Result of FASTA (omim) for
pF1KB3954
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3954, 1466 aa
1>>>pF1KB3954 1466 - 1466 aa - 1466 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 16.2922+/-0.000618; mu= -23.4943+/- 0.039
mean_var=952.4231+/-195.832, 0's: 0 Z-trim(122.6): 734 B-trim: 0 in 0/60
Lambda= 0.041558
statistics sampled from 40216 (41002) to 40216 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.707), E-opt: 0.2 (0.481), width: 16
Scan time: 20.730
The best scores are: opt bits E(85289)
NP_000081 (OMIM: 120180,130020,130050) collagen al (1466) 11027 678.3 1.1e-193
NP_000079 (OMIM: 114000,120150,130000,130060,16620 (1464) 6618 414.0 4.3e-114
NP_149162 (OMIM: 108300,120140,132450,150600,15121 (1418) 6387 400.1 6.2e-110
XP_016874319 (OMIM: 108300,120140,132450,150600,15 (1465) 6387 400.2 6.4e-110
NP_001835 (OMIM: 108300,120140,132450,150600,15121 (1487) 6371 399.2 1.3e-109
XP_016874318 (OMIM: 108300,120140,132450,150600,15 (1534) 6371 399.2 1.3e-109
XP_016874317 (OMIM: 108300,120140,132450,150600,15 (1535) 6370 399.2 1.3e-109
XP_016874320 (OMIM: 108300,120140,132450,150600,15 (1305) 6151 385.9 1.1e-105
XP_011522643 (OMIM: 114000,120150,130000,130060,16 (1398) 5691 358.4 2.3e-97
XP_011508875 (OMIM: 120190,130000) PREDICTED: coll (1453) 5609 353.5 7e-96
NP_000384 (OMIM: 120190,130000) collagen alpha-2(V (1499) 5609 353.5 7.1e-96
XP_005257115 (OMIM: 114000,120150,130000,130060,16 (1374) 4651 296.0 1.3e-78
XP_005257116 (OMIM: 114000,120150,130000,130060,16 (1158) 4483 285.9 1.3e-75
NP_000080 (OMIM: 120160,130060,166210,166220,16671 (1366) 4355 278.3 2.9e-73
NP_001265003 (OMIM: 120215,130000) collagen alpha- (1838) 4186 268.3 4e-70
NP_000084 (OMIM: 120215,130000) collagen alpha-1(V (1838) 4184 268.2 4.3e-70
NP_542197 (OMIM: 120280,154780,228520,603932,60484 (1690) 4110 263.7 8.8e-69
NP_001177638 (OMIM: 120280,154780,228520,603932,60 (1767) 4110 263.7 9.1e-69
NP_001845 (OMIM: 120280,154780,228520,603932,60484 (1806) 4110 263.7 9.2e-69
NP_542196 (OMIM: 120280,154780,228520,603932,60484 (1818) 4110 263.7 9.2e-69
XP_016855824 (OMIM: 120280,154780,228520,603932,60 (1855) 4110 263.7 9.4e-69
XP_016855823 (OMIM: 120280,154780,228520,603932,60 (1857) 4110 263.7 9.4e-69
XP_016855826 (OMIM: 120280,154780,228520,603932,60 (1323) 3940 253.4 8.7e-66
XP_016869755 (OMIM: 120215,130000) PREDICTED: coll (1715) 3855 248.4 3.6e-64
XP_016865740 (OMIM: 120290,184840,215150,277610,60 (1342) 3828 246.7 9.2e-64
XP_011512604 (OMIM: 120290,184840,215150,277610,60 (1365) 3828 246.7 9.3e-64
XP_011512602 (OMIM: 120290,184840,215150,277610,60 (1438) 3828 246.7 9.7e-64
XP_011512601 (OMIM: 120290,184840,215150,277610,60 (1498) 3828 246.7 1e-63
NP_542410 (OMIM: 120290,184840,215150,277610,60186 (1629) 3828 246.8 1.1e-63
NP_542412 (OMIM: 120290,184840,215150,277610,60186 (1650) 3828 246.8 1.1e-63
XP_016865739 (OMIM: 120290,184840,215150,277610,60 (1736) 3828 246.8 1.1e-63
NP_542411 (OMIM: 120290,184840,215150,277610,60186 (1736) 3828 246.8 1.1e-63
XP_011526344 (OMIM: 120216) PREDICTED: collagen al (1744) 3492 226.7 1.3e-57
NP_056534 (OMIM: 120216) collagen alpha-3(V) chain (1745) 3492 226.7 1.3e-57
XP_011508872 (OMIM: 120131,203780) PREDICTED: coll (1414) 3283 214.0 6.6e-54
XP_016858789 (OMIM: 120131,203780) PREDICTED: coll (1414) 3283 214.0 6.6e-54
XP_011508871 (OMIM: 120131,203780) PREDICTED: coll (1414) 3283 214.0 6.6e-54
XP_011508870 (OMIM: 120131,203780) PREDICTED: coll (1419) 3283 214.0 6.6e-54
XP_016858788 (OMIM: 120131,203780) PREDICTED: coll (1518) 3284 214.1 6.6e-54
XP_016858787 (OMIM: 120131,203780) PREDICTED: coll (1608) 3284 214.2 6.9e-54
XP_011508863 (OMIM: 120131,203780) PREDICTED: coll (1608) 3284 214.2 6.9e-54
XP_011508864 (OMIM: 120131,203780) PREDICTED: coll (1608) 3284 214.2 6.9e-54
XP_011508861 (OMIM: 120131,203780) PREDICTED: coll (1612) 3284 214.2 6.9e-54
XP_011508862 (OMIM: 120131,203780) PREDICTED: coll (1612) 3284 214.2 6.9e-54
XP_006712309 (OMIM: 120131,203780) PREDICTED: coll (1627) 3284 214.2 6.9e-54
XP_016858785 (OMIM: 120131,203780) PREDICTED: coll (1659) 3284 214.2 7e-54
XP_005246338 (OMIM: 120131,203780) PREDICTED: coll (1690) 3284 214.2 7.1e-54
NP_000083 (OMIM: 120131,203780) collagen alpha-4(I (1690) 3284 214.2 7.1e-54
XP_011508867 (OMIM: 120131,203780) PREDICTED: coll (1424) 3281 213.9 7.2e-54
XP_011508869 (OMIM: 120131,203780) PREDICTED: coll (1420) 3280 213.9 7.5e-54
>>NP_000081 (OMIM: 120180,130020,130050) collagen alpha- (1466 aa)
initn: 11027 init1: 11027 opt: 11027 Z-score: 3597.9 bits: 678.3 E(85289): 1.1e-193
Smith-Waterman score: 11027; 100.0% identity (100.0% similar) in 1466 aa overlap (1-1466:1-1466)
10 20 30 40 50 60
pF1KB3 MMSFVQKGSWLLLALLHPTIILAQQEAVEGGCSHLGQSYADRDVWKPEPCQICVCDSGSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MMSFVQKGSWLLLALLHPTIILAQQEAVEGGCSHLGQSYADRDVWKPEPCQICVCDSGSV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 LCDDIICDDQELDCPNPEIPFGECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LCDDIICDDQELDCPNPEIPFGECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 GDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 PPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 ERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 PRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 SNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 ANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 AAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 SPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 GPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 PKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 TPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKG
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 EGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPG
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB3 VAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPG
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB3 KDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAG
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB3 PPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDG
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB3 LPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAG
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB3 SRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRG
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB3 PVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPCCGGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPCCGGV
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB3 GAAAIAGIGGEKAGGFAPYYGDEPMDFKINTDEIMTSLKSVNGQIESLISPDGSRKNPAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GAAAIAGIGGEKAGGFAPYYGDEPMDFKINTDEIMTSLKSVNGQIESLISPDGSRKNPAR
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KB3 NCRDLKFCHPELKSGEYWVDPNQGCKLDAIKVFCNMETGETCISANPLNVPRKHWWTDSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 NCRDLKFCHPELKSGEYWVDPNQGCKLDAIKVFCNMETGETCISANPLNVPRKHWWTDSS
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KB3 AEKKHVWFGESMDGGFQFSYGNPELPEDVLDVQLAFLRLLSSRASQNITYHCKNSIAYMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AEKKHVWFGESMDGGFQFSYGNPELPEDVLDVQLAFLRLLSSRASQNITYHCKNSIAYMD
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KB3 QASGNVKKALKLMGSNEGEFKAEGNSKFTYTVLEDGCTKHTGEWSKTVFEYRTRKAVRLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QASGNVKKALKLMGSNEGEFKAEGNSKFTYTVLEDGCTKHTGEWSKTVFEYRTRKAVRLP
1390 1400 1410 1420 1430 1440
1450 1460
pF1KB3 IVDIAPYDIGGPDQEFGVDVGPVCFL
::::::::::::::::::::::::::
NP_000 IVDIAPYDIGGPDQEFGVDVGPVCFL
1450 1460
>>NP_000079 (OMIM: 114000,120150,130000,130060,166200,16 (1464 aa)
initn: 8206 init1: 4979 opt: 6618 Z-score: 2169.3 bits: 414.0 E(85289): 4.3e-114
Smith-Waterman score: 6622; 61.9% identity (74.1% similar) in 1487 aa overlap (1-1466:1-1464)
10 20 30 40
pF1KB3 MMSFVQKGSWLLLALLHPTIILA--QQEA-VEGG--------CSHLGQSYADRDVWKPEP
:.::: . :: :: : .:. :.:. ::: : . : : :::::::::
NP_000 MFSFV---DLRLLLLLAATALLTHGQEEGQVEGQDEDIPPITCVQNGLRYHDRDVWKPEP
10 20 30 40 50
50 60 70 80 90 100
pF1KB3 CQICVCDSGSVLCDDIICDDQELDCPNPEIPFGECCAVCPQPPTAPT-RPPNG-QGPQG-
:.:::::.:.:::::.:::. . .::. :.: :::: :::. .:: . .: .::.:
NP_000 CRICVCDNGKVLCDDVICDETK-NCPGAEVPEGECCPVCPDGSESPTDQETTGVEGPKGD
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB3 --PKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTG-PQNYSPQYD-SYDVKS
:.: :: : :::.: :: :: :: :: ::::: : : :..:: . .:: ::
NP_000 TGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPG-----PPGLGGNFAPQLSYGYDEKS
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB3 GVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIG
.::.. ::: :: :: : :: ::.:: :.::::::::. : ::: :: : :
NP_000 ---TGGIS-VPGPMGPSGPRGLPGP---PGAPGPQGFQGPPGEPGEPGASGPMGPRGPPG
180 190 200 210 220
230 240 250 260 270 280
pF1KB3 PSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPG
: : : :::.:.:::::::: ::: : .: : :.:::::::::.: .: ::..: :
NP_000 PPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAG
230 240 250 260 270 280
290 300 310 320 330 340
pF1KB3 LKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAG
::: : :::::::: ::::: :::::::: :: ::::::::: :. : ::: :: : :
NP_000 PKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPG
290 300 310 320 330 340
350 360 370 380 390 400
pF1KB3 FPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAG
