Result of FASTA (omim) for pF1KA1154
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KA1154, 476 aa
  1>>>pF1KA1154 476 - 476 aa - 476 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 8.1499+/-0.000403; mu= 5.1983+/- 0.025
 mean_var=181.2483+/-36.683, 0's: 0 Z-trim(118.0): 35  B-trim: 1662 in 1/54
 Lambda= 0.095266
 statistics sampled from 30577 (30612) to 30577 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.697), E-opt: 0.2 (0.359), width:  16
 Scan time: 10.830

The best scores are:                                      opt bits E(85289)
NP_001182539 (OMIM: 605755,610212,610212,616217) d ( 476) 3093 437.6 3.6e-122
NP_057440 (OMIM: 605755,610212,610212,616217) doub ( 476) 3093 437.6 3.6e-122
XP_016876336 (OMIM: 604742) PREDICTED: serine/thre ( 708)  367 63.0   3e-09
NP_004725 (OMIM: 604742) serine/threonine-protein  ( 729)  367 63.1 3.1e-09
NP_001317000 (OMIM: 604742) serine/threonine-prote ( 740)  367 63.1 3.1e-09
NP_001317001 (OMIM: 604742) serine/threonine-prote ( 740)  367 63.1 3.1e-09
XP_016876337 (OMIM: 604742) PREDICTED: serine/thre ( 363)  341 59.3 2.1e-08
NP_835366 (OMIM: 300067,300121) neuronal migration ( 360)  323 56.8 1.2e-07
NP_835364 (OMIM: 300067,300121) neuronal migration ( 360)  323 56.8 1.2e-07
XP_011529180 (OMIM: 300067,300121) PREDICTED: neur ( 361)  323 56.8 1.2e-07
NP_000546 (OMIM: 300067,300121) neuronal migration ( 441)  323 56.8 1.4e-07
XP_011529181 (OMIM: 300067,300121) PREDICTED: neur ( 324)  318 56.1 1.7e-07
XP_005262842 (OMIM: 613166) PREDICTED: serine/thre ( 782)  321 56.8 2.6e-07
XP_016863322 (OMIM: 613166) PREDICTED: serine/thre ( 694)  319 56.4 2.9e-07
XP_016863321 (OMIM: 613166) PREDICTED: serine/thre ( 717)  319 56.5 2.9e-07
NP_001035351 (OMIM: 613166) serine/threonine-prote ( 783)  319 56.5 3.2e-07
NP_835365 (OMIM: 300067,300121) neuronal migration ( 365)  308 54.7   5e-07
XP_016884801 (OMIM: 300067,300121) PREDICTED: neur ( 366)  308 54.7   5e-07
NP_001182482 (OMIM: 300067,300121) neuronal migrat ( 366)  308 54.7   5e-07
XP_011529182 (OMIM: 300067,300121) PREDICTED: neur ( 319)  306 54.4 5.4e-07
XP_005262843 (OMIM: 613166) PREDICTED: serine/thre ( 765)  312 55.5   6e-07
NP_001035350 (OMIM: 613166) serine/threonine-prote ( 766)  311 55.4 6.6e-07
XP_016869211 (OMIM: 180100,603937) PREDICTED: oxyg (2156)  303 54.6 3.2e-06
NP_006260 (OMIM: 180100,603937) oxygen-regulated p (2156)  303 54.6 3.2e-06
XP_016869210 (OMIM: 180100,603937) PREDICTED: oxyg (2163)  303 54.6 3.2e-06
NP_849188 (OMIM: 608581,613587) retinitis pigmento (2400)  240 46.0  0.0014


>>NP_001182539 (OMIM: 605755,610212,610212,616217) doubl  (476 aa)
 initn: 3093 init1: 3093 opt: 3093  Z-score: 2314.2  bits: 437.6 E(85289): 3.6e-122
Smith-Waterman score: 3093; 99.8% identity (100.0% similar) in 476 aa overlap (1-476:1-476)

