Result of FASTA (omim) for pF1KSDA0200
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KSDA0200, 1016 aa
  1>>>pF1KSDA0200 1016 - 1016 aa - 1016 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 13.5985+/-0.000445; mu= -16.2437+/- 0.027
 mean_var=475.0683+/-99.369, 0's: 0 Z-trim(123.2): 49  B-trim: 1471 in 1/61
 Lambda= 0.058843
 statistics sampled from 42561 (42654) to 42561 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.781), E-opt: 0.2 (0.5), width:  16
 Scan time: 13.880

The best scores are:                                      opt bits E(85289)
NP_055572 (OMIM: 605424) mastermind-like protein 1 (1016) 6904 601.3 8.6e-171
NP_061187 (OMIM: 608991) mastermind-like protein 3 (1133)  959 96.6   8e-19
NP_115803 (OMIM: 607537) mastermind-like protein 2 (1156)  526 59.9 9.4e-08
XP_011541327 (OMIM: 607537) PREDICTED: mastermind- ( 735)  427 51.4 2.2e-05


>>NP_055572 (OMIM: 605424) mastermind-like protein 1 [Ho  (1016 aa)
 initn: 6904 init1: 6904 opt: 6904  Z-score: 3187.2  bits: 601.3 E(85289): 8.6e-171
Smith-Waterman score: 6904; 100.0% identity (100.0% similar) in 1016 aa overlap (1-1016:1-1016)

               10        20        30        40        50        60
pF1KSD MVLPTCPMAEFALPRHSAVMERLRRRIELCRRHHSTCEARYEAVSPERLELERQHTFALH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MVLPTCPMAEFALPRHSAVMERLRRRIELCRRHHSTCEARYEAVSPERLELERQHTFALH
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD QRCIQAKAKRAGKHRQPPAATAPAPAAPAPRLDAADGPEHGRPATHLHDTVKRNLDSATS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QRCIQAKAKRAGKHRQPPAATAPAPAAPAPRLDAADGPEHGRPATHLHDTVKRNLDSATS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD PQNGDQQNGYGDLFPGHKKTRREAPLGVAISSNGLPPASPLGQSDKPSGADALQSSGKHS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PQNGDQQNGYGDLFPGHKKTRREAPLGVAISSNGLPPASPLGQSDKPSGADALQSSGKHS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD LGLDSLNKKRLADSSLHLNGGSNPSESFPLSLNKELKQEPVEDLPCMITGTVGSISQSNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LGLDSLNKKRLADSSLHLNGGSNPSESFPLSLNKELKQEPVEDLPCMITGTVGSISQSNL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD MPDLNLNEQEWKELIEELNRSVPDEDMKDLFNEDFEEKKDPESSGSATQTPLAQDINIKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MPDLNLNEQEWKELIEELNRSVPDEDMKDLFNEDFEEKKDPESSGSATQTPLAQDINIKT
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD EFSPAAFEQEQLGSPQVRAGSAGQTFLGPSSAPVSTDSPSLGGSQTLFHTSGQPRADNPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EFSPAAFEQEQLGSPQVRAGSAGQTFLGPSSAPVSTDSPSLGGSQTLFHTSGQPRADNPS
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD PNLMPASAQAQNAQRALAGVVLPSQGPGGASELSSAHQLQQIAAKQKREQMLQNPQQATP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PNLMPASAQAQNAQRALAGVVLPSQGPGGASELSSAHQLQQIAAKQKREQMLQNPQQATP
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD APAPGQMSTWQQTGPSHSSLDVPYPMEKPASPSSYKQDFTNSKLLMMPSVNKSSPRPGGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 APAPGQMSTWQQTGPSHSSLDVPYPMEKPASPSSYKQDFTNSKLLMMPSVNKSSPRPGGP
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD YLQPSHVNLLSHQPPSNLNQNSANNQGSVLDYGNTKPLSHYKADCGQGSPGSGQSKPALM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 YLQPSHVNLLSHQPPSNLNQNSANNQGSVLDYGNTKPLSHYKADCGQGSPGSGQSKPALM
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD AYLPQQLSHISHEQNSLFLMKPKPGNMPFRSLVPPGQEQNPSSVPVQAQATSVGTQPPAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 AYLPQQLSHISHEQNSLFLMKPKPGNMPFRSLVPPGQEQNPSSVPVQAQATSVGTQPPAV
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD SVASSHNSSPYLSSQQQAAVMKQHQLLLDQQKQREQQQKHLQQQQFLQRQQHLLAEQEKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SVASSHNSSPYLSSQQQAAVMKQHQLLLDQQKQREQQQKHLQQQQFLQRQQHLLAEQEKQ
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD QFQRHLTRPPPQYQDPTQGSFPQQVGQFTGSSAAVPGMNTLGPSNSSCPRVFPQAGNLMP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QFQRHLTRPPPQYQDPTQGSFPQQVGQFTGSSAAVPGMNTLGPSNSSCPRVFPQAGNLMP
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD MGPGHASVSSLPTNSGQQDRGVAQFPGSQNMPQSSLYGMASGITQIVAQPPPQATNGHAH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MGPGHASVSSLPTNSGQQDRGVAQFPGSQNMPQSSLYGMASGITQIVAQPPPQATNGHAH
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KSD IPRQTNVGQNTSVSAAYGQNSLGSSGLSQQHNKGTLNPGLTKPPVPRVSPAMGGQNSSWQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 IPRQTNVGQNTSVSAAYGQNSLGSSGLSQQHNKGTLNPGLTKPPVPRVSPAMGGQNSSWQ
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KSD HQGMPNLSGQTPGNSNVSPFTAASSFHMQQQAHLKMSSPQFSQAVPNRPMAPMSSAAAVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 HQGMPNLSGQTPGNSNVSPFTAASSFHMQQQAHLKMSSPQFSQAVPNRPMAPMSSAAAVG
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KSD SLLPPVSAQQRTSAPAPAPPPTAPQQGLPGLSPAGPELGAFSQSPASQMGGRAGLHCTQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SLLPPVSAQQRTSAPAPAPPPTAPQQGLPGLSPAGPELGAFSQSPASQMGGRAGLHCTQA
              910       920       930       940       950       960

