Result of FASTA (omim) for pF1KA0471
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KA0471, 370 aa
  1>>>pF1KA0471 370 - 370 aa - 370 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 9.7747+/-0.000459; mu= -3.1584+/- 0.028
 mean_var=359.4191+/-74.416, 0's: 0 Z-trim(119.8): 55  B-trim: 593 in 2/53
 Lambda= 0.067651
 statistics sampled from 34100 (34156) to 34100 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.721), E-opt: 0.2 (0.4), width:  16
 Scan time:  7.910

The best scores are:                                      opt bits E(85289)
NP_001230694 (OMIM: 609238) rab GTPase-activating  ( 370) 2372 245.4 1.6e-64
XP_005245738 (OMIM: 609238) PREDICTED: rab GTPase- (1014) 1997 209.3 3.2e-53
XP_011508525 (OMIM: 609238) PREDICTED: rab GTPase- (1051) 1997 209.3 3.3e-53
XP_005245737 (OMIM: 609238) PREDICTED: rab GTPase- (1051) 1997 209.3 3.3e-53
NP_001317918 (OMIM: 609238) rab GTPase-activating  ( 308) 1708 180.5 4.5e-45
XP_016858485 (OMIM: 609238) PREDICTED: rab GTPase- ( 308) 1708 180.5 4.5e-45
XP_016858486 (OMIM: 609238) PREDICTED: rab GTPase- ( 308) 1708 180.5 4.5e-45
XP_016858487 (OMIM: 609238) PREDICTED: rab GTPase- ( 253) 1504 160.5 3.9e-39
NP_001230693 (OMIM: 609238) rab GTPase-activating  ( 253) 1504 160.5 3.9e-39
XP_016870059 (OMIM: 615882) PREDICTED: rab GTPase- ( 900) 1384 149.4   3e-35
XP_011516744 (OMIM: 615882) PREDICTED: rab GTPase- ( 900) 1384 149.4   3e-35
XP_016870057 (OMIM: 615882) PREDICTED: rab GTPase- (1069) 1384 149.5 3.4e-35
NP_036329 (OMIM: 615882) rab GTPase-activating pro (1069) 1384 149.5 3.4e-35
XP_011516743 (OMIM: 615882) PREDICTED: rab GTPase- (1069) 1384 149.5 3.4e-35
XP_016870058 (OMIM: 615882) PREDICTED: rab GTPase- (1069) 1384 149.5 3.4e-35
XP_016870056 (OMIM: 615882) PREDICTED: rab GTPase- (1069) 1384 149.5 3.4e-35
XP_011516742 (OMIM: 615882) PREDICTED: rab GTPase- (1069) 1384 149.5 3.4e-35
XP_006711756 (OMIM: 609238) PREDICTED: rab GTPase- ( 985) 1243 135.7 4.5e-31
XP_016858488 (OMIM: 609238) PREDICTED: rab GTPase- ( 242)  954 106.8 5.5e-23
XP_016858483 (OMIM: 609238) PREDICTED: rab GTPase- ( 778)  495 62.6 3.6e-09
NP_055672 (OMIM: 609238) rab GTPase-activating pro ( 815)  495 62.6 3.7e-09


>>NP_001230694 (OMIM: 609238) rab GTPase-activating prot  (370 aa)
 initn: 2372 init1: 2372 opt: 2372  Z-score: 1279.5  bits: 245.4 E(85289): 1.6e-64
Smith-Waterman score: 2372; 100.0% identity (100.0% similar) in 370 aa overlap (1-370:1-370)

