Result of FASTA (omim) for pF1KA0148
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KA0148, 681 aa
  1>>>pF1KA0148 681 - 681 aa - 681 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 9.0678+/-0.000513; mu= 0.9740+/- 0.032
 mean_var=238.2631+/-49.927, 0's: 0 Z-trim(115.9): 173  B-trim: 352 in 2/48
 Lambda= 0.083089
 statistics sampled from 26509 (26724) to 26509 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.669), E-opt: 0.2 (0.313), width:  16
 Scan time:  8.930

The best scores are:                                      opt bits E(85289)
NP_001128685 (OMIM: 608564) ARF GTPase-activating  ( 681) 4522 556.2 1.5e-157
NP_055591 (OMIM: 608564) ARF GTPase-activating pro ( 679) 4488 552.1 2.5e-156
XP_006719772 (OMIM: 608564) PREDICTED: ARF GTPase- ( 709) 3301 409.8 1.7e-113
NP_001317082 (OMIM: 608564) ARF GTPase-activating  ( 708) 3300 409.7 1.9e-113
XP_006719775 (OMIM: 608564) PREDICTED: ARF GTPase- ( 596) 2759 344.8 5.5e-94
NP_476511 (OMIM: 608564) ARF GTPase-activating pro ( 631) 2754 344.2 8.8e-94
NP_001317083 (OMIM: 608564) ARF GTPase-activating  ( 421) 2746 343.1 1.3e-93
XP_006719776 (OMIM: 608564) PREDICTED: ARF GTPase- ( 456) 2744 342.9 1.6e-93
NP_631940 (OMIM: 608564) ARF GTPase-activating pro ( 471) 2744 342.9 1.6e-93
XP_016875750 (OMIM: 608564) PREDICTED: ARF GTPase- ( 470) 2743 342.8 1.7e-93
XP_006719771 (OMIM: 608564) PREDICTED: ARF GTPase- ( 714) 2746 343.3 1.9e-93
XP_016875747 (OMIM: 608564) PREDICTED: ARF GTPase- ( 713) 2745 343.2   2e-93
XP_016875749 (OMIM: 608564) PREDICTED: ARF GTPase- ( 664) 2744 343.0 2.1e-93
XP_016875748 (OMIM: 608564) PREDICTED: ARF GTPase- ( 694) 2744 343.1 2.2e-93
NP_001128686 (OMIM: 608564) ARF GTPase-activating  ( 729) 2744 343.1 2.2e-93
XP_006719770 (OMIM: 608564) PREDICTED: ARF GTPase- ( 744) 2744 343.1 2.3e-93
NP_476510 (OMIM: 608564) ARF GTPase-activating pro ( 759) 2744 343.1 2.3e-93
XP_005254054 (OMIM: 608564) PREDICTED: ARF GTPase- ( 758) 2743 343.0 2.5e-93
NP_001078923 (OMIM: 608434) ARF GTPase-activating  ( 770) 2238 282.4 4.2e-75
XP_011522986 (OMIM: 608434) PREDICTED: ARF GTPase- ( 777) 2238 282.4 4.3e-75
NP_054749 (OMIM: 608434) ARF GTPase-activating pro ( 761) 2185 276.1 3.4e-73
XP_011522987 (OMIM: 608434) PREDICTED: ARF GTPase- ( 768) 2185 276.1 3.5e-73
XP_016867224 (OMIM: 616813) PREDICTED: arf-GAP wit ( 462)  333 53.9 1.6e-06
XP_016867222 (OMIM: 616813) PREDICTED: arf-GAP wit ( 527)  333 53.9 1.8e-06
XP_005250000 (OMIM: 616813) PREDICTED: arf-GAP wit ( 565)  333 54.0 1.9e-06
NP_001268229 (OMIM: 616813) arf-GAP with GTPase, A ( 580)  333 54.0 1.9e-06
XP_016867223 (OMIM: 616813) PREDICTED: arf-GAP wit ( 580)  333 54.0 1.9e-06
XP_016867221 (OMIM: 616813) PREDICTED: arf-GAP wit ( 630)  333 54.0   2e-06
XP_011514082 (OMIM: 616813) PREDICTED: arf-GAP wit ( 683)  333 54.0 2.1e-06
NP_114152 (OMIM: 616813) arf-GAP with GTPase, ANK  ( 911)  333 54.1 2.7e-06
NP_055729 (OMIM: 608651) arf-GAP with GTPase, ANK  ( 804)  317 52.2 9.1e-06
XP_005246116 (OMIM: 608651) PREDICTED: arf-GAP wit ( 808)  317 52.2 9.2e-06
NP_001032208 (OMIM: 608651) arf-GAP with GTPase, A ( 857)  317 52.2 9.6e-06
XP_006712298 (OMIM: 608651) PREDICTED: arf-GAP wit ( 882)  317 52.2 9.8e-06
XP_006712297 (OMIM: 608651) PREDICTED: arf-GAP wit ( 886)  317 52.2 9.8e-06
XP_011508851 (OMIM: 608651) PREDICTED: arf-GAP wit (1073)  317 52.3 1.1e-05
XP_011508850 (OMIM: 608651) PREDICTED: arf-GAP wit (1098)  317 52.3 1.2e-05
XP_016858771 (OMIM: 608651) PREDICTED: arf-GAP wit (1106)  317 52.3 1.2e-05
XP_011508849 (OMIM: 608651) PREDICTED: arf-GAP wit (1126)  317 52.3 1.2e-05
XP_006712300 (OMIM: 608651) PREDICTED: arf-GAP wit (1147)  317 52.3 1.2e-05
XP_006712302 (OMIM: 608651) PREDICTED: arf-GAP wit (1151)  317 52.3 1.2e-05
NP_055585 (OMIM: 605476) arf-GAP with GTPase, ANK  ( 836)  302 50.4 3.3e-05
XP_005268683 (OMIM: 605476) PREDICTED: arf-GAP wit ( 856)  302 50.4 3.3e-05
XP_005268682 (OMIM: 605476) PREDICTED: arf-GAP wit (1172)  302 50.5 4.2e-05
XP_016874261 (OMIM: 605476) PREDICTED: arf-GAP wit (1192)  302 50.5 4.3e-05
NP_001116244 (OMIM: 605476) arf-GAP with GTPase, A (1192)  302 50.5 4.3e-05
XP_011510907 (OMIM: 607766) PREDICTED: arf-GAP wit ( 776)  265 45.9 0.00067
XP_011510908 (OMIM: 607766) PREDICTED: arf-GAP wit ( 776)  265 45.9 0.00067
XP_011510906 (OMIM: 607766) PREDICTED: arf-GAP wit ( 776)  265 45.9 0.00067
NP_036419 (OMIM: 607766) arf-GAP with coiled-coil, ( 778)  265 45.9 0.00067


