Result of FASTA (omim) for pF1KA0369
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KA0369, 729 aa
  1>>>pF1KA0369 729 - 729 aa - 729 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 11.6550+/-0.000595; mu= -8.2884+/- 0.037
 mean_var=590.9469+/-129.538, 0's: 0 Z-trim(118.3): 1790  B-trim: 0 in 0/56
 Lambda= 0.052759
 statistics sampled from 28775 (31130) to 28775 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.689), E-opt: 0.2 (0.365), width:  16
 Scan time: 12.430

The best scores are:                                      opt bits E(85289)
NP_004725 (OMIM: 604742) serine/threonine-protein  ( 729) 4795 381.1 8.8e-105
NP_001317000 (OMIM: 604742) serine/threonine-prote ( 740) 4490 357.9 8.6e-98
NP_001317001 (OMIM: 604742) serine/threonine-prote ( 740) 4490 357.9 8.6e-98
XP_016876336 (OMIM: 604742) PREDICTED: serine/thre ( 708) 4489 357.8 8.9e-98
NP_001182344 (OMIM: 604742) serine/threonine-prote ( 422) 2768 226.5 1.8e-58
XP_005262842 (OMIM: 613166) PREDICTED: serine/thre ( 782) 2497 206.2 4.1e-52
NP_001035350 (OMIM: 613166) serine/threonine-prote ( 766) 2485 205.3 7.7e-52
NP_001182345 (OMIM: 604742) serine/threonine-prote ( 433) 2463 203.3 1.7e-51
XP_005262843 (OMIM: 613166) PREDICTED: serine/thre ( 765) 2434 201.4 1.1e-50
NP_001035351 (OMIM: 613166) serine/threonine-prote ( 783) 2433 201.3 1.2e-50
XP_016863321 (OMIM: 613166) PREDICTED: serine/thre ( 717) 2419 200.2 2.4e-50
XP_016876337 (OMIM: 604742) PREDICTED: serine/thre ( 363) 2250 187.0 1.2e-46
NP_000546 (OMIM: 300067,300121) neuronal migration ( 441) 1689 144.4 9.5e-34
NP_835364 (OMIM: 300067,300121) neuronal migration ( 360) 1678 143.4 1.5e-33
NP_835366 (OMIM: 300067,300121) neuronal migration ( 360) 1678 143.4 1.5e-33
XP_011529180 (OMIM: 300067,300121) PREDICTED: neur ( 361) 1678 143.4 1.5e-33
NP_835365 (OMIM: 300067,300121) neuronal migration ( 365) 1674 143.1 1.9e-33
NP_001182482 (OMIM: 300067,300121) neuronal migrat ( 366) 1674 143.1 1.9e-33
XP_016884801 (OMIM: 300067,300121) PREDICTED: neur ( 366) 1674 143.1 1.9e-33
XP_011529182 (OMIM: 300067,300121) PREDICTED: neur ( 319) 1552 133.8 1.1e-30
XP_011529181 (OMIM: 300067,300121) PREDICTED: neur ( 324) 1551 133.7 1.1e-30
NP_208382 (OMIM: 613167) serine/threonine-protein  ( 648) 1063 96.9 2.7e-19
XP_011532469 (OMIM: 613167) PREDICTED: serine/thre ( 648) 1063 96.9 2.7e-19
XP_011529410 (OMIM: 300680) PREDICTED: calcium/cal ( 361)  854 80.7 1.1e-14
XP_011529409 (OMIM: 300680) PREDICTED: calcium/cal ( 343)  851 80.4 1.3e-14
XP_011529412 (OMIM: 300680) PREDICTED: calcium/cal ( 343)  851 80.4 1.3e-14
XP_006724872 (OMIM: 300680) PREDICTED: calcium/cal ( 343)  851 80.4 1.3e-14
XP_011529414 (OMIM: 300680) PREDICTED: calcium/cal ( 343)  851 80.4 1.3e-14
XP_016884767 (OMIM: 300680) PREDICTED: calcium/cal ( 343)  851 80.4 1.3e-14
XP_016884768 (OMIM: 300680) PREDICTED: calcium/cal ( 343)  851 80.4 1.3e-14
XP_011529413 (OMIM: 300680) PREDICTED: calcium/cal ( 343)  851 80.4 1.3e-14
XP_005274708 (OMIM: 300680) PREDICTED: calcium/cal ( 343)  851 80.4 1.3e-14
NP_001129212 (OMIM: 300680) calcium/calmodulin-dep ( 360)  851 80.5 1.3e-14
NP_003647 (OMIM: 604998) calcium/calmodulin-depend ( 370)  850 80.4 1.4e-14
XP_016884766 (OMIM: 300680) PREDICTED: calcium/cal ( 426)  851 80.6 1.5e-14
NP_001034671 (OMIM: 300680) calcium/calmodulin-dep ( 426)  851 80.6 1.5e-14
XP_005265573 (OMIM: 604998) PREDICTED: calcium/cal ( 413)  850 80.5 1.5e-14
XP_006717545 (OMIM: 607957) PREDICTED: calcium/cal ( 362)  847 80.2 1.7e-14
XP_006717546 (OMIM: 607957) PREDICTED: calcium/cal ( 355)  841 79.7 2.2e-14
NP_065130 (OMIM: 607957) calcium/calmodulin-depend ( 357)  841 79.7 2.3e-14
XP_016863322 (OMIM: 613166) PREDICTED: serine/thre ( 694)  848 80.6 2.3e-14
NP_705718 (OMIM: 607957) calcium/calmodulin-depend ( 385)  841 79.7 2.4e-14
XP_006717544 (OMIM: 607957) PREDICTED: calcium/cal ( 366)  824 78.4 5.6e-14
XP_011517893 (OMIM: 607957) PREDICTED: calcium/cal ( 372)  824 78.4 5.7e-14
NP_001310303 (OMIM: 114080) calcium/calmodulin-dep ( 473)  790 76.0 3.9e-13
NP_001735 (OMIM: 114080) calcium/calmodulin-depend ( 473)  790 76.0 3.9e-13
NP_001310304 (OMIM: 114080) calcium/calmodulin-dep ( 473)  790 76.0 3.9e-13
XP_016862843 (OMIM: 604998) PREDICTED: calcium/cal ( 326)  761 73.6 1.4e-12
XP_005265574 (OMIM: 604998) PREDICTED: calcium/cal ( 369)  761 73.6 1.6e-12
XP_016857355 (OMIM: 614994) PREDICTED: calcium/cal ( 476)  761 73.8 1.8e-12


