Result of FASTA (omim) for pF1KA2034
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KA2034, 2036 aa
  1>>>pF1KA2034 2036 - 2036 aa - 2036 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 17.5265+/-0.00054; mu= -36.2920+/- 0.033
 mean_var=754.7141+/-156.802, 0's: 0 Z-trim(119.6): 643  B-trim: 0 in 0/56
 Lambda= 0.046686
 statistics sampled from 33145 (33896) to 33145 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.687), E-opt: 0.2 (0.397), width:  16
 Scan time: 22.040

The best scores are:                                      opt bits E(85289)
NP_001139281 (OMIM: 600652,608568,614369) myosin-1 (2036) 13009 893.8       0
NP_079005 (OMIM: 600652,608568,614369) myosin-14 i (1995) 8442 586.2 1.2e-165
XP_006723449 (OMIM: 600652,608568,614369) PREDICTE (2003) 8442 586.2 1.2e-165
XP_011525625 (OMIM: 600652,608568,614369) PREDICTE (2003) 8442 586.2 1.2e-165
NP_001070654 (OMIM: 600652,608568,614369) myosin-1 (2003) 8442 586.2 1.2e-165
XP_011525623 (OMIM: 600652,608568,614369) PREDICTE (2035) 8442 586.2 1.2e-165
XP_011525622 (OMIM: 600652,608568,614369) PREDICTE (2043) 8442 586.2 1.2e-165
NP_001242941 (OMIM: 160776) myosin-10 isoform 1 [H (2007) 6225 436.9 1.1e-120
XP_011522177 (OMIM: 160776) PREDICTED: myosin-10 i (2037) 6225 436.9 1.1e-120
NP_005955 (OMIM: 160776) myosin-10 isoform 2 [Homo (1976) 5391 380.7 8.6e-104
XP_016880171 (OMIM: 160776) PREDICTED: myosin-10 i (1976) 5391 380.7 8.6e-104
XP_016880170 (OMIM: 160776) PREDICTED: myosin-10 i (1976) 5391 380.7 8.6e-104
NP_001243024 (OMIM: 160776) myosin-10 isoform 3 [H (1985) 5391 380.7 8.7e-104
XP_016880169 (OMIM: 160776) PREDICTED: myosin-10 i (1985) 5391 380.7 8.7e-104
XP_016880166 (OMIM: 160776) PREDICTED: myosin-10 i (1986) 5391 380.7 8.7e-104
XP_016880167 (OMIM: 160776) PREDICTED: myosin-10 i (1986) 5391 380.7 8.7e-104
XP_016880168 (OMIM: 160776) PREDICTED: myosin-10 i (1986) 5391 380.7 8.7e-104
XP_011522182 (OMIM: 160776) PREDICTED: myosin-10 i (2006) 5391 380.7 8.7e-104
XP_011522181 (OMIM: 160776) PREDICTED: myosin-10 i (2015) 5391 380.7 8.8e-104
XP_011522180 (OMIM: 160776) PREDICTED: myosin-10 i (2016) 5391 380.7 8.8e-104
XP_016884295 (OMIM: 153640,153650,155100,160775,60 (1960) 5245 370.9 7.8e-101
XP_016884294 (OMIM: 153640,153650,155100,160775,60 (1960) 5245 370.9 7.8e-101
XP_016884292 (OMIM: 153640,153650,155100,160775,60 (1960) 5245 370.9 7.8e-101
XP_011528499 (OMIM: 153640,153650,155100,160775,60 (1960) 5245 370.9 7.8e-101
NP_002464 (OMIM: 153640,153650,155100,160775,60020 (1960) 5245 370.9 7.8e-101
XP_016884293 (OMIM: 153640,153650,155100,160775,60 (1960) 5245 370.9 7.8e-101
NP_002465 (OMIM: 132900,160745) myosin-11 isoform  (1972) 5079 359.7 1.8e-97
NP_001035203 (OMIM: 132900,160745) myosin-11 isofo (1979) 5079 359.7 1.8e-97
NP_074035 (OMIM: 132900,160745) myosin-11 isoform  (1938) 5062 358.5   4e-97
XP_016878739 (OMIM: 132900,160745) PREDICTED: myos (1945) 5062 358.5   4e-97
NP_001035202 (OMIM: 132900,160745) myosin-11 isofo (1945) 5062 358.5   4e-97
XP_011520804 (OMIM: 132900,160745) PREDICTED: myos (1929) 5056 358.1 5.2e-97
XP_016880164 (OMIM: 160730) PREDICTED: myosin-1 is (1939) 2529 187.9 9.1e-46
NP_005954 (OMIM: 160730) myosin-1 [Homo sapiens]   (1939) 2529 187.9 9.1e-46
NP_001093582 (OMIM: 160740,605637) myosin-2 [Homo  (1941) 2525 187.7 1.1e-45
NP_060004 (OMIM: 160740,605637) myosin-2 [Homo sap (1941) 2525 187.7 1.1e-45
XP_011522173 (OMIM: 160720,178110,193700,601680) P (1940) 2518 187.2 1.5e-45
NP_002461 (OMIM: 160720,178110,193700,601680) myos (1940) 2518 187.2 1.5e-45
XP_011522172 (OMIM: 160720,178110,193700,601680) P (1940) 2518 187.2 1.5e-45
NP_002463 (OMIM: 158300,160741,608837) myosin-8 [H (1937) 2511 186.7 2.1e-45
XP_016876829 (OMIM: 160500,160760,181430,192600,25 (1935) 2510 186.6 2.2e-45
NP_000248 (OMIM: 160500,160760,181430,192600,25516 (1935) 2510 186.6 2.2e-45
NP_060003 (OMIM: 160742) myosin-4 [Homo sapiens]   (1939) 2490 185.3 5.6e-45
XP_016880165 (OMIM: 160742) PREDICTED: myosin-4 is (1939) 2490 185.3 5.6e-45
NP_002462 (OMIM: 160710,192600,613251,613252,61408 (1939) 2457 183.1 2.6e-44
XP_011527249 (OMIM: 609928) PREDICTED: myosin-7B i (1738) 2448 182.4 3.6e-44
XP_011527250 (OMIM: 609928) PREDICTED: myosin-7B i (1738) 2448 182.4 3.6e-44
XP_016883476 (OMIM: 609928) PREDICTED: myosin-7B i (1807) 2448 182.4 3.8e-44
NP_065935 (OMIM: 609928) myosin-7B [Homo sapiens]  (1983) 2448 182.5 4.1e-44
XP_006723903 (OMIM: 609928) PREDICTED: myosin-7B i (1989) 2448 182.5 4.1e-44


>>NP_001139281 (OMIM: 600652,608568,614369) myosin-14 is  (2036 aa)
 initn: 13009 init1: 13009 opt: 13009  Z-score: 4757.2  bits: 893.8 E(85289):    0
Smith-Waterman score: 13009; 100.0% identity (100.0% similar) in 2036 aa overlap (1-2036:1-2036)

               10        20        30        40        50        60
pF1KA2 MAAVTMSVPGRKAPPRPGPVPEAAQPFLFTPRGPSAGGGPGSGTSPQVEWTARRLVWVPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAVTMSVPGRKAPPRPGPVPEAAQPFLFTPRGPSAGGGPGSGTSPQVEWTARRLVWVPS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA2 ELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEAS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA2 VLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA2 AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPASVSTVSYG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPASVSTVSYG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA2 ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAI
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA2 RQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQERELFQETLESL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQERELFQETLESL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA2 RVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFS
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA2 RALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGAS
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA2 FLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA2 DLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQA
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA2 DFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDEHGGFQQFSFLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDEHGGFQQFSFLG
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA2 SFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLS
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA2 RLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQ
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA2 EFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEER
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA2 DLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVK
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA2 PLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAEL
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KA2 CAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAE
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KA2 EGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKV
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KA2 KSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELR
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KA2 AQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRR
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KA2 DLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHG
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KA2 QALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQ
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KA2 EVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQE
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KA2 LLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEE
             1390      1400      1410      1420      1430      1440

             1450      1460      1470      1480      1490      1500
pF1KA2 EAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQL
             1450      1460      1470      1480      1490      1500

             1510      1520      1530      1540      1550      1560
pF1KA2 VSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL
             1510      1520      1530      1540      1550      1560

             1570      1580      1590      1600      1610      1620
pF1KA2 ERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAK
             1570      1580      1590      1600      1610      1620

             1630      1640      1650      1660      1670      1680
pF1KA2 LRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKL
             1630      1640      1650      1660      1670      1680

             1690      1700      1710      1720      1730      1740
pF1KA2 EGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRL
             1690      1700      1710      1720      1730      1740

             1750      1760      1770      1780      1790      1800
pF1KA2 KGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLE
             1750      1760      1770      1780      1790      1800

             1810      1820      1830      1840      1850      1860
pF1KA2 EELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLG
             1810      1820      1830      1840      1850      1860

