Result of FASTA (omim) for pF1KSDA0137
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KSDA0137, 766 aa
  1>>>pF1KSDA0137 766 - 766 aa - 766 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 10.1232+/-0.000496; mu= 1.5384+/- 0.031
 mean_var=652.2119+/-147.670, 0's: 0 Z-trim(120.0): 416  B-trim: 0 in 0/60
 Lambda= 0.050220
 statistics sampled from 34112 (34737) to 34112 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.735), E-opt: 0.2 (0.407), width:  16
 Scan time:  9.000

The best scores are:                                      opt bits E(85289)
NP_036422 (OMIM: 608438) serine/threonine-protein  ( 766) 5105 386.2 2.8e-106
NP_001130026 (OMIM: 608438) serine/threonine-prote ( 718) 4784 362.9 2.7e-99
NP_001130027 (OMIM: 608438) serine/threonine-prote ( 670) 4392 334.4 9.3e-91
XP_016860910 (OMIM: 608438) PREDICTED: serine/thre ( 549) 3674 282.3 3.8e-75
XP_016860911 (OMIM: 608438) PREDICTED: serine/thre ( 549) 3674 282.3 3.8e-75
XP_011522522 (OMIM: 608439) PREDICTED: serine/thre ( 709) 2586 203.6 2.4e-51
XP_011510540 (OMIM: 608438) PREDICTED: serine/thre ( 703) 2558 201.6 9.5e-51
XP_011522525 (OMIM: 608439) PREDICTED: serine/thre ( 709) 2489 196.6 3.1e-49
XP_016879534 (OMIM: 608439) PREDICTED: serine/thre ( 764) 2438 192.9 4.1e-48
XP_011522520 (OMIM: 608439) PREDICTED: serine/thre ( 719) 2427 192.1   7e-48
XP_016879540 (OMIM: 608439) PREDICTED: serine/thre ( 718) 2411 190.9 1.6e-47
XP_016879541 (OMIM: 608439) PREDICTED: serine/thre ( 718) 2411 190.9 1.6e-47
XP_016879542 (OMIM: 608439) PREDICTED: serine/thre ( 718) 2411 190.9 1.6e-47
NP_001271292 (OMIM: 608439) serine/threonine-prote ( 718) 2411 190.9 1.6e-47
XP_016879543 (OMIM: 608439) PREDICTED: serine/thre ( 687) 2309 183.5 2.5e-45
XP_011522531 (OMIM: 608439) PREDICTED: serine/thre ( 623) 2298 182.7 4.2e-45
XP_011522527 (OMIM: 608439) PREDICTED: serine/thre ( 668) 2298 182.7 4.4e-45
XP_011522526 (OMIM: 608439) PREDICTED: serine/thre ( 668) 2298 182.7 4.4e-45
XP_011522529 (OMIM: 608439) PREDICTED: serine/thre ( 668) 2298 182.7 4.4e-45
XP_011522528 (OMIM: 608439) PREDICTED: serine/thre ( 668) 2298 182.7 4.4e-45
XP_011522530 (OMIM: 608439) PREDICTED: serine/thre ( 668) 2298 182.7 4.4e-45
XP_011522523 (OMIM: 608439) PREDICTED: serine/thre ( 740) 2298 182.8 4.6e-45
XP_016879537 (OMIM: 608439) PREDICTED: serine/thre ( 740) 2298 182.8 4.6e-45
XP_016879538 (OMIM: 608439) PREDICTED: serine/thre ( 740) 2298 182.8 4.6e-45
XP_011522518 (OMIM: 608439) PREDICTED: serine/thre ( 772) 2298 182.8 4.7e-45
XP_011522524 (OMIM: 608439) PREDICTED: serine/thre ( 772) 2298 182.8 4.7e-45
XP_011522519 (OMIM: 608439) PREDICTED: serine/thre ( 772) 2298 182.8 4.7e-45
NP_001271262 (OMIM: 608439) serine/threonine-prote ( 772) 2298 182.8 4.7e-45
XP_011522517 (OMIM: 608439) PREDICTED: serine/thre ( 741) 2296 182.6 5.1e-45
XP_016879539 (OMIM: 608439) PREDICTED: serine/thre ( 733) 2293 182.4 5.9e-45
XP_016879548 (OMIM: 608439) PREDICTED: serine/thre ( 601) 2287 181.8 7.2e-45
NP_001317347 (OMIM: 608439) serine/threonine-prote ( 601) 2287 181.8 7.2e-45
XP_016879545 (OMIM: 608439) PREDICTED: serine/thre ( 646) 2287 181.9 7.4e-45
XP_016879546 (OMIM: 608439) PREDICTED: serine/thre ( 646) 2287 181.9 7.4e-45
XP_016879549 (OMIM: 608439) PREDICTED: serine/thre ( 538) 2285 181.6 7.5e-45
XP_016879533 (OMIM: 608439) PREDICTED: serine/thre ( 750) 2287 182.0   8e-45
XP_016879535 (OMIM: 608439) PREDICTED: serine/thre ( 750) 2287 182.0   8e-45
NP_006843 (OMIM: 608439) serine/threonine-protein  ( 750) 2287 182.0   8e-45
XP_016879536 (OMIM: 608439) PREDICTED: serine/thre ( 750) 2287 182.0   8e-45
XP_016879544 (OMIM: 608439) PREDICTED: serine/thre ( 655) 2285 181.8 8.3e-45
XP_011522533 (OMIM: 608439) PREDICTED: serine/thre ( 517)  916 82.4 5.3e-15
NP_009125 (OMIM: 114480,176807,259500,604373,60926 ( 543)  360 42.1  0.0073
XP_011537101 (OMIM: 603168) PREDICTED: serine/thre (1044)  366 43.0  0.0075
NP_003556 (OMIM: 603168) serine/threonine-protein  (1050)  366 43.0  0.0075
XP_016884049 (OMIM: 114480,176807,259500,604373,60 ( 584)  360 42.2  0.0076
NP_001005735 (OMIM: 114480,176807,259500,604373,60 ( 586)  360 42.2  0.0076
XP_011537100 (OMIM: 603168) PREDICTED: serine/thre (1073)  366 43.1  0.0076
XP_011528141 (OMIM: 114480,176807,259500,604373,60 ( 596)  360 42.2  0.0076


>>NP_036422 (OMIM: 608438) serine/threonine-protein kina  (766 aa)
 initn: 5105 init1: 5105 opt: 5105  Z-score: 2029.0  bits: 386.2 E(85289): 2.8e-106
Smith-Waterman score: 5105; 100.0% identity (100.0% similar) in 766 aa overlap (1-766:1-766)

