Result of FASTA (omim) for pF1KSDA0161
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KSDA0161, 292 aa
  1>>>pF1KSDA0161 292 - 292 aa - 292 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.4325+/-0.000383; mu= 17.3457+/- 0.024
 mean_var=126.9826+/-26.018, 0's: 0 Z-trim(117.2): 97  B-trim: 1355 in 2/50
 Lambda= 0.113816
 statistics sampled from 28953 (29057) to 28953 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.696), E-opt: 0.2 (0.341), width:  16
 Scan time:  6.030

The best scores are:                                      opt bits E(85289)
NP_001120833 (OMIM: 610872) E3 ubiquitin-protein l ( 587)  450 85.1 3.5e-16
NP_001287755 (OMIM: 610872) E3 ubiquitin-protein l ( 731)  450 85.2   4e-16
XP_011519741 (OMIM: 605624) PREDICTED: E3 ubiquiti ( 465)  389 75.0 3.1e-13
XP_011519740 (OMIM: 605624) PREDICTED: E3 ubiquiti ( 498)  389 75.0 3.2e-13
NP_005735 (OMIM: 605624) E3 ubiquitin-protein liga ( 557)  389 75.1 3.5e-13
XP_016861030 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 409)  380 73.4   8e-13
XP_016861029 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 409)  380 73.4   8e-13
XP_016861026 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 421)  380 73.5 8.1e-13
XP_016861025 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 421)  380 73.5 8.1e-13
XP_016861028 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 421)  380 73.5 8.1e-13
XP_016861027 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 421)  380 73.5 8.1e-13
XP_011531577 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 421)  380 73.5 8.1e-13
XP_016861021 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 493)  380 73.5 8.9e-13
XP_016861020 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 493)  380 73.5 8.9e-13
NP_006312 (OMIM: 605615) E3 ubiquitin-protein liga ( 493)  380 73.5 8.9e-13
NP_001304262 (OMIM: 605615) E3 ubiquitin-protein l ( 493)  380 73.5 8.9e-13
NP_001304263 (OMIM: 605615) E3 ubiquitin-protein l ( 351)  362 70.4 5.6e-12
XP_006710421 (OMIM: 610872) PREDICTED: E3 ubiquiti ( 588)  338 66.7 1.2e-10
XP_006710420 (OMIM: 610872) PREDICTED: E3 ubiquiti ( 688)  338 66.8 1.3e-10
NP_699172 (OMIM: 610872) E3 ubiquitin-protein liga ( 732)  338 66.9 1.4e-10
XP_006710419 (OMIM: 610872) PREDICTED: E3 ubiquiti ( 732)  338 66.9 1.4e-10
XP_011531575 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 432)  334 65.9 1.5e-10
XP_011531572 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 444)  334 65.9 1.6e-10
XP_016861022 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 444)  334 65.9 1.6e-10
XP_016861023 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 444)  334 65.9 1.6e-10
XP_016861024 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 444)  334 65.9 1.6e-10
XP_011531573 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 444)  334 65.9 1.6e-10
XP_011531570 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 516)  334 66.0 1.7e-10
XP_011531569 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 516)  334 66.0 1.7e-10
XP_011531568 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 516)  334 66.0 1.7e-10
XP_011531567 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 516)  334 66.0 1.7e-10
XP_016867854 (OMIM: 212840,609948) PREDICTED: E3 u ( 488)  331 65.5 2.3e-10
XP_011513738 (OMIM: 212840,609948) PREDICTED: E3 u ( 488)  331 65.5 2.3e-10
XP_016867852 (OMIM: 212840,609948) PREDICTED: E3 u ( 866)  331 65.8 3.4e-10
NP_996999 (OMIM: 212840,609948) E3 ubiquitin-prote ( 866)  331 65.8 3.4e-10
XP_005249842 (OMIM: 212840,609948) PREDICTED: E3 u ( 923)  331 65.8 3.5e-10
NP_996994 (OMIM: 212840,609948) E3 ubiquitin-prote ( 923)  331 65.8 3.5e-10
XP_016868793 (OMIM: 607119) PREDICTED: E3 ubiquiti ( 784)  330 65.6 3.5e-10
XP_011515258 (OMIM: 607119) PREDICTED: E3 ubiquiti ( 784)  330 65.6 3.5e-10
XP_005250910 (OMIM: 607119) PREDICTED: E3 ubiquiti ( 838)  330 65.6 3.7e-10
XP_016868792 (OMIM: 607119) PREDICTED: E3 ubiquiti ( 838)  330 65.6 3.7e-10
NP_001267468 (OMIM: 607119) E3 ubiquitin-protein l ( 838)  330 65.6 3.7e-10
XP_016868791 (OMIM: 607119) PREDICTED: E3 ubiquiti ( 838)  330 65.6 3.7e-10
NP_904355 (OMIM: 607119) E3 ubiquitin-protein liga ( 838)  330 65.6 3.7e-10
NP_056250 (OMIM: 607119) E3 ubiquitin-protein liga ( 838)  330 65.6 3.7e-10
XP_011512731 (OMIM: 607489) PREDICTED: cullin-9 is (1834)  311 62.9 5.2e-09
XP_016866079 (OMIM: 607489) PREDICTED: cullin-9 is (1909)  311 63.0 5.3e-09
XP_011512729 (OMIM: 607489) PREDICTED: cullin-9 is (2095)  311 63.0 5.6e-09
XP_011512728 (OMIM: 607489) PREDICTED: cullin-9 is (2339)  311 63.1   6e-09
XP_011512727 (OMIM: 607489) PREDICTED: cullin-9 is (2456)  311 63.1 6.2e-09


