Result of FASTA (omim) for pF1KSDA0080
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KSDA0080, 431 aa
  1>>>pF1KSDA0080 431 - 431 aa - 431 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.2399+/-0.000438; mu= 12.7973+/- 0.027
 mean_var=123.0567+/-25.385, 0's: 0 Z-trim(114.3): 307  B-trim: 410 in 1/50
 Lambda= 0.115617
 statistics sampled from 23679 (24117) to 23679 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.662), E-opt: 0.2 (0.283), width:  16
 Scan time:  7.350

The best scores are:                                      opt bits E(85289)
NP_689493 (OMIM: 608741) synaptotagmin-11 [Homo sa ( 431) 2851 487.3 3.3e-137
XP_016856248 (OMIM: 608741) PREDICTED: synaptotagm ( 434) 2830 483.8 3.8e-136
XP_005245071 (OMIM: 608741) PREDICTED: synaptotagm ( 430) 2826 483.1  6e-136
NP_065834 (OMIM: 600103) synaptotagmin-4 [Homo sap ( 425) 1497 261.4 3.2e-69
XP_006723404 (OMIM: 600782) PREDICTED: synaptotagm ( 383)  815 147.6 5.2e-35
NP_001284703 (OMIM: 600782) synaptotagmin-5 isofor ( 382)  811 146.9 8.2e-35
XP_016882665 (OMIM: 600782) PREDICTED: synaptotagm ( 386)  797 144.6 4.2e-34
NP_003171 (OMIM: 600782) synaptotagmin-5 isoform 1 ( 386)  797 144.6 4.2e-34
XP_006723402 (OMIM: 600782) PREDICTED: synaptotagm ( 386)  797 144.6 4.2e-34
XP_016882664 (OMIM: 600782) PREDICTED: synaptotagm ( 386)  797 144.6 4.2e-34
XP_006723403 (OMIM: 600782) PREDICTED: synaptotagm ( 385)  793 143.9 6.6e-34
XP_005269170 (OMIM: 185605) PREDICTED: synaptotagm ( 419)  788 143.1 1.3e-33
XP_006719639 (OMIM: 185605) PREDICTED: synaptotagm ( 419)  788 143.1 1.3e-33
NP_001278830 (OMIM: 185605) synaptotagmin-1 isofor ( 419)  788 143.1 1.3e-33
NP_796376 (OMIM: 600104,616040) synaptotagmin-2 [H ( 419)  787 143.0 1.4e-33
XP_016855802 (OMIM: 600104,616040) PREDICTED: syna ( 419)  787 143.0 1.4e-33
NP_001129976 (OMIM: 600104,616040) synaptotagmin-2 ( 419)  787 143.0 1.4e-33
XP_016855799 (OMIM: 600104,616040) PREDICTED: syna ( 476)  787 143.0 1.5e-33
NP_005630 (OMIM: 185605) synaptotagmin-1 isoform 1 ( 422)  785 142.6 1.8e-33
XP_011537012 (OMIM: 185605) PREDICTED: synaptotagm ( 422)  785 142.6 1.8e-33
NP_001129277 (OMIM: 185605) synaptotagmin-1 isofor ( 422)  785 142.6 1.8e-33
XP_016875398 (OMIM: 185605) PREDICTED: synaptotagm ( 422)  785 142.6 1.8e-33
NP_001129278 (OMIM: 185605) synaptotagmin-1 isofor ( 422)  785 142.6 1.8e-33
XP_016855801 (OMIM: 600104,616040) PREDICTED: syna ( 422)  783 142.3 2.3e-33
XP_011507494 (OMIM: 600104,616040) PREDICTED: syna ( 422)  783 142.3 2.3e-33
XP_016855800 (OMIM: 600104,616040) PREDICTED: syna ( 422)  783 142.3 2.3e-33
XP_016855798 (OMIM: 600104,616040) PREDICTED: syna ( 479)  783 142.4 2.5e-33
XP_006718799 (OMIM: 604146) PREDICTED: synaptotagm ( 293)  773 140.5 5.5e-33
NP_004191 (OMIM: 604146) synaptotagmin-7 isoform 2 ( 403)  774 140.8 6.2e-33
XP_011543645 (OMIM: 604146) PREDICTED: synaptotagm ( 409)  774 140.8 6.2e-33
NP_001287702 (OMIM: 604146) synaptotagmin-7 isofor ( 447)  774 140.8 6.6e-33
XP_005274444 (OMIM: 604146) PREDICTED: synaptotagm ( 449)  774 140.8 6.7e-33
XP_011543643 (OMIM: 604146) PREDICTED: synaptotagm ( 453)  774 140.8 6.7e-33
NP_001238994 (OMIM: 604146) synaptotagmin-7 isofor ( 478)  774 140.9   7e-33
XP_011543642 (OMIM: 604146) PREDICTED: synaptotagm ( 484)  774 140.9   7e-33
XP_011543641 (OMIM: 604146) PREDICTED: synaptotagm ( 528)  774 140.9 7.5e-33
XP_005274442 (OMIM: 604146) PREDICTED: synaptotagm ( 611)  774 141.0 8.3e-33
XP_011543640 (OMIM: 604146) PREDICTED: synaptotagm ( 617)  774 141.0 8.4e-33
XP_005274441 (OMIM: 604146) PREDICTED: synaptotagm ( 642)  774 141.0 8.6e-33
XP_011543639 (OMIM: 604146) PREDICTED: synaptotagm ( 648)  774 141.0 8.7e-33
XP_011543638 (OMIM: 604146) PREDICTED: synaptotagm ( 651)  774 141.0 8.7e-33
XP_005274440 (OMIM: 604146) PREDICTED: synaptotagm ( 686)  774 141.0   9e-33
XP_011543637 (OMIM: 604146) PREDICTED: synaptotagm ( 692)  774 141.0 9.1e-33
NP_001257734 (OMIM: 607718) synaptotagmin-6 [Homo  ( 425)  750 136.8   1e-31
NP_995320 (OMIM: 607718) synaptotagmin-6 [Homo sap ( 425)  750 136.8   1e-31
XP_016855860 (OMIM: 607718) PREDICTED: synaptotagm ( 443)  750 136.8 1.1e-31
XP_011525692 (OMIM: 600327) PREDICTED: synaptotagm ( 590)  724 132.6 2.6e-30
NP_115674 (OMIM: 600327) synaptotagmin-3 [Homo sap ( 590)  724 132.6 2.6e-30
XP_011525693 (OMIM: 600327) PREDICTED: synaptotagm ( 590)  724 132.6 2.6e-30
NP_001153801 (OMIM: 600327) synaptotagmin-3 [Homo  ( 590)  724 132.6 2.6e-30


