Result of FASTA (ccds) for pF1KB8019
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8019, 670 aa
  1>>>pF1KB8019 670 - 670 aa - 670 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 9.7071+/-0.00101; mu= 2.3715+/- 0.061
 mean_var=323.9418+/-66.157, 0's: 0 Z-trim(114.8): 17  B-trim: 165 in 1/54
 Lambda= 0.071259
 statistics sampled from 15303 (15316) to 15303 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.774), E-opt: 0.2 (0.47), width:  16
 Scan time:  4.120

The best scores are:                                      opt bits E(32554)
CCDS22.1 DVL1 gene_id:1855|Hs108|chr1              ( 670) 4518 478.4 1.4e-134
CCDS81252.1 DVL1 gene_id:1855|Hs108|chr1           ( 695) 2504 271.4   3e-72
CCDS3253.1 DVL3 gene_id:1857|Hs108|chr3            ( 716) 1868 206.0 1.5e-52
CCDS11091.1 DVL2 gene_id:1856|Hs108|chr17          ( 736) 1682 186.9 8.7e-47


>>CCDS22.1 DVL1 gene_id:1855|Hs108|chr1                   (670 aa)
 initn: 4518 init1: 4518 opt: 4518  Z-score: 2529.7  bits: 478.4 E(32554): 1.4e-134
Smith-Waterman score: 4518; 100.0% identity (100.0% similar) in 670 aa overlap (1-670:1-670)

               10        20        30        40        50        60
pF1KB8 MAETKIIYHMDEEETPYLVKLPVAPERVTLADFKNVLSNRPVHAYKFFFKSMDQDFGVVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS22 MAETKIIYHMDEEETPYLVKLPVAPERVTLADFKNVLSNRPVHAYKFFFKSMDQDFGVVK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 EEIFDDNAKLPCFNGRVVSWLVLAEGAHSDAGSQGTDSHTDLPPPLERTGGIGDSRPPSF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS22 EEIFDDNAKLPCFNGRVVSWLVLAEGAHSDAGSQGTDSHTDLPPPLERTGGIGDSRPPSF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 HPNVASSRDGMDNETGTESMVSHRRERARRRNREEAARTNGHPRGDRRRDVGLPPDSAST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS22 HPNVASSRDGMDNETGTESMVSHRRERARRRNREEAARTNGHPRGDRRRDVGLPPDSAST
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 ALSSELESSSFVDSDEDGSTSRLSSSTEQSTSSRLIRKHKRRRRKQRLRQADRASSFSSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS22 ALSSELESSSFVDSDEDGSTSRLSSSTEQSTSSRLIRKHKRRRRKQRLRQADRASSFSSI
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 TDSTMSLNIVTVTLNMERHHFLGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS22 TDSTMSLNIVTVTLNMERHHFLGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDM
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 LLQVNDVNFENMSNDDAVRVLREIVSQTGPISLTVAKCWDPTPRSYFTVPRADPVRPIDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS22 LLQVNDVNFENMSNDDAVRVLREIVSQTGPISLTVAKCWDPTPRSYFTVPRADPVRPIDP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB8 AAWLSHTAALTGALPRYELEEAPLTVKSDMSAVVRVMQLPDSGLEIRDRMWLKITIANAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS22 AAWLSHTAALTGALPRYELEEAPLTVKSDMSAVVRVMQLPDSGLEIRDRMWLKITIANAV
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB8 IGADVVDWLYTHVEGFKERREARKYASSLLKHGFLRHTVNKITFSEQCYYVFGDLCSNLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS22 IGADVVDWLYTHVEGFKERREARKYASSLLKHGFLRHTVNKITFSEQCYYVFGDLCSNLA
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB8 TLNLNSGSSGTSDQDTLAPLPHPAAPWPLGQGYPYQYPGPPPCFPPAYQDPGFSYGSGST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS22 TLNLNSGSSGTSDQDTLAPLPHPAAPWPLGQGYPYQYPGPPPCFPPAYQDPGFSYGSGST
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB8 GSQQSEGSKSSGSTRSSRRAPGREKERRAAGAGGSGSESDHTAPSGVGSSWRERPAGQLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS22 GSQQSEGSKSSGSTRSSRRAPGREKERRAAGAGGSGSESDHTAPSGVGSSWRERPAGQLS
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB8 RGSSPRSQASATAPGLPPPHPTTKAYTVVGGPPGGPPVRELAAVPPELTGSRQSFQKAMG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS22 RGSSPRSQASATAPGLPPPHPTTKAYTVVGGPPGGPPVRELAAVPPELTGSRQSFQKAMG
              610       620       630       640       650       660