             1870      1880      1890      1900      1910      1920
pF1KA2 EEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEER
             1870      1880      1890      1900      1910      1920

             1930      1940      1950      1960      1970      1980
pF1KA2 RVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVT
             1930      1940      1950      1960      1970      1980

             1990      2000      2010      2020      2030      
pF1KA2 TLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEAQPGSGPSPEPEGSPPAHPQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEAQPGSGPSPEPEGSPPAHPQ
             1990      2000      2010      2020      2030      

>>NP_079005 (OMIM: 600652,608568,614369) myosin-14 isofo  (1995 aa)
 initn: 9989 init1: 8441 opt: 8442  Z-score: 3094.9  bits: 586.2 E(85289): 1.2e-165
Smith-Waterman score: 12621; 98.0% identity (98.0% similar) in 2036 aa overlap (1-2036:1-1995)

               10        20        30        40        50        60
pF1KA2 MAAVTMSVPGRKAPPRPGPVPEAAQPFLFTPRGPSAGGGPGSGTSPQVEWTARRLVWVPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 MAAVTMSVPGRKAPPRPGPVPEAAQPFLFTPRGPSAGGGPGSGTSPQVEWTARRLVWVPS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA2 ELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 ELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEAS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA2 VLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 VLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA2 AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPASVSTVSYG
       :::::::::::::::::::::::::::::::::::::::::::::::::::        :
NP_079 AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVP--------G
              190       200       210       220       230          

              250       260       270       280       290       300
pF1KA2 ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAI
            240       250       260       270       280       290  

              310       320       330       340       350       360
pF1KA2 RQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQERELFQETLESL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 RQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQERELFQETLESL
            300       310       320       330       340       350  

              370       380       390       400       410       420
pF1KA2 RVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 RVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFS
            360       370       380       390       400       410  

              430       440       450       460       470       480
pF1KA2 RALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 RALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGAS
            420       430       440       450       460       470  

              490       500       510       520       530       540
pF1KA2 FLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 FLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGL
            480       490       500       510       520       530  

              550       560       570       580       590       600
pF1KA2 DLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 DLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQA
            540       550       560       570       580       590  

              610       620       630       640       650       660
pF1KA2 DFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDEHGGFQQFSFLG
       ::::::::::::::::::::::::::::::::::::::::::::::::            
NP_079 DFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKD------------
            600       610       620       630       640            

              670       680       690       700       710       720
pF1KA2 SFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLS
                            :::::::::::::::::::::::::::::::::::::::
NP_079 ---------------------VEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLS
                                   650       660       670         

              730       740       750       760       770       780
pF1KA2 RLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 RLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQ
     680       690       700       710       720       730         

              790       800       810       820       830       840
pF1KA2 EFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 EFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEER
     740       750       760       770       780       790         

              850       860       870       880       890       900
pF1KA2 DLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 DLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVK
     800       810       820       830       840       850         

              910       920       930       940       950       960
pF1KA2 PLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 PLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAEL
     860       870       880       890       900       910         

              970       980       990      1000      1010      1020
pF1KA2 CAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 CAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAE
     920       930       940       950       960       970         

             1030      1040      1050      1060      1070      1080
pF1KA2 EGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 EGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKV
     980       990      1000      1010      1020      1030         

             1090      1100      1110      1120      1130      1140
pF1KA2 KSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 KSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELR
    1040      1050      1060      1070      1080      1090         

             1150      1160      1170      1180      1190      1200
pF1KA2 AQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 AQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRR
    1100      1110      1120      1130      1140      1150         

             1210      1220      1230      1240      1250      1260
pF1KA2 DLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 DLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHG
    1160      1170      1180      1190      1200      1210         

             1270      1280      1290      1300      1310      1320
pF1KA2 QALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 QALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQ
    1220      1230      1240      1250      1260      1270         

             1330      1340      1350      1360      1370      1380
pF1KA2 EVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 EVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQE
    1280      1290      1300      1310      1320      1330         

             1390      1400      1410      1420      1430      1440
pF1KA2 LLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 LLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEE
    1340      1350      1360      1370      1380      1390         

             1450      1460      1470      1480      1490      1500
pF1KA2 EAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 EAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQL
    1400      1410      1420      1430      1440      1450         

             1510      1520      1530      1540      1550      1560
pF1KA2 VSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 VSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL
    1460      1470      1480      1490      1500      1510         

             1570      1580      1590      1600      1610      1620
pF1KA2 ERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 ERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAK
    1520      1530      1540      1550      1560      1570         

             1630      1640      1650      1660      1670      1680
pF1KA2 LRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 LRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKL
    1580      1590      1600      1610      1620      1630         

             1690      1700      1710      1720      1730      1740
pF1KA2 EGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 EGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRL
    1640      1650      1660      1670      1680      1690         

             1750      1760      1770      1780      1790      1800
pF1KA2 KGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 KGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLE
    1700      1710      1720      1730      1740      1750         

             1810      1820      1830      1840      1850      1860
pF1KA2 EELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 EELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLG
    1760      1770      1780      1790      1800      1810         

             1870      1880      1890      1900      1910      1920
pF1KA2 EEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 EEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEER
    1820      1830      1840      1850      1860      1870         

             1930      1940      1950      1960      1970      1980
pF1KA2 RVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 RVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVT
    1880      1890      1900      1910      1920      1930         

             1990      2000      2010      2020      2030      
pF1KA2 TLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEAQPGSGPSPEPEGSPPAHPQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 TLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEAQPGSGPSPEPEGSPPAHPQ
    1940      1950      1960      1970      1980      1990     

>>XP_006723449 (OMIM: 600652,608568,614369) PREDICTED: m  (2003 aa)
 initn: 8441 init1: 8441 opt: 8442  Z-score: 3094.8  bits: 586.2 E(85289): 1.2e-165
Smith-Waterman score: 12690; 98.4% identity (98.4% similar) in 2036 aa overlap (1-2036:1-2003)

               10        20        30        40        50        60
pF1KA2 MAAVTMSVPGRKAPPRPGPVPEAAQPFLFTPRGPSAGGGPGSGTSPQVEWTARRLVWVPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MAAVTMSVPGRKAPPRPGPVPEAAQPFLFTPRGPSAGGGPGSGTSPQVEWTARRLVWVPS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA2 ELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEAS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA2 VLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA2 AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPASVSTVSYG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPASVSTVSYG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA2 ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAI
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA2 RQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQERELFQETLESL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQERELFQETLESL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA2 RVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFS
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA2 RALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGAS
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA2 FLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA2 DLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQA
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA2 DFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDEHGGFQQFSFLG
       ::::::::::::::::::::::::::::::::::::::::::::::::            
XP_006 DFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKD------------
              610       620       630       640                    

              670       680       690       700       710       720
pF1KA2 SFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLS
                            :::::::::::::::::::::::::::::::::::::::
XP_006 ---------------------VEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLS
                           650       660       670       680       

              730       740       750       760       770       780
pF1KA2 RLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQ
       690       700       710       720       730       740       

              790       800       810       820       830       840
pF1KA2 EFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEER
       750       760       770       780       790       800       

              850       860       870       880       890       900
pF1KA2 DLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVK
       810       820       830       840       850       860       

              910       920       930       940       950       960
pF1KA2 PLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAEL
       870       880       890       900       910       920       

              970       980       990      1000      1010      1020
pF1KA2 CAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAE
       930       940       950       960       970       980       

             1030      1040      1050      1060      1070      1080
pF1KA2 EGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKV
       990      1000      1010      1020      1030      1040       

             1090      1100      1110      1120      1130      1140
pF1KA2 KSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELR
      1050      1060      1070      1080      1090      1100       

             1150      1160      1170      1180      1190      1200
pF1KA2 AQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRR
      1110      1120      1130      1140      1150      1160       

             1210      1220      1230      1240      1250      1260
pF1KA2 DLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHG
      1170      1180      1190      1200      1210      1220       

             1270      1280      1290      1300      1310      1320
pF1KA2 QALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQ
      1230      1240      1250      1260      1270      1280       

             1330      1340      1350      1360      1370      1380
pF1KA2 EVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQE
      1290      1300      1310      1320      1330      1340       

             1390      1400      1410      1420      1430      1440
pF1KA2 LLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEE
      1350      1360      1370      1380      1390      1400       

             1450      1460      1470      1480      1490      1500
pF1KA2 EAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQL
      1410      1420      1430      1440      1450      1460       

             1510      1520      1530      1540      1550      1560
pF1KA2 VSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL
      1470      1480      1490      1500      1510      1520       

             1570      1580      1590      1600      1610      1620
pF1KA2 ERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAK
      1530      1540      1550      1560      1570      1580       

             1630      1640      1650      1660      1670      1680
pF1KA2 LRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKL
      1590      1600      1610      1620      1630      1640       