>>NP_689493 (OMIM: 608741) synaptotagmin-11 [Homo sapien  (431 aa)
 initn: 2851 init1: 2851 opt: 2851  Z-score: 2584.3  bits: 487.3 E(85289): 3.3e-137
Smith-Waterman score: 2851; 99.8% identity (100.0% similar) in 431 aa overlap (1-431:1-431)

               10        20        30        40        50        60
pF1KSD MAEITNIRPSFDVSPVVAGLIGASVLVVCVSVTVFVWSCCHQQAEKKHKNPPYKFIHMLK
       :::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::
NP_689 MAEITNIRPSFDVSPVVAGLIGASVLVVCVSVTVFVWSCCHQQAEKKQKNPPYKFIHMLK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD GISIYPETLSNKKKIIKVRRDKDGPGREGGRRNLLVDAAEAGLLSRDKDPRGPSSGSCID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 GISIYPETLSNKKKIIKVRRDKDGPGREGGRRNLLVDAAEAGLLSRDKDPRGPSSGSCID
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD QLPIKMDYGEELRSPITSLTPGESKTTSPSSPEEDVMLGSLTFSVDYNFPKKALVVTIQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 QLPIKMDYGEELRSPITSLTPGESKTTSPSSPEEDVMLGSLTFSVDYNFPKKALVVTIQE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD AHGLPVMDDQTQGSDPYIKMTILPDKRHRVKTRVLRKTLDPVFDETFTFYGIPYSQLQDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 AHGLPVMDDQTQGSDPYIKMTILPDKRHRVKTRVLRKTLDPVFDETFTFYGIPYSQLQDL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD VLHFLVLSFDRFSRDDVIGEVMVPLAGVDPSTGKVQLTRDIIKRNIQKCISRGELQVSLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 VLHFLVLSFDRFSRDDVIGEVMVPLAGVDPSTGKVQLTRDIIKRNIQKCISRGELQVSLS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD YQPVAQRMTVVVLKARHLPKMDITGLSGNPYVKVNVYYGRKRIAKKKTHVKKCTLNPIFN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 YQPVAQRMTVVVLKARHLPKMDITGLSGNPYVKVNVYYGRKRIAKKKTHVKKCTLNPIFN
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD ESFIYDIPTDLLPDISIEFLVIDFDRTTKNEVVGRLILGAHSVTASGAEHWREVCESPRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 ESFIYDIPTDLLPDISIEFLVIDFDRTTKNEVVGRLILGAHSVTASGAEHWREVCESPRK
              370       380       390       400       410       420

