Result of FASTA (omim) for pF1KSDA0064
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KSDA0064, 470 aa
  1>>>pF1KSDA0064 470 - 470 aa - 470 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.7208+/-0.000352; mu= 16.1155+/- 0.022
 mean_var=79.7522+/-15.959, 0's: 0 Z-trim(114.9): 48  B-trim: 424 in 2/56
 Lambda= 0.143616
 statistics sampled from 24928 (24975) to 24928 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.675), E-opt: 0.2 (0.293), width:  16
 Scan time:  7.580

The best scores are:                                      opt bits E(85289)
NP_055563 (OMIM: 605963) sorting nexin-17 isoform  ( 470) 3046 640.8 2.3e-183
NP_001253990 (OMIM: 605963) sorting nexin-17 isofo ( 450) 2908 612.2  9e-175
NP_001253988 (OMIM: 605963) sorting nexin-17 isofo ( 458) 2747 578.9  1e-164
NP_001253989 (OMIM: 605963) sorting nexin-17 isofo ( 445) 2734 576.2 6.4e-164
XP_011531505 (OMIM: 605963) PREDICTED: sorting nex ( 256) 1667 355.0 1.4e-97
XP_016860894 (OMIM: 605963) PREDICTED: sorting nex ( 256) 1667 355.0 1.4e-97
XP_005245567 (OMIM: 611541) PREDICTED: sorting nex ( 438)  406 93.8   1e-18
NP_112180 (OMIM: 611541) sorting nexin-27 isoform  ( 528)  406 93.9 1.2e-18
NP_001317652 (OMIM: 611541) sorting nexin-27 isofo ( 541)  406 93.9 1.2e-18
XP_016857906 (OMIM: 611541) PREDICTED: sorting nex ( 407)  390 90.5 9.4e-18
XP_011508327 (OMIM: 611541) PREDICTED: sorting nex ( 420)  390 90.5 9.6e-18
XP_011508326 (OMIM: 611541) PREDICTED: sorting nex ( 440)  388 90.1 1.3e-17
XP_005245568 (OMIM: 611541) PREDICTED: sorting nex ( 342)  367 85.7 2.2e-16
XP_011508328 (OMIM: 611541) PREDICTED: sorting nex ( 419)  321 76.2 1.9e-13


>>NP_055563 (OMIM: 605963) sorting nexin-17 isoform 1 [H  (470 aa)
 initn: 3046 init1: 3046 opt: 3046  Z-score: 3412.9  bits: 640.8 E(85289): 2.3e-183
Smith-Waterman score: 3046; 100.0% identity (100.0% similar) in 470 aa overlap (1-470:1-470)

               10        20        30        40        50        60
pF1KSD MHFSIPETESRSGDSGGSAYVAYNIHVNGVLHCRVRYSQLLGLHEQLRKEYGANVLPAFP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MHFSIPETESRSGDSGGSAYVAYNIHVNGVLHCRVRYSQLLGLHEQLRKEYGANVLPAFP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD PKKLFSLTPAEVEQRREQLEKYMQAVRQDPLLGSSETFNSFLRRAQQETQQVPTEEVSLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PKKLFSLTPAEVEQRREQLEKYMQAVRQDPLLGSSETFNSFLRRAQQETQQVPTEEVSLE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD VLLSNGQKVLVNVLTSDQTEDVLEAVAAKLDLPDDLIGYFSLFLVREKEDGAFSFVRKLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VLLSNGQKVLVNVLTSDQTEDVLEAVAAKLDLPDDLIGYFSLFLVREKEDGAFSFVRKLQ
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD EFELPYVSVTSLRSQEYKIVLRKSYWDSAYDDDVMENRVGLNLLYAQTVSDIERGWILVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EFELPYVSVTSLRSQEYKIVLRKSYWDSAYDDDVMENRVGLNLLYAQTVSDIERGWILVT
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD KEQHRQLKSLQEKVSKKEFLRLAQTLRHYGYLRFDACVADFPEKDCPVVVSAGNSELSLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KEQHRQLKSLQEKVSKKEFLRLAQTLRHYGYLRFDACVADFPEKDCPVVVSAGNSELSLQ
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD LRLPGQQLREGSFRVTRMRCWRVTSSVPLPSGSTSSPGRGRGEVRLELAFEYLMSKDRLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LRLPGQQLREGSFRVTRMRCWRVTSSVPLPSGSTSSPGRGRGEVRLELAFEYLMSKDRLQ
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD WVTITSPQAIMMSICLQSMVDELMVKKSGGSIRKMLRRRVGGTLRRSDSQQAVKSPPLLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 WVTITSPQAIMMSICLQSMVDELMVKKSGGSIRKMLRRRVGGTLRRSDSQQAVKSPPLLE
              370       380       390       400       410       420