               10        20        30        40        50        60
pF1KA1 MSGSSARSSHLSQPVVKSVLVYRNGDPFYAGRRVVIHEKKVSSFEVFLKEVTGGVQAPFG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSGSSARSSHLSQPVVKSVLVYRNGDPFYAGRRVVIHEKKVSSFEVFLKEVTGGVQAPFG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA1 AVRNIYTPRTGHRIRKLDQIQSGGNYVAGGQEAFKKLNYLDIGEIKKRPMEVVNTEVKPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVRNIYTPRTGHRIRKLDQIQSGGNYVAGGQEAFKKLNYLDIGEIKKRPMEVVNTEVKPV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA1 IHSRINVSARFRKPLQEPCTIFLIANGDLINPASRLLIPRKTLNQWDHVLQMVTEKITLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IHSRINVSARFRKPLQEPCTIFLIANGDLINPASRLLIPRKTLNQWDHVLQMVTEKITLR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA1 SGAVHRLYTLEGKLVESGAELENGQFYVAVGRDKFKKLPYGELLFDKSTMRRPFGQKASS
       ::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::
NP_001 SGAVHRLYTLEGKLVESGAELENGQFYVAVGRDKFKKLPYSELLFDKSTMRRPFGQKASS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA1 LPPIVGSRKSKGSGNDRHSKSTVGSSDNSSPQPLKRKGKKEDVNSEKLTKLKQNVKLKNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPPIVGSRKSKGSGNDRHSKSTVGSSDNSSPQPLKRKGKKEDVNSEKLTKLKQNVKLKNS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA1 QETIPNSDEGIFKAGAERSETRGAAEVQEDEDTQVEVPVDQRPAEIVDEEEDGEKANKDA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QETIPNSDEGIFKAGAERSETRGAAEVQEDEDTQVEVPVDQRPAEIVDEEEDGEKANKDA
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA1 EQKEDFSGMNGDLEEEGGREATDAPEQVEEILDHSEQQARPARVNGGTDEENGEELQQVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EQKEDFSGMNGDLEEEGGREATDAPEQVEEILDHSEQQARPARVNGGTDEENGEELQQVN
              370       380       390       400       410       420

              430       440       450       460       470      
pF1KA1 NELQLVLDKERKSQGAGSGQDEADVDPQRPPRPEVKITSPEENENNQQNKDYAAVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NELQLVLDKERKSQGAGSGQDEADVDPQRPPRPEVKITSPEENENNQQNKDYAAVA
              430       440       450       460       470      

>>NP_057440 (OMIM: 605755,610212,610212,616217) doubleco  (476 aa)
 initn: 3093 init1: 3093 opt: 3093  Z-score: 2314.2  bits: 437.6 E(85289): 3.6e-122
Smith-Waterman score: 3093; 99.8% identity (100.0% similar) in 476 aa overlap (1-476:1-476)

               10        20        30        40        50        60
pF1KA1 MSGSSARSSHLSQPVVKSVLVYRNGDPFYAGRRVVIHEKKVSSFEVFLKEVTGGVQAPFG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MSGSSARSSHLSQPVVKSVLVYRNGDPFYAGRRVVIHEKKVSSFEVFLKEVTGGVQAPFG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA1 AVRNIYTPRTGHRIRKLDQIQSGGNYVAGGQEAFKKLNYLDIGEIKKRPMEVVNTEVKPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 AVRNIYTPRTGHRIRKLDQIQSGGNYVAGGQEAFKKLNYLDIGEIKKRPMEVVNTEVKPV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA1 IHSRINVSARFRKPLQEPCTIFLIANGDLINPASRLLIPRKTLNQWDHVLQMVTEKITLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 IHSRINVSARFRKPLQEPCTIFLIANGDLINPASRLLIPRKTLNQWDHVLQMVTEKITLR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA1 SGAVHRLYTLEGKLVESGAELENGQFYVAVGRDKFKKLPYGELLFDKSTMRRPFGQKASS
       ::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::
NP_057 SGAVHRLYTLEGKLVESGAELENGQFYVAVGRDKFKKLPYSELLFDKSTMRRPFGQKASS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA1 LPPIVGSRKSKGSGNDRHSKSTVGSSDNSSPQPLKRKGKKEDVNSEKLTKLKQNVKLKNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 LPPIVGSRKSKGSGNDRHSKSTVGSSDNSSPQPLKRKGKKEDVNSEKLTKLKQNVKLKNS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA1 QETIPNSDEGIFKAGAERSETRGAAEVQEDEDTQVEVPVDQRPAEIVDEEEDGEKANKDA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 QETIPNSDEGIFKAGAERSETRGAAEVQEDEDTQVEVPVDQRPAEIVDEEEDGEKANKDA
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA1 EQKEDFSGMNGDLEEEGGREATDAPEQVEEILDHSEQQARPARVNGGTDEENGEELQQVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 EQKEDFSGMNGDLEEEGGREATDAPEQVEEILDHSEQQARPARVNGGTDEENGEELQQVN
              370       380       390       400       410       420