              970       980       990      1000      1010      
pF1KSD YPVRTAGQELPFAYSGQPGGSGLSSVAGHTDLIDSLLKNRTSEEWMSDLDDLLGSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 YPVRTAGQELPFAYSGQPGGSGLSSVAGHTDLIDSLLKNRTSEEWMSDLDDLLGSQ
              970       980       990      1000      1010      

>>NP_061187 (OMIM: 608991) mastermind-like protein 3 [Ho  (1133 aa)
 initn: 1055 init1: 366 opt: 959  Z-score: 459.0  bits: 96.6 E(85289): 8e-19
Smith-Waterman score: 1802; 35.9% identity (63.7% similar) in 1070 aa overlap (12-981:66-1099)

                                  10        20        30        40 
pF1KSD                    MVLPTCPMAEFALPRHSAVMERLRRRIELCRRHHSTCEARY
                                     :.:.::.:.::::.::: ::::: .:: ::
NP_061 TPNSTPAAPSSNHPAAGGCGGSGGPGGGSAAVPKHSTVVERLRQRIEGCRRHHVNCENRY
          40        50        60        70        80        90     

              50        60        70        80        90       100 
pF1KSD EAVSPERLELERQHTFALHQRCIQAKAKRAGKHRQPPAATAPAPAAPAPRLDAADGPEHG
       . .. :.:::::. : .:.:: .. .::..:      ..    :. :    .::.. ...
NP_061 QQAQVEQLELERRDTVSLYQRTLEQRAKKSGAG----TGKQQHPSKPQQDAEAASAEQRN
         100       110       120           130       140       150 

             110       120       130         140        150        
pF1KSD RPATHLHDTVKRNLDSATSPQNGDQQNGY--GDLFPGHKKTRREAPLGV-AI----SSNG
       .    :..::::.:..: :: :::::::   :.. :  :. :..   :. ::    :.  
NP_061 HTLIMLQETVKRKLEGARSPLNGDQQNGACDGNFSPTSKRIRKDISAGMEAINNLPSNMP
             160       170       180       190       200       210 

          160        170       180         190       200       210 
pF1KSD LPPASPLGQSD-KPSGADALQSSGKHSLGL-DSLNKK-RLADSSLHLNGGSNPSESFPLS
       :: :::: : : :::    ::.:: :. :: ..:.:. :: . .: .:: :.  .:: . 
NP_061 LPSASPLHQLDLKPSL--PLQNSGTHTPGLLEDLSKNGRLPEIKLPVNGCSDLEDSFTIL
             220         230       240       250       260         