              430       440       450       460       470
pF1KSD SPDATRESMVKLSSKLSAVSLRGIGSPSTDASASDVHGNFAFEGIGDEDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SPDATRESMVKLSSKLSAVSLRGIGSPSTDASASDVHGNFAFEGIGDEDL
              430       440       450       460       470

>>NP_001253990 (OMIM: 605963) sorting nexin-17 isoform 4  (450 aa)
 initn: 2908 init1: 2908 opt: 2908  Z-score: 3258.7  bits: 612.2 E(85289): 9e-175
Smith-Waterman score: 2908; 99.8% identity (100.0% similar) in 450 aa overlap (21-470:1-450)

               10        20        30        40        50        60
pF1KSD MHFSIPETESRSGDSGGSAYVAYNIHVNGVLHCRVRYSQLLGLHEQLRKEYGANVLPAFP
                           .:::::::::::::::::::::::::::::::::::::::
NP_001                     MAYNIHVNGVLHCRVRYSQLLGLHEQLRKEYGANVLPAFP
                                   10        20        30        40

               70        80        90       100       110       120
pF1KSD PKKLFSLTPAEVEQRREQLEKYMQAVRQDPLLGSSETFNSFLRRAQQETQQVPTEEVSLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKKLFSLTPAEVEQRREQLEKYMQAVRQDPLLGSSETFNSFLRRAQQETQQVPTEEVSLE
               50        60        70        80        90       100

              130       140       150       160       170       180
pF1KSD VLLSNGQKVLVNVLTSDQTEDVLEAVAAKLDLPDDLIGYFSLFLVREKEDGAFSFVRKLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLLSNGQKVLVNVLTSDQTEDVLEAVAAKLDLPDDLIGYFSLFLVREKEDGAFSFVRKLQ
              110       120       130       140       150       160

              190       200       210       220       230       240
pF1KSD EFELPYVSVTSLRSQEYKIVLRKSYWDSAYDDDVMENRVGLNLLYAQTVSDIERGWILVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EFELPYVSVTSLRSQEYKIVLRKSYWDSAYDDDVMENRVGLNLLYAQTVSDIERGWILVT
              170       180       190       200       210       220

              250       260       270       280       290       300
pF1KSD KEQHRQLKSLQEKVSKKEFLRLAQTLRHYGYLRFDACVADFPEKDCPVVVSAGNSELSLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KEQHRQLKSLQEKVSKKEFLRLAQTLRHYGYLRFDACVADFPEKDCPVVVSAGNSELSLQ
              230       240       250       260       270       280

              310       320       330       340       350       360
pF1KSD LRLPGQQLREGSFRVTRMRCWRVTSSVPLPSGSTSSPGRGRGEVRLELAFEYLMSKDRLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRLPGQQLREGSFRVTRMRCWRVTSSVPLPSGSTSSPGRGRGEVRLELAFEYLMSKDRLQ
              290       300       310       320       330       340

              370       380       390       400       410       420
pF1KSD WVTITSPQAIMMSICLQSMVDELMVKKSGGSIRKMLRRRVGGTLRRSDSQQAVKSPPLLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WVTITSPQAIMMSICLQSMVDELMVKKSGGSIRKMLRRRVGGTLRRSDSQQAVKSPPLLE
              350       360       370       380       390       400

              430       440       450       460       470
pF1KSD SPDATRESMVKLSSKLSAVSLRGIGSPSTDASASDVHGNFAFEGIGDEDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPDATRESMVKLSSKLSAVSLRGIGSPSTDASASDVHGNFAFEGIGDEDL
              410       420       430       440       450

>>NP_001253988 (OMIM: 605963) sorting nexin-17 isoform 2  (458 aa)
 initn: 2747 init1: 2747 opt: 2747  Z-score: 3078.3  bits: 578.9 E(85289): 1e-164
Smith-Waterman score: 2934; 97.4% identity (97.4% similar) in 470 aa overlap (1-470:1-458)