              430       440       450       460       470      
pF1KA1 NELQLVLDKERKSQGAGSGQDEADVDPQRPPRPEVKITSPEENENNQQNKDYAAVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 NELQLVLDKERKSQGAGSGQDEADVDPQRPPRPEVKITSPEENENNQQNKDYAAVA
              430       440       450       460       470      

>>XP_016876336 (OMIM: 604742) PREDICTED: serine/threonin  (708 aa)
 initn: 277 init1: 123 opt: 367  Z-score: 287.0  bits: 63.0 E(85289): 3e-09
Smith-Waterman score: 367; 30.6% identity (56.9% similar) in 353 aa overlap (12-342:52-389)

                                  10        20        30        40 
pF1KA1                    MSGSSARSSHLSQPVVKSVLVYRNGDPFYAGRRVVIHEKKV
                                     :.  .:.:  ::::: .. :   .:   . 
XP_016 SRGSRVNGLPSPTHSAHCSFYRTRTLQTLSSEKKAKKVRFYRNGDRYFKGIVYAISPDRF
              30        40        50        60        70        80 

              50            60        70        80        90       
pF1KA1 SSFEVFLKEVT----GGVQAPFGAVRNIYTPRTGHRIRKLDQIQSGGNYVAGGQEAFKKL
        :::..: ..:     .:. : : ::.:::    ..: .:::.  : .:: :. : ::::
XP_016 RSFEALLADLTRTLSDNVNLPQG-VRTIYTIDGLKKISSLDQLVEGESYVCGSIEPFKKL
              90       100        110       120       130       140

       100       110       120                 130       140       
pF1KA1 NYLDIGEIKKRPMEVVNTEVKPVIHSRINVS----------ARFRKPLQEPCTIFLIANG
       .:      .  :   ::  :: .  ::   :          .:  : . .:  . .: .:
XP_016 EYTK----NVNPNWSVN--VKTTSASRAVSSLATAKGSPSEVRENKDFIRPKLVTIIRSG
                  150         160       170       180       190    

       150       160       170       180       190       200       
pF1KA1 DLINPASRLLIPRKTLNQWDHVLQMVTEKITLRSGAVHRLYTLEGKLVESGAELE-NGQF
            : :.:. .:: .....::  .:. : : ::.:.:::::.:: :    ..  . ..
XP_016 VKPRKAVRILLNKKTAHSFEQVLTDITDAIKLDSGVVKRLYTLDGKQVMCLQDFFGDDDI
          200       210       220       230       240       250    

        210       220       230       240        250         260   
pF1KA1 YVAVGRDKFKKLPYGELLFDKSTMRRPFGQKASSLPPIVGS-RKS--KGSGNDRHSKSTV
       ..: : .::.     ..:.:.:  :     :..:   :..: :.:  :. : .:.::: .
XP_016 FIACGPEKFRY--QDDFLLDESECRV---VKSTSYTKIASSSRRSTTKSPGPSRRSKSPA
          260         270          280       290       300         

            270          280       290       300       310         
pF1KA1 GSSD-NSSPQP---LKRKGKKEDVNSEKLTKLKQNVKLKNSQETIPNSDEGIFKAGAERS
       ..:. :..:       :.::. . .  .  .:.   : ..::.   ... .  :. .  .
XP_016 STSSVNGTPGSQLSTPRSGKSPSPSPTSPGSLR---KQRSSQHGGSSTSLASTKVCSSMD
     310       320       330       340          350       360      

     320       330       340       350       360       370         
pF1KA1 ETRGAAEVQEDEDTQVEVPVDQRPAEIVDEEEDGEKANKDAEQKEDFSGMNGDLEEEGGR
       :. : .:   .:  :. . . .:                                     
XP_016 ENDGPGEEVSEEGFQIPATITERYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKC
        370       380       390       400       410       420      

>>NP_004725 (OMIM: 604742) serine/threonine-protein kina  (729 aa)
 initn: 277 init1: 123 opt: 367  Z-score: 286.8  bits: 63.1 E(85289): 3.1e-09
Smith-Waterman score: 367; 30.6% identity (56.9% similar) in 353 aa overlap (12-342:52-389)

                                  10        20        30        40 
pF1KA1                    MSGSSARSSHLSQPVVKSVLVYRNGDPFYAGRRVVIHEKKV
                                     :.  .:.:  ::::: .. :   .:   . 
NP_004 SRGSRVNGLPSPTHSAHCSFYRTRTLQTLSSEKKAKKVRFYRNGDRYFKGIVYAISPDRF
              30        40        50        60        70        80 