             1690      1700      1710      1720      1730      1740
pF1KA2 EGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRL
      1650      1660      1670      1680      1690      1700       

             1750      1760      1770      1780      1790      1800
pF1KA2 KGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLE
      1710      1720      1730      1740      1750      1760       

             1810      1820      1830      1840      1850      1860
pF1KA2 EELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLG
      1770      1780      1790      1800      1810      1820       

             1870      1880      1890      1900      1910      1920
pF1KA2 EEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEER
      1830      1840      1850      1860      1870      1880       

             1930      1940      1950      1960      1970      1980
pF1KA2 RVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVT
      1890      1900      1910      1920      1930      1940       

             1990      2000      2010      2020      2030      
pF1KA2 TLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEAQPGSGPSPEPEGSPPAHPQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEAQPGSGPSPEPEGSPPAHPQ
      1950      1960      1970      1980      1990      2000   

>>XP_011525625 (OMIM: 600652,608568,614369) PREDICTED: m  (2003 aa)
 initn: 8441 init1: 8441 opt: 8442  Z-score: 3094.8  bits: 586.2 E(85289): 1.2e-165
Smith-Waterman score: 12690; 98.4% identity (98.4% similar) in 2036 aa overlap (1-2036:1-2003)

               10        20        30        40        50        60
pF1KA2 MAAVTMSVPGRKAPPRPGPVPEAAQPFLFTPRGPSAGGGPGSGTSPQVEWTARRLVWVPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAAVTMSVPGRKAPPRPGPVPEAAQPFLFTPRGPSAGGGPGSGTSPQVEWTARRLVWVPS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA2 ELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEAS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA2 VLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA2 AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPASVSTVSYG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPASVSTVSYG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA2 ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAI
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA2 RQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQERELFQETLESL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQERELFQETLESL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA2 RVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFS
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA2 RALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGAS
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA2 FLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA2 DLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQA
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA2 DFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDEHGGFQQFSFLG
       ::::::::::::::::::::::::::::::::::::::::::::::::            
XP_011 DFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKD------------
              610       620       630       640                    

              670       680       690       700       710       720
pF1KA2 SFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLS
                            :::::::::::::::::::::::::::::::::::::::
XP_011 ---------------------VEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLS
                           650       660       670       680       

              730       740       750       760       770       780
pF1KA2 RLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQ
       690       700       710       720       730       740       

              790       800       810       820       830       840
pF1KA2 EFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEER
       750       760       770       780       790       800       

              850       860       870       880       890       900
pF1KA2 DLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVK
       810       820       830       840       850       860       

              910       920       930       940       950       960
pF1KA2 PLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAEL
       870       880       890       900       910       920       

              970       980       990      1000      1010      1020
pF1KA2 CAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAE
       930       940       950       960       970       980       

             1030      1040      1050      1060      1070      1080
pF1KA2 EGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKV
       990      1000      1010      1020      1030      1040       

             1090      1100      1110      1120      1130      1140
pF1KA2 KSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELR
      1050      1060      1070      1080      1090      1100       

             1150      1160      1170      1180      1190      1200
pF1KA2 AQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRR
      1110      1120      1130      1140      1150      1160       

             1210      1220      1230      1240      1250      1260
pF1KA2 DLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHG
      1170      1180      1190      1200      1210      1220       

             1270      1280      1290      1300      1310      1320
pF1KA2 QALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQ
      1230      1240      1250      1260      1270      1280       

             1330      1340      1350      1360      1370      1380
pF1KA2 EVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQE
      1290      1300      1310      1320      1330      1340       

             1390      1400      1410      1420      1430      1440
pF1KA2 LLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEE
      1350      1360      1370      1380      1390      1400       

             1450      1460      1470      1480      1490      1500
pF1KA2 EAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQL
      1410      1420      1430      1440      1450      1460       

             1510      1520      1530      1540      1550      1560
pF1KA2 VSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL
      1470      1480      1490      1500      1510      1520       

             1570      1580      1590      1600      1610      1620
pF1KA2 ERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAK
      1530      1540      1550      1560      1570      1580       

             1630      1640      1650      1660      1670      1680
pF1KA2 LRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKL
      1590      1600      1610      1620      1630      1640       

             1690      1700      1710      1720      1730      1740
pF1KA2 EGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRL
      1650      1660      1670      1680      1690      1700       

             1750      1760      1770      1780      1790      1800
pF1KA2 KGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLE
      1710      1720      1730      1740      1750      1760       

             1810      1820      1830      1840      1850      1860
pF1KA2 EELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLG
      1770      1780      1790      1800      1810      1820       

             1870      1880      1890      1900      1910      1920
pF1KA2 EEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEER
      1830      1840      1850      1860      1870      1880       

             1930      1940      1950      1960      1970      1980
pF1KA2 RVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVT
      1890      1900      1910      1920      1930      1940       

             1990      2000      2010      2020      2030      
pF1KA2 TLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEAQPGSGPSPEPEGSPPAHPQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEAQPGSGPSPEPEGSPPAHPQ
      1950      1960      1970      1980      1990      2000   

>>NP_001070654 (OMIM: 600652,608568,614369) myosin-14 is  (2003 aa)
 initn: 8441 init1: 8441 opt: 8442  Z-score: 3094.8  bits: 586.2 E(85289): 1.2e-165
Smith-Waterman score: 12690; 98.4% identity (98.4% similar) in 2036 aa overlap (1-2036:1-2003)

               10        20        30        40        50        60
pF1KA2 MAAVTMSVPGRKAPPRPGPVPEAAQPFLFTPRGPSAGGGPGSGTSPQVEWTARRLVWVPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAVTMSVPGRKAPPRPGPVPEAAQPFLFTPRGPSAGGGPGSGTSPQVEWTARRLVWVPS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA2 ELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEAS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA2 VLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA2 AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPASVSTVSYG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPASVSTVSYG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA2 ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAI
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA2 RQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQERELFQETLESL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQERELFQETLESL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA2 RVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFS
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA2 RALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGAS
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA2 FLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA2 DLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQA
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA2 DFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDEHGGFQQFSFLG
       ::::::::::::::::::::::::::::::::::::::::::::::::            
NP_001 DFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKD------------
              610       620       630       640                    

              670       680       690       700       710       720
pF1KA2 SFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLS
                            :::::::::::::::::::::::::::::::::::::::
NP_001 ---------------------VEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLS
                           650       660       670       680       

              730       740       750       760       770       780
pF1KA2 RLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQ
       690       700       710       720       730       740       

              790       800       810       820       830       840
pF1KA2 EFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEER
       750       760       770       780       790       800       

              850       860       870       880       890       900
pF1KA2 DLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVK
       810       820       830       840       850       860       

              910       920       930       940       950       960
pF1KA2 PLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAEL
       870       880       890       900       910       920       

              970       980       990      1000      1010      1020
pF1KA2 CAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAE
       930       940       950       960       970       980       

             1030      1040      1050      1060      1070      1080
pF1KA2 EGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKV
       990      1000      1010      1020      1030      1040       

             1090      1100      1110      1120      1130      1140
pF1KA2 KSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELR
      1050      1060      1070      1080      1090      1100       

             1150      1160      1170      1180      1190      1200
pF1KA2 AQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRR
      1110      1120      1130      1140      1150      1160       

             1210      1220      1230      1240      1250      1260
pF1KA2 DLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHG
      1170      1180      1190      1200      1210      1220       

             1270      1280      1290      1300      1310      1320
pF1KA2 QALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQ
      1230      1240      1250      1260      1270      1280       

             1330      1340      1350      1360      1370      1380
pF1KA2 EVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQE
      1290      1300      1310      1320      1330      1340       

             1390      1400      1410      1420      1430      1440
pF1KA2 LLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEE
      1350      1360      1370      1380      1390      1400       

             1450      1460      1470      1480      1490      1500
pF1KA2 EAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQL
      1410      1420      1430      1440      1450      1460       

             1510      1520      1530      1540      1550      1560
pF1KA2 VSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL
      1470      1480      1490      1500      1510      1520       

             1570      1580      1590      1600      1610      1620
pF1KA2 ERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAK
      1530      1540      1550      1560      1570      1580       

             1630      1640      1650      1660      1670      1680
pF1KA2 LRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKL
      1590      1600      1610      1620      1630      1640       

             1690      1700      1710      1720      1730      1740
pF1KA2 EGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRL
      1650      1660      1670      1680      1690      1700       

             1750      1760      1770      1780      1790      1800
pF1KA2 KGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLE
      1710      1720      1730      1740      1750      1760       

             1810      1820      1830      1840      1850      1860
pF1KA2 EELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLG
      1770      1780      1790      1800      1810      1820       

             1870      1880      1890      1900      1910      1920
pF1KA2 EEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEER
      1830      1840      1850      1860      1870      1880       

             1930      1940      1950      1960      1970      1980
pF1KA2 RVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVT
      1890      1900      1910      1920      1930      1940       