>>NP_004725 (OMIM: 604742) serine/threonine-protein kina  (729 aa)
 initn: 4795 init1: 4795 opt: 4795  Z-score: 2002.2  bits: 381.1 E(85289): 8.8e-105
Smith-Waterman score: 4795; 100.0% identity (100.0% similar) in 729 aa overlap (1-729:1-729)

               10        20        30        40        50        60
pF1KA0 MSFGRDMELEHFDERDKAQRYSRGSRVNGLPSPTHSAHCSFYRTRTLQTLSSEKKAKKVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MSFGRDMELEHFDERDKAQRYSRGSRVNGLPSPTHSAHCSFYRTRTLQTLSSEKKAKKVR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 FYRNGDRYFKGIVYAISPDRFRSFEALLADLTRTLSDNVNLPQGVRTIYTIDGLKKISSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 FYRNGDRYFKGIVYAISPDRFRSFEALLADLTRTLSDNVNLPQGVRTIYTIDGLKKISSL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 DQLVEGESYVCGSIEPFKKLEYTKNVNPNWSVNVKTTSASRAVSSLATAKGSPSEVRENK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DQLVEGESYVCGSIEPFKKLEYTKNVNPNWSVNVKTTSASRAVSSLATAKGSPSEVRENK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 DFIRPKLVTIIRSGVKPRKAVRILLNKKTAHSFEQVLTDITDAIKLDSGVVKRLYTLDGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DFIRPKLVTIIRSGVKPRKAVRILLNKKTAHSFEQVLTDITDAIKLDSGVVKRLYTLDGK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 QVMCLQDFFGDDDIFIACGPEKFRYQDDFLLDESECRVVKSTSYTKIASSSRRSTTKSPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QVMCLQDFFGDDDIFIACGPEKFRYQDDFLLDESECRVVKSTSYTKIASSSRRSTTKSPG
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 PSRRSKSPASTSSVNGTPGSQLSTPRSGKSPSPSPTSPGSLRKQRSSQHGGSSTSLASTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PSRRSKSPASTSSVNGTPGSQLSTPRSGKSPSPSPTSPGSLRKQRSSQHGGSSTSLASTK
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 VCSSMDENDGPGEEVSEEGFQIPATITERYKVGRTIGDGNFAVVKECVERSTAREYALKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VCSSMDENDGPGEEVSEEGFQIPATITERYKVGRTIGDGNFAVVKECVERSTAREYALKI
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 IKKSKCRGKEHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 IKKSKCRGKEHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITST
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 NKYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 NKYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIV
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 DGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQ
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 ILMGQVDFPSPYWDNVSDSAKELITMMLLVDVDQRFSAVQVLEHPWVNDDGLPENEHQLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ILMGQVDFPSPYWDNVSDSAKELITMMLLVDVDQRFSAVQVLEHPWVNDDGLPENEHQLS
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 VAGKIKKHFNTGPKPNSTAAGVSVIALDHGFTIKRSGSLDYYQQPGMYWIRPPLLIRRGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VAGKIKKHFNTGPKPNSTAAGVSVIALDHGFTIKRSGSLDYYQQPGMYWIRPPLLIRRGR
              670       680       690       700       710       720

                
pF1KA0 FSDEDATRM
       :::::::::
NP_004 FSDEDATRM
                

>>NP_001317000 (OMIM: 604742) serine/threonine-protein k  (740 aa)
 initn: 4489 init1: 4489 opt: 4490  Z-score: 1876.6  bits: 357.9 E(85289): 8.6e-98
Smith-Waterman score: 4490; 96.3% identity (97.0% similar) in 723 aa overlap (1-715:1-718)

               10        20        30        40        50        60
pF1KA0 MSFGRDMELEHFDERDKAQRYSRGSRVNGLPSPTHSAHCSFYRTRTLQTLSSEKKAKKVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSFGRDMELEHFDERDKAQRYSRGSRVNGLPSPTHSAHCSFYRTRTLQTLSSEKKAKKVR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 FYRNGDRYFKGIVYAISPDRFRSFEALLADLTRTLSDNVNLPQGVRTIYTIDGLKKISSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FYRNGDRYFKGIVYAISPDRFRSFEALLADLTRTLSDNVNLPQGVRTIYTIDGLKKISSL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 DQLVEGESYVCGSIEPFKKLEYTKNVNPNWSVNVKTTSASRAVSSLATAKGSPSEVRENK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DQLVEGESYVCGSIEPFKKLEYTKNVNPNWSVNVKTTSASRAVSSLATAKGSPSEVRENK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 DFIRPKLVTIIRSGVKPRKAVRILLNKKTAHSFEQVLTDITDAIKLDSGVVKRLYTLDGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DFIRPKLVTIIRSGVKPRKAVRILLNKKTAHSFEQVLTDITDAIKLDSGVVKRLYTLDGK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 QVMCLQDFFGDDDIFIACGPEKFRYQDDFLLDESECRVVKSTSYTKIASSSRRSTTKSPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QVMCLQDFFGDDDIFIACGPEKFRYQDDFLLDESECRVVKSTSYTKIASSSRRSTTKSPG
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 PSRRSKSPASTSSVNGTPGSQLSTPRSGKSPSPSPTSPGSLRKQRSSQHGGSSTSLASTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSRRSKSPASTSSVNGTPGSQLSTPRSGKSPSPSPTSPGSLRKQRSSQHGGSSTSLASTK
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 VCSSMDENDGPGEEVSEEGFQIPATITERYKVGRTIGDGNFAVVKECVERSTAREYALKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VCSSMDENDGPGEEVSEEGFQIPATITERYKVGRTIGDGNFAVVKECVERSTAREYALKI
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 IKKSKCRGKEHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IKKSKCRGKEHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITST
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 NKYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NKYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIV
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 DGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQ
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 ILMGQVDFPSPYWDNVSDSAKELITMMLLVDVDQRFSAVQVLEHPWVNDDGLPENEHQLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILMGQVDFPSPYWDNVSDSAKELITMMLLVDVDQRFSAVQVLEHPWVNDDGLPENEHQLS
              610       620       630       640       650       660