             220       230       240       250       260       270 
pF1KSD LNKELKQEPVEDLPCMITGTVGSISQSNLMPDLNLNEQEWKELIEELNRSVPDEDMKDLF
        .:.:::::..:  :. :. ..  .:..:. :.:::.:::.:::.::  .::..:..:::
NP_061 QSKDLKQEPLDDPTCIDTSETSLSNQNKLFSDINLNDQEWQELIDELANTVPEDDIQDLF
     270       280       290       300       310       320         

             280       290        300       310       320       330
pF1KSD NEDFEEKKDPESSGSATQTPLAQD-INIKTEFSPAAFEQEQLGSPQVRAGSAGQTFLGPS
       ::::::::.:: :  ::.:::.:.  ..:.. : . : . ..::::.: .:.:  :   :
NP_061 NEDFEEKKEPEFSQPATETPLSQESASVKSDPSHSPFAHVSMGSPQARPSSSGPPF---S
     330       340       350       360       370       380         

              340       350           360       370       380      
pF1KSD SAPVSTDSPSLGGSQTLFHTSGQPR---ADNP-SPNLMPASAQAQNAQRALAGVVL-PS-
       .. ..:. ::.... .  . ...:    ...: .::   : . .:   :   : .: :. 
NP_061 TVSTATSLPSVASTPAAPNPASSPANCAVQSPQTPN--QAHTPGQAPPRPGNGYLLNPAA
        390       400       410       420         430       440    

                   390       400                      410       420
pF1KSD -------QGPGG--ASELSSAHQLQQIAAKQKR---------------EQMLQNPQQATP
              .:: .  .:..: :.::.:.::.:..               .:. :. ::   
NP_061 VTVAGSASGPVAVPSSDMSPAEQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQ
          450       460       470       480       490       500    

              430       440       450       460       470       480
pF1KSD APAPGQMSTWQQTGPSHSSLDVPYPMEKPASPSSYKQDFTNSKLLMMPSVNKSSPRPGGP
           .: :.:.  ::  :   . .  ::: ::  : : :.:.. .. : .:. .    . 
NP_061 QQHSNQTSNWSPLGPPSSPYGAAFTAEKPNSPMMYPQAFNNQNPIVPPMANNLQKTTMNN
          510       520       530       540       550       560    

              490       500       510       520         530        
pF1KSD YLQPSHVNLLSHQPPSNLNQNSANNQGSVLDYGNTKPLSHYKADCGQ--GSPGSGQSKPA
       ::  .:.:....:: .::. :: :.: ..: :::::::.:..:: .:    : .. .:  
NP_061 YLPQNHMNMINQQP-NNLGTNSLNKQHNILTYGNTKPLTHFNADLSQRMTPPVANPNKNP
          570        580       590       600       610       620   

      540                               550       560          570 
pF1KSD LMAYLPQQL------------------------SHISHEQNSLFLMKPKP-GNMP--FRS
       :: :. ::                         .:.:..:. :.::: :   :.:  . .
NP_061 LMPYIQQQQQQQQQQQQQQQQQQPPPPQLQAPRAHLSEDQKRLLLMKQKGVMNQPMAYAA
           630       640       650       660       670       680   

             580       590       600         610        620        
pF1KSD LVPPGQEQNPSSVPVQAQATSVGTQPPAVS--VASSHNSSP-YLSSQQQAAVMKQHQLLL
       :   ::::.: ..: .. .   .. ::. .  :...  ..: .:.:: :::.::  :.:.
NP_061 LPSHGQEQHPVGLP-RTTGPMQSSVPPGSGGMVSGASPAGPGFLGSQPQAAIMK--QMLI
           690        700       710       720       730         740

      630       640          650       660       670       680     
pF1KSD DQQKQREQQQKHL---QQQQFLQRQQHLLAEQEKQQFQRHLTRPPPQYQDPTQGSFP-QQ
       ::. :  .:::.    .:.:  :.::..::::. :  : ::   : :. .: .. .: ::
NP_061 DQRAQLIEQQKQQFLREQRQQQQQQQQILAEQQLQ--QSHL---PRQHLQPQRNPYPVQQ
              750       760       770            780       790     