:::. :::::.:: : ::.: : :::::: : ::: :: : :: .:.::.:: : :
NP_000 FPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPG
350 360 370 380 390 400
410 420 430 440 450 460
pF1KB3 IPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKG
: ::::. ::::: :: : .: :: .:..:::: :.::. : .:: : .:. : :: :
NP_000 IAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAG
410 420 430 440 450 460
470 480 490 500 510 520
pF1KB3 EDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAG
:.:: :. :::: .:::: ::::.:: :: : .:. : ::::::::.::::::.:. :
NP_000 EEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPG
470 480 490 500 510 520
530 540 550 560 570 580
pF1KB3 EPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPG
: :: : : :: .:. ::::.:: ::: :::: :..:::::::: : ::: :::::::
NP_000 EAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPG
530 540 550 560 570 580
590 600 610 620 630 640
pF1KB3 PKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQG
::: : ::: :::: :: :: :: ::.::.: ::::::.::.:..:. :: : :.::
NP_000 PKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQG
590 600 610 620 630 640
650 660 670 680 690 700
pF1KB3 LPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPG
::: .::::: ::::: : :: :::: :..:. : ::::: : : : ::. : ::
NP_000 LPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPG
650 660 670 680 690 700
710 720 730 740 750 760
pF1KB3 PEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRG
.:.:: :: :: ::. :.:::::::::::. : ::::::.:. : :::: ::::: ::
NP_000 NDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRG
710 720 730 740 750 760
770 780 790 800 810 820
pF1KB3 PTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPG
::::::::::: ::::::.: : : .: ::.::.::: :::::::: : :: .:.::
NP_000 LTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPG
770 780 790 800 810 820
830 840 850 860 870 880
pF1KB3 GKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPG
.::: : : ::..:::: ::: : :: : : :.:: ::: : :::.::::: : :
NP_000 AKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVG
830 840 850 860 870 880
890 900 910 920 930 940
pF1KB3 PPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPG
::: .:: ::::: : ::.: :: :.:: : :: :: : : ::::::::.:: :
NP_000 PPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAG
890 900 910 920 930 940
950 960 970 980 990 1000
pF1KB3 APGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPG
::: : ::.: ::..: ::. : :: :: : .:: :: : .: :::::::::.: ::
NP_000 APGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPG
950 960 970 980 990 1000
1010 1020 1030 1040 1050 1060
pF1KB3 LAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSG
::: :: ::.: ::..: ::::::::.::::::.: : ::::: :: :::::::::::
NP_000 LAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSG
1010 1020 1030 1040 1050 1060
1070 1080 1090 1100 1110 1120
pF1KB3 DRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPG
::::.::::::: ::.:.:: ::::::::::::::.: :::::::: : : :: ::
NP_000 DRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPG
1070 1080 1090 1100 1110 1120
1130 1140 1150 1160 1170 1180
pF1KB3 PAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPG
:.:: :. :::::::: : .: ::::: .: ::::::::::: :. : : :: ::
NP_000 SPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPG
1130 1140 1150 1160 1170 1180
1190 1200 1210 1220 1230 1240
pF1KB3 QPGPPGPPGAPGPCCGGVGAAAIAGIGGEKAGGFAPYYGDEPMDFKINTD-EIMTSLKSV
:::::::.: : . . ::: . :: . . . : :. :.:::.
NP_000 PPGPPGPPSA------GFDFSFLPQPPQEKAHDGGRYYRADDANVVRDRDLEVDTTLKSL
1190 1200 1210 1220 1230
1250 1260 1270 1280 1290 1300
pF1KB3 NGQIESLISPDGSRKNPARNCRDLKFCHPELKSGEYWVDPNQGCKLDAIKVFCNMETGET
. :::.. ::.::::::::.:::::.:: . ::::::.::::::.:::::::::::::::
NP_000 SQQIENIRSPEGSRKNPARTCRDLKMCHSDWKSGEYWIDPNQGCNLDAIKVFCNMETGET
1240 1250 1260 1270 1280 1290
1310 1320 1330 1340 1350
pF1KB3 CISANPLNVPRKHWW-TDSSAEKKHVWFGESMDGGFQFSYGNP-ELPEDVLDVQLAFLRL
:. . .: .:.:. . . .:.:::::::: :::: ::. : :: .::.::::
NP_000 CVYPTQPSVAQKNWYISKNPKDKRHVWFGESMTDGFQFEYGGQGSDPADVA-IQLTFLRL
1300 1310 1320 1330 1340 1350
1360 1370 1380 1390 1400 1410
pF1KB3 LSSRASQNITYHCKNSIAYMDQASGNVKKALKLMGSNEGEFKAEGNSKFTYTVLEDGCTK
.:..::::::::::::.::::: .::.:::: :.:::: :..:::::.:::.: ::::.
NP_000 MSTEASQNITYHCKNSVAYMDQQTGNLKKALLLQGSNEIEIRAEGNSRFTYSVTVDGCTS
1360 1370 1380 1390 1400 1410
1420 1430 1440 1450 1460
pF1KB3 HTGEWSKTVFEYRTRKAVRLPIVDIAPYDIGGPDQEFGVDVGPVCFL
::: :.:::.::.: :. ::::.:.:: :.:.:::::: ::::::::
NP_000 HTGAWGKTVIEYKTTKTSRLPIIDVAPLDVGAPDQEFGFDVGPVCFL
1420 1430 1440 1450 1460
>>NP_149162 (OMIM: 108300,120140,132450,150600,151210,15 (1418 aa)
initn: 4885 init1: 4885 opt: 6387 Z-score: 2094.6 bits: 400.1 E(85289): 6.2e-110
Smith-Waterman score: 6387; 61.8% identity (75.6% similar) in 1412 aa overlap (67-1466:23-1418)
40 50 60 70 80 90
pF1KB3 QSYADRDVWKPEPCQICVCDSGSVLCDDIICDDQELDCPNPEIPFGECC----AVCPQPP
:. :.. :.:. :: : :. :
NP_149 MIRLGAPQTLVLLTLLVAAVLRCQGQDVRQPGPKGQKGEPGDIKDIVGPKGP
10 20 30 40 50
100 110 120 130 140
pF1KB3 TAPTRPPNGQGPQGPKGDPGPPGIPG---RNGDPGIPGQPGSPGSPGPPGICESCPTG-P
.: : . :::.: .:: : : :: :.:.:: ::.:: :: ::::: : :
NP_149 PGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPG-----PPGLG
60 70 80 90 100
150 160 170 180 190 200
pF1KB3 QNYSPQY-DSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPG
:.. :. ..: :.: : :. . :: :: :: :::: . :.:: :.:: :::::
NP_149 GNFAAQMAGGFDEKAGGAQLGV--MQGPMGPMGPRGPPGPA---GAPGPQGFQGNPGEPG
110 120 130 140 150 160
210 220 230 240 250 260
pF1KB3 QAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRG
. : ::: :: : :: : : :::.:.::. :::: ::: : .: : ::.::.:::::
NP_149 EPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRG
170 180 190 200 210 220
270 280 290 300 310 320
pF1KB3 FDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARG
. : .: :::.::::.:::.: :::::.:::::::: :::::: : :::::::::: :
NP_149 YPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPG
230 240 250 260 270 280
330 340 350 360 370 380
pF1KB3 SDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPG
: ::: :: : ::::.::::::.::.:. : .:: : ::::: : : : : ::
NP_149 PAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPG
290 300 310 320 330 340
390 400 410 420 430 440
pF1KB3 INGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRG
.: ::.:: : :: ::::. : :::::: ::.: : .: .:::: : ::: ::.:
NP_149 TDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKG
350 360 370 380 390 400
450 460 470 480 490 500
pF1KB3 ERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAG
: : :: :.:: ::.:: :. ::::. : : ::::::: :: : .:. : :: :
NP_149 EPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPG
410 420 430 440 450 460
510 520 530 540 550 560
pF1KB3 ERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPG
::: : :::.:: :.::: : :: :: ::. : :: : .:: :: :. ::.:::::::
NP_149 ERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPG
470 480 490 500 510 520
570 580 590 600 610 620
pF1KB3 PSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGG
:.: :::::::::::::: .: ::: ::.: ::.:: .: :::.:::: :::::.::.:
NP_149 PQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAG
530 540 550 560 570 580
630 640 650 660 670 680
pF1KB3 DKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPG
..:. : :::.:.::::: :::::.::::. : :.::::: : .:. : ::::: ::
NP_149 ERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPG
590 600 610 620 630 640
690 700 710 720 730 740
pF1KB3 LAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPG
: : :: : :: .: :::.:: ::::: : :::::::::::. : :::::.:. :
NP_149 AQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVG
650 660 670 680 690 700
750 760 770 780 790 800
pF1KB3 GPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPG
: .:.::::: :: ::::::::::: :.::: : :: : :: ::.:::::::::::
NP_149 EKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPG
710 720 730 740 750 760
810 820 830 840 850 860
pF1KB3 PAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPG
:::: : :: .:.::.:::.: :.::..: :: :: :. :: :: : : :: ::. :
NP_149 PAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQG
770 780 790 800 810 820
870 880 890 900 910 920
pF1KB3 GPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAG
:::.::::: : :::::::::::::: : ::::: : :..: :: : : .: ::
NP_149 PPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAG
830 840 850 860 870 880
930 940 950 960 970 980
pF1KB3 QPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANG
::::: :: .:: :: :: : :..: ::..: ::. : :: :: : .:: :: :: :
NP_149 PPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPG
890 900 910 920 930 940
990 1000 1010 1020 1030 1040
pF1KB3 LSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPG
::.:::::: : :::.: ::::::.:.::.:: :::::. : ::::::.:. :::::::
NP_149 ASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPG
950 960 970 980 990 1000
1050 1060 1070 1080 1090 1100
pF1KB3 HPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKG
:: :::.::.::.:::::.: :: : ::::.:: :::::::::::.:: : :.::
NP_149 PPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKG
1010 1020 1030 1040 1050 1060
1110 1120 1130 1140 1150 1160
pF1KB3 HRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRG
:::: : : :: :::.:.::: : ::.::::: :: :: ::::..: :::::::::::
NP_149 HRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRG
1070 1080 1090 1100 1110 1120
1170 1180 1190 1200 1210 1220
pF1KB3 NRGERGSEGSPGHPGQPGPPGPPGAPGPCCGGVGAAAIAGIGGEKAGGFAPYY--GDEPM
:: : : ::.:: :::::: ::: :. .:.::.: .. : : .:.