               10        20        30        40        50        60
pF1KA0 MEEGVPCPAPAAKLTPPVKKSQDMHDERSKLVNEYACRVLELLGMGHRLFVPRLLATSKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEEGVPCPAPAAKLTPPVKKSQDMHDERSKLVNEYACRVLELLGMGHRLFVPRLLATSKE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 DLLQADFEGALKFFRVQLPKRYRAEENARRLMEQACNIKVPTKKLKKYEKEYQTMRESQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLLQADFEGALKFFRVQLPKRYRAEENARRLMEQACNIKVPTKKLKKYEKEYQTMRESQL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 QQEDPMDRYKRENRRLQEASMRLEQENDDLAHELVTSKIALRNDLDQAEDKADVLNKELL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQEDPMDRYKRENRRLQEASMRLEQENDDLAHELVTSKIALRNDLDQAEDKADVLNKELL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 LTKQRLVETEEEKRKQEEETAQLKEVFRKQLEKAEYEIKKTTAIIAEYKQICSQLSTRLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTKQRLVETEEEKRKQEEETAQLKEVFRKQLEKAEYEIKKTTAIIAEYKQICSQLSTRLE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 KQQAASKEELEVVKGKMMACKHCSDIFSKEGALKLAATGREDQGIETDDEKDSLKKQLRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KQQAASKEELEVVKGKMMACKHCSDIFSKEGALKLAATGREDQGIETDDEKDSLKKQLRE
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 MELELAQTKLQLVEAKCKIQELEHQRGALMNEIQAAKNSWFSKTLNSIKTATGTQPLQPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MELELAQTKLQLVEAKCKIQELEHQRGALMNEIQAAKNSWFSKTLNSIKTATGTQPLQPA
              310       320       330       340       350       360

              370
pF1KA0 PVTQPPKEST
       ::::::::::
NP_001 PVTQPPKEST
              370

>>XP_005245738 (OMIM: 609238) PREDICTED: rab GTPase-acti  (1014 aa)
 initn: 1997 init1: 1997 opt: 1997  Z-score: 1076.5  bits: 209.3 E(85289): 3.2e-53
Smith-Waterman score: 1997; 99.7% identity (99.7% similar) in 317 aa overlap (54-370:698-1014)

            30        40        50        60        70        80   
pF1KA0 MHDERSKLVNEYACRVLELLGMGHRLFVPRLLATSKEDLLQADFEGALKFFRVQLPKRYR
                                     :: :::::::::::::::::::::::::::
XP_005 TAKFPLCMVFHIIDLLLCEGLNIIFHVALALLKTSKEDLLQADFEGALKFFRVQLPKRYR
       670       680       690       700       710       720       

            90       100       110       120       130       140   
pF1KA0 AEENARRLMEQACNIKVPTKKLKKYEKEYQTMRESQLQQEDPMDRYKRENRRLQEASMRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AEENARRLMEQACNIKVPTKKLKKYEKEYQTMRESQLQQEDPMDRYKRENRRLQEASMRL
       730       740       750       760       770       780       

           150       160       170       180       190       200   
pF1KA0 EQENDDLAHELVTSKIALRNDLDQAEDKADVLNKELLLTKQRLVETEEEKRKQEEETAQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EQENDDLAHELVTSKIALRNDLDQAEDKADVLNKELLLTKQRLVETEEEKRKQEEETAQL
       790       800       810       820       830       840       

           210       220       230       240       250       260   
pF1KA0 KEVFRKQLEKAEYEIKKTTAIIAEYKQICSQLSTRLEKQQAASKEELEVVKGKMMACKHC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KEVFRKQLEKAEYEIKKTTAIIAEYKQICSQLSTRLEKQQAASKEELEVVKGKMMACKHC
       850       860       870       880       890       900       

           270       280       290       300       310       320   
pF1KA0 SDIFSKEGALKLAATGREDQGIETDDEKDSLKKQLREMELELAQTKLQLVEAKCKIQELE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SDIFSKEGALKLAATGREDQGIETDDEKDSLKKQLREMELELAQTKLQLVEAKCKIQELE
       910       920       930       940       950       960       

           330       340       350       360       370
pF1KA0 HQRGALMNEIQAAKNSWFSKTLNSIKTATGTQPLQPAPVTQPPKEST
       :::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HQRGALMNEIQAAKNSWFSKTLNSIKTATGTQPLQPAPVTQPPKEST
       970       980       990      1000      1010    

