Result of FASTA (omim) for pF1KB3038
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB3038, 1401 aa
  1>>>pF1KB3038 1401 - 1401 aa - 1401 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 10.8711+/-0.000415; mu= -3.5020+/- 0.026
 mean_var=252.5029+/-52.357, 0's: 0 Z-trim(118.9): 123  B-trim: 0 in 0/56
 Lambda= 0.080713
 statistics sampled from 32176 (32303) to 32176 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.697), E-opt: 0.2 (0.379), width:  16
 Scan time: 14.100

The best scores are:                                      opt bits E(85289)
NP_066963 (OMIM: 147920,300128,300867) lysine-spec (1401) 9483 1118.6       0
NP_001278345 (OMIM: 147920,300128,300867) lysine-s (1408) 9167 1081.8       0
XP_011542266 (OMIM: 147920,300128,300867) PREDICTE (1437) 8764 1034.9       0
XP_011542276 (OMIM: 147920,300128,300867) PREDICTE (1293) 8752 1033.5       0
XP_011542269 (OMIM: 147920,300128,300867) PREDICTE (1420) 8669 1023.8       0
XP_011542265 (OMIM: 147920,300128,300867) PREDICTE (1444) 8448 998.1       0
XP_016885271 (OMIM: 147920,300128,300867) PREDICTE (1427) 8347 986.3       0
XP_011529751 (OMIM: 400009) PREDICTED: histone dem (1530) 8143 962.6       0
NP_001245181 (OMIM: 400009) histone demethylase UT (1392) 8136 961.8       0
XP_016885556 (OMIM: 400009) PREDICTED: histone dem (1387) 8121 960.0       0
XP_011542264 (OMIM: 147920,300128,300867) PREDICTE (1456) 7950 940.1       0
XP_011529749 (OMIM: 400009) PREDICTED: histone dem (1537) 7843 927.7       0
NP_001245187 (OMIM: 400009) histone demethylase UT (1399) 7836 926.8       0
NP_001245185 (OMIM: 400009) histone demethylase UT (1335) 7789 921.3       0
XP_011542263 (OMIM: 147920,300128,300867) PREDICTE (1463) 7628 902.6       0
NP_001245190 (OMIM: 400009) histone demethylase UT (1389) 7061 836.6       0
XP_011529750 (OMIM: 400009) PREDICTED: histone dem (1531) 6941 822.6       0
XP_011542273 (OMIM: 147920,300128,300867) PREDICTE (1393) 6904 818.3       0
XP_016885273 (OMIM: 147920,300128,300867) PREDICTE (1193) 6794 805.5       0
XP_005262575 (OMIM: 400009) PREDICTED: histone dem (1182) 6762 801.7       0
NP_001278346 (OMIM: 147920,300128,300867) lysine-s (1356) 6582 780.8       0
XP_011542275 (OMIM: 147920,300128,300867) PREDICTE (1375) 6563 778.6       0
NP_001278350 (OMIM: 147920,300128,300867) lysine-s (1105) 6545 776.5       0
NP_001278344 (OMIM: 147920,300128,300867) lysine-s (1453) 6543 776.3       0
XP_011542262 (OMIM: 147920,300128,300867) PREDICTE (1472) 6543 776.3       0
NP_001245193 (OMIM: 400009) histone demethylase UT (1376) 6275 745.1 8.6e-214
XP_005272716 (OMIM: 147920,300128,300867) PREDICTE (1367) 6269 744.4 1.4e-213
XP_011542267 (OMIM: 147920,300128,300867) PREDICTE (1429) 6185 734.6 1.3e-210
XP_016885272 (OMIM: 147920,300128,300867) PREDICTE (1374) 6165 732.2 6.1e-210
XP_016885274 (OMIM: 147920,300128,300867) PREDICTE (1071) 6089 723.4 2.3e-207
NP_001278347 (OMIM: 147920,300128,300867) lysine-s (1322) 6089 723.4 2.7e-207
XP_005272713 (OMIM: 147920,300128,300867) PREDICTE (1419) 6089 723.4 2.9e-207
NP_001245195 (OMIM: 400009) histone demethylase UT (1367) 5982 710.9 1.6e-203
XP_011529766 (OMIM: 400009) PREDICTED: histone dem (1124) 5865 697.3 1.7e-199
XP_011542274 (OMIM: 147920,300128,300867) PREDICTE (1392) 5863 697.1 2.4e-199
XP_011542270 (OMIM: 147920,300128,300867) PREDICTE (1411) 5844 694.9 1.1e-198
XP_011542277 (OMIM: 147920,300128,300867) PREDICTE (1238) 5824 692.5  5e-198
XP_011542260 (OMIM: 147920,300128,300867) PREDICTE (1489) 5824 692.6 5.9e-198
XP_011542259 (OMIM: 147920,300128,300867) PREDICTE (1508) 5824 692.6  6e-198
XP_011542272 (OMIM: 147920,300128,300867) PREDICTE (1403) 5550 660.6 2.3e-188
XP_011542268 (OMIM: 147920,300128,300867) PREDICTE (1422) 5528 658.1 1.3e-187
XP_011542271 (OMIM: 147920,300128,300867) PREDICTE (1410) 5446 648.5  1e-184
XP_011529754 (OMIM: 400009) PREDICTED: histone dem (1485) 5399 643.1 4.7e-183
XP_011529752 (OMIM: 400009) PREDICTED: histone dem (1515) 5399 643.1 4.7e-183
NP_001245188 (OMIM: 400009) histone demethylase UT (1331) 5394 642.5 6.3e-183
XP_011529744 (OMIM: 400009) PREDICTED: histone dem (1582) 5395 642.6 6.8e-183
NP_001245194 (OMIM: 400009) histone demethylase UT (1264) 5392 642.2 7.1e-183
NP_009056 (OMIM: 400009) histone demethylase UTY i (1347) 5392 642.2 7.5e-183
NP_001245189 (OMIM: 400009) histone demethylase UT (1377) 5392 642.2 7.7e-183
XP_011529760 (OMIM: 400009) PREDICTED: histone dem (1422) 5388 641.8 1.1e-182


>>NP_066963 (OMIM: 147920,300128,300867) lysine-specific  (1401 aa)
 initn: 9483 init1: 9483 opt: 9483  Z-score: 5978.0  bits: 1118.6 E(85289):    0
Smith-Waterman score: 9483; 100.0% identity (100.0% similar) in 1401 aa overlap (1-1401:1-1401)

               10        20        30        40        50        60
pF1KB3 MKSCGVSLATAAAAAAAFGDEEKKMAAGKASGESEEASPSLTAEEREALGGLDSRLFGFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 MKSCGVSLATAAAAAAAFGDEEKKMAAGKASGESEEASPSLTAEEREALGGLDSRLFGFV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 RFHEDGARTKALLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYPKALSAYQRYY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 RFHEDGARTKALLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYPKALSAYQRYY
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 SLQSDYWKNAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDPSFCRAKEIHLRLGLMFKVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 SLQSDYWKNAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDPSFCRAKEIHLRLGLMFKVN
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 TDYESSLKHFQLALVDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLSAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 TDYESSLKHFQLALVDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLSAQ
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 VKATVLQQLGWMHHTVDLLGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 VKATVLQQLGWMHHTVDLLGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKV
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 QDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 QDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGT
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 LYESCNQPQDAIKCYLNATRSKSCSNTSALAARIKYLQAQLCNLPQGSLQNKTKLLPSIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 LYESCNQPQDAIKCYLNATRSKSCSNTSALAARIKYLQAQLCNLPQGSLQNKTKLLPSIE
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 EAWSLPIPAELTSRQGAMNTAQQNTSDNWSGGHAVSHPPVQQQAHSWCLTPQKLQHLEQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 EAWSLPIPAELTSRQGAMNTAQQNTSDNWSGGHAVSHPPVQQQAHSWCLTPQKLQHLEQL
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB3 RANRNNLNPAQKLMLEQLESQFVLMQQHQMRPTGVAQVRSTGIPNGPTADSSLPTNSVSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 RANRNNLNPAQKLMLEQLESQFVLMQQHQMRPTGVAQVRSTGIPNGPTADSSLPTNSVSG
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB3 QQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAGHVPCSTSRTLGSTDTILIGNNHITG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 QQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAGHVPCSTSRTLGSTDTILIGNNHITG
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB3 SGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNSTQGLHKGQSSHSAGPNGERPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 SGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNSTQGLHKGQSSHSAGPNGERPL
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB3 SSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALNHLSSHTATSGGQQGITLTKESKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 SSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALNHLSSHTATSGGQQGITLTKESKP
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB3 SGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCSPSHGDSKSPGLLSSDNPQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 SGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCSPSHGDSKSPGLLSSDNPQL
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB3 SALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSSAISTATPSPKSTEQTTTNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 SALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSSAISTATPSPKSTEQTTTNS
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB3 VTSLNSPHSGLHTINGEGMEESQSPMKTDLLLVNHKPSPQIIPSMSVSIYPSSAEVLKAC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 VTSLNSPHSGLHTINGEGMEESQSPMKTDLLLVNHKPSPQIIPSMSVSIYPSSAEVLKAC
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB3 RNLGKNGLSNSSILLDKCPPPRPPSSPYPPLPKDKLNPPTPSIYLENKRDAFFPPLHQFC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 RNLGKNGLSNSSILLDKCPPPRPPSSPYPPLPKDKLNPPTPSIYLENKRDAFFPPLHQFC
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KB3 TNPNNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWDPTGTKKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 TNPNNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWDPTGTKKI
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KB3 WHCESNRSHTTIAKYAQYQASSFQESLREENEKRSHHKDHSDSESTSSDNSGRRRKGPFK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 WHCESNRSHTTIAKYAQYQASSFQESLREENEKRSHHKDHSDSESTSSDNSGRRRKGPFK
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KB3 TIKFGTNIDLSDDKKWKLQLHELTKLPAFVRVVSAGNLLSHVGHTILGMNTVQLYMKVPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 TIKFGTNIDLSDDKKWKLQLHELTKLPAFVRVVSAGNLLSHVGHTILGMNTVQLYMKVPG
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KB3 SRTPGHQENNNFCSVNINIGPGDCEWFVVPEGYWGVLNDFCEKNNLNFLMGSWWPNLEDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 SRTPGHQENNNFCSVNINIGPGDCEWFVVPEGYWGVLNDFCEKNNLNFLMGSWWPNLEDL
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KB3 YEANVPVYRFIQRPGDLVWINAGTVHWVQAIGWCNNIAWNVGPLTACQYKLAVERYEWNK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 YEANVPVYRFIQRPGDLVWINAGTVHWVQAIGWCNNIAWNVGPLTACQYKLAVERYEWNK
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KB3 LQSVKSIVPMVHLSWNMARNIKVSDPKLFEMIKYCLLRTLKQCQTLREALIAAGKEIIWH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 LQSVKSIVPMVHLSWNMARNIKVSDPKLFEMIKYCLLRTLKQCQTLREALIAAGKEIIWH
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KB3 GRTKEEPAHYCSICEVEVFDLLFVTNESNSRKTYIVHCQDCARKTSGNLENFVVLEQYKM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 GRTKEEPAHYCSICEVEVFDLLFVTNESNSRKTYIVHCQDCARKTSGNLENFVVLEQYKM
             1330      1340      1350      1360      1370      1380