NP_149 RSGETGPAGPPGNPG---PPGPPGPPGP---GIDMSAFAGLGPREKGPDPLQYMRADQAA
1130 1140 1150 1160 1170
1230 1240 1250 1260 1270 1280
pF1KB3 D-FKINTDEIMTSLKSVNGQIESLISPDGSRKNPARNCRDLKFCHPELKSGEYWVDPNQG
.. . :. ..:::.:.::::. ::.::::::::.:::::.:::: :::.::.:::::
NP_149 GGLRQHDAEVDATLKSLNNQIESIRSPEGSRKNPARTCRDLKLCHPEWKSGDYWIDPNQG
1180 1190 1200 1210 1220 1230
1290 1300 1310 1320 1330 1340
pF1KB3 CKLDAIKVFCNMETGETCISANPLNVPRKHWWTDSSAEKKHVWFGESMDGGFQFSYGNPE
: :::.::::::::::::. :: :::.:.::...: ::::.::::...:::.::::. .
NP_149 CTLDAMKVFCNMETGETCVYPNPANVPKKNWWSSKSKEKKHIWFGETINGGFHFSYGDDN
1240 1250 1260 1270 1280 1290
1350 1360 1370 1380 1390 1400
pF1KB3 LPEDVLDVQLAFLRLLSSRASQNITYHCKNSIAYMDQASGNVKKALKLMGSNEGEFKAEG
: .. .::..::::::...::::::::::::::.:.:.::.:::: ..:::. :..:::
NP_149 LAPNTANVQMTFLRLLSTEGSQNITYHCKNSIAYLDEAAGNLKKALLIQGSNDVEIRAEG
1300 1310 1320 1330 1340 1350
1410 1420 1430 1440 1450 1460
pF1KB3 NSKFTYTVLEDGCTKHTGEWSKTVFEYRTRKAVRLPIVDIAPYDIGGPDQEFGVDVGPVC
::.::::.:.::::::::.:.:::.:::..:. ::::.::::.:::::.::::::.::::
NP_149 NSRFTYTALKDGCTKHTGKWGKTVIEYRSQKTSRLPIIDIAPMDIGGPEQEFGVDIGPVC
1360 1370 1380 1390 1400 1410
pF1KB3 FL
::
NP_149 FL
>>XP_016874319 (OMIM: 108300,120140,132450,150600,151210 (1465 aa)
initn: 4885 init1: 4885 opt: 6387 Z-score: 2094.4 bits: 400.2 E(85289): 6.4e-110
Smith-Waterman score: 6387; 61.8% identity (75.6% similar) in 1412 aa overlap (67-1466:70-1465)
40 50 60 70 80 90
pF1KB3 QSYADRDVWKPEPCQICVCDSGSVLCDDIICDDQELDCPNPEIPFGECC----AVCPQPP
:. :.. :.:. :: : :. :
XP_016 QEKRPAKPWEEGSLAKTLVLLTLLVAAVLRCQGQDVRQPGPKGQKGEPGDIKDIVGPKGP
40 50 60 70 80 90
100 110 120 130 140
pF1KB3 TAPTRPPNGQGPQGPKGDPGPPGIPG---RNGDPGIPGQPGSPGSPGPPGICESCPTG-P
.: : . :::.: .:: : : :: :.:.:: ::.:: :: ::::: : :
XP_016 PGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPG-----PPGLG
100 110 120 130 140 150
150 160 170 180 190 200
pF1KB3 QNYSPQY-DSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPG
:.. :. ..: :.: : :. . :: :: :: :::: . :.:: :.:: :::::
XP_016 GNFAAQMAGGFDEKAGGAQLGV--MQGPMGPMGPRGPPGPA---GAPGPQGFQGNPGEPG
160 170 180 190 200
210 220 230 240 250 260
pF1KB3 QAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRG
. : ::: :: : :: : : :::.:.::. :::: ::: : .: : ::.::.:::::
XP_016 EPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRG
210 220 230 240 250 260
270 280 290 300 310 320
pF1KB3 FDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARG
. : .: :::.::::.:::.: :::::.:::::::: :::::: : :::::::::: :
XP_016 YPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPG
270 280 290 300 310 320
330 340 350 360 370 380
pF1KB3 SDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPG
: ::: :: : ::::.::::::.::.:. : .:: : ::::: : : : : ::
XP_016 PAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPG
330 340 350 360 370 380
390 400 410 420 430 440
pF1KB3 INGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRG
.: ::.:: : :: ::::. : :::::: ::.: : .: .:::: : ::: ::.:
XP_016 TDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKG
390 400 410 420 430 440
450 460 470 480 490 500
pF1KB3 ERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAG
: : :: :.:: ::.:: :. ::::. : : ::::::: :: : .:. : :: :
XP_016 EPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPG
450 460 470 480 490 500
510 520 530 540 550 560
pF1KB3 ERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPG
::: : :::.:: :.::: : :: :: ::. : :: : .:: :: :. ::.:::::::
XP_016 ERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPG
510 520 530 540 550 560
570 580 590 600 610 620
pF1KB3 PSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGG
:.: :::::::::::::: .: ::: ::.: ::.:: .: :::.:::: :::::.::.:
XP_016 PQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAG
570 580 590 600 610 620
630 640 650 660 670 680
pF1KB3 DKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPG
..:. : :::.:.::::: :::::.::::. : :.::::: : .:. : ::::: ::
XP_016 ERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPG
630 640 650 660 670 680
690 700 710 720 730 740
pF1KB3 LAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPG
: : :: : :: .: :::.:: ::::: : :::::::::::. : :::::.:. :
XP_016 AQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVG
690 700 710 720 730 740
750 760 770 780 790 800
pF1KB3 GPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPG
: .:.::::: :: ::::::::::: :.::: : :: : :: ::.:::::::::::
XP_016 EKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPG
750 760 770 780 790 800
810 820 830 840 850 860
pF1KB3 PAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPG
:::: : :: .:.::.:::.: :.::..: :: :: :. :: :: : : :: ::. :
XP_016 PAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQG
810 820 830 840 850 860
870 880 890 900 910 920
pF1KB3 GPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAG
:::.::::: : :::::::::::::: : ::::: : :..: :: : : .: ::
XP_016 PPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAG
870 880 890 900 910 920
930 940 950 960 970 980
pF1KB3 QPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANG
::::: :: .:: :: :: : :..: ::..: ::. : :: :: : .:: :: :: :
XP_016 PPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPG
930 940 950 960 970 980
990 1000 1010 1020 1030 1040
pF1KB3 LSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPG
::.:::::: : :::.: ::::::.:.::.:: :::::. : ::::::.:. :::::::
XP_016 ASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPG
990 1000 1010 1020 1030 1040
1050 1060 1070 1080 1090 1100
pF1KB3 HPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKG
:: :::.::.::.:::::.: :: : ::::.:: :::::::::::.:: : :.::
XP_016 PPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKG
1050 1060 1070 1080 1090 1100
1110 1120 1130 1140 1150 1160
pF1KB3 HRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRG
:::: : : :: :::.:.::: : ::.::::: :: :: ::::..: :::::::::::
XP_016 HRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRG
1110 1120 1130 1140 1150 1160
1170 1180 1190 1200 1210 1220
pF1KB3 NRGERGSEGSPGHPGQPGPPGPPGAPGPCCGGVGAAAIAGIGGEKAGGFAPYY--GDEPM
:: : : ::.:: :::::: ::: :. .:.::.: .. : : .:.