>>XP_011508525 (OMIM: 609238) PREDICTED: rab GTPase-acti  (1051 aa)
 initn: 1997 init1: 1997 opt: 1997  Z-score: 1076.3  bits: 209.3 E(85289): 3.3e-53
Smith-Waterman score: 1997; 99.7% identity (99.7% similar) in 317 aa overlap (54-370:735-1051)

            30        40        50        60        70        80   
pF1KA0 MHDERSKLVNEYACRVLELLGMGHRLFVPRLLATSKEDLLQADFEGALKFFRVQLPKRYR
                                     :: :::::::::::::::::::::::::::
XP_011 TAKFPLCMVFHIIDLLLCEGLNIIFHVALALLKTSKEDLLQADFEGALKFFRVQLPKRYR
          710       720       730       740       750       760    

            90       100       110       120       130       140   
pF1KA0 AEENARRLMEQACNIKVPTKKLKKYEKEYQTMRESQLQQEDPMDRYKRENRRLQEASMRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AEENARRLMEQACNIKVPTKKLKKYEKEYQTMRESQLQQEDPMDRYKRENRRLQEASMRL
          770       780       790       800       810       820    

           150       160       170       180       190       200   
pF1KA0 EQENDDLAHELVTSKIALRNDLDQAEDKADVLNKELLLTKQRLVETEEEKRKQEEETAQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EQENDDLAHELVTSKIALRNDLDQAEDKADVLNKELLLTKQRLVETEEEKRKQEEETAQL
          830       840       850       860       870       880    

           210       220       230       240       250       260   
pF1KA0 KEVFRKQLEKAEYEIKKTTAIIAEYKQICSQLSTRLEKQQAASKEELEVVKGKMMACKHC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KEVFRKQLEKAEYEIKKTTAIIAEYKQICSQLSTRLEKQQAASKEELEVVKGKMMACKHC
          890       900       910       920       930       940    

           270       280       290       300       310       320   
pF1KA0 SDIFSKEGALKLAATGREDQGIETDDEKDSLKKQLREMELELAQTKLQLVEAKCKIQELE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDIFSKEGALKLAATGREDQGIETDDEKDSLKKQLREMELELAQTKLQLVEAKCKIQELE
          950       960       970       980       990      1000    

           330       340       350       360       370
pF1KA0 HQRGALMNEIQAAKNSWFSKTLNSIKTATGTQPLQPAPVTQPPKEST
       :::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HQRGALMNEIQAAKNSWFSKTLNSIKTATGTQPLQPAPVTQPPKEST
         1010      1020      1030      1040      1050 

>>XP_005245737 (OMIM: 609238) PREDICTED: rab GTPase-acti  (1051 aa)
 initn: 1997 init1: 1997 opt: 1997  Z-score: 1076.3  bits: 209.3 E(85289): 3.3e-53
Smith-Waterman score: 1997; 99.7% identity (99.7% similar) in 317 aa overlap (54-370:735-1051)

            30        40        50        60        70        80   
pF1KA0 MHDERSKLVNEYACRVLELLGMGHRLFVPRLLATSKEDLLQADFEGALKFFRVQLPKRYR
                                     :: :::::::::::::::::::::::::::
XP_005 TAKFPLCMVFHIIDLLLCEGLNIIFHVALALLKTSKEDLLQADFEGALKFFRVQLPKRYR
          710       720       730       740       750       760    

            90       100       110       120       130       140   
pF1KA0 AEENARRLMEQACNIKVPTKKLKKYEKEYQTMRESQLQQEDPMDRYKRENRRLQEASMRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AEENARRLMEQACNIKVPTKKLKKYEKEYQTMRESQLQQEDPMDRYKRENRRLQEASMRL
          770       780       790       800       810       820    