          690          700       710       720       730       740 
pF1KSD VGQFTGSS---AAVPGMNTLGPSNSSCPRVFPQAGNLMPMGPGHASVSSLPTNSGQQDRG
       :.:: ::    ::: .. .:    .:  :.. : ...: .::.. . ... : ..:.. :
NP_061 VNQFQGSPQDIAAVRSQAALQSMRTS--RLMAQNAGMMGIGPSQ-NPGTMATAAAQSEMG
         800       810       820         830        840       850  

             750       760       770           780       790       
pF1KSD VAQFPGSQNMPQSSLYGMASGITQIVAQPPPQA----TNGHAHIPRQTNVGQNTSVSAAY
       .: . ..    : ..:.:..:.::.. : : :.    :...:. :::   ::.... ...
NP_061 LAPY-STTPTSQPGMYNMSTGMTQML-QHPNQSGMSITHNQAQGPRQPASGQGVGMVSGF
             860       870        880       890       900       910

       800       810         820        830          840       850 
pF1KSD GQNSLGSSGLSQQHN--KGTLNPGLTKPPVP-RVSPAMGG--QNS-SWQHQGMPNLSGQT
       ::. : .:...:::   :: .. .: .: .: :..  ::   :.. :::.... .. :.:
NP_061 GQSMLVNSAITQQHPQMKGPVGQALPRPQAPPRLQSLMGTVQQGAQSWQQRSLQGMPGRT
              920       930       940       950       960       970

             860       870         880          890       900      
pF1KSD PGNSNVSPFTAASSFHMQQ-QAHL-KMSSPQ-FSQAV--PNRPMAPMSSAAAVG-SLLPP
        :  ...::. ..:. .:  : .: :.  :: .::.:   :   .   . ::.: ...: 
NP_061 SG--ELGPFNNGASYPLQAGQPRLTKQHFPQGLSQSVVDANTGTVRTLNPAAMGRQMMPS
                980       990      1000      1010      1020        

         910       920       930       940          950       960  
pF1KSD VSAQQRTSAPAPAPPPTAPQQGLPGLSPAGPELGAFSQSPASQM---GGRAGLHCTQAYP
       . .:: ::   :          . ::: . : . :::: ::.:.   :. :    .::: 
NP_061 LPGQQGTSQARPMV--------MSGLSQGVPGMPAFSQPPAQQQIPSGSFAPSSQSQAYE
     1030      1040              1050      1060      1070      1080

            970        980       990      1000      1010      
pF1KSD VRTAGQELPFAYSGQ-PGGSGLSSVAGHTDLIDSLLKNRTSEEWMSDLDDLLGSQ
        :.: :.. . :::.  :::                                   
NP_061 -RNAPQDVSYNYSGDGAGGSFPGLPDGADLVDSIIKGGPGDEWMQELDELFGNP 
              1090      1100      1110      1120      1130    

>>NP_115803 (OMIM: 607537) mastermind-like protein 2 [Ho  (1156 aa)
 initn: 467 init1: 187 opt: 526  Z-score: 260.2  bits: 59.9 E(85289): 9.4e-08
Smith-Waterman score: 809; 27.3% identity (52.6% similar) in 1069 aa overlap (14-906:30-1044)

                               10         20        30        40   
pF1KSD                 MVLPTCPMAEFALPR-HSAVMERLRRRIELCRRHHSTCEARYEA
                                    :: :::..:::: :: .::.:: .::.::: 
NP_115 MGDTAPPQAPAGGLGGASGAGLLGGGSVTPRVHSAIVERLRARIAVCRQHHLSCEGRYER
               10        20        30        40        50        60

            50        60         70        80              90      
pF1KSD VSPERLELERQHTFALHQRCIQAK-AKRAGKHRQPPAATA------PAPAAPAPRLDAAD
          :  . ::. :. : .   ... :..:::: .  :..:      : ::::    .:: 
NP_115 GRAESSDRERESTLQLLSLVQHGQGARKAGKHTKATATAATTTAPPPPPAAPPAASQAAA
               70        80        90       100       110       120

        100       110       120                     130       140  
pF1KSD GPEHGRPATHLHDTVKRNLDSATS------------PQN--GDQQNGYGDLFPGHKKTRR
             :  . :   .. :.:...            : .  :::.:.    . :  : ..
NP_115 TAAPPPPPDYHHHHQQHLLNSSNNGGSGGINGEQQPPASTPGDQRNSALIALQGSLKRKQ
              130       140       150       160       170       180

