Result of FASTA (omim) for pF1KSDA0199
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KSDA0199, 1279 aa
  1>>>pF1KSDA0199 1279 - 1279 aa - 1279 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 8.4071+/-0.000369; mu= 10.4730+/- 0.023
 mean_var=218.4636+/-44.192, 0's: 0 Z-trim(120.5): 106  B-trim: 0 in 0/58
 Lambda= 0.086773
 statistics sampled from 35777 (35905) to 35777 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.726), E-opt: 0.2 (0.421), width:  16
 Scan time: 15.080

The best scores are:                                      opt bits E(85289)
NP_036367 (OMIM: 601510) sterol regulatory element (1279) 8711 1104.4       0
XP_016861407 (OMIM: 601510) PREDICTED: sterol regu (1279) 8711 1104.4       0
XP_011531803 (OMIM: 601510) PREDICTED: sterol regu (1279) 8711 1104.4       0
XP_005265024 (OMIM: 601510) PREDICTED: sterol regu (1278) 8692 1102.0       0
XP_016861408 (OMIM: 601510) PREDICTED: sterol regu (1049) 7120 905.1       0
XP_016861409 (OMIM: 601510) PREDICTED: sterol regu (1048) 7101 902.8       0
XP_005265025 (OMIM: 601510) PREDICTED: sterol regu (1024) 6961 885.2       0
NP_001306973 (OMIM: 601510) sterol regulatory elem (1023) 6942 882.8       0
XP_011531804 (OMIM: 601510) PREDICTED: sterol regu ( 898) 6163 785.3       0
XP_005265028 (OMIM: 601510) PREDICTED: sterol regu ( 887) 6104 777.9       0
XP_016861410 (OMIM: 601510) PREDICTED: sterol regu ( 886) 6085 775.5       0
XP_011530390 (OMIM: 606278) PREDICTED: F-box/WD re ( 540)  299 51.0 2.7e-05
NP_001013433 (OMIM: 606278) F-box/WD repeat-contai ( 589)  299 51.0 2.8e-05
NP_060785 (OMIM: 606278) F-box/WD repeat-containin ( 627)  299 51.0   3e-05
XP_011530389 (OMIM: 606278) PREDICTED: F-box/WD re ( 679)  299 51.1 3.1e-05
XP_011530388 (OMIM: 606278) PREDICTED: F-box/WD re ( 679)  299 51.1 3.1e-05
XP_016863851 (OMIM: 606278) PREDICTED: F-box/WD re ( 707)  299 51.1 3.2e-05
XP_011530386 (OMIM: 606278) PREDICTED: F-box/WD re ( 707)  299 51.1 3.2e-05
NP_361014 (OMIM: 606278) F-box/WD repeat-containin ( 707)  299 51.1 3.2e-05
XP_011530387 (OMIM: 606278) PREDICTED: F-box/WD re ( 707)  299 51.1 3.2e-05
XP_011530385 (OMIM: 606278) PREDICTED: F-box/WD re ( 707)  299 51.1 3.2e-05
XP_011524317 (OMIM: 257220,607623) PREDICTED: Niem (1148)  277 48.5 0.00031
XP_016881276 (OMIM: 257220,607623) PREDICTED: Niem (1256)  277 48.6 0.00033
XP_016881275 (OMIM: 257220,607623) PREDICTED: Niem (1264)  277 48.6 0.00033
XP_016881274 (OMIM: 257220,607623) PREDICTED: Niem (1273)  277 48.6 0.00034
XP_006722542 (OMIM: 257220,607623) PREDICTED: Niem (1273)  277 48.6 0.00034
NP_000262 (OMIM: 257220,607623) Niemann-Pick C1 pr (1278)  277 48.6 0.00034
XP_016881273 (OMIM: 257220,607623) PREDICTED: Niem (1281)  277 48.6 0.00034
XP_005258336 (OMIM: 257220,607623) PREDICTED: Niem (1286)  277 48.6 0.00034
XP_005258335 (OMIM: 257220,607623) PREDICTED: Niem (1295)  277 48.6 0.00034
XP_005258334 (OMIM: 257220,607623) PREDICTED: Niem (1303)  277 48.6 0.00034
XP_005272220 (OMIM: 609012) PREDICTED: WD repeat-c ( 334)  258 45.7 0.00066
NP_438172 (OMIM: 609012) WD repeat-containing prot ( 334)  258 45.7 0.00066
NP_060058 (OMIM: 609012) WD repeat-containing prot ( 334)  258 45.7 0.00066
XP_011513630 (OMIM: 608010) PREDICTED: Niemann-Pic ( 785)  254 45.5  0.0017
NP_001095118 (OMIM: 608010) Niemann-Pick C1-like p (1332)  254 45.7  0.0025
NP_037521 (OMIM: 608010) Niemann-Pick C1-like prot (1359)  254 45.7  0.0026
NP_001077074 (OMIM: 109400,601309,605462,610828) p (1296)  243 44.3  0.0065
NP_001077075 (OMIM: 109400,601309,605462,610828) p (1296)  243 44.3  0.0065
NP_001077073 (OMIM: 109400,601309,605462,610828) p (1296)  243 44.3  0.0065
NP_001077076 (OMIM: 109400,601309,605462,610828) p (1296)  243 44.3  0.0065
NP_001077071 (OMIM: 109400,601309,605462,610828) p (1381)  243 44.3  0.0068
NP_001077072 (OMIM: 109400,601309,605462,610828) p (1446)  243 44.4   0.007
NP_000255 (OMIM: 109400,601309,605462,610828) prot (1447)  243 44.4   0.007
NP_001159764 (OMIM: 109400,155255,603673,605462) p (1146)  238 43.6  0.0092
NP_003729 (OMIM: 109400,155255,603673,605462) prot (1203)  238 43.7  0.0095


>>NP_036367 (OMIM: 601510) sterol regulatory element-bin  (1279 aa)
 initn: 8711 init1: 8711 opt: 8711  Z-score: 5902.5  bits: 1104.4 E(85289):    0
Smith-Waterman score: 8711; 100.0% identity (100.0% similar) in 1279 aa overlap (1-1279:1-1279)

               10        20        30        40        50        60
pF1KSD MTLTERLREKISRAFYNHGLLCASYPIPIILFTGFCILACCYPLLKLPLPGTGPVEFTTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MTLTERLREKISRAFYNHGLLCASYPIPIILFTGFCILACCYPLLKLPLPGTGPVEFTTP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD VKDYSPPPVDSDRKQGEPTEQPEWYVGAPVAYVQQIFVKSSVFPWHKNLLAVDVFRSPLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 VKDYSPPPVDSDRKQGEPTEQPEWYVGAPVAYVQQIFVKSSVFPWHKNLLAVDVFRSPLS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD RAFQLVEEIRNHVLRDSSGIRSLEELCLQVTDLLPGLRKLRNLLPEHGCLLLSPGNFWQN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 RAFQLVEEIRNHVLRDSSGIRSLEELCLQVTDLLPGLRKLRNLLPEHGCLLLSPGNFWQN
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD DWERFHADPDIIGTIHQHEPKTLQTSATLKDLLFGVPGKYSGVSLYTRKRMVSYTITLVF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 DWERFHADPDIIGTIHQHEPKTLQTSATLKDLLFGVPGKYSGVSLYTRKRMVSYTITLVF
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD QHYHAKFLGSLRARLMLLHPSPNCSLRAESLVHVHFKEEIGVAELIPLVTTYIILFAYIY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 QHYHAKFLGSLRARLMLLHPSPNCSLRAESLVHVHFKEEIGVAELIPLVTTYIILFAYIY
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD FSTRKIDMVKSKWGLALAAVVTVLSSLLMSVGLCTLFGLTPTLNGGEIFPYLVVVIGLEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 FSTRKIDMVKSKWGLALAAVVTVLSSLLMSVGLCTLFGLTPTLNGGEIFPYLVVVIGLEN
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD VLVLTKSVVSTPVDLEVKLRIAQGLSSESWSIMKNMATELGIILIGYFTLVPAIQEFCLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 VLVLTKSVVSTPVDLEVKLRIAQGLSSESWSIMKNMATELGIILIGYFTLVPAIQEFCLF
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD AVVGLVSDFFLQMLFFTTVLSIDIRRMELADLNKRLPPEACLPSAKPVGQPTRYERQLAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 AVVGLVSDFFLQMLFFTTVLSIDIRRMELADLNKRLPPEACLPSAKPVGQPTRYERQLAV
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD RPSTPHTITLQPSSFRNLRLPKRLRVVYFLARTRLAQRLIMAGTVVWIGILVYTDPAGLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 RPSTPHTITLQPSSFRNLRLPKRLRVVYFLARTRLAQRLIMAGTVVWIGILVYTDPAGLR
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD NYLAAQVTEQSPLGEGALAPMPVPSGMLPPSHPDPAFSIFPPDAPKLPENQTSPGESPER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 NYLAAQVTEQSPLGEGALAPMPVPSGMLPPSHPDPAFSIFPPDAPKLPENQTSPGESPER
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD GGPAEVVHDSPVPEVTWGPEDEELWRKLSFRHWPTLFSYYNITLAKRYISLLPVIPVTLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 GGPAEVVHDSPVPEVTWGPEDEELWRKLSFRHWPTLFSYYNITLAKRYISLLPVIPVTLR
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD LNPREALEGRHPQDGRSAWPPPGPIPAGHWEAGPKGPGGVQAHGDVTLYKVAALGLATGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 LNPREALEGRHPQDGRSAWPPPGPIPAGHWEAGPKGPGGVQAHGDVTLYKVAALGLATGI
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD VLVLLLLCLYRVLCPRNYGQLGGGPGRRRRGELPCDDYGYAPPETEIVPLVLRGHLMDIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 VLVLLLLCLYRVLCPRNYGQLGGGPGRRRRGELPCDDYGYAPPETEIVPLVLRGHLMDIE
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KSD CLASDGMLLVSCCLAGHVCVWDAQTGDCLTRIPRPGRQRRDSGVGSGLEAQESWERLSDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 CLASDGMLLVSCCLAGHVCVWDAQTGDCLTRIPRPGRQRRDSGVGSGLEAQESWERLSDG
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KSD GKAGPEEPGDSPPLRHRPRGPPPPSLFGDQPDLTCLIDTNFSAQPRSSQPTQPEPRHRAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 GKAGPEEPGDSPPLRHRPRGPPPPSLFGDQPDLTCLIDTNFSAQPRSSQPTQPEPRHRAV
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KSD CGRSRDSPGYDFSCLVQRVYQEEGLAAVCTPALRPPSPGPVLSQAPEDEGGSPEKGSPSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 CGRSRDSPGYDFSCLVQRVYQEEGLAAVCTPALRPPSPGPVLSQAPEDEGGSPEKGSPSL
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KSD AWAPSAEGSIWSLELQGNLIVVGRSSGRLEVWDAIEGVLCCSSEEVSSGITALVFLDKRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 AWAPSAEGSIWSLELQGNLIVVGRSSGRLEVWDAIEGVLCCSSEEVSSGITALVFLDKRI
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KSD VAARLNGSLDFFSLETHTALSPLQFRGTPGRGSSPASPVYSSSDTVACHLTHTVPCAHQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 VAARLNGSLDFFSLETHTALSPLQFRGTPGRGSSPASPVYSSSDTVACHLTHTVPCAHQK
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KSD PITALKAAAGRLVTGSQDHTLRVFRLEDSCCLFTLQGHSGAITTVYIDQTMVLASGGQDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 PITALKAAAGRLVTGSQDHTLRVFRLEDSCCLFTLQGHSGAITTVYIDQTMVLASGGQDG
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KSD AICLWDVLTGSRVSHVFAHRGDVTSLTCTTSCVISSGLDDLISIWDRSTGIKFYSIQQDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 AICLWDVLTGSRVSHVFAHRGDVTSLTCTTSCVISSGLDDLISIWDRSTGIKFYSIQQDL
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KSD GCGASLGVISDNLLVTGGQGCVSFWDLNYGDLLQTVYLGKNSEAQPARQILVLDNAAIVC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 GCGASLGVISDNLLVTGGQGCVSFWDLNYGDLLQTVYLGKNSEAQPARQILVLDNAAIVC
             1210      1220      1230      1240      1250      1260