             1990      2000      2010      2020      2030      
pF1KA2 TLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEAQPGSGPSPEPEGSPPAHPQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEAQPGSGPSPEPEGSPPAHPQ
      1950      1960      1970      1980      1990      2000   

>>XP_011525623 (OMIM: 600652,608568,614369) PREDICTED: m  (2035 aa)
 initn: 9989 init1: 8441 opt: 8442  Z-score: 3094.7  bits: 586.2 E(85289): 1.2e-165
Smith-Waterman score: 12621; 98.0% identity (98.0% similar) in 2036 aa overlap (1-2036:41-2035)

                                             10        20        30
pF1KA2                               MAAVTMSVPGRKAPPRPGPVPEAAQPFLFT
                                     ::::::::::::::::::::::::::::::
XP_011 AMPGSKEPEANQRWSRSLRTPRPSEGDRQTMAAVTMSVPGRKAPPRPGPVPEAAQPFLFT
               20        30        40        50        60        70

               40        50        60        70        80        90
pF1KA2 PRGPSAGGGPGSGTSPQVEWTARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PRGPSAGGGPGSGTSPQVEWTARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLR
               80        90       100       110       120       130

              100       110       120       130       140       150
pF1KA2 LPRDQIQRMNPPKFSKAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPRDQIQRMNPPKFSKAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQ
              140       150       160       170       180       190

              160       170       180       190       200       210
pF1KA2 LPIYTEAIVEMYRGKKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPIYTEAIVEMYRGKKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKK
              200       210       220       230       240       250

              220       230       240       250       260       270
pF1KA2 VIQYLAHVASSPKGRKEPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRF
       :::::::::::::::::::::        :::::::::::::::::::::::::::::::
XP_011 VIQYLAHVASSPKGRKEPGVP--------GELERQLLQANPILEAFGNAKTVKNDNSSRF
              260       270               280       290       300  

              280       290       300       310       320       330
pF1KA2 GKFIRINFDVAGYIVGANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GKFIRINFDVAGYIVGANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLE
            310       320       330       340       350       360  

              340       350       360       370       380       390
pF1KA2 PCSHYRFLTNGPSSSPGQERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PCSHYRFLTNGPSSSPGQERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKR
            370       380       390       400       410       420  

              400       410       420       430       440       450
pF1KA2 ERNTDQATMPDNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERNTDQATMPDNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEA
            430       440       450       460       470       480  

              460       470       480       490       500       510
pF1KA2 LAKATYERLFRWLVLRLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAKATYERLFRWLVLRLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKL
            490       500       510       520       530       540  

              520       530       540       550       560       570
pF1KA2 QQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPK
            550       560       570       580       590       600  

              580       590       600       610       620       630
pF1KA2 ATDKSFVEKVAQEQGGHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ATDKSFVEKVAQEQGGHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNV
            610       620       630       640       650       660  

              640       650       660       670       680       690
pF1KA2 AALLHQSTDRLTAEIWKDEHGGFQQFSFLGSFPPSPPGSAERCSSAISPPGVEGIVGLEQ
       ::::::::::::::::::                                 :::::::::
XP_011 AALLHQSTDRLTAEIWKD---------------------------------VEGIVGLEQ
            670       680                                          

              700       710       720       730       740       750
pF1KA2 VSSLGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSSLGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEP
     690       700       710       720       730       740         

              760       770       780       790       800       810
pF1KA2 RLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQACEKMIQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQACEKMIQ
     750       760       770       780       790       800         

              820       830       840       850       860       870
pF1KA2 ALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQ
     810       820       830       840       850       860         

              880       890       900       910       920       930
pF1KA2 QSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSA
     870       880       890       900       910       920         

              940       950       960       970       980       990
pF1KA2 REVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVG
     930       940       950       960       970       980         

             1000      1010      1020      1030      1040      1050
pF1KA2 EEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLED
     990      1000      1010      1020      1030      1040         

             1060      1070      1080      1090      1100      1110
pF1KA2 QNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQE
    1050      1060      1070      1080      1090      1100         

             1120      1130      1140      1150      1160      1170
pF1KA2 LEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKS
    1110      1120      1130      1140      1150      1160         

             1180      1190      1200      1210      1220      1230
pF1KA2 LREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKR
    1170      1180      1190      1200      1210      1220         

             1240      1250      1260      1270      1280      1290
pF1KA2 EQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAE
    1230      1240      1250      1260      1270      1280         

             1300      1310      1320      1330      1340      1350
pF1KA2 VSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENV
    1290      1300      1310      1320      1330      1340         

             1360      1370      1380      1390      1400      1410
pF1KA2 SGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQL
    1350      1360      1370      1380      1390      1400         

             1420      1430      1440      1450      1460      1470
pF1KA2 EEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKT
    1410      1420      1430      1440      1450      1460         

             1480      1490      1500      1510      1520      1530
pF1KA2 ETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERE
    1470      1480      1490      1500      1510      1520         

             1540      1550      1560      1570      1580      1590
pF1KA2 RAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELER
    1530      1540      1550      1560      1570      1580         

             1600      1610      1620      1630      1640      1650
pF1KA2 ACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRR
    1590      1600      1610      1620      1630      1640         

             1660      1670      1680      1690      1700      1710
pF1KA2 QLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQA
    1650      1660      1670      1680      1690      1700         

             1720      1730      1740      1750      1760      1770
pF1KA2 QMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDE
    1710      1720      1730      1740      1750      1760         

             1780      1790      1800      1810      1820      1830
pF1KA2 MADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTE
    1770      1780      1790      1800      1810      1820         

             1840      1850      1860      1870      1880      1890
pF1KA2 LSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQ
    1830      1840      1850      1860      1870      1880         

             1900      1910      1920      1930      1940      1950
pF1KA2 ETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEE
    1890      1900      1910      1920      1930      1940         

             1960      1970      1980      1990      2000      2010
pF1KA2 ASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVAS
    1950      1960      1970      1980      1990      2000         

             2020      2030      
pF1KA2 DEEAEEAQPGSGPSPEPEGSPPAHPQ
       ::::::::::::::::::::::::::
XP_011 DEEAEEAQPGSGPSPEPEGSPPAHPQ
    2010      2020      2030     

>>XP_011525622 (OMIM: 600652,608568,614369) PREDICTED: m  (2043 aa)
 initn: 8441 init1: 8441 opt: 8442  Z-score: 3094.7  bits: 586.2 E(85289): 1.2e-165
Smith-Waterman score: 12690; 98.4% identity (98.4% similar) in 2036 aa overlap (1-2036:41-2043)

                                             10        20        30
pF1KA2                               MAAVTMSVPGRKAPPRPGPVPEAAQPFLFT
                                     ::::::::::::::::::::::::::::::
XP_011 AMPGSKEPEANQRWSRSLRTPRPSEGDRQTMAAVTMSVPGRKAPPRPGPVPEAAQPFLFT
               20        30        40        50        60        70

               40        50        60        70        80        90
pF1KA2 PRGPSAGGGPGSGTSPQVEWTARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PRGPSAGGGPGSGTSPQVEWTARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLR
               80        90       100       110       120       130

              100       110       120       130       140       150
pF1KA2 LPRDQIQRMNPPKFSKAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPRDQIQRMNPPKFSKAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQ
              140       150       160       170       180       190

              160       170       180       190       200       210
pF1KA2 LPIYTEAIVEMYRGKKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPIYTEAIVEMYRGKKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKK
              200       210       220       230       240       250

              220       230       240       250       260       270
pF1KA2 VIQYLAHVASSPKGRKEPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VIQYLAHVASSPKGRKEPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRF
              260       270       280       290       300       310

              280       290       300       310       320       330
pF1KA2 GKFIRINFDVAGYIVGANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GKFIRINFDVAGYIVGANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLE
              320       330       340       350       360       370

              340       350       360       370       380       390
pF1KA2 PCSHYRFLTNGPSSSPGQERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PCSHYRFLTNGPSSSPGQERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKR
              380       390       400       410       420       430

              400       410       420       430       440       450
pF1KA2 ERNTDQATMPDNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERNTDQATMPDNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEA
              440       450       460       470       480       490

              460       470       480       490       500       510
pF1KA2 LAKATYERLFRWLVLRLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAKATYERLFRWLVLRLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKL
              500       510       520       530       540       550

              520       530       540       550       560       570
pF1KA2 QQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPK
              560       570       580       590       600       610

              580       590       600       610       620       630
pF1KA2 ATDKSFVEKVAQEQGGHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ATDKSFVEKVAQEQGGHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNV
              620       630       640       650       660       670

              640       650       660       670       680       690
pF1KA2 AALLHQSTDRLTAEIWKDEHGGFQQFSFLGSFPPSPPGSAERCSSAISPPGVEGIVGLEQ
       ::::::::::::::::::                                 :::::::::
XP_011 AALLHQSTDRLTAEIWKD---------------------------------VEGIVGLEQ
              680                                        690       