               10        20        30        40        50        60
pF1KSD MSVQSSSGSLEGPPSWSQLSTSPTPGSAAAARSLLNHTPPSGRPREGAMDELHSLDPRRQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MSVQSSSGSLEGPPSWSQLSTSPTPGSAAAARSLLNHTPPSGRPREGAMDELHSLDPRRQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD ELLEARFTGVASGSTGSTGSCSVGAKASTNNESSNHSFGSLGSLSDKESETPEKKQSESS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 ELLEARFTGVASGSTGSTGSCSVGAKASTNNESSNHSFGSLGSLSDKESETPEKKQSESS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD RGRKRKAENQNESSQGKSIGGRGHKISDYFEYQGGNGSSPVRGIPPAIRSPQNSHSHSTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 RGRKRKAENQNESSQGKSIGGRGHKISDYFEYQGGNGSSPVRGIPPAIRSPQNSHSHSTP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD SSSVRPNSPSPTALAFGDHPIVQPKQLSFKIIQTDLTMLKLAALESNKIQDLEKKEGRID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 SSSVRPNSPSPTALAFGDHPIVQPKQLSFKIIQTDLTMLKLAALESNKIQDLEKKEGRID
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD DLLRANCDLRRQIDEQQKLLEKYKERLNKCISMSKKLLIEKSTQEKLSSREKSMQDRLRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 DLLRANCDLRRQIDEQQKLLEKYKERLNKCISMSKKLLIEKSTQEKLSSREKSMQDRLRL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD GHFTTVRHGASFTEQWTDGFAFQNLVKQQEWVNQQREDIERQRKLLAKRKPPTANNSQAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 GHFTTVRHGASFTEQWTDGFAFQNLVKQQEWVNQQREDIERQRKLLAKRKPPTANNSQAP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD STNSEPKQRKNKAVNGAENDPFVRPNLPQLLTLAEYHEQEEIFKLRLGHLKKEEAEIQAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 STNSEPKQRKNKAVNGAENDPFVRPNLPQLLTLAEYHEQEEIFKLRLGHLKKEEAEIQAE
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD LERLERVRNLHIRELKRINNEDNSQFKDHPTLNERYLLLHLLGRGGFSEVYKAFDLYEQR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 LERLERVRNLHIRELKRINNEDNSQFKDHPTLNERYLLLHLLGRGGFSEVYKAFDLYEQR
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD YAAVKIHQLNKSWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDTFCTVLEY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 YAAVKIHQLNKSWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDTFCTVLEY
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD CEGNDLDFYLKQHKLMSEKEARSIVMQIVNALRYLNEIKPPIIHYDLKPGNILLVDGTAC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 CEGNDLDFYLKQHKLMSEKEARSIVMQIVNALRYLNEIKPPIIHYDLKPGNILLVDGTAC
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD GEIKITDFGLSKIMDDDSYGVDGMDLTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 GEIKITDFGLSKIMDDDSYGVDGMDLTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSV
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD GVIFFQCLYGRKPFGHNQSQQDILQENTILKATEVQFPVKPVVSSEAKAFIRRCLAYRKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 GVIFFQCLYGRKPFGHNQSQQDILQENTILKATEVQFPVKPVVSSEAKAFIRRCLAYRKE
              670       680       690       700       710       720

              730       740       750       760      
pF1KSD DRFDVHQLANDPYLLPHMRRSNSSGNLHMAGLTASPTPPSSSIITY
       ::::::::::::::::::::::::::::::::::::::::::::::
NP_036 DRFDVHQLANDPYLLPHMRRSNSSGNLHMAGLTASPTPPSSSIITY
              730       740       750       760      

>>NP_001130026 (OMIM: 608438) serine/threonine-protein k  (718 aa)
 initn: 4784 init1: 4784 opt: 4784  Z-score: 1903.6  bits: 362.9 E(85289): 2.7e-99
Smith-Waterman score: 4784; 100.0% identity (100.0% similar) in 718 aa overlap (49-766:1-718)

       20        30        40        50        60        70        
pF1KSD LSTSPTPGSAAAARSLLNHTPPSGRPREGAMDELHSLDPRRQELLEARFTGVASGSTGST
                                     ::::::::::::::::::::::::::::::
NP_001                               MDELHSLDPRRQELLEARFTGVASGSTGST
                                             10        20        30

       80        90       100       110       120       130        
pF1KSD GSCSVGAKASTNNESSNHSFGSLGSLSDKESETPEKKQSESSRGRKRKAENQNESSQGKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSCSVGAKASTNNESSNHSFGSLGSLSDKESETPEKKQSESSRGRKRKAENQNESSQGKS
               40        50        60        70        80        90

      140       150       160       170       180       190        
pF1KSD IGGRGHKISDYFEYQGGNGSSPVRGIPPAIRSPQNSHSHSTPSSSVRPNSPSPTALAFGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IGGRGHKISDYFEYQGGNGSSPVRGIPPAIRSPQNSHSHSTPSSSVRPNSPSPTALAFGD
              100       110       120       130       140       150

      200       210       220       230       240       250        
pF1KSD HPIVQPKQLSFKIIQTDLTMLKLAALESNKIQDLEKKEGRIDDLLRANCDLRRQIDEQQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HPIVQPKQLSFKIIQTDLTMLKLAALESNKIQDLEKKEGRIDDLLRANCDLRRQIDEQQK
              160       170       180       190       200       210

      260       270       280       290       300       310        
pF1KSD LLEKYKERLNKCISMSKKLLIEKSTQEKLSSREKSMQDRLRLGHFTTVRHGASFTEQWTD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLEKYKERLNKCISMSKKLLIEKSTQEKLSSREKSMQDRLRLGHFTTVRHGASFTEQWTD
              220       230       240       250       260       270

      320       330       340       350       360       370        
pF1KSD GFAFQNLVKQQEWVNQQREDIERQRKLLAKRKPPTANNSQAPSTNSEPKQRKNKAVNGAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GFAFQNLVKQQEWVNQQREDIERQRKLLAKRKPPTANNSQAPSTNSEPKQRKNKAVNGAE
              280       290       300       310       320       330

      380       390       400       410       420       430        
pF1KSD NDPFVRPNLPQLLTLAEYHEQEEIFKLRLGHLKKEEAEIQAELERLERVRNLHIRELKRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NDPFVRPNLPQLLTLAEYHEQEEIFKLRLGHLKKEEAEIQAELERLERVRNLHIRELKRI
              340       350       360       370       380       390

      440       450       460       470       480       490        
pF1KSD NNEDNSQFKDHPTLNERYLLLHLLGRGGFSEVYKAFDLYEQRYAAVKIHQLNKSWRDEKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NNEDNSQFKDHPTLNERYLLLHLLGRGGFSEVYKAFDLYEQRYAAVKIHQLNKSWRDEKK
              400       410       420       430       440       450

      500       510       520       530       540       550        
pF1KSD ENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDTFCTVLEYCEGNDLDFYLKQHKLMSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDTFCTVLEYCEGNDLDFYLKQHKLMSE
              460       470       480       490       500       510