              430 
pF1KSD PVAKWHSLSEY
       :::::::::::
NP_689 PVAKWHSLSEY
              430 

>>XP_016856248 (OMIM: 608741) PREDICTED: synaptotagmin-1  (434 aa)
 initn: 2157 init1: 2157 opt: 2830  Z-score: 2565.3  bits: 483.8 E(85289): 3.8e-136
Smith-Waterman score: 2830; 98.8% identity (99.3% similar) in 434 aa overlap (1-431:1-434)

               10        20        30        40        50        60
pF1KSD MAEITNIRPSFDVSPVVAGLIGASVLVVCVSVTVFVWSCCHQQAEKKHKNPPYKFIHMLK
       :::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::
XP_016 MAEITNIRPSFDVSPVVAGLIGASVLVVCVSVTVFVWSCCHQQAEKKQKNPPYKFIHMLK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD GISIYPETLSNKKKIIKVRRDKDGPGREGGRRNLLVDAAEAGLLSRDKDPRGPSSGSCID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GISIYPETLSNKKKIIKVRRDKDGPGREGGRRNLLVDAAEAGLLSRDKDPRGPSSGSCID
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD QLPIKMDYGEELRSPITSLTPGESKTTSPSSPEEDVMLGSLTFSVDYNFPKKALVVTIQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLPIKMDYGEELRSPITSLTPGESKTTSPSSPEEDVMLGSLTFSVDYNFPKKALVVTIQE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD AHGLPVMDDQTQGSDPYIKMTILPDKRHRVKTRVLRKTLDPVFDETFTFYGIPYSQLQDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AHGLPVMDDQTQGSDPYIKMTILPDKRHRVKTRVLRKTLDPVFDETFTFYGIPYSQLQDL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD VLHFLVLSFDRFSRDDVIGEVMVPLAGVDPSTGKVQLTRDIIKRNIQKCISRGELQVSLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLHFLVLSFDRFSRDDVIGEVMVPLAGVDPSTGKVQLTRDIIKRNIQKCISRGELQVSLS
              250       260       270       280       290       300

              310       320          330       340       350       
pF1KSD YQPVAQRMTVVVLKARHLPKMDITGLSG---NPYVKVNVYYGRKRIAKKKTHVKKCTLNP
       ::::::::::::::::::::::::::::   .::::::::::::::::::::::::::::
XP_016 YQPVAQRMTVVVLKARHLPKMDITGLSGRAPDPYVKVNVYYGRKRIAKKKTHVKKCTLNP
              310       320       330       340       350       360

       360       370       380       390       400       410       
pF1KSD IFNESFIYDIPTDLLPDISIEFLVIDFDRTTKNEVVGRLILGAHSVTASGAEHWREVCES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IFNESFIYDIPTDLLPDISIEFLVIDFDRTTKNEVVGRLILGAHSVTASGAEHWREVCES
              370       380       390       400       410       420

       420       430 
pF1KSD PRKPVAKWHSLSEY
       ::::::::::::::
XP_016 PRKPVAKWHSLSEY
              430    

>>XP_005245071 (OMIM: 608741) PREDICTED: synaptotagmin-1  (430 aa)
 initn: 2149 init1: 2149 opt: 2826  Z-score: 2561.7  bits: 483.1 E(85289): 6e-136
Smith-Waterman score: 2826; 99.3% identity (99.8% similar) in 431 aa overlap (1-431:1-430)

               10        20        30        40        50        60
pF1KSD MAEITNIRPSFDVSPVVAGLIGASVLVVCVSVTVFVWSCCHQQAEKKHKNPPYKFIHMLK
       :::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::
XP_005 MAEITNIRPSFDVSPVVAGLIGASVLVVCVSVTVFVWSCCHQQAEKKQKNPPYKFIHMLK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD GISIYPETLSNKKKIIKVRRDKDGPGREGGRRNLLVDAAEAGLLSRDKDPRGPSSGSCID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GISIYPETLSNKKKIIKVRRDKDGPGREGGRRNLLVDAAEAGLLSRDKDPRGPSSGSCID
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD QLPIKMDYGEELRSPITSLTPGESKTTSPSSPEEDVMLGSLTFSVDYNFPKKALVVTIQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QLPIKMDYGEELRSPITSLTPGESKTTSPSSPEEDVMLGSLTFSVDYNFPKKALVVTIQE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD AHGLPVMDDQTQGSDPYIKMTILPDKRHRVKTRVLRKTLDPVFDETFTFYGIPYSQLQDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AHGLPVMDDQTQGSDPYIKMTILPDKRHRVKTRVLRKTLDPVFDETFTFYGIPYSQLQDL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD VLHFLVLSFDRFSRDDVIGEVMVPLAGVDPSTGKVQLTRDIIKRNIQKCISRGELQVSLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VLHFLVLSFDRFSRDDVIGEVMVPLAGVDPSTGKVQLTRDIIKRNIQKCISRGELQVSLS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD YQPVAQRMTVVVLKARHLPKMDITGLSGNPYVKVNVYYGRKRIAKKKTHVKKCTLNPIFN
       ::::::::::::::::::::::::::: .:::::::::::::::::::::::::::::::
XP_005 YQPVAQRMTVVVLKARHLPKMDITGLS-DPYVKVNVYYGRKRIAKKKTHVKKCTLNPIFN
              310       320        330       340       350         