              700       710       720       730       740       750
pF1KA2 VSSLGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSSLGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEP
       700       710       720       730       740       750       

              760       770       780       790       800       810
pF1KA2 RLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQACEKMIQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQACEKMIQ
       760       770       780       790       800       810       

              820       830       840       850       860       870
pF1KA2 ALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQ
       820       830       840       850       860       870       

              880       890       900       910       920       930
pF1KA2 QSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSA
       880       890       900       910       920       930       

              940       950       960       970       980       990
pF1KA2 REVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVG
       940       950       960       970       980       990       

             1000      1010      1020      1030      1040      1050
pF1KA2 EEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLED
      1000      1010      1020      1030      1040      1050       

             1060      1070      1080      1090      1100      1110
pF1KA2 QNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQE
      1060      1070      1080      1090      1100      1110       

             1120      1130      1140      1150      1160      1170
pF1KA2 LEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKS
      1120      1130      1140      1150      1160      1170       

             1180      1190      1200      1210      1220      1230
pF1KA2 LREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKR
      1180      1190      1200      1210      1220      1230       

             1240      1250      1260      1270      1280      1290
pF1KA2 EQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAE
      1240      1250      1260      1270      1280      1290       

             1300      1310      1320      1330      1340      1350
pF1KA2 VSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENV
      1300      1310      1320      1330      1340      1350       

             1360      1370      1380      1390      1400      1410
pF1KA2 SGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQL
      1360      1370      1380      1390      1400      1410       

             1420      1430      1440      1450      1460      1470
pF1KA2 EEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKT
      1420      1430      1440      1450      1460      1470       

             1480      1490      1500      1510      1520      1530
pF1KA2 ETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERE
      1480      1490      1500      1510      1520      1530       

             1540      1550      1560      1570      1580      1590
pF1KA2 RAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELER
      1540      1550      1560      1570      1580      1590       

             1600      1610      1620      1630      1640      1650
pF1KA2 ACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRR
      1600      1610      1620      1630      1640      1650       

             1660      1670      1680      1690      1700      1710
pF1KA2 QLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQA
      1660      1670      1680      1690      1700      1710       

             1720      1730      1740      1750      1760      1770
pF1KA2 QMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDE
      1720      1730      1740      1750      1760      1770       

             1780      1790      1800      1810      1820      1830
pF1KA2 MADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTE
      1780      1790      1800      1810      1820      1830       

             1840      1850      1860      1870      1880      1890
pF1KA2 LSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQ
      1840      1850      1860      1870      1880      1890       

             1900      1910      1920      1930      1940      1950
pF1KA2 ETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEE
      1900      1910      1920      1930      1940      1950       

             1960      1970      1980      1990      2000      2010
pF1KA2 ASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVAS
      1960      1970      1980      1990      2000      2010       

             2020      2030      
pF1KA2 DEEAEEAQPGSGPSPEPEGSPPAHPQ
       ::::::::::::::::::::::::::
XP_011 DEEAEEAQPGSGPSPEPEGSPPAHPQ
      2020      2030      2040   

>>NP_001242941 (OMIM: 160776) myosin-10 isoform 1 [Homo   (2007 aa)
 initn: 8061 init1: 5325 opt: 6225  Z-score: 2287.8  bits: 436.9 E(85289): 1.1e-120
Smith-Waterman score: 8689; 66.4% identity (88.6% similar) in 1996 aa overlap (47-2032:27-2004)

         20        30        40        50        60        70      
pF1KA2 PGPVPEAAQPFLFTPRGPSAGGGPGSGTSPQVEWTARRLVWVPSELHGFEAAALRDEGEE
                                     :..:::..:::.::: ::::::....:  .
NP_001     MAQRTGLEDPERYLFVDRAVIYNPATQADWTAKKLVWIPSERHGFEAASIKEERGD
                   10        20        30        40        50      

         80        90       100       110       120       130      
pF1KA2 EAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEASVLHNLRERYYSGLIYT
       :. :::::.:..  . .:.::.::::::::.::::::::::::::::::..:::::::::
NP_001 EVMVELAENGKKAMVNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKDRYYSGLIYT
         60        70        80        90       100       110      

        140       150       160       170       180       190      
pF1KA2 YSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEGAYRSMLQDREDQSILC
       :::::::::::::.::::.: :.::::::::::.:::.::..:.::: ::::::::::::
NP_001 YSGLFCVVINPYKNLPIYSENIIEMYRGKKRHEMPPHIYAISESAYRCMLQDREDQSILC
        120       130       140       150       160       170      

        200       210       220       230         240       250    
pF1KA2 TGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPA-SVSTVSY-GELERQLLQANPILE
       ::::::::::::::::::::::::: ::::. ..:  : . :.. :::::::::::::::
NP_001 TGESGAGKTENTKKVIQYLAHVASSHKGRKDHNIPQESPKPVKHQGELERQLLQANPILE
        180       190       200       210       220       230      

          260       270       280       290       300       310    
pF1KA2 AFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAIRQAKDECSFHIFYQ
       .:::::::::::::::::::::::::.::::::::::::::::::.:::::: .::::::
NP_001 SFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAVRQAKDERTFHIFYQ
        240       250       260       270       280       290      

          320       330       340        350       360       370   
pF1KA2 LLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQE-RELFQETLESLRVLGFSHEEIISM
       ::.::::.::.:::::  ..::::.::    :::. .. ::::.:.....:::::::.::
NP_001 LLSGAGEHLKSDLLLEGFNNYRFLSNGYIPIPGQQDKDNFQETMEAMHIMGFSHEEILSM
        300       310       320       330       340       350      

           380       390       400       410       420       430   
pF1KA2 LRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRD
       :..::.:::::::..:.:::::::.::.::.:::::.:::..: .:.::.::::::::::
NP_001 LKVVSSVLQFGNISFKKERNTDQASMPENTVAQKLCHLLGMNVMEFTRAILTPRIKVGRD
        360       370       380       390       400       410      

           440       450       460       470       480       490   
pF1KA2 YVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGASFLGILDIAGFEIF
       ::::::::::::::.:::::::::::::::: :.:.::::. ::::::.:::::::::::
NP_001 YVQKAQTKEQADFAVEALAKATYERLFRWLVHRINKALDRTKRQGASFIGILDIAGFEIF
        420       430       440       450       460       470      

           500       510       520       530       540       550   
pF1KA2 QLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPA
       .:::::::::::::::::::::::::.::::::::::: :.:.:::::::::::::::::
NP_001 ELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIERPA
        480       490       500       510       520       530      

           560       570       580       590       600       610   
pF1KA2 NPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQADFSVLHYAGKVDY
       ::::.::::::::::::::::.::::..::::.: :::.::.:.:.::: ..::::::::
NP_001 NPPGVLALLDEECWFPKATDKTFVEKLVQEQGSHSKFQKPRQLKDKADFCIIHYAGKVDY
        540       550       560       570       580       590      

           620       630       640       650       660       670   
pF1KA2 KANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDEHGGFQQFSFLGSFPPSPPGSAERC
       ::.:::::::::::::::.:::::.::..::.::::  ..:. ::  :            
NP_001 KADEWLMKNMDPLNDNVATLLHQSSDRFVAELWKDEIQNIQRASFYDSV-----------
        600       610       620       630       640                

           680       690       700         710       720       730 
pF1KA2 SSAISPPGVEGIVGLEQVSSLGDGPPGG--RPRRGMFRTVGQLYKESLSRLMATLSNTNP
        :..  : :. ::::.::... .   :.  . ..::::::::::::::..::::: ::::
NP_001 -SGLHEPPVDRIVGLDQVTGMTETAFGSAYKTKKGMFRTVGQLYKESLTKLMATLRNTNP
          650       660       670       680       690       700    

             740       750       760       770       780       790 
pF1KA2 SFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTP
       .:::::.::::::::::.:.::::::::::::::::::::::::::.:::::::::::::
NP_001 NFVRCIIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILTP
          710       720       730       740       750       760    

             800       810       820       830       840       850 
pF1KA2 NAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSF
       :::::::::::::::.::.::::::::::.:::::::::::::.::::::::.::::. :
NP_001 NAIPKGFMDGKQACERMIRALELDPNLYRIGQSKIFFRAGVLAHLEEERDLKITDIIIFF
          770       780       790       800       810       820    

             860       870       880       890       900       910 
pF1KA2 QAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEV
       ::. ::::::.:: :.::: :::.:.:::::::::::::::::.:::::::::::::.: 
NP_001 QAVCRGYLARKAFAKKQQQLSALKVLQRNCAAYLKLRHWQWWRVFTKVKPLLQVTRQEEE
          830       840       850       860       870       880    

             920       930       940       950       960       970 
pF1KA2 LQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRL
       :::. .:: ::.: : .   :. :.. .  :: ::.  :::::.::.:: ::::: :.::
NP_001 LQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARL
          890       900       910       920       930       940    