             1270         
pF1KSD NFGSELSLVYVPSVLEKLD
       :::::::::::::::::::
NP_036 NFGSELSLVYVPSVLEKLD
             1270         

>>XP_016861407 (OMIM: 601510) PREDICTED: sterol regulato  (1279 aa)
 initn: 8711 init1: 8711 opt: 8711  Z-score: 5902.5  bits: 1104.4 E(85289):    0
Smith-Waterman score: 8711; 100.0% identity (100.0% similar) in 1279 aa overlap (1-1279:1-1279)

               10        20        30        40        50        60
pF1KSD MTLTERLREKISRAFYNHGLLCASYPIPIILFTGFCILACCYPLLKLPLPGTGPVEFTTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MTLTERLREKISRAFYNHGLLCASYPIPIILFTGFCILACCYPLLKLPLPGTGPVEFTTP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD VKDYSPPPVDSDRKQGEPTEQPEWYVGAPVAYVQQIFVKSSVFPWHKNLLAVDVFRSPLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKDYSPPPVDSDRKQGEPTEQPEWYVGAPVAYVQQIFVKSSVFPWHKNLLAVDVFRSPLS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD RAFQLVEEIRNHVLRDSSGIRSLEELCLQVTDLLPGLRKLRNLLPEHGCLLLSPGNFWQN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RAFQLVEEIRNHVLRDSSGIRSLEELCLQVTDLLPGLRKLRNLLPEHGCLLLSPGNFWQN
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD DWERFHADPDIIGTIHQHEPKTLQTSATLKDLLFGVPGKYSGVSLYTRKRMVSYTITLVF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DWERFHADPDIIGTIHQHEPKTLQTSATLKDLLFGVPGKYSGVSLYTRKRMVSYTITLVF
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD QHYHAKFLGSLRARLMLLHPSPNCSLRAESLVHVHFKEEIGVAELIPLVTTYIILFAYIY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QHYHAKFLGSLRARLMLLHPSPNCSLRAESLVHVHFKEEIGVAELIPLVTTYIILFAYIY
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD FSTRKIDMVKSKWGLALAAVVTVLSSLLMSVGLCTLFGLTPTLNGGEIFPYLVVVIGLEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSTRKIDMVKSKWGLALAAVVTVLSSLLMSVGLCTLFGLTPTLNGGEIFPYLVVVIGLEN
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD VLVLTKSVVSTPVDLEVKLRIAQGLSSESWSIMKNMATELGIILIGYFTLVPAIQEFCLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLVLTKSVVSTPVDLEVKLRIAQGLSSESWSIMKNMATELGIILIGYFTLVPAIQEFCLF
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD AVVGLVSDFFLQMLFFTTVLSIDIRRMELADLNKRLPPEACLPSAKPVGQPTRYERQLAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVVGLVSDFFLQMLFFTTVLSIDIRRMELADLNKRLPPEACLPSAKPVGQPTRYERQLAV
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD RPSTPHTITLQPSSFRNLRLPKRLRVVYFLARTRLAQRLIMAGTVVWIGILVYTDPAGLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RPSTPHTITLQPSSFRNLRLPKRLRVVYFLARTRLAQRLIMAGTVVWIGILVYTDPAGLR
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD NYLAAQVTEQSPLGEGALAPMPVPSGMLPPSHPDPAFSIFPPDAPKLPENQTSPGESPER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NYLAAQVTEQSPLGEGALAPMPVPSGMLPPSHPDPAFSIFPPDAPKLPENQTSPGESPER
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD GGPAEVVHDSPVPEVTWGPEDEELWRKLSFRHWPTLFSYYNITLAKRYISLLPVIPVTLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGPAEVVHDSPVPEVTWGPEDEELWRKLSFRHWPTLFSYYNITLAKRYISLLPVIPVTLR
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD LNPREALEGRHPQDGRSAWPPPGPIPAGHWEAGPKGPGGVQAHGDVTLYKVAALGLATGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNPREALEGRHPQDGRSAWPPPGPIPAGHWEAGPKGPGGVQAHGDVTLYKVAALGLATGI
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD VLVLLLLCLYRVLCPRNYGQLGGGPGRRRRGELPCDDYGYAPPETEIVPLVLRGHLMDIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLVLLLLCLYRVLCPRNYGQLGGGPGRRRRGELPCDDYGYAPPETEIVPLVLRGHLMDIE
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KSD CLASDGMLLVSCCLAGHVCVWDAQTGDCLTRIPRPGRQRRDSGVGSGLEAQESWERLSDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLASDGMLLVSCCLAGHVCVWDAQTGDCLTRIPRPGRQRRDSGVGSGLEAQESWERLSDG
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KSD GKAGPEEPGDSPPLRHRPRGPPPPSLFGDQPDLTCLIDTNFSAQPRSSQPTQPEPRHRAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKAGPEEPGDSPPLRHRPRGPPPPSLFGDQPDLTCLIDTNFSAQPRSSQPTQPEPRHRAV
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KSD CGRSRDSPGYDFSCLVQRVYQEEGLAAVCTPALRPPSPGPVLSQAPEDEGGSPEKGSPSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CGRSRDSPGYDFSCLVQRVYQEEGLAAVCTPALRPPSPGPVLSQAPEDEGGSPEKGSPSL
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KSD AWAPSAEGSIWSLELQGNLIVVGRSSGRLEVWDAIEGVLCCSSEEVSSGITALVFLDKRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AWAPSAEGSIWSLELQGNLIVVGRSSGRLEVWDAIEGVLCCSSEEVSSGITALVFLDKRI
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KSD VAARLNGSLDFFSLETHTALSPLQFRGTPGRGSSPASPVYSSSDTVACHLTHTVPCAHQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAARLNGSLDFFSLETHTALSPLQFRGTPGRGSSPASPVYSSSDTVACHLTHTVPCAHQK
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KSD PITALKAAAGRLVTGSQDHTLRVFRLEDSCCLFTLQGHSGAITTVYIDQTMVLASGGQDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PITALKAAAGRLVTGSQDHTLRVFRLEDSCCLFTLQGHSGAITTVYIDQTMVLASGGQDG
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KSD AICLWDVLTGSRVSHVFAHRGDVTSLTCTTSCVISSGLDDLISIWDRSTGIKFYSIQQDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AICLWDVLTGSRVSHVFAHRGDVTSLTCTTSCVISSGLDDLISIWDRSTGIKFYSIQQDL
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KSD GCGASLGVISDNLLVTGGQGCVSFWDLNYGDLLQTVYLGKNSEAQPARQILVLDNAAIVC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GCGASLGVISDNLLVTGGQGCVSFWDLNYGDLLQTVYLGKNSEAQPARQILVLDNAAIVC
             1210      1220      1230      1240      1250      1260