               10        20        30        40        50        60
pF1KSD MHFSIPETESRSGDSGGSAYVAYNIHVNGVLHCRVRYSQLLGLHEQLRKEYGANVLPAFP
       ::::::::::::::::::::::::::::::::::            ::::::::::::::
NP_001 MHFSIPETESRSGDSGGSAYVAYNIHVNGVLHCR------------LRKEYGANVLPAFP
               10        20        30                    40        

               70        80        90       100       110       120
pF1KSD PKKLFSLTPAEVEQRREQLEKYMQAVRQDPLLGSSETFNSFLRRAQQETQQVPTEEVSLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKKLFSLTPAEVEQRREQLEKYMQAVRQDPLLGSSETFNSFLRRAQQETQQVPTEEVSLE
       50        60        70        80        90       100        

              130       140       150       160       170       180
pF1KSD VLLSNGQKVLVNVLTSDQTEDVLEAVAAKLDLPDDLIGYFSLFLVREKEDGAFSFVRKLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLLSNGQKVLVNVLTSDQTEDVLEAVAAKLDLPDDLIGYFSLFLVREKEDGAFSFVRKLQ
      110       120       130       140       150       160        

              190       200       210       220       230       240
pF1KSD EFELPYVSVTSLRSQEYKIVLRKSYWDSAYDDDVMENRVGLNLLYAQTVSDIERGWILVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EFELPYVSVTSLRSQEYKIVLRKSYWDSAYDDDVMENRVGLNLLYAQTVSDIERGWILVT
      170       180       190       200       210       220        

              250       260       270       280       290       300
pF1KSD KEQHRQLKSLQEKVSKKEFLRLAQTLRHYGYLRFDACVADFPEKDCPVVVSAGNSELSLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KEQHRQLKSLQEKVSKKEFLRLAQTLRHYGYLRFDACVADFPEKDCPVVVSAGNSELSLQ
      230       240       250       260       270       280        

              310       320       330       340       350       360
pF1KSD LRLPGQQLREGSFRVTRMRCWRVTSSVPLPSGSTSSPGRGRGEVRLELAFEYLMSKDRLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRLPGQQLREGSFRVTRMRCWRVTSSVPLPSGSTSSPGRGRGEVRLELAFEYLMSKDRLQ
      290       300       310       320       330       340        

              370       380       390       400       410       420
pF1KSD WVTITSPQAIMMSICLQSMVDELMVKKSGGSIRKMLRRRVGGTLRRSDSQQAVKSPPLLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WVTITSPQAIMMSICLQSMVDELMVKKSGGSIRKMLRRRVGGTLRRSDSQQAVKSPPLLE
      350       360       370       380       390       400        

              430       440       450       460       470
pF1KSD SPDATRESMVKLSSKLSAVSLRGIGSPSTDASASDVHGNFAFEGIGDEDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPDATRESMVKLSSKLSAVSLRGIGSPSTDASASDVHGNFAFEGIGDEDL
      410       420       430       440       450        

>>NP_001253989 (OMIM: 605963) sorting nexin-17 isoform 3  (445 aa)
 initn: 2859 init1: 2734 opt: 2734  Z-score: 3063.9  bits: 576.2 E(85289): 6.4e-164
Smith-Waterman score: 2813; 94.7% identity (94.7% similar) in 470 aa overlap (1-470:1-445)

               10        20        30        40        50        60
pF1KSD MHFSIPETESRSGDSGGSAYVAYNIHVNGVLHCRVRYSQLLGLHEQLRKEYGANVLPAFP
       :::::::::::::::::::::                         ::::::::::::::
NP_001 MHFSIPETESRSGDSGGSAYV-------------------------LRKEYGANVLPAFP
               10        20                                 30     

               70        80        90       100       110       120
pF1KSD PKKLFSLTPAEVEQRREQLEKYMQAVRQDPLLGSSETFNSFLRRAQQETQQVPTEEVSLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKKLFSLTPAEVEQRREQLEKYMQAVRQDPLLGSSETFNSFLRRAQQETQQVPTEEVSLE
          40        50        60        70        80        90     

              130       140       150       160       170       180
pF1KSD VLLSNGQKVLVNVLTSDQTEDVLEAVAAKLDLPDDLIGYFSLFLVREKEDGAFSFVRKLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLLSNGQKVLVNVLTSDQTEDVLEAVAAKLDLPDDLIGYFSLFLVREKEDGAFSFVRKLQ
         100       110       120       130       140       150     