              370       380       390       400       410       420
pF1KSD ESFIYDIPTDLLPDISIEFLVIDFDRTTKNEVVGRLILGAHSVTASGAEHWREVCESPRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ESFIYDIPTDLLPDISIEFLVIDFDRTTKNEVVGRLILGAHSVTASGAEHWREVCESPRK
     360       370       380       390       400       410         

              430 
pF1KSD PVAKWHSLSEY
       :::::::::::
XP_005 PVAKWHSLSEY
     420       430

>>NP_065834 (OMIM: 600103) synaptotagmin-4 [Homo sapiens  (425 aa)
 initn: 1124 init1: 825 opt: 1497  Z-score: 1363.8  bits: 261.4 E(85289): 3.2e-69
Smith-Waterman score: 1497; 53.0% identity (79.5% similar) in 434 aa overlap (1-430:1-424)

               10        20        30        40        50        60
pF1KSD MAEITNIRPSFDVSPVVAGLIGASVLVVCVSVTVFVWSCCHQQAEKKHKNPPYKFIHMLK
       :: ::. :  ::  :.:.:...:  ::  ::.  :.: ::.... :..:.:::::.:.::
NP_065 MAPITTSREEFDEIPTVVGIFSAFGLVFTVSL--FAWICCQRKSSKSNKTPPYKFVHVLK
               10        20        30          40        50        

               70        80          90       100        110       
pF1KSD GISIYPETLSNKKKIIKVRRD--KDGPGREGGRRNLLVDAAEAGLLSR-DKDPRGPSSGS
       :..::::.:..:::.    ..  :. :.    . .: .:  .  : .   :    :.: :
NP_065 GVDIYPENLNSKKKFGADDKNEVKNKPAVP--KNSLHLDLEKRDLNGNFPKTNLKPGSPS
       60        70        80          90       100       110      

       120       130       140        150       160       170      
pF1KSD CIDQLPIKMDYGEELRSPITSLTPGESKT-TSPSSPEEDVMLGSLTFSVDYNFPKKALVV
        ...   :.     :..   :..:   :. :: .: :..  ::.: ::..::: .::.::
NP_065 DLENATPKL----FLEGEKESVSPESLKSSTSLTSEEKQEKLGTLFFSLEYNFERKAFVV
        120           130       140       150       160       170  

        180       190       200       210       220       230      
pF1KSD TIQEAHGLPVMDDQTQGSDPYIKMTILPDKRHRVKTRVLRKTLDPVFDETFTFYGIPYSQ
       .:.::.:::.::.:.. :::::::::::.:.:.::::::::::::.::::::::::::.:
NP_065 NIKEARGLPAMDEQSMTSDPYIKMTILPEKKHKVKTRVLRKTLDPAFDETFTFYGIPYTQ
            180       190       200       210       220       230  

        240       250       260       270       280       290      
pF1KSD LQDLVLHFLVLSFDRFSRDDVIGEVMVPLAGVDPSTGKVQLTRDIIKRNIQKCISRGELQ
       .:.:.::: .::::::::::.::::..::.:.. : ::. ..:.:::::..:  .:::: 
NP_065 IQELALHFTILSFDRFSRDDIIGEVLIPLSGIELSEGKMLMNREIIKRNVRKSSGRGELL
            240       250       260       270       280       290  

        300       310       320       330       340       350      
pF1KSD VSLSYQPVAQRMTVVVLKARHLPKMDITGLSGNPYVKVNVYYGRKRIAKKKTHVKKCTLN
       .:: :: ... .:::::::::::: :..::: .::::::.:...:::.:::::::::: :
NP_065 ISLCYQSTTNTLTVVVLKARHLPKSDVSGLS-DPYVKVNLYHAKKRISKKKTHVKKCTPN
            300       310       320        330       340       350 