             1270         
pF1KSD NFGSELSLVYVPSVLEKLD
       :::::::::::::::::::
XP_016 NFGSELSLVYVPSVLEKLD
             1270         

>>XP_011531803 (OMIM: 601510) PREDICTED: sterol regulato  (1279 aa)
 initn: 8711 init1: 8711 opt: 8711  Z-score: 5902.5  bits: 1104.4 E(85289):    0
Smith-Waterman score: 8711; 100.0% identity (100.0% similar) in 1279 aa overlap (1-1279:1-1279)

               10        20        30        40        50        60
pF1KSD MTLTERLREKISRAFYNHGLLCASYPIPIILFTGFCILACCYPLLKLPLPGTGPVEFTTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MTLTERLREKISRAFYNHGLLCASYPIPIILFTGFCILACCYPLLKLPLPGTGPVEFTTP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD VKDYSPPPVDSDRKQGEPTEQPEWYVGAPVAYVQQIFVKSSVFPWHKNLLAVDVFRSPLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKDYSPPPVDSDRKQGEPTEQPEWYVGAPVAYVQQIFVKSSVFPWHKNLLAVDVFRSPLS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD RAFQLVEEIRNHVLRDSSGIRSLEELCLQVTDLLPGLRKLRNLLPEHGCLLLSPGNFWQN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RAFQLVEEIRNHVLRDSSGIRSLEELCLQVTDLLPGLRKLRNLLPEHGCLLLSPGNFWQN
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD DWERFHADPDIIGTIHQHEPKTLQTSATLKDLLFGVPGKYSGVSLYTRKRMVSYTITLVF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DWERFHADPDIIGTIHQHEPKTLQTSATLKDLLFGVPGKYSGVSLYTRKRMVSYTITLVF
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD QHYHAKFLGSLRARLMLLHPSPNCSLRAESLVHVHFKEEIGVAELIPLVTTYIILFAYIY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QHYHAKFLGSLRARLMLLHPSPNCSLRAESLVHVHFKEEIGVAELIPLVTTYIILFAYIY
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD FSTRKIDMVKSKWGLALAAVVTVLSSLLMSVGLCTLFGLTPTLNGGEIFPYLVVVIGLEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FSTRKIDMVKSKWGLALAAVVTVLSSLLMSVGLCTLFGLTPTLNGGEIFPYLVVVIGLEN
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD VLVLTKSVVSTPVDLEVKLRIAQGLSSESWSIMKNMATELGIILIGYFTLVPAIQEFCLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLVLTKSVVSTPVDLEVKLRIAQGLSSESWSIMKNMATELGIILIGYFTLVPAIQEFCLF
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD AVVGLVSDFFLQMLFFTTVLSIDIRRMELADLNKRLPPEACLPSAKPVGQPTRYERQLAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVVGLVSDFFLQMLFFTTVLSIDIRRMELADLNKRLPPEACLPSAKPVGQPTRYERQLAV
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD RPSTPHTITLQPSSFRNLRLPKRLRVVYFLARTRLAQRLIMAGTVVWIGILVYTDPAGLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RPSTPHTITLQPSSFRNLRLPKRLRVVYFLARTRLAQRLIMAGTVVWIGILVYTDPAGLR
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD NYLAAQVTEQSPLGEGALAPMPVPSGMLPPSHPDPAFSIFPPDAPKLPENQTSPGESPER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NYLAAQVTEQSPLGEGALAPMPVPSGMLPPSHPDPAFSIFPPDAPKLPENQTSPGESPER
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD GGPAEVVHDSPVPEVTWGPEDEELWRKLSFRHWPTLFSYYNITLAKRYISLLPVIPVTLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGPAEVVHDSPVPEVTWGPEDEELWRKLSFRHWPTLFSYYNITLAKRYISLLPVIPVTLR
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD LNPREALEGRHPQDGRSAWPPPGPIPAGHWEAGPKGPGGVQAHGDVTLYKVAALGLATGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNPREALEGRHPQDGRSAWPPPGPIPAGHWEAGPKGPGGVQAHGDVTLYKVAALGLATGI
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD VLVLLLLCLYRVLCPRNYGQLGGGPGRRRRGELPCDDYGYAPPETEIVPLVLRGHLMDIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLVLLLLCLYRVLCPRNYGQLGGGPGRRRRGELPCDDYGYAPPETEIVPLVLRGHLMDIE
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KSD CLASDGMLLVSCCLAGHVCVWDAQTGDCLTRIPRPGRQRRDSGVGSGLEAQESWERLSDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CLASDGMLLVSCCLAGHVCVWDAQTGDCLTRIPRPGRQRRDSGVGSGLEAQESWERLSDG
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KSD GKAGPEEPGDSPPLRHRPRGPPPPSLFGDQPDLTCLIDTNFSAQPRSSQPTQPEPRHRAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GKAGPEEPGDSPPLRHRPRGPPPPSLFGDQPDLTCLIDTNFSAQPRSSQPTQPEPRHRAV
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KSD CGRSRDSPGYDFSCLVQRVYQEEGLAAVCTPALRPPSPGPVLSQAPEDEGGSPEKGSPSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CGRSRDSPGYDFSCLVQRVYQEEGLAAVCTPALRPPSPGPVLSQAPEDEGGSPEKGSPSL
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KSD AWAPSAEGSIWSLELQGNLIVVGRSSGRLEVWDAIEGVLCCSSEEVSSGITALVFLDKRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AWAPSAEGSIWSLELQGNLIVVGRSSGRLEVWDAIEGVLCCSSEEVSSGITALVFLDKRI
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KSD VAARLNGSLDFFSLETHTALSPLQFRGTPGRGSSPASPVYSSSDTVACHLTHTVPCAHQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VAARLNGSLDFFSLETHTALSPLQFRGTPGRGSSPASPVYSSSDTVACHLTHTVPCAHQK
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KSD PITALKAAAGRLVTGSQDHTLRVFRLEDSCCLFTLQGHSGAITTVYIDQTMVLASGGQDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PITALKAAAGRLVTGSQDHTLRVFRLEDSCCLFTLQGHSGAITTVYIDQTMVLASGGQDG
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KSD AICLWDVLTGSRVSHVFAHRGDVTSLTCTTSCVISSGLDDLISIWDRSTGIKFYSIQQDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AICLWDVLTGSRVSHVFAHRGDVTSLTCTTSCVISSGLDDLISIWDRSTGIKFYSIQQDL
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KSD GCGASLGVISDNLLVTGGQGCVSFWDLNYGDLLQTVYLGKNSEAQPARQILVLDNAAIVC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GCGASLGVISDNLLVTGGQGCVSFWDLNYGDLLQTVYLGKNSEAQPARQILVLDNAAIVC
             1210      1220      1230      1240      1250      1260

             1270         
pF1KSD NFGSELSLVYVPSVLEKLD
       :::::::::::::::::::
XP_011 NFGSELSLVYVPSVLEKLD
             1270         

>>XP_005265024 (OMIM: 601510) PREDICTED: sterol regulato  (1278 aa)
 initn: 5619 init1: 5566 opt: 8692  Z-score: 5889.7  bits: 1102.0 E(85289):    0
Smith-Waterman score: 8692; 99.9% identity (99.9% similar) in 1279 aa overlap (1-1279:1-1278)