>>NP_001120833 (OMIM: 610872) E3 ubiquitin-protein ligas  (587 aa)
 initn: 325 init1: 141 opt: 450  Z-score: 411.6  bits: 85.1 E(85289): 3.5e-16
Smith-Waterman score: 450; 30.4% identity (57.9% similar) in 273 aa overlap (18-273:117-376)

                            10        20        30        40       
pF1KSD              MTTARYRPTWDLALDPLVSCKLCLGEYPVEQMTTIAQCQCIFCTLCL
                                     : : ::: . : :.   . .:    :  ::
NP_001 EAEAEAAAAAAEPGFDDEEAAEGGGPGAEEVECPLCLVRLPPERAPRLLSCPHRSCRDCL
         90       100       110       120       130       140      

        50        60        70        80         90       100      
pF1KSD KQYVELLIKEGLETAISCPDAACPKQGHLQENEIECMVA-AEIMQRYKKLQFEREVLFDP
       ..:..: :.:. .. ::::.  : ..  :. ..:. ..:   .:..:......: .  ::
NP_001 RHYLRLEISES-RVPISCPE--CSER--LNPHDIRLLLADPPLMHKYEEFMLRRYLASDP
        150        160           170       180       190       200 

         110        120       130         140       150            
pF1KSD -CRTWCPASTC-QAVCQLQDVGLQTPQPVQCK--ACRMEFCSTCKASWHPGQGCP-----
        :: ::::  :  ::      :  .   . :.  .:. :::  ::  :::.: :      
NP_001 DCR-WCPAPDCGYAVIAY---GCASCPKLTCEREGCQTEFCYHCKQIWHPNQTCDMARQQ
              210          220       230       240       250       

       160       170        180       190         200       210    
pF1KSD ETMPITFLPGETSA-AFKMEEDDAPIKRCPKCKVYIER--DEGCAQMMCKNCKHAFCWYC
       ... .     .::. .. .:     :: ::.:..:: .  : .: .: :  :   ::: :
NP_001 RAQTLRVRTKHTSGLSYGQESGPDDIKPCPRCSAYIIKMNDGSCNHMTCAVCGCEFCWLC
       260       270       280       290       300       310       

          220        230         240        250       260       270
pF1KSD LESLDDDFLLIHY-DKGPCR--NKLGHSRAS-VIWHRTQVVGIFAGFGLLLLVASPFLLL
       .. ..:    .:: . . :   .:   :: . ..:.   ..:  .:..:.  .: : ...
NP_001 MKEISD----LHYLSPSGCTFWGKKPWSRKKKILWQLGTLIGAPVGISLIAGIAIPAMVI
       320           330       340       350       360       370   