              670
pF1KB8 NPCEFFVDIM
       ::::::::::
CCDS22 NPCEFFVDIM
              670

>>CCDS81252.1 DVL1 gene_id:1855|Hs108|chr1                (695 aa)
 initn: 4500 init1: 2500 opt: 2504  Z-score: 1410.5  bits: 271.4 E(32554): 3e-72
Smith-Waterman score: 4454; 96.3% identity (96.4% similar) in 695 aa overlap (1-670:1-695)

               10        20        30        40        50        60
pF1KB8 MAETKIIYHMDEEETPYLVKLPVAPERVTLADFKNVLSNRPVHAYKFFFKSMDQDFGVVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 MAETKIIYHMDEEETPYLVKLPVAPERVTLADFKNVLSNRPVHAYKFFFKSMDQDFGVVK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 EEIFDDNAKLPCFNGRVVSWLVLAEGAHSDAGSQGTDSHTDLPPPLERTGGIGDSRPPSF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 EEIFDDNAKLPCFNGRVVSWLVLAEGAHSDAGSQGTDSHTDLPPPLERTGGIGDSRPPSF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 HPNVASSRDGMDNETGTESMVSHRRERARRRNREEAARTNGHPRGDRRRDVGLPPDSAST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 HPNVASSRDGMDNETGTESMVSHRRERARRRNREEAARTNGHPRGDRRRDVGLPPDSAST
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 ALSSELESSSFVDSDEDGSTSRLSSSTEQSTSSRLIRKHKRRRRKQRLRQADRASSFSSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 ALSSELESSSFVDSDEDGSTSRLSSSTEQSTSSRLIRKHKRRRRKQRLRQADRASSFSSI
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 TDSTMSLNIVTVTLNMERHHFLGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 TDSTMSLNIVTVTLNMERHHFLGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDM
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 LLQVNDVNFENMSNDDAVRVLREIVSQTGPISLTVAKCWDPTPRSYFTVPRADPVRPIDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 LLQVNDVNFENMSNDDAVRVLREIVSQTGPISLTVAKCWDPTPRSYFTVPRADPVRPIDP
              310       320       330       340       350       360

              370                                380       390     
pF1KB8 AAWLSHTAALTGALPRY-------------------------ELEEAPLTVKSDMSAVVR
       :::::::::::::::::                         .:::::::::::::::::
CCDS81 AAWLSHTAALTGALPRYGTSPCSSAVTRTSSSSLTSSVPGAPQLEEAPLTVKSDMSAVVR
              370       380       390       400       410       420

         400       410       420       430       440       450     
pF1KB8 VMQLPDSGLEIRDRMWLKITIANAVIGADVVDWLYTHVEGFKERREARKYASSLLKHGFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 VMQLPDSGLEIRDRMWLKITIANAVIGADVVDWLYTHVEGFKERREARKYASSLLKHGFL
              430       440       450       460       470       480

         460       470       480       490       500       510     
pF1KB8 RHTVNKITFSEQCYYVFGDLCSNLATLNLNSGSSGTSDQDTLAPLPHPAAPWPLGQGYPY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 RHTVNKITFSEQCYYVFGDLCSNLATLNLNSGSSGTSDQDTLAPLPHPAAPWPLGQGYPY
              490       500       510       520       530       540

         520       530       540       550       560       570     
pF1KB8 QYPGPPPCFPPAYQDPGFSYGSGSTGSQQSEGSKSSGSTRSSRRAPGREKERRAAGAGGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 QYPGPPPCFPPAYQDPGFSYGSGSTGSQQSEGSKSSGSTRSSRRAPGREKERRAAGAGGS
              550       560       570       580       590       600

         580       590       600       610       620       630     
pF1KB8 GSESDHTAPSGVGSSWRERPAGQLSRGSSPRSQASATAPGLPPPHPTTKAYTVVGGPPGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 GSESDHTAPSGVGSSWRERPAGQLSRGSSPRSQASATAPGLPPPHPTTKAYTVVGGPPGG
              610       620       630       640       650       660