             1390      1400 
pF1KB3 EDLMQVYDQFTLAPPLPSASS
       :::::::::::::::::::::
NP_066 EDLMQVYDQFTLAPPLPSASS
             1390      1400 

>>NP_001278345 (OMIM: 147920,300128,300867) lysine-speci  (1408 aa)
 initn: 9181 init1: 6537 opt: 9167  Z-score: 5779.1  bits: 1081.8 E(85289):    0
Smith-Waterman score: 9175; 96.9% identity (97.8% similar) in 1410 aa overlap (1-1401:1-1408)

               10        20        30        40        50        60
pF1KB3 MKSCGVSLATAAAAAAAFGDEEKKMAAGKASGESEEASPSLTAEEREALGGLDSRLFGFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKSCGVSLATAAAAAAAFGDEEKKMAAGKASGESEEASPSLTAEEREALGGLDSRLFGFV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 RFHEDGARTKALLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYPKALSAYQRYY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RFHEDGARTKALLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYPKALSAYQRYY
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 SLQSDYWKNAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDPSFCRAKEIHLRLGLMFKVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLQSDYWKNAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDPSFCRAKEIHLRLGLMFKVN
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 TDYESSLKHFQLALVDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLSAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TDYESSLKHFQLALVDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLSAQ
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 VKATVLQQLGWMHHTVDLLGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VKATVLQQLGWMHHTVDLLGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKV
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 QDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGT
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 LYESCNQPQDAIKCYLNATRSKSCSNTSALAARIKYLQAQLCNLPQGSLQNKTKLLPSIE
       :::::::::::::::::::::::::::::::::::::::  :.  . . .    :  .  
NP_001 LYESCNQPQDAIKCYLNATRSKSCSNTSALAARIKYLQA--CKPHHPNTEPVLGLSQTPI
              370       380       390         400       410        

                     430         440       450       460       470 
pF1KB3 EAWSLP---IPA----ELTS--RQGAMNTAQQNTSDNWSGGHAVSHPPVQQQAHSWCLTP
          :::   ::.    .:.:  ..   ..  .::::::::::::::::::::::::::::
NP_001 SQQSLPLHMIPSSQVDDLSSPAKRKRTSSPTKNTSDNWSGGHAVSHPPVQQQAHSWCLTP
      420       430       440       450       460       470        

             480       490       500       510       520       530 
pF1KB3 QKLQHLEQLRANRNNLNPAQKLMLEQLESQFVLMQQHQMRPTGVAQVRSTGIPNGPTADS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QKLQHLEQLRANRNNLNPAQKLMLEQLESQFVLMQQHQMRPTGVAQVRSTGIPNGPTADS
      480       490       500       510       520       530        

             540       550       560       570       580       590 
pF1KB3 SLPTNSVSGQQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAGHVPCSTSRTLGSTDTI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLPTNSVSGQQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAGHVPCSTSRTLGSTDTI
      540       550       560       570       580       590        

             600       610       620       630       640       650 
pF1KB3 LIGNNHITGSGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNSTQGLHKGQSSHS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LIGNNHITGSGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNSTQGLHKGQSSHS
      600       610       620       630       640       650        

             660       670       680       690       700       710 
pF1KB3 AGPNGERPLSSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALNHLSSHTATSGGQQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGPNGERPLSSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALNHLSSHTATSGGQQG
      660       670       680       690       700       710        

             720       730       740       750       760       770 
pF1KB3 ITLTKESKPSGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCSPSHGDSKSPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ITLTKESKPSGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCSPSHGDSKSPG
      720       730       740       750       760       770        

             780       790       800       810       820       830 
pF1KB3 LLSSDNPQLSALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSSAISTATPSPK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLSSDNPQLSALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSSAISTATPSPK
      780       790       800       810       820       830        

             840       850       860       870       880       890 
pF1KB3 STEQTTTNSVTSLNSPHSGLHTINGEGMEESQSPMKTDLLLVNHKPSPQIIPSMSVSIYP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STEQTTTNSVTSLNSPHSGLHTINGEGMEESQSPMKTDLLLVNHKPSPQIIPSMSVSIYP
      840       850       860       870       880       890        

             900       910       920       930       940       950 
pF1KB3 SSAEVLKACRNLGKNGLSNSSILLDKCPPPRPPSSPYPPLPKDKLNPPTPSIYLENKRDA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSAEVLKACRNLGKNGLSNSSILLDKCPPPRPPSSPYPPLPKDKLNPPTPSIYLENKRDA
      900       910       920       930       940       950        

             960       970       980       990      1000      1010 
pF1KB3 FFPPLHQFCTNPNNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FFPPLHQFCTNPNNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADEN
      960       970       980       990      1000      1010        

            1020      1030      1040      1050      1060      1070 
pF1KB3 WDPTGTKKIWHCESNRSHTTIAKYAQYQASSFQESLREENEKRSHHKDHSDSESTSSDNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WDPTGTKKIWHCESNRSHTTIAKYAQYQASSFQESLREENEKRSHHKDHSDSESTSSDNS
     1020      1030      1040      1050      1060      1070        

            1080      1090      1100      1110      1120      1130 
pF1KB3 GRRRKGPFKTIKFGTNIDLSDDKKWKLQLHELTKLPAFVRVVSAGNLLSHVGHTILGMNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GRRRKGPFKTIKFGTNIDLSDDKKWKLQLHELTKLPAFVRVVSAGNLLSHVGHTILGMNT
     1080      1090      1100      1110      1120      1130        

            1140      1150      1160      1170      1180      1190 
pF1KB3 VQLYMKVPGSRTPGHQENNNFCSVNINIGPGDCEWFVVPEGYWGVLNDFCEKNNLNFLMG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VQLYMKVPGSRTPGHQENNNFCSVNINIGPGDCEWFVVPEGYWGVLNDFCEKNNLNFLMG
     1140      1150      1160      1170      1180      1190        

            1200      1210      1220      1230      1240      1250 
pF1KB3 SWWPNLEDLYEANVPVYRFIQRPGDLVWINAGTVHWVQAIGWCNNIAWNVGPLTACQYKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SWWPNLEDLYEANVPVYRFIQRPGDLVWINAGTVHWVQAIGWCNNIAWNVGPLTACQYKL
     1200      1210      1220      1230      1240      1250        

            1260      1270      1280      1290      1300      1310 
pF1KB3 AVERYEWNKLQSVKSIVPMVHLSWNMARNIKVSDPKLFEMIKYCLLRTLKQCQTLREALI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVERYEWNKLQSVKSIVPMVHLSWNMARNIKVSDPKLFEMIKYCLLRTLKQCQTLREALI
     1260      1270      1280      1290      1300      1310        

            1320      1330      1340      1350      1360      1370 
pF1KB3 AAGKEIIWHGRTKEEPAHYCSICEVEVFDLLFVTNESNSRKTYIVHCQDCARKTSGNLEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAGKEIIWHGRTKEEPAHYCSICEVEVFDLLFVTNESNSRKTYIVHCQDCARKTSGNLEN
     1320      1330      1340      1350      1360      1370        

            1380      1390      1400 
pF1KB3 FVVLEQYKMEDLMQVYDQFTLAPPLPSASS
       ::::::::::::::::::::::::::::::
NP_001 FVVLEQYKMEDLMQVYDQFTLAPPLPSASS
     1380      1390      1400        

>>XP_011542266 (OMIM: 147920,300128,300867) PREDICTED: l  (1437 aa)
 initn: 8752 init1: 8752 opt: 8764  Z-score: 5525.3  bits: 1034.9 E(85289):    0
Smith-Waterman score: 9381; 97.5% identity (97.5% similar) in 1433 aa overlap (1-1397:1-1433)