XP_016 RSGETGPAGPPGNPG---PPGPPGPPGP---GIDMSAFAGLGPREKGPDPLQYMRADQAA
1170 1180 1190 1200 1210 1220
1230 1240 1250 1260 1270 1280
pF1KB3 D-FKINTDEIMTSLKSVNGQIESLISPDGSRKNPARNCRDLKFCHPELKSGEYWVDPNQG
.. . :. ..:::.:.::::. ::.::::::::.:::::.:::: :::.::.:::::
XP_016 GGLRQHDAEVDATLKSLNNQIESIRSPEGSRKNPARTCRDLKLCHPEWKSGDYWIDPNQG
1230 1240 1250 1260 1270 1280
1290 1300 1310 1320 1330 1340
pF1KB3 CKLDAIKVFCNMETGETCISANPLNVPRKHWWTDSSAEKKHVWFGESMDGGFQFSYGNPE
: :::.::::::::::::. :: :::.:.::...: ::::.::::...:::.::::. .
XP_016 CTLDAMKVFCNMETGETCVYPNPANVPKKNWWSSKSKEKKHIWFGETINGGFHFSYGDDN
1290 1300 1310 1320 1330 1340
1350 1360 1370 1380 1390 1400
pF1KB3 LPEDVLDVQLAFLRLLSSRASQNITYHCKNSIAYMDQASGNVKKALKLMGSNEGEFKAEG
: .. .::..::::::...::::::::::::::.:.:.::.:::: ..:::. :..:::
XP_016 LAPNTANVQMTFLRLLSTEGSQNITYHCKNSIAYLDEAAGNLKKALLIQGSNDVEIRAEG
1350 1360 1370 1380 1390 1400
1410 1420 1430 1440 1450 1460
pF1KB3 NSKFTYTVLEDGCTKHTGEWSKTVFEYRTRKAVRLPIVDIAPYDIGGPDQEFGVDVGPVC
::.::::.:.::::::::.:.:::.:::..:. ::::.::::.:::::.::::::.::::
XP_016 NSRFTYTALKDGCTKHTGKWGKTVIEYRSQKTSRLPIIDIAPMDIGGPEQEFGVDIGPVC
1410 1420 1430 1440 1450 1460
pF1KB3 FL
::
XP_016 FL
>>NP_001835 (OMIM: 108300,120140,132450,150600,151210,15 (1487 aa)
initn: 4885 init1: 4885 opt: 6371 Z-score: 2089.2 bits: 399.2 E(85289): 1.3e-109
Smith-Waterman score: 6681; 61.0% identity (74.9% similar) in 1504 aa overlap (1-1466:1-1487)
10 20 30 40 50
pF1KB3 MMSFVQKGSWLLLALLHPTIILAQQEAVE--GGCSHLGQSYADRDVWKPEPCQICVCDSG
:. . . .::.:: ... : . :. :.: . :: : :.::::::::.:::::.:
NP_001 MIRLGAPQTLVLLTLLVAAVLRCQGQDVQEAGSCVQDGQRYNDKDVWKPEPCRICVCDTG
10 20 30 40 50 60
60 70 80 90
pF1KB3 SVLCDDIICDDQELDCPNPEIPFGECCAVCP--------QP-P-------------TAPT
.::::::::.: . :: .::::::::: .:: :: : ..:
NP_001 TVLCDDIICEDVK-DCLSPEIPFGECCPICPTDLATASGQPGPKGQKGEPGDIKDIVGPK
70 80 90 100 110
100 110 120 130 140
pF1KB3 RPPNGQGP---QGPKGD------PGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTG
::. ::: :::.:: : :: ::.:.:: ::.:: :: ::::: : :
NP_001 GPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPG-----PPG
120 130 140 150 160 170
150 160 170 180 190 200
pF1KB3 -PQNYSPQY-DSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGE
:.. :. ..: :.: : :. . :: :: :: :::: . :.:: :.:: :::
NP_001 LGGNFAAQMAGGFDEKAGGAQLGV--MQGPMGPMGPRGPPGPA---GAPGPQGFQGNPGE
180 190 200 210 220
210 220 230 240 250 260
pF1KB3 PGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGH
::. : ::: :: : :: : : :::.:.::. :::: ::: : .: : ::.::.:::
NP_001 PGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGH
230 240 250 260 270 280
270 280 290 300 310 320
pF1KB3 RGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGA
::. : .: :::.::::.:::.: :::::.:::::::: :::::: : ::::::::::
NP_001 RGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQ
290 300 310 320 330 340
330 340 350 360 370 380
pF1KB3 RGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGP
: : ::: :: : ::::.::::::.::.:. : .:: : ::::: : : : :
NP_001 PGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGN
350 360 370 380 390 400
390 400 410 420 430 440
pF1KB3 PGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGP
:: .: ::.:: : :: ::::. : :::::: ::.: : .: .:::: : ::: ::
NP_001 PGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGP
410 420 430 440 450 460
450 460 470 480 490 500
pF1KB3 RGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGP
.:: : :: :.:: ::.:: :. ::::. : : ::::::: :: : .:. : ::
NP_001 KGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGA
470 480 490 500 510 520
510 520 530 540 550 560
pF1KB3 AGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGP
:::: : :::.:: :.::: : :: :: ::. : :: : .:: :: :. ::.:::::
NP_001 PGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGP
530 540 550 560 570 580
570 580 590 600 610 620
pF1KB3 PGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGP
:::.: :::::::::::::: .: ::: ::.: ::.:: .: :::.:::: :::::.::
NP_001 PGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGP
590 600 610 620 630 640
630 640 650 660 670 680
pF1KB3 GGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGP
.:..:. : :::.:.::::: :::::.::::. : :.::::: : .:. : :::::
NP_001 AGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGS
650 660 670 680 690 700
690 700 710 720 730 740
pF1KB3 PGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGE
:: : : :: : :: .: :::.:: ::::: : :::::::::::. : :::::.:.
NP_001 PGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGD
710 720 730 740 750 760
750 760 770 780 790 800
pF1KB3 PGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGP
: : .:.::::: :: ::::::::::: :.::: : :: : :: ::.:::::::::
NP_001 VGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGP
770 780 790 800 810 820
810 820 830 840 850 860
pF1KB3 PGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGS
:::::: : :: .:.::.:::.: :.::..: :: :: :. :: :: : : :: ::.
NP_001 PGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGA
830 840 850 860 870 880
870 880 890 900 910 920
pF1KB3 PGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGD
: :::.::::: : :::::::::::::: : ::::: : :..: :: : : .:
NP_001 QGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGP
890 900 910 920 930 940
930 940 950 960 970 980
pF1KB3 AGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGA
:: ::::: :: .:: :: :: : :..: ::..: ::. : :: :: : .:: :: ::
NP_001 AGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGA
950 960 970 980 990 1000
990 1000 1010 1020 1030 1040
pF1KB3 NGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGA
: ::.:::::: : :::.: ::::::.:.::.:: :::::. : ::::::.:. :::::
NP_001 PGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGA
1010 1020 1030 1040 1050 1060
1050 1060 1070 1080 1090 1100
pF1KB3 PGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGI
:: :: :::.::.::.:::::.: :: : ::::.:: :::::::::::.:: : :.
NP_001 PGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGL
1070 1080 1090 1100 1110 1120
1110 1120 1130 1140 1150 1160
pF1KB3 KGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGP
:::::: : : :: :::.:.::: : ::.::::: :: :: ::::..: :::::::::
NP_001 KGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGP
1130 1140 1150 1160 1170 1180
1170 1180 1190 1200 1210 1220
pF1KB3 RGNRGERGSEGSPGHPGQPGPPGPPGAPGPCCGGVGAAAIAGIGGEKAGGFAPYY--GDE
:: :: : : ::.:: :::::::: : :. .:.::.: .. : : .:.
NP_001 RGRSGETGPAGPPGNPGPPGPPGPPG---P---GIDMSAFAGLGPREKGPDPLQYMRADQ
1190 1200 1210 1220 1230 1240
1230 1240 1250 1260 1270 1280
pF1KB3 PMD-FKINTDEIMTSLKSVNGQIESLISPDGSRKNPARNCRDLKFCHPELKSGEYWVDPN
.. . :. ..:::.:.::::. ::.::::::::.:::::.:::: :::.::.:::
NP_001 AAGGLRQHDAEVDATLKSLNNQIESIRSPEGSRKNPARTCRDLKLCHPEWKSGDYWIDPN
1250 1260 1270 1280 1290 1300
1290 1300 1310 1320 1330 1340
pF1KB3 QGCKLDAIKVFCNMETGETCISANPLNVPRKHWWTDSSAEKKHVWFGESMDGGFQFSYGN
::: :::.::::::::::::. :: :::.:.::...: ::::.::::...:::.::::.