>>NP_001128685 (OMIM: 608564) ARF GTPase-activating prot  (681 aa)
 initn: 4522 init1: 4522 opt: 4522  Z-score: 2949.7  bits: 556.2 E(85289): 1.5e-157
Smith-Waterman score: 4522; 100.0% identity (100.0% similar) in 681 aa overlap (1-681:1-681)

               10        20        30        40        50        60
pF1KA0 MSKRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSKRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 LQMVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQMVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 PCRDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGNTPLHVASKAGQI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PCRDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGNTPLHVASKAGQI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 LQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVEIQYELTDRLAFYLCGRKPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVEIQYELTDRLAFYLCGRKPD
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 HKNGQHFIIPQMADRRLSLDLSELAKAAKKKLQSLSNHLFEELAMDVYDEVDRRETDAVW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HKNGQHFIIPQMADRRLSLDLSELAKAAKKKLQSLSNHLFEELAMDVYDEVDRRETDAVW
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 LATQNHSALVTETTVVPFLPVNPEYSSTRNQGRQKLARFNAHEFATLVIDILSDAKRRQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LATQNHSALVTETTVVPFLPVNPEYSSTRNQGRQKLARFNAHEFATLVIDILSDAKRRQQ
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 GSSLSGSKDNVELILKTINNQHSVESQDNDQPDYDSVASDEDTDLETTASKTNRQKLQTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSSLSGSKDNVELILKTINNQHSVESQDNDQPDYDSVASDEDTDLETTASKTNRQKLQTL
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 QSENSNLRKQATTNVYQVQTGSEYTDTSNHSSLKRRPSARGSRPMSMYETGSGQKPYLPM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSENSNLRKQATTNVYQVQTGSEYTDTSNHSSLKRRPSARGSRPMSMYETGSGQKPYLPM
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 GEASRPEESRMRLQPFPAHASRLEKQNSTPESDYDNTPNDMEPDGMGSSRKGRQRSMVWP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GEASRPEESRMRLQPFPAHASRLEKQNSTPESDYDNTPNDMEPDGMGSSRKGRQRSMVWP
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 GDGLVPDTAEPHVAPSPTLPSTEDVIRKTEQITKNIQELLRAAQENKHDSYIPCSERIHV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GDGLVPDTAEPHVAPSPTLPSTEDVIRKTEQITKNIQELLRAAQENKHDSYIPCSERIHV
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 AVTEMAALFPKKPKSDMVRTSLRLLTSSAYRLQSECKKTLPGDPGSPTDVQLVTQQVIQC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVTEMAALFPKKPKSDMVRTSLRLLTSSAYRLQSECKKTLPGDPGSPTDVQLVTQQVIQC
              610       620       630       640       650       660