              190       200       210       220       230       240
pF1KSD EFELPYVSVTSLRSQEYKIVLRKSYWDSAYDDDVMENRVGLNLLYAQTVSDIERGWILVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EFELPYVSVTSLRSQEYKIVLRKSYWDSAYDDDVMENRVGLNLLYAQTVSDIERGWILVT
         160       170       180       190       200       210     

              250       260       270       280       290       300
pF1KSD KEQHRQLKSLQEKVSKKEFLRLAQTLRHYGYLRFDACVADFPEKDCPVVVSAGNSELSLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KEQHRQLKSLQEKVSKKEFLRLAQTLRHYGYLRFDACVADFPEKDCPVVVSAGNSELSLQ
         220       230       240       250       260       270     

              310       320       330       340       350       360
pF1KSD LRLPGQQLREGSFRVTRMRCWRVTSSVPLPSGSTSSPGRGRGEVRLELAFEYLMSKDRLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRLPGQQLREGSFRVTRMRCWRVTSSVPLPSGSTSSPGRGRGEVRLELAFEYLMSKDRLQ
         280       290       300       310       320       330     

              370       380       390       400       410       420
pF1KSD WVTITSPQAIMMSICLQSMVDELMVKKSGGSIRKMLRRRVGGTLRRSDSQQAVKSPPLLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WVTITSPQAIMMSICLQSMVDELMVKKSGGSIRKMLRRRVGGTLRRSDSQQAVKSPPLLE
         340       350       360       370       380       390     

              430       440       450       460       470
pF1KSD SPDATRESMVKLSSKLSAVSLRGIGSPSTDASASDVHGNFAFEGIGDEDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPDATRESMVKLSSKLSAVSLRGIGSPSTDASASDVHGNFAFEGIGDEDL
         400       410       420       430       440     

>>XP_011531505 (OMIM: 605963) PREDICTED: sorting nexin-1  (256 aa)
 initn: 1667 init1: 1667 opt: 1667  Z-score: 1872.7  bits: 355.0 E(85289): 1.4e-97
Smith-Waterman score: 1667; 100.0% identity (100.0% similar) in 256 aa overlap (215-470:1-256)

          190       200       210       220       230       240    
pF1KSD PYVSVTSLRSQEYKIVLRKSYWDSAYDDDVMENRVGLNLLYAQTVSDIERGWILVTKEQH
                                     ::::::::::::::::::::::::::::::
XP_011                               MENRVGLNLLYAQTVSDIERGWILVTKEQH
                                             10        20        30

          250       260       270       280       290       300    
pF1KSD RQLKSLQEKVSKKEFLRLAQTLRHYGYLRFDACVADFPEKDCPVVVSAGNSELSLQLRLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RQLKSLQEKVSKKEFLRLAQTLRHYGYLRFDACVADFPEKDCPVVVSAGNSELSLQLRLP
               40        50        60        70        80        90

          310       320       330       340       350       360    
pF1KSD GQQLREGSFRVTRMRCWRVTSSVPLPSGSTSSPGRGRGEVRLELAFEYLMSKDRLQWVTI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GQQLREGSFRVTRMRCWRVTSSVPLPSGSTSSPGRGRGEVRLELAFEYLMSKDRLQWVTI
              100       110       120       130       140       150

          370       380       390       400       410       420    
pF1KSD TSPQAIMMSICLQSMVDELMVKKSGGSIRKMLRRRVGGTLRRSDSQQAVKSPPLLESPDA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSPQAIMMSICLQSMVDELMVKKSGGSIRKMLRRRVGGTLRRSDSQQAVKSPPLLESPDA
              160       170       180       190       200       210

          430       440       450       460       470
pF1KSD TRESMVKLSSKLSAVSLRGIGSPSTDASASDVHGNFAFEGIGDEDL
       ::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRESMVKLSSKLSAVSLRGIGSPSTDASASDVHGNFAFEGIGDEDL
              220       230       240       250      

>>XP_016860894 (OMIM: 605963) PREDICTED: sorting nexin-1  (256 aa)
 initn: 1667 init1: 1667 opt: 1667  Z-score: 1872.7  bits: 355.0 E(85289): 1.4e-97
Smith-Waterman score: 1667; 100.0% identity (100.0% similar) in 256 aa overlap (215-470:1-256)