               10        20        30        40        50        60
pF1KB3 MKSCGVSLATAAAAAAAFGDEEKKMAAGKASGESEEASPSLTAEEREALGGLDSRLFGFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKSCGVSLATAAAAAAAFGDEEKKMAAGKASGESEEASPSLTAEEREALGGLDSRLFGFV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 RFHEDGARTKALLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYPKALSAYQRYY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RFHEDGARTKALLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYPKALSAYQRYY
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 SLQSDYWKNAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDPSFCRAKEIHLRLGLMFKVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLQSDYWKNAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDPSFCRAKEIHLRLGLMFKVN
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 TDYESSLKHFQLALVDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLSAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TDYESSLKHFQLALVDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLSAQ
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 VKATVLQQLGWMHHTVDLLGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKATVLQQLGWMHHTVDLLGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKV
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 QDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGT
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 LYESCNQPQDAIKCYLNATRSKSCSNTSALAARIKYLQAQLCNLPQGSLQNKTKLLPSIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LYESCNQPQDAIKCYLNATRSKSCSNTSALAARIKYLQAQLCNLPQGSLQNKTKLLPSIE
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 EAWSLPIPAELTSRQGAMNTAQQNTSDNWSGGHAVSHPPVQQQAHSWCLTPQKLQHLEQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EAWSLPIPAELTSRQGAMNTAQQNTSDNWSGGHAVSHPPVQQQAHSWCLTPQKLQHLEQL
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB3 RANRNNLNPAQKLMLEQLESQFVLMQQHQMRPTGVAQVRSTGIPNGPTADSSLPTNSVSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RANRNNLNPAQKLMLEQLESQFVLMQQHQMRPTGVAQVRSTGIPNGPTADSSLPTNSVSG
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB3 QQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAGHVPCSTSRTLGSTDTILIGNNHITG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAGHVPCSTSRTLGSTDTILIGNNHITG
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB3 SGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNSTQGLHKGQSSHSAGPNGERPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNSTQGLHKGQSSHSAGPNGERPL
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB3 SSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALNHLSSHTATSGGQQGITLTKESKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALNHLSSHTATSGGQQGITLTKESKP
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB3 SGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCSPSHGDSKSPGLLSSDNPQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCSPSHGDSKSPGLLSSDNPQL
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB3 SALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSSAISTATPSPKSTEQTTTNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSSAISTATPSPKSTEQTTTNS
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB3 VTSLNSPHSGLHTINGEGMEESQSPMKTDLLLVNHKPSPQIIPSMSVSIYPSSAEVLKAC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTSLNSPHSGLHTINGEGMEESQSPMKTDLLLVNHKPSPQIIPSMSVSIYPSSAEVLKAC
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB3 RNLGKNGLSNSSILLDKCPPPRPPSSPYPPLPKDKLNPPTPSIYLENKRDAFFPPLHQFC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RNLGKNGLSNSSILLDKCPPPRPPSSPYPPLPKDKLNPPTPSIYLENKRDAFFPPLHQFC
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KB3 TNPNNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWDPTGTKKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TNPNNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWDPTGTKKI
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KB3 WHCESNRSHTTIAKYAQYQASSFQESLREENEKRSHHKDHSDSESTSSDNSGRRRKGPFK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WHCESNRSHTTIAKYAQYQASSFQESLREENEKRSHHKDHSDSESTSSDNSGRRRKGPFK
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KB3 TIKFGTNIDLSDDKKWKLQLHELTKLPAFVRVVSAGNLLSHVGHTILGMNTVQLYMKVPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TIKFGTNIDLSDDKKWKLQLHELTKLPAFVRVVSAGNLLSHVGHTILGMNTVQLYMKVPG
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KB3 SRTPGHQENNNFCSVNINIGPGDCEWFVVPEGYWGVLNDFCEKNNLNFLMGSWWPNLEDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRTPGHQENNNFCSVNINIGPGDCEWFVVPEGYWGVLNDFCEKNNLNFLMGSWWPNLEDL
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KB3 YEANVPVYRFIQRPGDLVWINAGTVHWVQAIGWCNNIAWNVGPLTACQYKLAVERYEWNK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YEANVPVYRFIQRPGDLVWINAGTVHWVQAIGWCNNIAWNVGPLTACQYKLAVERYEWNK
             1210      1220      1230      1240      1250      1260

             1270      1280      1290                              
pF1KB3 LQSVKSIVPMVHLSWNMARNIKVSDPKLFEMIK---------------------------
       :::::::::::::::::::::::::::::::::                           
XP_011 LQSVKSIVPMVHLSWNMARNIKVSDPKLFEMIKIFSLSPNFRAEKCLRDHLVQPLRSNGE
             1270      1280      1290      1300      1310      1320

                   1300      1310      1320      1330      1340    
pF1KB3 ---------YCLLRTLKQCQTLREALIAAGKEIIWHGRTKEEPAHYCSICEVEVFDLLFV
                :::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEPLRFTGEYCLLRTLKQCQTLREALIAAGKEIIWHGRTKEEPAHYCSICEVEVFDLLFV
             1330      1340      1350      1360      1370      1380

         1350      1360      1370      1380      1390      1400 
pF1KB3 TNESNSRKTYIVHCQDCARKTSGNLENFVVLEQYKMEDLMQVYDQFTLAPPLPSASS
       :::::::::::::::::::::::::::::::::::::::::::::::::::::    
XP_011 TNESNSRKTYIVHCQDCARKTSGNLENFVVLEQYKMEDLMQVYDQFTLAPPLPSASS
             1390      1400      1410      1420      1430       

>>XP_011542276 (OMIM: 147920,300128,300867) PREDICTED: l  (1293 aa)
 initn: 8752 init1: 8752 opt: 8752  Z-score: 5518.5  bits: 1033.5 E(85289):    0
Smith-Waterman score: 8752; 100.0% identity (100.0% similar) in 1293 aa overlap (1-1293:1-1293)

               10        20        30        40        50        60
pF1KB3 MKSCGVSLATAAAAAAAFGDEEKKMAAGKASGESEEASPSLTAEEREALGGLDSRLFGFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKSCGVSLATAAAAAAAFGDEEKKMAAGKASGESEEASPSLTAEEREALGGLDSRLFGFV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 RFHEDGARTKALLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYPKALSAYQRYY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RFHEDGARTKALLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYPKALSAYQRYY
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 SLQSDYWKNAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDPSFCRAKEIHLRLGLMFKVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLQSDYWKNAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDPSFCRAKEIHLRLGLMFKVN
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 TDYESSLKHFQLALVDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLSAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TDYESSLKHFQLALVDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLSAQ
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 VKATVLQQLGWMHHTVDLLGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKATVLQQLGWMHHTVDLLGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKV
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 QDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGT
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 LYESCNQPQDAIKCYLNATRSKSCSNTSALAARIKYLQAQLCNLPQGSLQNKTKLLPSIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LYESCNQPQDAIKCYLNATRSKSCSNTSALAARIKYLQAQLCNLPQGSLQNKTKLLPSIE
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 EAWSLPIPAELTSRQGAMNTAQQNTSDNWSGGHAVSHPPVQQQAHSWCLTPQKLQHLEQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EAWSLPIPAELTSRQGAMNTAQQNTSDNWSGGHAVSHPPVQQQAHSWCLTPQKLQHLEQL
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB3 RANRNNLNPAQKLMLEQLESQFVLMQQHQMRPTGVAQVRSTGIPNGPTADSSLPTNSVSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RANRNNLNPAQKLMLEQLESQFVLMQQHQMRPTGVAQVRSTGIPNGPTADSSLPTNSVSG
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB3 QQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAGHVPCSTSRTLGSTDTILIGNNHITG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAGHVPCSTSRTLGSTDTILIGNNHITG
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB3 SGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNSTQGLHKGQSSHSAGPNGERPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNSTQGLHKGQSSHSAGPNGERPL
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB3 SSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALNHLSSHTATSGGQQGITLTKESKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALNHLSSHTATSGGQQGITLTKESKP
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB3 SGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCSPSHGDSKSPGLLSSDNPQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCSPSHGDSKSPGLLSSDNPQL
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB3 SALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSSAISTATPSPKSTEQTTTNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSSAISTATPSPKSTEQTTTNS
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB3 VTSLNSPHSGLHTINGEGMEESQSPMKTDLLLVNHKPSPQIIPSMSVSIYPSSAEVLKAC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTSLNSPHSGLHTINGEGMEESQSPMKTDLLLVNHKPSPQIIPSMSVSIYPSSAEVLKAC
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB3 RNLGKNGLSNSSILLDKCPPPRPPSSPYPPLPKDKLNPPTPSIYLENKRDAFFPPLHQFC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RNLGKNGLSNSSILLDKCPPPRPPSSPYPPLPKDKLNPPTPSIYLENKRDAFFPPLHQFC
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KB3 TNPNNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWDPTGTKKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TNPNNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWDPTGTKKI
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KB3 WHCESNRSHTTIAKYAQYQASSFQESLREENEKRSHHKDHSDSESTSSDNSGRRRKGPFK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WHCESNRSHTTIAKYAQYQASSFQESLREENEKRSHHKDHSDSESTSSDNSGRRRKGPFK
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KB3 TIKFGTNIDLSDDKKWKLQLHELTKLPAFVRVVSAGNLLSHVGHTILGMNTVQLYMKVPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TIKFGTNIDLSDDKKWKLQLHELTKLPAFVRVVSAGNLLSHVGHTILGMNTVQLYMKVPG
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KB3 SRTPGHQENNNFCSVNINIGPGDCEWFVVPEGYWGVLNDFCEKNNLNFLMGSWWPNLEDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRTPGHQENNNFCSVNINIGPGDCEWFVVPEGYWGVLNDFCEKNNLNFLMGSWWPNLEDL
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KB3 YEANVPVYRFIQRPGDLVWINAGTVHWVQAIGWCNNIAWNVGPLTACQYKLAVERYEWNK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YEANVPVYRFIQRPGDLVWINAGTVHWVQAIGWCNNIAWNVGPLTACQYKLAVERYEWNK
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KB3 LQSVKSIVPMVHLSWNMARNIKVSDPKLFEMIKYCLLRTLKQCQTLREALIAAGKEIIWH
       :::::::::::::::::::::::::::::::::                           
XP_011 LQSVKSIVPMVHLSWNMARNIKVSDPKLFEMIK                           
             1270      1280      1290                              

             1330      1340      1350      1360      1370      1380
pF1KB3 GRTKEEPAHYCSICEVEVFDLLFVTNESNSRKTYIVHCQDCARKTSGNLENFVVLEQYKM

>>XP_011542269 (OMIM: 147920,300128,300867) PREDICTED: l  (1420 aa)
 initn: 8656 init1: 8656 opt: 8669  Z-score: 5465.6  bits: 1023.8 E(85289):    0
Smith-Waterman score: 9435; 98.7% identity (98.7% similar) in 1420 aa overlap (1-1401:1-1420)

               10        20        30        40        50        60
pF1KB3 MKSCGVSLATAAAAAAAFGDEEKKMAAGKASGESEEASPSLTAEEREALGGLDSRLFGFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKSCGVSLATAAAAAAAFGDEEKKMAAGKASGESEEASPSLTAEEREALGGLDSRLFGFV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 RFHEDGARTKALLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYPKALSAYQRYY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RFHEDGARTKALLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYPKALSAYQRYY
               70        80        90       100       110       120

                                 130       140       150       160 
pF1KB3 SLQSDYWK-------------------NAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDP
       ::::::::                   :::::::::::::::::::::::::::::::::
XP_011 SLQSDYWKMRNPWIQRAHCIPLDQYTTNAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDP
              130       140       150       160       170       180