            150         160             170        180         190 
pF1KSD EAPLGVAISS--NGLPPASPLGQS------DKPSGADALQ-SSGKHSL--GLDSLNKKRL
        . :. : :.  ::.   : :  .      .  .:  .:: ..:. ..  :   ...  :
NP_115 VVNLSPANSKRPNGFVDNSFLDIKRIRVGENLSAGQGGLQINNGQSQIMSGTLPMSQAPL
              190       200       210       220       230       240

             200        210       220       230       240          
pF1KSD ADSSLHLNGGSNPSES-FPLSLNKELKQEPVEDLPCMITGTVGSISQSNLMPDL------
         ..   .   .:... : ..: ::.:.:: : : :      :...: :..:.       
NP_115 RKTNTLPSHTHSPGNGLFNMGL-KEVKKEPGETLSCS-KHMDGQMTQENIFPNRYGDDPG
              250       260        270        280       290        

           250        260          270       280             290   
pF1KSD -NLNEQEWKELIEEL-NRSVP---DEDMKDLFNEDFEEKKDP------ESSGSATQTPL-
        .: . : .::..:: : :::   : ......:  ...  ::      ..:  .:  :  
NP_115 EQLMDPELQELFNELTNISVPPMSDLELENMINATIKQD-DPFNIDLGQQSQRSTPRPSL
      300       310       320       330        340       350       

             300       310       320       330       340       350 
pF1KSD -AQDINIKTEFSPAAFEQEQLGSPQVRAGSAGQTFLGPSSAPVSTDSPSLGGSQTLFHTS
         . : ::.:.::. . :   ::::.:  ::: .:   .:: .::.::            
NP_115 PMEKIVIKSEYSPG-LTQGPSGSPQLRPPSAGPAFSMANSA-LSTSSPI-----------
       360       370        380       390        400               

             360       370       380       390       400        410
pF1KSD GQPRADNPSPNLMPASAQAQNAQRALAGVVLPSQGPGGASELSSAHQLQQIAA-KQKREQ
              ::   .: : :::    . :. .:::      .:.: :.::.:::: .:.. .
NP_115 -------PS---VPQS-QAQPQTGSGASRALPSW-----QEVSHAQQLKQIAANRQQHAR
                    410        420            430       440        

              420       430       440       450       460       470
pF1KSD MLQNPQQATPAPAPGQMSTWQQTGPSHSSLDVPYPMEKPASPSSYKQDFTNSKLLMMPSV
       : :. ::  :.   .  :.   .::: .    :. .::  :::  .: :.  .   ::.:
NP_115 MQQHQQQHQPTNWSALPSS---AGPSPG----PFGQEKIPSPSFGQQTFS-PQSSPMPGV
      450       460          470           480       490        500

                       480       490       500       510           
pF1KSD NKSSPRP---------GGPYLQPSHVNLLSHQPPSNLNQNSANNQGSVLD--YGNTKPLS
         .: .          .::  : .:...: .: :..:...  ::   ...   :::::: 
NP_115 AGGSGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLSRSFINNPHPAMEPRQGNTKPLF
              510       520       530       540       550       560

     520        530         540       550       560       570      
pF1KSD HYKAD-CGQGSPG--SGQSKPALMAYLPQQLSHISHEQNSLFLMKPKPGNMPFR------
       :...:  .:  :.   .:.::.:. :  :: .. ...:..   .. .  ..  .      
NP_115 HFNSDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ
              570       580       590       600       610       620

                580       590                       600       610  
pF1KSD --SLVPPGQEQNPSSVPVQAQATSVGTQP----------------PAVSVASSHNSSP--
         :.    :.:. ::. .: :  .   :                 :. . :.:  :.:  
NP_115 QSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLL
              630       640       650       660       670       680

                                                                   
pF1KSD ------------------------YLSSQQQ---------------------------AA
                               :  ::::                           ..
NP_115 RSPLPLQQKLLLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQNTGPSPSPNPCSNPNTGSG
              690       700       710       720       730       740

     620       630           640       650           660       670 
pF1KSD VMKQHQLLLDQQ----KQREQQQKHLQQQQFLQRQQHLLAEQEK----QQFQRHLTRPPP
        :...: ::.::    ::  :.:   :.::.:  ::..::. ::    .:..:::.::::
NP_115 YMNSQQSLLNQQLMGKKQTLQRQIMEQKQQLLL-QQQMLADAEKIAPQDQINRHLSRPPP
              750       760       770        780       790         