      560       570       580       590       600       610        
pF1KSD KEARSIVMQIVNALRYLNEIKPPIIHYDLKPGNILLVDGTACGEIKITDFGLSKIMDDDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KEARSIVMQIVNALRYLNEIKPPIIHYDLKPGNILLVDGTACGEIKITDFGLSKIMDDDS
              520       530       540       550       560       570

      620       630       640       650       660       670        
pF1KSD YGVDGMDLTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFFQCLYGRKPFGHNQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YGVDGMDLTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFFQCLYGRKPFGHNQ
              580       590       600       610       620       630

      680       690       700       710       720       730        
pF1KSD SQQDILQENTILKATEVQFPVKPVVSSEAKAFIRRCLAYRKEDRFDVHQLANDPYLLPHM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQQDILQENTILKATEVQFPVKPVVSSEAKAFIRRCLAYRKEDRFDVHQLANDPYLLPHM
              640       650       660       670       680       690

      740       750       760      
pF1KSD RRSNSSGNLHMAGLTASPTPPSSSIITY
       ::::::::::::::::::::::::::::
NP_001 RRSNSSGNLHMAGLTASPTPPSSSIITY
              700       710        

>>NP_001130027 (OMIM: 608438) serine/threonine-protein k  (670 aa)
 initn: 4392 init1: 4392 opt: 4392  Z-score: 1750.4  bits: 334.4 E(85289): 9.3e-91
Smith-Waterman score: 4392; 99.8% identity (100.0% similar) in 657 aa overlap (110-766:14-670)

      80        90       100       110       120       130         
pF1KSD SCSVGAKASTNNESSNHSFGSLGSLSDKESETPEKKQSESSRGRKRKAENQNESSQGKSI
                                     .:::::::::::::::::::::::::::::
NP_001                  MAVLFLYDLKTTGKTPEKKQSESSRGRKRKAENQNESSQGKSI
                                10        20        30        40   

     140       150       160       170       180       190         
pF1KSD GGRGHKISDYFEYQGGNGSSPVRGIPPAIRSPQNSHSHSTPSSSVRPNSPSPTALAFGDH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGRGHKISDYFEYQGGNGSSPVRGIPPAIRSPQNSHSHSTPSSSVRPNSPSPTALAFGDH
            50        60        70        80        90       100   

     200       210       220       230       240       250         
pF1KSD PIVQPKQLSFKIIQTDLTMLKLAALESNKIQDLEKKEGRIDDLLRANCDLRRQIDEQQKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PIVQPKQLSFKIIQTDLTMLKLAALESNKIQDLEKKEGRIDDLLRANCDLRRQIDEQQKL
           110       120       130       140       150       160   

     260       270       280       290       300       310         
pF1KSD LEKYKERLNKCISMSKKLLIEKSTQEKLSSREKSMQDRLRLGHFTTVRHGASFTEQWTDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEKYKERLNKCISMSKKLLIEKSTQEKLSSREKSMQDRLRLGHFTTVRHGASFTEQWTDG
           170       180       190       200       210       220   

     320       330       340       350       360       370         
pF1KSD FAFQNLVKQQEWVNQQREDIERQRKLLAKRKPPTANNSQAPSTNSEPKQRKNKAVNGAEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FAFQNLVKQQEWVNQQREDIERQRKLLAKRKPPTANNSQAPSTNSEPKQRKNKAVNGAEN
           230       240       250       260       270       280   

     380       390       400       410       420       430         
pF1KSD DPFVRPNLPQLLTLAEYHEQEEIFKLRLGHLKKEEAEIQAELERLERVRNLHIRELKRIN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DPFVRPNLPQLLTLAEYHEQEEIFKLRLGHLKKEEAEIQAELERLERVRNLHIRELKRIN
           290       300       310       320       330       340   

     440       450       460       470       480       490         
pF1KSD NEDNSQFKDHPTLNERYLLLHLLGRGGFSEVYKAFDLYEQRYAAVKIHQLNKSWRDEKKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NEDNSQFKDHPTLNERYLLLHLLGRGGFSEVYKAFDLYEQRYAAVKIHQLNKSWRDEKKE
           350       360       370       380       390       400   

     500       510       520       530       540       550         
pF1KSD NYHKHACREYRIHKELDHPRIVKLYDYFSLDTDTFCTVLEYCEGNDLDFYLKQHKLMSEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NYHKHACREYRIHKELDHPRIVKLYDYFSLDTDTFCTVLEYCEGNDLDFYLKQHKLMSEK
           410       420       430       440       450       460   

     560       570       580       590       600       610         
pF1KSD EARSIVMQIVNALRYLNEIKPPIIHYDLKPGNILLVDGTACGEIKITDFGLSKIMDDDSY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EARSIVMQIVNALRYLNEIKPPIIHYDLKPGNILLVDGTACGEIKITDFGLSKIMDDDSY
           470       480       490       500       510       520   

     620       630       640       650       660       670         
pF1KSD GVDGMDLTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFFQCLYGRKPFGHNQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVDGMDLTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFFQCLYGRKPFGHNQS
           530       540       550       560       570       580   

     680       690       700       710       720       730         
pF1KSD QQDILQENTILKATEVQFPVKPVVSSEAKAFIRRCLAYRKEDRFDVHQLANDPYLLPHMR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQDILQENTILKATEVQFPVKPVVSSEAKAFIRRCLAYRKEDRFDVHQLANDPYLLPHMR
           590       600       610       620       630       640   

     740       750       760      
pF1KSD RSNSSGNLHMAGLTASPTPPSSSIITY
       :::::::::::::::::::::::::::
NP_001 RSNSSGNLHMAGLTASPTPPSSSIITY
           650       660       670

>>XP_016860910 (OMIM: 608438) PREDICTED: serine/threonin  (549 aa)
 initn: 3674 init1: 3674 opt: 3674  Z-score: 1470.0  bits: 282.3 E(85289): 3.8e-75
Smith-Waterman score: 3674; 100.0% identity (100.0% similar) in 549 aa overlap (218-766:1-549)

       190       200       210       220       230       240       
pF1KSD SPSPTALAFGDHPIVQPKQLSFKIIQTDLTMLKLAALESNKIQDLEKKEGRIDDLLRANC
                                     ::::::::::::::::::::::::::::::
XP_016                               MLKLAALESNKIQDLEKKEGRIDDLLRANC
                                             10        20        30

       250       260       270       280       290       300       
pF1KSD DLRRQIDEQQKLLEKYKERLNKCISMSKKLLIEKSTQEKLSSREKSMQDRLRLGHFTTVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLRRQIDEQQKLLEKYKERLNKCISMSKKLLIEKSTQEKLSSREKSMQDRLRLGHFTTVR
               40        50        60        70        80        90

       310       320       330       340       350       360       
pF1KSD HGASFTEQWTDGFAFQNLVKQQEWVNQQREDIERQRKLLAKRKPPTANNSQAPSTNSEPK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HGASFTEQWTDGFAFQNLVKQQEWVNQQREDIERQRKLLAKRKPPTANNSQAPSTNSEPK
              100       110       120       130       140       150