              50            60        70        80        90       
pF1KA1 SSFEVFLKEVT----GGVQAPFGAVRNIYTPRTGHRIRKLDQIQSGGNYVAGGQEAFKKL
        :::..: ..:     .:. : : ::.:::    ..: .:::.  : .:: :. : ::::
NP_004 RSFEALLADLTRTLSDNVNLPQG-VRTIYTIDGLKKISSLDQLVEGESYVCGSIEPFKKL
              90       100        110       120       130       140

       100       110       120                 130       140       
pF1KA1 NYLDIGEIKKRPMEVVNTEVKPVIHSRINVS----------ARFRKPLQEPCTIFLIANG
       .:      .  :   ::  :: .  ::   :          .:  : . .:  . .: .:
NP_004 EYTK----NVNPNWSVN--VKTTSASRAVSSLATAKGSPSEVRENKDFIRPKLVTIIRSG
                  150         160       170       180       190    

       150       160       170       180       190       200       
pF1KA1 DLINPASRLLIPRKTLNQWDHVLQMVTEKITLRSGAVHRLYTLEGKLVESGAELE-NGQF
            : :.:. .:: .....::  .:. : : ::.:.:::::.:: :    ..  . ..
NP_004 VKPRKAVRILLNKKTAHSFEQVLTDITDAIKLDSGVVKRLYTLDGKQVMCLQDFFGDDDI
          200       210       220       230       240       250    

        210       220       230       240        250         260   
pF1KA1 YVAVGRDKFKKLPYGELLFDKSTMRRPFGQKASSLPPIVGS-RKS--KGSGNDRHSKSTV
       ..: : .::.     ..:.:.:  :     :..:   :..: :.:  :. : .:.::: .
NP_004 FIACGPEKFRY--QDDFLLDESECRV---VKSTSYTKIASSSRRSTTKSPGPSRRSKSPA
          260         270          280       290       300         

            270          280       290       300       310         
pF1KA1 GSSD-NSSPQP---LKRKGKKEDVNSEKLTKLKQNVKLKNSQETIPNSDEGIFKAGAERS
       ..:. :..:       :.::. . .  .  .:.   : ..::.   ... .  :. .  .
NP_004 STSSVNGTPGSQLSTPRSGKSPSPSPTSPGSLR---KQRSSQHGGSSTSLASTKVCSSMD
     310       320       330       340          350       360      

     320       330       340       350       360       370         
pF1KA1 ETRGAAEVQEDEDTQVEVPVDQRPAEIVDEEEDGEKANKDAEQKEDFSGMNGDLEEEGGR
       :. : .:   .:  :. . . .:                                     
NP_004 ENDGPGEEVSEEGFQIPATITERYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKC
        370       380       390       400       410       420      

>>NP_001317000 (OMIM: 604742) serine/threonine-protein k  (740 aa)
 initn: 312 init1: 123 opt: 367  Z-score: 286.7  bits: 63.1 E(85289): 3.1e-09
Smith-Waterman score: 367; 30.6% identity (56.9% similar) in 353 aa overlap (12-342:52-389)

                                  10        20        30        40 
pF1KA1                    MSGSSARSSHLSQPVVKSVLVYRNGDPFYAGRRVVIHEKKV
                                     :.  .:.:  ::::: .. :   .:   . 
NP_001 SRGSRVNGLPSPTHSAHCSFYRTRTLQTLSSEKKAKKVRFYRNGDRYFKGIVYAISPDRF
              30        40        50        60        70        80 

              50            60        70        80        90       
pF1KA1 SSFEVFLKEVT----GGVQAPFGAVRNIYTPRTGHRIRKLDQIQSGGNYVAGGQEAFKKL
        :::..: ..:     .:. : : ::.:::    ..: .:::.  : .:: :. : ::::
NP_001 RSFEALLADLTRTLSDNVNLPQG-VRTIYTIDGLKKISSLDQLVEGESYVCGSIEPFKKL
              90       100        110       120       130       140

       100       110       120                 130       140       
pF1KA1 NYLDIGEIKKRPMEVVNTEVKPVIHSRINVS----------ARFRKPLQEPCTIFLIANG
       .:      .  :   ::  :: .  ::   :          .:  : . .:  . .: .:
NP_001 EYTK----NVNPNWSVN--VKTTSASRAVSSLATAKGSPSEVRENKDFIRPKLVTIIRSG
                  150         160       170       180       190    