              280       290                                        
pF1KSD ATPFVLCCKCKCSKGDDDPLPT                                      
       . :                                                         
NP_001 GIPVYVGRKIHSRYEGRKTSKHKRNLAITGGVTLSVIASPVIAAVSVGIGVPIMLAYVYG
           380       390       400       410       420       430   

>>NP_001287755 (OMIM: 610872) E3 ubiquitin-protein ligas  (731 aa)
 initn: 325 init1: 141 opt: 450  Z-score: 410.5  bits: 85.2 E(85289): 4e-16
Smith-Waterman score: 450; 30.4% identity (57.9% similar) in 273 aa overlap (18-273:117-376)

                            10        20        30        40       
pF1KSD              MTTARYRPTWDLALDPLVSCKLCLGEYPVEQMTTIAQCQCIFCTLCL
                                     : : ::: . : :.   . .:    :  ::
NP_001 EAEAEAAAAAAEPGFDDEEAAEGGGPGAEEVECPLCLVRLPPERAPRLLSCPHRSCRDCL
         90       100       110       120       130       140      

        50        60        70        80         90       100      
pF1KSD KQYVELLIKEGLETAISCPDAACPKQGHLQENEIECMVA-AEIMQRYKKLQFEREVLFDP
       ..:..: :.:. .. ::::.  : ..  :. ..:. ..:   .:..:......: .  ::
NP_001 RHYLRLEISES-RVPISCPE--CSER--LNPHDIRLLLADPPLMHKYEEFMLRRYLASDP
        150        160           170       180       190       200 

         110        120       130         140       150            
pF1KSD -CRTWCPASTC-QAVCQLQDVGLQTPQPVQCK--ACRMEFCSTCKASWHPGQGCP-----
        :: ::::  :  ::      :  .   . :.  .:. :::  ::  :::.: :      
NP_001 DCR-WCPAPDCGYAVIAY---GCASCPKLTCEREGCQTEFCYHCKQIWHPNQTCDMARQQ
              210          220       230       240       250       

       160       170        180       190         200       210    
pF1KSD ETMPITFLPGETSA-AFKMEEDDAPIKRCPKCKVYIER--DEGCAQMMCKNCKHAFCWYC
       ... .     .::. .. .:     :: ::.:..:: .  : .: .: :  :   ::: :
NP_001 RAQTLRVRTKHTSGLSYGQESGPDDIKPCPRCSAYIIKMNDGSCNHMTCAVCGCEFCWLC
       260       270       280       290       300       310       

          220        230         240        250       260       270
pF1KSD LESLDDDFLLIHY-DKGPCR--NKLGHSRAS-VIWHRTQVVGIFAGFGLLLLVASPFLLL
       .. ..:    .:: . . :   .:   :: . ..:.   ..:  .:..:.  .: : ...
NP_001 MKEISD----LHYLSPSGCTFWGKKPWSRKKKILWQLGTLIGAPVGISLIAGIAIPAMVI
       320           330       340       350       360       370   

              280       290                                        
pF1KSD ATPFVLCCKCKCSKGDDDPLPT                                      
       . :                                                         
NP_001 GIPVYVGRKIHSRYEGRKTSKHKRNLAITGGVTLSVIASPVIAAVSVGIGVPIMLAYVYG
           380       390       400       410       420       430   

>>XP_011519741 (OMIM: 605624) PREDICTED: E3 ubiquitin-pr  (465 aa)
 initn: 303 init1: 116 opt: 389  Z-score: 358.6  bits: 75.0 E(85289): 3.1e-13
Smith-Waterman score: 389; 31.5% identity (55.2% similar) in 203 aa overlap (20-215:94-284)