       370       380       390       400       410       420       
pF1KSD QRKNKAVNGAENDPFVRPNLPQLLTLAEYHEQEEIFKLRLGHLKKEEAEIQAELERLERV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QRKNKAVNGAENDPFVRPNLPQLLTLAEYHEQEEIFKLRLGHLKKEEAEIQAELERLERV
              160       170       180       190       200       210

       430       440       450       460       470       480       
pF1KSD RNLHIRELKRINNEDNSQFKDHPTLNERYLLLHLLGRGGFSEVYKAFDLYEQRYAAVKIH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RNLHIRELKRINNEDNSQFKDHPTLNERYLLLHLLGRGGFSEVYKAFDLYEQRYAAVKIH
              220       230       240       250       260       270

       490       500       510       520       530       540       
pF1KSD QLNKSWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDTFCTVLEYCEGNDLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLNKSWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDTFCTVLEYCEGNDLD
              280       290       300       310       320       330

       550       560       570       580       590       600       
pF1KSD FYLKQHKLMSEKEARSIVMQIVNALRYLNEIKPPIIHYDLKPGNILLVDGTACGEIKITD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FYLKQHKLMSEKEARSIVMQIVNALRYLNEIKPPIIHYDLKPGNILLVDGTACGEIKITD
              340       350       360       370       380       390

       610       620       630       640       650       660       
pF1KSD FGLSKIMDDDSYGVDGMDLTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFFQC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FGLSKIMDDDSYGVDGMDLTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFFQC
              400       410       420       430       440       450

       670       680       690       700       710       720       
pF1KSD LYGRKPFGHNQSQQDILQENTILKATEVQFPVKPVVSSEAKAFIRRCLAYRKEDRFDVHQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYGRKPFGHNQSQQDILQENTILKATEVQFPVKPVVSSEAKAFIRRCLAYRKEDRFDVHQ
              460       470       480       490       500       510

       730       740       750       760      
pF1KSD LANDPYLLPHMRRSNSSGNLHMAGLTASPTPPSSSIITY
       :::::::::::::::::::::::::::::::::::::::
XP_016 LANDPYLLPHMRRSNSSGNLHMAGLTASPTPPSSSIITY
              520       530       540         

>>XP_016860911 (OMIM: 608438) PREDICTED: serine/threonin  (549 aa)
 initn: 3674 init1: 3674 opt: 3674  Z-score: 1470.0  bits: 282.3 E(85289): 3.8e-75
Smith-Waterman score: 3674; 100.0% identity (100.0% similar) in 549 aa overlap (218-766:1-549)

       190       200       210       220       230       240       
pF1KSD SPSPTALAFGDHPIVQPKQLSFKIIQTDLTMLKLAALESNKIQDLEKKEGRIDDLLRANC
                                     ::::::::::::::::::::::::::::::
XP_016                               MLKLAALESNKIQDLEKKEGRIDDLLRANC
                                             10        20        30

       250       260       270       280       290       300       
pF1KSD DLRRQIDEQQKLLEKYKERLNKCISMSKKLLIEKSTQEKLSSREKSMQDRLRLGHFTTVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLRRQIDEQQKLLEKYKERLNKCISMSKKLLIEKSTQEKLSSREKSMQDRLRLGHFTTVR
               40        50        60        70        80        90

       310       320       330       340       350       360       
pF1KSD HGASFTEQWTDGFAFQNLVKQQEWVNQQREDIERQRKLLAKRKPPTANNSQAPSTNSEPK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HGASFTEQWTDGFAFQNLVKQQEWVNQQREDIERQRKLLAKRKPPTANNSQAPSTNSEPK
              100       110       120       130       140       150

       370       380       390       400       410       420       
pF1KSD QRKNKAVNGAENDPFVRPNLPQLLTLAEYHEQEEIFKLRLGHLKKEEAEIQAELERLERV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QRKNKAVNGAENDPFVRPNLPQLLTLAEYHEQEEIFKLRLGHLKKEEAEIQAELERLERV
              160       170       180       190       200       210

       430       440       450       460       470       480       
pF1KSD RNLHIRELKRINNEDNSQFKDHPTLNERYLLLHLLGRGGFSEVYKAFDLYEQRYAAVKIH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RNLHIRELKRINNEDNSQFKDHPTLNERYLLLHLLGRGGFSEVYKAFDLYEQRYAAVKIH
              220       230       240       250       260       270

       490       500       510       520       530       540       
pF1KSD QLNKSWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDTFCTVLEYCEGNDLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLNKSWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDTFCTVLEYCEGNDLD
              280       290       300       310       320       330

       550       560       570       580       590       600       
pF1KSD FYLKQHKLMSEKEARSIVMQIVNALRYLNEIKPPIIHYDLKPGNILLVDGTACGEIKITD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FYLKQHKLMSEKEARSIVMQIVNALRYLNEIKPPIIHYDLKPGNILLVDGTACGEIKITD
              340       350       360       370       380       390

       610       620       630       640       650       660       
pF1KSD FGLSKIMDDDSYGVDGMDLTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFFQC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FGLSKIMDDDSYGVDGMDLTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFFQC
              400       410       420       430       440       450

       670       680       690       700       710       720       
pF1KSD LYGRKPFGHNQSQQDILQENTILKATEVQFPVKPVVSSEAKAFIRRCLAYRKEDRFDVHQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYGRKPFGHNQSQQDILQENTILKATEVQFPVKPVVSSEAKAFIRRCLAYRKEDRFDVHQ
              460       470       480       490       500       510

       730       740       750       760      
pF1KSD LANDPYLLPHMRRSNSSGNLHMAGLTASPTPPSSSIITY
       :::::::::::::::::::::::::::::::::::::::
XP_016 LANDPYLLPHMRRSNSSGNLHMAGLTASPTPPSSSIITY
              520       530       540         

>>XP_011522522 (OMIM: 608439) PREDICTED: serine/threonin  (709 aa)
 initn: 3197 init1: 1487 opt: 2586  Z-score: 1043.0  bits: 203.6 E(85289): 2.4e-51
Smith-Waterman score: 3352; 72.4% identity (84.3% similar) in 733 aa overlap (49-762:2-706)

       20        30        40        50        60        70        
pF1KSD LSTSPTPGSAAAARSLLNHTPPSGRPREGAMDELHSLDPRRQELLEARFTGVASGSTGST
                                     :.::::::::::::::::::::.       
XP_011                              MMEELHSLDPRRQELLEARFTGVGV------
                                            10        20           

       80        90       100       110       120       130        
pF1KSD GSCSVGAKASTNNESSNHSFGSLGSLSDKESETPEKKQSESSRGRKRKAENQNESSQGKS
             .:.  :.::::.:. :.::::::: :::::::... :.::::::   :.::::.
XP_011 ------SKGPLNSESSNQSLCSVGSLSDKEVETPEKKQNDQ-RNRKRKAEPY-ETSQGKG
                30        40        50        60         70        