       150       160       170       180       190       200       
pF1KA1 DLINPASRLLIPRKTLNQWDHVLQMVTEKITLRSGAVHRLYTLEGKLVESGAELE-NGQF
            : :.:. .:: .....::  .:. : : ::.:.:::::.:: :    ..  . ..
NP_001 VKPRKAVRILLNKKTAHSFEQVLTDITDAIKLDSGVVKRLYTLDGKQVMCLQDFFGDDDI
          200       210       220       230       240       250    

        210       220       230       240        250         260   
pF1KA1 YVAVGRDKFKKLPYGELLFDKSTMRRPFGQKASSLPPIVGS-RKS--KGSGNDRHSKSTV
       ..: : .::.     ..:.:.:  :     :..:   :..: :.:  :. : .:.::: .
NP_001 FIACGPEKFRY--QDDFLLDESECRV---VKSTSYTKIASSSRRSTTKSPGPSRRSKSPA
          260         270          280       290       300         

            270          280       290       300       310         
pF1KA1 GSSD-NSSPQP---LKRKGKKEDVNSEKLTKLKQNVKLKNSQETIPNSDEGIFKAGAERS
       ..:. :..:       :.::. . .  .  .:.   : ..::.   ... .  :. .  .
NP_001 STSSVNGTPGSQLSTPRSGKSPSPSPTSPGSLR---KQRSSQHGGSSTSLASTKVCSSMD
     310       320       330       340          350       360      

     320       330       340       350       360       370         
pF1KA1 ETRGAAEVQEDEDTQVEVPVDQRPAEIVDEEEDGEKANKDAEQKEDFSGMNGDLEEEGGR
       :. : .:   .:  :. . . .:                                     
NP_001 ENDGPGEEVSEEGFQIPATITERYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKC
        370       380       390       400       410       420      

>>NP_001317001 (OMIM: 604742) serine/threonine-protein k  (740 aa)
 initn: 312 init1: 123 opt: 367  Z-score: 286.7  bits: 63.1 E(85289): 3.1e-09
Smith-Waterman score: 367; 30.6% identity (56.9% similar) in 353 aa overlap (12-342:52-389)

                                  10        20        30        40 
pF1KA1                    MSGSSARSSHLSQPVVKSVLVYRNGDPFYAGRRVVIHEKKV
                                     :.  .:.:  ::::: .. :   .:   . 
NP_001 SRGSRVNGLPSPTHSAHCSFYRTRTLQTLSSEKKAKKVRFYRNGDRYFKGIVYAISPDRF
              30        40        50        60        70        80 

              50            60        70        80        90       
pF1KA1 SSFEVFLKEVT----GGVQAPFGAVRNIYTPRTGHRIRKLDQIQSGGNYVAGGQEAFKKL
        :::..: ..:     .:. : : ::.:::    ..: .:::.  : .:: :. : ::::
NP_001 RSFEALLADLTRTLSDNVNLPQG-VRTIYTIDGLKKISSLDQLVEGESYVCGSIEPFKKL
              90       100        110       120       130       140

       100       110       120                 130       140       
pF1KA1 NYLDIGEIKKRPMEVVNTEVKPVIHSRINVS----------ARFRKPLQEPCTIFLIANG
       .:      .  :   ::  :: .  ::   :          .:  : . .:  . .: .:
NP_001 EYTK----NVNPNWSVN--VKTTSASRAVSSLATAKGSPSEVRENKDFIRPKLVTIIRSG
                  150         160       170       180       190    

       150       160       170       180       190       200       
pF1KA1 DLINPASRLLIPRKTLNQWDHVLQMVTEKITLRSGAVHRLYTLEGKLVESGAELE-NGQF
            : :.:. .:: .....::  .:. : : ::.:.:::::.:: :    ..  . ..
NP_001 VKPRKAVRILLNKKTAHSFEQVLTDITDAIKLDSGVVKRLYTLDGKQVMCLQDFFGDDDI
          200       210       220       230       240       250    

        210       220       230       240        250         260   
pF1KA1 YVAVGRDKFKKLPYGELLFDKSTMRRPFGQKASSLPPIVGS-RKS--KGSGNDRHSKSTV
       ..: : .::.     ..:.:.:  :     :..:   :..: :.:  :. : .:.::: .
NP_001 FIACGPEKFRY--QDDFLLDESECRV---VKSTSYTKIASSSRRSTTKSPGPSRRSKSPA
          260         270          280       290       300         