               680       690       700        710       720        
pF1KSD QYQDPTQ--GSFPQQVGQFTGSSAAVPGMNTLGPSNS-SCPRVFPQAGNLMPMGPGHASV
       .:.:  .  :.. : ..:..:.:...   .. . .:  :   ..   ..:.  . :    
NP_115 DYKDQRRNVGNM-QPTAQYSGGSSTISLNSNQALANPVSTHTILTPNSSLLSTSHG----
     800       810        820       830       840       850        

      730        740       750       760       770          780    
pF1KSD SSLPT-NSGQQDRGVAQFPGSQNMPQSSLYGMASGITQIVAQPPPQ---ATNGHAHIPRQ
       . .:. ... :. :.    :.    : . :...::..:.. :  :.   :....  .:: 
NP_115 TRMPSLSTAVQNMGMY---GNLPCNQPNTYSVTSGMNQLTQQRNPKQLLANQNNPMMPRP
          860       870          880       890       900       910 

           790       800       810       820       830          840
pF1KSD TNVG-QNTSVSAAYGQNSLGSSGLSQQHNKGTLNPGLTKPPVPRVSPAMGGQNSS---WQ
        ..: .:..  :..: .:.:.:    :. . .:. .... :  :.: .:  .:..   : 
NP_115 PTLGPSNNNNVATFGAGSVGNS----QQLRPNLTHSMASMPPQRTSNVMITSNTTAPNWA
             920       930           940       950       960       

              850        860       870       880                   
pF1KSD HQGMPNLSGQTPGNSNVS-PFTAASSFHMQQQAHLKMSSPQFSQ---AVPN--------R
        :   . . ..  ...:  :  . ...  .:. .  ..: ::::   : ::        :
NP_115 SQEGTSKQQEALTSAGVRFPTGTPAAYTPNQSLQQAVGSQQFSQRAVAPPNQLTPAVQMR
       970       980       990      1000      1010      1020       

      890       900       910       920       930       940        
pF1KSD PMAPMSSAAAVGSLLPPVSAQQRTSAPAPAPPPTAPQQGLPGLSPAGPELGAFSQSPASQ
       ::  ::..   :. . :.                                          
NP_115 PMNQMSQTLN-GQTMGPLRGLNLRPNQLSTQILPNLNQSGTGLNQSRTGINQPPSLTPSN
      1030       1040      1050      1060      1070      1080      

>>XP_011541327 (OMIM: 607537) PREDICTED: mastermind-like  (735 aa)
 initn: 467 init1: 187 opt: 427  Z-score: 217.6  bits: 51.4 E(85289): 2.2e-05
Smith-Waterman score: 692; 29.9% identity (53.8% similar) in 732 aa overlap (14-674:30-688)

                               10         20        30        40   
pF1KSD                 MVLPTCPMAEFALPR-HSAVMERLRRRIELCRRHHSTCEARYEA
                                    :: :::..:::: :: .::.:: .::.::: 
XP_011 MGDTAPPQAPAGGLGGASGAGLLGGGSVTPRVHSAIVERLRARIAVCRQHHLSCEGRYER
               10        20        30        40        50        60

            50        60         70        80              90      
pF1KSD VSPERLELERQHTFALHQRCIQAK-AKRAGKHRQPPAATA------PAPAAPAPRLDAAD
          :  . ::. :. : .   ... :..:::: .  :..:      : ::::    .:: 
XP_011 GRAESSDRERESTLQLLSLVQHGQGARKAGKHTKATATAATTTAPPPPPAAPPAASQAAA
               70        80        90       100       110       120

        100       110       120                     130       140  
pF1KSD GPEHGRPATHLHDTVKRNLDSATS------------PQN--GDQQNGYGDLFPGHKKTRR
             :  . :   .. :.:...            : .  :::.:.    . :  : ..
XP_011 TAAPPPPPDYHHHHQQHLLNSSNNGGSGGINGEQQPPASTPGDQRNSALIALQGSLKRKQ
              130       140       150       160       170       180

            150         160              170        180         190
pF1KSD EAPLGVAISS--NGLPPASPL-------GQSDKPSGADALQ-SSGKHSL--GLDSLNKKR
        . :. : :.  ::.   : :       :. .  .:  .:: ..:. ..  :   ...  
XP_011 VVNLSPANSKRPNGFVDNSFLDIKRIRVGE-NLSAGQGGLQINNGQSQIMSGTLPMSQAP
              190       200       210        220       230         