        360       370       380       390       400       410      
pF1KSD PIFNESFIYDIPTDLLPDISIEFLVIDFDRTTKNEVVGRLILGAHSVTASGAEHWREVCE
        .::: :..::: . : :::.::::.: .: ..:::.:.:.::: .. ..:.:::.:.:.
NP_065 AVFNELFVFDIPCEGLEDISVEFLVLDSERGSRNEVIGQLVLGA-AAEGTGGEHWKEICD
             360       370       380       390        400       410

        420       430 
pF1KSD SPRKPVAKWHSLSEY
        ::. .:::: : . 
NP_065 YPRRQIAKWHVLCDG
              420     

>>XP_006723404 (OMIM: 600782) PREDICTED: synaptotagmin-5  (383 aa)
 initn: 737 init1: 253 opt: 815  Z-score: 749.5  bits: 147.6 E(85289): 5.2e-35
Smith-Waterman score: 815; 41.7% identity (68.0% similar) in 331 aa overlap (108-428:48-371)

        80        90       100       110       120       130       
pF1KSD VRRDKDGPGREGGRRNLLVDAAEAGLLSRDKDPRGPSSGSCIDQLPIKMDYGEELRSPIT
                                     :: : :   :   : :  .    .: .:..
XP_006 HGSWSSLLCVGLKGRLGWEWGTRVLECLCRKDSRTPPPCSRSPQ-PRGLHRPTRLPTPVA
        20        30        40        50        60         70      

       140            150           160       170       180        
pF1KSD SLTPG-----ESKTTSPSSPEEDVM----LGSLTFSVDYNFPKKALVVTIQEAHGLPVMD
       : :       :    .::.: ..:     :: : .:.::.: .  :.: : .: :: ..:
XP_006 SATAQVQPEVEELEPAPSGPGQQVADKHELGRLQYSLDYDFQSGQLLVGILQAMGLAALD
         80        90       100       110       120       130      

      190       200       210       220       230       240        
pF1KSD DQTQGSDPYIKMTILPDKRHRVKTRVLRKTLDPVFDETFTFYGIPYSQLQDLVLHFLVLS
           .::::... .:::::.: .:.: :.::.: : :::.:  .:: .:   :: . : .
XP_006 -LGGSSDPYVRVYLLPDKRRRYETKVHRQTLNPHFGETFAFK-VPYVELGGRVLVMAVYD
         140       150       160       170        180       190    

      250       260       270        280       290       300       
pF1KSD FDRFSRDDVIGEVMVPLAGVDPSTGK-VQLTRDIIKRNIQKCISRGELQVSLSYQPVAQR
       ::::::.:.:::: ::...::   :. ::  :..     ..  . :..  :: : :.: .
XP_006 FDRFSRNDAIGEVRVPMSSVD--LGRPVQAWRELQAAPREEQEKLGDICFSLRYVPTAGK
          200       210         220       230       240       250  

       310       320       330       340       350       360       
pF1KSD MTVVVLKARHLPKMDITGLSGNPYVKVNVYYGRKRIAKKKTHVKKCTLNPIFNESFIYDI
       .::.::.:..: :::. ::: .:::::..  : :.. :::: .:: :::: .::.: ...
XP_006 LTVIVLEAKNLKKMDVGGLS-DPYVKVHLLQGGKKVRKKKTTIKKNTLNPYYNEAFSFEV
            260       270        280       290       300       310 

       370       380       390       400       410       420       
pF1KSD PTDLLPDISIEFLVIDFDRTTKNEVVGRLILGAHSVTASGAEHWREVCESPRKPVAKWHS
       : : .  ...:. :.:.:.  :::..::. .:: .. ..: .:: ..  .::.:.:.:::
XP_006 PCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGA-AAGGAGLRHWADMLANPRRPIAQWHS
             320       330       340        350       360       370

       430          
pF1KSD LSEY         
       :            
XP_006 LRPPDRVRLLPAP
              380   

>>NP_001284703 (OMIM: 600782) synaptotagmin-5 isoform 2   (382 aa)
 initn: 613 init1: 253 opt: 811  Z-score: 746.0  bits: 146.9 E(85289): 8.2e-35
Smith-Waterman score: 811; 42.0% identity (67.9% similar) in 333 aa overlap (108-428:48-370)

        80        90       100       110       120       130       
pF1KSD VRRDKDGPGREGGRRNLLVDAAEAGLLSRDKDPRGPSSGSCIDQLPIKMDYGEELRSPIT
                                     :: : :   :   : :  .    .: .:..
NP_001 HGSWSSLLCVGLKGRLGWEWGTRVLECLCRKDSRTPPPCSRSPQ-PRGLHRPTRLPTPVA
        20        30        40        50        60         70      