              670       680          690        700           710  
pF1KA0 VAGKIKKHFNTGPKPNSTAAGVSVIA---LDHGFTI-KRSGSLD----YYQQPGMYWIRP
       ::::::::::::::::::::::::::   ::.   . .:  . :    :  ::.     :
NP_001 VAGKIKKHFNTGPKPNSTAAGVSVIATTALDKERQVFRRRRNQDVRSRYKAQPA-----P
              670       680       690       700       710          

            720                 
pF1KA0 PLLIRRGRFSDEDATRM        
       : :                      
NP_001 PELNSESEDYSPSSSETVRSPNSPF
         720       730       740

>>NP_001317001 (OMIM: 604742) serine/threonine-protein k  (740 aa)
 initn: 4489 init1: 4489 opt: 4490  Z-score: 1876.6  bits: 357.9 E(85289): 8.6e-98
Smith-Waterman score: 4490; 96.3% identity (97.0% similar) in 723 aa overlap (1-715:1-718)

               10        20        30        40        50        60
pF1KA0 MSFGRDMELEHFDERDKAQRYSRGSRVNGLPSPTHSAHCSFYRTRTLQTLSSEKKAKKVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSFGRDMELEHFDERDKAQRYSRGSRVNGLPSPTHSAHCSFYRTRTLQTLSSEKKAKKVR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 FYRNGDRYFKGIVYAISPDRFRSFEALLADLTRTLSDNVNLPQGVRTIYTIDGLKKISSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FYRNGDRYFKGIVYAISPDRFRSFEALLADLTRTLSDNVNLPQGVRTIYTIDGLKKISSL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 DQLVEGESYVCGSIEPFKKLEYTKNVNPNWSVNVKTTSASRAVSSLATAKGSPSEVRENK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DQLVEGESYVCGSIEPFKKLEYTKNVNPNWSVNVKTTSASRAVSSLATAKGSPSEVRENK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 DFIRPKLVTIIRSGVKPRKAVRILLNKKTAHSFEQVLTDITDAIKLDSGVVKRLYTLDGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DFIRPKLVTIIRSGVKPRKAVRILLNKKTAHSFEQVLTDITDAIKLDSGVVKRLYTLDGK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 QVMCLQDFFGDDDIFIACGPEKFRYQDDFLLDESECRVVKSTSYTKIASSSRRSTTKSPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QVMCLQDFFGDDDIFIACGPEKFRYQDDFLLDESECRVVKSTSYTKIASSSRRSTTKSPG
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 PSRRSKSPASTSSVNGTPGSQLSTPRSGKSPSPSPTSPGSLRKQRSSQHGGSSTSLASTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSRRSKSPASTSSVNGTPGSQLSTPRSGKSPSPSPTSPGSLRKQRSSQHGGSSTSLASTK
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 VCSSMDENDGPGEEVSEEGFQIPATITERYKVGRTIGDGNFAVVKECVERSTAREYALKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VCSSMDENDGPGEEVSEEGFQIPATITERYKVGRTIGDGNFAVVKECVERSTAREYALKI
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 IKKSKCRGKEHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IKKSKCRGKEHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITST
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 NKYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NKYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIV
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 DGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQ
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 ILMGQVDFPSPYWDNVSDSAKELITMMLLVDVDQRFSAVQVLEHPWVNDDGLPENEHQLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILMGQVDFPSPYWDNVSDSAKELITMMLLVDVDQRFSAVQVLEHPWVNDDGLPENEHQLS
              610       620       630       640       650       660

              670       680          690        700           710  
pF1KA0 VAGKIKKHFNTGPKPNSTAAGVSVIA---LDHGFTI-KRSGSLD----YYQQPGMYWIRP
       ::::::::::::::::::::::::::   ::.   . .:  . :    :  ::.     :
NP_001 VAGKIKKHFNTGPKPNSTAAGVSVIATTALDKERQVFRRRRNQDVRSRYKAQPA-----P
              670       680       690       700       710          

            720                 
pF1KA0 PLLIRRGRFSDEDATRM        
       : :                      
NP_001 PELNSESEDYSPSSSETVRSPNSPF
         720       730       740

>>XP_016876336 (OMIM: 604742) PREDICTED: serine/threonin  (708 aa)
 initn: 4605 init1: 4489 opt: 4489  Z-score: 1876.4  bits: 357.8 E(85289): 8.9e-98
Smith-Waterman score: 4566; 96.8% identity (97.0% similar) in 729 aa overlap (1-729:1-708)