             980       990      1000      1010      1020      1030 
pF1KA2 AARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEK
       ::.::::: .. .::.:: :::: .. .:.:::..: :::.:: .:. ::::::::::::
NP_001 AAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEK
          950       960       970       980       990      1000    

            1040      1050      1060      1070      1080      1090 
pF1KA2 VTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYE
       ::.:::.::.::..:::::::::. ::.::.:::.:: ::: ::::::.:.: :.: : :
NP_001 VTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQE
         1010      1020      1030      1040      1050      1060    

            1100      1110      1120      1130      1140      1150 
pF1KA2 ATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQ
       . :.:.:.::.:::: :::::: ::.::::...::.:..: : . .::. ::..::::::
NP_001 VMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQ
         1070      1080      1090      1100      1110      1120    

            1160      1170      1180      1190      1200      1210 
pF1KA2 AALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRG
       .::::..::   . . :: .:: :: .:: :::.:::...:.:::::.:::.::::::. 
NP_001 GALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKT
         1130      1140      1150      1160      1170      1180    

            1220      1230      1240      1250      1260      1270 
pF1KA2 ELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLE
       :::::::.: ::::::.::::::.::::.:::::. ::: .:..::::. :: ::.::::
NP_001 ELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLE
         1190      1200      1210      1220      1230      1240    

            1280      1290      1300      1310      1320      1330 
pF1KA2 QARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGER
       ::.: :.  ::.. .::.. .::  :.. :: .. :.:..:..:. :.::.......:.:
NP_001 QAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDR
         1250      1260      1270      1280      1290      1300    

            1340      1350      1360      1370      1380      1390 
pF1KA2 ARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLA
        :.: ::: .. : ::.:::  :.:::.: :...:. .: :.::.:.::::::::: :: 
NP_001 LRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLN
         1310      1320      1330      1340      1350      1360    

            1400      1410      1420      1430      1440      1450 
pF1KA2 LGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEA
       :.::.: .: :  .:.:: :::  ::.   ... . :.::.. ... ... :..:. :::
NP_001 LSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEA
         1370      1380      1390      1400      1410      1420    

            1460      1470      1480      1490      1500      1510 
pF1KA2 RRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKF
       ...  ..::::.::: ::. . :.::. . :::::::: :.::..:::..:.:::::.::
NP_001 KKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKF
         1430      1440      1450      1460      1470      1480    

            1520      1530      1540      1550      1560      1570 
pF1KA2 DQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAEL
       ::::::::.   : .:::.:::::.::.:..::::.:::::  ::.::.::::. :::..
NP_001 DQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADM
         1490      1500      1510      1520      1530      1540    

            1580      1590      1600      1610      1620      1630 
pF1KA2 EALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALK
       : :.::::::::.:::::.. :. :: ....:.:. :::::: :.:::::::::..::.:
NP_001 EDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMK
         1550      1560      1570      1580      1590      1600    

            1640      1650      1660      1670      1680      1690 
pF1KA2 TQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQM
       .: ::::: ::: .::..: : ::.:. :.: ..:::::.::::..::.: .:..:.::.
NP_001 AQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQI
         1610      1620      1630      1640      1650      1660    

            1700      1710      1720      1730      1740      1750 
pF1KA2 ASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQ
        .:.....:..:::::.:::::.  ::.::.:.::.:::.:..::::.::.::::.:.::
NP_001 EAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQ
         1670      1680      1690      1700      1710      1720    

            1760      1770      1780      1790      1800      1810 
pF1KA2 EELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSE
       ::::.:.::::.:.:.:::.:::..:.  .:.:.:.:::.::.:..:::::::::::: :
NP_001 EELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNME
         1730      1740      1750      1760      1770      1780    

            1820      1830      1840      1850      1860      1870 
pF1KA2 LLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHK
       :::::.::  :::..:..::.:::: . :....::::::: .::...: : ....... :
NP_001 LLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFK
         1790      1800      1810      1820      1830      1840    

            1880      1890      1900      1910      1920      1930 
pF1KA2 MTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLE
        ::.:::.:..: :::::::..::  ..:::::.::.:::. .:::.::: ::: ..:.:
NP_001 ATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQME
         1850      1860      1870      1880      1890      1900    

            1940      1950      1960      1970      1980       1990
pF1KA2 KGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRG-P
       :.: :.::::::::::::::.::.:.::.:::::.:.::. :...:::.::.:::::: :
NP_001 KANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLRRGGP
         1910      1920      1930      1940      1950      1960    

              2000         2010      2020      2030      
pF1KA2 LTFTT-RTVRQVFRLEEGVA---SDEEAEEAQPGSGPSPEPEGSPPAHPQ
       ..:.. :. :. ..:: :..   ::...:     :  :   : .::    
NP_001 ISFSSSRSGRRQLHLE-GASLELSDDDTE-----SKTSDVNETQPPQSE 
         1970      1980       1990           2000        

>>XP_011522177 (OMIM: 160776) PREDICTED: myosin-10 isofo  (2037 aa)
 initn: 8061 init1: 5325 opt: 6225  Z-score: 2287.7  bits: 436.9 E(85289): 1.1e-120
Smith-Waterman score: 8689; 66.4% identity (88.6% similar) in 1996 aa overlap (47-2032:57-2034)

         20        30        40        50        60        70      
pF1KA2 PGPVPEAAQPFLFTPRGPSAGGGPGSGTSPQVEWTARRLVWVPSELHGFEAAALRDEGEE
                                     :..:::..:::.::: ::::::....:  .
XP_011 VPFTMAQRTGLEDPERYLFVDRAVIYNPATQADWTAKKLVWIPSERHGFEAASIKEERGD
         30        40        50        60        70        80      

         80        90       100       110       120       130      
pF1KA2 EAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEASVLHNLRERYYSGLIYT
       :. :::::.:..  . .:.::.::::::::.::::::::::::::::::..:::::::::
XP_011 EVMVELAENGKKAMVNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKDRYYSGLIYT
         90       100       110       120       130       140      

        140       150       160       170       180       190      
pF1KA2 YSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEGAYRSMLQDREDQSILC
       :::::::::::::.::::.: :.::::::::::.:::.::..:.::: ::::::::::::
XP_011 YSGLFCVVINPYKNLPIYSENIIEMYRGKKRHEMPPHIYAISESAYRCMLQDREDQSILC
        150       160       170       180       190       200      

        200       210       220       230         240       250    
pF1KA2 TGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPA-SVSTVSY-GELERQLLQANPILE
       ::::::::::::::::::::::::: ::::. ..:  : . :.. :::::::::::::::
XP_011 TGESGAGKTENTKKVIQYLAHVASSHKGRKDHNIPQESPKPVKHQGELERQLLQANPILE
        210       220       230       240       250       260      

          260       270       280       290       300       310    
pF1KA2 AFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAIRQAKDECSFHIFYQ
       .:::::::::::::::::::::::::.::::::::::::::::::.:::::: .::::::
XP_011 SFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAVRQAKDERTFHIFYQ
        270       280       290       300       310       320      

          320       330       340        350       360       370   
pF1KA2 LLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQE-RELFQETLESLRVLGFSHEEIISM
       ::.::::.::.:::::  ..::::.::    :::. .. ::::.:.....:::::::.::
XP_011 LLSGAGEHLKSDLLLEGFNNYRFLSNGYIPIPGQQDKDNFQETMEAMHIMGFSHEEILSM
        330       340       350       360       370       380      

           380       390       400       410       420       430   
pF1KA2 LRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRD
       :..::.:::::::..:.:::::::.::.::.:::::.:::..: .:.::.::::::::::
XP_011 LKVVSSVLQFGNISFKKERNTDQASMPENTVAQKLCHLLGMNVMEFTRAILTPRIKVGRD
        390       400       410       420       430       440      

           440       450       460       470       480       490   
pF1KA2 YVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGASFLGILDIAGFEIF
       ::::::::::::::.:::::::::::::::: :.:.::::. ::::::.:::::::::::
XP_011 YVQKAQTKEQADFAVEALAKATYERLFRWLVHRINKALDRTKRQGASFIGILDIAGFEIF
        450       460       470       480       490       500      

           500       510       520       530       540       550   
pF1KA2 QLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPA
       .:::::::::::::::::::::::::.::::::::::: :.:.:::::::::::::::::
XP_011 ELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIERPA
        510       520       530       540       550       560      

           560       570       580       590       600       610   
pF1KA2 NPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQADFSVLHYAGKVDY
       ::::.::::::::::::::::.::::..::::.: :::.::.:.:.::: ..::::::::
XP_011 NPPGVLALLDEECWFPKATDKTFVEKLVQEQGSHSKFQKPRQLKDKADFCIIHYAGKVDY
        570       580       590       600       610       620      