          190       200       210       220       230       240    
pF1KSD PYVSVTSLRSQEYKIVLRKSYWDSAYDDDVMENRVGLNLLYAQTVSDIERGWILVTKEQH
                                     ::::::::::::::::::::::::::::::
XP_016                               MENRVGLNLLYAQTVSDIERGWILVTKEQH
                                             10        20        30

          250       260       270       280       290       300    
pF1KSD RQLKSLQEKVSKKEFLRLAQTLRHYGYLRFDACVADFPEKDCPVVVSAGNSELSLQLRLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQLKSLQEKVSKKEFLRLAQTLRHYGYLRFDACVADFPEKDCPVVVSAGNSELSLQLRLP
               40        50        60        70        80        90

          310       320       330       340       350       360    
pF1KSD GQQLREGSFRVTRMRCWRVTSSVPLPSGSTSSPGRGRGEVRLELAFEYLMSKDRLQWVTI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GQQLREGSFRVTRMRCWRVTSSVPLPSGSTSSPGRGRGEVRLELAFEYLMSKDRLQWVTI
              100       110       120       130       140       150

          370       380       390       400       410       420    
pF1KSD TSPQAIMMSICLQSMVDELMVKKSGGSIRKMLRRRVGGTLRRSDSQQAVKSPPLLESPDA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSPQAIMMSICLQSMVDELMVKKSGGSIRKMLRRRVGGTLRRSDSQQAVKSPPLLESPDA
              160       170       180       190       200       210

          430       440       450       460       470
pF1KSD TRESMVKLSSKLSAVSLRGIGSPSTDASASDVHGNFAFEGIGDEDL
       ::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRESMVKLSSKLSAVSLRGIGSPSTDASASDVHGNFAFEGIGDEDL
              220       230       240       250      

>>XP_005245567 (OMIM: 611541) PREDICTED: sorting nexin-2  (438 aa)
 initn: 269 init1: 174 opt: 406  Z-score: 457.2  bits: 93.8 E(85289): 1e-18
Smith-Waterman score: 438; 25.8% identity (57.9% similar) in 399 aa overlap (4-397:63-430)

                                          10        20        30   
pF1KSD                            MHFSIPETESRSGDSGGSAYVAYNIHVNGVLHC
                                     :.:.   .  ...:  .:.::... :   :
XP_005 PPHEADNLDPSDDSLGQSFYDYTEKQAVPISVPR--YKHVEQNGEKFVVYNVYMAGRQLC
             40        50        60          70        80        90

            40        50        60        70        80        90   
pF1KSD RVRYSQLLGLHEQLRKEYGANVLPAFPPKKLFSLTPAEVEQRREQLEKYMQAVRQDPLLG
         :: ..  ::..:..:..  ..: .: :  :::.  ... ::. ::.:.. : .  ..:
XP_005 SKRYREFAILHQNLKREFANFTFPRLPGKWPFSLSEQQLDARRRGLEEYLEKVCSIRVIG
              100       110       120       130       140       150

           100       110       120       130       140       150   
pF1KSD SSETFNSFLRRAQQETQQVPTEEVSLEVLLSNGQKVLVNVLTSDQTEDVLEAVAAKLDLP
        :. .. :: ..... . :   .: :.: : .:  : : :  .. :..: .:.:::. . 
XP_005 ESDIMQEFLSESDENYNGVS--DVELRVALPDGTTVTVRVKKNSTTDQVYQAIAAKVGMD
              160       170         180       190       200        

           160       170       180        190       200       210  
pF1KSD DDLIGYFSLFLVREKEDGAFSFVRKLQEFELPY-VSVTSLRSQEYKIVLRKSYWDSAYDD
       .  ..::.::     :  . ::::::   :.:. . . .  :      :    :  . ..
XP_005 STTVNYFALF-----EVISHSFVRKLAPNEFPHKLYIQNYTSAVPGTCLTIRKWLFTTEE
      210            220       230       240       250       260   

              220       230       240       250       260       270
pF1KSD DVM--ENRVGLNLLYAQTVSDIERGWILVTKEQHRQLKSLQEKVSKKEFLRLAQTLRHYG
       ...  .: .... .. :.:.:...:.: . .:.  ::..: :. .   .: . .: . :.
XP_005 EILLNDNDLAVTYFFHQAVDDVKKGYIKA-EEKSYQLQKLYEQRKMVMYLNMLRTCEGYN
           270       280       290        300       310       320  