             170       180       190       200       210       220 
pF1KB3 SFCRAKEIHLRLGLMFKVNTDYESSLKHFQLALVDCNPCTLSNAEIQFHIAHLYETQRKY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SFCRAKEIHLRLGLMFKVNTDYESSLKHFQLALVDCNPCTLSNAEIQFHIAHLYETQRKY
              190       200       210       220       230       240

             230       240       250       260       270       280 
pF1KB3 HSAKEAYEQLLQTENLSAQVKATVLQQLGWMHHTVDLLGDKATKESYAIQYLQKSLEADP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HSAKEAYEQLLQTENLSAQVKATVLQQLGWMHHTVDLLGDKATKESYAIQYLQKSLEADP
              250       260       270       280       290       300

             290       300       310       320       330       340 
pF1KB3 NSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAY
              310       320       330       340       350       360

             350       360       370       380       390       400 
pF1KB3 ICAVQLDHGHAAAWMDLGTLYESCNQPQDAIKCYLNATRSKSCSNTSALAARIKYLQAQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ICAVQLDHGHAAAWMDLGTLYESCNQPQDAIKCYLNATRSKSCSNTSALAARIKYLQAQL
              370       380       390       400       410       420

             410       420       430       440       450       460 
pF1KB3 CNLPQGSLQNKTKLLPSIEEAWSLPIPAELTSRQGAMNTAQQNTSDNWSGGHAVSHPPVQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CNLPQGSLQNKTKLLPSIEEAWSLPIPAELTSRQGAMNTAQQNTSDNWSGGHAVSHPPVQ
              430       440       450       460       470       480

             470       480       490       500       510       520 
pF1KB3 QQAHSWCLTPQKLQHLEQLRANRNNLNPAQKLMLEQLESQFVLMQQHQMRPTGVAQVRST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQAHSWCLTPQKLQHLEQLRANRNNLNPAQKLMLEQLESQFVLMQQHQMRPTGVAQVRST
              490       500       510       520       530       540

             530       540       550       560       570       580 
pF1KB3 GIPNGPTADSSLPTNSVSGQQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAGHVPCST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GIPNGPTADSSLPTNSVSGQQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAGHVPCST
              550       560       570       580       590       600

             590       600       610       620       630       640 
pF1KB3 SRTLGSTDTILIGNNHITGSGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNSTQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRTLGSTDTILIGNNHITGSGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNSTQ
              610       620       630       640       650       660

             650       660       670       680       690       700 
pF1KB3 GLHKGQSSHSAGPNGERPLSSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALNHLSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLHKGQSSHSAGPNGERPLSSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALNHLSS
              670       680       690       700       710       720

             710       720       730       740       750       760 
pF1KB3 HTATSGGQQGITLTKESKPSGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HTATSGGQQGITLTKESKPSGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCS
              730       740       750       760       770       780

             770       780       790       800       810       820 
pF1KB3 PSHGDSKSPGLLSSDNPQLSALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSHGDSKSPGLLSSDNPQLSALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSS
              790       800       810       820       830       840

             830       840       850       860       870       880 
pF1KB3 AISTATPSPKSTEQTTTNSVTSLNSPHSGLHTINGEGMEESQSPMKTDLLLVNHKPSPQI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AISTATPSPKSTEQTTTNSVTSLNSPHSGLHTINGEGMEESQSPMKTDLLLVNHKPSPQI
              850       860       870       880       890       900

             890       900       910       920       930       940 
pF1KB3 IPSMSVSIYPSSAEVLKACRNLGKNGLSNSSILLDKCPPPRPPSSPYPPLPKDKLNPPTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IPSMSVSIYPSSAEVLKACRNLGKNGLSNSSILLDKCPPPRPPSSPYPPLPKDKLNPPTP
              910       920       930       940       950       960

             950       960       970       980       990      1000 
pF1KB3 SIYLENKRDAFFPPLHQFCTNPNNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SIYLENKRDAFFPPLHQFCTNPNNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVR
              970       980       990      1000      1010      1020

            1010      1020      1030      1040      1050      1060 
pF1KB3 TQLLQPADENWDPTGTKKIWHCESNRSHTTIAKYAQYQASSFQESLREENEKRSHHKDHS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TQLLQPADENWDPTGTKKIWHCESNRSHTTIAKYAQYQASSFQESLREENEKRSHHKDHS
             1030      1040      1050      1060      1070      1080

            1070      1080      1090      1100      1110      1120 
pF1KB3 DSESTSSDNSGRRRKGPFKTIKFGTNIDLSDDKKWKLQLHELTKLPAFVRVVSAGNLLSH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSESTSSDNSGRRRKGPFKTIKFGTNIDLSDDKKWKLQLHELTKLPAFVRVVSAGNLLSH
             1090      1100      1110      1120      1130      1140

            1130      1140      1150      1160      1170      1180 
pF1KB3 VGHTILGMNTVQLYMKVPGSRTPGHQENNNFCSVNINIGPGDCEWFVVPEGYWGVLNDFC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VGHTILGMNTVQLYMKVPGSRTPGHQENNNFCSVNINIGPGDCEWFVVPEGYWGVLNDFC
             1150      1160      1170      1180      1190      1200

            1190      1200      1210      1220      1230      1240 
pF1KB3 EKNNLNFLMGSWWPNLEDLYEANVPVYRFIQRPGDLVWINAGTVHWVQAIGWCNNIAWNV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKNNLNFLMGSWWPNLEDLYEANVPVYRFIQRPGDLVWINAGTVHWVQAIGWCNNIAWNV
             1210      1220      1230      1240      1250      1260

            1250      1260      1270      1280      1290      1300 
pF1KB3 GPLTACQYKLAVERYEWNKLQSVKSIVPMVHLSWNMARNIKVSDPKLFEMIKYCLLRTLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPLTACQYKLAVERYEWNKLQSVKSIVPMVHLSWNMARNIKVSDPKLFEMIKYCLLRTLK
             1270      1280      1290      1300      1310      1320

            1310      1320      1330      1340      1350      1360 
pF1KB3 QCQTLREALIAAGKEIIWHGRTKEEPAHYCSICEVEVFDLLFVTNESNSRKTYIVHCQDC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QCQTLREALIAAGKEIIWHGRTKEEPAHYCSICEVEVFDLLFVTNESNSRKTYIVHCQDC
             1330      1340      1350      1360      1370      1380

            1370      1380      1390      1400 
pF1KB3 ARKTSGNLENFVVLEQYKMEDLMQVYDQFTLAPPLPSASS
       ::::::::::::::::::::::::::::::::::::::::
XP_011 ARKTSGNLENFVVLEQYKMEDLMQVYDQFTLAPPLPSASS
             1390      1400      1410      1420

>>XP_011542265 (OMIM: 147920,300128,300867) PREDICTED: l  (1444 aa)
 initn: 8450 init1: 5806 opt: 8448  Z-score: 5326.4  bits: 998.1 E(85289):    0
Smith-Waterman score: 9073; 94.5% identity (95.4% similar) in 1442 aa overlap (1-1397:1-1440)

               10        20        30        40        50        60
pF1KB3 MKSCGVSLATAAAAAAAFGDEEKKMAAGKASGESEEASPSLTAEEREALGGLDSRLFGFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKSCGVSLATAAAAAAAFGDEEKKMAAGKASGESEEASPSLTAEEREALGGLDSRLFGFV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 RFHEDGARTKALLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYPKALSAYQRYY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RFHEDGARTKALLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYPKALSAYQRYY
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 SLQSDYWKNAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDPSFCRAKEIHLRLGLMFKVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLQSDYWKNAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDPSFCRAKEIHLRLGLMFKVN
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 TDYESSLKHFQLALVDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLSAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TDYESSLKHFQLALVDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLSAQ
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 VKATVLQQLGWMHHTVDLLGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKATVLQQLGWMHHTVDLLGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKV
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 QDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGT
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 LYESCNQPQDAIKCYLNATRSKSCSNTSALAARIKYLQAQLCNLPQGSLQNKTKLLPSIE
       :::::::::::::::::::::::::::::::::::::::  :.  . . .    :  .  
XP_011 LYESCNQPQDAIKCYLNATRSKSCSNTSALAARIKYLQA--CKPHHPNTEPVLGLSQTPI
              370       380       390         400       410        

                     430         440       450       460       470 
pF1KB3 EAWSLP---IPA----ELTS--RQGAMNTAQQNTSDNWSGGHAVSHPPVQQQAHSWCLTP
          :::   ::.    .:.:  ..   ..  .::::::::::::::::::::::::::::
XP_011 SQQSLPLHMIPSSQVDDLSSPAKRKRTSSPTKNTSDNWSGGHAVSHPPVQQQAHSWCLTP
      420       430       440       450       460       470        

             480       490       500       510       520       530 
pF1KB3 QKLQHLEQLRANRNNLNPAQKLMLEQLESQFVLMQQHQMRPTGVAQVRSTGIPNGPTADS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QKLQHLEQLRANRNNLNPAQKLMLEQLESQFVLMQQHQMRPTGVAQVRSTGIPNGPTADS
      480       490       500       510       520       530        

             540       550       560       570       580       590 
pF1KB3 SLPTNSVSGQQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAGHVPCSTSRTLGSTDTI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLPTNSVSGQQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAGHVPCSTSRTLGSTDTI
      540       550       560       570       580       590        

             600       610       620       630       640       650 
pF1KB3 LIGNNHITGSGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNSTQGLHKGQSSHS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LIGNNHITGSGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNSTQGLHKGQSSHS
      600       610       620       630       640       650        

             660       670       680       690       700       710 
pF1KB3 AGPNGERPLSSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALNHLSSHTATSGGQQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGPNGERPLSSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALNHLSSHTATSGGQQG
      660       670       680       690       700       710        

             720       730       740       750       760       770 
pF1KB3 ITLTKESKPSGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCSPSHGDSKSPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ITLTKESKPSGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCSPSHGDSKSPG
      720       730       740       750       760       770        

             780       790       800       810       820       830 
pF1KB3 LLSSDNPQLSALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSSAISTATPSPK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLSSDNPQLSALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSSAISTATPSPK
      780       790       800       810       820       830        