                          10        20        30        40         
pF1KSD            MTTARYRPTWDLALDPLVSCKLCLGEYPVEQMTTIAQCQCIFCTLCLKQ
                                     :..:  .::   .: . .:   ::  : ..
XP_011 KLFAECHVINPSKKSRTRQMNTRSSAQDMPCQICYLNYPNSYFTGL-ECGHKFCMQCWSE
            70        80        90       100        110       120  

      50         60        70        80         90       100       
pF1KSD YVEL-LIKEGLETAISCPDAACPKQGHLQENEIECMVA-AEIMQRYKKLQFEREVLFDPC
       :.   ...::.  .::::  .:     ...: .  ... ...  .:..:  .  :  .  
XP_011 YLTTKIMEEGMGQTISCPAHGCDIL--VDDNTVMRLITDSKVKLKYQHLITNSFVECNRL
            130       140         150       160       170       180

       110       120       130       140       150          160    
pF1KSD RTWCPASTCQAVCQLQDVGLQTPQPVQCKACRMEFCSTCKASWHPGQGCP---ETMPITF
         ::::  :. : ..:       .::.:: :  .:: .:  .::    :    . .    
XP_011 LKWCPAPDCHHVVKVQ---YPDAKPVRCK-CGRQFCFNCGENWHDPVKCKWLKKWIKKCD
              190          200        210       220       230      

          170       180       190       200         210       220  
pF1KSD LPGETSAAFKMEEDDAPIKRCPKCKVYIERDEGCAQMMCKN--CKHAFCWYCLESLDDDF
         .:::  .      :  :.::::.: ::.: :: .:.:.:  ::  ::: ::       
XP_011 DDSETSNWIA-----ANTKECPKCHVTIEKDGGCNHMVCRNQNCKAEFCWVCLGPWEPHG
        240            250       260       270       280       290 

            230       240       250       260       270       280  
pF1KSD LLIHYDKGPCRNKLGHSRASVIWHRTQVVGIFAGFGLLLLVASPFLLLATPFVLCCKCKC
                                                                   
XP_011 SAWYNCNRYNEDDAKAARDAQERSRAALQRYLFYCNRYMNHMQSLRFEHKLYAQVKQKME
             300       310       320       330       340       350 

>>XP_011519740 (OMIM: 605624) PREDICTED: E3 ubiquitin-pr  (498 aa)
 initn: 303 init1: 116 opt: 389  Z-score: 358.3  bits: 75.0 E(85289): 3.2e-13
Smith-Waterman score: 389; 31.5% identity (55.2% similar) in 203 aa overlap (20-215:127-317)

                          10        20        30        40         
pF1KSD            MTTARYRPTWDLALDPLVSCKLCLGEYPVEQMTTIAQCQCIFCTLCLKQ
                                     :..:  .::   .: . .:   ::  : ..
XP_011 KLFAECHVINPSKKSRTRQMNTRSSAQDMPCQICYLNYPNSYFTGL-ECGHKFCMQCWSE
        100       110       120       130       140        150     

      50         60        70        80         90       100       
pF1KSD YVEL-LIKEGLETAISCPDAACPKQGHLQENEIECMVA-AEIMQRYKKLQFEREVLFDPC
       :.   ...::.  .::::  .:     ...: .  ... ...  .:..:  .  :  .  
XP_011 YLTTKIMEEGMGQTISCPAHGCDIL--VDDNTVMRLITDSKVKLKYQHLITNSFVECNRL
         160       170       180         190       200       210   

       110       120       130       140       150          160    
pF1KSD RTWCPASTCQAVCQLQDVGLQTPQPVQCKACRMEFCSTCKASWHPGQGCP---ETMPITF
         ::::  :. : ..:       .::.:: :  .:: .:  .::    :    . .    
XP_011 LKWCPAPDCHHVVKVQ---YPDAKPVRCK-CGRQFCFNCGENWHDPVKCKWLKKWIKKCD
           220          230        240       250       260         

          170       180       190       200         210       220  
pF1KSD LPGETSAAFKMEEDDAPIKRCPKCKVYIERDEGCAQMMCKN--CKHAFCWYCLESLDDDF
         .:::  .      :  :.::::.: ::.: :: .:.:.:  ::  ::: ::       
XP_011 DDSETSNWIA-----ANTKECPKCHVTIEKDGGCNHMVCRNQNCKAEFCWVCLGPWEPHG
     270            280       290       300       310       320    

