Result of FASTA (omim) for pF1KA1682
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KA1682, 747 aa
  1>>>pF1KA1682 747 - 747 aa - 747 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.6892+/-0.000406; mu= 18.2391+/- 0.025
 mean_var=75.8038+/-15.059, 0's: 0 Z-trim(113.0): 106  B-trim: 0 in 0/51
 Lambda= 0.147309
 statistics sampled from 22027 (22133) to 22027 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.63), E-opt: 0.2 (0.26), width:  16
 Scan time: 11.340

The best scores are:                                      opt bits E(85289)
NP_001035536 (OMIM: 606501) myotubularin-related p ( 747) 5097 1093.2       0
XP_005248370 (OMIM: 606501) PREDICTED: myotubulari ( 767) 3831 824.2       0
XP_016865084 (OMIM: 606501) PREDICTED: myotubulari ( 544) 3746 806.0       0
XP_016865083 (OMIM: 606501) PREDICTED: myotubulari ( 544) 3746 806.0       0
XP_016865082 (OMIM: 606501) PREDICTED: myotubulari ( 544) 3746 806.0       0
XP_011512360 (OMIM: 606501) PREDICTED: myotubulari ( 779) 3493 752.3 1.7e-216
NP_001281272 (OMIM: 606501) myotubularin-related p ( 693) 3459 745.1 2.2e-214
NP_001281273 (OMIM: 606501) myotubularin-related p ( 637) 3063 660.9 4.5e-189
XP_016865078 (OMIM: 606501) PREDICTED: myotubulari ( 691) 3063 660.9 4.8e-189
XP_011512361 (OMIM: 606501) PREDICTED: myotubulari ( 743) 2728 589.8 1.4e-167
XP_016865081 (OMIM: 606501) PREDICTED: myotubulari ( 564) 2480 537.0 8.1e-152
XP_016865079 (OMIM: 606501) PREDICTED: myotubulari ( 596) 2227 483.2 1.3e-135
XP_016865080 (OMIM: 606501) PREDICTED: myotubulari ( 596) 2227 483.2 1.3e-135
XP_011512359 (OMIM: 606501) PREDICTED: myotubulari ( 799) 2227 483.3 1.7e-135
XP_016865085 (OMIM: 606501) PREDICTED: myotubulari ( 488) 1712 373.7 9.7e-103
XP_011512362 (OMIM: 606501) PREDICTED: myotubulari ( 669) 1597 349.4 2.9e-95
XP_011542133 (OMIM: 606260) PREDICTED: myotubulari ( 353)  426 100.4 1.4e-20
XP_011542132 (OMIM: 606260) PREDICTED: myotubulari ( 442)  426 100.4 1.7e-20
NP_056273 (OMIM: 606260) myotubularin-related prot ( 549)  426 100.5   2e-20
XP_016885412 (OMIM: 300171) PREDICTED: myotubulari ( 552)  392 93.2   3e-18
NP_001230500 (OMIM: 601382,603557) myotubularin-re ( 571)  392 93.2 3.1e-18
XP_016885410 (OMIM: 300171) PREDICTED: myotubulari ( 571)  392 93.2 3.1e-18
XP_005274432 (OMIM: 601382,603557) PREDICTED: myot ( 571)  392 93.2 3.1e-18
XP_011529511 (OMIM: 300171) PREDICTED: myotubulari ( 571)  392 93.2 3.1e-18
XP_006718999 (OMIM: 601382,603557) PREDICTED: myot ( 571)  392 93.2 3.1e-18
XP_016874007 (OMIM: 601382,603557) PREDICTED: myot ( 571)  392 93.2 3.1e-18
XP_006718997 (OMIM: 601382,603557) PREDICTED: myot ( 571)  392 93.2 3.1e-18
XP_016874006 (OMIM: 601382,603557) PREDICTED: myot ( 571)  392 93.2 3.1e-18
XP_016885411 (OMIM: 300171) PREDICTED: myotubulari ( 571)  392 93.2 3.1e-18
NP_958435 (OMIM: 601382,603557) myotubularin-relat ( 571)  392 93.2 3.1e-18
XP_005274431 (OMIM: 601382,603557) PREDICTED: myot ( 571)  392 93.2 3.1e-18
XP_006718998 (OMIM: 601382,603557) PREDICTED: myot ( 571)  392 93.2 3.1e-18
NP_958438 (OMIM: 601382,603557) myotubularin-relat ( 571)  392 93.2 3.1e-18
XP_011541361 (OMIM: 601382,603557) PREDICTED: myot ( 596)  392 93.2 3.2e-18
XP_011541360 (OMIM: 601382,603557) PREDICTED: myot ( 596)  392 93.2 3.2e-18
NP_057240 (OMIM: 601382,603557) myotubularin-relat ( 643)  392 93.3 3.4e-18
XP_006724918 (OMIM: 300171) PREDICTED: myotubulari ( 665)  392 93.3 3.5e-18
NP_003819 (OMIM: 300171) myotubularin-related prot ( 665)  392 93.3 3.5e-18
NP_001293073 (OMIM: 300171) myotubularin-related p ( 673)  392 93.3 3.6e-18
XP_005274823 (OMIM: 300171) PREDICTED: myotubulari ( 682)  392 93.3 3.6e-18
XP_005274824 (OMIM: 300171) PREDICTED: myotubulari ( 682)  392 93.3 3.6e-18
XP_005274822 (OMIM: 300171) PREDICTED: myotubulari ( 699)  392 93.3 3.7e-18
XP_016885409 (OMIM: 300171) PREDICTED: myotubulari ( 602)  391 93.0 3.8e-18
XP_016885040 (OMIM: 300415,310400) PREDICTED: myot ( 355)  387 92.1 4.4e-18
XP_016885039 (OMIM: 300415,310400) PREDICTED: myot ( 566)  387 92.2 6.5e-18
XP_016885038 (OMIM: 300415,310400) PREDICTED: myot ( 602)  387 92.2 6.8e-18
XP_011529475 (OMIM: 300415,310400) PREDICTED: myot ( 603)  387 92.2 6.8e-18
NP_000243 (OMIM: 300415,310400) myotubularin [Homo ( 603)  387 92.2 6.8e-18
XP_005274744 (OMIM: 300415,310400) PREDICTED: myot ( 603)  387 92.2 6.8e-18
XP_016885036 (OMIM: 300415,310400) PREDICTED: myot ( 617)  387 92.2 6.9e-18