               10        20        30        40        50        60
pF1KSD MTLTERLREKISRAFYNHGLLCASYPIPIILFTGFCILACCYPLLKLPLPGTGPVEFTTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MTLTERLREKISRAFYNHGLLCASYPIPIILFTGFCILACCYPLLKLPLPGTGPVEFTTP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD VKDYSPPPVDSDRKQGEPTEQPEWYVGAPVAYVQQIFVKSSVFPWHKNLLAVDVFRSPLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VKDYSPPPVDSDRKQGEPTEQPEWYVGAPVAYVQQIFVKSSVFPWHKNLLAVDVFRSPLS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD RAFQLVEEIRNHVLRDSSGIRSLEELCLQVTDLLPGLRKLRNLLPEHGCLLLSPGNFWQN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RAFQLVEEIRNHVLRDSSGIRSLEELCLQVTDLLPGLRKLRNLLPEHGCLLLSPGNFWQN
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD DWERFHADPDIIGTIHQHEPKTLQTSATLKDLLFGVPGKYSGVSLYTRKRMVSYTITLVF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DWERFHADPDIIGTIHQHEPKTLQTSATLKDLLFGVPGKYSGVSLYTRKRMVSYTITLVF
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD QHYHAKFLGSLRARLMLLHPSPNCSLRAESLVHVHFKEEIGVAELIPLVTTYIILFAYIY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QHYHAKFLGSLRARLMLLHPSPNCSLRAESLVHVHFKEEIGVAELIPLVTTYIILFAYIY
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD FSTRKIDMVKSKWGLALAAVVTVLSSLLMSVGLCTLFGLTPTLNGGEIFPYLVVVIGLEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FSTRKIDMVKSKWGLALAAVVTVLSSLLMSVGLCTLFGLTPTLNGGEIFPYLVVVIGLEN
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD VLVLTKSVVSTPVDLEVKLRIAQGLSSESWSIMKNMATELGIILIGYFTLVPAIQEFCLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VLVLTKSVVSTPVDLEVKLRIAQGLSSESWSIMKNMATELGIILIGYFTLVPAIQEFCLF
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD AVVGLVSDFFLQMLFFTTVLSIDIRRMELADLNKRLPPEACLPSAKPVGQPTRYERQLAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AVVGLVSDFFLQMLFFTTVLSIDIRRMELADLNKRLPPEACLPSAKPVGQPTRYERQLAV
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD RPSTPHTITLQPSSFRNLRLPKRLRVVYFLARTRLAQRLIMAGTVVWIGILVYTDPAGLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RPSTPHTITLQPSSFRNLRLPKRLRVVYFLARTRLAQRLIMAGTVVWIGILVYTDPAGLR
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD NYLAAQVTEQSPLGEGALAPMPVPSGMLPPSHPDPAFSIFPPDAPKLPENQTSPGESPER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NYLAAQVTEQSPLGEGALAPMPVPSGMLPPSHPDPAFSIFPPDAPKLPENQTSPGESPER
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD GGPAEVVHDSPVPEVTWGPEDEELWRKLSFRHWPTLFSYYNITLAKRYISLLPVIPVTLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GGPAEVVHDSPVPEVTWGPEDEELWRKLSFRHWPTLFSYYNITLAKRYISLLPVIPVTLR
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD LNPREALEGRHPQDGRSAWPPPGPIPAGHWEAGPKGPGGVQAHGDVTLYKVAALGLATGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LNPREALEGRHPQDGRSAWPPPGPIPAGHWEAGPKGPGGVQAHGDVTLYKVAALGLATGI
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD VLVLLLLCLYRVLCPRNYGQLGGGPGRRRRGELPCDDYGYAPPETEIVPLVLRGHLMDIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VLVLLLLCLYRVLCPRNYGQLGGGPGRRRRGELPCDDYGYAPPETEIVPLVLRGHLMDIE
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KSD CLASDGMLLVSCCLAGHVCVWDAQTGDCLTRIPRPGRQRRDSGVGSGLEAQESWERLSDG
       :::::::::::::::::::::::::::::::::::: :::::::::::::::::::::::
XP_005 CLASDGMLLVSCCLAGHVCVWDAQTGDCLTRIPRPG-QRRDSGVGSGLEAQESWERLSDG
              790       800       810        820       830         

              850       860       870       880       890       900
pF1KSD GKAGPEEPGDSPPLRHRPRGPPPPSLFGDQPDLTCLIDTNFSAQPRSSQPTQPEPRHRAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GKAGPEEPGDSPPLRHRPRGPPPPSLFGDQPDLTCLIDTNFSAQPRSSQPTQPEPRHRAV
     840       850       860       870       880       890         

              910       920       930       940       950       960
pF1KSD CGRSRDSPGYDFSCLVQRVYQEEGLAAVCTPALRPPSPGPVLSQAPEDEGGSPEKGSPSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CGRSRDSPGYDFSCLVQRVYQEEGLAAVCTPALRPPSPGPVLSQAPEDEGGSPEKGSPSL
     900       910       920       930       940       950         

              970       980       990      1000      1010      1020
pF1KSD AWAPSAEGSIWSLELQGNLIVVGRSSGRLEVWDAIEGVLCCSSEEVSSGITALVFLDKRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AWAPSAEGSIWSLELQGNLIVVGRSSGRLEVWDAIEGVLCCSSEEVSSGITALVFLDKRI
     960       970       980       990      1000      1010         

             1030      1040      1050      1060      1070      1080
pF1KSD VAARLNGSLDFFSLETHTALSPLQFRGTPGRGSSPASPVYSSSDTVACHLTHTVPCAHQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VAARLNGSLDFFSLETHTALSPLQFRGTPGRGSSPASPVYSSSDTVACHLTHTVPCAHQK
    1020      1030      1040      1050      1060      1070         

             1090      1100      1110      1120      1130      1140
pF1KSD PITALKAAAGRLVTGSQDHTLRVFRLEDSCCLFTLQGHSGAITTVYIDQTMVLASGGQDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PITALKAAAGRLVTGSQDHTLRVFRLEDSCCLFTLQGHSGAITTVYIDQTMVLASGGQDG
    1080      1090      1100      1110      1120      1130         

             1150      1160      1170      1180      1190      1200
pF1KSD AICLWDVLTGSRVSHVFAHRGDVTSLTCTTSCVISSGLDDLISIWDRSTGIKFYSIQQDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AICLWDVLTGSRVSHVFAHRGDVTSLTCTTSCVISSGLDDLISIWDRSTGIKFYSIQQDL
    1140      1150      1160      1170      1180      1190         

             1210      1220      1230      1240      1250      1260
pF1KSD GCGASLGVISDNLLVTGGQGCVSFWDLNYGDLLQTVYLGKNSEAQPARQILVLDNAAIVC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GCGASLGVISDNLLVTGGQGCVSFWDLNYGDLLQTVYLGKNSEAQPARQILVLDNAAIVC
    1200      1210      1220      1230      1240      1250         

             1270         
pF1KSD NFGSELSLVYVPSVLEKLD
       :::::::::::::::::::
XP_005 NFGSELSLVYVPSVLEKLD
    1260      1270        

>>XP_016861408 (OMIM: 601510) PREDICTED: sterol regulato  (1049 aa)
 initn: 7120 init1: 7120 opt: 7120  Z-score: 4827.2  bits: 905.1 E(85289):    0
Smith-Waterman score: 7120; 100.0% identity (100.0% similar) in 1049 aa overlap (231-1279:1-1049)

              210       220       230       240       250       260
pF1KSD KTLQTSATLKDLLFGVPGKYSGVSLYTRKRMVSYTITLVFQHYHAKFLGSLRARLMLLHP
                                     ::::::::::::::::::::::::::::::
XP_016                               MVSYTITLVFQHYHAKFLGSLRARLMLLHP
                                             10        20        30

              270       280       290       300       310       320
pF1KSD SPNCSLRAESLVHVHFKEEIGVAELIPLVTTYIILFAYIYFSTRKIDMVKSKWGLALAAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPNCSLRAESLVHVHFKEEIGVAELIPLVTTYIILFAYIYFSTRKIDMVKSKWGLALAAV
               40        50        60        70        80        90

              330       340       350       360       370       380
pF1KSD VTVLSSLLMSVGLCTLFGLTPTLNGGEIFPYLVVVIGLENVLVLTKSVVSTPVDLEVKLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTVLSSLLMSVGLCTLFGLTPTLNGGEIFPYLVVVIGLENVLVLTKSVVSTPVDLEVKLR
              100       110       120       130       140       150

              390       400       410       420       430       440
pF1KSD IAQGLSSESWSIMKNMATELGIILIGYFTLVPAIQEFCLFAVVGLVSDFFLQMLFFTTVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IAQGLSSESWSIMKNMATELGIILIGYFTLVPAIQEFCLFAVVGLVSDFFLQMLFFTTVL
              160       170       180       190       200       210

              450       460       470       480       490       500
pF1KSD SIDIRRMELADLNKRLPPEACLPSAKPVGQPTRYERQLAVRPSTPHTITLQPSSFRNLRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SIDIRRMELADLNKRLPPEACLPSAKPVGQPTRYERQLAVRPSTPHTITLQPSSFRNLRL
              220       230       240       250       260       270

              510       520       530       540       550       560
pF1KSD PKRLRVVYFLARTRLAQRLIMAGTVVWIGILVYTDPAGLRNYLAAQVTEQSPLGEGALAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PKRLRVVYFLARTRLAQRLIMAGTVVWIGILVYTDPAGLRNYLAAQVTEQSPLGEGALAP
              280       290       300       310       320       330

              570       580       590       600       610       620
pF1KSD MPVPSGMLPPSHPDPAFSIFPPDAPKLPENQTSPGESPERGGPAEVVHDSPVPEVTWGPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MPVPSGMLPPSHPDPAFSIFPPDAPKLPENQTSPGESPERGGPAEVVHDSPVPEVTWGPE
              340       350       360       370       380       390

              630       640       650       660       670       680
pF1KSD DEELWRKLSFRHWPTLFSYYNITLAKRYISLLPVIPVTLRLNPREALEGRHPQDGRSAWP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DEELWRKLSFRHWPTLFSYYNITLAKRYISLLPVIPVTLRLNPREALEGRHPQDGRSAWP
              400       410       420       430       440       450

              690       700       710       720       730       740
pF1KSD PPGPIPAGHWEAGPKGPGGVQAHGDVTLYKVAALGLATGIVLVLLLLCLYRVLCPRNYGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPGPIPAGHWEAGPKGPGGVQAHGDVTLYKVAALGLATGIVLVLLLLCLYRVLCPRNYGQ
              460       470       480       490       500       510