               10        20        30        40        50        60
pF1KA0 MSFGRDMELEHFDERDKAQRYSRGSRVNGLPSPTHSAHCSFYRTRTLQTLSSEKKAKKVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSFGRDMELEHFDERDKAQRYSRGSRVNGLPSPTHSAHCSFYRTRTLQTLSSEKKAKKVR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 FYRNGDRYFKGIVYAISPDRFRSFEALLADLTRTLSDNVNLPQGVRTIYTIDGLKKISSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FYRNGDRYFKGIVYAISPDRFRSFEALLADLTRTLSDNVNLPQGVRTIYTIDGLKKISSL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 DQLVEGESYVCGSIEPFKKLEYTKNVNPNWSVNVKTTSASRAVSSLATAKGSPSEVRENK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DQLVEGESYVCGSIEPFKKLEYTKNVNPNWSVNVKTTSASRAVSSLATAKGSPSEVRENK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 DFIRPKLVTIIRSGVKPRKAVRILLNKKTAHSFEQVLTDITDAIKLDSGVVKRLYTLDGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DFIRPKLVTIIRSGVKPRKAVRILLNKKTAHSFEQVLTDITDAIKLDSGVVKRLYTLDGK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 QVMCLQDFFGDDDIFIACGPEKFRYQDDFLLDESECRVVKSTSYTKIASSSRRSTTKSPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QVMCLQDFFGDDDIFIACGPEKFRYQDDFLLDESECRVVKSTSYTKIASSSRRSTTKSPG
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 PSRRSKSPASTSSVNGTPGSQLSTPRSGKSPSPSPTSPGSLRKQRSSQHGGSSTSLASTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSRRSKSPASTSSVNGTPGSQLSTPRSGKSPSPSPTSPGSLRKQRSSQHGGSSTSLASTK
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 VCSSMDENDGPGEEVSEEGFQIPATITERYKVGRTIGDGNFAVVKECVERSTAREYALKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VCSSMDENDGPGEEVSEEGFQIPATITERYKVGRTIGDGNFAVVKECVERSTAREYALKI
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 IKKSKCRGKEHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IKKSKCRGKEHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITST
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 NKYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIV
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 DGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQ
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 ILMGQVDFPSPYWDNVSDSAKELITMMLLVDVDQRFSAVQVLEHPWVNDDGLPENEHQLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILMGQVDFPSPYWDNVSDSAKELITMMLLVDVDQRFSAVQVLEHPWVNDDGLPENEHQLS
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 VAGKIKKHFNTGPKPNSTAAGVSVIALDHGFTIKRSGSLDYYQQPGMYWIRPPLLIRRGR
       ::::::::::::::::::::::::::                  :.    ::::::::::
XP_016 VAGKIKKHFNTGPKPNSTAAGVSVIA-----------------APA----RPPLLIRRGR
              670       680                            690         

                
pF1KA0 FSDEDATRM
       :::::::::
XP_016 FSDEDATRM
     700        

>>NP_001182344 (OMIM: 604742) serine/threonine-protein k  (422 aa)
 initn: 2768 init1: 2768 opt: 2768  Z-score: 1170.9  bits: 226.5 E(85289): 1.8e-58
Smith-Waterman score: 2768; 100.0% identity (100.0% similar) in 416 aa overlap (314-729:7-422)

           290       300       310       320       330       340   
pF1KA0 YTKIASSSRRSTTKSPGPSRRSKSPASTSSVNGTPGSQLSTPRSGKSPSPSPTSPGSLRK
                                     ::::::::::::::::::::::::::::::
NP_001                         MLELIEVNGTPGSQLSTPRSGKSPSPSPTSPGSLRK
                                       10        20        30      

           350       360       370       380       390       400   
pF1KA0 QRSSQHGGSSTSLASTKVCSSMDENDGPGEEVSEEGFQIPATITERYKVGRTIGDGNFAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QRSSQHGGSSTSLASTKVCSSMDENDGPGEEVSEEGFQIPATITERYKVGRTIGDGNFAV
         40        50        60        70        80        90      

           410       420       430       440       450       460   
pF1KA0 VKECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VKECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYL
        100       110       120       130       140       150      

           470       480       490       500       510       520   
pF1KA0 VMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQ
        160       170       180       190       200       210      

           530       540       550       560       570       580   
pF1KA0 DGSKSLKLGDFGLATIVDGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGSKSLKLGDFGLATIVDGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCG
        220       230       240       250       260       270      

           590       600       610       620       630       640   
pF1KA0 FPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELITMMLLVDVDQRFSAVQVLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELITMMLLVDVDQRFSAVQVLE
        280       290       300       310       320       330      

           650       660       670       680       690       700   
pF1KA0 HPWVNDDGLPENEHQLSVAGKIKKHFNTGPKPNSTAAGVSVIALDHGFTIKRSGSLDYYQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HPWVNDDGLPENEHQLSVAGKIKKHFNTGPKPNSTAAGVSVIALDHGFTIKRSGSLDYYQ
        340       350       360       370       380       390      

           710       720         
pF1KA0 QPGMYWIRPPLLIRRGRFSDEDATRM
       ::::::::::::::::::::::::::
NP_001 QPGMYWIRPPLLIRRGRFSDEDATRM
        400       410       420  

>>XP_005262842 (OMIM: 613166) PREDICTED: serine/threonin  (782 aa)
 initn: 2936 init1: 1483 opt: 2497  Z-score: 1056.5  bits: 206.2 E(85289): 4.1e-52
Smith-Waterman score: 3185; 67.7% identity (83.9% similar) in 746 aa overlap (1-712:1-736)

               10        20                      30         40     
pF1KA0 MSFGRDMELEHFDERDKAQR--------------YSRGSRVNGL-PSPTHSAHCSFYRTR
       :.  :..:::::.::::  :               : : . ::: :::.:::::::::::
XP_005 MASTRSIELEHFEERDKRPRPGSRRGAPSSSGGSSSSGPKGNGLIPSPAHSAHCSFYRTR
               10        20        30        40        50        60

          50        60        70        80        90       100     
pF1KA0 TLQTLSSEKKAKKVRFYRNGDRYFKGIVYAISPDRFRSFEALLADLTRTLSDNVNLPQGV
       :::.:::::::::.::::::::::::.:.::: ::::::.::: .:::.:::::::::::
XP_005 TLQALSSEKKAKKARFYRNGDRYFKGLVFAISSDRFRSFDALLIELTRSLSDNVNLPQGV
               70        80        90       100       110       120

         110       120       130       140       150       160     
pF1KA0 RTIYTIDGLKKISSLDQLVEGESYVCGSIEPFKKLEYTKNVNPNWSVNVKTTSASRAVSS
       :::::::: .:..:::.:.:::::::.: :::.:..::::.:::::::.:  ..:::   
XP_005 RTIYTIDGSRKVTSLDELLEGESYVCASNEPFRKVDYTKNINPNWSVNIKG-GTSRA---
              130       140       150       160       170          