              670       680 
pF1KA0 AYDIAKAAKQLVTITTKENNN
       :::::::::::::::::::::
NP_001 AYDIAKAAKQLVTITTKENNN
              670       680 

>>NP_055591 (OMIM: 608564) ARF GTPase-activating protein  (679 aa)
 initn: 2747 init1: 2747 opt: 4488  Z-score: 2927.6  bits: 552.1 E(85289): 2.5e-156
Smith-Waterman score: 4488; 99.6% identity (99.6% similar) in 681 aa overlap (1-681:1-679)

               10        20        30        40        50        60
pF1KA0 MSKRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MSKRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 LQMVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LQMVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 PCRDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGNTPLHVASKAGQI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PCRDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGNTPLHVASKAGQI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 LQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVEIQYELTDRLAFYLCGRKPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVEIQYELTDRLAFYLCGRKPD
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 HKNGQHFIIPQMADRRLSLDLSELAKAAKKKLQSLSNHLFEELAMDVYDEVDRRETDAVW
       ::::::::::::::   :::::::::::::::::::::::::::::::::::::::::::
NP_055 HKNGQHFIIPQMADS--SLDLSELAKAAKKKLQSLSNHLFEELAMDVYDEVDRRETDAVW
              250         260       270       280       290        

              310       320       330       340       350       360
pF1KA0 LATQNHSALVTETTVVPFLPVNPEYSSTRNQGRQKLARFNAHEFATLVIDILSDAKRRQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LATQNHSALVTETTVVPFLPVNPEYSSTRNQGRQKLARFNAHEFATLVIDILSDAKRRQQ
      300       310       320       330       340       350        

              370       380       390       400       410       420
pF1KA0 GSSLSGSKDNVELILKTINNQHSVESQDNDQPDYDSVASDEDTDLETTASKTNRQKLQTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GSSLSGSKDNVELILKTINNQHSVESQDNDQPDYDSVASDEDTDLETTASKTNRQKLQTL
      360       370       380       390       400       410        

              430       440       450       460       470       480
pF1KA0 QSENSNLRKQATTNVYQVQTGSEYTDTSNHSSLKRRPSARGSRPMSMYETGSGQKPYLPM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QSENSNLRKQATTNVYQVQTGSEYTDTSNHSSLKRRPSARGSRPMSMYETGSGQKPYLPM
      420       430       440       450       460       470        

              490       500       510       520       530       540
pF1KA0 GEASRPEESRMRLQPFPAHASRLEKQNSTPESDYDNTPNDMEPDGMGSSRKGRQRSMVWP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GEASRPEESRMRLQPFPAHASRLEKQNSTPESDYDNTPNDMEPDGMGSSRKGRQRSMVWP
      480       490       500       510       520       530        

              550       560       570       580       590       600
pF1KA0 GDGLVPDTAEPHVAPSPTLPSTEDVIRKTEQITKNIQELLRAAQENKHDSYIPCSERIHV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GDGLVPDTAEPHVAPSPTLPSTEDVIRKTEQITKNIQELLRAAQENKHDSYIPCSERIHV
      540       550       560       570       580       590        

              610       620       630       640       650       660
pF1KA0 AVTEMAALFPKKPKSDMVRTSLRLLTSSAYRLQSECKKTLPGDPGSPTDVQLVTQQVIQC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 AVTEMAALFPKKPKSDMVRTSLRLLTSSAYRLQSECKKTLPGDPGSPTDVQLVTQQVIQC
      600       610       620       630       640       650        