              750       760       770       780       790       800
pF1KSD LGGGPGRRRRGELPCDDYGYAPPETEIVPLVLRGHLMDIECLASDGMLLVSCCLAGHVCV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGGGPGRRRRGELPCDDYGYAPPETEIVPLVLRGHLMDIECLASDGMLLVSCCLAGHVCV
              520       530       540       550       560       570

              810       820       830       840       850       860
pF1KSD WDAQTGDCLTRIPRPGRQRRDSGVGSGLEAQESWERLSDGGKAGPEEPGDSPPLRHRPRG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WDAQTGDCLTRIPRPGRQRRDSGVGSGLEAQESWERLSDGGKAGPEEPGDSPPLRHRPRG
              580       590       600       610       620       630

              870       880       890       900       910       920
pF1KSD PPPPSLFGDQPDLTCLIDTNFSAQPRSSQPTQPEPRHRAVCGRSRDSPGYDFSCLVQRVY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPPPSLFGDQPDLTCLIDTNFSAQPRSSQPTQPEPRHRAVCGRSRDSPGYDFSCLVQRVY
              640       650       660       670       680       690

              930       940       950       960       970       980
pF1KSD QEEGLAAVCTPALRPPSPGPVLSQAPEDEGGSPEKGSPSLAWAPSAEGSIWSLELQGNLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QEEGLAAVCTPALRPPSPGPVLSQAPEDEGGSPEKGSPSLAWAPSAEGSIWSLELQGNLI
              700       710       720       730       740       750

              990      1000      1010      1020      1030      1040
pF1KSD VVGRSSGRLEVWDAIEGVLCCSSEEVSSGITALVFLDKRIVAARLNGSLDFFSLETHTAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVGRSSGRLEVWDAIEGVLCCSSEEVSSGITALVFLDKRIVAARLNGSLDFFSLETHTAL
              760       770       780       790       800       810

             1050      1060      1070      1080      1090      1100
pF1KSD SPLQFRGTPGRGSSPASPVYSSSDTVACHLTHTVPCAHQKPITALKAAAGRLVTGSQDHT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPLQFRGTPGRGSSPASPVYSSSDTVACHLTHTVPCAHQKPITALKAAAGRLVTGSQDHT
              820       830       840       850       860       870

             1110      1120      1130      1140      1150      1160
pF1KSD LRVFRLEDSCCLFTLQGHSGAITTVYIDQTMVLASGGQDGAICLWDVLTGSRVSHVFAHR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRVFRLEDSCCLFTLQGHSGAITTVYIDQTMVLASGGQDGAICLWDVLTGSRVSHVFAHR
              880       890       900       910       920       930

             1170      1180      1190      1200      1210      1220
pF1KSD GDVTSLTCTTSCVISSGLDDLISIWDRSTGIKFYSIQQDLGCGASLGVISDNLLVTGGQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDVTSLTCTTSCVISSGLDDLISIWDRSTGIKFYSIQQDLGCGASLGVISDNLLVTGGQG
              940       950       960       970       980       990

             1230      1240      1250      1260      1270         
pF1KSD CVSFWDLNYGDLLQTVYLGKNSEAQPARQILVLDNAAIVCNFGSELSLVYVPSVLEKLD
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CVSFWDLNYGDLLQTVYLGKNSEAQPARQILVLDNAAIVCNFGSELSLVYVPSVLEKLD
             1000      1010      1020      1030      1040         

>>XP_016861409 (OMIM: 601510) PREDICTED: sterol regulato  (1048 aa)
 initn: 4028 init1: 3975 opt: 7101  Z-score: 4814.4  bits: 902.8 E(85289):    0
Smith-Waterman score: 7101; 99.9% identity (99.9% similar) in 1049 aa overlap (231-1279:1-1048)

              210       220       230       240       250       260
pF1KSD KTLQTSATLKDLLFGVPGKYSGVSLYTRKRMVSYTITLVFQHYHAKFLGSLRARLMLLHP
                                     ::::::::::::::::::::::::::::::
XP_016                               MVSYTITLVFQHYHAKFLGSLRARLMLLHP
                                             10        20        30

              270       280       290       300       310       320
pF1KSD SPNCSLRAESLVHVHFKEEIGVAELIPLVTTYIILFAYIYFSTRKIDMVKSKWGLALAAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPNCSLRAESLVHVHFKEEIGVAELIPLVTTYIILFAYIYFSTRKIDMVKSKWGLALAAV
               40        50        60        70        80        90

              330       340       350       360       370       380
pF1KSD VTVLSSLLMSVGLCTLFGLTPTLNGGEIFPYLVVVIGLENVLVLTKSVVSTPVDLEVKLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTVLSSLLMSVGLCTLFGLTPTLNGGEIFPYLVVVIGLENVLVLTKSVVSTPVDLEVKLR
              100       110       120       130       140       150

              390       400       410       420       430       440
pF1KSD IAQGLSSESWSIMKNMATELGIILIGYFTLVPAIQEFCLFAVVGLVSDFFLQMLFFTTVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IAQGLSSESWSIMKNMATELGIILIGYFTLVPAIQEFCLFAVVGLVSDFFLQMLFFTTVL
              160       170       180       190       200       210

              450       460       470       480       490       500
pF1KSD SIDIRRMELADLNKRLPPEACLPSAKPVGQPTRYERQLAVRPSTPHTITLQPSSFRNLRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SIDIRRMELADLNKRLPPEACLPSAKPVGQPTRYERQLAVRPSTPHTITLQPSSFRNLRL
              220       230       240       250       260       270

              510       520       530       540       550       560
pF1KSD PKRLRVVYFLARTRLAQRLIMAGTVVWIGILVYTDPAGLRNYLAAQVTEQSPLGEGALAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PKRLRVVYFLARTRLAQRLIMAGTVVWIGILVYTDPAGLRNYLAAQVTEQSPLGEGALAP
              280       290       300       310       320       330

              570       580       590       600       610       620
pF1KSD MPVPSGMLPPSHPDPAFSIFPPDAPKLPENQTSPGESPERGGPAEVVHDSPVPEVTWGPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MPVPSGMLPPSHPDPAFSIFPPDAPKLPENQTSPGESPERGGPAEVVHDSPVPEVTWGPE
              340       350       360       370       380       390

              630       640       650       660       670       680
pF1KSD DEELWRKLSFRHWPTLFSYYNITLAKRYISLLPVIPVTLRLNPREALEGRHPQDGRSAWP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DEELWRKLSFRHWPTLFSYYNITLAKRYISLLPVIPVTLRLNPREALEGRHPQDGRSAWP
              400       410       420       430       440       450

              690       700       710       720       730       740
pF1KSD PPGPIPAGHWEAGPKGPGGVQAHGDVTLYKVAALGLATGIVLVLLLLCLYRVLCPRNYGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPGPIPAGHWEAGPKGPGGVQAHGDVTLYKVAALGLATGIVLVLLLLCLYRVLCPRNYGQ
              460       470       480       490       500       510

              750       760       770       780       790       800
pF1KSD LGGGPGRRRRGELPCDDYGYAPPETEIVPLVLRGHLMDIECLASDGMLLVSCCLAGHVCV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGGGPGRRRRGELPCDDYGYAPPETEIVPLVLRGHLMDIECLASDGMLLVSCCLAGHVCV
              520       530       540       550       560       570

              810       820       830       840       850       860
pF1KSD WDAQTGDCLTRIPRPGRQRRDSGVGSGLEAQESWERLSDGGKAGPEEPGDSPPLRHRPRG
       :::::::::::::::: :::::::::::::::::::::::::::::::::::::::::::
XP_016 WDAQTGDCLTRIPRPG-QRRDSGVGSGLEAQESWERLSDGGKAGPEEPGDSPPLRHRPRG
              580        590       600       610       620         

              870       880       890       900       910       920
pF1KSD PPPPSLFGDQPDLTCLIDTNFSAQPRSSQPTQPEPRHRAVCGRSRDSPGYDFSCLVQRVY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPPPSLFGDQPDLTCLIDTNFSAQPRSSQPTQPEPRHRAVCGRSRDSPGYDFSCLVQRVY
     630       640       650       660       670       680         

              930       940       950       960       970       980
pF1KSD QEEGLAAVCTPALRPPSPGPVLSQAPEDEGGSPEKGSPSLAWAPSAEGSIWSLELQGNLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QEEGLAAVCTPALRPPSPGPVLSQAPEDEGGSPEKGSPSLAWAPSAEGSIWSLELQGNLI
     690       700       710       720       730       740         

              990      1000      1010      1020      1030      1040
pF1KSD VVGRSSGRLEVWDAIEGVLCCSSEEVSSGITALVFLDKRIVAARLNGSLDFFSLETHTAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVGRSSGRLEVWDAIEGVLCCSSEEVSSGITALVFLDKRIVAARLNGSLDFFSLETHTAL
     750       760       770       780       790       800         