         170       180       190       200       210       220     
pF1KA0 LATAKGSPSEVRENKDFIRPKLVTIIRSGVKPRKAVRILLNKKTAHSFEQVLTDITDAIK
       ::.:..  :::.:.::::.:::::.:::::::::::::::::::::::::::::::.:::
XP_005 LAAASSVKSEVKESKDFIKPKLVTVIRSGVKPRKAVRILLNKKTAHSFEQVLTDITEAIK
        180       190       200       210       220       230      

         230       240       250       260        270       280    
pF1KA0 LDSGVVKRLYTLDGKQVMCLQDFFGDDDIFIACGPEKFRY-QDDFLLDESECRVVKSTSY
       ::::::::: ::::::: ::::::::::.::::::::::: ::::.::.:::::.:: ::
XP_005 LDSGVVKRLCTLDGKQVTCLQDFFGDDDVFIACGPEKFRYAQDDFVLDHSECRVLKS-SY
        240       250       260       270       280       290      

          290       300       310                     320       330
pF1KA0 TKIASSSRRSTTKSPGPSRRSKSPAST--------------SSVNGTPGSQLSTPRSGKS
       .. .:. . : .::::::::::::::.              : :::::.::::::.: ::
XP_005 SR-SSAVKYSGSKSPGPSRRSKSPASVKRGGHYSSAYSTAKSPVNGTPSSQLSTPKSTKS
          300       310       320       330       340       350    

              340       350       360       370       380       390
pF1KA0 PSPSPTSPGSLRKQRSSQHGGSSTSLASTKVCSSMDENDGPGEEVSEEGFQIPATITERY
        : :::::::.:  . : :: ::... .      .:.  .: : :. .  .  .:. :.:
XP_005 SSSSPTSPGSFRGLKISAHGRSSSNVNGGP---ELDRCISP-EGVNGNRCSESSTLLEKY
          360       370       380          390        400       410

              400       410       420       430       440       450
pF1KA0 KVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPNIVL
       :.:..::::::::::::..:::..:.::::: :.:: ::::.:.::::::::::::::..
XP_005 KIGKVIGDGNFAVVKECIDRSTGKEFALKIIDKAKCCGKEHLIENEVSILRRVKHPNIIM
              420       430       440       450       460       470

              460       470       480       490       500       510
pF1KA0 LIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVHR
       :.:::.. :::.:::::::::::::::::..::::::.:.:.::::.:..:::.:.::::
XP_005 LVEEMETATELFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLHGLSIVHR
              480       490       500       510       520       530

              520       530       540       550       560       570
pF1KA0 DIKPENLLVYEHQDGSKSLKLGDFGLATIVDGPLYTVCGTPTYVAPEIIAETGYGLKVDI
       ::::::::: :. ::.::::::::::::.:.:::::::::::::::::::::::::::::
XP_005 DIKPENLLVCEYPDGTKSLKLGDFGLATVVEGPLYTVCGTPTYVAPEIIAETGYGLKVDI
              540       550       560       570       580       590

              580       590       600       610       620       630
pF1KA0 WAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELITMMLLV
       ::::::::::::::::::. .. :: :::::: :...::.:::::..:::::::..:: :
XP_005 WAAGVITYILLCGFPPFRSENNLQEDLFDQILAGKLEFPAPYWDNITDSAKELISQMLQV
              600       610       620       630       640       650

              640       650       660       670        680         
pF1KA0 DVDQRFSAVQVLEHPWVNDDGLPENEHQLSVAGKIKKHFNTG-PKPNSTAAGVSVI---A
       .:. : .: :.: ::::.::.  ::. :  :.::.:.:::.. :: :::..:::::   :
XP_005 NVEARCTAGQILSHPWVSDDASQENNMQAEVTGKLKQHFNNALPKQNSTTTGVSVIMNTA
              660       670       680       690       700       710

        690       700       710       720                          
pF1KA0 LDHGFTIKRSGSLDYYQQPGMYWIRPPLLIRRGRFSDEDATRM                 
       ::.   :  :   .   .:::  : :                                  
XP_005 LDKEGQIFCSKHCQDSGRPGMEPISPVPPSVEEIPVPGEAVPAPTPPESPTPHPPPAAPG
              720       730       740       750       760       770

>>NP_001035350 (OMIM: 613166) serine/threonine-protein k  (766 aa)
 initn: 2255 init1: 1497 opt: 2485  Z-score: 1051.7  bits: 205.3 E(85289): 7.7e-52
Smith-Waterman score: 3194; 68.8% identity (85.3% similar) in 733 aa overlap (1-712:1-720)

               10        20                      30         40     
pF1KA0 MSFGRDMELEHFDERDKAQR--------------YSRGSRVNGL-PSPTHSAHCSFYRTR
       :.  :..:::::.::::  :               : : . ::: :::.:::::::::::
NP_001 MASTRSIELEHFEERDKRPRPGSRRGAPSSSGGSSSSGPKGNGLIPSPAHSAHCSFYRTR
               10        20        30        40        50        60

          50        60        70        80        90       100     
pF1KA0 TLQTLSSEKKAKKVRFYRNGDRYFKGIVYAISPDRFRSFEALLADLTRTLSDNVNLPQGV
       :::.:::::::::.::::::::::::.:.::: ::::::.::: .:::.:::::::::::
NP_001 TLQALSSEKKAKKARFYRNGDRYFKGLVFAISSDRFRSFDALLIELTRSLSDNVNLPQGV
               70        80        90       100       110       120

         110       120       130       140       150       160     
pF1KA0 RTIYTIDGLKKISSLDQLVEGESYVCGSIEPFKKLEYTKNVNPNWSVNVKTTSASRAVSS
       :::::::: .:..:::.:.:::::::.: :::.:..::::.:::::::.:  ..:::   
NP_001 RTIYTIDGSRKVTSLDELLEGESYVCASNEPFRKVDYTKNINPNWSVNIKG-GTSRA---
              130       140       150       160       170          

         170       180       190       200       210       220     
pF1KA0 LATAKGSPSEVRENKDFIRPKLVTIIRSGVKPRKAVRILLNKKTAHSFEQVLTDITDAIK
       ::.:..  :::.:.::::.:::::.:::::::::::::::::::::::::::::::.:::
NP_001 LAAASSVKSEVKESKDFIKPKLVTVIRSGVKPRKAVRILLNKKTAHSFEQVLTDITEAIK
        180       190       200       210       220       230      