             840       850       860       870       880       890 
pF1KB3 STEQTTTNSVTSLNSPHSGLHTINGEGMEESQSPMKTDLLLVNHKPSPQIIPSMSVSIYP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STEQTTTNSVTSLNSPHSGLHTINGEGMEESQSPMKTDLLLVNHKPSPQIIPSMSVSIYP
      840       850       860       870       880       890        

             900       910       920       930       940       950 
pF1KB3 SSAEVLKACRNLGKNGLSNSSILLDKCPPPRPPSSPYPPLPKDKLNPPTPSIYLENKRDA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSAEVLKACRNLGKNGLSNSSILLDKCPPPRPPSSPYPPLPKDKLNPPTPSIYLENKRDA
      900       910       920       930       940       950        

             960       970       980       990      1000      1010 
pF1KB3 FFPPLHQFCTNPNNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FFPPLHQFCTNPNNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADEN
      960       970       980       990      1000      1010        

            1020      1030      1040      1050      1060      1070 
pF1KB3 WDPTGTKKIWHCESNRSHTTIAKYAQYQASSFQESLREENEKRSHHKDHSDSESTSSDNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WDPTGTKKIWHCESNRSHTTIAKYAQYQASSFQESLREENEKRSHHKDHSDSESTSSDNS
     1020      1030      1040      1050      1060      1070        

            1080      1090      1100      1110      1120      1130 
pF1KB3 GRRRKGPFKTIKFGTNIDLSDDKKWKLQLHELTKLPAFVRVVSAGNLLSHVGHTILGMNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GRRRKGPFKTIKFGTNIDLSDDKKWKLQLHELTKLPAFVRVVSAGNLLSHVGHTILGMNT
     1080      1090      1100      1110      1120      1130        

            1140      1150      1160      1170      1180      1190 
pF1KB3 VQLYMKVPGSRTPGHQENNNFCSVNINIGPGDCEWFVVPEGYWGVLNDFCEKNNLNFLMG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VQLYMKVPGSRTPGHQENNNFCSVNINIGPGDCEWFVVPEGYWGVLNDFCEKNNLNFLMG
     1140      1150      1160      1170      1180      1190        

            1200      1210      1220      1230      1240      1250 
pF1KB3 SWWPNLEDLYEANVPVYRFIQRPGDLVWINAGTVHWVQAIGWCNNIAWNVGPLTACQYKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SWWPNLEDLYEANVPVYRFIQRPGDLVWINAGTVHWVQAIGWCNNIAWNVGPLTACQYKL
     1200      1210      1220      1230      1240      1250        

            1260      1270      1280      1290                     
pF1KB3 AVERYEWNKLQSVKSIVPMVHLSWNMARNIKVSDPKLFEMIK------------------
       ::::::::::::::::::::::::::::::::::::::::::                  
XP_011 AVERYEWNKLQSVKSIVPMVHLSWNMARNIKVSDPKLFEMIKIFSLSPNFRAEKCLRDHL
     1260      1270      1280      1290      1300      1310        

                            1300      1310      1320      1330     
pF1KB3 ------------------YCLLRTLKQCQTLREALIAAGKEIIWHGRTKEEPAHYCSICE
                         ::::::::::::::::::::::::::::::::::::::::::
XP_011 VQPLRSNGEPEPLRFTGEYCLLRTLKQCQTLREALIAAGKEIIWHGRTKEEPAHYCSICE
     1320      1330      1340      1350      1360      1370        

        1340      1350      1360      1370      1380      1390     
pF1KB3 VEVFDLLFVTNESNSRKTYIVHCQDCARKTSGNLENFVVLEQYKMEDLMQVYDQFTLAPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VEVFDLLFVTNESNSRKTYIVHCQDCARKTSGNLENFVVLEQYKMEDLMQVYDQFTLAPP
     1380      1390      1400      1410      1420      1430        

        1400 
pF1KB3 LPSASS
       ::    
XP_011 LPSASS
     1440    

>>XP_016885271 (OMIM: 147920,300128,300867) PREDICTED: l  (1427 aa)
 initn: 8354 init1: 6537 opt: 8347  Z-score: 5263.0  bits: 986.3 E(85289):    0
Smith-Waterman score: 9127; 95.6% identity (96.5% similar) in 1429 aa overlap (1-1401:1-1427)

               10        20        30        40        50        60
pF1KB3 MKSCGVSLATAAAAAAAFGDEEKKMAAGKASGESEEASPSLTAEEREALGGLDSRLFGFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKSCGVSLATAAAAAAAFGDEEKKMAAGKASGESEEASPSLTAEEREALGGLDSRLFGFV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 RFHEDGARTKALLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYPKALSAYQRYY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RFHEDGARTKALLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYPKALSAYQRYY
               70        80        90       100       110       120

                                 130       140       150       160 
pF1KB3 SLQSDYWK-------------------NAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDP
       ::::::::                   :::::::::::::::::::::::::::::::::
XP_016 SLQSDYWKMRNPWIQRAHCIPLDQYTTNAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDP
              130       140       150       160       170       180

             170       180       190       200       210       220 
pF1KB3 SFCRAKEIHLRLGLMFKVNTDYESSLKHFQLALVDCNPCTLSNAEIQFHIAHLYETQRKY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFCRAKEIHLRLGLMFKVNTDYESSLKHFQLALVDCNPCTLSNAEIQFHIAHLYETQRKY
              190       200       210       220       230       240

             230       240       250       260       270       280 
pF1KB3 HSAKEAYEQLLQTENLSAQVKATVLQQLGWMHHTVDLLGDKATKESYAIQYLQKSLEADP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HSAKEAYEQLLQTENLSAQVKATVLQQLGWMHHTVDLLGDKATKESYAIQYLQKSLEADP
              250       260       270       280       290       300

             290       300       310       320       330       340 
pF1KB3 NSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAY
              310       320       330       340       350       360

             350       360       370       380       390       400 
pF1KB3 ICAVQLDHGHAAAWMDLGTLYESCNQPQDAIKCYLNATRSKSCSNTSALAARIKYLQAQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::  
XP_016 ICAVQLDHGHAAAWMDLGTLYESCNQPQDAIKCYLNATRSKSCSNTSALAARIKYLQA--
              370       380       390       400       410          

             410       420              430         440       450  
pF1KB3 CNLPQGSLQNKTKLLPSIEEAWSLP---IPA----ELTS--RQGAMNTAQQNTSDNWSGG
       :.  . . .    :  .     :::   ::.    .:.:  ..   ..  .:::::::::
XP_016 CKPHHPNTEPVLGLSQTPISQQSLPLHMIPSSQVDDLSSPAKRKRTSSPTKNTSDNWSGG
      420       430       440       450       460       470        

            460       470       480       490       500       510  
pF1KB3 HAVSHPPVQQQAHSWCLTPQKLQHLEQLRANRNNLNPAQKLMLEQLESQFVLMQQHQMRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HAVSHPPVQQQAHSWCLTPQKLQHLEQLRANRNNLNPAQKLMLEQLESQFVLMQQHQMRP
      480       490       500       510       520       530        

            520       530       540       550       560       570  
pF1KB3 TGVAQVRSTGIPNGPTADSSLPTNSVSGQQPQLALTRVPSVSQPGVRPACPGQPLANGPF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TGVAQVRSTGIPNGPTADSSLPTNSVSGQQPQLALTRVPSVSQPGVRPACPGQPLANGPF
      540       550       560       570       580       590        

            580       590       600       610       620       630  
pF1KB3 SAGHVPCSTSRTLGSTDTILIGNNHITGSGSNGNVPYLQRNALTLPHNRTNLTSSAEEPW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SAGHVPCSTSRTLGSTDTILIGNNHITGSGSNGNVPYLQRNALTLPHNRTNLTSSAEEPW
      600       610       620       630       640       650        

            640       650       660       670       680       690  
pF1KB3 KNQLSNSTQGLHKGQSSHSAGPNGERPLSSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KNQLSNSTQGLHKGQSSHSAGPNGERPLSSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQ
      660       670       680       690       700       710        

            700       710       720       730       740       750  
pF1KB3 GAALNHLSSHTATSGGQQGITLTKESKPSGNILTVPETSRHTGETPNSTASVEGLPNHVH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GAALNHLSSHTATSGGQQGITLTKESKPSGNILTVPETSRHTGETPNSTASVEGLPNHVH
      720       730       740       750       760       770        

            760       770       780       790       800       810  
pF1KB3 QMTADAVCSPSHGDSKSPGLLSSDNPQLSALLMGKANNNVGTGTCDKVNNIHPAVHTKTD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QMTADAVCSPSHGDSKSPGLLSSDNPQLSALLMGKANNNVGTGTCDKVNNIHPAVHTKTD
      780       790       800       810       820       830        

            820       830       840       850       860       870  
pF1KB3 NSVASSPSSAISTATPSPKSTEQTTTNSVTSLNSPHSGLHTINGEGMEESQSPMKTDLLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSVASSPSSAISTATPSPKSTEQTTTNSVTSLNSPHSGLHTINGEGMEESQSPMKTDLLL
      840       850       860       870       880       890        

            880       890       900       910       920       930  
pF1KB3 VNHKPSPQIIPSMSVSIYPSSAEVLKACRNLGKNGLSNSSILLDKCPPPRPPSSPYPPLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNHKPSPQIIPSMSVSIYPSSAEVLKACRNLGKNGLSNSSILLDKCPPPRPPSSPYPPLP
      900       910       920       930       940       950        

            940       950       960       970       980       990  
pF1KB3 KDKLNPPTPSIYLENKRDAFFPPLHQFCTNPNNPVTVIRGLAGALKLDLGLFSTKTLVEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDKLNPPTPSIYLENKRDAFFPPLHQFCTNPNNPVTVIRGLAGALKLDLGLFSTKTLVEA
      960       970       980       990      1000      1010        

           1000      1010      1020      1030      1040      1050  
pF1KB3 NNEHMVEVRTQLLQPADENWDPTGTKKIWHCESNRSHTTIAKYAQYQASSFQESLREENE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NNEHMVEVRTQLLQPADENWDPTGTKKIWHCESNRSHTTIAKYAQYQASSFQESLREENE
     1020      1030      1040      1050      1060      1070        