             1050      1060      1070      1080      1090      1100
pF1KSD SPLQFRGTPGRGSSPASPVYSSSDTVACHLTHTVPCAHQKPITALKAAAGRLVTGSQDHT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPLQFRGTPGRGSSPASPVYSSSDTVACHLTHTVPCAHQKPITALKAAAGRLVTGSQDHT
     810       820       830       840       850       860         

             1110      1120      1130      1140      1150      1160
pF1KSD LRVFRLEDSCCLFTLQGHSGAITTVYIDQTMVLASGGQDGAICLWDVLTGSRVSHVFAHR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRVFRLEDSCCLFTLQGHSGAITTVYIDQTMVLASGGQDGAICLWDVLTGSRVSHVFAHR
     870       880       890       900       910       920         

             1170      1180      1190      1200      1210      1220
pF1KSD GDVTSLTCTTSCVISSGLDDLISIWDRSTGIKFYSIQQDLGCGASLGVISDNLLVTGGQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDVTSLTCTTSCVISSGLDDLISIWDRSTGIKFYSIQQDLGCGASLGVISDNLLVTGGQG
     930       940       950       960       970       980         

             1230      1240      1250      1260      1270         
pF1KSD CVSFWDLNYGDLLQTVYLGKNSEAQPARQILVLDNAAIVCNFGSELSLVYVPSVLEKLD
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CVSFWDLNYGDLLQTVYLGKNSEAQPARQILVLDNAAIVCNFGSELSLVYVPSVLEKLD
     990      1000      1010      1020      1030      1040        

>>XP_005265025 (OMIM: 601510) PREDICTED: sterol regulato  (1024 aa)
 initn: 6961 init1: 6961 opt: 6961  Z-score: 4719.8  bits: 885.2 E(85289):    0
Smith-Waterman score: 6961; 100.0% identity (100.0% similar) in 1024 aa overlap (256-1279:1-1024)

         230       240       250       260       270       280     
pF1KSD YTRKRMVSYTITLVFQHYHAKFLGSLRARLMLLHPSPNCSLRAESLVHVHFKEEIGVAEL
                                     ::::::::::::::::::::::::::::::
XP_005                               MLLHPSPNCSLRAESLVHVHFKEEIGVAEL
                                             10        20        30

         290       300       310       320       330       340     
pF1KSD IPLVTTYIILFAYIYFSTRKIDMVKSKWGLALAAVVTVLSSLLMSVGLCTLFGLTPTLNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IPLVTTYIILFAYIYFSTRKIDMVKSKWGLALAAVVTVLSSLLMSVGLCTLFGLTPTLNG
               40        50        60        70        80        90

         350       360       370       380       390       400     
pF1KSD GEIFPYLVVVIGLENVLVLTKSVVSTPVDLEVKLRIAQGLSSESWSIMKNMATELGIILI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GEIFPYLVVVIGLENVLVLTKSVVSTPVDLEVKLRIAQGLSSESWSIMKNMATELGIILI
              100       110       120       130       140       150

         410       420       430       440       450       460     
pF1KSD GYFTLVPAIQEFCLFAVVGLVSDFFLQMLFFTTVLSIDIRRMELADLNKRLPPEACLPSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GYFTLVPAIQEFCLFAVVGLVSDFFLQMLFFTTVLSIDIRRMELADLNKRLPPEACLPSA
              160       170       180       190       200       210

         470       480       490       500       510       520     
pF1KSD KPVGQPTRYERQLAVRPSTPHTITLQPSSFRNLRLPKRLRVVYFLARTRLAQRLIMAGTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KPVGQPTRYERQLAVRPSTPHTITLQPSSFRNLRLPKRLRVVYFLARTRLAQRLIMAGTV
              220       230       240       250       260       270

         530       540       550       560       570       580     
pF1KSD VWIGILVYTDPAGLRNYLAAQVTEQSPLGEGALAPMPVPSGMLPPSHPDPAFSIFPPDAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VWIGILVYTDPAGLRNYLAAQVTEQSPLGEGALAPMPVPSGMLPPSHPDPAFSIFPPDAP
              280       290       300       310       320       330

         590       600       610       620       630       640     
pF1KSD KLPENQTSPGESPERGGPAEVVHDSPVPEVTWGPEDEELWRKLSFRHWPTLFSYYNITLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KLPENQTSPGESPERGGPAEVVHDSPVPEVTWGPEDEELWRKLSFRHWPTLFSYYNITLA
              340       350       360       370       380       390

         650       660       670       680       690       700     
pF1KSD KRYISLLPVIPVTLRLNPREALEGRHPQDGRSAWPPPGPIPAGHWEAGPKGPGGVQAHGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KRYISLLPVIPVTLRLNPREALEGRHPQDGRSAWPPPGPIPAGHWEAGPKGPGGVQAHGD
              400       410       420       430       440       450

         710       720       730       740       750       760     
pF1KSD VTLYKVAALGLATGIVLVLLLLCLYRVLCPRNYGQLGGGPGRRRRGELPCDDYGYAPPET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VTLYKVAALGLATGIVLVLLLLCLYRVLCPRNYGQLGGGPGRRRRGELPCDDYGYAPPET
              460       470       480       490       500       510

         770       780       790       800       810       820     
pF1KSD EIVPLVLRGHLMDIECLASDGMLLVSCCLAGHVCVWDAQTGDCLTRIPRPGRQRRDSGVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EIVPLVLRGHLMDIECLASDGMLLVSCCLAGHVCVWDAQTGDCLTRIPRPGRQRRDSGVG
              520       530       540       550       560       570

         830       840       850       860       870       880     
pF1KSD SGLEAQESWERLSDGGKAGPEEPGDSPPLRHRPRGPPPPSLFGDQPDLTCLIDTNFSAQP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SGLEAQESWERLSDGGKAGPEEPGDSPPLRHRPRGPPPPSLFGDQPDLTCLIDTNFSAQP
              580       590       600       610       620       630

         890       900       910       920       930       940     
pF1KSD RSSQPTQPEPRHRAVCGRSRDSPGYDFSCLVQRVYQEEGLAAVCTPALRPPSPGPVLSQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RSSQPTQPEPRHRAVCGRSRDSPGYDFSCLVQRVYQEEGLAAVCTPALRPPSPGPVLSQA
              640       650       660       670       680       690

         950       960       970       980       990      1000     
pF1KSD PEDEGGSPEKGSPSLAWAPSAEGSIWSLELQGNLIVVGRSSGRLEVWDAIEGVLCCSSEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PEDEGGSPEKGSPSLAWAPSAEGSIWSLELQGNLIVVGRSSGRLEVWDAIEGVLCCSSEE
              700       710       720       730       740       750

        1010      1020      1030      1040      1050      1060     
pF1KSD VSSGITALVFLDKRIVAARLNGSLDFFSLETHTALSPLQFRGTPGRGSSPASPVYSSSDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VSSGITALVFLDKRIVAARLNGSLDFFSLETHTALSPLQFRGTPGRGSSPASPVYSSSDT
              760       770       780       790       800       810

        1070      1080      1090      1100      1110      1120     
pF1KSD VACHLTHTVPCAHQKPITALKAAAGRLVTGSQDHTLRVFRLEDSCCLFTLQGHSGAITTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VACHLTHTVPCAHQKPITALKAAAGRLVTGSQDHTLRVFRLEDSCCLFTLQGHSGAITTV
              820       830       840       850       860       870

        1130      1140      1150      1160      1170      1180     
pF1KSD YIDQTMVLASGGQDGAICLWDVLTGSRVSHVFAHRGDVTSLTCTTSCVISSGLDDLISIW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YIDQTMVLASGGQDGAICLWDVLTGSRVSHVFAHRGDVTSLTCTTSCVISSGLDDLISIW
              880       890       900       910       920       930

        1190      1200      1210      1220      1230      1240     
pF1KSD DRSTGIKFYSIQQDLGCGASLGVISDNLLVTGGQGCVSFWDLNYGDLLQTVYLGKNSEAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DRSTGIKFYSIQQDLGCGASLGVISDNLLVTGGQGCVSFWDLNYGDLLQTVYLGKNSEAQ
              940       950       960       970       980       990

        1250      1260      1270         
pF1KSD PARQILVLDNAAIVCNFGSELSLVYVPSVLEKLD
       ::::::::::::::::::::::::::::::::::
XP_005 PARQILVLDNAAIVCNFGSELSLVYVPSVLEKLD
             1000      1010      1020    

>>NP_001306973 (OMIM: 601510) sterol regulatory element-  (1023 aa)
 initn: 3869 init1: 3816 opt: 6942  Z-score: 4707.0  bits: 882.8 E(85289):    0
Smith-Waterman score: 6942; 99.9% identity (99.9% similar) in 1024 aa overlap (256-1279:1-1023)

         230       240       250       260       270       280     
pF1KSD YTRKRMVSYTITLVFQHYHAKFLGSLRARLMLLHPSPNCSLRAESLVHVHFKEEIGVAEL
                                     ::::::::::::::::::::::::::::::
NP_001                               MLLHPSPNCSLRAESLVHVHFKEEIGVAEL
                                             10        20        30

         290       300       310       320       330       340     
pF1KSD IPLVTTYIILFAYIYFSTRKIDMVKSKWGLALAAVVTVLSSLLMSVGLCTLFGLTPTLNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IPLVTTYIILFAYIYFSTRKIDMVKSKWGLALAAVVTVLSSLLMSVGLCTLFGLTPTLNG
               40        50        60        70        80        90