         230       240       250       260        270       280    
pF1KA0 LDSGVVKRLYTLDGKQVMCLQDFFGDDDIFIACGPEKFRY-QDDFLLDESECRVVKSTSY
       ::::::::: ::::::: ::::::::::.::::::::::: ::::.::.:::::.:: ::
NP_001 LDSGVVKRLCTLDGKQVTCLQDFFGDDDVFIACGPEKFRYAQDDFVLDHSECRVLKS-SY
        240       250       260       270       280       290      

          290       300       310       320       330       340    
pF1KA0 TKIASSSRRSTTKSPGPSRRSKSPASTSSVNGTPGSQLSTPRSGKSPSPSPTSPGSLRKQ
       .. .:. . : .::::::::::::::   :::::.::::::.: :: : :::::::.:  
NP_001 SR-SSAVKYSGSKSPGPSRRSKSPAS---VNGTPSSQLSTPKSTKSSSSSPTSPGSFRGL
          300       310       320          330       340       350 

           350       360       370       380       390       400   
pF1KA0 RS-SQHGGSSTSLASTKVCSSMDENDGPGEEVSEEGFQIPATITERYKVGRTIGDGNFAV
       .. : :: ::... .      .:.  .: : :. .  .  .:. :.::.:..::::::::
NP_001 KQISAHGRSSSNVNGGP---ELDRCISP-EGVNGNRCSESSTLLEKYKIGKVIGDGNFAV
             360          370        380       390       400       

           410       420       430       440       450       460   
pF1KA0 VKECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYL
       ::::..:::..:.::::: :.:: ::::.:.::::::::::::::..:.:::.. :::.:
NP_001 VKECIDRSTGKEFALKIIDKAKCCGKEHLIENEVSILRRVKHPNIIMLVEEMETATELFL
       410       420       430       440       450       460       

           470       480       490       500       510       520   
pF1KA0 VMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQ
       ::::::::::::::::..::::::.:.:.::::.:..:::.:.::::::::::::: :. 
NP_001 VMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLHGLSIVHRDIKPENLLVCEYP
       470       480       490       500       510       520       

           530       540       550       560       570       580   
pF1KA0 DGSKSLKLGDFGLATIVDGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCG
       ::.::::::::::::.:.::::::::::::::::::::::::::::::::::::::::::
NP_001 DGTKSLKLGDFGLATVVEGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCG
       530       540       550       560       570       580       

           590       600       610       620       630       640   
pF1KA0 FPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELITMMLLVDVDQRFSAVQVLE
       :::::. .. :: :::::: :...::.:::::..:::::::..:: :.:. : .: :.: 
NP_001 FPPFRSENNLQEDLFDQILAGKLEFPAPYWDNITDSAKELISQMLQVNVEARCTAGQILS
       590       600       610       620       630       640       

           650       660       670        680          690         
pF1KA0 HPWVNDDGLPENEHQLSVAGKIKKHFNTG-PKPNSTAAGVSVI---ALDHGFTIKRSGSL
       ::::.::.  ::. :  :.::.:.:::.. :: :::..:::::   :::.   :  :   
NP_001 HPWVSDDASQENNMQAEVTGKLKQHFNNALPKQNSTTTGVSVIMNTALDKEGQIFCSKHC
       650       660       670       680       690       700       

     700       710       720                                      
pF1KA0 DYYQQPGMYWIRPPLLIRRGRFSDEDATRM                             
       .   .:::  : :                                              
NP_001 QDSGRPGMEPISPVPPSVEEIPVPGEAVPAPTPPESPTPHPPPAAPGGERAGTWRRHRD
       710       720       730       740       750       760      

>>NP_001182345 (OMIM: 604742) serine/threonine-protein k  (433 aa)
 initn: 2462 init1: 2462 opt: 2463  Z-score: 1045.4  bits: 203.3 E(85289): 1.7e-51
Smith-Waterman score: 2463; 93.4% identity (94.6% similar) in 410 aa overlap (314-715:7-411)

           290       300       310       320       330       340   
pF1KA0 YTKIASSSRRSTTKSPGPSRRSKSPASTSSVNGTPGSQLSTPRSGKSPSPSPTSPGSLRK
                                     ::::::::::::::::::::::::::::::
NP_001                         MLELIEVNGTPGSQLSTPRSGKSPSPSPTSPGSLRK
                                       10        20        30      

           350       360       370       380       390       400   
pF1KA0 QRSSQHGGSSTSLASTKVCSSMDENDGPGEEVSEEGFQIPATITERYKVGRTIGDGNFAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QRSSQHGGSSTSLASTKVCSSMDENDGPGEEVSEEGFQIPATITERYKVGRTIGDGNFAV
         40        50        60        70        80        90      

           410       420       430       440       450       460   
pF1KA0 VKECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VKECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYL
        100       110       120       130       140       150      

           470       480       490       500       510       520   
pF1KA0 VMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQ
        160       170       180       190       200       210      

           530       540       550       560       570       580   
pF1KA0 DGSKSLKLGDFGLATIVDGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGSKSLKLGDFGLATIVDGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCG
        220       230       240       250       260       270      

           590       600       610       620       630       640   
pF1KA0 FPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELITMMLLVDVDQRFSAVQVLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELITMMLLVDVDQRFSAVQVLE
        280       290       300       310       320       330      

           650       660       670       680          690          
pF1KA0 HPWVNDDGLPENEHQLSVAGKIKKHFNTGPKPNSTAAGVSVIA---LDHGFTI-KRSGSL
       :::::::::::::::::::::::::::::::::::::::::::   ::.   . .:  . 
NP_001 HPWVNDDGLPENEHQLSVAGKIKKHFNTGPKPNSTAAGVSVIATTALDKERQVFRRRRNQ
        340       350       360       370       380       390      