NP_001 QGCTLDAMKVFCNMETGETCVYPNPANVPKKNWWSSKSKEKKHIWFGETINGGFHFSYGD
1310 1320 1330 1340 1350 1360
1350 1360 1370 1380 1390 1400
pF1KB3 PELPEDVLDVQLAFLRLLSSRASQNITYHCKNSIAYMDQASGNVKKALKLMGSNEGEFKA
.: .. .::..::::::...::::::::::::::.:.:.::.:::: ..:::. :..:
NP_001 DNLAPNTANVQMTFLRLLSTEGSQNITYHCKNSIAYLDEAAGNLKKALLIQGSNDVEIRA
1370 1380 1390 1400 1410 1420
1410 1420 1430 1440 1450 1460
pF1KB3 EGNSKFTYTVLEDGCTKHTGEWSKTVFEYRTRKAVRLPIVDIAPYDIGGPDQEFGVDVGP
::::.::::.:.::::::::.:.:::.:::..:. ::::.::::.:::::.::::::.::
NP_001 EGNSRFTYTALKDGCTKHTGKWGKTVIEYRSQKTSRLPIIDIAPMDIGGPEQEFGVDIGP
1430 1440 1450 1460 1470 1480
pF1KB3 VCFL
::::
NP_001 VCFL
>>XP_016874318 (OMIM: 108300,120140,132450,150600,151210 (1534 aa)
initn: 4885 init1: 4885 opt: 6371 Z-score: 2089.0 bits: 399.2 E(85289): 1.3e-109
Smith-Waterman score: 6680; 61.4% identity (75.2% similar) in 1494 aa overlap (11-1466:58-1534)
10 20 30
pF1KB3 MMSFVQKGSWLLLALLHPTIILAQQEAVE--GGCSHLGQS
.::.:: ... : . :. :.: . ::
XP_016 RFLPGMKGGTGDQEKRPAKPWEEGSLAKTLVLLTLLVAAVLRCQGQDVQEAGSCVQDGQR
30 40 50 60 70 80
40 50 60 70 80 90
pF1KB3 YADRDVWKPEPCQICVCDSGSVLCDDIICDDQELDCPNPEIPFGECCAVCP--------Q
: :.::::::::.:::::.:.::::::::.: . :: .::::::::: .:: :
XP_016 YNDKDVWKPEPCRICVCDTGTVLCDDIICEDVK-DCLSPEIPFGECCPICPTDLATASGQ
90 100 110 120 130 140
100 110 120
pF1KB3 P-P-------------TAPTRPPNGQGP---QGPKGD------PGPPGIPGRNGDPGIPG
: : ..: ::. ::: :::.:: : :: ::.:.:: ::
XP_016 PGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPG
150 160 170 180 190 200
130 140 150 160 170 180
pF1KB3 QPGSPGSPGPPGICESCPTG-PQNYSPQY-DSYDVKSGVAVGGLAGYPGPAGPPGPPGPP
.:: :: ::::: : : :.. :. ..: :.: : :. . :: :: :: :::
XP_016 NPGPPGPPGPPG-----PPGLGGNFAAQMAGGFDEKAGGAQLGV--MQGPMGPMGPRGPP
210 220 230 240 250
190 200 210 220 230 240
pF1KB3 GTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLP
: .: .:: :.:: :::::. : ::: :: : :: : : :::.:.::. :::: :
XP_016 GPAG---APGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPP
260 270 280 290 300 310
250 260 270 280 290 300
pF1KB3 GPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAP
:: : .: : ::.::.:::::. : .: :::.::::.:::.: :::::.:::::::: :
XP_016 GPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLP
320 330 340 350 360 370
310 320 330 340 350 360
pF1KB3 GERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAP
::::: : :::::::::: : : ::: :: : ::::.::::::.::.:. : .::
XP_016 GERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQ
380 390 400 410 420 430
370 380 390 400 410 420
pF1KB3 GQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAP
: ::::: : : : : :: .: ::.:: : :: ::::. : :::::: ::.:
XP_016 GPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPL
440 450 460 470 480 490
430 440 450 460 470 480
pF1KB3 GLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGER
: .: .:::: : ::: ::.:: : :: :.:: ::.:: :. ::::. : : :::
XP_016 GPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGER
500 510 520 530 540 550
490 500 510 520 530 540
pF1KB3 GAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGP
:::: :: : .:. : :: :::: : :::.:: :.::: : :: :: ::. : ::
XP_016 GAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDA
560 570 580 590 600 610
550 560 570 580 590 600
pF1KB3 GSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQ
: .:: :: :. ::.::::::::.: :::::::::::::: .: ::: ::.: ::.:: .
XP_016 GPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLR
620 630 640 650 660 670
610 620 630 640 650 660
pF1KB3 GPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDA
: :::.:::: :::::.::.:..:. : :::.:.::::: :::::.::::. : :.:
XP_016 GLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEA
680 690 700 710 720 730
670 680 690 700 710 720
pF1KB3 GAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQ
:::: : .:. : ::::: :: : : :: : :: .: :::.:: ::::: : ::::
XP_016 GAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQ
740 750 760 770 780 790
730 740 750 760 770 780
pF1KB3 GMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAP
:::::::. : :::::.:. : : .:.::::: :: ::::::::::: :.::: : :
XP_016 GMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPP
800 810 820 830 840 850
790 800 810 820 830 840
pF1KB3 GLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPP
: : :: ::.::::::::::::::: : :: .:.::.:::.: :.::..: :: ::
XP_016 GPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPS
860 870 880 890 900 910
850 860 870 880 890 900
pF1KB3 GGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPP
:. :: :: : : :: ::. : :::.::::: : :::::::::::::: : :::::
XP_016 GAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPK
920 930 940 950 960 970
910 920 930 940 950 960
pF1KB3 GPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMP
: :..: :: : : .: :: ::::: :: .:: :: :: : :..: ::..: ::.
XP_016 GARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQR
980 990 1000 1010 1020 1030
970 980 990 1000 1010 1020
pF1KB3 GPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRD
: :: :: : .:: :: :: : ::.:::::: : :::.: ::::::.:.::.:: ::::
XP_016 GERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRD
1040 1050 1060 1070 1080 1090
1030 1040 1050 1060 1070 1080
pF1KB3 GSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAP
:. : ::::::.:. ::::::: :: :::.::.::.:::::.: :: : ::::.::
XP_016 GAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQ
1100 1110 1120 1130 1140 1150
1090 1100 1110 1120 1130 1140
pF1KB3 GPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPS
:::::::::::.:: : :.:::::: : : :: :::.:.::: : ::.::::: ::
XP_016 GPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPV
1160 1170 1180 1190 1200 1210
1150 1160 1170 1180 1190 1200
pF1KB3 GPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPCCGGVGAAAI
:: ::::..: ::::::::::: :: : : ::.:: :::::::: : :. .:.
XP_016 GPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPG-P-----GIDMSAF
1220 1230 1240 1250 1260 1270
1210 1220 1230 1240 1250 1260
pF1KB3 AGIGGEKAGGFAPYY--GDEPMD-FKINTDEIMTSLKSVNGQIESLISPDGSRKNPARNC
::.: .. : : .:. .. . :. ..:::.:.::::. ::.::::::::.:
XP_016 AGLGPREKGPDPLQYMRADQAAGGLRQHDAEVDATLKSLNNQIESIRSPEGSRKNPARTC
1280 1290 1300 1310 1320 1330
1270 1280 1290 1300 1310 1320
pF1KB3 RDLKFCHPELKSGEYWVDPNQGCKLDAIKVFCNMETGETCISANPLNVPRKHWWTDSSAE
::::.:::: :::.::.:::::: :::.::::::::::::. :: :::.:.::...: :
XP_016 RDLKLCHPEWKSGDYWIDPNQGCTLDAMKVFCNMETGETCVYPNPANVPKKNWWSSKSKE
1340 1350 1360 1370 1380 1390
1330 1340 1350 1360 1370 1380
pF1KB3 KKHVWFGESMDGGFQFSYGNPELPEDVLDVQLAFLRLLSSRASQNITYHCKNSIAYMDQA
:::.::::...:::.::::. .: .. .::..::::::...::::::::::::::.:.:
XP_016 KKHIWFGETINGGFHFSYGDDNLAPNTANVQMTFLRLLSTEGSQNITYHCKNSIAYLDEA
1400 1410 1420 1430 1440 1450
1390 1400 1410 1420 1430 1440
pF1KB3 SGNVKKALKLMGSNEGEFKAEGNSKFTYTVLEDGCTKHTGEWSKTVFEYRTRKAVRLPIV
.::.:::: ..:::. :..:::::.::::.:.::::::::.:.:::.:::..:. ::::.