>>NP_001035536 (OMIM: 606501) myotubularin-related prote  (747 aa)
 initn: 5097 init1: 5097 opt: 5097  Z-score: 5850.6  bits: 1093.2 E(85289):    0
Smith-Waterman score: 5097; 100.0% identity (100.0% similar) in 747 aa overlap (1-747:1-747)

               10        20        30        40        50        60
pF1KA1 MLGKGVVGGGGGTKAPKPSFVSYVRPEEIHTNEKEVTEKEVTLHLLPGEQLLCEASTVLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLGKGVVGGGGGTKAPKPSFVSYVRPEEIHTNEKEVTEKEVTLHLLPGEQLLCEASTVLK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA1 YVQEDSCQHGVYGRLVCTDFKIAFLGDDESALDNDETQFKNKVIGENDITLHCVDQIYGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YVQEDSCQHGVYGRLVCTDFKIAFLGDDESALDNDETQFKNKVIGENDITLHCVDQIYGV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA1 FDEKKKTLFGQLKKYPEKLIIHCKDLRVFQFCLRYTKEEEVKRIVSGIIHHTQAPKLLKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FDEKKKTLFGQLKKYPEKLIIHCKDLRVFQFCLRYTKEEEVKRIVSGIIHHTQAPKLLKR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA1 LFLFSYATAAQNNTVTDPKNHTVMFDTLKDWCWELERTKGNMKYKAVSVNEGYKVCERLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFLFSYATAAQNNTVTDPKNHTVMFDTLKDWCWELERTKGNMKYKAVSVNEGYKVCERLP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA1 AYFVVPTPLPEENVQRFQGHGIPIWCWSCHNGSALLKMSALPKEQDDGILQIQKSFLDGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AYFVVPTPLPEENVQRFQGHGIPIWCWSCHNGSALLKMSALPKEQDDGILQIQKSFLDGI
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA1 YKTIHRPPYEIVKTEDLSSNFLSLQEIQTAYSKFKQLFLIDNSTEFWDTDIKWFSLLESS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YKTIHRPPYEIVKTEDLSSNFLSLQEIQTAYSKFKQLFLIDNSTEFWDTDIKWFSLLESS
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA1 SWLDIIRRCLKKAIEITECMEAQNMNVLLLEENASDLCCLISSLVQLMMDPHCRTRIGFQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SWLDIIRRCLKKAIEITECMEAQNMNVLLLEENASDLCCLISSLVQLMMDPHCRTRIGFQ
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA1 SLIQKEWVMGGHCFLDRCNHLRQNDKEEVPVFLLFLDCVWQLVHQHPPAFEFTETYLTVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLIQKEWVMGGHCFLDRCNHLRQNDKEEVPVFLLFLDCVWQLVHQHPPAFEFTETYLTVL
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA1 SDSLYIPIFSTFFFNSPHQKDTNMGREGQDTQSKPLNLLTVWDWSVQFEPKAQTLLKNPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SDSLYIPIFSTFFFNSPHQKDTNMGREGQDTQSKPLNLLTVWDWSVQFEPKAQTLLKNPL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA1 YVEKPKLDKGQRKGMRFKHQRQLSLPLTQSKSSPKRGFFREETDHLIKNLLGKRISKLIN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YVEKPKLDKGQRKGMRFKHQRQLSLPLTQSKSSPKRGFFREETDHLIKNLLGKRISKLIN
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA1 SSDELQDNFREFYDSWHSKSTDYHGLLLPHIEGPEIKVWAQRYLRWIPEAQILGGGQVAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSDELQDNFREFYDSWHSKSTDYHGLLLPHIEGPEIKVWAQRYLRWIPEAQILGGGQVAT
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA1 LSKLLEMMEEVQSLQEKIDERHHSQQAPQAEAPCLLRNSARLSSLFPFALLQRHSSKPVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSKLLEMMEEVQSLQEKIDERHHSQQAPQAEAPCLLRNSARLSSLFPFALLQRHSSKPVL
              670       680       690       700       710       720

              730       740       
pF1KA1 PTSGWKALGDEDDLAKREDEFVDLGDV
       :::::::::::::::::::::::::::
NP_001 PTSGWKALGDEDDLAKREDEFVDLGDV
              730       740       

>>XP_005248370 (OMIM: 606501) PREDICTED: myotubularin-re  (767 aa)
 initn: 5083 init1: 3828 opt: 3831  Z-score: 4396.3  bits: 824.2 E(85289):    0
Smith-Waterman score: 5047; 97.4% identity (97.4% similar) in 767 aa overlap (1-747:1-767)

               10        20        30        40        50        60
pF1KA1 MLGKGVVGGGGGTKAPKPSFVSYVRPEEIHTNEKEVTEKEVTLHLLPGEQLLCEASTVLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MLGKGVVGGGGGTKAPKPSFVSYVRPEEIHTNEKEVTEKEVTLHLLPGEQLLCEASTVLK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA1 YVQEDSCQHGVYGRLVCTDFKIAFLGDDESALDNDETQFKNKVIGENDITLHCVDQIYGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YVQEDSCQHGVYGRLVCTDFKIAFLGDDESALDNDETQFKNKVIGENDITLHCVDQIYGV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA1 FDEKKKTLFGQLKKYPEKLIIHCKDLRVFQFCLRYTKEEEVKRIVSGIIHHTQAPKLLKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FDEKKKTLFGQLKKYPEKLIIHCKDLRVFQFCLRYTKEEEVKRIVSGIIHHTQAPKLLKR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA1 LFLFSYATAAQNNTVTDPKNHTVMFDTLKDWCWELERTKGNMKYKAVSVNEGYKVCERLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LFLFSYATAAQNNTVTDPKNHTVMFDTLKDWCWELERTKGNMKYKAVSVNEGYKVCERLP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA1 AYFVVPTPLPEENVQRFQGHGIPIWCWSCHNGSALLKMSALPKEQDDGILQIQKSFLDGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AYFVVPTPLPEENVQRFQGHGIPIWCWSCHNGSALLKMSALPKEQDDGILQIQKSFLDGI
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA1 YKTIHRPPYEIVKTEDLSSNFLSLQEIQTAYSKFKQLFLIDNSTEFWDTDIKWFSLLESS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YKTIHRPPYEIVKTEDLSSNFLSLQEIQTAYSKFKQLFLIDNSTEFWDTDIKWFSLLESS
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA1 SWLDIIRRCLKKAIEITECMEAQNMNVLLLEENASDLCCLISSLVQLMMDPHCRTRIGFQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SWLDIIRRCLKKAIEITECMEAQNMNVLLLEENASDLCCLISSLVQLMMDPHCRTRIGFQ
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA1 SLIQKEWVMGGHCFLDRCNHLRQNDKEEVPVFLLFLDCVWQLVHQHPPAFEFTETYLTVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLIQKEWVMGGHCFLDRCNHLRQNDKEEVPVFLLFLDCVWQLVHQHPPAFEFTETYLTVL
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA1 SDSLYIPIFSTFFFNSPHQKDTNMGREGQDTQSKPLNLLTVWDWSVQFEPKAQTLLKNPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SDSLYIPIFSTFFFNSPHQKDTNMGREGQDTQSKPLNLLTVWDWSVQFEPKAQTLLKNPL
              490       500       510       520       530       540