      140       150         160       170        180         190   
pF1KSD IGGRGHKISDYFEYQGGN--GSSPVRGIPPAIRS-PQNSHSHSTPSSSVRP--NSPSPTA
          ::::::::::. ::.  :.:: :..::. :: ::.: :.  :    .:  .  . .:
XP_011 TP-RGHKISDYFEFAGGSAPGTSPGRSVPPVARSSPQHSLSNPLPRRVEQPLYGLDGSAA
         80        90       100       110       120       130      

           200       210       220       230       240       250   
pF1KSD LAFGDHPIVQPKQLSFKIIQTDLTMLKLAALESNKIQDLEKKEGRIDDLLRANCDLRRQI
           ..  . :  .:  . .  :   .::          ..  :    .. :::::::::
XP_011 KEATEEQSALPTLMSVMLAKPRLDTEQLA----------QRGAGLCFTFVSANCDLRRQI
        140       150       160                 170       180      

           260       270       280       290       300       310   
pF1KSD DEQQKLLEKYKERLNKCISMSKKLLIEKSTQEKLSSREKSMQDRLRLGHFTTVRHGASFT
       :::::.:::::::::.:..:::::::::: :::.. :.::::::::::::::::::::::
XP_011 DEQQKMLEKYKERLNRCVTMSKKLLIEKSKQEKMACRDKSMQDRLRLGHFTTVRHGASFT
        190       200       210       220       230       240      

           320       330       340       350       360       370   
pF1KSD EQWTDGFAFQNLVKQQEWVNQQREDIERQRKLLAKRKPPTANNSQAPSTNSEPKQRKNKA
       ::::::.:::::.:::: .:.:::.::::::.:::::::. .  ::: ...: ::::.:.
XP_011 EQWTDGYAFQNLIKQQERINSQREEIERQRKMLAKRKPPAMG--QAPPATNEQKQRKSKT
        250       260       270       280         290       300    

           380             390              400       410       420
pF1KSD VNGAEND-PF-----VRPNLPQL-------LTLAEYHEQEEIFKLRLGHLKKEEAEIQAE
        :::::. :      .. . : :       ::::::::::::::::::::::::::::::
XP_011 -NGAENETPSSGNTELKDTAPALGAHSLLRLTLAEYHEQEEIFKLRLGHLKKEEAEIQAE
           310       320       330       340       350       360   

              430       440       450       460       470       480
pF1KSD LERLERVRNLHIRELKRINNEDNSQFKDHPTLNERYLLLHLLGRGGFSEVYKAFDLYEQR
       ::::::::::::::::::.::::::::::::::.:::::::::::::::::::::: :::
XP_011 LERLERVRNLHIRELKRIHNEDNSQFKDHPTLNDRYLLLHLLGRGGFSEVYKAFDLTEQR
           370       380       390       400       410       420   

              490       500       510       520       530       540
pF1KSD YAAVKIHQLNKSWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDTFCTVLEY
       :.:::::::::.::::::::::::::::::::::::::::::::::::::::.:::::::
XP_011 YVAVKIHQLNKNWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDSFCTVLEY
           430       440       450       460       470       480   

              550       560       570       580       590       600
pF1KSD CEGNDLDFYLKQHKLMSEKEARSIVMQIVNALRYLNEIKPPIIHYDLKPGNILLVDGTAC
       ::::::::::::::::::::::::.:::::::.::::::::::::::::::::::.::::
XP_011 CEGNDLDFYLKQHKLMSEKEARSIIMQIVNALKYLNEIKPPIIHYDLKPGNILLVNGTAC
           490       500       510       520       530       540   

              610       620        630       640       650         
pF1KSD GEIKITDFGLSKIMDDDSYG-VDGMDLTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWS
       :::::::::::::::::::. ::::.::::::::::::::::::::::::::::::::::
XP_011 GEIKITDFGLSKIMDDDSYNSVDGMELTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWS
           550       560       570       580       590       600   

     660       670       680       690       700       710         
pF1KSD VGVIFFQCLYGRKPFGHNQSQQDILQENTILKATEVQFPVKPVVSSEAKAFIRRCLAYRK
       :::::.::::::::::::::::::::::::::::::::: ::::. ::::::::::::::
XP_011 VGVIFYQCLYGRKPFGHNQSQQDILQENTILKATEVQFPPKPVVTPEAKAFIRRCLAYRK
           610       620       630       640       650       660   

     720       730       740       750       760      
pF1KSD EDRFDVHQLANDPYLLPHMRRSNSSGNLHMAGLTASPTPPSSSIITY
       :::.::.::: :::::::.:.: :...   :.....    ..:    
XP_011 EDRIDVQQLACDPYLLPHIRKSVSTSSPAGAAIASTSGASNNSSSN 
           670       680       690       700          

>>XP_011510540 (OMIM: 608438) PREDICTED: serine/threonin  (703 aa)
 initn: 4664 init1: 2541 opt: 2558  Z-score: 1032.0  bits: 201.6 E(85289): 9.5e-51
Smith-Waterman score: 4542; 91.8% identity (91.8% similar) in 766 aa overlap (1-766:1-703)

               10        20        30        40        50        60
pF1KSD MSVQSSSGSLEGPPSWSQLSTSPTPGSAAAARSLLNHTPPSGRPREGAMDELHSLDPRRQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSVQSSSGSLEGPPSWSQLSTSPTPGSAAAARSLLNHTPPSGRPREGAMDELHSLDPRRQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD ELLEARFTGVASGSTGSTGSCSVGAKASTNNESSNHSFGSLGSLSDKESETPEKKQSESS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELLEARFTGVASGSTGSTGSCSVGAKASTNNESSNHSFGSLGSLSDKESETPEKKQSESS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD RGRKRKAENQNESSQGKSIGGRGHKISDYFEYQGGNGSSPVRGIPPAIRSPQNSHSHSTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RGRKRKAENQNESSQGKSIGGRGHKISDYFEYQGGNGSSPVRGIPPAIRSPQNSHSHSTP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD SSSVRPNSPSPTALAFGDHPIVQPKQLSFKIIQTDLTMLKLAALESNKIQDLEKKEGRID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSSVRPNSPSPTALAFGDHPIVQPKQLSFKIIQTDLTMLKLAALESNKIQDLEKKEGRID
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD DLLRANCDLRRQIDEQQKLLEKYKERLNKCISMSKKLLIEKSTQEKLSSREKSMQDRLRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLLRANCDLRRQIDEQQKLLEKYKERLNKCISMSKKLLIEKSTQEKLSSREKSMQDRLRL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD GHFTTVRHGASFTEQWTDGFAFQNLVKQQEWVNQQREDIERQRKLLAKRKPPTANNSQAP
       :::::::::::::::::::::::::::                                 
XP_011 GHFTTVRHGASFTEQWTDGFAFQNLVK---------------------------------
              310       320                                        