XP_016 AGNLKKALLIQGSNDVEIRAEGNSRFTYTALKDGCTKHTGKWGKTVIEYRSQKTSRLPII
1460 1470 1480 1490 1500 1510
1450 1460
pF1KB3 DIAPYDIGGPDQEFGVDVGPVCFL
::::.:::::.::::::.::::::
XP_016 DIAPMDIGGPEQEFGVDIGPVCFL
1520 1530
>>XP_016874317 (OMIM: 108300,120140,132450,150600,151210 (1535 aa)
initn: 4885 init1: 4885 opt: 6370 Z-score: 2088.7 bits: 399.2 E(85289): 1.3e-109
Smith-Waterman score: 6678; 61.3% identity (75.1% similar) in 1495 aa overlap (11-1466:58-1535)
10 20 30
pF1KB3 MMSFVQKGSWLLLALLHPTIILAQQEAVE--GGCSHLGQS
.::.:: ... : . :. :.: . ::
XP_016 RFLPGMKGGTGDQEKRPAKPWEEGSLAKTLVLLTLLVAAVLRCQGQDVQEAGSCVQDGQR
30 40 50 60 70 80
40 50 60 70 80
pF1KB3 YADRDVWKPEPCQICVCDSGSVLCDDIICDDQELDCPNPEIPFGECCAVCP---------
: :.::::::::.:::::.:.::::::::.: . :: .::::::::: .::
XP_016 YNDKDVWKPEPCRICVCDTGTVLCDDIICEDVK-DCLSPEIPFGECCPICPTDLATASGW
90 100 110 120 130 140
90 100 110 120
pF1KB3 QP-P-------------TAPTRPPNGQGP---QGPKGD------PGPPGIPGRNGDPGIP
:: : ..: ::. ::: :::.:: : :: ::.:.:: :
XP_016 QPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTP
150 160 170 180 190 200
130 140 150 160 170 180
pF1KB3 GQPGSPGSPGPPGICESCPTG-PQNYSPQY-DSYDVKSGVAVGGLAGYPGPAGPPGPPGP
:.:: :: ::::: : : :.. :. ..: :.: : :. . :: :: :: ::
XP_016 GNPGPPGPPGPPG-----PPGLGGNFAAQMAGGFDEKAGGAQLGV--MQGPMGPMGPRGP
210 220 230 240 250
190 200 210 220 230 240
pF1KB3 PGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGL
:: .: .:: :.:: :::::. : ::: :: : :: : : :::.:.::. ::::
XP_016 PGPAG---APGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGP
260 270 280 290 300 310
250 260 270 280 290 300
pF1KB3 PGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGA
::: : .: : ::.::.:::::. : .: :::.::::.:::.: :::::.::::::::
XP_016 PGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGL
320 330 340 350 360 370
310 320 330 340 350 360
pF1KB3 PGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGA
:::::: : :::::::::: : : ::: :: : ::::.::::::.::.:. : .::
XP_016 PGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGA
380 390 400 410 420 430
370 380 390 400 410 420
pF1KB3 PGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGA
: ::::: : : : : :: .: ::.:: : :: ::::. : :::::: ::.:
XP_016 QGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGP
440 450 460 470 480 490
430 440 450 460 470 480
pF1KB3 PGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGE
: .: .:::: : ::: ::.:: : :: :.:: ::.:: :. ::::. : : ::
XP_016 LGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGE
500 510 520 530 540 550
490 500 510 520 530 540
pF1KB3 RGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGG
::::: :: : .:. : :: :::: : :::.:: :.::: : :: :: ::. : ::
XP_016 RGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGD
560 570 580 590 600 610
550 560 570 580 590 600
pF1KB3 PGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGP
: .:: :: :. ::.::::::::.: :::::::::::::: .: ::: ::.: ::.::
XP_016 AGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGL
620 630 640 650 660 670
610 620 630 640 650 660
pF1KB3 QGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGD
.: :::.:::: :::::.::.:..:. : :::.:.::::: :::::.::::. : :.
XP_016 RGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGE
680 690 700 710 720 730
670 680 690 700 710 720
pF1KB3 AGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGL
::::: : .:. : ::::: :: : : :: : :: .: :::.:: ::::: : :::
XP_016 AGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGL
740 750 760 770 780 790
730 740 750 760 770 780
pF1KB3 QGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGA
::::::::. : :::::.:. : : .:.::::: :: ::::::::::: :.::: :
XP_016 QGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGP
800 810 820 830 840 850
790 800 810 820 830 840
pF1KB3 PGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGP
:: : :: ::.::::::::::::::: : :: .:.::.:::.: :.::..: :: ::
XP_016 PGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGP
860 870 880 890 900 910
850 860 870 880 890 900
pF1KB3 PGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGP
:. :: :: : : :: ::. : :::.::::: : :::::::::::::: : :::::
XP_016 SGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGP
920 930 940 950 960 970
910 920 930 940 950 960
pF1KB3 PGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGM
: :..: :: : : .: :: ::::: :: .:: :: :: : :..: ::..: ::.
XP_016 KGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQ
980 990 1000 1010 1020 1030
970 980 990 1000 1010 1020
pF1KB3 PGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGR
: :: :: : .:: :: :: : ::.:::::: : :::.: ::::::.:.::.:: :::
XP_016 RGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGR
1040 1050 1060 1070 1080 1090
1030 1040 1050 1060 1070 1080
pF1KB3 DGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGA
::. : ::::::.:. ::::::: :: :::.::.::.:::::.: :: : ::::.::
XP_016 DGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGI
1100 1110 1120 1130 1140 1150
1090 1100 1110 1120 1130 1140
pF1KB3 PGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGP
:::::::::::.:: : :.:::::: : : :: :::.:.::: : ::.::::: ::
XP_016 QGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGP
1160 1170 1180 1190 1200 1210
1150 1160 1170 1180 1190 1200
pF1KB3 SGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPCCGGVGAAA
:: ::::..: ::::::::::: :: : : ::.:: :::::::: : :. .:
XP_016 VGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPG-P-----GIDMSA
1220 1230 1240 1250 1260 1270
1210 1220 1230 1240 1250 1260
pF1KB3 IAGIGGEKAGGFAPYY--GDEPMD-FKINTDEIMTSLKSVNGQIESLISPDGSRKNPARN
.::.: .. : : .:. .. . :. ..:::.:.::::. ::.::::::::.
XP_016 FAGLGPREKGPDPLQYMRADQAAGGLRQHDAEVDATLKSLNNQIESIRSPEGSRKNPART
1280 1290 1300 1310 1320 1330
1270 1280 1290 1300 1310 1320
pF1KB3 CRDLKFCHPELKSGEYWVDPNQGCKLDAIKVFCNMETGETCISANPLNVPRKHWWTDSSA
:::::.:::: :::.::.:::::: :::.::::::::::::. :: :::.:.::...:
XP_016 CRDLKLCHPEWKSGDYWIDPNQGCTLDAMKVFCNMETGETCVYPNPANVPKKNWWSSKSK
1340 1350 1360 1370 1380 1390
1330 1340 1350 1360 1370 1380
pF1KB3 EKKHVWFGESMDGGFQFSYGNPELPEDVLDVQLAFLRLLSSRASQNITYHCKNSIAYMDQ
::::.::::...:::.::::. .: .. .::..::::::...::::::::::::::.:.
XP_016 EKKHIWFGETINGGFHFSYGDDNLAPNTANVQMTFLRLLSTEGSQNITYHCKNSIAYLDE
1400 1410 1420 1430 1440 1450
1390 1400 1410 1420 1430 1440
pF1KB3 ASGNVKKALKLMGSNEGEFKAEGNSKFTYTVLEDGCTKHTGEWSKTVFEYRTRKAVRLPI
:.::.:::: ..:::. :..:::::.::::.:.::::::::.:.:::.:::..:. ::::
XP_016 AAGNLKKALLIQGSNDVEIRAEGNSRFTYTALKDGCTKHTGKWGKTVIEYRSQKTSRLPI
1460 1470 1480 1490 1500 1510
1450 1460
pF1KB3 VDIAPYDIGGPDQEFGVDVGPVCFL
.::::.:::::.::::::.::::::
XP_016 IDIAPMDIGGPEQEFGVDIGPVCFL
1520 1530
>>XP_016874320 (OMIM: 108300,120140,132450,150600,151210 (1305 aa)
initn: 4885 init1: 4885 opt: 6151 Z-score: 2018.6 bits: 385.9 E(85289): 1.1e-105
Smith-Waterman score: 6151; 63.4% identity (77.0% similar) in 1312 aa overlap (158-1466:5-1305)
130 140 150 160 170 180
pF1KB3 QPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGT
.: :.: : :. . :: :: :: ::::
XP_016 MAGGFDEKAGGAQLGV--MQGPMGPMGPRGPPGP
10 20 30
190 200 210 220 230 240
pF1KB3 SGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGP
.: .:: :.:: :::::. : ::: :: : :: : : :::.:.::. :::: :::
XP_016 AG---APGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGP
40 50 60 70 80
250 260 270 280 290 300
pF1KB3 PGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGE
: .: : ::.::.:::::. : .: :::.::::.:::.: :::::.:::::::: :::
XP_016 QGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGE
90 100 110 120 130 140
310 320 330 340 350 360
pF1KB3 RGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQ
::: : :::::::::: : : ::: :: : ::::.::::::.::.:. : .:: :
XP_016 RGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGP
150 160 170 180 190 200
370 380 390 400 410 420
pF1KB3 RGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGL
::::: : : : : :: .: ::.:: : :: ::::. : :::::: ::.: :
XP_016 RGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGP
210 220 230 240 250 260
430 440 450 460 470 480
pF1KB3 RGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGA
.: .:::: : ::: ::.:: : :: :.:: ::.:: :. ::::. : : :::::
XP_016 KGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGA
270 280 290 300 310 320
490 500 510 520 530 540
pF1KB3 PGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGS
:: :: : .:. : :: :::: : :::.:: :.::: : :: :: ::. : :: :
XP_016 PGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGP
330 340 350 360 370 380
550 560 570 580 590 600
pF1KB3 DGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGP
.:: :: :. ::.::::::::.: :::::::::::::: .: ::: ::.: ::.:: .:
XP_016 QGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGL
390 400 410 420 430 440
610 620 630 640 650 660
pF1KB3 PGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGA
:::.:::: :::::.::.:..:. : :::.:.::::: :::::.::::. : :.:::
XP_016 PGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGA
450 460 470 480 490 500
670 680 690 700 710 720
pF1KB3 PGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGM
:: : .:. : ::::: :: : : :: : :: .: :::.:: ::::: : ::::::
XP_016 PGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGM
510 520 530 540 550 560
730 740 750 760 770 780
pF1KB3 PGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGL
:::::. : :::::.:. : : .:.::::: :: ::::::::::: :.::: : ::
XP_016 PGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGP
570 580 590 600 610 620
790 800 810 820 830 840
pF1KB3 PGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGG
: :: ::.::::::::::::::: : :: .:.::.:::.: :.::..: :: :: :.