       140            150           160       170       180        
pF1KSD SLTPG-----ESKTTSPSSPEEDVM----LGSLTFSVDYNFPKKALVVTIQEAHGLPVMD
       : :       :    .::.: ..:     :: : .:.::.: .  :.: : .: :: ..:
NP_001 SATAQVQPEVEELEPAPSGPGQQVADKHELGRLQYSLDYDFQSGQLLVGILQAMGLAALD
         80        90       100       110       120       130      

      190       200       210       220       230       240        
pF1KSD DQTQGSDPYIKMTILPDKRHRVKTRVLRKTLDPVFDETFTFYGIPYSQLQDLVLHFLVLS
           .::::... .:::::.: .:.: :.::.: : :::.:  .:: .:   :: . : .
NP_001 -LGGSSDPYVRVYLLPDKRRRYETKVHRQTLNPHFGETFAFK-VPYVELGGRVLVMAVYD
         140       150       160       170        180       190    

      250       260       270        280         290       300     
pF1KSD FDRFSRDDVIGEVMVPLAGVDPSTGK-VQLTRDI--IKRNIQKCISRGELQVSLSYQPVA
       ::::::.:.:::: ::...::   :. ::  :..    :. .:    :..  :: : :.:
NP_001 FDRFSRNDAIGEVRVPMSSVD--LGRPVQAWRELQAAPREEEKL---GDICFSLRYVPTA
          200       210         220       230          240         

         310       320       330       340       350       360     
pF1KSD QRMTVVVLKARHLPKMDITGLSGNPYVKVNVYYGRKRIAKKKTHVKKCTLNPIFNESFIY
        ..::.::.:..: :::. ::: .:::::..  : :.. :::: .:: :::: .::.: .
NP_001 GKLTVIVLEAKNLKKMDVGGLS-DPYVKVHLLQGGKKVRKKKTTIKKNTLNPYYNEAFSF
     250       260       270        280       290       300        

         370       380       390       400       410       420     
pF1KSD DIPTDLLPDISIEFLVIDFDRTTKNEVVGRLILGAHSVTASGAEHWREVCESPRKPVAKW
       ..: : .  ...:. :.:.:.  :::..::. .:: .. ..: .:: ..  .::.:.:.:
NP_001 EVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGA-AAGGAGLRHWADMLANPRRPIAQW
      310       320       330       340        350       360       

         430          
pF1KSD HSLSEY         
       :::            
NP_001 HSLRPPDRVRLLPAP
       370       380  

>>XP_016882665 (OMIM: 600782) PREDICTED: synaptotagmin-5  (386 aa)
 initn: 666 init1: 253 opt: 797  Z-score: 733.3  bits: 144.6 E(85289): 4.2e-34
Smith-Waterman score: 797; 43.0% identity (71.2% similar) in 302 aa overlap (133-428:79-374)

            110       120       130       140        150           
pF1KSD LLSRDKDPRGPSSGSCIDQLPIKMDYGEELRSPITSLTPG-ESKTTSPSSPEEDVM----
                                     .: : .. :  :    .::.: ..:     
XP_016 CLYRKSCRRRTGKKSQAQAQVHLQEVKGLGQSYIDKVQPEVEELEPAPSGPGQQVADKHE
       50        60        70        80        90       100        

       160       170       180       190       200       210       
pF1KSD LGSLTFSVDYNFPKKALVVTIQEAHGLPVMDDQTQGSDPYIKMTILPDKRHRVKTRVLRK
       :: : .:.::.: .  :.: : .: :: ..:    .::::... .:::::.: .:.: :.
XP_016 LGRLQYSLDYDFQSGQLLVGILQAMGLAALD-LGGSSDPYVRVYLLPDKRRRYETKVHRQ
      110       120       130        140       150       160       

       220       230       240       250       260       270       
pF1KSD TLDPVFDETFTFYGIPYSQLQDLVLHFLVLSFDRFSRDDVIGEVMVPLAGVDPSTGK-VQ
       ::.: : :::.:  .:: .:   :: . : .::::::.:.:::: ::...::   :. ::
XP_016 TLNPHFGETFAFK-VPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVD--LGRPVQ
       170       180        190       200       210         220    

        280       290       300       310       320       330      
pF1KSD LTRDIIKRNIQKCISRGELQVSLSYQPVAQRMTVVVLKARHLPKMDITGLSGNPYVKVNV
         :..     ..  . :..  :: : :.: ..::.::.:..: :::. ::: .:::::..
XP_016 AWRELQAAPREEQEKLGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLS-DPYVKVHL
          230       240       250       260       270        280   

        340       350       360       370       380       390      
pF1KSD YYGRKRIAKKKTHVKKCTLNPIFNESFIYDIPTDLLPDISIEFLVIDFDRTTKNEVVGRL
         : :.. :::: .:: :::: .::.: ...: : .  ...:. :.:.:.  :::..::.
XP_016 LQGGKKVRKKKTTIKKNTLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRV
           290       300       310       320       330       340   