           1060      1070      1080      1090      1100      1110  
pF1KB3 KRSHHKDHSDSESTSSDNSGRRRKGPFKTIKFGTNIDLSDDKKWKLQLHELTKLPAFVRV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRSHHKDHSDSESTSSDNSGRRRKGPFKTIKFGTNIDLSDDKKWKLQLHELTKLPAFVRV
     1080      1090      1100      1110      1120      1130        

           1120      1130      1140      1150      1160      1170  
pF1KB3 VSAGNLLSHVGHTILGMNTVQLYMKVPGSRTPGHQENNNFCSVNINIGPGDCEWFVVPEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSAGNLLSHVGHTILGMNTVQLYMKVPGSRTPGHQENNNFCSVNINIGPGDCEWFVVPEG
     1140      1150      1160      1170      1180      1190        

           1180      1190      1200      1210      1220      1230  
pF1KB3 YWGVLNDFCEKNNLNFLMGSWWPNLEDLYEANVPVYRFIQRPGDLVWINAGTVHWVQAIG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YWGVLNDFCEKNNLNFLMGSWWPNLEDLYEANVPVYRFIQRPGDLVWINAGTVHWVQAIG
     1200      1210      1220      1230      1240      1250        

           1240      1250      1260      1270      1280      1290  
pF1KB3 WCNNIAWNVGPLTACQYKLAVERYEWNKLQSVKSIVPMVHLSWNMARNIKVSDPKLFEMI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WCNNIAWNVGPLTACQYKLAVERYEWNKLQSVKSIVPMVHLSWNMARNIKVSDPKLFEMI
     1260      1270      1280      1290      1300      1310        

           1300      1310      1320      1330      1340      1350  
pF1KB3 KYCLLRTLKQCQTLREALIAAGKEIIWHGRTKEEPAHYCSICEVEVFDLLFVTNESNSRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KYCLLRTLKQCQTLREALIAAGKEIIWHGRTKEEPAHYCSICEVEVFDLLFVTNESNSRK
     1320      1330      1340      1350      1360      1370        

           1360      1370      1380      1390      1400 
pF1KB3 TYIVHCQDCARKTSGNLENFVVLEQYKMEDLMQVYDQFTLAPPLPSASS
       :::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TYIVHCQDCARKTSGNLENFVVLEQYKMEDLMQVYDQFTLAPPLPSASS
     1380      1390      1400      1410      1420       

>>XP_011529751 (OMIM: 400009) PREDICTED: histone demethy  (1530 aa)
 initn: 7885 init1: 3953 opt: 8143  Z-score: 5134.1  bits: 962.6 E(85289):    0
Smith-Waterman score: 8143; 86.5% identity (94.3% similar) in 1397 aa overlap (1-1397:1-1389)

               10        20        30        40        50        60
pF1KB3 MKSCGVSLATAAAAAAAFGDEEKKMAAGKASGESEEASPSLTAEEREALGGLDSRLFGFV
       ::::.:::.:::   .::::: :::: :::: :::: : :::.::::::::.::::::::
XP_011 MKSCAVSLTTAA---VAFGDEAKKMAEGKASRESEEESVSLTVEEREALGGMDSRLFGFV
               10           20        30        40        50       

               70        80        90       100       110       120
pF1KB3 RFHEDGARTKALLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYPKALSAYQRYY
       :.::::::::.:::::::::::::::::::::::::::::::::::::: ::::::::::
XP_011 RLHEDGARTKTLLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYSKALSAYQRYY
        60        70        80        90       100       110       

              130       140       150       160       170       180
pF1KB3 SLQSDYWKNAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDPSFCRAKEIHLRLGLMFKVN
       :::.:::::::::::::::::.::::.:::::::.:::::::::::::::::::::::::
XP_011 SLQADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVN
       120       130       140       150       160       170       

              190       200       210       220       230       240
pF1KB3 TDYESSLKHFQLALVDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLSAQ
       :::.::::::::::.:::::::::::::::::::::::::::::::::::::::::: ::
XP_011 TDYKSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQ
       180       190       200       210       220       230       

              250       260       270       280       290       300
pF1KB3 VKATVLQQLGWMHHTVDLLGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKV
       ::::::::::::::..::.:::::::::::::::::::::::::::::::::::::::::
XP_011 VKATVLQQLGWMHHNMDLVGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKV
       240       250       260       270       280       290       

              310       320       330       340       350       360
pF1KB3 QDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGT
       300       310       320       330       340       350       

              370       380       390       400       410       420
pF1KB3 LYESCNQPQDAIKCYLNATRSKSCSNTSALAARIKYLQAQLCNLPQGSLQNKTKLLPSIE
       ::::::::::::::::::.::: :::::.::::::.::::::::::.:::::::::::::
XP_011 LYESCNQPQDAIKCYLNAARSKRCSNTSTLAARIKFLQAQLCNLPQSSLQNKTKLLPSIE
       360       370       380       390       400       410       

              430       440       450       460       470       480
pF1KB3 EAWSLPIPAELTSRQGAMNTAQQNTSDNWSGGHAVSHPPVQQQAHSWCLTPQKLQHLEQL
       :::::::::::::::::::::::: ::::.::...:: :::: ..: :::::::::::::
XP_011 EAWSLPIPAELTSRQGAMNTAQQNGSDNWNGGQSLSHHPVQQ-VYSLCLTPQKLQHLEQL
       420       430       440       450        460       470      

              490       500       510       520       530       540
pF1KB3 RANRNNLNPAQKLMLEQLESQFVLMQQHQMRPTGVAQVRSTGIPNGPTADSSLPTNSVSG
       ::::.::::::: .:::::::::::::  ::   :::::.::: ::  .::::::::::.
XP_011 RANRDNLNPAQKHQLEQLESQFVLMQQ--MRHKEVAQVRTTGIHNGAITDSSLPTNSVSN
        480       490       500         510       520       530    

              550       560       570       580       590       600
pF1KB3 QQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAGHVPCSTSRTLGSTDTILIGNNHITG
       .::. ::::: :::::::::::  . :..: :::: .::.::. ::::::::.:.: :.:
XP_011 RQPHGALTRVSSVSQPGVRPACVEKLLSSGAFSAGCIPCGTSKILGSTDTILLGSNCIAG
          540       550       560       570       580       590    

              610       620       630       640       650       660
pF1KB3 SGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNSTQGLHKGQSSHSAGPNGERPL
       : :::::::::.:. :::::.:.:.::.::::..:::::.:::::.:::  .::: :.::
XP_011 SESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWRKQLSNSAQGLHKSQSSCLSGPNEEQPL
          600       610       620       630       640       650    

              670       680       690       700       710       720
pF1KB3 SSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALNHLSSHTATSGGQQGITLTKESKP
        ::: .:. ::...::.. : : ::::::: :: : .::: ::::::::::: .::::::
XP_011 FSTGSAQYHQATSTGIKKANEHLTLPSNSVPQGDADSHLSCHTATSGGQQGIMFTKESKP
          660       670       680       690       700       710    

              730       740       750       760       770       780
pF1KB3 SGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCSPSHGDSKSPGLLSSDNPQL
       : :   :::::::::.: :. :.:.:: :::::. :::: ::.:::  ::.:: .:::::
XP_011 SKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSPNHGD--SPNLLIADNPQL
          720       730       740       750       760         770  

              790       800       810       820       830       840
pF1KB3 SALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSSAISTATPSPKSTEQTTTNS
       ::::.::::.::::::::::::::::::::::.:::::::::::::::::::::: . ::
XP_011 SALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAISTATPSPKSTEQRSINS
            780       790       800       810       820       830  

              850       860       870       880       890       900
pF1KB3 VTSLNSPHSGLHTINGEGMEESQSPMKTDLLLVNHKPSPQIIPSMSVSIYPSSAEVLKAC
       :::::::::::::.::::. .:::  :.:: :..:. . ::.::::::: :::.::::::
XP_011 VTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASHRSTSQILPSMSVSICPSSTEVLKAC
            840       850       860       870       880       890  

              910       920       930       940       950       960
pF1KB3 RNLGKNGLSNSSILLDKCPPPRPPSSPYPPLPKDKLNPPTPSIYLENKRDAFFPPLHQFC
       :: :::::::: ::::::::::::.:::::::::::::::::::::::::::::::::::
XP_011 RNPGKNGLSNSCILLDKCPPPRPPTSPYPPLPKDKLNPPTPSIYLENKRDAFFPPLHQFC
            900       910       920       930       940       950  

              970       980       990      1000      1010      1020
pF1KB3 TNPNNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWDPTGTKKI
       :::.::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TNPKNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWDPTGTKKI
            960       970       980       990      1000      1010  

             1030      1040      1050      1060      1070      1080
pF1KB3 WHCESNRSHTTIAKYAQYQASSFQESLREENEKRSHHKDHSDSESTSSDNSGRRRKGPFK
       :.::::::::::::::::::::::::::::::::..::::::.:::::.:::::::::::
XP_011 WRCESNRSHTTIAKYAQYQASSFQESLREENEKRTQHKDHSDNESTSSENSGRRRKGPFK
           1020      1030      1040      1050      1060      1070  

             1090      1100      1110      1120      1130      1140
pF1KB3 TIKFGTNIDLSDDKKWKLQLHELTKLPAFVRVVSAGNLLSHVGHTILGMNTVQLYMKVPG
       ::::::::::::.::::::::::::::::.:::::::::.::::::::::::::::::::
XP_011 TIKFGTNIDLSDNKKWKLQLHELTKLPAFARVVSAGNLLTHVGHTILGMNTVQLYMKVPG
           1080      1090      1100      1110      1120      1130  

             1150      1160      1170      1180      1190      1200
pF1KB3 SRTPGHQENNNFCSVNINIGPGDCEWFVVPEGYWGVLNDFCEKNNLNFLMGSWWPNLEDL
       ::::::::::::::::::::::::::::::: ::::::::::::::::::.:::::::::
XP_011 SRTPGHQENNNFCSVNINIGPGDCEWFVVPEDYWGVLNDFCEKNNLNFLMSSWWPNLEDL
           1140      1150      1160      1170      1180      1190  

             1210      1220      1230      1240      1250      1260
pF1KB3 YEANVPVYRFIQRPGDLVWINAGTVHWVQAIGWCNNIAWNVGPLTACQYKLAVERYEWNK
       ::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::
XP_011 YEANVPVYRFIQRPGDLVWINAGTVHWVQAVGWCNNIAWNVGPLTACQYKLAVERYEWNK
           1200      1210      1220      1230      1240      1250  