XP_016 AGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGA
630 640 650 660 670 680
850 860 870 880 890 900
pF1KB3 SGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGP
:: :: : : :: ::. : :::.::::: : :::::::::::::: : ::::: :
XP_016 PGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGA
690 700 710 720 730 740
910 920 930 940 950 960
pF1KB3 AGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGP
:..: :: : : .: :: ::::: :: .:: :: :: : :..: ::..: ::. :
XP_016 RGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGE
750 760 770 780 790 800
970 980 990 1000 1010 1020
pF1KB3 RGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGS
:: :: : .:: :: :: : ::.:::::: : :::.: ::::::.:.::.:: :::::.
XP_016 RGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGA
810 820 830 840 850 860
1030 1040 1050 1060 1070 1080
pF1KB3 PGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGP
: ::::::.:. ::::::: :: :::.::.::.:::::.: :: : ::::.:: ::
XP_016 AGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGP
870 880 890 900 910 920
1090 1100 1110 1120 1130 1140
pF1KB3 QGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGP
:::::::::.:: : :.:::::: : : :: :::.:.::: : ::.::::: :: ::
XP_016 QGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGP
930 940 950 960 970 980
1150 1160 1170 1180 1190 1200
pF1KB3 PGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPCCGGVGAAAIAG
::::..: ::::::::::: :: : : ::.:: :::::::: :: . .:.::
XP_016 SGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPG-PG-----IDMSAFAG
990 1000 1010 1020 1030 1040
1210 1220 1230 1240 1250 1260
pF1KB3 IGGEKAGGFAPYY--GDEPMD-FKINTDEIMTSLKSVNGQIESLISPDGSRKNPARNCRD
.: .. : : .:. .. . :. ..:::.:.::::. ::.::::::::.:::
XP_016 LGPREKGPDPLQYMRADQAAGGLRQHDAEVDATLKSLNNQIESIRSPEGSRKNPARTCRD
1050 1060 1070 1080 1090 1100
1270 1280 1290 1300 1310 1320
pF1KB3 LKFCHPELKSGEYWVDPNQGCKLDAIKVFCNMETGETCISANPLNVPRKHWWTDSSAEKK
::.:::: :::.::.:::::: :::.::::::::::::. :: :::.:.::...: :::
XP_016 LKLCHPEWKSGDYWIDPNQGCTLDAMKVFCNMETGETCVYPNPANVPKKNWWSSKSKEKK
1110 1120 1130 1140 1150 1160
1330 1340 1350 1360 1370 1380
pF1KB3 HVWFGESMDGGFQFSYGNPELPEDVLDVQLAFLRLLSSRASQNITYHCKNSIAYMDQASG
:.::::...:::.::::. .: .. .::..::::::...::::::::::::::.:.:.:
XP_016 HIWFGETINGGFHFSYGDDNLAPNTANVQMTFLRLLSTEGSQNITYHCKNSIAYLDEAAG
1170 1180 1190 1200 1210 1220
1390 1400 1410 1420 1430 1440
pF1KB3 NVKKALKLMGSNEGEFKAEGNSKFTYTVLEDGCTKHTGEWSKTVFEYRTRKAVRLPIVDI
:.:::: ..:::. :..:::::.::::.:.::::::::.:.:::.:::..:. ::::.::
XP_016 NLKKALLIQGSNDVEIRAEGNSRFTYTALKDGCTKHTGKWGKTVIEYRSQKTSRLPIIDI
1230 1240 1250 1260 1270 1280
1450 1460
pF1KB3 APYDIGGPDQEFGVDVGPVCFL
::.:::::.::::::.::::::
XP_016 APMDIGGPEQEFGVDIGPVCFL
1290 1300
>>XP_011522643 (OMIM: 114000,120150,130000,130060,166200 (1398 aa)
initn: 7372 init1: 4339 opt: 5691 Z-score: 1869.1 bits: 358.4 E(85289): 2.3e-97
Smith-Waterman score: 6176; 59.1% identity (71.1% similar) in 1487 aa overlap (1-1466:1-1398)
10 20 30 40
pF1KB3 MMSFVQKGSWLLLALLHPTIILA--QQEA-VEGG--------CSHLGQSYADRDVWKPEP
:.::: . :: :: : .:. :.:. ::: : . : : :::::::::
XP_011 MFSFV---DLRLLLLLAATALLTHGQEEGQVEGQDEDIPPITCVQNGLRYHDRDVWKPEP
10 20 30 40 50
50 60 70 80 90 100
pF1KB3 CQICVCDSGSVLCDDIICDDQELDCPNPEIPFGECCAVCPQPPTAPT-RPPNG-QGPQG-
:.:::::.:.:::::.:::. . .::. :.: :::: :::. .:: . .: .::.:
XP_011 CRICVCDNGKVLCDDVICDETK-NCPGAEVPEGECCPVCPDGSESPTDQETTGVEGPKGD
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB3 --PKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTG-PQNYSPQYD-SYDVKS
:.: :: : :::.: :: :: :: :: ::::: : : :..:: . .:: ::
XP_011 TGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPG-----PPGLGGNFAPQLSYGYDEKS
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB3 GVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIG
.::.. ::: :: :: : :: ::.:: :.::::::::. : ::: :: : :
XP_011 ---TGGIS-VPGPMGPSGPRGLPGP---PGAPGPQGFQGPPGEPGEPGASGPMGPRGPPG
180 190 200 210 220
230 240 250 260 270 280
pF1KB3 PSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPG
: : : :::.:.:::::::: ::: : .: : :.:::::::::.: .: ::..: :
XP_011 PPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAG
230 240 250 260 270 280
290 300 310 320 330 340
pF1KB3 LKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAG
::: : :::::::: ::::: :::::::: ::
XP_011 PKGEPGSPGENGAPGQMGPRGLPGERGRPGAPG---------------------------
290 300 310
350 360 370 380 390 400
pF1KB3 FPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAG
:::.::..: :: .: ::.::
XP_011 ------------PAGNPGADGQPGAKGA------------------NGAPG---------
320 330
410 420 430 440 450 460
pF1KB3 IPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKG
: ::::. ::::: :: : .: :: .:..:::: :.::. : .:: : .:. : :: :
XP_011 IAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAG
340 350 360 370 380 390
470 480 490 500 510 520
pF1KB3 EDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAG
:.:: :. :::: .:::: ::::.:: :: : .:. : ::::::::.::::::.:. :
XP_011 EEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPG
400 410 420 430 440 450
530 540 550 560 570 580
pF1KB3 EPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPG
: :: : : :: .:. ::::.:: ::: :::: :..:::::::: : ::: :::::::
XP_011 EAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPG
460 470 480 490 500 510
590 600 610 620 630 640
pF1KB3 PKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQG
::: : ::: :::: :: :: :: ::.::.: ::::::.::.:..:. :: : :.::
XP_011 PKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQG
520 530 540 550 560 570
650 660 670 680 690 700
pF1KB3 LPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPG
::: .::::: ::::: : :: :::: :..:. : ::::: : : : ::. : ::
XP_011 LPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPG
580 590 600 610 620 630
710 720 730 740 750 760
pF1KB3 PEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRG
.:.:: :: :: ::. :.:::::::::::. : ::::::.:. : :::: ::::: ::
XP_011 NDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRG
640 650 660 670 680 690
770 780 790 800 810 820
pF1KB3 PTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPG
::::::::::: ::::::.: : : .: ::.::.::: :::::::: : :: .:.::
XP_011 LTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPG
700 710 720 730 740 750
830 840 850 860 870 880
pF1KB3 GKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPG
.::: : : ::..:::: ::: : :: : : :.:: ::: : :::.::::: : :
XP_011 AKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVG
760 770 780 790 800 810
890 900 910 920 930 940
pF1KB3 PPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPG
::: .:: ::::: : ::.: :: :.:: : :: :: : : ::::::::.:: :
XP_011 PPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAG
820 830 840 850 860 870
950 960 970 980 990 1000
pF1KB3 APGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPG
::: : ::.: ::..: ::. : :: :: : .:: :: : .: :::::::::.: ::
XP_011 APGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPG
880 890 900 910 920 930
1010 1020 1030 1040 1050 1060
pF1KB3 LAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSG
::: :: ::.: ::..: ::::::::.::::::.: : ::::: :: :::::::::::
XP_011 LAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSG
940 950 960 970 980 990
1070 1080 1090 1100 1110 1120
pF1KB3 DRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPG
::::.::::::: ::.:.:: ::::::::::::::.: :::::::: : : :: ::
XP_011 DRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPG
1000 1010 1020 1030 1040 1050
1130 1140 1150 1160 1170 1180
pF1KB3 PAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPG
:.:: :. :::::::: : .: ::::: .: ::::::::::: :. : : :: ::
XP_011 SPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPG
1060 1070 1080 1090 1100 1110
1190 1200 1210 1220 1230 1240
pF1KB3 QPGPPGPPGAPGPCCGGVGAAAIAGIGGEKAGGFAPYYGDEPMDFKINTD-EIMTSLKSV
:::::::.: : . . ::: . :: . . . : :. :.:::.