              550                           560       570       580
pF1KA1 YVEKPKLDKGQRKGMRFK--------------------HQRQLSLPLTQSKSSPKRGFFR
       ::::::::::::::::::                    ::::::::::::::::::::::
XP_005 YVEKPKLDKGQRKGMRFKLCLQAQNFSPTESTKERAVMHQRQLSLPLTQSKSSPKRGFFR
              550       560       570       580       590       600

              590       600       610       620       630       640
pF1KA1 EETDHLIKNLLGKRISKLINSSDELQDNFREFYDSWHSKSTDYHGLLLPHIEGPEIKVWA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EETDHLIKNLLGKRISKLINSSDELQDNFREFYDSWHSKSTDYHGLLLPHIEGPEIKVWA
              610       620       630       640       650       660

              650       660       670       680       690       700
pF1KA1 QRYLRWIPEAQILGGGQVATLSKLLEMMEEVQSLQEKIDERHHSQQAPQAEAPCLLRNSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QRYLRWIPEAQILGGGQVATLSKLLEMMEEVQSLQEKIDERHHSQQAPQAEAPCLLRNSA
              670       680       690       700       710       720

              710       720       730       740       
pF1KA1 RLSSLFPFALLQRHSSKPVLPTSGWKALGDEDDLAKREDEFVDLGDV
       :::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RLSSLFPFALLQRHSSKPVLPTSGWKALGDEDDLAKREDEFVDLGDV
              730       740       750       760       

>>XP_016865084 (OMIM: 606501) PREDICTED: myotubularin-re  (544 aa)
 initn: 3746 init1: 3746 opt: 3746  Z-score: 4300.9  bits: 806.0 E(85289):    0
Smith-Waterman score: 3746; 100.0% identity (100.0% similar) in 544 aa overlap (204-747:1-544)

           180       190       200       210       220       230   
pF1KA1 APKLLKRLFLFSYATAAQNNTVTDPKNHTVMFDTLKDWCWELERTKGNMKYKAVSVNEGY
                                     ::::::::::::::::::::::::::::::
XP_016                               MFDTLKDWCWELERTKGNMKYKAVSVNEGY
                                             10        20        30

           240       250       260       270       280       290   
pF1KA1 KVCERLPAYFVVPTPLPEENVQRFQGHGIPIWCWSCHNGSALLKMSALPKEQDDGILQIQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVCERLPAYFVVPTPLPEENVQRFQGHGIPIWCWSCHNGSALLKMSALPKEQDDGILQIQ
               40        50        60        70        80        90

           300       310       320       330       340       350   
pF1KA1 KSFLDGIYKTIHRPPYEIVKTEDLSSNFLSLQEIQTAYSKFKQLFLIDNSTEFWDTDIKW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSFLDGIYKTIHRPPYEIVKTEDLSSNFLSLQEIQTAYSKFKQLFLIDNSTEFWDTDIKW
              100       110       120       130       140       150

           360       370       380       390       400       410   
pF1KA1 FSLLESSSWLDIIRRCLKKAIEITECMEAQNMNVLLLEENASDLCCLISSLVQLMMDPHC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSLLESSSWLDIIRRCLKKAIEITECMEAQNMNVLLLEENASDLCCLISSLVQLMMDPHC
              160       170       180       190       200       210

           420       430       440       450       460       470   
pF1KA1 RTRIGFQSLIQKEWVMGGHCFLDRCNHLRQNDKEEVPVFLLFLDCVWQLVHQHPPAFEFT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTRIGFQSLIQKEWVMGGHCFLDRCNHLRQNDKEEVPVFLLFLDCVWQLVHQHPPAFEFT
              220       230       240       250       260       270

           480       490       500       510       520       530   
pF1KA1 ETYLTVLSDSLYIPIFSTFFFNSPHQKDTNMGREGQDTQSKPLNLLTVWDWSVQFEPKAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETYLTVLSDSLYIPIFSTFFFNSPHQKDTNMGREGQDTQSKPLNLLTVWDWSVQFEPKAQ
              280       290       300       310       320       330

           540       550       560       570       580       590   
pF1KA1 TLLKNPLYVEKPKLDKGQRKGMRFKHQRQLSLPLTQSKSSPKRGFFREETDHLIKNLLGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLLKNPLYVEKPKLDKGQRKGMRFKHQRQLSLPLTQSKSSPKRGFFREETDHLIKNLLGK
              340       350       360       370       380       390

           600       610       620       630       640       650   
pF1KA1 RISKLINSSDELQDNFREFYDSWHSKSTDYHGLLLPHIEGPEIKVWAQRYLRWIPEAQIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RISKLINSSDELQDNFREFYDSWHSKSTDYHGLLLPHIEGPEIKVWAQRYLRWIPEAQIL
              400       410       420       430       440       450

           660       670       680       690       700       710   
pF1KA1 GGGQVATLSKLLEMMEEVQSLQEKIDERHHSQQAPQAEAPCLLRNSARLSSLFPFALLQR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGGQVATLSKLLEMMEEVQSLQEKIDERHHSQQAPQAEAPCLLRNSARLSSLFPFALLQR
              460       470       480       490       500       510

           720       730       740       
pF1KA1 HSSKPVLPTSGWKALGDEDDLAKREDEFVDLGDV
       ::::::::::::::::::::::::::::::::::
XP_016 HSSKPVLPTSGWKALGDEDDLAKREDEFVDLGDV
              520       530       540    