     700           710       720                 
pF1KA0 D----YYQQPGMYWIRPPLLIRRGRFSDEDATRM        
       :    :  ::.     :: :                      
NP_001 DVRSRYKAQPA-----PPELNSESEDYSPSSSETVRSPNSPF
        400            410       420       430   

>>XP_005262843 (OMIM: 613166) PREDICTED: serine/threonin  (765 aa)
 initn: 2932 init1: 1483 opt: 2434  Z-score: 1030.7  bits: 201.4 E(85289): 1.1e-50
Smith-Waterman score: 3203; 68.9% identity (85.2% similar) in 732 aa overlap (1-712:1-719)

               10        20                      30         40     
pF1KA0 MSFGRDMELEHFDERDKAQR--------------YSRGSRVNGL-PSPTHSAHCSFYRTR
       :.  :..:::::.::::  :               : : . ::: :::.:::::::::::
XP_005 MASTRSIELEHFEERDKRPRPGSRRGAPSSSGGSSSSGPKGNGLIPSPAHSAHCSFYRTR
               10        20        30        40        50        60

          50        60        70        80        90       100     
pF1KA0 TLQTLSSEKKAKKVRFYRNGDRYFKGIVYAISPDRFRSFEALLADLTRTLSDNVNLPQGV
       :::.:::::::::.::::::::::::.:.::: ::::::.::: .:::.:::::::::::
XP_005 TLQALSSEKKAKKARFYRNGDRYFKGLVFAISSDRFRSFDALLIELTRSLSDNVNLPQGV
               70        80        90       100       110       120

         110       120       130       140       150       160     
pF1KA0 RTIYTIDGLKKISSLDQLVEGESYVCGSIEPFKKLEYTKNVNPNWSVNVKTTSASRAVSS
       :::::::: .:..:::.:.:::::::.: :::.:..::::.:::::::.:  ..:::   
XP_005 RTIYTIDGSRKVTSLDELLEGESYVCASNEPFRKVDYTKNINPNWSVNIKG-GTSRA---
              130       140       150       160       170          

         170       180       190       200       210       220     
pF1KA0 LATAKGSPSEVRENKDFIRPKLVTIIRSGVKPRKAVRILLNKKTAHSFEQVLTDITDAIK
       ::.:..  :::.:.::::.:::::.:::::::::::::::::::::::::::::::.:::
XP_005 LAAASSVKSEVKESKDFIKPKLVTVIRSGVKPRKAVRILLNKKTAHSFEQVLTDITEAIK
        180       190       200       210       220       230      

         230       240       250       260        270       280    
pF1KA0 LDSGVVKRLYTLDGKQVMCLQDFFGDDDIFIACGPEKFRY-QDDFLLDESECRVVKSTSY
       ::::::::: ::::::: ::::::::::.::::::::::: ::::.::.:::::.:: ::
XP_005 LDSGVVKRLCTLDGKQVTCLQDFFGDDDVFIACGPEKFRYAQDDFVLDHSECRVLKS-SY
        240       250       260       270       280       290      

          290       300       310       320       330       340    
pF1KA0 TKIASSSRRSTTKSPGPSRRSKSPASTSSVNGTPGSQLSTPRSGKSPSPSPTSPGSLRKQ
       .. .:. . : .::::::::::::::   :::::.::::::.: :: : :::::::.:  
XP_005 SR-SSAVKYSGSKSPGPSRRSKSPAS---VNGTPSSQLSTPKSTKSSSSSPTSPGSFRGL
          300       310       320          330       340       350 

          350       360       370       380       390       400    
pF1KA0 RSSQHGGSSTSLASTKVCSSMDENDGPGEEVSEEGFQIPATITERYKVGRTIGDGNFAVV
       . : :: ::... .      .:.  .: : :. .  .  .:. :.::.:..:::::::::
XP_005 KISAHGRSSSNVNGGP---ELDRCISP-EGVNGNRCSESSTLLEKYKIGKVIGDGNFAVV
             360          370        380       390       400       

          410       420       430       440       450       460    
pF1KA0 KECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYLV
       :::..:::..:.::::: :.:: ::::.:.::::::::::::::..:.:::.. :::.::
XP_005 KECIDRSTGKEFALKIIDKAKCCGKEHLIENEVSILRRVKHPNIIMLVEEMETATELFLV
       410       420       430       440       450       460       

          470       480       490       500       510       520    
pF1KA0 MELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQD
       :::::::::::::::..::::::.:.:.::::.:..:::.:.::::::::::::: :. :
XP_005 MELVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLHGLSIVHRDIKPENLLVCEYPD
       470       480       490       500       510       520       

          530       540       550       560       570       580    
pF1KA0 GSKSLKLGDFGLATIVDGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGF
       :.::::::::::::.:.:::::::::::::::::::::::::::::::::::::::::::
XP_005 GTKSLKLGDFGLATVVEGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGF
       530       540       550       560       570       580       

          590       600       610       620       630       640    
pF1KA0 PPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELITMMLLVDVDQRFSAVQVLEH
       ::::. .. :: :::::: :...::.:::::..:::::::..:: :.:. : .: :.: :
XP_005 PPFRSENNLQEDLFDQILAGKLEFPAPYWDNITDSAKELISQMLQVNVEARCTAGQILSH
       590       600       610       620       630       640       

          650       660       670        680          690       700
pF1KA0 PWVNDDGLPENEHQLSVAGKIKKHFNTG-PKPNSTAAGVSVI---ALDHGFTIKRSGSLD
       :::.::.  ::. :  :.::.:.:::.. :: :::..:::::   :::.   :  :   .
XP_005 PWVSDDASQENNMQAEVTGKLKQHFNNALPKQNSTTTGVSVIMNTALDKEGQIFCSKHCQ
       650       660       670       680       690       700       

              710       720                                      
pF1KA0 YYQQPGMYWIRPPLLIRRGRFSDEDATRM                             
          .:::  : :                                              
XP_005 DSGRPGMEPISPVPPSVEEIPVPGEAVPAPTPPESPTPHPPPAAPGGERAGTWRRHRD
       710       720       730       740       750       760     