              280       290       300       310         320        
pF1KSD YLRFDACVADFPEKDCPVVVSAGNSELSLQLRLPGQQLREG--SFRVTRMRCWRVTSSVP
        . :  :. :  .:   :... . ....:.      ::..   .:.  .:. :       
XP_005 EIIFPHCACDSRRKG-HVITAISITHFKLHACTEEGQLENQVIAFEWDEMQRW-------
            330        340       350       360       370           

      330       340       350       360       370       380        
pF1KSD LPSGSTSSPGRGRGEVRLELAFEYLMSKDRLQWVTITSPQAIMMSICLQSMVDELMVKKS
           .:.  :       . . :::  .. . .:: : .:   .:  :.. .  ::  .: 
XP_005 ----DTDEEG-------MAFCFEYARGEKKPRWVKIFTPYFNYMHECFERVFCELKWRKE
              380              390       400       410       420   

      390       400       410       420       430       440        
pF1KSD GGSIRKMLRRRVGGTLRRSDSQQAVKSPPLLESPDATRESMVKLSSKLSAVSLRGIGSPS
         .: .: :                                                   
XP_005 --NIFQMARSQQRDVAT                                           
             430                                                   

>>NP_112180 (OMIM: 611541) sorting nexin-27 isoform 2 [H  (528 aa)
 initn: 269 init1: 174 opt: 406  Z-score: 456.0  bits: 93.9 E(85289): 1.2e-18
Smith-Waterman score: 436; 25.7% identity (58.1% similar) in 389 aa overlap (4-387:166-525)

                                          10        20        30   
pF1KSD                            MHFSIPETESRSGDSGGSAYVAYNIHVNGVLHC
                                     :.:.   .  ...:  .:.::... :   :
NP_112 PPHEADNLDPSDDSLGQSFYDYTEKQAVPISVPR--YKHVEQNGEKFVVYNVYMAGRQLC
         140       150       160         170       180       190   

            40        50        60        70        80        90   
pF1KSD RVRYSQLLGLHEQLRKEYGANVLPAFPPKKLFSLTPAEVEQRREQLEKYMQAVRQDPLLG
         :: ..  ::..:..:..  ..: .: :  :::.  ... ::. ::.:.. : .  ..:
NP_112 SKRYREFAILHQNLKREFANFTFPRLPGKWPFSLSEQQLDARRRGLEEYLEKVCSIRVIG
           200       210       220       230       240       250   

           100       110       120       130       140       150   
pF1KSD SSETFNSFLRRAQQETQQVPTEEVSLEVLLSNGQKVLVNVLTSDQTEDVLEAVAAKLDLP
        :. .. :: ..... . :   .: :.: : .:  : : :  .. :..: .:.:::. . 
NP_112 ESDIMQEFLSESDENYNGV--SDVELRVALPDGTTVTVRVKKNSTTDQVYQAIAAKVGMD
           260       270         280       290       300       310 

           160       170       180        190       200       210  
pF1KSD DDLIGYFSLFLVREKEDGAFSFVRKLQEFELPY-VSVTSLRSQEYKIVLRKSYWDSAYDD
       .  ..::.:: :      . ::::::   :.:. . . .  :      :    :  . ..
NP_112 STTVNYFALFEVI-----SHSFVRKLAPNEFPHKLYIQNYTSAVPGTCLTIRKWLFTTEE
             320            330       340       350       360      

              220       230       240       250       260       270
pF1KSD DVM--ENRVGLNLLYAQTVSDIERGWILVTKEQHRQLKSLQEKVSKKEFLRLAQTLRHYG
       ...  .: .... .. :.:.:...:.: . .:.  ::..: :. .   .: . .: . :.
NP_112 EILLNDNDLAVTYFFHQAVDDVKKGYIKA-EEKSYQLQKLYEQRKMVMYLNMLRTCEGYN
        370       380       390        400       410       420     

              280       290       300       310         320        
pF1KSD YLRFDACVADFPEKDCPVVVSAGNSELSLQLRLPGQQLREG--SFRVTRMRCWRVTSSVP
        . :  :. :  .:   :... . ....:.      ::..   .:.  .:. :       
NP_112 EIIFPHCACDSRRKG-HVITAISITHFKLHACTEEGQLENQVIAFEWDEMQRW-------
         430       440        450       460       470              