            270          280       290       300       310         
pF1KA1 GSSD-NSSPQP---LKRKGKKEDVNSEKLTKLKQNVKLKNSQETIPNSDEGIFKAGAERS
       ..:. :..:       :.::. . .  .  .:.   : ..::.   ... .  :. .  .
NP_001 STSSVNGTPGSQLSTPRSGKSPSPSPTSPGSLR---KQRSSQHGGSSTSLASTKVCSSMD
     310       320       330       340          350       360      

     320       330       340       350       360       370         
pF1KA1 ETRGAAEVQEDEDTQVEVPVDQRPAEIVDEEEDGEKANKDAEQKEDFSGMNGDLEEEGGR
       :. : .:   .:  :. . . .:                                     
NP_001 ENDGPGEEVSEEGFQIPATITERYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKC
        370       380       390       400       410       420      

>>XP_016876337 (OMIM: 604742) PREDICTED: serine/threonin  (363 aa)
 initn: 299 init1: 123 opt: 341  Z-score: 271.7  bits: 59.3 E(85289): 2.1e-08
Smith-Waterman score: 341; 33.7% identity (58.4% similar) in 279 aa overlap (12-271:52-318)

                                  10        20        30        40 
pF1KA1                    MSGSSARSSHLSQPVVKSVLVYRNGDPFYAGRRVVIHEKKV
                                     :.  .:.:  ::::: .. :   .:   . 
XP_016 SRGSRVNGLPSPTHSAHCSFYRTRTLQTLSSEKKAKKVRFYRNGDRYFKGIVYAISPDRF
              30        40        50        60        70        80 

              50            60        70        80        90       
pF1KA1 SSFEVFLKEVT----GGVQAPFGAVRNIYTPRTGHRIRKLDQIQSGGNYVAGGQEAFKKL
        :::..: ..:     .:. : : ::.:::    ..: .:::.  : .:: :. : ::::
XP_016 RSFEALLADLTRTLSDNVNLPQG-VRTIYTIDGLKKISSLDQLVEGESYVCGSIEPFKKL
              90       100        110       120       130       140

       100       110       120                 130       140       
pF1KA1 NYLDIGEIKKRPMEVVNTEVKPVIHSRINVS----------ARFRKPLQEPCTIFLIANG
       .:      .  :   ::  :: .  ::   :          .:  : . .:  . .: .:
XP_016 EYTK----NVNPNWSVN--VKTTSASRAVSSLATAKGSPSEVRENKDFIRPKLVTIIRSG
                  150         160       170       180       190    

       150       160       170       180       190       200       
pF1KA1 DLINPASRLLIPRKTLNQWDHVLQMVTEKITLRSGAVHRLYTLEGKLVESGAELE-NGQF
            : :.:. .:: .....::  .:. : : ::.:.:::::.:: :    ..  . ..
XP_016 VKPRKAVRILLNKKTAHSFEQVLTDITDAIKLDSGVVKRLYTLDGKQVMCLQDFFGDDDI
          200       210       220       230       240       250    

        210       220       230       240        250         260   
pF1KA1 YVAVGRDKFKKLPYGELLFDKSTMRRPFGQKASSLPPIVGS-RKS--KGSGNDRHSKSTV
       ..: : .::.     ..:.:.:  :     :..:   :..: :.:  :. : .:.::: .
XP_016 FIACGPEKFRY--QDDFLLDESECRVV---KSTSYTKIASSSRRSTTKSPGPSRRSKSPA
          260         270          280       290       300         

            270       280       290       300       310       320  
pF1KA1 GSSD-NSSPQPLKRKGKKEDVNSEKLTKLKQNVKLKNSQETIPNSDEGIFKAGAERSETR
       ..:. :..:                                                   
XP_016 STSSVNGTPGSQLSTPRSGKSPSPSPTSPGSLRKQRDLYRPLSSDDLDSVGDSV      
     310       320       330       340       350       360         

>>NP_835366 (OMIM: 300067,300121) neuronal migration pro  (360 aa)
 initn: 239 init1: 102 opt: 323  Z-score: 258.4  bits: 56.8 E(85289): 1.2e-07
Smith-Waterman score: 323; 27.4% identity (61.9% similar) in 281 aa overlap (17-285:53-331)