>>XP_016865083 (OMIM: 606501) PREDICTED: myotubularin-re  (544 aa)
 initn: 3746 init1: 3746 opt: 3746  Z-score: 4300.9  bits: 806.0 E(85289):    0
Smith-Waterman score: 3746; 100.0% identity (100.0% similar) in 544 aa overlap (204-747:1-544)

           180       190       200       210       220       230   
pF1KA1 APKLLKRLFLFSYATAAQNNTVTDPKNHTVMFDTLKDWCWELERTKGNMKYKAVSVNEGY
                                     ::::::::::::::::::::::::::::::
XP_016                               MFDTLKDWCWELERTKGNMKYKAVSVNEGY
                                             10        20        30

           240       250       260       270       280       290   
pF1KA1 KVCERLPAYFVVPTPLPEENVQRFQGHGIPIWCWSCHNGSALLKMSALPKEQDDGILQIQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVCERLPAYFVVPTPLPEENVQRFQGHGIPIWCWSCHNGSALLKMSALPKEQDDGILQIQ
               40        50        60        70        80        90

           300       310       320       330       340       350   
pF1KA1 KSFLDGIYKTIHRPPYEIVKTEDLSSNFLSLQEIQTAYSKFKQLFLIDNSTEFWDTDIKW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSFLDGIYKTIHRPPYEIVKTEDLSSNFLSLQEIQTAYSKFKQLFLIDNSTEFWDTDIKW
              100       110       120       130       140       150

           360       370       380       390       400       410   
pF1KA1 FSLLESSSWLDIIRRCLKKAIEITECMEAQNMNVLLLEENASDLCCLISSLVQLMMDPHC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSLLESSSWLDIIRRCLKKAIEITECMEAQNMNVLLLEENASDLCCLISSLVQLMMDPHC
              160       170       180       190       200       210

           420       430       440       450       460       470   
pF1KA1 RTRIGFQSLIQKEWVMGGHCFLDRCNHLRQNDKEEVPVFLLFLDCVWQLVHQHPPAFEFT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTRIGFQSLIQKEWVMGGHCFLDRCNHLRQNDKEEVPVFLLFLDCVWQLVHQHPPAFEFT
              220       230       240       250       260       270

           480       490       500       510       520       530   
pF1KA1 ETYLTVLSDSLYIPIFSTFFFNSPHQKDTNMGREGQDTQSKPLNLLTVWDWSVQFEPKAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETYLTVLSDSLYIPIFSTFFFNSPHQKDTNMGREGQDTQSKPLNLLTVWDWSVQFEPKAQ
              280       290       300       310       320       330

           540       550       560       570       580       590   
pF1KA1 TLLKNPLYVEKPKLDKGQRKGMRFKHQRQLSLPLTQSKSSPKRGFFREETDHLIKNLLGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLLKNPLYVEKPKLDKGQRKGMRFKHQRQLSLPLTQSKSSPKRGFFREETDHLIKNLLGK
              340       350       360       370       380       390

           600       610       620       630       640       650   
pF1KA1 RISKLINSSDELQDNFREFYDSWHSKSTDYHGLLLPHIEGPEIKVWAQRYLRWIPEAQIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RISKLINSSDELQDNFREFYDSWHSKSTDYHGLLLPHIEGPEIKVWAQRYLRWIPEAQIL
              400       410       420       430       440       450

           660       670       680       690       700       710   
pF1KA1 GGGQVATLSKLLEMMEEVQSLQEKIDERHHSQQAPQAEAPCLLRNSARLSSLFPFALLQR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGGQVATLSKLLEMMEEVQSLQEKIDERHHSQQAPQAEAPCLLRNSARLSSLFPFALLQR
              460       470       480       490       500       510

           720       730       740       
pF1KA1 HSSKPVLPTSGWKALGDEDDLAKREDEFVDLGDV
       ::::::::::::::::::::::::::::::::::
XP_016 HSSKPVLPTSGWKALGDEDDLAKREDEFVDLGDV
              520       530       540    

>>XP_016865082 (OMIM: 606501) PREDICTED: myotubularin-re  (544 aa)
 initn: 3746 init1: 3746 opt: 3746  Z-score: 4300.9  bits: 806.0 E(85289):    0
Smith-Waterman score: 3746; 100.0% identity (100.0% similar) in 544 aa overlap (204-747:1-544)

           180       190       200       210       220       230   
pF1KA1 APKLLKRLFLFSYATAAQNNTVTDPKNHTVMFDTLKDWCWELERTKGNMKYKAVSVNEGY
                                     ::::::::::::::::::::::::::::::
XP_016                               MFDTLKDWCWELERTKGNMKYKAVSVNEGY
                                             10        20        30

           240       250       260       270       280       290   
pF1KA1 KVCERLPAYFVVPTPLPEENVQRFQGHGIPIWCWSCHNGSALLKMSALPKEQDDGILQIQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVCERLPAYFVVPTPLPEENVQRFQGHGIPIWCWSCHNGSALLKMSALPKEQDDGILQIQ
               40        50        60        70        80        90

           300       310       320       330       340       350   
pF1KA1 KSFLDGIYKTIHRPPYEIVKTEDLSSNFLSLQEIQTAYSKFKQLFLIDNSTEFWDTDIKW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSFLDGIYKTIHRPPYEIVKTEDLSSNFLSLQEIQTAYSKFKQLFLIDNSTEFWDTDIKW
              100       110       120       130       140       150

           360       370       380       390       400       410   
pF1KA1 FSLLESSSWLDIIRRCLKKAIEITECMEAQNMNVLLLEENASDLCCLISSLVQLMMDPHC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSLLESSSWLDIIRRCLKKAIEITECMEAQNMNVLLLEENASDLCCLISSLVQLMMDPHC
              160       170       180       190       200       210

           420       430       440       450       460       470   
pF1KA1 RTRIGFQSLIQKEWVMGGHCFLDRCNHLRQNDKEEVPVFLLFLDCVWQLVHQHPPAFEFT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTRIGFQSLIQKEWVMGGHCFLDRCNHLRQNDKEEVPVFLLFLDCVWQLVHQHPPAFEFT
              220       230       240       250       260       270

           480       490       500       510       520       530   
pF1KA1 ETYLTVLSDSLYIPIFSTFFFNSPHQKDTNMGREGQDTQSKPLNLLTVWDWSVQFEPKAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETYLTVLSDSLYIPIFSTFFFNSPHQKDTNMGREGQDTQSKPLNLLTVWDWSVQFEPKAQ
              280       290       300       310       320       330