           620       630       640       650       660       670   
pF1KA2 KANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDEHGGFQQFSFLGSFPPSPPGSAERC
       ::.:::::::::::::::.:::::.::..::.::::  ..:. ::  :            
XP_011 KADEWLMKNMDPLNDNVATLLHQSSDRFVAELWKDEIQNIQRASFYDSV-----------
        630       640       650       660       670                

           680       690       700         710       720       730 
pF1KA2 SSAISPPGVEGIVGLEQVSSLGDGPPGG--RPRRGMFRTVGQLYKESLSRLMATLSNTNP
        :..  : :. ::::.::... .   :.  . ..::::::::::::::..::::: ::::
XP_011 -SGLHEPPVDRIVGLDQVTGMTETAFGSAYKTKKGMFRTVGQLYKESLTKLMATLRNTNP
          680       690       700       710       720       730    

             740       750       760       770       780       790 
pF1KA2 SFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTP
       .:::::.::::::::::.:.::::::::::::::::::::::::::.:::::::::::::
XP_011 NFVRCIIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILTP
          740       750       760       770       780       790    

             800       810       820       830       840       850 
pF1KA2 NAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSF
       :::::::::::::::.::.::::::::::.:::::::::::::.::::::::.::::. :
XP_011 NAIPKGFMDGKQACERMIRALELDPNLYRIGQSKIFFRAGVLAHLEEERDLKITDIIIFF
          800       810       820       830       840       850    

             860       870       880       890       900       910 
pF1KA2 QAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEV
       ::. ::::::.:: :.::: :::.:.:::::::::::::::::.:::::::::::::.: 
XP_011 QAVCRGYLARKAFAKKQQQLSALKVLQRNCAAYLKLRHWQWWRVFTKVKPLLQVTRQEEE
          860       870       880       890       900       910    

             920       930       940       950       960       970 
pF1KA2 LQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRL
       :::. .:: ::.: : .   :. :.. .  :: ::.  :::::.::.:: ::::: :.::
XP_011 LQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARL
          920       930       940       950       960       970    

             980       990      1000      1010      1020      1030 
pF1KA2 AARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEK
       ::.::::: .. .::.:: :::: .. .:.:::..: :::.:: .:. ::::::::::::
XP_011 AAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEK
          980       990      1000      1010      1020      1030    

            1040      1050      1060      1070      1080      1090 
pF1KA2 VTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYE
       ::.:::.::.::..:::::::::. ::.::.:::.:: ::: ::::::.:.: :.: : :
XP_011 VTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQE
         1040      1050      1060      1070      1080      1090    

            1100      1110      1120      1130      1140      1150 
pF1KA2 ATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQ
       . :.:.:.::.:::: :::::: ::.::::...::.:..: : . .::. ::..::::::
XP_011 VMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQ
         1100      1110      1120      1130      1140      1150    

            1160      1170      1180      1190      1200      1210 
pF1KA2 AALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRG
       .::::..::   . . :: .:: :: .:: :::.:::...:.:::::.:::.::::::. 
XP_011 GALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKT
         1160      1170      1180      1190      1200      1210    

            1220      1230      1240      1250      1260      1270 
pF1KA2 ELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLE
       :::::::.: ::::::.::::::.::::.:::::. ::: .:..::::. :: ::.::::
XP_011 ELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLE
         1220      1230      1240      1250      1260      1270    

            1280      1290      1300      1310      1320      1330 
pF1KA2 QARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGER
       ::.: :.  ::.. .::.. .::  :.. :: .. :.:..:..:. :.::.......:.:
XP_011 QAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDR
         1280      1290      1300      1310      1320      1330    

            1340      1350      1360      1370      1380      1390 
pF1KA2 ARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLA
        :.: ::: .. : ::.:::  :.:::.: :...:. .: :.::.:.::::::::: :: 
XP_011 LRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLN
         1340      1350      1360      1370      1380      1390    

            1400      1410      1420      1430      1440      1450 
pF1KA2 LGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEA
       :.::.: .: :  .:.:: :::  ::.   ... . :.::.. ... ... :..:. :::
XP_011 LSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEA
         1400      1410      1420      1430      1440      1450    

            1460      1470      1480      1490      1500      1510 
pF1KA2 RRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKF
       ...  ..::::.::: ::. . :.::. . :::::::: :.::..:::..:.:::::.::
XP_011 KKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKF
         1460      1470      1480      1490      1500      1510    

            1520      1530      1540      1550      1560      1570 
pF1KA2 DQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAEL
       ::::::::.   : .:::.:::::.::.:..::::.:::::  ::.::.::::. :::..
XP_011 DQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADM
         1520      1530      1540      1550      1560      1570    

            1580      1590      1600      1610      1620      1630 
pF1KA2 EALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALK
       : :.::::::::.:::::.. :. :: ....:.:. :::::: :.:::::::::..::.:
XP_011 EDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMK
         1580      1590      1600      1610      1620      1630    

            1640      1650      1660      1670      1680      1690 
pF1KA2 TQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQM
       .: ::::: ::: .::..: : ::.:. :.: ..:::::.::::..::.: .:..:.::.
XP_011 AQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQI
         1640      1650      1660      1670      1680      1690    

            1700      1710      1720      1730      1740      1750 
pF1KA2 ASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQ
        .:.....:..:::::.:::::.  ::.::.:.::.:::.:..::::.::.::::.:.::
XP_011 EAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQ
         1700      1710      1720      1730      1740      1750    

            1760      1770      1780      1790      1800      1810 
pF1KA2 EELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSE
       ::::.:.::::.:.:.:::.:::..:.  .:.:.:.:::.::.:..:::::::::::: :
XP_011 EELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNME
         1760      1770      1780      1790      1800      1810    

            1820      1830      1840      1850      1860      1870 
pF1KA2 LLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHK
       :::::.::  :::..:..::.:::: . :....::::::: .::...: : ....... :
XP_011 LLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFK
         1820      1830      1840      1850      1860      1870    

            1880      1890      1900      1910      1920      1930 
pF1KA2 MTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLE
        ::.:::.:..: :::::::..::  ..:::::.::.:::. .:::.::: ::: ..:.:
XP_011 ATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQME
         1880      1890      1900      1910      1920      1930    

            1940      1950      1960      1970      1980       1990
pF1KA2 KGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRG-P
       :.: :.::::::::::::::.::.:.::.:::::.:.::. :...:::.::.:::::: :
XP_011 KANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLRRGGP
         1940      1950      1960      1970      1980      1990    

              2000         2010      2020      2030      
pF1KA2 LTFTT-RTVRQVFRLEEGVA---SDEEAEEAQPGSGPSPEPEGSPPAHPQ
       ..:.. :. :. ..:: :..   ::...:     :  :   : .::    
XP_011 ISFSSSRSGRRQLHLE-GASLELSDDDTE-----SKTSDVNETQPPQSE 
         2000      2010       2020           2030        

>>NP_005955 (OMIM: 160776) myosin-10 isoform 2 [Homo sap  (1976 aa)
 initn: 8040 init1: 5325 opt: 5391  Z-score: 1984.3  bits: 380.7 E(85289): 8.6e-104
Smith-Waterman score: 8605; 66.0% identity (87.8% similar) in 1994 aa overlap (47-2032:27-1973)

         20        30        40        50        60        70      
pF1KA2 PGPVPEAAQPFLFTPRGPSAGGGPGSGTSPQVEWTARRLVWVPSELHGFEAAALRDEGEE
                                     :..:::..:::.::: ::::::....:  .
NP_005     MAQRTGLEDPERYLFVDRAVIYNPATQADWTAKKLVWIPSERHGFEAASIKEERGD
                   10        20        30        40        50      

         80        90       100       110       120       130      
pF1KA2 EAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEASVLHNLRERYYSGLIYT
       :. :::::.:..  . .:.::.::::::::.::::::::::::::::::..:::::::::
NP_005 EVMVELAENGKKAMVNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKDRYYSGLIYT
         60        70        80        90       100       110      

        140       150       160       170       180       190      
pF1KA2 YSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEGAYRSMLQDREDQSILC
       :::::::::::::.::::.: :.::::::::::.:::.::..:.::: ::::::::::::
NP_005 YSGLFCVVINPYKNLPIYSENIIEMYRGKKRHEMPPHIYAISESAYRCMLQDREDQSILC
        120       130       140       150       160       170      

        200       210       220       230       240       250      
pF1KA2 TGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPASVSTVSYGELERQLLQANPILEAF
       ::::::::::::::::::::::::: ::::. ..:        :::::::::::::::.:
NP_005 TGESGAGKTENTKKVIQYLAHVASSHKGRKDHNIP--------GELERQLLQANPILESF
        180       190       200       210               220        

        260       270       280       290       300       310      
pF1KA2 GNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAIRQAKDECSFHIFYQLL
       ::::::::::::::::::::::::.::::::::::::::::::.:::::: .::::::::
NP_005 GNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAVRQAKDERTFHIFYQLL
      230       240       250       260       270       280        