         350       360       370       380       390       400     
pF1KSD GEIFPYLVVVIGLENVLVLTKSVVSTPVDLEVKLRIAQGLSSESWSIMKNMATELGIILI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GEIFPYLVVVIGLENVLVLTKSVVSTPVDLEVKLRIAQGLSSESWSIMKNMATELGIILI
              100       110       120       130       140       150

         410       420       430       440       450       460     
pF1KSD GYFTLVPAIQEFCLFAVVGLVSDFFLQMLFFTTVLSIDIRRMELADLNKRLPPEACLPSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GYFTLVPAIQEFCLFAVVGLVSDFFLQMLFFTTVLSIDIRRMELADLNKRLPPEACLPSA
              160       170       180       190       200       210

         470       480       490       500       510       520     
pF1KSD KPVGQPTRYERQLAVRPSTPHTITLQPSSFRNLRLPKRLRVVYFLARTRLAQRLIMAGTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KPVGQPTRYERQLAVRPSTPHTITLQPSSFRNLRLPKRLRVVYFLARTRLAQRLIMAGTV
              220       230       240       250       260       270

         530       540       550       560       570       580     
pF1KSD VWIGILVYTDPAGLRNYLAAQVTEQSPLGEGALAPMPVPSGMLPPSHPDPAFSIFPPDAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VWIGILVYTDPAGLRNYLAAQVTEQSPLGEGALAPMPVPSGMLPPSHPDPAFSIFPPDAP
              280       290       300       310       320       330

         590       600       610       620       630       640     
pF1KSD KLPENQTSPGESPERGGPAEVVHDSPVPEVTWGPEDEELWRKLSFRHWPTLFSYYNITLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLPENQTSPGESPERGGPAEVVHDSPVPEVTWGPEDEELWRKLSFRHWPTLFSYYNITLA
              340       350       360       370       380       390

         650       660       670       680       690       700     
pF1KSD KRYISLLPVIPVTLRLNPREALEGRHPQDGRSAWPPPGPIPAGHWEAGPKGPGGVQAHGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRYISLLPVIPVTLRLNPREALEGRHPQDGRSAWPPPGPIPAGHWEAGPKGPGGVQAHGD
              400       410       420       430       440       450

         710       720       730       740       750       760     
pF1KSD VTLYKVAALGLATGIVLVLLLLCLYRVLCPRNYGQLGGGPGRRRRGELPCDDYGYAPPET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTLYKVAALGLATGIVLVLLLLCLYRVLCPRNYGQLGGGPGRRRRGELPCDDYGYAPPET
              460       470       480       490       500       510

         770       780       790       800       810       820     
pF1KSD EIVPLVLRGHLMDIECLASDGMLLVSCCLAGHVCVWDAQTGDCLTRIPRPGRQRRDSGVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::
NP_001 EIVPLVLRGHLMDIECLASDGMLLVSCCLAGHVCVWDAQTGDCLTRIPRPG-QRRDSGVG
              520       530       540       550       560          

         830       840       850       860       870       880     
pF1KSD SGLEAQESWERLSDGGKAGPEEPGDSPPLRHRPRGPPPPSLFGDQPDLTCLIDTNFSAQP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGLEAQESWERLSDGGKAGPEEPGDSPPLRHRPRGPPPPSLFGDQPDLTCLIDTNFSAQP
     570       580       590       600       610       620         

         890       900       910       920       930       940     
pF1KSD RSSQPTQPEPRHRAVCGRSRDSPGYDFSCLVQRVYQEEGLAAVCTPALRPPSPGPVLSQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSSQPTQPEPRHRAVCGRSRDSPGYDFSCLVQRVYQEEGLAAVCTPALRPPSPGPVLSQA
     630       640       650       660       670       680         

         950       960       970       980       990      1000     
pF1KSD PEDEGGSPEKGSPSLAWAPSAEGSIWSLELQGNLIVVGRSSGRLEVWDAIEGVLCCSSEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PEDEGGSPEKGSPSLAWAPSAEGSIWSLELQGNLIVVGRSSGRLEVWDAIEGVLCCSSEE
     690       700       710       720       730       740         

        1010      1020      1030      1040      1050      1060     
pF1KSD VSSGITALVFLDKRIVAARLNGSLDFFSLETHTALSPLQFRGTPGRGSSPASPVYSSSDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSSGITALVFLDKRIVAARLNGSLDFFSLETHTALSPLQFRGTPGRGSSPASPVYSSSDT
     750       760       770       780       790       800         

        1070      1080      1090      1100      1110      1120     
pF1KSD VACHLTHTVPCAHQKPITALKAAAGRLVTGSQDHTLRVFRLEDSCCLFTLQGHSGAITTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VACHLTHTVPCAHQKPITALKAAAGRLVTGSQDHTLRVFRLEDSCCLFTLQGHSGAITTV
     810       820       830       840       850       860         

        1130      1140      1150      1160      1170      1180     
pF1KSD YIDQTMVLASGGQDGAICLWDVLTGSRVSHVFAHRGDVTSLTCTTSCVISSGLDDLISIW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YIDQTMVLASGGQDGAICLWDVLTGSRVSHVFAHRGDVTSLTCTTSCVISSGLDDLISIW
     870       880       890       900       910       920         

        1190      1200      1210      1220      1230      1240     
pF1KSD DRSTGIKFYSIQQDLGCGASLGVISDNLLVTGGQGCVSFWDLNYGDLLQTVYLGKNSEAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRSTGIKFYSIQQDLGCGASLGVISDNLLVTGGQGCVSFWDLNYGDLLQTVYLGKNSEAQ
     930       940       950       960       970       980         

        1250      1260      1270         
pF1KSD PARQILVLDNAAIVCNFGSELSLVYVPSVLEKLD
       ::::::::::::::::::::::::::::::::::
NP_001 PARQILVLDNAAIVCNFGSELSLVYVPSVLEKLD
     990      1000      1010      1020   

>>XP_011531804 (OMIM: 601510) PREDICTED: sterol regulato  (898 aa)
 initn: 6163 init1: 6163 opt: 6163  Z-score: 4180.7  bits: 785.3 E(85289):    0
Smith-Waterman score: 6163; 100.0% identity (100.0% similar) in 896 aa overlap (384-1279:3-898)

           360       370       380       390       400       410   
pF1KSD VVIGLENVLVLTKSVVSTPVDLEVKLRIAQGLSSESWSIMKNMATELGIILIGYFTLVPA
                                     ::::::::::::::::::::::::::::::
XP_011                             MAGLSSESWSIMKNMATELGIILIGYFTLVPA
                                           10        20        30  

           420       430       440       450       460       470   
pF1KSD IQEFCLFAVVGLVSDFFLQMLFFTTVLSIDIRRMELADLNKRLPPEACLPSAKPVGQPTR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IQEFCLFAVVGLVSDFFLQMLFFTTVLSIDIRRMELADLNKRLPPEACLPSAKPVGQPTR
             40        50        60        70        80        90  

           480       490       500       510       520       530   
pF1KSD YERQLAVRPSTPHTITLQPSSFRNLRLPKRLRVVYFLARTRLAQRLIMAGTVVWIGILVY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YERQLAVRPSTPHTITLQPSSFRNLRLPKRLRVVYFLARTRLAQRLIMAGTVVWIGILVY
            100       110       120       130       140       150  

           540       550       560       570       580       590   
pF1KSD TDPAGLRNYLAAQVTEQSPLGEGALAPMPVPSGMLPPSHPDPAFSIFPPDAPKLPENQTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TDPAGLRNYLAAQVTEQSPLGEGALAPMPVPSGMLPPSHPDPAFSIFPPDAPKLPENQTS
            160       170       180       190       200       210  

           600       610       620       630       640       650   
pF1KSD PGESPERGGPAEVVHDSPVPEVTWGPEDEELWRKLSFRHWPTLFSYYNITLAKRYISLLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGESPERGGPAEVVHDSPVPEVTWGPEDEELWRKLSFRHWPTLFSYYNITLAKRYISLLP
            220       230       240       250       260       270  

           660       670       680       690       700       710   
pF1KSD VIPVTLRLNPREALEGRHPQDGRSAWPPPGPIPAGHWEAGPKGPGGVQAHGDVTLYKVAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VIPVTLRLNPREALEGRHPQDGRSAWPPPGPIPAGHWEAGPKGPGGVQAHGDVTLYKVAA
            280       290       300       310       320       330  

           720       730       740       750       760       770   
pF1KSD LGLATGIVLVLLLLCLYRVLCPRNYGQLGGGPGRRRRGELPCDDYGYAPPETEIVPLVLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGLATGIVLVLLLLCLYRVLCPRNYGQLGGGPGRRRRGELPCDDYGYAPPETEIVPLVLR
            340       350       360       370       380       390  

           780       790       800       810       820       830   
pF1KSD GHLMDIECLASDGMLLVSCCLAGHVCVWDAQTGDCLTRIPRPGRQRRDSGVGSGLEAQES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GHLMDIECLASDGMLLVSCCLAGHVCVWDAQTGDCLTRIPRPGRQRRDSGVGSGLEAQES
            400       410       420       430       440       450  