             1270      1280      1290      1300      1310      1320
pF1KB3 LQSVKSIVPMVHLSWNMARNIKVSDPKLFEMIKYCLLRTLKQCQTLREALIAAGKEIIWH
       :.:::: ::::::::::::::::::::::::::::::. ::: :::::::.:::::.:::
XP_011 LKSVKSPVPMVHLSWNMARNIKVSDPKLFEMIKYCLLKILKQYQTLREALVAAGKEVIWH
           1260      1270      1280      1290      1300      1310  

             1330      1340      1350      1360      1370      1380
pF1KB3 GRTKEEPAHYCSICEVEVFDLLFVTNESNSRKTYIVHCQDCARKTSGNLENFVVLEQYKM
       :::..::::::::::::::.:::::::::..:::::::.::::::: .::::::::::::
XP_011 GRTNDEPAHYCSICEVEVFNLLFVTNESNTQKTYIVHCHDCARKTSKSLENFVVLEQYKM
           1320      1330      1340      1350      1360      1370  

             1390      1400                                        
pF1KB3 EDLMQVYDQFTLAPPLPSASS                                       
       :::.::::::::: : :                                           
XP_011 EDLIQVYDQFTLASPWPPMDQSAFTSSLLRPIKALGSGRAEQTSGDQLQKGATHSRASSL
           1380      1390      1400      1410      1420      1430  

>>NP_001245181 (OMIM: 400009) histone demethylase UTY is  (1392 aa)
 initn: 6742 init1: 3937 opt: 8136  Z-score: 5130.3  bits: 961.8 E(85289):    0
Smith-Waterman score: 8136; 86.4% identity (94.3% similar) in 1400 aa overlap (1-1400:1-1392)

               10        20        30        40        50        60
pF1KB3 MKSCGVSLATAAAAAAAFGDEEKKMAAGKASGESEEASPSLTAEEREALGGLDSRLFGFV
       ::::.:::.:::   .::::: :::: :::: :::: : :::.::::::::.::::::::
NP_001 MKSCAVSLTTAA---VAFGDEAKKMAEGKASRESEEESVSLTVEEREALGGMDSRLFGFV
               10           20        30        40        50       

               70        80        90       100       110       120
pF1KB3 RFHEDGARTKALLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYPKALSAYQRYY
       :.::::::::.:::::::::::::::::::::::::::::::::::::: ::::::::::
NP_001 RLHEDGARTKTLLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYSKALSAYQRYY
        60        70        80        90       100       110       

              130       140       150       160       170       180
pF1KB3 SLQSDYWKNAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDPSFCRAKEIHLRLGLMFKVN
       :::.:::::::::::::::::.::::.:::::::.:::::::::::::::::::::::::
NP_001 SLQADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVN
       120       130       140       150       160       170       

              190       200       210       220       230       240
pF1KB3 TDYESSLKHFQLALVDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLSAQ
       :::.::::::::::.:::::::::::::::::::::::::::::::::::::::::: ::
NP_001 TDYKSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQ
       180       190       200       210       220       230       

              250       260       270       280       290       300
pF1KB3 VKATVLQQLGWMHHTVDLLGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKV
       ::::::::::::::..::.:::::::::::::::::::::::::::::::::::::::::
NP_001 VKATVLQQLGWMHHNMDLVGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKV
       240       250       260       270       280       290       

              310       320       330       340       350       360
pF1KB3 QDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGT
       300       310       320       330       340       350       

              370       380       390       400       410       420
pF1KB3 LYESCNQPQDAIKCYLNATRSKSCSNTSALAARIKYLQAQLCNLPQGSLQNKTKLLPSIE
       ::::::::::::::::::.::: :::::.::::::.::::::::::.:::::::::::::
NP_001 LYESCNQPQDAIKCYLNAARSKRCSNTSTLAARIKFLQAQLCNLPQSSLQNKTKLLPSIE
       360       370       380       390       400       410       

              430       440       450       460       470       480
pF1KB3 EAWSLPIPAELTSRQGAMNTAQQNTSDNWSGGHAVSHPPVQQQAHSWCLTPQKLQHLEQL
       :::::::::::::::::::::::: ::::.::...:: :::: ..: :::::::::::::
NP_001 EAWSLPIPAELTSRQGAMNTAQQNGSDNWNGGQSLSHHPVQQ-VYSLCLTPQKLQHLEQL
       420       430       440       450        460       470      

              490       500       510       520       530       540
pF1KB3 RANRNNLNPAQKLMLEQLESQFVLMQQHQMRPTGVAQVRSTGIPNGPTADSSLPTNSVSG
       ::::.::::::: .::::::::::::  :::   :::::.::: ::  .::::::::::.
NP_001 RANRDNLNPAQKHQLEQLESQFVLMQ--QMRHKEVAQVRTTGIHNGAITDSSLPTNSVSN
        480       490       500         510       520       530    

              550       560       570       580       590       600
pF1KB3 QQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAGHVPCSTSRTLGSTDTILIGNNHITG
       .::. ::::: :::::::::::  . :..: :::: .::.::. ::::::::.:.: :.:
NP_001 RQPHGALTRVSSVSQPGVRPACVEKLLSSGAFSAGCIPCGTSKILGSTDTILLGSNCIAG
          540       550       560       570       580       590    

              610       620       630       640       650       660
pF1KB3 SGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNSTQGLHKGQSSHSAGPNGERPL
       : :::::::::.:. :::::.:.:.::.::::..:::::.:::::.:::  .::: :.::
NP_001 SESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWRKQLSNSAQGLHKSQSSCLSGPNEEQPL
          600       610       620       630       640       650    

              670       680       690       700       710       720
pF1KB3 SSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALNHLSSHTATSGGQQGITLTKESKP
        ::: .:. ::...::.. : : ::::::: :: : .::: ::::::::::: .::::::
NP_001 FSTGSAQYHQATSTGIKKANEHLTLPSNSVPQGDADSHLSCHTATSGGQQGIMFTKESKP
          660       670       680       690       700       710    

              730       740       750       760       770       780
pF1KB3 SGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCSPSHGDSKSPGLLSSDNPQL
       : :   :::::::::.: :. :.:.:: :::::. :::: ::.::::  :.:: .:::::
NP_001 SKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSPNHGDS--PNLLIADNPQL
          720       730       740       750       760         770  

              790       800       810       820       830       840
pF1KB3 SALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSSAISTATPSPKSTEQTTTNS
       ::::.::::.::::::::::::::::::::::.:::::::::::::::::::::: . ::
NP_001 SALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAISTATPSPKSTEQRSINS
            780       790       800       810       820       830  

              850       860       870       880       890       900
pF1KB3 VTSLNSPHSGLHTINGEGMEESQSPMKTDLLLVNHKPSPQIIPSMSVSIYPSSAEVLKAC
       :::::::::::::.::::. .:::  :.:: :..:. . ::.::::::: :::.::::::
NP_001 VTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASHRSTSQILPSMSVSICPSSTEVLKAC
            840       850       860       870       880       890  

              910       920       930       940       950       960
pF1KB3 RNLGKNGLSNSSILLDKCPPPRPPSSPYPPLPKDKLNPPTPSIYLENKRDAFFPPLHQFC
       :: :::::::: ::::::::::::.:::::::::::::::::::::::::::::::::::
NP_001 RNPGKNGLSNSCILLDKCPPPRPPTSPYPPLPKDKLNPPTPSIYLENKRDAFFPPLHQFC
            900       910       920       930       940       950  

              970       980       990      1000      1010      1020
pF1KB3 TNPNNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWDPTGTKKI
       :::.::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TNPKNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWDPTGTKKI
            960       970       980       990      1000      1010  

             1030      1040      1050      1060      1070      1080
pF1KB3 WHCESNRSHTTIAKYAQYQASSFQESLREENEKRSHHKDHSDSESTSSDNSGRRRKGPFK
       :.::::::::::::::::::::::::::::::::..::::::.:::::.:::::::::::
NP_001 WRCESNRSHTTIAKYAQYQASSFQESLREENEKRTQHKDHSDNESTSSENSGRRRKGPFK
           1020      1030      1040      1050      1060      1070  

             1090      1100      1110      1120      1130      1140
pF1KB3 TIKFGTNIDLSDDKKWKLQLHELTKLPAFVRVVSAGNLLSHVGHTILGMNTVQLYMKVPG
       ::::::::::::.::::::::::::::::.:::::::::.::::::::::::::::::::
NP_001 TIKFGTNIDLSDNKKWKLQLHELTKLPAFARVVSAGNLLTHVGHTILGMNTVQLYMKVPG
           1080      1090      1100      1110      1120      1130  

             1150      1160      1170      1180      1190      1200
pF1KB3 SRTPGHQENNNFCSVNINIGPGDCEWFVVPEGYWGVLNDFCEKNNLNFLMGSWWPNLEDL
       ::::::::::::::::::::::::::::::: ::::::::::::::::::.:::::::::
NP_001 SRTPGHQENNNFCSVNINIGPGDCEWFVVPEDYWGVLNDFCEKNNLNFLMSSWWPNLEDL
           1140      1150      1160      1170      1180      1190  

             1210      1220      1230      1240      1250      1260
pF1KB3 YEANVPVYRFIQRPGDLVWINAGTVHWVQAIGWCNNIAWNVGPLTACQYKLAVERYEWNK
       ::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::
NP_001 YEANVPVYRFIQRPGDLVWINAGTVHWVQAVGWCNNIAWNVGPLTACQYKLAVERYEWNK
           1200      1210      1220      1230      1240      1250  

             1270      1280      1290      1300      1310      1320
pF1KB3 LQSVKSIVPMVHLSWNMARNIKVSDPKLFEMIKYCLLRTLKQCQTLREALIAAGKEIIWH
       :.:::: ::::::::::::::::::::::::::::::. ::: :::::::.:::::.:::
NP_001 LKSVKSPVPMVHLSWNMARNIKVSDPKLFEMIKYCLLKILKQYQTLREALVAAGKEVIWH
           1260      1270      1280      1290      1300      1310  