                             10        20        30        40      
pF1KA1               MSGSSARSSHLSQPVVKSVLVYRNGDPFYAGRRVVIHEKKVSSFEV
                                     :.:  ::::: .. :   ..   .  ::..
NP_835 MNGLPSPTHSAHCSFYRTRTLQALSNEKKAKKVRFYRNGDRYFKGIVYAVSSDRFRSFDA
             30        40        50        60        70        80  

         50            60        70        80        90       100  
pF1KA1 FLKEVT----GGVQAPFGAVRNIYTPRTGHRIRKLDQIQSGGNYVAGGQEAFKKLNYL-D
       .: ..:     ... : : :: :::   ...: ..:... : .:: .... :::..:  .
NP_835 LLADLTRSLSDNINLPQG-VRYIYTIDGSRKIGSMDELEEGESYVCSSDNFFKKVEYTKN
             90       100        110       120       130       140 

             110        120       130       140       150       160
pF1KA1 IGEIKKRPMEV-VNTEVKPVIHSRINVSARFRKPLQEPCTIFLIANGDLINPASRLLIPR
       ..   .  ... .: ..   . :  ...::  : . .:  . .: .:     : :.:. .
NP_835 VNPNWSVNVKTSANMKAPQSLASSNSAQARENKDFVRPKLVTIIRSGVKPRKAVRVLLNK
             150       160       170       180       190       200 

              170       180       190       200        210         
pF1KA1 KTLNQWDHVLQMVTEKITLRSGAVHRLYTLEGKLVESGAELE-NGQFYVAVGRDKFKKLP
       :: .....::  .:: : :..:.:..::::.:: :    ..  . . ..: : .::.   
NP_835 KTAHSFEQVLTDITEAIKLETGVVKKLYTLDGKQVTCLHDFFGDDDVFIACGPEKFR-YA
             210       220       230       240       250        260

     220       230        240          250       260       270     
pF1KA1 YGELLFDKSTMRRPFGQ-KASSLP---PIVGSRKSKGSGNDRHSKSTVGSSDNSSPQPLK
         .. .:..  :   :. .:.. :   :   . ..:. :  :.::: . :....: . :.
NP_835 QDDFSLDENECRVMKGNPSATAGPKASPTPQKTSAKSPGPMRRSKSPADSANGTSSSQLS
              270       280       290       300       310       320

          280       290       300       310       320       330    
pF1KA1 R-KGKKEDVNSEKLTKLKQNVKLKNSQETIPNSDEGIFKAGAERSETRGAAEVQEDEDTQ
         :.:.  ...                                                 
NP_835 TPKSKQSPISTPTSPGSLRKHKDLYLPLSLDDSDSLGDSM                    
              330       340       350       360                    

>>NP_835364 (OMIM: 300067,300121) neuronal migration pro  (360 aa)
 initn: 239 init1: 102 opt: 323  Z-score: 258.4  bits: 56.8 E(85289): 1.2e-07
Smith-Waterman score: 323; 27.4% identity (61.9% similar) in 281 aa overlap (17-285:53-331)

                             10        20        30        40      
pF1KA1               MSGSSARSSHLSQPVVKSVLVYRNGDPFYAGRRVVIHEKKVSSFEV
                                     :.:  ::::: .. :   ..   .  ::..
NP_835 MNGLPSPTHSAHCSFYRTRTLQALSNEKKAKKVRFYRNGDRYFKGIVYAVSSDRFRSFDA
             30        40        50        60        70        80  

         50            60        70        80        90       100  
pF1KA1 FLKEVT----GGVQAPFGAVRNIYTPRTGHRIRKLDQIQSGGNYVAGGQEAFKKLNYL-D
       .: ..:     ... : : :: :::   ...: ..:... : .:: .... :::..:  .
NP_835 LLADLTRSLSDNINLPQG-VRYIYTIDGSRKIGSMDELEEGESYVCSSDNFFKKVEYTKN
             90       100        110       120       130       140 

             110        120       130       140       150       160
pF1KA1 IGEIKKRPMEV-VNTEVKPVIHSRINVSARFRKPLQEPCTIFLIANGDLINPASRLLIPR
       ..   .  ... .: ..   . :  ...::  : . .:  . .: .:     : :.:. .
NP_835 VNPNWSVNVKTSANMKAPQSLASSNSAQARENKDFVRPKLVTIIRSGVKPRKAVRVLLNK
             150       160       170       180       190       200 