              670       680 
pF1KA0 AYDIAKAAKQLVTITTKENNN
       :::::::::::::::::::::
NP_055 AYDIAKAAKQLVTITTKENNN
      660       670         

>>XP_006719772 (OMIM: 608564) PREDICTED: ARF GTPase-acti  (709 aa)
 initn: 4489 init1: 1764 opt: 3301  Z-score: 2158.4  bits: 409.8 E(85289): 1.7e-113
Smith-Waterman score: 4418; 95.4% identity (95.4% similar) in 711 aa overlap (1-681:1-709)

               10        20        30        40        50        60
pF1KA0 MSKRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MSKRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 LQMVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LQMVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 PCRDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGNTPLHVASKAGQI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PCRDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGNTPLHVASKAGQI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 LQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVEIQYELTDRLAFYLCGRKPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVEIQYELTDRLAFYLCGRKPD
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 HKNGQHFIIPQMADRRLSLDLSELAKAAKKKLQSLSNHLFEELAMDVYDEVDRRETDAVW
       ::::::::::::::   :::::::::::::::::::::::::::::::::::::::::::
XP_006 HKNGQHFIIPQMADS--SLDLSELAKAAKKKLQSLSNHLFEELAMDVYDEVDRRETDAVW
              250         260       270       280       290        

              310       320       330       340       350       360
pF1KA0 LATQNHSALVTETTVVPFLPVNPEYSSTRNQGRQKLARFNAHEFATLVIDILSDAKRRQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LATQNHSALVTETTVVPFLPVNPEYSSTRNQGRQKLARFNAHEFATLVIDILSDAKRRQQ
      300       310       320       330       340       350        

              370       380       390       400       410       420
pF1KA0 GSSLSGSKDNVELILKTINNQHSVESQDNDQPDYDSVASDEDTDLETTASKTNRQKLQTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GSSLSGSKDNVELILKTINNQHSVESQDNDQPDYDSVASDEDTDLETTASKTNRQKLQTL
      360       370       380       390       400       410        

              430       440       450       460       470       480
pF1KA0 QSENSNLRKQATTNVYQVQTGSEYTDTSNHSSLKRRPSARGSRPMSMYETGSGQKPYLPM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QSENSNLRKQATTNVYQVQTGSEYTDTSNHSSLKRRPSARGSRPMSMYETGSGQKPYLPM
      420       430       440       450       460       470        

              490                                     500       510
pF1KA0 GEASRPEESRMRLQPFPAH------------------------------ASRLEKQNSTP
       :::::::::::::::::::                              :::::::::::
XP_006 GEASRPEESRMRLQPFPAHIGRSALVTSSSSLPSFPSTLSWSRDESARRASRLEKQNSTP
      480       490       500       510       520       530        

              520       530       540       550       560       570
pF1KA0 ESDYDNTPNDMEPDGMGSSRKGRQRSMVWPGDGLVPDTAEPHVAPSPTLPSTEDVIRKTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ESDYDNTPNDMEPDGMGSSRKGRQRSMVWPGDGLVPDTAEPHVAPSPTLPSTEDVIRKTE
      540       550       560       570       580       590        

              580       590       600       610       620       630
pF1KA0 QITKNIQELLRAAQENKHDSYIPCSERIHVAVTEMAALFPKKPKSDMVRTSLRLLTSSAY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QITKNIQELLRAAQENKHDSYIPCSERIHVAVTEMAALFPKKPKSDMVRTSLRLLTSSAY
      600       610       620       630       640       650        

              640       650       660       670       680 
pF1KA0 RLQSECKKTLPGDPGSPTDVQLVTQQVIQCAYDIAKAAKQLVTITTKENNN
       :::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RLQSECKKTLPGDPGSPTDVQLVTQQVIQCAYDIAKAAKQLVTITTKENNN
      660       670       680       690       700         

>>NP_001317082 (OMIM: 608564) ARF GTPase-activating prot  (708 aa)
 initn: 4488 init1: 1763 opt: 3300  Z-score: 2157.8  bits: 409.7 E(85289): 1.9e-113
Smith-Waterman score: 4417; 95.4% identity (95.4% similar) in 711 aa overlap (1-681:1-708)