        320       330       340        350       360       370     
pF1KA2 GGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQE-RELFQETLESLRVLGFSHEEIISMLR
       .::::.::.:::::  ..::::.::    :::. .. ::::.:.....:::::::.:::.
NP_005 SGAGEHLKSDLLLEGFNNYRFLSNGYIPIPGQQDKDNFQETMEAMHIMGFSHEEILSMLK
      290       300       310       320       330       340        

         380       390       400       410       420       430     
pF1KA2 MVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYV
       .::.:::::::..:.:::::::.::.::.:::::.:::..: .:.::.::::::::::::
NP_005 VVSSVLQFGNISFKKERNTDQASMPENTVAQKLCHLLGMNVMEFTRAILTPRIKVGRDYV
      350       360       370       380       390       400        

         440       450       460       470       480       490     
pF1KA2 QKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGASFLGILDIAGFEIFQL
       ::::::::::::.:::::::::::::::: :.:.::::. ::::::.:::::::::::.:
NP_005 QKAQTKEQADFAVEALAKATYERLFRWLVHRINKALDRTKRQGASFIGILDIAGFEIFEL
      410       420       430       440       450       460        

         500       510       520       530       540       550     
pF1KA2 NSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANP
       ::::::::::::::::::::::::.::::::::::: :.:.:::::::::::::::::::
NP_005 NSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIERPANP
      470       480       490       500       510       520        

         560       570       580       590       600       610     
pF1KA2 PGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQADFSVLHYAGKVDYKA
       ::.::::::::::::::::.::::..::::.: :::.::.:.:.::: ..::::::::::
NP_005 PGVLALLDEECWFPKATDKTFVEKLVQEQGSHSKFQKPRQLKDKADFCIIHYAGKVDYKA
      530       540       550       560       570       580        

         620       630       640       650       660       670     
pF1KA2 NEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDEHGGFQQFSFLGSFPPSPPGSAERCSS
       .:::::::::::::::.:::::.::..::.:::                           
NP_005 DEWLMKNMDPLNDNVATLLHQSSDRFVAELWKD---------------------------
      590       600       610       620                            

         680       690       700         710       720       730   
pF1KA2 AISPPGVEGIVGLEQVSSLGDGPPGG--RPRRGMFRTVGQLYKESLSRLMATLSNTNPSF
             :. ::::.::... .   :.  . ..::::::::::::::..::::: ::::.:
NP_005 ------VDRIVGLDQVTGMTETAFGSAYKTKKGMFRTVGQLYKESLTKLMATLRNTNPNF
                   630       640       650       660       670     

           740       750       760       770       780       790   
pF1KA2 VRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNA
       ::::.::::::::::.:.::::::::::::::::::::::::::.:::::::::::::::
NP_005 VRCIIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILTPNA
         680       690       700       710       720       730     

           800       810       820       830       840       850   
pF1KA2 IPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQA
       :::::::::::::.::.::::::::::.:::::::::::::.::::::::.::::. :::
NP_005 IPKGFMDGKQACERMIRALELDPNLYRIGQSKIFFRAGVLAHLEEERDLKITDIIIFFQA
         740       750       760       770       780       790     

           860       870       880       890       900       910   
pF1KA2 AARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQ
       . ::::::.:: :.::: :::.:.:::::::::::::::::.:::::::::::::.: ::
NP_005 VCRGYLARKAFAKKQQQLSALKVLQRNCAAYLKLRHWQWWRVFTKVKPLLQVTRQEEELQ
         800       810       820       830       840       850     

           920       930       940       950       960       970   
pF1KA2 ARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAA
       :. .:: ::.: : .   :. :.. .  :: ::.  :::::.::.:: ::::: :.::::
NP_005 AKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAA
         860       870       880       890       900       910     

           980       990      1000      1010      1020      1030   
pF1KA2 RKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVT
       .::::: .. .::.:: :::: .. .:.:::..: :::.:: .:. ::::::::::::::
NP_005 KKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVT
         920       930       940       950       960       970     

          1040      1050      1060      1070      1080      1090   
pF1KA2 TEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEAT
       .:::.::.::..:::::::::. ::.::.:::.:: ::: ::::::.:.: :.: : :. 
NP_005 AEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVM
         980       990      1000      1010      1020      1030     

          1100      1110      1120      1130      1140      1150   
pF1KA2 IADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAA
       :.:.:.::.:::: :::::: ::.::::...::.:..: : . .::. ::..::::::.:
NP_005 ISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGA
        1040      1050      1060      1070      1080      1090     

          1160      1170      1180      1190      1200      1210   
pF1KA2 LARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGEL
       :::..::   . . :: .:: :: .:: :::.:::...:.:::::.:::.::::::. ::
NP_005 LARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTEL
        1100      1110      1120      1130      1140      1150     

          1220      1230      1240      1250      1260      1270   
pF1KA2 EDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQA
       :::::.: ::::::.::::::.::::.:::::. ::: .:..::::. :: ::.::::::
NP_005 EDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQA
        1160      1170      1180      1190      1200      1210     

          1280      1290      1300      1310      1320      1330   
pF1KA2 RRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERAR
       .: :.  ::.. .::.. .::  :.. :: .. :.:..:..:. :.::.......:.: :
NP_005 KRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLR
        1220      1230      1240      1250      1260      1270     

          1340      1350      1360      1370      1380      1390   
pF1KA2 AEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALG
       .: ::: .. : ::.:::  :.:::.: :...:. .: :.::.:.::::::::: :: :.
NP_005 VELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLS
        1280      1290      1300      1310      1320      1330     

          1400      1410      1420      1430      1440      1450   
pF1KA2 SRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARR
       ::.: .: :  .:.:: :::  ::.   ... . :.::.. ... ... :..:. :::..
NP_005 SRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKK
        1340      1350      1360      1370      1380      1390     

          1460      1470      1480      1490      1500      1510   
pF1KA2 RAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQ
       .  ..::::.::: ::. . :.::. . :::::::: :.::..:::..:.:::::.::::
NP_005 KLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQ
        1400      1410      1420      1430      1440      1450     

          1520      1530      1540      1550      1560      1570   
pF1KA2 LLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEA
       ::::::.   : .:::.:::::.::.:..::::.:::::  ::.::.::::. :::..: 
NP_005 LLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMED
        1460      1470      1480      1490      1500      1510     

          1580      1590      1600      1610      1620      1630   
pF1KA2 LLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQ
       :.::::::::.:::::.. :. :: ....:.:. :::::: :.:::::::::..::.:.:
NP_005 LMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQ
        1520      1530      1540      1550      1560      1570     

          1640      1650      1660      1670      1680      1690   
pF1KA2 HERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMAS
        ::::: ::: .::..: : ::.:. :.: ..:::::.::::..::.: .:..:.::. .
NP_005 FERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEA
        1580      1590      1600      1610      1620      1630     

          1700      1710      1720      1730      1740      1750   
pF1KA2 AGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEE
       :.....:..:::::.:::::.  ::.::.:.::.:::.:..::::.::.::::.:.::::
NP_005 ANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEE
        1640      1650      1660      1670      1680      1690     

          1760      1770      1780      1790      1800      1810   
pF1KA2 LAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELL
       ::.:.::::.:.:.:::.:::..:.  .:.:.:.:::.::.:..:::::::::::: :::
NP_005 LASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELL
        1700      1710      1720      1730      1740      1750     

          1820      1830      1840      1850      1860      1870   
pF1KA2 NDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMT
       :::.::  :::..:..::.:::: . :....::::::: .::...: : ....... : :
NP_005 NDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKAT
        1760      1770      1780      1790      1800      1810     

          1880      1890      1900      1910      1920      1930   
pF1KA2 IAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKG
       :.:::.:..: :::::::..::  ..:::::.::.:::. .:::.::: ::: ..:.::.
NP_005 ISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKA
        1820      1830      1840      1850      1860      1870     

          1940      1950      1960      1970      1980       1990  
pF1KA2 NLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRG-PLT
       : :.::::::::::::::.::.:.::.:::::.:.::. :...:::.::.:::::: :..
NP_005 NARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLRRGGPIS
        1880      1890      1900      1910      1920      1930     

            2000         2010      2020      2030      
pF1KA2 FTT-RTVRQVFRLEEGVA---SDEEAEEAQPGSGPSPEPEGSPPAHPQ
       :.. :. :. ..:: :..   ::...:     :  :   : .::    
NP_005 FSSSRSGRRQLHLE-GASLELSDDDTE-----SKTSDVNETQPPQSE 
        1940       1950      1960           1970       




2036 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Wed Nov  2 22:28:32 2016 done: Wed Nov  2 22:28:36 2016
 Total Scan time: 22.040 Total Display time:  1.550

Function used was FASTA [36.3.4 Apr, 2011]
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