           150       160       170       180       190       200   
pF1KA0 EQENDDLAHELVTSKIALRNDLDQAEDKADVLNKELLLTKQRLVETEEEKRKQEEETAQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EQENDDLAHELVTSKIALRNDLDQAEDKADVLNKELLLTKQRLVETEEEKRKQEEETAQL
          830       840       850       860       870       880    

           210       220       230       240       250       260   
pF1KA0 KEVFRKQLEKAEYEIKKTTAIIAEYKQICSQLSTRLEKQQAASKEELEVVKGKMMACKHC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KEVFRKQLEKAEYEIKKTTAIIAEYKQICSQLSTRLEKQQAASKEELEVVKGKMMACKHC
          890       900       910       920       930       940    

           270       280       290       300       310       320   
pF1KA0 SDIFSKEGALKLAATGREDQGIETDDEKDSLKKQLREMELELAQTKLQLVEAKCKIQELE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SDIFSKEGALKLAATGREDQGIETDDEKDSLKKQLREMELELAQTKLQLVEAKCKIQELE
          950       960       970       980       990      1000    

           330       340       350       360       370
pF1KA0 HQRGALMNEIQAAKNSWFSKTLNSIKTATGTQPLQPAPVTQPPKEST
       :::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HQRGALMNEIQAAKNSWFSKTLNSIKTATGTQPLQPAPVTQPPKEST
         1010      1020      1030      1040      1050 

>>NP_001317918 (OMIM: 609238) rab GTPase-activating prot  (308 aa)
 initn: 1708 init1: 1708 opt: 1708  Z-score: 930.2  bits: 180.5 E(85289): 4.5e-45
Smith-Waterman score: 1708; 100.0% identity (100.0% similar) in 271 aa overlap (100-370:38-308)

      70        80        90       100       110       120         
pF1KA0 ALKFFRVQLPKRYRAEENARRLMEQACNIKVPTKKLKKYEKEYQTMRESQLQQEDPMDRY
                                     ::::::::::::::::::::::::::::::
NP_001 MVAYDAHVFSQLHDEDFLTSLVAISKPRSMVPTKKLKKYEKEYQTMRESQLQQEDPMDRY
        10        20        30        40        50        60       

     130       140       150       160       170       180         
pF1KA0 KRENRRLQEASMRLEQENDDLAHELVTSKIALRNDLDQAEDKADVLNKELLLTKQRLVET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRENRRLQEASMRLEQENDDLAHELVTSKIALRNDLDQAEDKADVLNKELLLTKQRLVET
        70        80        90       100       110       120       

     190       200       210       220       230       240         
pF1KA0 EEEKRKQEEETAQLKEVFRKQLEKAEYEIKKTTAIIAEYKQICSQLSTRLEKQQAASKEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEEKRKQEEETAQLKEVFRKQLEKAEYEIKKTTAIIAEYKQICSQLSTRLEKQQAASKEE
       130       140       150       160       170       180       

     250       260       270       280       290       300         
pF1KA0 LEVVKGKMMACKHCSDIFSKEGALKLAATGREDQGIETDDEKDSLKKQLREMELELAQTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEVVKGKMMACKHCSDIFSKEGALKLAATGREDQGIETDDEKDSLKKQLREMELELAQTK
       190       200       210       220       230       240       

     310       320       330       340       350       360         
pF1KA0 LQLVEAKCKIQELEHQRGALMNEIQAAKNSWFSKTLNSIKTATGTQPLQPAPVTQPPKES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQLVEAKCKIQELEHQRGALMNEIQAAKNSWFSKTLNSIKTATGTQPLQPAPVTQPPKES
       250       260       270       280       290       300       

     370
pF1KA0 T
       :
NP_001 T
        

>>XP_016858485 (OMIM: 609238) PREDICTED: rab GTPase-acti  (308 aa)
 initn: 1708 init1: 1708 opt: 1708  Z-score: 930.2  bits: 180.5 E(85289): 4.5e-45
Smith-Waterman score: 1708; 100.0% identity (100.0% similar) in 271 aa overlap (100-370:38-308)