               10        20        30        40        50        60
pF1KA0 MSKRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSKRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 LQMVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQMVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 PCRDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGNTPLHVASKAGQI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PCRDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGNTPLHVASKAGQI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 LQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVEIQYELTDRLAFYLCGRKPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVEIQYELTDRLAFYLCGRKPD
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 HKNGQHFIIPQMADRRLSLDLSELAKAAKKKLQSLSNHLFEELAMDVYDEVDRRETDAVW
       ::::::::::::::   :::::::::::::::::::::::::::::::::::::::::::
NP_001 HKNGQHFIIPQMAD---SLDLSELAKAAKKKLQSLSNHLFEELAMDVYDEVDRRETDAVW
              250          260       270       280       290       

              310       320       330       340       350       360
pF1KA0 LATQNHSALVTETTVVPFLPVNPEYSSTRNQGRQKLARFNAHEFATLVIDILSDAKRRQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LATQNHSALVTETTVVPFLPVNPEYSSTRNQGRQKLARFNAHEFATLVIDILSDAKRRQQ
       300       310       320       330       340       350       

              370       380       390       400       410       420
pF1KA0 GSSLSGSKDNVELILKTINNQHSVESQDNDQPDYDSVASDEDTDLETTASKTNRQKLQTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSSLSGSKDNVELILKTINNQHSVESQDNDQPDYDSVASDEDTDLETTASKTNRQKLQTL
       360       370       380       390       400       410       

              430       440       450       460       470       480
pF1KA0 QSENSNLRKQATTNVYQVQTGSEYTDTSNHSSLKRRPSARGSRPMSMYETGSGQKPYLPM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSENSNLRKQATTNVYQVQTGSEYTDTSNHSSLKRRPSARGSRPMSMYETGSGQKPYLPM
       420       430       440       450       460       470       

              490                                     500       510
pF1KA0 GEASRPEESRMRLQPFPAH------------------------------ASRLEKQNSTP
       :::::::::::::::::::                              :::::::::::
NP_001 GEASRPEESRMRLQPFPAHIGRSALVTSSSSLPSFPSTLSWSRDESARRASRLEKQNSTP
       480       490       500       510       520       530       

              520       530       540       550       560       570
pF1KA0 ESDYDNTPNDMEPDGMGSSRKGRQRSMVWPGDGLVPDTAEPHVAPSPTLPSTEDVIRKTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESDYDNTPNDMEPDGMGSSRKGRQRSMVWPGDGLVPDTAEPHVAPSPTLPSTEDVIRKTE
       540       550       560       570       580       590       

              580       590       600       610       620       630
pF1KA0 QITKNIQELLRAAQENKHDSYIPCSERIHVAVTEMAALFPKKPKSDMVRTSLRLLTSSAY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QITKNIQELLRAAQENKHDSYIPCSERIHVAVTEMAALFPKKPKSDMVRTSLRLLTSSAY
       600       610       620       630       640       650       

              640       650       660       670       680 
pF1KA0 RLQSECKKTLPGDPGSPTDVQLVTQQVIQCAYDIAKAAKQLVTITTKENNN
       :::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLQSECKKTLPGDPGSPTDVQLVTQQVIQCAYDIAKAAKQLVTITTKENNN
       660       670       680       690       700        

>>XP_006719775 (OMIM: 608564) PREDICTED: ARF GTPase-acti  (596 aa)
 initn: 2949 init1: 1764 opt: 2759  Z-score: 1808.3  bits: 344.8 E(85289): 5.5e-94
Smith-Waterman score: 3764; 87.4% identity (87.4% similar) in 681 aa overlap (1-681:1-596)

               10        20        30        40        50        60
pF1KA0 MSKRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MSKRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 LQMVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LQMVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 PCRDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGNTPLHVASKAGQI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PCRDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGNTPLHVASKAGQI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 LQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVEIQYELTDRLAFYLCGRKPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVEIQYELTDRLAFYLCGRKPD
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 HKNGQHFIIPQMADRRLSLDLSELAKAAKKKLQSLSNHLFEELAMDVYDEVDRRETDAVW
       ::::::::::::::   :::::::::::::::::::::::::::::::::::::::::::
XP_006 HKNGQHFIIPQMADS--SLDLSELAKAAKKKLQSLSNHLFEELAMDVYDEVDRRETDAVW
              250         260       270       280       290        