            230       240       250       260       270       280  
pF1KSD LLIHYDKGPCRNKLGHSRASVIWHRTQVVGIFAGFGLLLLVASPFLLLATPFVLCCKCKC
                                                                   
XP_011 SAWYNCNRYNEDDAKAARDAQERSRAALQRYLFYCNRYMNHMQSLRFEHKLYAQVKQKME
          330       340       350       360       370       380    

>>NP_005735 (OMIM: 605624) E3 ubiquitin-protein ligase A  (557 aa)
 initn: 303 init1: 116 opt: 389  Z-score: 357.7  bits: 75.1 E(85289): 3.5e-13
Smith-Waterman score: 389; 31.5% identity (55.2% similar) in 203 aa overlap (20-215:186-376)

                          10        20        30        40         
pF1KSD            MTTARYRPTWDLALDPLVSCKLCLGEYPVEQMTTIAQCQCIFCTLCLKQ
                                     :..:  .::   .: . .:   ::  : ..
NP_005 KLFAECHVINPSKKSRTRQMNTRSSAQDMPCQICYLNYPNSYFTGL-ECGHKFCMQCWSE
         160       170       180       190       200        210    

      50         60        70        80         90       100       
pF1KSD YVEL-LIKEGLETAISCPDAACPKQGHLQENEIECMVA-AEIMQRYKKLQFEREVLFDPC
       :.   ...::.  .::::  .:     ...: .  ... ...  .:..:  .  :  .  
NP_005 YLTTKIMEEGMGQTISCPAHGCDIL--VDDNTVMRLITDSKVKLKYQHLITNSFVECNRL
          220       230         240       250       260       270  

       110       120       130       140       150          160    
pF1KSD RTWCPASTCQAVCQLQDVGLQTPQPVQCKACRMEFCSTCKASWHPGQGCP---ETMPITF
         ::::  :. : ..:       .::.:: :  .:: .:  .::    :    . .    
NP_005 LKWCPAPDCHHVVKVQ---YPDAKPVRCK-CGRQFCFNCGENWHDPVKCKWLKKWIKKCD
            280          290        300       310       320        

          170       180       190       200         210       220  
pF1KSD LPGETSAAFKMEEDDAPIKRCPKCKVYIERDEGCAQMMCKN--CKHAFCWYCLESLDDDF
         .:::  .      :  :.::::.: ::.: :: .:.:.:  ::  ::: ::       
NP_005 DDSETSNWIA-----ANTKECPKCHVTIEKDGGCNHMVCRNQNCKAEFCWVCLGPWEPHG
      330            340       350       360       370       380   

            230       240       250       260       270       280  
pF1KSD LLIHYDKGPCRNKLGHSRASVIWHRTQVVGIFAGFGLLLLVASPFLLLATPFVLCCKCKC
                                                                   
NP_005 SAWYNCNRYNEDDAKAARDAQERSRAALQRYLFYCNRYMNHMQSLRFEHKLYAQVKQKME
           390       400       410       420       430       440   

>>XP_016861030 (OMIM: 605615) PREDICTED: E3 ubiquitin-pr  (409 aa)
 initn: 339 init1: 184 opt: 380  Z-score: 351.2  bits: 73.4 E(85289): 8e-13
Smith-Waterman score: 380; 29.2% identity (54.0% similar) in 202 aa overlap (16-215:51-243)

                              10        20        30        40     
pF1KSD                MTTARYRPTWDLALDPLVSCKLCLGEYPVEQMTTIAQCQCIFCTL
                                     :   : .:.     :.. ..: ::  ::  
XP_016 ILDRYKSNSAQLLVEARVQPNPSKHVPTSHPPHHCAVCMQFVRKENLLSLA-CQHQFCRS
               30        40        50        60        70          