XP_011 PPGPPGPPSA------GFDFSFLPQPPQEKAHDGGRYYRADDANVVRDRDLEVDTTLKSL
1120 1130 1140 1150 1160 1170
1250 1260 1270 1280 1290 1300
pF1KB3 NGQIESLISPDGSRKNPARNCRDLKFCHPELKSGEYWVDPNQGCKLDAIKVFCNMETGET
. :::.. ::.::::::::.:::::.:: . ::::::.::::::.:::::::::::::::
XP_011 SQQIENIRSPEGSRKNPARTCRDLKMCHSDWKSGEYWIDPNQGCNLDAIKVFCNMETGET
1180 1190 1200 1210 1220 1230
1310 1320 1330 1340 1350
pF1KB3 CISANPLNVPRKHWW-TDSSAEKKHVWFGESMDGGFQFSYGNP-ELPEDVLDVQLAFLRL
:. . .: .:.:. . . .:.:::::::: :::: ::. : :: .::.::::
XP_011 CVYPTQPSVAQKNWYISKNPKDKRHVWFGESMTDGFQFEYGGQGSDPADVA-IQLTFLRL
1240 1250 1260 1270 1280 1290
1360 1370 1380 1390 1400 1410
pF1KB3 LSSRASQNITYHCKNSIAYMDQASGNVKKALKLMGSNEGEFKAEGNSKFTYTVLEDGCTK
.:..::::::::::::.::::: .::.:::: :.:::: :..:::::.:::.: ::::.
XP_011 MSTEASQNITYHCKNSVAYMDQQTGNLKKALLLQGSNEIEIRAEGNSRFTYSVTVDGCTS
1300 1310 1320 1330 1340 1350
1420 1430 1440 1450 1460
pF1KB3 HTGEWSKTVFEYRTRKAVRLPIVDIAPYDIGGPDQEFGVDVGPVCFL
::: :.:::.::.: :. ::::.:.:: :.:.:::::: ::::::::
XP_011 HTGAWGKTVIEYKTTKTSRLPIIDVAPLDVGAPDQEFGFDVGPVCFL
1360 1370 1380 1390
>>XP_011508875 (OMIM: 120190,130000) PREDICTED: collagen (1453 aa)
initn: 9022 init1: 4379 opt: 5609 Z-score: 1842.4 bits: 353.5 E(85289): 7e-96
Smith-Waterman score: 5826; 55.5% identity (70.3% similar) in 1466 aa overlap (39-1466:2-1453)
10 20 30 40 50 60
pF1KB3 SWLLLALLHPTIILAQQEAVEGGCSHLGQSYADRDVWKPEPCQICVCDSGSVLCDDIICD
: .::.::: ::::::::.:..::: : :.
XP_011 MYLNRDIWKPAPCQICVCDNGAILCDKIECQ
10 20 30
70 80 90
pF1KB3 DQELDCPNPEIPFGECCAVCPQPP------------------------------TAPTRP
: ::: .: : :::: :: : : .:. :
XP_011 DV-LDCADPVTPPGECCPVCSQTPGGGNTNFGRGRKGQKGEPGLVPVVTGIRGRPGPAGP
40 50 60 70 80 90
100 110 120 130 140 150
pF1KB3 PNGQGPQG---PKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTG-PQNYSPQ
:..:::.: ::: ::: : : .:.::.:::::.:: :: :. . : : . .: :
XP_011 PGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPS--HPGPDGLSRPFSAQ
100 110 120 130 140
160 170 180 190 200 210
pF1KB3 YDSYDVKSGVAVGGLAG-YPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSG
. . : ::: .:. .: .:: .:: :: :: : .:. :. : : :::::::. :: :
XP_011 MAGLDEKSG--LGSQVGLMPGSVGPVGPRGPQGLQGQQGGAG-P--TGPPGEPGDPGPMG
150 160 170 180 190 200
220 230 240 250 260 270
pF1KB3 PPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNG
: : : :: : :.::: :: : ::: :. : :: .: : ::.::.::::: : .:
XP_011 PIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEG
210 220 230 240 250 260
280 290 300 310 320 330
pF1KB3 EKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPG
:::.:::: ::: : : :: ::.:::: :::::: : :: : :: : :. : :
XP_011 PKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMG
270 280 290 300 310 320
340 350 360 370 380 390
pF1KB3 PPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPG
: : ::..::::.:: :::.::.:. : .: ::::: :: : .:. : :: : .:.::
XP_011 PLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPG
330 340 350 360 370 380
400 410 420 430 440 450
pF1KB3 GKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAG
.:: : : : :: : : ::: :..: :.:: :.:: : ::: ::.:: : :
XP_011 AKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHG
390 400 410 420 430 440
460 470 480 490 500 510
pF1KB3 IPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPG
: : : ::.:: : :.::. : :: .::::::: :: : .:.:: :: :::: :
XP_011 IQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVG
450 460 470 480 490 500
520 530 540 550 560 570
pF1KB3 PAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRG
.::.:. :.::: : :: :: ::. :.:: : .:: :: :. ::.::::::: : ::
XP_011 SSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRG
510 520 530 540 550 560
580 590 600 610 620 630
pF1KB3 QPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTG
::: ::.:::::..: ::: :: :. : :: .: :::.::.::.:: :: : .:..:. :
XP_011 QPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQG
570 580 590 600 610 620
640 650 660 670 680 690
pF1KB3 PPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPG
:::: :.::::: :::::.::::. : :: :: : : .:. : ::::: ::..: ::
XP_011 PPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPG
630 640 650 660 670 680
700 710 720 730 740 750
pF1KB3 LRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADG
.: :: ::.: ::. :: : :: .: ::::::::::: :.::::::.: : ::.:
XP_011 EKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEG
690 700 710 720 730 740
760 770 780 790 800 810
pF1KB3 VPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPG
. :.:: :: ::.::::::: :.::: : :: : : ::.:: :::.:: : .:: :
XP_011 TAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAG
750 760 770 780 790 800
820 830 840 850 860 870
pF1KB3 APGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAG
: .:.:: ::: : ::.::..: :: : :. :: :: : :.:: ::. : :::.:
XP_011 PQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATG
810 820 830 840 850 860
880 890 900 910 920 930
pF1KB3 FPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKG
:::. : :::: : ::: :: : :::.:::: :. :. : : :: : : ::.::
XP_011 FPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKG
870 880 890 900 910 920
940 950 960 970 980 990
pF1KB3 SPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERG
.:: .: :: :: : :: :: ::..: ::. : :: :: : : :: : .: .:..:
XP_011 DPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKG
930 940 950 960 970 980
1000 1010 1020 1030 1040 1050
pF1KB3 PPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPG
:::: : :: : .:::: .: :.:: :::::. : .::::. : : ::. : :: ::
XP_011 PPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPG
990 1000 1010 1020 1030 1040
1060 1070 1080 1090 1100 1110
pF1KB3 PVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPG
::: : .:.::. : :: : :: ::.:: :::::::::::. :.:: : :::::: :
XP_011 PVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTG
1050 1060 1070 1080 1090 1100
1120 1130 1140 1150 1160 1170
pF1KB3 NPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERG
: :: ::: :.::. : ::: ::::: :: :: ::.:. : ::::::: ::. :: :
XP_011 LQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAG
1110 1120 1130 1140 1150 1160
1180 1190 1200 1210 1220 1230
pF1KB3 SEGSPGHPGQPGPPGPPGAPGPCCGGVGAAAIAGIGGEKAGGFAPYYGDEPM--DFKINT
:: : ::.:::::::: :: ...: : : :. : . .. : : .:
XP_011 PEG-P--PGEPGPPGPPGPPGHLTAALG--DIMGHYDESMPDPLPEFTEDQAAPDDKNKT
1170 1180 1190 1200 1210
1240 1250 1260 1270 1280 1290
pF1KB3 DE-IMTSLKSVNGQIESLISPDGSRKNPARNCRDLKFCHPELKSGEYWVDPNQGCKLDAI
: . ..:::...:::.. :::::.:.:::.: :::.:: .:::::.::::: :::
XP_011 DPGVHATLKSLSSQIETMRSPDGSKKHPARTCDDLKLCHSAKQSGEYWIDPNQGSVEDAI
1220 1230 1240 1250 1260 1270
1300 1310 1320 1330 1340 1350
pF1KB3 KVFCNMETGETCISANPLNVPRKHWWTDSSAEKKHVWFGESMDGGFQFSYGNPELPEDVL
::.:::::::::::::: .:::: ::...: ..: ::.: .:. : ::.::. . :. ..
XP_011 KVYCNMETGETCISANPSSVPRKTWWASKSPDNKPVWYGLDMNRGSQFAYGDHQSPNTAI
1280 1290 1300 1310 1320 1330
1360 1370 1380 1390 1400 1410
pF1KB3 DVQLAFLRLLSSRASQNITYHCKNSIAYMDQASGNVKKALKLMGSNEGEFKAEGNSKFTY
.:..::::::..::::::: ::::..:::. . :.:::. : :.:. ..::::: .: :
XP_011 -TQMTFLRLLSKEASQNITYICKNSVGYMDDQAKNLKKAVVLKGANDLDIKAEGNIRFRY
1340 1350 1360 1370 1380 1390
1420 1430 1440 1450 1460
pF1KB3 TVLEDGCTKHTGEWSKTVFEYRTRKAVRLPIVDIAPYDIGGPDQEFGVDVGPVCFL
::.: :.:..:. .::::::::....::::.:.:: :.:: ::::::..:::::.
XP_011 IVLQDTCSKRNGNVGKTVFEYRTQNVARLPIIDLAPVDVGGTDQEFGVEIGPVCFV
1400 1410 1420 1430 1440 1450
1466 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 22:50:39 2016 done: Wed Nov 2 22:50:42 2016
Total Scan time: 20.730 Total Display time: 0.660
Function used was FASTA [36.3.4 Apr, 2011]