      330       340       350       360       370       380        
pF1KSD LPSGSTSSPGRGRGEVRLELAFEYLMSKDRLQWVTITSPQAIMMSICLQSMVDELMVKKS
           .:.  :       . . :::  .. . .:: : .:   .:  :.. .  ::  .: 
NP_112 ----DTDEEG-------MAFCFEYARGEKKPRWVKIFTPYFNYMHECFERVFCELKWRKE
           480              490       500       510       520      

      390       400       410       420       430       440        
pF1KSD GGSIRKMLRRRVGGTLRRSDSQQAVKSPPLLESPDATRESMVKLSSKLSAVSLRGIGSPS
                                                                   
NP_112 EY                                                          
                                                                   

>>NP_001317652 (OMIM: 611541) sorting nexin-27 isoform 1  (541 aa)
 initn: 269 init1: 174 opt: 406  Z-score: 455.8  bits: 93.9 E(85289): 1.2e-18
Smith-Waterman score: 438; 25.8% identity (57.9% similar) in 399 aa overlap (4-397:166-533)

                                          10        20        30   
pF1KSD                            MHFSIPETESRSGDSGGSAYVAYNIHVNGVLHC
                                     :.:.   .  ...:  .:.::... :   :
NP_001 PPHEADNLDPSDDSLGQSFYDYTEKQAVPISVPR--YKHVEQNGEKFVVYNVYMAGRQLC
         140       150       160         170       180       190   

            40        50        60        70        80        90   
pF1KSD RVRYSQLLGLHEQLRKEYGANVLPAFPPKKLFSLTPAEVEQRREQLEKYMQAVRQDPLLG
         :: ..  ::..:..:..  ..: .: :  :::.  ... ::. ::.:.. : .  ..:
NP_001 SKRYREFAILHQNLKREFANFTFPRLPGKWPFSLSEQQLDARRRGLEEYLEKVCSIRVIG
           200       210       220       230       240       250   

           100       110       120       130       140       150   
pF1KSD SSETFNSFLRRAQQETQQVPTEEVSLEVLLSNGQKVLVNVLTSDQTEDVLEAVAAKLDLP
        :. .. :: ..... . :   .: :.: : .:  : : :  .. :..: .:.:::. . 
NP_001 ESDIMQEFLSESDENYNGVS--DVELRVALPDGTTVTVRVKKNSTTDQVYQAIAAKVGMD
           260       270         280       290       300       310 

           160       170       180        190       200       210  
pF1KSD DDLIGYFSLFLVREKEDGAFSFVRKLQEFELPY-VSVTSLRSQEYKIVLRKSYWDSAYDD
       .  ..::.::     :  . ::::::   :.:. . . .  :      :    :  . ..
NP_001 STTVNYFALF-----EVISHSFVRKLAPNEFPHKLYIQNYTSAVPGTCLTIRKWLFTTEE
             320            330       340       350       360      

              220       230       240       250       260       270
pF1KSD DVM--ENRVGLNLLYAQTVSDIERGWILVTKEQHRQLKSLQEKVSKKEFLRLAQTLRHYG
       ...  .: .... .. :.:.:...:.: . .:.  ::..: :. .   .: . .: . :.
NP_001 EILLNDNDLAVTYFFHQAVDDVKKGYIKA-EEKSYQLQKLYEQRKMVMYLNMLRTCEGYN
        370       380       390        400       410       420     

              280       290       300       310         320        
pF1KSD YLRFDACVADFPEKDCPVVVSAGNSELSLQLRLPGQQLREG--SFRVTRMRCWRVTSSVP
        . :  :. :  .:   :... . ....:.      ::..   .:.  .:. :       
NP_001 EIIFPHCACDSRRKG-HVITAISITHFKLHACTEEGQLENQVIAFEWDEMQRW-------
         430       440        450       460       470              

      330       340       350       360       370       380        
pF1KSD LPSGSTSSPGRGRGEVRLELAFEYLMSKDRLQWVTITSPQAIMMSICLQSMVDELMVKKS
           .:.  :       . . :::  .. . .:: : .:   .:  :.. .  ::  .: 
NP_001 ----DTDEEG-------MAFCFEYARGEKKPRWVKIFTPYFNYMHECFERVFCELKWRKE
           480              490       500       510       520      