          50        60        70        80         90       100    
pF1KSD CLKQYVELLIKEGLETAISCPDAACPKQGHLQENEIECMVAAE-IMQRYKKLQFEREVLF
       : .:.  .:.:.:. ...::    :: .    :. .  ..  : . ..:..  :.  :  
XP_016 CWEQHCSVLVKDGVGVGVSCMAQDCPLR--TPEDFVFPLLPNEELREKYRRYLFRDYVES
      80        90       100         110       120       130       

          110       120       130       140       150       160    
pF1KSD DPCRTWCPASTCQAVCQLQDVGLQTPQPVQCKACRMEFCSTCKASWHPGQGCPETMP-IT
             ::.. :  : ..:.      . :::. :   ::  :.  .:    :      .:
XP_016 HYQLQLCPGADCPMVIRVQE---PRARRVQCNRCNEVFCFKCRQMYHAPTDCATIRKWLT
       140       150          160       170       180       190    

           170       180       190       200       210       220   
pF1KSD FLPGETSAAFKMEEDDAPIKRCPKCKVYIERDEGCAQMMCKNCKHAFCWYCLESLDDDFL
           .. .:  .   .:  : ::::.. ::.. :: .:.:..::: :::.::        
XP_016 KCADDSETANYI---SAHTKDCPKCNICIEKNGGCNHMQCSKCKHDFCWMCLGDWKTHGS
          200          210       220       230       240       250 

           230       240       250       260       270       280   
pF1KSD LIHYDKGPCRNKLGHSRASVIWHRTQVVGIFAGFGLLLLVASPFLLLATPFVLCCKCKCS
                                                                   
XP_016 EYYECSRYKENPDIVNQSQQAQAREALKKYLFYFERWENHNKSLQLEAQTYQRIHEKIQE
             260       270       280       290       300       310 

>>XP_016861029 (OMIM: 605615) PREDICTED: E3 ubiquitin-pr  (409 aa)
 initn: 339 init1: 184 opt: 380  Z-score: 351.2  bits: 73.4 E(85289): 8e-13
Smith-Waterman score: 380; 29.2% identity (54.0% similar) in 202 aa overlap (16-215:51-243)

                              10        20        30        40     
pF1KSD                MTTARYRPTWDLALDPLVSCKLCLGEYPVEQMTTIAQCQCIFCTL
                                     :   : .:.     :.. ..: ::  ::  
XP_016 ILDRYKSNSAQLLVEARVQPNPSKHVPTSHPPHHCAVCMQFVRKENLLSLA-CQHQFCRS
               30        40        50        60        70          

          50        60        70        80         90       100    
pF1KSD CLKQYVELLIKEGLETAISCPDAACPKQGHLQENEIECMVAAE-IMQRYKKLQFEREVLF
       : .:.  .:.:.:. ...::    :: .    :. .  ..  : . ..:..  :.  :  
XP_016 CWEQHCSVLVKDGVGVGVSCMAQDCPLR--TPEDFVFPLLPNEELREKYRRYLFRDYVES
      80        90       100         110       120       130       

          110       120       130       140       150       160    
pF1KSD DPCRTWCPASTCQAVCQLQDVGLQTPQPVQCKACRMEFCSTCKASWHPGQGCPETMP-IT
             ::.. :  : ..:.      . :::. :   ::  :.  .:    :      .:
XP_016 HYQLQLCPGADCPMVIRVQE---PRARRVQCNRCNEVFCFKCRQMYHAPTDCATIRKWLT
       140       150          160       170       180       190    

           170       180       190       200       210       220   
pF1KSD FLPGETSAAFKMEEDDAPIKRCPKCKVYIERDEGCAQMMCKNCKHAFCWYCLESLDDDFL
           .. .:  .   .:  : ::::.. ::.. :: .:.:..::: :::.::        
XP_016 KCADDSETANYI---SAHTKDCPKCNICIEKNGGCNHMQCSKCKHDFCWMCLGDWKTHGS
          200          210       220       230       240       250 

           230       240       250       260       270       280   
pF1KSD LIHYDKGPCRNKLGHSRASVIWHRTQVVGIFAGFGLLLLVASPFLLLATPFVLCCKCKCS
                                                                   
