFIGDVHSLIL
              220       230       240       250       260       270

        410       420       430       440       450       460      
pF1KSD KALFLRDPKRNPRPVTYQFHPNLDYYKARGADLMNKSRTNAKGAPLNINKVSNSLINFGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KALFLRDPKRNPRPVTYQFHPNLDYYKARGADLMNKSRTNAKGAPLNINKVSNSLINFGR
              280       290       300       310       320       330

        470       480       490       500       510       520      
pF1KSD KLISPAMAPGSAGGPVPGGNSSSSSSVVIPTRTSAEAPSHHLQQQQQQQRLMKSESMPVQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLISPAMAPGSAGGPVPGGNSSSSSSVVIPTRTSAEAPSHHLQQQQQQQRLMKSESMPVQ
              340       350       360       370       380       390

        530       540       550       560       570       580      
pF1KSD LNKGLSSKNISSSPSVESLPGGREFTGSPPSSATKKDSFFSNISRSRSHSKTMGRKESEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNKGLSSKNISSSPSVESLPGGREFTGSPPSSATKKDSFFSNISRSRSHSKTMGRKESEE
              400       410       420       430       440       450

        590       600       610       620       630       640      
pF1KSD ELEAQISFLQGQLNDLDAMCKYCAKVMDTHLVNIQDVILQENLEKEDQILVSLAGLKQIK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELEAQISFLQGQLNDLDAMCKYCAKVMDTHLVNIQDVILQENLEKEDQILVSLAGLKQIK
              460       470       480       490       500       510

        650       660       670       680       690       700      
pF1KSD DILKGSLRFNQSQLEAEENEQITIADNHYCSSGQGQGRGQGQSVQMSGAIKQASSETPGC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DILKGSLRFNQSQLEAEENEQITIADNHYCSSGQGQGRGQGQSVQMSGAIKQASSETPGC
              520       530       540       550       560       570

        710       720       730       740       750       760      
pF1KSD TDRGNSDDFILISKDDDGSSARGSFSGQAQPLRTLRSTSGKSQAPVCSPLVFSDPLMGPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TDRGNSDDFILISKDDDGSSARGSFSGQAQPLRTLRSTSGKSQAPVCSPLVFSDPLMGPA
              580       590       600       610       620       630

        770       780       790     
pF1KSD SASSSNPSSSPDDDSSKDSGFTIVSPLDI
       :::::::::::::::::::::::::::::
XP_016 SASSSNPSSSPDDDSSKDSGFTIVSPLDI
              640       650         




795 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 00:40:59 2016 done: Thu Nov  3 00:41:00 2016
 Total Scan time: 10.280 Total Display time:  0.210

Function used was FASTA [36.3.4 Apr, 2011]
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