      390       400       410       420       430       440        
pF1KSD GGSIRKMLRRRVGGTLRRSDSQQAVKSPPLLESPDATRESMVKLSSKLSAVSLRGIGSPS
         .: .: :                                                   
NP_001 --NIFQMARSQQRDVAT                                           
          530       540                                            

>>XP_016857906 (OMIM: 611541) PREDICTED: sorting nexin-2  (407 aa)
 initn: 291 init1: 174 opt: 390  Z-score: 439.7  bits: 90.5 E(85289): 9.4e-18
Smith-Waterman score: 420; 25.8% identity (57.8% similar) in 384 aa overlap (9-387:48-404)

                                     10        20        30        
pF1KSD                       MHFSIPETESRSGDSGGSAYVAYNIHVNGVLHCRVRYS
                                     .:.:: . .    .::... :   :  :: 
XP_016 GGGGGGGGSGLHCAGNGGGGGGGPRVVRIVKSESGYGFNVRGQVYNVYMAGRQLCSKRYR
        20        30        40        50        60        70       

       40        50        60        70        80        90        
pF1KSD QLLGLHEQLRKEYGANVLPAFPPKKLFSLTPAEVEQRREQLEKYMQAVRQDPLLGSSETF
       ..  ::..:..:..  ..: .: :  :::.  ... ::. ::.:.. : .  ..: :. .
XP_016 EFAILHQNLKREFANFTFPRLPGKWPFSLSEQQLDARRRGLEEYLEKVCSIRVIGESDIM
        80        90       100       110       120       130       

      100       110       120       130       140       150        
pF1KSD NSFLRRAQQETQQVPTEEVSLEVLLSNGQKVLVNVLTSDQTEDVLEAVAAKLDLPDDLIG
       . :: ..... . :   .: :.: : .:  : : :  .. :..: .:.:::. . .  ..
XP_016 QEFLSESDENYNGVS--DVELRVALPDGTTVTVRVKKNSTTDQVYQAIAAKVGMDSTTVN
       140       150         160       170       180       190     

      160       170       180        190       200       210       
pF1KSD YFSLFLVREKEDGAFSFVRKLQEFELPY-VSVTSLRSQEYKIVLRKSYWDSAYDDDVM--
       ::.:: :      . ::::::   :.:. . . .  :      :    :  . .....  
XP_016 YFALFEVI-----SHSFVRKLAPNEFPHKLYIQNYTSAVPGTCLTIRKWLFTTEEEILLN
         200            210       220       230       240       250

         220       230       240       250       260       270     
pF1KSD ENRVGLNLLYAQTVSDIERGWILVTKEQHRQLKSLQEKVSKKEFLRLAQTLRHYGYLRFD
       .: .... .. :.:.:...:.: . .:.  ::..: :. .   .: . .: . :. . : 
XP_016 DNDLAVTYFFHQAVDDVKKGYIKA-EEKSYQLQKLYEQRKMVMYLNMLRTCEGYNEIIFP
              260       270        280       290       300         

         280       290       300       310         320       330   
pF1KSD ACVADFPEKDCPVVVSAGNSELSLQLRLPGQQLREG--SFRVTRMRCWRVTSSVPLPSGS
        :. :  .:   :... . ....:.      ::..   .:.  .:. :           .
XP_016 HCACDSRRKG-HVITAISITHFKLHACTEEGQLENQVIAFEWDEMQRW-----------D
     310        320       330       340       350                  

           340       350       360       370       380       390   
pF1KSD TSSPGRGRGEVRLELAFEYLMSKDRLQWVTITSPQAIMMSICLQSMVDELMVKKSGGSIR
       :.  :       . . :::  .. . .:: : .:   .:  :.. .  ::  .:      
XP_016 TDEEG-------MAFCFEYARGEKKPRWVKIFTPYFNYMHECFERVFCELKWRKEEY   
       360              370       380       390       400          

           400       410       420       430       440       450   
pF1KSD KMLRRRVGGTLRRSDSQQAVKSPPLLESPDATRESMVKLSSKLSAVSLRGIGSPSTDASA




470 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Wed Nov  2 23:42:14 2016 done: Wed Nov  2 23:42:15 2016
 Total Scan time:  7.580 Total Display time:  0.030

Function used was FASTA [36.3.4 Apr, 2011]
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