      70        80        90       100       110       120         
pF1KA0 ALKFFRVQLPKRYRAEENARRLMEQACNIKVPTKKLKKYEKEYQTMRESQLQQEDPMDRY
                                     ::::::::::::::::::::::::::::::
XP_016 MVAYDAHVFSQLHDEDFLTSLVAISKPRSMVPTKKLKKYEKEYQTMRESQLQQEDPMDRY
        10        20        30        40        50        60       

     130       140       150       160       170       180         
pF1KA0 KRENRRLQEASMRLEQENDDLAHELVTSKIALRNDLDQAEDKADVLNKELLLTKQRLVET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRENRRLQEASMRLEQENDDLAHELVTSKIALRNDLDQAEDKADVLNKELLLTKQRLVET
        70        80        90       100       110       120       

     190       200       210       220       230       240         
pF1KA0 EEEKRKQEEETAQLKEVFRKQLEKAEYEIKKTTAIIAEYKQICSQLSTRLEKQQAASKEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEEKRKQEEETAQLKEVFRKQLEKAEYEIKKTTAIIAEYKQICSQLSTRLEKQQAASKEE
       130       140       150       160       170       180       

     250       260       270       280       290       300         
pF1KA0 LEVVKGKMMACKHCSDIFSKEGALKLAATGREDQGIETDDEKDSLKKQLREMELELAQTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEVVKGKMMACKHCSDIFSKEGALKLAATGREDQGIETDDEKDSLKKQLREMELELAQTK
       190       200       210       220       230       240       

     310       320       330       340       350       360         
pF1KA0 LQLVEAKCKIQELEHQRGALMNEIQAAKNSWFSKTLNSIKTATGTQPLQPAPVTQPPKES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQLVEAKCKIQELEHQRGALMNEIQAAKNSWFSKTLNSIKTATGTQPLQPAPVTQPPKES
       250       260       270       280       290       300       

     370
pF1KA0 T
       :
XP_016 T
        

>>XP_016858486 (OMIM: 609238) PREDICTED: rab GTPase-acti  (308 aa)
 initn: 1708 init1: 1708 opt: 1708  Z-score: 930.2  bits: 180.5 E(85289): 4.5e-45
Smith-Waterman score: 1708; 100.0% identity (100.0% similar) in 271 aa overlap (100-370:38-308)

      70        80        90       100       110       120         
pF1KA0 ALKFFRVQLPKRYRAEENARRLMEQACNIKVPTKKLKKYEKEYQTMRESQLQQEDPMDRY
                                     ::::::::::::::::::::::::::::::
XP_016 MVAYDAHVFSQLHDEDFLTSLVAISKPRSMVPTKKLKKYEKEYQTMRESQLQQEDPMDRY
        10        20        30        40        50        60       

     130       140       150       160       170       180         
pF1KA0 KRENRRLQEASMRLEQENDDLAHELVTSKIALRNDLDQAEDKADVLNKELLLTKQRLVET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRENRRLQEASMRLEQENDDLAHELVTSKIALRNDLDQAEDKADVLNKELLLTKQRLVET
        70        80        90       100       110       120       

     190       200       210       220       230       240         
pF1KA0 EEEKRKQEEETAQLKEVFRKQLEKAEYEIKKTTAIIAEYKQICSQLSTRLEKQQAASKEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEEKRKQEEETAQLKEVFRKQLEKAEYEIKKTTAIIAEYKQICSQLSTRLEKQQAASKEE
       130       140       150       160       170       180       

     250       260       270       280       290       300         
pF1KA0 LEVVKGKMMACKHCSDIFSKEGALKLAATGREDQGIETDDEKDSLKKQLREMELELAQTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEVVKGKMMACKHCSDIFSKEGALKLAATGREDQGIETDDEKDSLKKQLREMELELAQTK
       190       200       210       220       230       240       