XP_016 EYYECSRYKENPDIVNQSQQAQAREALKKYLFYFERWENHNKSLQLEAQTYQRIHEKIQE
             260       270       280       290       300       310 

>>XP_016861026 (OMIM: 605615) PREDICTED: E3 ubiquitin-pr  (421 aa)
 initn: 339 init1: 184 opt: 380  Z-score: 351.1  bits: 73.5 E(85289): 8.1e-13
Smith-Waterman score: 380; 29.2% identity (54.0% similar) in 202 aa overlap (16-215:63-255)

                              10        20        30        40     
pF1KSD                MTTARYRPTWDLALDPLVSCKLCLGEYPVEQMTTIAQCQCIFCTL
                                     :   : .:.     :.. ..: ::  ::  
XP_016 ILDRYKSNSAQLLVEARVQPNPSKHVPTSHPPHHCAVCMQFVRKENLLSLA-CQHQFCRS
             40        50        60        70        80         90 

          50        60        70        80         90       100    
pF1KSD CLKQYVELLIKEGLETAISCPDAACPKQGHLQENEIECMVAAE-IMQRYKKLQFEREVLF
       : .:.  .:.:.:. ...::    :: .    :. .  ..  : . ..:..  :.  :  
XP_016 CWEQHCSVLVKDGVGVGVSCMAQDCPLR--TPEDFVFPLLPNEELREKYRRYLFRDYVES
             100       110         120       130       140         

          110       120       130       140       150       160    
pF1KSD DPCRTWCPASTCQAVCQLQDVGLQTPQPVQCKACRMEFCSTCKASWHPGQGCPETMP-IT
             ::.. :  : ..:.      . :::. :   ::  :.  .:    :      .:
XP_016 HYQLQLCPGADCPMVIRVQE---PRARRVQCNRCNEVFCFKCRQMYHAPTDCATIRKWLT
     150       160          170       180       190       200      

           170       180       190       200       210       220   
pF1KSD FLPGETSAAFKMEEDDAPIKRCPKCKVYIERDEGCAQMMCKNCKHAFCWYCLESLDDDFL
           .. .:  .   .:  : ::::.. ::.. :: .:.:..::: :::.::        
XP_016 KCADDSETANYI---SAHTKDCPKCNICIEKNGGCNHMQCSKCKHDFCWMCLGDWKTHGS
        210          220       230       240       250       260   

           230       240       250       260       270       280   
pF1KSD LIHYDKGPCRNKLGHSRASVIWHRTQVVGIFAGFGLLLLVASPFLLLATPFVLCCKCKCS
                                                                   
XP_016 EYYECSRYKENPDIVNQSQQAQAREALKKYLFYFERWENHNKSLQLEAQTYQRIHEKIQE
           270       280       290       300       310       320   

>>XP_016861025 (OMIM: 605615) PREDICTED: E3 ubiquitin-pr  (421 aa)
 initn: 339 init1: 184 opt: 380  Z-score: 351.1  bits: 73.5 E(85289): 8.1e-13
Smith-Waterman score: 380; 29.2% identity (54.0% similar) in 202 aa overlap (16-215:63-255)

                              10        20        30        40     
pF1KSD                MTTARYRPTWDLALDPLVSCKLCLGEYPVEQMTTIAQCQCIFCTL
                                     :   : .:.     :.. ..: ::  ::  
XP_016 ILDRYKSNSAQLLVEARVQPNPSKHVPTSHPPHHCAVCMQFVRKENLLSLA-CQHQFCRS
             40        50        60        70        80         90 

          50        60        70        80         90       100    
pF1KSD CLKQYVELLIKEGLETAISCPDAACPKQGHLQENEIECMVAAE-IMQRYKKLQFEREVLF
       : .:.  .:.:.:. ...::    :: .    :. .  ..  : . ..:..  :.  :  
XP_016 CWEQHCSVLVKDGVGVGVSCMAQDCPLR--TPEDFVFPLLPNEELREKYRRYLFRDYVES
             100       110         120       130       140         