         640       650       660       670
pF1KB8 PPVRELAAVPPELTGSRQSFQKAMGNPCEFFVDIM
       :::::::::::::::::::::::::::::::::::
CCDS81 PPVRELAAVPPELTGSRQSFQKAMGNPCEFFVDIM
              670       680       690     

>>CCDS3253.1 DVL3 gene_id:1857|Hs108|chr3                 (716 aa)
 initn: 1993 init1: 1198 opt: 1868  Z-score: 1057.0  bits: 206.0 E(32554): 1.5e-52
Smith-Waterman score: 2822; 63.8% identity (81.4% similar) in 709 aa overlap (1-654:1-700)

               10        20        30        40        50        60
pF1KB8 MAETKIIYHMDEEETPYLVKLPVAPERVTLADFKNVLSNRPVHAYKFFFKSMDQDFGVVK
       :.:::::::.: .:::::::::.  :::::::::.::. ::  .:::::::::.::::::
CCDS32 MGETKIIYHLDGQETPYLVKLPLPAERVTLADFKGVLQ-RP--SYKFFFKSMDDDFGVVK
               10        20        30         40          50       

               70        80        90       100       110       120
pF1KB8 EEIFDDNAKLPCFNGRVVSWLVLAEGAHSDAGSQGTDSHTDLPPPLERTGGIGDSRPPSF
       ::: :::::::::::::::::: :::.: : .   .:. ..::::.::::::::::::::
CCDS32 EEISDDNAKLPCFNGRVVSWLVSAEGSHPDPAPFCADNPSELPPPMERTGGIGDSRPPSF
        60        70        80        90       100       110       

               130       140       150        160       170        
pF1KB8 HPNVAS-SRDGMDNETGTESMVSHRRERARRRNR-EEAARTNGHPRGDRRRDVGLPPDSA
       ::.... :....::.: :.:.:: .::: :::.  :.:.: ::  .:.:::. :   ::.
CCDS32 HPHAGGGSQENLDNDTETDSLVSAQRERPRRRDGPEHATRLNGTAKGERRREPG-GYDSS
       120       130       140       150       160       170       

      180       190       200       210       220       230        
pF1KB8 STALSSELESSSFVDSDEDGSTSRLSSSTEQSTSSRLIRKHKRRRRKQRLRQADRASSFS
       :: .:::::..:: ::::: ::::.:::::::..:::.:.::::::::.. . .:.::::
CCDS32 STLMSSELETTSFFDSDEDDSTSRFSSSTEQSSASRLMRRHKRRRRKQKVSRIERSSSFS
        180       190       200       210       220       230      

      240       250       260       270       280       290        
pF1KB8 SITDSTMSLNIVTVTLNMERHHFLGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPG
       :::::::::::.:::::::...:::::::::::.::::::::::::::::::::::::::
CCDS32 SITDSTMSLNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPG
        240       250       260       270       280       290      

      300       310       320       330       340       350        
pF1KB8 DMLLQVNDVNFENMSNDDAVRVLREIVSQTGPISLTVAKCWDPTPRSYFTVPRADPVRPI
       :::::::..:::::::::::::::::: . :::.:::::::::.::. ::.::..:.:::
CCDS32 DMLLQVNEINFENMSNDDAVRVLREIVHKPGPITLTVAKCWDPSPRGCFTLPRSEPIRPI
        300       310       320       330       340       350      

      360       370                               380       390    
pF1KB8 DPAAWLSHTAALTGALPRY------------------------ELEEAPLTVKSDMSAVV
       :::::.:::::.::..: :                        .:..  :...:::.:.:
CCDS32 DPAAWVSHTAAMTGTFPAYGMSPSLSTITSTSSSITSSIPDTERLDDFHLSIHSDMAAIV
        360       370       380       390       400       410      

          400       410       420       430       440       450    
pF1KB8 RVMQLPDSGLEIRDRMWLKITIANAVIGADVVDWLYTHVEGFKERREARKYASSLLKHGF
       ..:  :.::::.:::::::::: :: ::.::::::: .:::: .:::::::::.::: ::
CCDS32 KAMASPESGLEVRDRMWLKITIPNAFIGSDVVDWLYHNVEGFTDRREARKYASNLLKAGF
        420       430       440       450       460       470      