              310       320       330       340       350       360
pF1KA0 LATQNHSALVTETTVVPFLPVNPEYSSTRNQGRQKLARFNAHEFATLVIDILSDAKRRQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LATQNHSALVTETTVVPFLPVNPEYSSTRNQGRQKLARFNAHEFATLVIDILSDAKRRQQ
      300       310       320       330       340       350        

              370       380       390       400       410       420
pF1KA0 GSSLSGSKDNVELILKTINNQHSVESQDNDQPDYDSVASDEDTDLETTASKTNRQKLQTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::    
XP_006 GSSLSGSKDNVELILKTINNQHSVESQDNDQPDYDSVASDEDTDLETTASKTNRQK----
      360       370       380       390       400       410        

              430       440       450       460       470       480
pF1KA0 QSENSNLRKQATTNVYQVQTGSEYTDTSNHSSLKRRPSARGSRPMSMYETGSGQKPYLPM
                                                                   
XP_006 ------------------------------------------------------------
                                                                   

              490       500       510       520       530       540
pF1KA0 GEASRPEESRMRLQPFPAHASRLEKQNSTPESDYDNTPNDMEPDGMGSSRKGRQRSMVWP
                          :::::::::::::::::::::::::::::::::::::::::
XP_006 -------------------ASRLEKQNSTPESDYDNTPNDMEPDGMGSSRKGRQRSMVWP
                             420       430       440       450     

              550       560       570       580       590       600
pF1KA0 GDGLVPDTAEPHVAPSPTLPSTEDVIRKTEQITKNIQELLRAAQENKHDSYIPCSERIHV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GDGLVPDTAEPHVAPSPTLPSTEDVIRKTEQITKNIQELLRAAQENKHDSYIPCSERIHV
         460       470       480       490       500       510     

              610       620       630       640       650       660
pF1KA0 AVTEMAALFPKKPKSDMVRTSLRLLTSSAYRLQSECKKTLPGDPGSPTDVQLVTQQVIQC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AVTEMAALFPKKPKSDMVRTSLRLLTSSAYRLQSECKKTLPGDPGSPTDVQLVTQQVIQC
         520       530       540       550       560       570     

              670       680 
pF1KA0 AYDIAKAAKQLVTITTKENNN
       :::::::::::::::::::::
XP_006 AYDIAKAAKQLVTITTKENNN
         580       590      

>>NP_476511 (OMIM: 608564) ARF GTPase-activating protein  (631 aa)
 initn: 2949 init1: 1764 opt: 2754  Z-score: 1804.7  bits: 344.2 E(85289): 8.8e-94
Smith-Waterman score: 3851; 89.1% identity (90.9% similar) in 681 aa overlap (1-681:1-631)

               10        20        30        40        50        60
pF1KA0 MSKRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_476 MSKRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 LQMVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_476 LQMVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 PCRDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGNTPLHVASKAGQI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_476 PCRDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGNTPLHVASKAGQI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 LQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVEIQYELTDRLAFYLCGRKPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_476 LQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVEIQYELTDRLAFYLCGRKPD
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 HKNGQHFIIPQMADRRLSLDLSELAKAAKKKLQSLSNHLFEELAMDVYDEVDRRETDAVW
       ::::::::::::::   :::::::::::::::::::::::::::::::::::::::::::
NP_476 HKNGQHFIIPQMADS--SLDLSELAKAAKKKLQSLSNHLFEELAMDVYDEVDRRETDAVW
              250         260       270       280       290        

              310       320       330       340       350       360
pF1KA0 LATQNHSALVTETTVVPFLPVNPEYSSTRNQGRQKLARFNAHEFATLVIDILSDAKRRQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_476 LATQNHSALVTETTVVPFLPVNPEYSSTRNQGRQKLARFNAHEFATLVIDILSDAKRRQQ
      300       310       320       330       340       350        

              370       380       390       400       410       420
pF1KA0 GSSLSGSKDNVELILKTINNQHSVESQDNDQPDYDSVASDEDTDLETTASKTNRQKLQTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::    
NP_476 GSSLSGSKDNVELILKTINNQHSVESQDNDQPDYDSVASDEDTDLETTASKTNRQK----
      360       370       380       390       400       410        