              370       380       390       400       410       420
pF1KSD STNSEPKQRKNKAVNGAENDPFVRPNLPQLLTLAEYHEQEEIFKLRLGHLKKEEAEIQAE
                                     ::::::::::::::::::::::::::::::
XP_011 ------------------------------LTLAEYHEQEEIFKLRLGHLKKEEAEIQAE
                                     330       340       350       

              430       440       450       460       470       480
pF1KSD LERLERVRNLHIRELKRINNEDNSQFKDHPTLNERYLLLHLLGRGGFSEVYKAFDLYEQR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LERLERVRNLHIRELKRINNEDNSQFKDHPTLNERYLLLHLLGRGGFSEVYKAFDLYEQR
       360       370       380       390       400       410       

              490       500       510       520       530       540
pF1KSD YAAVKIHQLNKSWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDTFCTVLEY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YAAVKIHQLNKSWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDTFCTVLEY
       420       430       440       450       460       470       

              550       560       570       580       590       600
pF1KSD CEGNDLDFYLKQHKLMSEKEARSIVMQIVNALRYLNEIKPPIIHYDLKPGNILLVDGTAC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CEGNDLDFYLKQHKLMSEKEARSIVMQIVNALRYLNEIKPPIIHYDLKPGNILLVDGTAC
       480       490       500       510       520       530       

              610       620       630       640       650       660
pF1KSD GEIKITDFGLSKIMDDDSYGVDGMDLTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GEIKITDFGLSKIMDDDSYGVDGMDLTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSV
       540       550       560       570       580       590       

              670       680       690       700       710       720
pF1KSD GVIFFQCLYGRKPFGHNQSQQDILQENTILKATEVQFPVKPVVSSEAKAFIRRCLAYRKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GVIFFQCLYGRKPFGHNQSQQDILQENTILKATEVQFPVKPVVSSEAKAFIRRCLAYRKE
       600       610       620       630       640       650       

              730       740       750       760      
pF1KSD DRFDVHQLANDPYLLPHMRRSNSSGNLHMAGLTASPTPPSSSIITY
       ::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DRFDVHQLANDPYLLPHMRRSNSSGNLHMAGLTASPTPPSSSIITY
       660       670       680       690       700   

>>XP_011522525 (OMIM: 608439) PREDICTED: serine/threonin  (709 aa)
 initn: 3218 init1: 1487 opt: 2489  Z-score: 1005.0  bits: 196.6 E(85289): 3.1e-49
Smith-Waterman score: 3243; 71.0% identity (84.3% similar) in 731 aa overlap (49-762:2-706)

       20        30        40        50        60        70        
pF1KSD LSTSPTPGSAAAARSLLNHTPPSGRPREGAMDELHSLDPRRQELLEARFTGVASGSTGST
                                     :.::::::::::::::::::::.       
XP_011                              MMEELHSLDPRRQELLEARFTGVGV------
                                            10        20           

       80        90       100       110       120       130        
pF1KSD GSCSVGAKASTNNESSNHSFGSLGSLSDKESETPEKKQSESSRGRKRKAENQNESSQGKS
             .:.  :.::::.:. :.::::::: :::::::... :.::::::   :.::::.
XP_011 ------SKGPLNSESSNQSLCSVGSLSDKEVETPEKKQNDQ-RNRKRKAE-PYETSQGKG
                30        40        50        60          70       

      140       150       160       170       180        190       
pF1KSD IGGRGHKISDYFEYQGGNGSSPVRGIPPAIRSPQNSHSHSTPS-SSVRPNSPSPTALAFG
          :::::::::: .     .:. :.  .  .  . .. . :.  ::   .:      . 
XP_011 TP-RGHKISDYFERR---VEQPLYGLDGSAAKEATEEQSALPTLMSVMLAKPR-----LD
         80        90          100       110       120             

       200        210       220       230       240        250     
pF1KSD DHPIVQ-PKQLSFKIIQTDLTMLKLAALESNKIQDLEKKEGRIDD-LLRANCDLRRQIDE
        . ..:    : : ..... .  . ..  ... .   .:.  :.    .:::::::::::
XP_011 TEQLAQRGAGLCFTFVSAQQNSPSSTGSGNTEHSCSSQKQISIQHRQTQANCDLRRQIDE
      130       140       150       160       170       180        

         260       270       280       290       300       310     
pF1KSD QQKLLEKYKERLNKCISMSKKLLIEKSTQEKLSSREKSMQDRLRLGHFTTVRHGASFTEQ
       :::.:::::::::.:..:::::::::: :::.. :.::::::::::::::::::::::::
XP_011 QQKMLEKYKERLNRCVTMSKKLLIEKSKQEKMACRDKSMQDRLRLGHFTTVRHGASFTEQ
      190       200       210       220       230       240        

         320       330       340       350       360       370     
pF1KSD WTDGFAFQNLVKQQEWVNQQREDIERQRKLLAKRKPPTANNSQAPSTNSEPKQRKNKAVN
       ::::.:::::.:::: .:.:::.::::::.:::::::. .  ::: ...: ::::.:. :
XP_011 WTDGYAFQNLIKQQERINSQREEIERQRKMLAKRKPPAMG--QAPPATNEQKQRKSKT-N
      250       260       270       280         290       300      

         380             390              400       410       420  
pF1KSD GAEND-PF-----VRPNLPQL-------LTLAEYHEQEEIFKLRLGHLKKEEAEIQAELE
       ::::. :      .. . : :       ::::::::::::::::::::::::::::::::
XP_011 GAENETPSSGNTELKDTAPALGAHSLLRLTLAEYHEQEEIFKLRLGHLKKEEAEIQAELE
         310       320       330       340       350       360     

            430       440       450       460       470       480  
pF1KSD RLERVRNLHIRELKRINNEDNSQFKDHPTLNERYLLLHLLGRGGFSEVYKAFDLYEQRYA
       ::::::::::::::::.::::::::::::::.:::::::::::::::::::::: ::::.
XP_011 RLERVRNLHIRELKRIHNEDNSQFKDHPTLNDRYLLLHLLGRGGFSEVYKAFDLTEQRYV
         370       380       390       400       410       420     

            490       500       510       520       530       540  
pF1KSD AVKIHQLNKSWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDTFCTVLEYCE
       :::::::::.::::::::::::::::::::::::::::::::::::::::.:::::::::
XP_011 AVKIHQLNKNWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDSFCTVLEYCE
         430       440       450       460       470       480     

            550       560       570       580       590       600  
pF1KSD GNDLDFYLKQHKLMSEKEARSIVMQIVNALRYLNEIKPPIIHYDLKPGNILLVDGTACGE
       ::::::::::::::::::::::.:::::::.::::::::::::::::::::::.::::::
XP_011 GNDLDFYLKQHKLMSEKEARSIIMQIVNALKYLNEIKPPIIHYDLKPGNILLVNGTACGE
         490       500       510       520       530       540     