     310       320       330       340       350       360         
pF1KA0 LQLVEAKCKIQELEHQRGALMNEIQAAKNSWFSKTLNSIKTATGTQPLQPAPVTQPPKES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQLVEAKCKIQELEHQRGALMNEIQAAKNSWFSKTLNSIKTATGTQPLQPAPVTQPPKES
       250       260       270       280       290       300       

     370
pF1KA0 T
       :
XP_016 T
        

>>XP_016858487 (OMIM: 609238) PREDICTED: rab GTPase-acti  (253 aa)
 initn: 1503 init1: 1503 opt: 1504  Z-score: 823.6  bits: 160.5 E(85289): 3.9e-39
Smith-Waterman score: 1504; 98.4% identity (98.8% similar) in 245 aa overlap (126-370:9-253)

         100       110       120       130       140       150     
pF1KA0 CNIKVPTKKLKKYEKEYQTMRESQLQQEDPMDRYKRENRRLQEASMRLEQENDDLAHELV
                                     :   .:::::::::::::::::::::::::
XP_016                       MIENSSWSMTFEERENRRLQEASMRLEQENDDLAHELV
                                     10        20        30        

         160       170       180       190       200       210     
pF1KA0 TSKIALRNDLDQAEDKADVLNKELLLTKQRLVETEEEKRKQEEETAQLKEVFRKQLEKAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSKIALRNDLDQAEDKADVLNKELLLTKQRLVETEEEKRKQEEETAQLKEVFRKQLEKAE
       40        50        60        70        80        90        

         220       230       240       250       260       270     
pF1KA0 YEIKKTTAIIAEYKQICSQLSTRLEKQQAASKEELEVVKGKMMACKHCSDIFSKEGALKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YEIKKTTAIIAEYKQICSQLSTRLEKQQAASKEELEVVKGKMMACKHCSDIFSKEGALKL
      100       110       120       130       140       150        

         280       290       300       310       320       330     
pF1KA0 AATGREDQGIETDDEKDSLKKQLREMELELAQTKLQLVEAKCKIQELEHQRGALMNEIQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AATGREDQGIETDDEKDSLKKQLREMELELAQTKLQLVEAKCKIQELEHQRGALMNEIQA
      160       170       180       190       200       210        

         340       350       360       370
pF1KA0 AKNSWFSKTLNSIKTATGTQPLQPAPVTQPPKEST
       :::::::::::::::::::::::::::::::::::
XP_016 AKNSWFSKTLNSIKTATGTQPLQPAPVTQPPKEST
      220       230       240       250   

>>NP_001230693 (OMIM: 609238) rab GTPase-activating prot  (253 aa)
 initn: 1503 init1: 1503 opt: 1504  Z-score: 823.6  bits: 160.5 E(85289): 3.9e-39
Smith-Waterman score: 1504; 98.4% identity (98.8% similar) in 245 aa overlap (126-370:9-253)

         100       110       120       130       140       150     
pF1KA0 CNIKVPTKKLKKYEKEYQTMRESQLQQEDPMDRYKRENRRLQEASMRLEQENDDLAHELV
                                     :   .:::::::::::::::::::::::::
NP_001                       MIENSSWSMTFEERENRRLQEASMRLEQENDDLAHELV
                                     10        20        30        

         160       170       180       190       200       210     
pF1KA0 TSKIALRNDLDQAEDKADVLNKELLLTKQRLVETEEEKRKQEEETAQLKEVFRKQLEKAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSKIALRNDLDQAEDKADVLNKELLLTKQRLVETEEEKRKQEEETAQLKEVFRKQLEKAE
       40        50        60        70        80        90        

         220       230       240       250       260       270     
pF1KA0 YEIKKTTAIIAEYKQICSQLSTRLEKQQAASKEELEVVKGKMMACKHCSDIFSKEGALKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YEIKKTTAIIAEYKQICSQLSTRLEKQQAASKEELEVVKGKMMACKHCSDIFSKEGALKL
      100       110       120       130       140       150        