              430       440       450       460       470       480
pF1KA0 QSENSNLRKQATTNVYQVQTGSEYTDTSNHSSLKRRPSARGSRPMSMYETGSGQKPYLPM
        : .:.:    .:    ::   :. ...:                            :  
NP_476 -SLDSDLSDGPVT----VQ---EFMEVKNA---------------------------LVA
           420              430                                    

              490       500       510       520       530       540
pF1KA0 GEASRPEESRMRLQPFPAHASRLEKQNSTPESDYDNTPNDMEPDGMGSSRKGRQRSMVWP
       .::        ..: .  .:::::::::::::::::::::::::::::::::::::::::
NP_476 SEA--------KIQQL-MKASRLEKQNSTPESDYDNTPNDMEPDGMGSSRKGRQRSMVWP
     440                450       460       470       480       490

              550       560       570       580       590       600
pF1KA0 GDGLVPDTAEPHVAPSPTLPSTEDVIRKTEQITKNIQELLRAAQENKHDSYIPCSERIHV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_476 GDGLVPDTAEPHVAPSPTLPSTEDVIRKTEQITKNIQELLRAAQENKHDSYIPCSERIHV
              500       510       520       530       540       550

              610       620       630       640       650       660
pF1KA0 AVTEMAALFPKKPKSDMVRTSLRLLTSSAYRLQSECKKTLPGDPGSPTDVQLVTQQVIQC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_476 AVTEMAALFPKKPKSDMVRTSLRLLTSSAYRLQSECKKTLPGDPGSPTDVQLVTQQVIQC
              560       570       580       590       600       610

              670       680 
pF1KA0 AYDIAKAAKQLVTITTKENNN
       :::::::::::::::::::::
NP_476 AYDIAKAAKQLVTITTKENNN
              620       630 

>>NP_001317083 (OMIM: 608564) ARF GTPase-activating prot  (421 aa)
 initn: 1764 init1: 1764 opt: 2746  Z-score: 1801.9  bits: 343.1 E(85289): 1.3e-93
Smith-Waterman score: 2746; 99.3% identity (99.3% similar) in 417 aa overlap (1-417:1-415)

               10        20        30        40        50        60
pF1KA0 MSKRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSKRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 LQMVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQMVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 PCRDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGNTPLHVASKAGQI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PCRDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGNTPLHVASKAGQI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 LQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVEIQYELTDRLAFYLCGRKPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVEIQYELTDRLAFYLCGRKPD
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 HKNGQHFIIPQMADRRLSLDLSELAKAAKKKLQSLSNHLFEELAMDVYDEVDRRETDAVW
       ::::::::::::::   :::::::::::::::::::::::::::::::::::::::::::
NP_001 HKNGQHFIIPQMADS--SLDLSELAKAAKKKLQSLSNHLFEELAMDVYDEVDRRETDAVW
              250         260       270       280       290        

              310       320       330       340       350       360
pF1KA0 LATQNHSALVTETTVVPFLPVNPEYSSTRNQGRQKLARFNAHEFATLVIDILSDAKRRQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LATQNHSALVTETTVVPFLPVNPEYSSTRNQGRQKLARFNAHEFATLVIDILSDAKRRQQ
      300       310       320       330       340       350        

              370       380       390       400       410       420
pF1KA0 GSSLSGSKDNVELILKTINNQHSVESQDNDQPDYDSVASDEDTDLETTASKTNRQKLQTL
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::   
NP_001 GSSLSGSKDNVELILKTINNQHSVESQDNDQPDYDSVASDEDTDLETTASKTNRQKLLGK
      360       370       380       390       400       410        

              430       440       450       460       470       480
pF1KA0 QSENSNLRKQATTNVYQVQTGSEYTDTSNHSSLKRRPSARGSRPMSMYETGSGQKPYLPM
                                                                   
NP_001 DAN                                                         
      420                                                          

>>XP_006719776 (OMIM: 608564) PREDICTED: ARF GTPase-acti  (456 aa)
 initn: 1764 init1: 1764 opt: 2744  Z-score: 1800.1  bits: 342.9 E(85289): 1.6e-93
Smith-Waterman score: 2744; 97.7% identity (98.6% similar) in 426 aa overlap (1-426:1-422)