            610       620        630       640       650       660 
pF1KSD IKITDFGLSKIMDDDSYG-VDGMDLTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVG
       :::::::::::::::::. ::::.::::::::::::::::::::::::::::::::::::
XP_011 IKITDFGLSKIMDDDSYNSVDGMELTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVG
         550       560       570       580       590       600     

             670       680       690       700       710       720 
pF1KSD VIFFQCLYGRKPFGHNQSQQDILQENTILKATEVQFPVKPVVSSEAKAFIRRCLAYRKED
       :::.::::::::::::::::::::::::::::::::: ::::. ::::::::::::::::
XP_011 VIFYQCLYGRKPFGHNQSQQDILQENTILKATEVQFPPKPVVTPEAKAFIRRCLAYRKED
         610       620       630       640       650       660     

             730       740       750       760      
pF1KSD RFDVHQLANDPYLLPHMRRSNSSGNLHMAGLTASPTPPSSSIITY
       :.::.::: :::::::.:.: :...   :.....    ..:    
XP_011 RIDVQQLACDPYLLPHIRKSVSTSSPAGAAIASTSGASNNSSSN 
         670       680       690       700          

>>XP_016879534 (OMIM: 608439) PREDICTED: serine/threonin  (764 aa)
 initn: 3363 init1: 1488 opt: 2438  Z-score: 984.7  bits: 192.9 E(85289): 4.1e-48
Smith-Waterman score: 3450; 70.5% identity (82.7% similar) in 790 aa overlap (8-762:2-761)

               10        20        30        40                50  
pF1KSD MSVQSSSGSLEGPPSWSQLSTSPTPGSAAAARSLLNHTPPSGRPREGA--------MDEL
              :  .. :.:.  .  :    .  . :   . :: ::::: :        :.::
XP_016       MGEAQAAPAWDW-GRRPEERRGPPG-SWRPRQPP-GRPREPALPSSVTEMMEEL
                     10         20         30         40        50 

             60        70        80        90       100       110  
pF1KSD HSLDPRRQELLEARFTGVASGSTGSTGSCSVGAKASTNNESSNHSFGSLGSLSDKESETP
       ::::::::::::::::::.             .:.  :.::::.:. :.::::::: :::
XP_016 HSLDPRRQELLEARFTGVGV------------SKGPLNSESSNQSLCSVGSLSDKEVETP
              60        70                    80        90         

            120       130       140       150             160      
pF1KSD EKKQSESSRGRKRKAENQNESSQGKSIGGRGHKISDYFEYQ------GGNGSSPVRG---
       ::::... :.::::::   :.::::.   :::::::::: .      : .::.  ..   
XP_016 EKKQNDQ-RNRKRKAEPY-ETSQGKGTP-RGHKISDYFERRVEQPLYGLDGSAAKEATEE
     100        110        120        130       140       150      

                       170          180       190       200        
pF1KSD ---IP---------PAIRSPQNSHSHST---PSSSVRPNSPSPTALAFGDHPIVQPKQLS
          .:         : . . : ..  .       :.. :::: :. .  .:   . ::.:
XP_016 QSALPTLMSVMLAKPRLDTEQLAQRGAGLCFTFVSAQQNSPSSTGSGNTEHSCSSQKQIS
        160       170       180       190       200       210      

        210       220       230       240       250       260      
pF1KSD F--KIIQTDLTMLKLAALESNKIQDLEKKEGRIDDLLRANCDLRRQIDEQQKLLEKYKER
       .  .  :.:::. :..:::..: .::::::::::::::::::::::::::::.:::::::
XP_016 IQHRQTQSDLTIEKISALENSKNSDLEKKEGRIDDLLRANCDLRRQIDEQQKMLEKYKER
        220       230       240       250       260       270      

        270       280       290       300       310       320      
pF1KSD LNKCISMSKKLLIEKSTQEKLSSREKSMQDRLRLGHFTTVRHGASFTEQWTDGFAFQNLV
       ::.:..:::::::::: :::.. :.::::::::::::::::::::::::::::.:::::.
XP_016 LNRCVTMSKKLLIEKSKQEKMACRDKSMQDRLRLGHFTTVRHGASFTEQWTDGYAFQNLI
        280       290       300       310       320       330      

        330       340       350       360       370       380      
pF1KSD KQQEWVNQQREDIERQRKLLAKRKPPTANNSQAPSTNSEPKQRKNKAVNGAENDPFVRPN
       :::: .:.:::.::::::.:::::::.   .::: ...: ::::.:. :::::.      
XP_016 KQQERINSQREEIERQRKMLAKRKPPAM--GQAPPATNEQKQRKSKT-NGAENET-----
        340       350       360         370       380              

        390       400       410       420       430       440      
pF1KSD LPQLLTLAEYHEQEEIFKLRLGHLKKEEAEIQAELERLERVRNLHIRELKRINNEDNSQF
           ::::::::::::::::::::::::::::::::::::::::::::::::.:::::::
XP_016 ----LTLAEYHEQEEIFKLRLGHLKKEEAEIQAELERLERVRNLHIRELKRIHNEDNSQF
          390       400       410       420       430       440    

        450       460       470       480       490       500      
pF1KSD KDHPTLNERYLLLHLLGRGGFSEVYKAFDLYEQRYAAVKIHQLNKSWRDEKKENYHKHAC
       :::::::.:::::::::::::::::::::: ::::.:::::::::.::::::::::::::
XP_016 KDHPTLNDRYLLLHLLGRGGFSEVYKAFDLTEQRYVAVKIHQLNKNWRDEKKENYHKHAC
          450       460       470       480       490       500    

        510       520       530       540       550       560      
pF1KSD REYRIHKELDHPRIVKLYDYFSLDTDTFCTVLEYCEGNDLDFYLKQHKLMSEKEARSIVM
       ::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::.:
XP_016 REYRIHKELDHPRIVKLYDYFSLDTDSFCTVLEYCEGNDLDFYLKQHKLMSEKEARSIIM
          510       520       530       540       550       560    

        570       580       590       600       610       620      
pF1KSD QIVNALRYLNEIKPPIIHYDLKPGNILLVDGTACGEIKITDFGLSKIMDDDSYG-VDGMD
       ::::::.::::::::::::::::::::::.:::::::::::::::::::::::. ::::.
XP_016 QIVNALKYLNEIKPPIIHYDLKPGNILLVNGTACGEIKITDFGLSKIMDDDSYNSVDGME
          570       580       590       600       610       620    

         630       640       650       660       670       680     
pF1KSD LTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFFQCLYGRKPFGHNQSQQDILQ
       :::::::::::::::::::::::::::::::::::::::.::::::::::::::::::::
XP_016 LTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFYQCLYGRKPFGHNQSQQDILQ
          630       640       650       660       670       680    