             1330      1340      1350      1360      1370      1380
pF1KB3 GRTKEEPAHYCSICEVEVFDLLFVTNESNSRKTYIVHCQDCARKTSGNLENFVVLEQYKM
       :::..::::::::::::::.:::::::::..:::::::.::::::: .::::::::::::
NP_001 GRTNDEPAHYCSICEVEVFNLLFVTNESNTQKTYIVHCHDCARKTSKSLENFVVLEQYKM
           1320      1330      1340      1350      1360      1370  

             1390      1400 
pF1KB3 EDLMQVYDQFTLAPPLPSASS
       :::.:::::::::  : :.: 
NP_001 EDLIQVYDQFTLALSLSSSS 
           1380      1390   

>>XP_016885556 (OMIM: 400009) PREDICTED: histone demethy  (1387 aa)
 initn: 6737 init1: 3932 opt: 8121  Z-score: 5120.9  bits: 960.0 E(85289):    0
Smith-Waterman score: 8121; 86.6% identity (94.5% similar) in 1392 aa overlap (1-1392:1-1384)

               10        20        30        40        50        60
pF1KB3 MKSCGVSLATAAAAAAAFGDEEKKMAAGKASGESEEASPSLTAEEREALGGLDSRLFGFV
       ::::.:::.:::   .::::: :::: :::: :::: : :::.::::::::.::::::::
XP_016 MKSCAVSLTTAA---VAFGDEAKKMAEGKASRESEEESVSLTVEEREALGGMDSRLFGFV
               10           20        30        40        50       

               70        80        90       100       110       120
pF1KB3 RFHEDGARTKALLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYPKALSAYQRYY
       :.::::::::.:::::::::::::::::::::::::::::::::::::: ::::::::::
XP_016 RLHEDGARTKTLLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYSKALSAYQRYY
        60        70        80        90       100       110       

              130       140       150       160       170       180
pF1KB3 SLQSDYWKNAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDPSFCRAKEIHLRLGLMFKVN
       :::.:::::::::::::::::.::::.:::::::.:::::::::::::::::::::::::
XP_016 SLQADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVN
       120       130       140       150       160       170       

              190       200       210       220       230       240
pF1KB3 TDYESSLKHFQLALVDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLSAQ
       :::.::::::::::.:::::::::::::::::::::::::::::::::::::::::: ::
XP_016 TDYKSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQ
       180       190       200       210       220       230       

              250       260       270       280       290       300
pF1KB3 VKATVLQQLGWMHHTVDLLGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKV
       ::::::::::::::..::.:::::::::::::::::::::::::::::::::::::::::
XP_016 VKATVLQQLGWMHHNMDLVGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKV
       240       250       260       270       280       290       

              310       320       330       340       350       360
pF1KB3 QDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGT
       300       310       320       330       340       350       

              370       380       390       400       410       420
pF1KB3 LYESCNQPQDAIKCYLNATRSKSCSNTSALAARIKYLQAQLCNLPQGSLQNKTKLLPSIE
       ::::::::::::::::::.::: :::::.::::::.::::::::::.:::::::::::::
XP_016 LYESCNQPQDAIKCYLNAARSKRCSNTSTLAARIKFLQAQLCNLPQSSLQNKTKLLPSIE
       360       370       380       390       400       410       

              430       440       450       460       470       480
pF1KB3 EAWSLPIPAELTSRQGAMNTAQQNTSDNWSGGHAVSHPPVQQQAHSWCLTPQKLQHLEQL
       :::::::::::::::::::::::: ::::.::...:: :::: ..: :::::::::::::
XP_016 EAWSLPIPAELTSRQGAMNTAQQNGSDNWNGGQSLSHHPVQQ-VYSLCLTPQKLQHLEQL
       420       430       440       450        460       470      

              490       500       510       520       530       540
pF1KB3 RANRNNLNPAQKLMLEQLESQFVLMQQHQMRPTGVAQVRSTGIPNGPTADSSLPTNSVSG
       ::::.::::::: .::::::::::::  :::   :::::.::: ::  .::::::::::.
XP_016 RANRDNLNPAQKHQLEQLESQFVLMQ--QMRHKEVAQVRTTGIHNGAITDSSLPTNSVSN
        480       490       500         510       520       530    

              550       560       570       580       590       600
pF1KB3 QQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAGHVPCSTSRTLGSTDTILIGNNHITG
       .::. ::::: :::::::::::  . :..: :::: .::.::. ::::::::.:.: :.:
XP_016 RQPHGALTRVSSVSQPGVRPACVEKLLSSGAFSAGCIPCGTSKILGSTDTILLGSNCIAG
          540       550       560       570       580       590    

              610       620       630       640       650       660
pF1KB3 SGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNSTQGLHKGQSSHSAGPNGERPL
       : :::::::::.:. :::::.:.:.::.::::..:::::.:::::.:::  .::: :.::
XP_016 SESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWRKQLSNSAQGLHKSQSSCLSGPNEEQPL
          600       610       620       630       640       650    

              670       680       690       700       710       720
pF1KB3 SSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALNHLSSHTATSGGQQGITLTKESKP
        ::: .:. ::...::.. : : ::::::: :: : .::: ::::::::::: .::::::
XP_016 FSTGSAQYHQATSTGIKKANEHLTLPSNSVPQGDADSHLSCHTATSGGQQGIMFTKESKP
          660       670       680       690       700       710    

              730       740       750       760       770       780
pF1KB3 SGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCSPSHGDSKSPGLLSSDNPQL
       : :   :::::::::.: :. :.:.:: :::::. :::: ::.::::  :.:: .:::::
XP_016 SKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSPNHGDS--PNLLIADNPQL
          720       730       740       750       760         770  

              790       800       810       820       830       840
pF1KB3 SALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSSAISTATPSPKSTEQTTTNS
       ::::.::::.::::::::::::::::::::::.:::::::::::::::::::::: . ::
XP_016 SALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAISTATPSPKSTEQRSINS
            780       790       800       810       820       830  

              850       860       870       880       890       900
pF1KB3 VTSLNSPHSGLHTINGEGMEESQSPMKTDLLLVNHKPSPQIIPSMSVSIYPSSAEVLKAC
       :::::::::::::.::::. .:::  :.:: :..:. . ::.::::::: :::.::::::
XP_016 VTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASHRSTSQILPSMSVSICPSSTEVLKAC
            840       850       860       870       880       890  

              910       920       930       940       950       960
pF1KB3 RNLGKNGLSNSSILLDKCPPPRPPSSPYPPLPKDKLNPPTPSIYLENKRDAFFPPLHQFC
       :: :::::::: ::::::::::::.:::::::::::::::::::::::::::::::::::
XP_016 RNPGKNGLSNSCILLDKCPPPRPPTSPYPPLPKDKLNPPTPSIYLENKRDAFFPPLHQFC
            900       910       920       930       940       950  

              970       980       990      1000      1010      1020
pF1KB3 TNPNNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWDPTGTKKI
       :::.::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TNPKNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWDPTGTKKI
            960       970       980       990      1000      1010  

             1030      1040      1050      1060      1070      1080
pF1KB3 WHCESNRSHTTIAKYAQYQASSFQESLREENEKRSHHKDHSDSESTSSDNSGRRRKGPFK
       :.::::::::::::::::::::::::::::::::..::::::.:::::.:::::::::::
XP_016 WRCESNRSHTTIAKYAQYQASSFQESLREENEKRTQHKDHSDNESTSSENSGRRRKGPFK
           1020      1030      1040      1050      1060      1070  

             1090      1100      1110      1120      1130      1140
pF1KB3 TIKFGTNIDLSDDKKWKLQLHELTKLPAFVRVVSAGNLLSHVGHTILGMNTVQLYMKVPG
       ::::::::::::.::::::::::::::::.:::::::::.::::::::::::::::::::
XP_016 TIKFGTNIDLSDNKKWKLQLHELTKLPAFARVVSAGNLLTHVGHTILGMNTVQLYMKVPG
           1080      1090      1100      1110      1120      1130  

             1150      1160      1170      1180      1190      1200
pF1KB3 SRTPGHQENNNFCSVNINIGPGDCEWFVVPEGYWGVLNDFCEKNNLNFLMGSWWPNLEDL
       ::::::::::::::::::::::::::::::: ::::::::::::::::::.:::::::::
XP_016 SRTPGHQENNNFCSVNINIGPGDCEWFVVPEDYWGVLNDFCEKNNLNFLMSSWWPNLEDL
           1140      1150      1160      1170      1180      1190  

             1210      1220      1230      1240      1250      1260
pF1KB3 YEANVPVYRFIQRPGDLVWINAGTVHWVQAIGWCNNIAWNVGPLTACQYKLAVERYEWNK
       ::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::
XP_016 YEANVPVYRFIQRPGDLVWINAGTVHWVQAVGWCNNIAWNVGPLTACQYKLAVERYEWNK
           1200      1210      1220      1230      1240      1250  

             1270      1280      1290      1300      1310      1320
pF1KB3 LQSVKSIVPMVHLSWNMARNIKVSDPKLFEMIKYCLLRTLKQCQTLREALIAAGKEIIWH
       :.:::: ::::::::::::::::::::::::::::::. ::: :::::::.:::::.:::
XP_016 LKSVKSPVPMVHLSWNMARNIKVSDPKLFEMIKYCLLKILKQYQTLREALVAAGKEVIWH
           1260      1270      1280      1290      1300      1310  

             1330      1340      1350      1360      1370      1380
pF1KB3 GRTKEEPAHYCSICEVEVFDLLFVTNESNSRKTYIVHCQDCARKTSGNLENFVVLEQYKM
       :::..::::::::::::::.:::::::::..:::::::.::::::: .::::::::::::
XP_016 GRTNDEPAHYCSICEVEVFNLLFVTNESNTQKTYIVHCHDCARKTSKSLENFVVLEQYKM
           1320      1330      1340      1350      1360      1370  

             1390      1400 
pF1KB3 EDLMQVYDQFTLAPPLPSASS
       :::.::::::::         
XP_016 EDLIQVYDQFTLVSH      
           1380             




1401 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Wed Nov  2 22:44:16 2016 done: Wed Nov  2 22:44:18 2016
 Total Scan time: 14.100 Total Display time:  0.670

Function used was FASTA [36.3.4 Apr, 2011]
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