>>NP_001035351 (OMIM: 613166) serine/threonine-protein k  (783 aa)
 initn: 2256 init1: 1498 opt: 2433  Z-score: 1030.2  bits: 201.3 E(85289): 1.2e-50
Smith-Waterman score: 3176; 67.6% identity (83.9% similar) in 747 aa overlap (1-712:1-737)

               10        20                      30         40     
pF1KA0 MSFGRDMELEHFDERDKAQR--------------YSRGSRVNGL-PSPTHSAHCSFYRTR
       :.  :..:::::.::::  :               : : . ::: :::.:::::::::::
NP_001 MASTRSIELEHFEERDKRPRPGSRRGAPSSSGGSSSSGPKGNGLIPSPAHSAHCSFYRTR
               10        20        30        40        50        60

          50        60        70        80        90       100     
pF1KA0 TLQTLSSEKKAKKVRFYRNGDRYFKGIVYAISPDRFRSFEALLADLTRTLSDNVNLPQGV
       :::.:::::::::.::::::::::::.:.::: ::::::.::: .:::.:::::::::::
NP_001 TLQALSSEKKAKKARFYRNGDRYFKGLVFAISSDRFRSFDALLIELTRSLSDNVNLPQGV
               70        80        90       100       110       120

         110       120       130       140       150       160     
pF1KA0 RTIYTIDGLKKISSLDQLVEGESYVCGSIEPFKKLEYTKNVNPNWSVNVKTTSASRAVSS
       :::::::: .:..:::.:.:::::::.: :::.:..::::.:::::::.:  ..:::   
NP_001 RTIYTIDGSRKVTSLDELLEGESYVCASNEPFRKVDYTKNINPNWSVNIKG-GTSRA---
              130       140       150       160       170          

         170       180       190       200       210       220     
pF1KA0 LATAKGSPSEVRENKDFIRPKLVTIIRSGVKPRKAVRILLNKKTAHSFEQVLTDITDAIK
       ::.:..  :::.:.::::.:::::.:::::::::::::::::::::::::::::::.:::
NP_001 LAAASSVKSEVKESKDFIKPKLVTVIRSGVKPRKAVRILLNKKTAHSFEQVLTDITEAIK
        180       190       200       210       220       230      

         230       240       250       260        270       280    
pF1KA0 LDSGVVKRLYTLDGKQVMCLQDFFGDDDIFIACGPEKFRY-QDDFLLDESECRVVKSTSY
       ::::::::: ::::::: ::::::::::.::::::::::: ::::.::.:::::.:: ::
NP_001 LDSGVVKRLCTLDGKQVTCLQDFFGDDDVFIACGPEKFRYAQDDFVLDHSECRVLKS-SY
        240       250       260       270       280       290      

          290       300       310                     320       330
pF1KA0 TKIASSSRRSTTKSPGPSRRSKSPAST--------------SSVNGTPGSQLSTPRSGKS
       .. .:. . : .::::::::::::::.              : :::::.::::::.: ::
NP_001 SR-SSAVKYSGSKSPGPSRRSKSPASVKRGGHYSSAYSTAKSPVNGTPSSQLSTPKSTKS
          300       310       320       330       340       350    

              340        350       360       370       380         
pF1KA0 PSPSPTSPGSLRKQRS-SQHGGSSTSLASTKVCSSMDENDGPGEEVSEEGFQIPATITER
        : :::::::.:  .. : :: ::... .      .:.  .: : :. .  .  .:. :.
NP_001 SSSSPTSPGSFRGLKQISAHGRSSSNVNGGP---ELDRCISP-EGVNGNRCSESSTLLEK
          360       370       380          390        400       410

     390       400       410       420       430       440         
pF1KA0 YKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPNIV
       ::.:..::::::::::::..:::..:.::::: :.:: ::::.:.::::::::::::::.
NP_001 YKIGKVIGDGNFAVVKECIDRSTGKEFALKIIDKAKCCGKEHLIENEVSILRRVKHPNII
              420       430       440       450       460       470

     450       460       470       480       490       500         
pF1KA0 LLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVH
       .:.:::.. :::.:::::::::::::::::..::::::.:.:.::::.:..:::.:.:::
NP_001 MLVEEMETATELFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLHGLSIVH
              480       490       500       510       520       530

     510       520       530       540       550       560         
pF1KA0 RDIKPENLLVYEHQDGSKSLKLGDFGLATIVDGPLYTVCGTPTYVAPEIIAETGYGLKVD
       :::::::::: :. ::.::::::::::::.:.::::::::::::::::::::::::::::
NP_001 RDIKPENLLVCEYPDGTKSLKLGDFGLATVVEGPLYTVCGTPTYVAPEIIAETGYGLKVD
              540       550       560       570       580       590

     570       580       590       600       610       620         
pF1KA0 IWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELITMMLL
       :::::::::::::::::::. .. :: :::::: :...::.:::::..:::::::..:: 
NP_001 IWAAGVITYILLCGFPPFRSENNLQEDLFDQILAGKLEFPAPYWDNITDSAKELISQMLQ
              600       610       620       630       640       650

     630       640       650       660       670        680        
pF1KA0 VDVDQRFSAVQVLEHPWVNDDGLPENEHQLSVAGKIKKHFNTG-PKPNSTAAGVSVI---
       :.:. : .: :.: ::::.::.  ::. :  :.::.:.:::.. :: :::..:::::   
NP_001 VNVEARCTAGQILSHPWVSDDASQENNMQAEVTGKLKQHFNNALPKQNSTTTGVSVIMNT
              660       670       680       690       700       710

         690       700       710       720                         
pF1KA0 ALDHGFTIKRSGSLDYYQQPGMYWIRPPLLIRRGRFSDEDATRM                
       :::.   :  :   .   .:::  : :                                 
NP_001 ALDKEGQIFCSKHCQDSGRPGMEPISPVPPSVEEIPVPGEAVPAPTPPESPTPHPPPAAP
              720       730       740       750       760       770




729 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Wed Nov  2 18:44:42 2016 done: Wed Nov  2 18:44:44 2016
 Total Scan time: 12.430 Total Display time:  0.160

Function used was FASTA [36.3.4 Apr, 2011]
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