           540       550       560       570       580       590   
pF1KA1 TLLKNPLYVEKPKLDKGQRKGMRFKHQRQLSLPLTQSKSSPKRGFFREETDHLIKNLLGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLLKNPLYVEKPKLDKGQRKGMRFKHQRQLSLPLTQSKSSPKRGFFREETDHLIKNLLGK
              340       350       360       370       380       390

           600       610       620       630       640       650   
pF1KA1 RISKLINSSDELQDNFREFYDSWHSKSTDYHGLLLPHIEGPEIKVWAQRYLRWIPEAQIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RISKLINSSDELQDNFREFYDSWHSKSTDYHGLLLPHIEGPEIKVWAQRYLRWIPEAQIL
              400       410       420       430       440       450

           660       670       680       690       700       710   
pF1KA1 GGGQVATLSKLLEMMEEVQSLQEKIDERHHSQQAPQAEAPCLLRNSARLSSLFPFALLQR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGGQVATLSKLLEMMEEVQSLQEKIDERHHSQQAPQAEAPCLLRNSARLSSLFPFALLQR
              460       470       480       490       500       510

           720       730       740       
pF1KA1 HSSKPVLPTSGWKALGDEDDLAKREDEFVDLGDV
       ::::::::::::::::::::::::::::::::::
XP_016 HSSKPVLPTSGWKALGDEDDLAKREDEFVDLGDV
              520       530       540    

>>XP_011512360 (OMIM: 606501) PREDICTED: myotubularin-re  (779 aa)
 initn: 5076 init1: 3493 opt: 3493  Z-score: 4008.0  bits: 752.3 E(85289): 1.7e-216
Smith-Waterman score: 5015; 95.8% identity (95.8% similar) in 779 aa overlap (1-747:1-779)

               10        20        30        40        50        60
pF1KA1 MLGKGVVGGGGGTKAPKPSFVSYVRPEEIHTNEKEVTEKEVTLHLLPGEQLLCEASTVLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLGKGVVGGGGGTKAPKPSFVSYVRPEEIHTNEKEVTEKEVTLHLLPGEQLLCEASTVLK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA1 YVQEDSCQHGVYGRLVCTDFKIAFLGDDESALDNDETQFKNKVIGENDITLHCVDQIYGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YVQEDSCQHGVYGRLVCTDFKIAFLGDDESALDNDETQFKNKVIGENDITLHCVDQIYGV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA1 FDEKKKTLFGQLKKYPEKLIIHCKDLRVFQFCLRYTKEEEVKRIVSGIIHHTQAPKLLKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FDEKKKTLFGQLKKYPEKLIIHCKDLRVFQFCLRYTKEEEVKRIVSGIIHHTQAPKLLKR
              130       140       150       160       170       180

              190       200       210       220       230          
pF1KA1 LFLFSYATAAQNNTVTDPKNHTVMFDTLKDWCWELERTKGNMKYKAVSVNEGYKVCER--
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::   
XP_011 LFLFSYATAAQNNTVTDPKNHTVMFDTLKDWCWELERTKGNMKYKAVSVNEGYKVCESVT
              190       200       210       220       230       240

                                    240       250       260        
pF1KA1 ------------------------------LPAYFVVPTPLPEENVQRFQGHGIPIWCWS
                                     ::::::::::::::::::::::::::::::
XP_011 RWLASKRSSINRRQKEKPHLYLEGDLRQFGLPAYFVVPTPLPEENVQRFQGHGIPIWCWS
              250       260       270       280       290       300

      270       280       290       300       310       320        
pF1KA1 CHNGSALLKMSALPKEQDDGILQIQKSFLDGIYKTIHRPPYEIVKTEDLSSNFLSLQEIQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CHNGSALLKMSALPKEQDDGILQIQKSFLDGIYKTIHRPPYEIVKTEDLSSNFLSLQEIQ
              310       320       330       340       350       360

      330       340       350       360       370       380        
pF1KA1 TAYSKFKQLFLIDNSTEFWDTDIKWFSLLESSSWLDIIRRCLKKAIEITECMEAQNMNVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TAYSKFKQLFLIDNSTEFWDTDIKWFSLLESSSWLDIIRRCLKKAIEITECMEAQNMNVL
              370       380       390       400       410       420

      390       400       410       420       430       440        
pF1KA1 LLEENASDLCCLISSLVQLMMDPHCRTRIGFQSLIQKEWVMGGHCFLDRCNHLRQNDKEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLEENASDLCCLISSLVQLMMDPHCRTRIGFQSLIQKEWVMGGHCFLDRCNHLRQNDKEE
              430       440       450       460       470       480

      450       460       470       480       490       500        
pF1KA1 VPVFLLFLDCVWQLVHQHPPAFEFTETYLTVLSDSLYIPIFSTFFFNSPHQKDTNMGREG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPVFLLFLDCVWQLVHQHPPAFEFTETYLTVLSDSLYIPIFSTFFFNSPHQKDTNMGREG
              490       500       510       520       530       540

      510       520       530       540       550       560        
pF1KA1 QDTQSKPLNLLTVWDWSVQFEPKAQTLLKNPLYVEKPKLDKGQRKGMRFKHQRQLSLPLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QDTQSKPLNLLTVWDWSVQFEPKAQTLLKNPLYVEKPKLDKGQRKGMRFKHQRQLSLPLT
              550       560       570       580       590       600

      570       580       590       600       610       620        
pF1KA1 QSKSSPKRGFFREETDHLIKNLLGKRISKLINSSDELQDNFREFYDSWHSKSTDYHGLLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QSKSSPKRGFFREETDHLIKNLLGKRISKLINSSDELQDNFREFYDSWHSKSTDYHGLLL
              610       620       630       640       650       660

      630       640       650       660       670       680        
pF1KA1 PHIEGPEIKVWAQRYLRWIPEAQILGGGQVATLSKLLEMMEEVQSLQEKIDERHHSQQAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PHIEGPEIKVWAQRYLRWIPEAQILGGGQVATLSKLLEMMEEVQSLQEKIDERHHSQQAP
              670       680       690       700       710       720