        400       410       420       430          
pF1KSD ILGAHSVTASGAEHWREVCESPRKPVAKWHSLSEY         
        .:: .. ..: .:: ..  .::.:.:.::::            
XP_016 AVGA-AAGGAGLRHWADMLANPRRPIAQWHSLRPPDRVRLLPAP
            350       360       370       380      

>>NP_003171 (OMIM: 600782) synaptotagmin-5 isoform 1 [Ho  (386 aa)
 initn: 666 init1: 253 opt: 797  Z-score: 733.3  bits: 144.6 E(85289): 4.2e-34
Smith-Waterman score: 797; 43.0% identity (71.2% similar) in 302 aa overlap (133-428:79-374)

            110       120       130       140        150           
pF1KSD LLSRDKDPRGPSSGSCIDQLPIKMDYGEELRSPITSLTPG-ESKTTSPSSPEEDVM----
                                     .: : .. :  :    .::.: ..:     
NP_003 CLYRKSCRRRTGKKSQAQAQVHLQEVKGLGQSYIDKVQPEVEELEPAPSGPGQQVADKHE
       50        60        70        80        90       100        

       160       170       180       190       200       210       
pF1KSD LGSLTFSVDYNFPKKALVVTIQEAHGLPVMDDQTQGSDPYIKMTILPDKRHRVKTRVLRK
       :: : .:.::.: .  :.: : .: :: ..:    .::::... .:::::.: .:.: :.
NP_003 LGRLQYSLDYDFQSGQLLVGILQAMGLAALD-LGGSSDPYVRVYLLPDKRRRYETKVHRQ
      110       120       130        140       150       160       

       220       230       240       250       260       270       
pF1KSD TLDPVFDETFTFYGIPYSQLQDLVLHFLVLSFDRFSRDDVIGEVMVPLAGVDPSTGK-VQ
       ::.: : :::.:  .:: .:   :: . : .::::::.:.:::: ::...::   :. ::
NP_003 TLNPHFGETFAFK-VPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVD--LGRPVQ
       170       180        190       200       210         220    

        280       290       300       310       320       330      
pF1KSD LTRDIIKRNIQKCISRGELQVSLSYQPVAQRMTVVVLKARHLPKMDITGLSGNPYVKVNV
         :..     ..  . :..  :: : :.: ..::.::.:..: :::. ::: .:::::..
NP_003 AWRELQAAPREEQEKLGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLS-DPYVKVHL
          230       240       250       260       270        280   

        340       350       360       370       380       390      
pF1KSD YYGRKRIAKKKTHVKKCTLNPIFNESFIYDIPTDLLPDISIEFLVIDFDRTTKNEVVGRL
         : :.. :::: .:: :::: .::.: ...: : .  ...:. :.:.:.  :::..::.
NP_003 LQGGKKVRKKKTTIKKNTLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRV
           290       300       310       320       330       340   

        400       410       420       430          
pF1KSD ILGAHSVTASGAEHWREVCESPRKPVAKWHSLSEY         
        .:: .. ..: .:: ..  .::.:.:.::::            
NP_003 AVGA-AAGGAGLRHWADMLANPRRPIAQWHSLRPPDRVRLLPAP
            350       360       370       380      

>>XP_006723402 (OMIM: 600782) PREDICTED: synaptotagmin-5  (386 aa)
 initn: 666 init1: 253 opt: 797  Z-score: 733.3  bits: 144.6 E(85289): 4.2e-34
Smith-Waterman score: 797; 43.0% identity (71.2% similar) in 302 aa overlap (133-428:79-374)

            110       120       130       140        150           
pF1KSD LLSRDKDPRGPSSGSCIDQLPIKMDYGEELRSPITSLTPG-ESKTTSPSSPEEDVM----
                                     .: : .. :  :    .::.: ..:     
XP_006 CLYRKSCRRRTGKKSQAQAQVHLQEVKGLGQSYIDKVQPEVEELEPAPSGPGQQVADKHE
       50        60        70        80        90       100        

       160       170       180       190       200       210       
pF1KSD LGSLTFSVDYNFPKKALVVTIQEAHGLPVMDDQTQGSDPYIKMTILPDKRHRVKTRVLRK
       :: : .:.::.: .  :.: : .: :: ..:    .::::... .:::::.: .:.: :.
XP_006 LGRLQYSLDYDFQSGQLLVGILQAMGLAALD-LGGSSDPYVRVYLLPDKRRRYETKVHRQ
      110       120       130        140       150       160       