              170       180       190       200        210         
pF1KA1 KTLNQWDHVLQMVTEKITLRSGAVHRLYTLEGKLVESGAELE-NGQFYVAVGRDKFKKLP
       :: .....::  .:: : :..:.:..::::.:: :    ..  . . ..: : .::.   
NP_835 KTAHSFEQVLTDITEAIKLETGVVKKLYTLDGKQVTCLHDFFGDDDVFIACGPEKFR-YA
             210       220       230       240       250        260

     220       230        240          250       260       270     
pF1KA1 YGELLFDKSTMRRPFGQ-KASSLP---PIVGSRKSKGSGNDRHSKSTVGSSDNSSPQPLK
         .. .:..  :   :. .:.. :   :   . ..:. :  :.::: . :....: . :.
NP_835 QDDFSLDENECRVMKGNPSATAGPKASPTPQKTSAKSPGPMRRSKSPADSANGTSSSQLS
              270       280       290       300       310       320

          280       290       300       310       320       330    
pF1KA1 R-KGKKEDVNSEKLTKLKQNVKLKNSQETIPNSDEGIFKAGAERSETRGAAEVQEDEDTQ
         :.:.  ...                                                 
NP_835 TPKSKQSPISTPTSPGSLRKHKDLYLPLSLDDSDSLGDSM                    
              330       340       350       360                    

>>XP_011529180 (OMIM: 300067,300121) PREDICTED: neuronal  (361 aa)
 initn: 239 init1: 102 opt: 323  Z-score: 258.4  bits: 56.8 E(85289): 1.2e-07
Smith-Waterman score: 323; 27.4% identity (61.9% similar) in 281 aa overlap (17-285:53-331)

                             10        20        30        40      
pF1KA1               MSGSSARSSHLSQPVVKSVLVYRNGDPFYAGRRVVIHEKKVSSFEV
                                     :.:  ::::: .. :   ..   .  ::..
XP_011 MNGLPSPTHSAHCSFYRTRTLQALSNEKKAKKVRFYRNGDRYFKGIVYAVSSDRFRSFDA
             30        40        50        60        70        80  

         50            60        70        80        90       100  
pF1KA1 FLKEVT----GGVQAPFGAVRNIYTPRTGHRIRKLDQIQSGGNYVAGGQEAFKKLNYL-D
       .: ..:     ... : : :: :::   ...: ..:... : .:: .... :::..:  .
XP_011 LLADLTRSLSDNINLPQG-VRYIYTIDGSRKIGSMDELEEGESYVCSSDNFFKKVEYTKN
             90       100        110       120       130       140 

             110        120       130       140       150       160
pF1KA1 IGEIKKRPMEV-VNTEVKPVIHSRINVSARFRKPLQEPCTIFLIANGDLINPASRLLIPR
       ..   .  ... .: ..   . :  ...::  : . .:  . .: .:     : :.:. .
XP_011 VNPNWSVNVKTSANMKAPQSLASSNSAQARENKDFVRPKLVTIIRSGVKPRKAVRVLLNK
             150       160       170       180       190       200 

              170       180       190       200        210         
pF1KA1 KTLNQWDHVLQMVTEKITLRSGAVHRLYTLEGKLVESGAELE-NGQFYVAVGRDKFKKLP
       :: .....::  .:: : :..:.:..::::.:: :    ..  . . ..: : .::.   
XP_011 KTAHSFEQVLTDITEAIKLETGVVKKLYTLDGKQVTCLHDFFGDDDVFIACGPEKFR-YA
             210       220       230       240       250        260

     220       230        240          250       260       270     
pF1KA1 YGELLFDKSTMRRPFGQ-KASSLP---PIVGSRKSKGSGNDRHSKSTVGSSDNSSPQPLK
         .. .:..  :   :. .:.. :   :   . ..:. :  :.::: . :....: . :.
XP_011 QDDFSLDENECRVMKGNPSATAGPKASPTPQKTSAKSPGPMRRSKSPADSANGTSSSQLS
              270       280       290       300       310       320

          280       290       300       310       320       330    
pF1KA1 R-KGKKEDVNSEKLTKLKQNVKLKNSQETIPNSDEGIFKAGAERSETRGAAEVQEDEDTQ
         :.:.  ...                                                 
XP_011 TPKSKQSPISTPTSPGSLRKHKVDLYLPLSLDDSDSLGDSM                   
              330       340       350       360                    




476 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Wed Nov  2 20:39:11 2016 done: Wed Nov  2 20:39:12 2016
 Total Scan time: 10.830 Total Display time:  0.060

Function used was FASTA [36.3.4 Apr, 2011]
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