           840       850       860       870       880       890   
pF1KSD WERLSDGGKAGPEEPGDSPPLRHRPRGPPPPSLFGDQPDLTCLIDTNFSAQPRSSQPTQP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WERLSDGGKAGPEEPGDSPPLRHRPRGPPPPSLFGDQPDLTCLIDTNFSAQPRSSQPTQP
            460       470       480       490       500       510  

           900       910       920       930       940       950   
pF1KSD EPRHRAVCGRSRDSPGYDFSCLVQRVYQEEGLAAVCTPALRPPSPGPVLSQAPEDEGGSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPRHRAVCGRSRDSPGYDFSCLVQRVYQEEGLAAVCTPALRPPSPGPVLSQAPEDEGGSP
            520       530       540       550       560       570  

           960       970       980       990      1000      1010   
pF1KSD EKGSPSLAWAPSAEGSIWSLELQGNLIVVGRSSGRLEVWDAIEGVLCCSSEEVSSGITAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKGSPSLAWAPSAEGSIWSLELQGNLIVVGRSSGRLEVWDAIEGVLCCSSEEVSSGITAL
            580       590       600       610       620       630  

          1020      1030      1040      1050      1060      1070   
pF1KSD VFLDKRIVAARLNGSLDFFSLETHTALSPLQFRGTPGRGSSPASPVYSSSDTVACHLTHT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VFLDKRIVAARLNGSLDFFSLETHTALSPLQFRGTPGRGSSPASPVYSSSDTVACHLTHT
            640       650       660       670       680       690  

          1080      1090      1100      1110      1120      1130   
pF1KSD VPCAHQKPITALKAAAGRLVTGSQDHTLRVFRLEDSCCLFTLQGHSGAITTVYIDQTMVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPCAHQKPITALKAAAGRLVTGSQDHTLRVFRLEDSCCLFTLQGHSGAITTVYIDQTMVL
            700       710       720       730       740       750  

          1140      1150      1160      1170      1180      1190   
pF1KSD ASGGQDGAICLWDVLTGSRVSHVFAHRGDVTSLTCTTSCVISSGLDDLISIWDRSTGIKF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASGGQDGAICLWDVLTGSRVSHVFAHRGDVTSLTCTTSCVISSGLDDLISIWDRSTGIKF
            760       770       780       790       800       810  

          1200      1210      1220      1230      1240      1250   
pF1KSD YSIQQDLGCGASLGVISDNLLVTGGQGCVSFWDLNYGDLLQTVYLGKNSEAQPARQILVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YSIQQDLGCGASLGVISDNLLVTGGQGCVSFWDLNYGDLLQTVYLGKNSEAQPARQILVL
            820       830       840       850       860       870  

          1260      1270         
pF1KSD DNAAIVCNFGSELSLVYVPSVLEKLD
       ::::::::::::::::::::::::::
XP_011 DNAAIVCNFGSELSLVYVPSVLEKLD
            880       890        

>>XP_005265028 (OMIM: 601510) PREDICTED: sterol regulato  (887 aa)
 initn: 6104 init1: 6104 opt: 6104  Z-score: 4140.8  bits: 777.9 E(85289):    0
Smith-Waterman score: 6104; 100.0% identity (100.0% similar) in 887 aa overlap (393-1279:1-887)

            370       380       390       400       410       420  
pF1KSD VLTKSVVSTPVDLEVKLRIAQGLSSESWSIMKNMATELGIILIGYFTLVPAIQEFCLFAV
                                     ::::::::::::::::::::::::::::::
XP_005                               MKNMATELGIILIGYFTLVPAIQEFCLFAV
                                             10        20        30

            430       440       450       460       470       480  
pF1KSD VGLVSDFFLQMLFFTTVLSIDIRRMELADLNKRLPPEACLPSAKPVGQPTRYERQLAVRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VGLVSDFFLQMLFFTTVLSIDIRRMELADLNKRLPPEACLPSAKPVGQPTRYERQLAVRP
               40        50        60        70        80        90

            490       500       510       520       530       540  
pF1KSD STPHTITLQPSSFRNLRLPKRLRVVYFLARTRLAQRLIMAGTVVWIGILVYTDPAGLRNY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 STPHTITLQPSSFRNLRLPKRLRVVYFLARTRLAQRLIMAGTVVWIGILVYTDPAGLRNY
              100       110       120       130       140       150

            550       560       570       580       590       600  
pF1KSD LAAQVTEQSPLGEGALAPMPVPSGMLPPSHPDPAFSIFPPDAPKLPENQTSPGESPERGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LAAQVTEQSPLGEGALAPMPVPSGMLPPSHPDPAFSIFPPDAPKLPENQTSPGESPERGG
              160       170       180       190       200       210

            610       620       630       640       650       660  
pF1KSD PAEVVHDSPVPEVTWGPEDEELWRKLSFRHWPTLFSYYNITLAKRYISLLPVIPVTLRLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PAEVVHDSPVPEVTWGPEDEELWRKLSFRHWPTLFSYYNITLAKRYISLLPVIPVTLRLN
              220       230       240       250       260       270

            670       680       690       700       710       720  
pF1KSD PREALEGRHPQDGRSAWPPPGPIPAGHWEAGPKGPGGVQAHGDVTLYKVAALGLATGIVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PREALEGRHPQDGRSAWPPPGPIPAGHWEAGPKGPGGVQAHGDVTLYKVAALGLATGIVL
              280       290       300       310       320       330

            730       740       750       760       770       780  
pF1KSD VLLLLCLYRVLCPRNYGQLGGGPGRRRRGELPCDDYGYAPPETEIVPLVLRGHLMDIECL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VLLLLCLYRVLCPRNYGQLGGGPGRRRRGELPCDDYGYAPPETEIVPLVLRGHLMDIECL
              340       350       360       370       380       390

            790       800       810       820       830       840  
pF1KSD ASDGMLLVSCCLAGHVCVWDAQTGDCLTRIPRPGRQRRDSGVGSGLEAQESWERLSDGGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ASDGMLLVSCCLAGHVCVWDAQTGDCLTRIPRPGRQRRDSGVGSGLEAQESWERLSDGGK
              400       410       420       430       440       450

            850       860       870       880       890       900  
pF1KSD AGPEEPGDSPPLRHRPRGPPPPSLFGDQPDLTCLIDTNFSAQPRSSQPTQPEPRHRAVCG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AGPEEPGDSPPLRHRPRGPPPPSLFGDQPDLTCLIDTNFSAQPRSSQPTQPEPRHRAVCG
              460       470       480       490       500       510

            910       920       930       940       950       960  
pF1KSD RSRDSPGYDFSCLVQRVYQEEGLAAVCTPALRPPSPGPVLSQAPEDEGGSPEKGSPSLAW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RSRDSPGYDFSCLVQRVYQEEGLAAVCTPALRPPSPGPVLSQAPEDEGGSPEKGSPSLAW
              520       530       540       550       560       570

            970       980       990      1000      1010      1020  
pF1KSD APSAEGSIWSLELQGNLIVVGRSSGRLEVWDAIEGVLCCSSEEVSSGITALVFLDKRIVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 APSAEGSIWSLELQGNLIVVGRSSGRLEVWDAIEGVLCCSSEEVSSGITALVFLDKRIVA
              580       590       600       610       620       630

           1030      1040      1050      1060      1070      1080  
pF1KSD ARLNGSLDFFSLETHTALSPLQFRGTPGRGSSPASPVYSSSDTVACHLTHTVPCAHQKPI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ARLNGSLDFFSLETHTALSPLQFRGTPGRGSSPASPVYSSSDTVACHLTHTVPCAHQKPI
              640       650       660       670       680       690

           1090      1100      1110      1120      1130      1140  
pF1KSD TALKAAAGRLVTGSQDHTLRVFRLEDSCCLFTLQGHSGAITTVYIDQTMVLASGGQDGAI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TALKAAAGRLVTGSQDHTLRVFRLEDSCCLFTLQGHSGAITTVYIDQTMVLASGGQDGAI
              700       710       720       730       740       750

           1150      1160      1170      1180      1190      1200  
pF1KSD CLWDVLTGSRVSHVFAHRGDVTSLTCTTSCVISSGLDDLISIWDRSTGIKFYSIQQDLGC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CLWDVLTGSRVSHVFAHRGDVTSLTCTTSCVISSGLDDLISIWDRSTGIKFYSIQQDLGC
              760       770       780       790       800       810

           1210      1220      1230      1240      1250      1260  
pF1KSD GASLGVISDNLLVTGGQGCVSFWDLNYGDLLQTVYLGKNSEAQPARQILVLDNAAIVCNF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GASLGVISDNLLVTGGQGCVSFWDLNYGDLLQTVYLGKNSEAQPARQILVLDNAAIVCNF
              820       830       840       850       860       870

           1270         
pF1KSD GSELSLVYVPSVLEKLD
       :::::::::::::::::
XP_005 GSELSLVYVPSVLEKLD
              880       




1279 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 00:36:24 2016 done: Thu Nov  3 00:36:26 2016
 Total Scan time: 15.080 Total Display time:  0.470

Function used was FASTA [36.3.4 Apr, 2011]
Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.com