         690       700       710       720       730       740     
pF1KSD ENTILKATEVQFPVKPVVSSEAKAFIRRCLAYRKEDRFDVHQLANDPYLLPHMRRSNSSG
       ::::::::::::: ::::. :::::::::::::::::.::.::: :::::::.:.: :..
XP_016 ENTILKATEVQFPPKPVVTPEAKAFIRRCLAYRKEDRIDVQQLACDPYLLPHIRKSVSTS
          690       700       710       720       730       740    

         750       760      
pF1KSD NLHMAGLTASPTPPSSSIITY
       .   :.....    ..:    
XP_016 SPAGAAIASTSGASNNSSSN 
          750       760     

>>XP_011522520 (OMIM: 608439) PREDICTED: serine/threonin  (719 aa)
 initn: 3197 init1: 1488 opt: 2427  Z-score: 980.7  bits: 192.1 E(85289): 7e-48
Smith-Waterman score: 3327; 71.6% identity (84.1% similar) in 742 aa overlap (49-762:2-716)

       20        30        40        50        60        70        
pF1KSD LSTSPTPGSAAAARSLLNHTPPSGRPREGAMDELHSLDPRRQELLEARFTGVASGSTGST
                                     :.::::::::::::::::::::.       
XP_011                              MMEELHSLDPRRQELLEARFTGVGV------
                                            10        20           

       80        90       100       110       120       130        
pF1KSD GSCSVGAKASTNNESSNHSFGSLGSLSDKESETPEKKQSESSRGRKRKAENQNESSQGKS
             .:.  :.::::.:. :.::::::: :::::::... :.::::::   :.::::.
XP_011 ------SKGPLNSESSNQSLCSVGSLSDKEVETPEKKQNDQ-RNRKRKAE-PYETSQGKG
                30        40        50        60          70       

      140       150         160       170        180               
pF1KSD IGGRGHKISDYFEYQGGN--GSSPVRGIPPAIRS-PQNSHSHSTPSSSVRP---------
          ::::::::::. ::.  :.:: :..::. :: ::.: :.  :    .:         
XP_011 TP-RGHKISDYFEFAGGSAPGTSPGRSVPPVARSSPQHSLSNPLPRRVEQPLYGLDGSAA
         80        90       100       110       120       130      

              190        200       210       220            230    
pF1KSD ------NSPSPTALAFG-DHPIVQPKQLSFKIIQTDLTMLKL-----AALESNKIQDLEK
             .:  :: ..    .: .. .::. .     .:...      ..  :.. .   .
XP_011 KEATEEQSALPTLMSVMLAKPRLDTEQLAQRGAGLCFTFVSAQQNSPSSTGSGNTEHSCS
        140       150       160       170       180       190      

          240          250       260       270       280       290 
pF1KSD KEGRIDDLLR---ANCDLRRQIDEQQKLLEKYKERLNKCISMSKKLLIEKSTQEKLSSRE
       .. .:.   :   ::::::::::::::.:::::::::.:..:::::::::: :::.. :.
XP_011 SQKQISIQHRQTQANCDLRRQIDEQQKMLEKYKERLNRCVTMSKKLLIEKSKQEKMACRD
        200       210       220       230       240       250      

             300       310       320       330       340       350 
pF1KSD KSMQDRLRLGHFTTVRHGASFTEQWTDGFAFQNLVKQQEWVNQQREDIERQRKLLAKRKP
       ::::::::::::::::::::::::::::.:::::.:::: .:.:::.::::::.::::::
XP_011 KSMQDRLRLGHFTTVRHGASFTEQWTDGYAFQNLIKQQERINSQREEIERQRKMLAKRKP
        260       270       280       290       300       310      

             360       370       380       390       400       410 
pF1KSD PTANNSQAPSTNSEPKQRKNKAVNGAENDPFVRPNLPQLLTLAEYHEQEEIFKLRLGHLK
       :. .  ::: ...: ::::.:. :::::.          :::::::::::::::::::::
XP_011 PAMG--QAPPATNEQKQRKSKT-NGAENET---------LTLAEYHEQEEIFKLRLGHLK
        320         330        340                350       360    

             420       430       440       450       460       470 
pF1KSD KEEAEIQAELERLERVRNLHIRELKRINNEDNSQFKDHPTLNERYLLLHLLGRGGFSEVY
       :::::::::::::::::::::::::::.::::::::::::::.:::::::::::::::::
XP_011 KEEAEIQAELERLERVRNLHIRELKRIHNEDNSQFKDHPTLNDRYLLLHLLGRGGFSEVY
          370       380       390       400       410       420    

             480       490       500       510       520       530 
pF1KSD KAFDLYEQRYAAVKIHQLNKSWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDT
       ::::: ::::.:::::::::.:::::::::::::::::::::::::::::::::::::::
XP_011 KAFDLTEQRYVAVKIHQLNKNWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDT
          430       440       450       460       470       480    

             540       550       560       570       580       590 
pF1KSD DTFCTVLEYCEGNDLDFYLKQHKLMSEKEARSIVMQIVNALRYLNEIKPPIIHYDLKPGN
       :.:::::::::::::::::::::::::::::::.:::::::.::::::::::::::::::
XP_011 DSFCTVLEYCEGNDLDFYLKQHKLMSEKEARSIIMQIVNALKYLNEIKPPIIHYDLKPGN
          490       500       510       520       530       540    

             600       610       620        630       640       650
pF1KSD ILLVDGTACGEIKITDFGLSKIMDDDSYG-VDGMDLTSQGAGTYWYLPPECFVVGKEPPK
       ::::.:::::::::::::::::::::::. ::::.:::::::::::::::::::::::::
XP_011 ILLVNGTACGEIKITDFGLSKIMDDDSYNSVDGMELTSQGAGTYWYLPPECFVVGKEPPK
          550       560       570       580       590       600    

              660       670       680       690       700       710
pF1KSD ISNKVDVWSVGVIFFQCLYGRKPFGHNQSQQDILQENTILKATEVQFPVKPVVSSEAKAF
       ::::::::::::::.::::::::::::::::::::::::::::::::: ::::. :::::
XP_011 ISNKVDVWSVGVIFYQCLYGRKPFGHNQSQQDILQENTILKATEVQFPPKPVVTPEAKAF
          610       620       630       640       650       660    

              720       730       740       750       760      
pF1KSD IRRCLAYRKEDRFDVHQLANDPYLLPHMRRSNSSGNLHMAGLTASPTPPSSSIITY
       ::::::::::::.::.::: :::::::.:.: :...   :.....    ..:    
XP_011 IRRCLAYRKEDRIDVQQLACDPYLLPHIRKSVSTSSPAGAAIASTSGASNNSSSN 
          670       680       690       700       710          




766 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 00:10:58 2016 done: Thu Nov  3 00:10:59 2016
 Total Scan time:  9.000 Total Display time:  0.170

Function used was FASTA [36.3.4 Apr, 2011]
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