          110       120       130       140       150       160    
pF1KSD DPCRTWCPASTCQAVCQLQDVGLQTPQPVQCKACRMEFCSTCKASWHPGQGCPETMP-IT
             ::.. :  : ..:.      . :::. :   ::  :.  .:    :      .:
XP_016 HYQLQLCPGADCPMVIRVQE---PRARRVQCNRCNEVFCFKCRQMYHAPTDCATIRKWLT
     150       160          170       180       190       200      

           170       180       190       200       210       220   
pF1KSD FLPGETSAAFKMEEDDAPIKRCPKCKVYIERDEGCAQMMCKNCKHAFCWYCLESLDDDFL
           .. .:  .   .:  : ::::.. ::.. :: .:.:..::: :::.::        
XP_016 KCADDSETANYI---SAHTKDCPKCNICIEKNGGCNHMQCSKCKHDFCWMCLGDWKTHGS
        210          220       230       240       250       260   

           230       240       250       260       270       280   
pF1KSD LIHYDKGPCRNKLGHSRASVIWHRTQVVGIFAGFGLLLLVASPFLLLATPFVLCCKCKCS
                                                                   
XP_016 EYYECSRYKENPDIVNQSQQAQAREALKKYLFYFERWENHNKSLQLEAQTYQRIHEKIQE
           270       280       290       300       310       320   

>>XP_016861028 (OMIM: 605615) PREDICTED: E3 ubiquitin-pr  (421 aa)
 initn: 339 init1: 184 opt: 380  Z-score: 351.1  bits: 73.5 E(85289): 8.1e-13
Smith-Waterman score: 380; 29.2% identity (54.0% similar) in 202 aa overlap (16-215:63-255)

                              10        20        30        40     
pF1KSD                MTTARYRPTWDLALDPLVSCKLCLGEYPVEQMTTIAQCQCIFCTL
                                     :   : .:.     :.. ..: ::  ::  
XP_016 ILDRYKSNSAQLLVEARVQPNPSKHVPTSHPPHHCAVCMQFVRKENLLSLA-CQHQFCRS
             40        50        60        70        80         90 

          50        60        70        80         90       100    
pF1KSD CLKQYVELLIKEGLETAISCPDAACPKQGHLQENEIECMVAAE-IMQRYKKLQFEREVLF
       : .:.  .:.:.:. ...::    :: .    :. .  ..  : . ..:..  :.  :  
XP_016 CWEQHCSVLVKDGVGVGVSCMAQDCPLR--TPEDFVFPLLPNEELREKYRRYLFRDYVES
             100       110         120       130       140         

          110       120       130       140       150       160    
pF1KSD DPCRTWCPASTCQAVCQLQDVGLQTPQPVQCKACRMEFCSTCKASWHPGQGCPETMP-IT
             ::.. :  : ..:.      . :::. :   ::  :.  .:    :      .:
XP_016 HYQLQLCPGADCPMVIRVQE---PRARRVQCNRCNEVFCFKCRQMYHAPTDCATIRKWLT
     150       160          170       180       190       200      

           170       180       190       200       210       220   
pF1KSD FLPGETSAAFKMEEDDAPIKRCPKCKVYIERDEGCAQMMCKNCKHAFCWYCLESLDDDFL
           .. .:  .   .:  : ::::.. ::.. :: .:.:..::: :::.::        
XP_016 KCADDSETANYI---SAHTKDCPKCNICIEKNGGCNHMQCSKCKHDFCWMCLGDWKTHGS
        210          220       230       240       250       260   

           230       240       250       260       270       280   
pF1KSD LIHYDKGPCRNKLGHSRASVIWHRTQVVGIFAGFGLLLLVASPFLLLATPFVLCCKCKCS
                                                                   
XP_016 EYYECSRYKENPDIVNQSQQAQAREALKKYLFYFERWENHNKSLQLEAQTYQRIHEKIQE
           270       280       290       300       310       320   




292 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 00:21:24 2016 done: Thu Nov  3 00:21:25 2016
 Total Scan time:  6.030 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]
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