      690       700       710       720       730       740       
pF1KA1 QAEAPCLLRNSARLSSLFPFALLQRHSSKPVLPTSGWKALGDEDDLAKREDEFVDLGDV
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QAEAPCLLRNSARLSSLFPFALLQRHSSKPVLPTSGWKALGDEDDLAKREDEFVDLGDV
              730       740       750       760       770         

>>NP_001281272 (OMIM: 606501) myotubularin-related prote  (693 aa)
 initn: 4710 init1: 3455 opt: 3459  Z-score: 3969.7  bits: 745.1 E(85289): 2.2e-214
Smith-Waterman score: 4606; 92.8% identity (92.8% similar) in 747 aa overlap (1-747:1-693)

               10        20        30        40        50        60
pF1KA1 MLGKGVVGGGGGTKAPKPSFVSYVRPEEIHTNEKEVTEKEVTLHLLPGEQLLCEASTVLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLGKGVVGGGGGTKAPKPSFVSYVRPEEIHTNEKEVTEKEVTLHLLPGEQLLCEASTVLK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA1 YVQEDSCQHGVYGRLVCTDFKIAFLGDDESALDNDETQFKNKVIGENDITLHCVDQIYGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YVQEDSCQHGVYGRLVCTDFKIAFLGDDESALDNDETQFKNKVIGENDITLHCVDQIYGV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA1 FDEKKKTLFGQLKKYPEKLIIHCKDLRVFQFCLRYTKEEEVKRIVSGIIHHTQAPKLLKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FDEKKKTLFGQLKKYPEKLIIHCKDLRVFQFCLRYTKEEEVKRIVSGIIHHTQAPKLLKR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA1 LFLFSYATAAQNNTVTDPKNHTVMFDTLKDWCWELERTKGNMKYKAVSVNEGYKVCERLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFLFSYATAAQNNTVTDPKNHTVMFDTLKDWCWELERTKGNMKYKAVSVNEGYKVCERLP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA1 AYFVVPTPLPEENVQRFQGHGIPIWCWSCHNGSALLKMSALPKEQDDGILQIQKSFLDGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AYFVVPTPLPEENVQRFQGHGIPIWCWSCHNGSALLKMSALPKEQDDGILQIQKSFLDGI
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA1 YKTIHRPPYEIVKTEDLSSNFLSLQEIQTAYSKFKQLFLIDNSTEFWDTDIKWFSLLESS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YKTIHRPPYEIVKTEDLSSNFLSLQEIQTAYSKFKQLFLIDNSTEFWDTDIKWFSLLESS
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA1 SWLDIIRRCLKKAIEITECMEAQNMNVLLLEENASDLCCLISSLVQLMMDPHCRTRIGFQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SWLDIIRRCLKKAIEITECMEAQNMNVLLLEENASDLCCLISSLVQLMMDPHCRTRIGFQ
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA1 SLIQKEWVMGGHCFLDRCNHLRQNDKEEVPVFLLFLDCVWQLVHQHPPAFEFTETYLTVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLIQKEWVMGGHCFLDRCNHLRQNDKEEVPVFLLFLDCVWQLVHQHPPAFEFTETYLTVL
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA1 SDSLYIPIFSTFFFNSPHQKDTNMGREGQDTQSKPLNLLTVWDWSVQFEPKAQTLLKNPL
       ::::::::::::::::::::::::                                    
NP_001 SDSLYIPIFSTFFFNSPHQKDTNM------------------------------------
              490       500                                        

              550       560       570       580       590       600
pF1KA1 YVEKPKLDKGQRKGMRFKHQRQLSLPLTQSKSSPKRGFFREETDHLIKNLLGKRISKLIN
                         ::::::::::::::::::::::::::::::::::::::::::
NP_001 ------------------HQRQLSLPLTQSKSSPKRGFFREETDHLIKNLLGKRISKLIN
                            510       520       530       540      

              610       620       630       640       650       660
pF1KA1 SSDELQDNFREFYDSWHSKSTDYHGLLLPHIEGPEIKVWAQRYLRWIPEAQILGGGQVAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSDELQDNFREFYDSWHSKSTDYHGLLLPHIEGPEIKVWAQRYLRWIPEAQILGGGQVAT
        550       560       570       580       590       600      

              670       680       690       700       710       720
pF1KA1 LSKLLEMMEEVQSLQEKIDERHHSQQAPQAEAPCLLRNSARLSSLFPFALLQRHSSKPVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSKLLEMMEEVQSLQEKIDERHHSQQAPQAEAPCLLRNSARLSSLFPFALLQRHSSKPVL
        610       620       630       640       650       660      

              730       740       
pF1KA1 PTSGWKALGDEDDLAKREDEFVDLGDV
       :::::::::::::::::::::::::::
NP_001 PTSGWKALGDEDDLAKREDEFVDLGDV
        670       680       690   

>>NP_001281273 (OMIM: 606501) myotubularin-related prote  (637 aa)
 initn: 3063 init1: 3063 opt: 3063  Z-score: 3515.4  bits: 660.9 E(85289): 4.5e-189
Smith-Waterman score: 4102; 85.3% identity (85.3% similar) in 747 aa overlap (1-747:1-637)

               10        20        30        40        50        60
pF1KA1 MLGKGVVGGGGGTKAPKPSFVSYVRPEEIHTNEKEVTEKEVTLHLLPGEQLLCEASTVLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLGKGVVGGGGGTKAPKPSFVSYVRPEEIHTNEKEVTEKEVTLHLLPGEQLLCEASTVLK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA1 YVQEDSCQHGVYGRLVCTDFKIAFLGDDESALDNDETQFKNKVIGENDITLHCVDQIYGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YVQEDSCQHGVYGRLVCTDFKIAFLGDDESALDNDETQFKNKVIGENDITLHCVDQIYGV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA1 FDEKKKTLFGQLKKYPEKLIIHCKDLRVFQFCLRYTKEEEVKRIVSGIIHHTQAPKLLKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FDEKKKTLFGQLKKYPEKLIIHCKDLRVFQFCLRYTKEEEVKRIVSGIIHHTQAPKLLKR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA1 LFLFSYATAAQNNTVTDPKNHTVMFDTLKDWCWELERTKGNMKYKAVSVNEGYKVCERLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFLFSYATAAQNNTVTDPKNHTVMFDTLKDWCWELERTKGNMKYKAVSVNEGYKVCERLP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA1 AYFVVPTPLPEENVQRFQGHGIPIWCWSCHNGSALLKMSALPKEQDDGILQIQKSFLDGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AYFVVPTPLPEENVQRFQGHGIPIWCWSCHNGSALLKMSALPKEQDDGILQIQKSFLDGI
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA1 YKTIHRPPYEIVKTEDLSSNFLSLQEIQTAYSKFKQLFLIDNSTEFWDTDIKWFSLLESS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YKTIHRPPYEIVKTEDLSSNFLSLQEIQTAYSKFKQLFLIDNSTEFWDTDIKWFSLLESS
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA1 SWLDIIRRCLKKAIEITECMEAQNMNVLLLEENASDLCCLISSLVQLMMDPHCRTRIGFQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SWLDIIRRCLKKAIEITECMEAQNMNVLLLEENASDLCCLISSLVQLMMDPHCRTRIGFQ
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA1 SLIQKEWVMGGHCFLDRCNHLRQNDKEEVPVFLLFLDCVWQLVHQHPPAFEFTETYLTVL
       ::::::::::::::::::::::::::::                                
NP_001 SLIQKEWVMGGHCFLDRCNHLRQNDKEE--------------------------------
              430       440                                        