              200        210       220       230       240         
pF1KSD LADSSLHLNGGSNPSES-FPLSLNKELKQEPVEDLPCMITGTVGSISQSNLMPDL-----
       :  ..   .   .:... : ..: ::.:.:: : : :      :...: :..:.      
XP_011 LRKTNTLPSHTHSPGNGLFNMGL-KEVKKEPGETLSCS-KHMDGQMTQENIFPNRYGDDP
     240       250       260        270        280       290       

            250        260          270       280             290  
pF1KSD --NLNEQEWKELIEEL-NRSVP---DEDMKDLFNEDFEEKKDP------ESSGSATQTPL
         .: . : .::..:: : :::   : ......:  ...  ::      ..:  .:  : 
XP_011 GEQLMDPELQELFNELTNISVPPMSDLELENMINATIKQD-DPFNIDLGQQSQRSTPRPS
       300       310       320       330        340       350      

              300       310       320       330       340       350
pF1KSD --AQDINIKTEFSPAAFEQEQLGSPQVRAGSAGQTFLGPSSAPVSTDSPSLGGSQTLFHT
          . : ::.:.::. . :   ::::.:  ::: .:   .:: .::.::           
XP_011 LPMEKIVIKSEYSPG-LTQGPSGSPQLRPPSAGPAFSMANSA-LSTSSPI----------
        360       370        380       390        400              

              360       370       380       390       400          
pF1KSD SGQPRADNPSPNLMPASAQAQNAQRALAGVVLPSQGPGGASELSSAHQLQQIAA-KQKRE
               ::   .: : :::    . :. .:::      .:.: :.::.:::: .:.. 
XP_011 --------PS---VPQS-QAQPQTGSGASRALPSW-----QEVSHAQQLKQIAANRQQHA
                     410        420            430       440       

     410       420       430       440       450       460         
pF1KSD QMLQNPQQATPAPAPGQMSTWQQTGPSHSSLDVPYPMEKPASPSSYKQDFTNSKLLMMPS
       .: :. ::  :.   .  :.   .::: .    :. .::  :::  .: :.  .   ::.
XP_011 RMQQHQQQHQPTNWSALPSS---AGPSPG----PFGQEKIPSPSFGQQTFS-PQSSPMPG
       450       460          470           480       490          

     470                480       490       500       510          
pF1KSD VNKSSPRP---------GGPYLQPSHVNLLSHQPPSNLNQNSANNQGSVLD--YGNTKPL
       :  .: .          .::  : .:...: .: :..:...  ::   ...   ::::::
XP_011 VAGGSGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLSRSFINNPHPAMEPRQGNTKPL
     500       510       520       530       540       550         

      520        530         540       550       560       570     
pF1KSD SHYKAD-CGQGSPG--SGQSKPALMAYLPQQLSHISHEQNSLFLMKPKPGNMPFRSLVPP
        :...:  .:  :.   .:.::.:. :  :: .. ...:..   .. .            
XP_011 FHFNSDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQ------------
     560       570       580       590       600                   

         580       590       600       610       620       630     
pF1KSD GQEQNPSSVPVQAQATSVGTQPPAVSVASSHNSSPYLSSQQQAAVMKQHQLLLDQQKQRE
        :.:. ..   : : .:...:                ..:::...  :.:    ::.:..
XP_011 -QQQQQQQQQQQQQQSSISAQQ---------------QQQQQSSISAQQQ----QQQQQQ
        610       620                      630       640           

         640       650       660         670       680       690   
pF1KSD QQQKHLQQQQFLQRQQHLLAEQEKQQF--QRHLTRPPPQYQDPTQGSFPQQVGQFTGSSA
       :::.. ::::  :.::.  . :  :..  :  :  : :  :                   
XP_011 QQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQMQNQPIAGMGYQV
       650       660       670       680       690       700       

           700       710       720       730       740       750   
pF1KSD AVPGMNTLGPSNSSCPRVFPQAGNLMPMGPGHASVSSLPTNSGQQDRGVAQFPGSQNMPQ
                                                                   
XP_011 SQQQRQQPVGVSMPDADNIESKCSCKGE                                
       710       720       730                                     




1016 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 00:37:08 2016 done: Thu Nov  3 00:37:10 2016
 Total Scan time: 13.880 Total Display time:  0.150

Function used was FASTA [36.3.4 Apr, 2011]
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