         280       290       300       310       320       330     
pF1KA0 AATGREDQGIETDDEKDSLKKQLREMELELAQTKLQLVEAKCKIQELEHQRGALMNEIQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AATGREDQGIETDDEKDSLKKQLREMELELAQTKLQLVEAKCKIQELEHQRGALMNEIQA
      160       170       180       190       200       210        

         340       350       360       370
pF1KA0 AKNSWFSKTLNSIKTATGTQPLQPAPVTQPPKEST
       :::::::::::::::::::::::::::::::::::
NP_001 AKNSWFSKTLNSIKTATGTQPLQPAPVTQPPKEST
      220       230       240       250   

>>XP_016870059 (OMIM: 615882) PREDICTED: rab GTPase-acti  (900 aa)
 initn: 1448 init1: 1384 opt: 1384  Z-score: 753.7  bits: 149.4 E(85289): 3e-35
Smith-Waterman score: 1384; 69.5% identity (91.1% similar) in 302 aa overlap (54-355:594-895)

            30        40        50        60        70        80   
pF1KA0 MHDERSKLVNEYACRVLELLGMGHRLFVPRLLATSKEDLLQADFEGALKFFRVQLPKRYR
                                     :: :::.::: .::::::::::::::::::
XP_016 TAKFPLYMVFHIIDLLLCEGISVIFNVALGLLKTSKDDLLLTDFEGALKFFRVQLPKRYR
           570       580       590       600       610       620   

            90       100       110       120       130       140   
pF1KA0 AEENARRLMEQACNIKVPTKKLKKYEKEYQTMRESQLQQEDPMDRYKRENRRLQEASMRL
       .::::..::: :::.:.  ::::::::::.::::.: :::::..:..:::::::::.:::
XP_016 SEENAKKLMELACNMKISQKKLKKYEKEYHTMREQQAQQEDPIERFERENRRLQEANMRL
           630       640       650       660       670       680   

           150       160       170       180       190       200   
pF1KA0 EQENDDLAHELVTSKIALRNDLDQAEDKADVLNKELLLTKQRLVETEEEKRKQEEETAQL
       :::::::::::::::::::.:::.::.:::.::::::.:::.:...:::::. :::.:::
XP_016 EQENDDLAHELVTSKIALRKDLDNAEEKADALNKELLMTKQKLIDAEEEKRRLEEESAQL
           690       700       710       720       730       740   

           210       220       230       240       250       260   
pF1KA0 KEVFRKQLEKAEYEIKKTTAIIAEYKQICSQLSTRLEKQQAASKEELEVVKGKMMACKHC
       ::. :..:.::: ::::...::..::::::::: ::::::.:.: :.: .. :.  :..:
XP_016 KEMCRRELDKAESEIKKNSSIIGDYKQICSQLSERLEKQQTANKVEIEKIRQKVDDCERC
           750       760       770       780       790       800   

           270       280       290       300       310       320   
pF1KA0 SDIFSKEGALKLAATGREDQGIETDDEKDSLKKQLREMELELAQTKLQLVEAKCKIQELE
        ..:.::: .:  .. .:    .::.::..::.:::::::::::::::::::.::::.::
XP_016 REFFNKEGRVKGISSTKEVLDEDTDEEKETLKNQLREMELELAQTKLQLVEAECKIQDLE
           810       820       830       840       850       860   

           330       340       350       360       370
pF1KA0 HQRGALMNEIQAAKNSWFSKTLNSIKTATGTQPLQPAPVTQPPKEST
       :. :  .::.::::..::..::.:::::::.:               
XP_016 HHLGLALNEVQAAKKTWFNRTLSSIKTATGVQGKETC          
           870       880       890       900          




370 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Wed Nov  2 19:01:58 2016 done: Wed Nov  2 19:01:59 2016
 Total Scan time:  7.910 Total Display time:  0.020

Function used was FASTA [36.3.4 Apr, 2011]
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