              490       500       510       520       530       540
pF1KA1 SDSLYIPIFSTFFFNSPHQKDTNMGREGQDTQSKPLNLLTVWDWSVQFEPKAQTLLKNPL
                                                                   
NP_001 ------------------------------------------------------------
                                                                   

              550       560       570       580       590       600
pF1KA1 YVEKPKLDKGQRKGMRFKHQRQLSLPLTQSKSSPKRGFFREETDHLIKNLLGKRISKLIN
                         ::::::::::::::::::::::::::::::::::::::::::
NP_001 ------------------HQRQLSLPLTQSKSSPKRGFFREETDHLIKNLLGKRISKLIN
                        450       460       470       480       490

              610       620       630       640       650       660
pF1KA1 SSDELQDNFREFYDSWHSKSTDYHGLLLPHIEGPEIKVWAQRYLRWIPEAQILGGGQVAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSDELQDNFREFYDSWHSKSTDYHGLLLPHIEGPEIKVWAQRYLRWIPEAQILGGGQVAT
              500       510       520       530       540       550

              670       680       690       700       710       720
pF1KA1 LSKLLEMMEEVQSLQEKIDERHHSQQAPQAEAPCLLRNSARLSSLFPFALLQRHSSKPVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSKLLEMMEEVQSLQEKIDERHHSQQAPQAEAPCLLRNSARLSSLFPFALLQRHSSKPVL
              560       570       580       590       600       610

              730       740       
pF1KA1 PTSGWKALGDEDDLAKREDEFVDLGDV
       :::::::::::::::::::::::::::
NP_001 PTSGWKALGDEDDLAKREDEFVDLGDV
              620       630       

>>XP_016865078 (OMIM: 606501) PREDICTED: myotubularin-re  (691 aa)
 initn: 3063 init1: 3063 opt: 3063  Z-score: 3514.9  bits: 660.9 E(85289): 4.8e-189
Smith-Waterman score: 4583; 92.5% identity (92.5% similar) in 747 aa overlap (1-747:1-691)

               10        20        30        40        50        60
pF1KA1 MLGKGVVGGGGGTKAPKPSFVSYVRPEEIHTNEKEVTEKEVTLHLLPGEQLLCEASTVLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLGKGVVGGGGGTKAPKPSFVSYVRPEEIHTNEKEVTEKEVTLHLLPGEQLLCEASTVLK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA1 YVQEDSCQHGVYGRLVCTDFKIAFLGDDESALDNDETQFKNKVIGENDITLHCVDQIYGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YVQEDSCQHGVYGRLVCTDFKIAFLGDDESALDNDETQFKNKVIGENDITLHCVDQIYGV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA1 FDEKKKTLFGQLKKYPEKLIIHCKDLRVFQFCLRYTKEEEVKRIVSGIIHHTQAPKLLKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FDEKKKTLFGQLKKYPEKLIIHCKDLRVFQFCLRYTKEEEVKRIVSGIIHHTQAPKLLKR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA1 LFLFSYATAAQNNTVTDPKNHTVMFDTLKDWCWELERTKGNMKYKAVSVNEGYKVCERLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFLFSYATAAQNNTVTDPKNHTVMFDTLKDWCWELERTKGNMKYKAVSVNEGYKVCERLP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA1 AYFVVPTPLPEENVQRFQGHGIPIWCWSCHNGSALLKMSALPKEQDDGILQIQKSFLDGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AYFVVPTPLPEENVQRFQGHGIPIWCWSCHNGSALLKMSALPKEQDDGILQIQKSFLDGI
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA1 YKTIHRPPYEIVKTEDLSSNFLSLQEIQTAYSKFKQLFLIDNSTEFWDTDIKWFSLLESS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YKTIHRPPYEIVKTEDLSSNFLSLQEIQTAYSKFKQLFLIDNSTEFWDTDIKWFSLLESS
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA1 SWLDIIRRCLKKAIEITECMEAQNMNVLLLEENASDLCCLISSLVQLMMDPHCRTRIGFQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SWLDIIRRCLKKAIEITECMEAQNMNVLLLEENASDLCCLISSLVQLMMDPHCRTRIGFQ
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA1 SLIQKEWVMGGHCFLDRCNHLRQNDKEEVPVFLLFLDCVWQLVHQHPPAFEFTETYLTVL
       ::::::::::::::::::::::::::::                                
XP_016 SLIQKEWVMGGHCFLDRCNHLRQNDKEE--------------------------------
              430       440                                        

              490       500       510       520       530       540
pF1KA1 SDSLYIPIFSTFFFNSPHQKDTNMGREGQDTQSKPLNLLTVWDWSVQFEPKAQTLLKNPL
                               ::::::::::::::::::::::::::::::::::::
XP_016 ------------------------GREGQDTQSKPLNLLTVWDWSVQFEPKAQTLLKNPL
                              450       460       470       480    

              550       560       570       580       590       600
pF1KA1 YVEKPKLDKGQRKGMRFKHQRQLSLPLTQSKSSPKRGFFREETDHLIKNLLGKRISKLIN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YVEKPKLDKGQRKGMRFKHQRQLSLPLTQSKSSPKRGFFREETDHLIKNLLGKRISKLIN
          490       500       510       520       530       540    