          460       470       480         490       500        510 
pF1KB8 LRHTVNKITFSEQCYYVFGDLCSNLATLNLNS--GSSGTSDQDTLAPLPHP-AAPWPLGQ
       .:::::::::::::::.:::::.:.:.:.:..  ::::.:::::::::::: :::::.. 
CCDS32 IRHTVNKITFSEQCYYIFGDLCGNMANLSLHDHDGSSGASDQDTLAPLPHPGAAPWPMA-
        480       490       500       510       520       530      

             520         530       540       550         560       
pF1KB8 GYPYQYPGPP-PCFP-PAYQDPGFSYGSGSTGSQQSEGSKSSGSTRSS--RRAPGREKER
        .::::: :: :  : :.. . :.:::.::..::.::::.::::.::.  ::   .::. 
CCDS32 -FPYQYPPPPHPYNPHPGFPELGYSYGGGSASSQHSEGSRSSGSNRSGSDRR---KEKDP
          540       550       560       570       580          590 

       570         580             590              600            
pF1KB8 RAAGA--GGSGSESDHTAPSGV------GSSWRERPAG-------QLSRGSSPRSQ---A
       .:. .  ::::::::::. :..      . : :  ::.       . : .:: ::.    
CCDS32 KAGDSKSGGSGSESDHTTRSSLRGPRERAPSERSGPAASEHSHRSHHSLASSLRSHHTHP
             600       610       620       630       640       650 

     610           620       630       640       650       660     
pF1KB8 SATAPGLPP----PHPTTKAYTVVGGPPGGPPVRELAAVPPELTGSRQSFQKAMGNPCEF
       :   ::.::    :        .. ::::.:: :.::.::::::.::::           
CCDS32 SYGPPGVPPLYGPPMLMMPPPPAAMGPPGAPPGRDLASVPPELTASRQSFRMAMGNPSEF
             660       670       680       690       700       710 

         670
pF1KB8 FVDIM
            
CCDS32 FVDVM
            

>>CCDS11091.1 DVL2 gene_id:1856|Hs108|chr17               (736 aa)
 initn: 1782 init1: 1135 opt: 1682  Z-score: 953.5  bits: 186.9 E(32554): 8.7e-47
Smith-Waterman score: 2543; 59.3% identity (77.5% similar) in 717 aa overlap (1-652:11-718)

                         10        20        30        40        50
pF1KB8           MAETKIIYHMDEEETPYLVKLPVAPERVTLADFKNVLSNRPVHAYKFFFK
                 ..:::.:::.::::::::::.::  ::.::.:::.::. ::. : :.:::
CCDS11 MAGSSTGGGGVGETKVIYHLDEEETPYLVKIPVPAERITLGDFKSVLQ-RPAGA-KYFFK
               10        20        30        40         50         

               60        70        80        90       100          
pF1KB8 SMDQDFGVVKEEIFDDNAKLPCFNGRVVSWLVLAEGAHSDAGSQGTDSHTDLPPPL----
       ::::::::::::: ::::.::::::::::::: ... . . .    . ...: ::     
CCDS11 SMDQDFGVVKEEISDDNARLPCFNGRVVSWLVSSDNPQPEMAPPVHEPRAELAPPAPPLP
       60        70        80        90       100       110        

            110       120       130       140       150            
pF1KB8 ----ERTGGIGDSRPPSFHPNVASSRDGMDNETGTESMVSHRRERARRRNREE---AART
           :::.::::::::::::::.::..... :: :::.:: :::: :::.  :   ... 
CCDS11 PLPPERTSGIGDSRPPSFHPNVSSSHENLEPETETESVVSLRRERPRRRDSSEHGAGGHR
      120       130       140       150       160       170        

     160       170       180       190       200       210         
pF1KB8 NGHPRGDRRRDVGLPPDSASTALSSELESSSFVDSDEDGSTSRLSSSTEQSTSSRLIRKH
       .: :   .:. .:   .:.:: ..:::::.:. ::::. . ::.:::::::..:::...:
CCDS11 TGGPSRLERHLAGY--ESSSTLMTSELESTSLGDSDEEDTMSRFSSSTEQSSASRLLKRH
      180       190         200       210       220       230      