       220       230       240       250       260       270       
pF1KSD TLDPVFDETFTFYGIPYSQLQDLVLHFLVLSFDRFSRDDVIGEVMVPLAGVDPSTGK-VQ
       ::.: : :::.:  .:: .:   :: . : .::::::.:.:::: ::...::   :. ::
XP_006 TLNPHFGETFAFK-VPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVD--LGRPVQ
       170       180        190       200       210         220    

        280       290       300       310       320       330      
pF1KSD LTRDIIKRNIQKCISRGELQVSLSYQPVAQRMTVVVLKARHLPKMDITGLSGNPYVKVNV
         :..     ..  . :..  :: : :.: ..::.::.:..: :::. ::: .:::::..
XP_006 AWRELQAAPREEQEKLGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLS-DPYVKVHL
          230       240       250       260       270        280   

        340       350       360       370       380       390      
pF1KSD YYGRKRIAKKKTHVKKCTLNPIFNESFIYDIPTDLLPDISIEFLVIDFDRTTKNEVVGRL
         : :.. :::: .:: :::: .::.: ...: : .  ...:. :.:.:.  :::..::.
XP_006 LQGGKKVRKKKTTIKKNTLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRV
           290       300       310       320       330       340   

        400       410       420       430          
pF1KSD ILGAHSVTASGAEHWREVCESPRKPVAKWHSLSEY         
        .:: .. ..: .:: ..  .::.:.:.::::            
XP_006 AVGA-AAGGAGLRHWADMLANPRRPIAQWHSLRPPDRVRLLPAP
            350       360       370       380      

>>XP_016882664 (OMIM: 600782) PREDICTED: synaptotagmin-5  (386 aa)
 initn: 666 init1: 253 opt: 797  Z-score: 733.3  bits: 144.6 E(85289): 4.2e-34
Smith-Waterman score: 797; 43.0% identity (71.2% similar) in 302 aa overlap (133-428:79-374)

            110       120       130       140        150           
pF1KSD LLSRDKDPRGPSSGSCIDQLPIKMDYGEELRSPITSLTPG-ESKTTSPSSPEEDVM----
                                     .: : .. :  :    .::.: ..:     
XP_016 CLYRKSCRRRTGKKSQAQAQVHLQEVKGLGQSYIDKVQPEVEELEPAPSGPGQQVADKHE
       50        60        70        80        90       100        

       160       170       180       190       200       210       
pF1KSD LGSLTFSVDYNFPKKALVVTIQEAHGLPVMDDQTQGSDPYIKMTILPDKRHRVKTRVLRK
       :: : .:.::.: .  :.: : .: :: ..:    .::::... .:::::.: .:.: :.
XP_016 LGRLQYSLDYDFQSGQLLVGILQAMGLAALD-LGGSSDPYVRVYLLPDKRRRYETKVHRQ
      110       120       130        140       150       160       

       220       230       240       250       260       270       
pF1KSD TLDPVFDETFTFYGIPYSQLQDLVLHFLVLSFDRFSRDDVIGEVMVPLAGVDPSTGK-VQ
       ::.: : :::.:  .:: .:   :: . : .::::::.:.:::: ::...::   :. ::
XP_016 TLNPHFGETFAFK-VPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVD--LGRPVQ
       170       180        190       200       210         220    

        280       290       300       310       320       330      
pF1KSD LTRDIIKRNIQKCISRGELQVSLSYQPVAQRMTVVVLKARHLPKMDITGLSGNPYVKVNV
         :..     ..  . :..  :: : :.: ..::.::.:..: :::. ::: .:::::..
XP_016 AWRELQAAPREEQEKLGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLS-DPYVKVHL
          230       240       250       260       270        280   

        340       350       360       370       380       390      
pF1KSD YYGRKRIAKKKTHVKKCTLNPIFNESFIYDIPTDLLPDISIEFLVIDFDRTTKNEVVGRL
         : :.. :::: .:: :::: .::.: ...: : .  ...:. :.:.:.  :::..::.
XP_016 LQGGKKVRKKKTTIKKNTLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRV
           290       300       310       320       330       340   

        400       410       420       430          
pF1KSD ILGAHSVTASGAEHWREVCESPRKPVAKWHSLSEY         
        .:: .. ..: .:: ..  .::.:.:.::::            
XP_016 AVGA-AAGGAGLRHWADMLANPRRPIAQWHSLRPPDRVRLLPAP
            350       360       370       380      




431 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Wed Nov  2 23:50:19 2016 done: Wed Nov  2 23:50:21 2016
 Total Scan time:  7.350 Total Display time:  0.040

Function used was FASTA [36.3.4 Apr, 2011]
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