              610       620       630       640       650       660
pF1KA1 SSDELQDNFREFYDSWHSKSTDYHGLLLPHIEGPEIKVWAQRYLRWIPEAQILGGGQVAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSDELQDNFREFYDSWHSKSTDYHGLLLPHIEGPEIKVWAQRYLRWIPEAQILGGGQVAT
          550       560       570       580       590       600    

              670       680       690       700       710       720
pF1KA1 LSKLLEMMEEVQSLQEKIDERHHSQQAPQAEAPCLLRNSARLSSLFPFALLQRHSSKPVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSKLLEMMEEVQSLQEKIDERHHSQQAPQAEAPCLLRNSARLSSLFPFALLQRHSSKPVL
          610       620       630       640       650       660    

              730       740       
pF1KA1 PTSGWKALGDEDDLAKREDEFVDLGDV
       :::::::::::::::::::::::::::
XP_016 PTSGWKALGDEDDLAKREDEFVDLGDV
          670       680       690 

>>XP_011512361 (OMIM: 606501) PREDICTED: myotubularin-re  (743 aa)
 initn: 4297 init1: 1597 opt: 2728  Z-score: 3129.6  bits: 589.8 E(85289): 1.4e-167
Smith-Waterman score: 4451; 86.4% identity (86.4% similar) in 799 aa overlap (1-747:1-743)

               10        20        30        40        50        60
pF1KA1 MLGKGVVGGGGGTKAPKPSFVSYVRPEEIHTNEKEVTEKEVTLHLLPGEQLLCEASTVLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLGKGVVGGGGGTKAPKPSFVSYVRPEEIHTNEKEVTEKEVTLHLLPGEQLLCEASTVLK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA1 YVQEDSCQHGVYGRLVCTDFKIAFLGDDESALDNDETQFKNKVIGENDITLHCVDQIYGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YVQEDSCQHGVYGRLVCTDFKIAFLGDDESALDNDETQFKNKVIGENDITLHCVDQIYGV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA1 FDEKKKTLFGQLKKYPEKLIIHCKDLRVFQFCLRYTKEEEVKRIVSGIIHHTQAPKLLKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FDEKKKTLFGQLKKYPEKLIIHCKDLRVFQFCLRYTKEEEVKRIVSGIIHHTQAPKLLKR
              130       140       150       160       170       180

              190       200       210       220       230          
pF1KA1 LFLFSYATAAQNNTVTDPKNHTVMFDTLKDWCWELERTKGNMKYKAVSVNEGYKVCER--
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::   
XP_011 LFLFSYATAAQNNTVTDPKNHTVMFDTLKDWCWELERTKGNMKYKAVSVNEGYKVCESVT
              190       200       210       220       230       240

                                    240       250       260        
pF1KA1 ------------------------------LPAYFVVPTPLPEENVQRFQGHGIPIWCWS
                                     ::::::::::::::::::::::::::::::
XP_011 RWLASKRSSINRRQKEKPHLYLEGDLRQFGLPAYFVVPTPLPEENVQRFQGHGIPIWCWS
              250       260       270       280       290       300

      270       280       290       300       310       320        
pF1KA1 CHNGSALLKMSALPKEQDDGILQIQKSFLDGIYKTIHRPPYEIVKTEDLSSNFLSLQEIQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CHNGSALLKMSALPKEQDDGILQIQKSFLDGIYKTIHRPPYEIVKTEDLSSNFLSLQEIQ
              310       320       330       340       350       360

      330       340       350       360       370       380        
pF1KA1 TAYSKFKQLFLIDNSTEFWDTDIKWFSLLESSSWLDIIRRCLKKAIEITECMEAQNMNVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TAYSKFKQLFLIDNSTEFWDTDIKWFSLLESSSWLDIIRRCLKKAIEITECMEAQNMNVL
              370       380       390       400       410       420

      390       400       410       420       430       440        
pF1KA1 LLEENASDLCCLISSLVQLMMDPHCRTRIGFQSLIQKEWVMGGHCFLDRCNHLRQNDKEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLEENASDLCCLISSLVQLMMDPHCRTRIGFQSLIQKEWVMGGHCFLDRCNHLRQNDKEE
              430       440       450       460       470       480

      450       460       470       480       490       500        
pF1KA1 VPVFLLFLDCVWQLVHQHPPAFEFTETYLTVLSDSLYIPIFSTFFFNSPHQKDTNMGREG
                                                               ::::
XP_011 --------------------------------------------------------GREG
                                                                   

      510       520       530       540       550                  
pF1KA1 QDTQSKPLNLLTVWDWSVQFEPKAQTLLKNPLYVEKPKLDKGQRKGMRFK----------
       ::::::::::::::::::::::::::::::::::::::::::::::::::          
XP_011 QDTQSKPLNLLTVWDWSVQFEPKAQTLLKNPLYVEKPKLDKGQRKGMRFKLCLQAQNFSP
          490       500       510       520       530       540    

                560       570       580       590       600        
pF1KA1 ----------HQRQLSLPLTQSKSSPKRGFFREETDHLIKNLLGKRISKLINSSDELQDN
                 ::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TESTKERAVMHQRQLSLPLTQSKSSPKRGFFREETDHLIKNLLGKRISKLINSSDELQDN
          550       560       570       580       590       600    

      610       620       630       640       650       660        
pF1KA1 FREFYDSWHSKSTDYHGLLLPHIEGPEIKVWAQRYLRWIPEAQILGGGQVATLSKLLEMM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FREFYDSWHSKSTDYHGLLLPHIEGPEIKVWAQRYLRWIPEAQILGGGQVATLSKLLEMM
          610       620       630       640       650       660    

      670       680       690       700       710       720        
pF1KA1 EEVQSLQEKIDERHHSQQAPQAEAPCLLRNSARLSSLFPFALLQRHSSKPVLPTSGWKAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEVQSLQEKIDERHHSQQAPQAEAPCLLRNSARLSSLFPFALLQRHSSKPVLPTSGWKAL
          670       680       690       700       710       720    

      730       740       
pF1KA1 GDEDDLAKREDEFVDLGDV
       :::::::::::::::::::
XP_011 GDEDDLAKREDEFVDLGDV
          730       740   




747 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Wed Nov  2 21:49:42 2016 done: Wed Nov  2 21:49:44 2016
 Total Scan time: 11.340 Total Display time:  0.220

Function used was FASTA [36.3.4 Apr, 2011]
Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.com