     220       230       240       250       260       270         
pF1KB8 KRRRRKQRLRQADRASSFSSITDSTMSLNIVTVTLNMERHHFLGISIVGQSNDRGDGGIY
        :::::::  . .:.:::::.:::::::::.:::::::...:::::::::::.:::::::
CCDS11 -RRRRKQRPPRLERTSSFSSVTDSTMSLNIITVTLNMEKYNFLGISIVGQSNERGDGGIY
         240       250       260       270       280       290     

     280       290       300       310       320       330         
pF1KB8 IGSIMKGGAVAADGRIEPGDMLLQVNDVNFENMSNDDAVRVLREIVSQTGPISLTVAKCW
       :::::::::::::::::::::::::::.:::::::::::::::.:: . ::: :::::::
CCDS11 IGSIMKGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAVRVLRDIVHKPGPIVLTVAKCW
         300       310       320       330       340       350     

     340       350       360       370                        380  
pF1KB8 DPTPRSYFTVPRADPVRPIDPAAWLSHTAALTGALPRYE-----------------LEEA
       ::.:..:::.:: .:..:::::::.::.:::::..: :                   :  
CCDS11 DPSPQAYFTLPRNEPIQPIDPAAWVSHSAALTGTFPAYPGSSSMSTITSGSSLPDGCEGR
         360       370       380       390       400       410     

            390       400       410       420       430       440  
pF1KB8 PLTVKSDMSAVVRVMQLPDSGLEIRDRMWLKITIANAVIGADVVDWLYTHVEGFKERREA
        :.:..::..:...:  :.::::.:::::::::: :: .:.::::::: ::::: :::::
CCDS11 GLSVHTDMASVTKAMAAPESGLEVRDRMWLKITIPNAFLGSDVVDWLYHHVEGFPERREA
         420       430       440       450       460       470     

            450       460       470           480         490      
pF1KB8 RKYASSLLKHGFLRHTVNKITFSEQCYYVFGDL---C-SNLATLNLNS--GSSGTSDQDT
       :::::.::: :..::::::::::::::::::::   : : :..:.::.  ::::.:::::
CCDS11 RKYASGLLKAGLIRHTVNKITFSEQCYYVFGDLSGGCESYLVNLSLNDNDGSSGASDQDT
         480       490       500       510       520       530     

        500       510       520         530        540       550   
pF1KB8 LAPLPHPAAPWPLGQGYPYQYPGPPPCFP--PAYQD-PGFSYGSGSTGSQQSEGSKSSGS
       :::::  :.::::   . ::::.: :  :  : :..  ...::.::..::.::::.::::
CCDS11 LAPLPG-ATPWPLLPTFSYQYPAPHPYSPQPPPYHELSSYTYGGGSASSQHSEGSRSSGS
         540        550       560       570       580       590    

           560         570       580       590        600       610
pF1KB8 TRSSRRA--PGREKERRAAGAGGSGSESDHTAPSGVGSSWRER-PAGQLSRGSSPRSQAS
       :::.  :   :: .::   . .::::::.   ::. :.: :.   :.  : :. : :..:
CCDS11 TRSDGGAGRTGRPEERAPESKSGSGSESE---PSSRGGSLRRGGEASGTSDGGPPPSRGS
          600       610       620          630       640       650 

                         620          630                  640     
pF1KB8 ATA-------PGL----PPPH---PTTKAYTVVGGPP-----------GGPPVRELAAVP
       . .       :::    :::    : .  ..:.  ::           :.::::.:..::
CCDS11 TGGAPNLRAHPGLHPYGPPPGMALPYNPMMVVMMPPPPPPVPPAVQPPGAPPVRDLGSVP
             660       670       680       690       700       710 

         650       660       670
pF1KB8 PELTGSRQSFQKAMGNPCEFFVDIM
       ::::.::                  
CCDS11 PELTASRQSFHMAMGNPSEFFVDVM
             720       730      




670 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Wed Nov  2 23:16:05 2016 done: Wed Nov  2 23:16:05 2016
 Total Scan time:  4.120 Total Display time:  0.040

Function used was FASTA [36.3.4 Apr, 2011]
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