               10        20        30        40        50        60
pF1KA0 MSKRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MSKRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 LQMVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LQMVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 PCRDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGNTPLHVASKAGQI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PCRDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGNTPLHVASKAGQI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 LQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVEIQYELTDRLAFYLCGRKPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVEIQYELTDRLAFYLCGRKPD
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 HKNGQHFIIPQMADRRLSLDLSELAKAAKKKLQSLSNHLFEELAMDVYDEVDRRETDAVW
       ::::::::::::::   :::::::::::::::::::::::::::::::::::::::::::
XP_006 HKNGQHFIIPQMADS--SLDLSELAKAAKKKLQSLSNHLFEELAMDVYDEVDRRETDAVW
              250         260       270       280       290        

              310       320       330       340       350       360
pF1KA0 LATQNHSALVTETTVVPFLPVNPEYSSTRNQGRQKLARFNAHEFATLVIDILSDAKRRQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LATQNHSALVTETTVVPFLPVNPEYSSTRNQGRQKLARFNAHEFATLVIDILSDAKRRQQ
      300       310       320       330       340       350        

              370       380       390       400       410       420
pF1KA0 GSSLSGSKDNVELILKTINNQHSVESQDNDQPDYDSVASDEDTDLETTASKTNRQKLQTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::  .:
XP_006 GSSLSGSKDNVELILKTINNQHSVESQDNDQPDYDSVASDEDTDLETTASKTNRQK--SL
      360       370       380       390       400       410        

              430       440       450       460       470       480
pF1KA0 QSENSNLRKQATTNVYQVQTGSEYTDTSNHSSLKRRPSARGSRPMSMYETGSGQKPYLPM
       .:. :.                                                      
XP_006 DSDLSDGPVTVQEFMEVKNALVASEAKIQQLMKLLGKDAN                    
        420       430       440       450                          

>>NP_631940 (OMIM: 608564) ARF GTPase-activating protein  (471 aa)
 initn: 1764 init1: 1764 opt: 2744  Z-score: 1799.9  bits: 342.9 E(85289): 1.6e-93
Smith-Waterman score: 2744; 97.7% identity (98.6% similar) in 426 aa overlap (1-426:1-422)

               10        20        30        40        50        60
pF1KA0 MSKRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_631 MSKRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 LQMVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_631 LQMVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 PCRDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGNTPLHVASKAGQI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_631 PCRDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGNTPLHVASKAGQI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 LQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVEIQYELTDRLAFYLCGRKPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_631 LQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVEIQYELTDRLAFYLCGRKPD
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 HKNGQHFIIPQMADRRLSLDLSELAKAAKKKLQSLSNHLFEELAMDVYDEVDRRETDAVW
       ::::::::::::::   :::::::::::::::::::::::::::::::::::::::::::
NP_631 HKNGQHFIIPQMADS--SLDLSELAKAAKKKLQSLSNHLFEELAMDVYDEVDRRETDAVW
              250         260       270       280       290        

              310       320       330       340       350       360
pF1KA0 LATQNHSALVTETTVVPFLPVNPEYSSTRNQGRQKLARFNAHEFATLVIDILSDAKRRQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_631 LATQNHSALVTETTVVPFLPVNPEYSSTRNQGRQKLARFNAHEFATLVIDILSDAKRRQQ
      300       310       320       330       340       350        

              370       380       390       400       410       420
pF1KA0 GSSLSGSKDNVELILKTINNQHSVESQDNDQPDYDSVASDEDTDLETTASKTNRQKLQTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::  .:
NP_631 GSSLSGSKDNVELILKTINNQHSVESQDNDQPDYDSVASDEDTDLETTASKTNRQK--SL
      360       370       380       390       400       410        

              430       440       450       460       470       480
pF1KA0 QSENSNLRKQATTNVYQVQTGSEYTDTSNHSSLKRRPSARGSRPMSMYETGSGQKPYLPM
       .:. :.                                                      
NP_631 DSDLSDGPVTVQEFMEVKNALVASEAKIQQLMKVNNNLSDELRIMQKKLLGKDAN     
        420       430       440       450       460       470      

>>XP_016875750 (OMIM: 608564) PREDICTED: ARF GTPase-acti  (470 aa)
 initn: 1760 init1: 1760 opt: 2743  Z-score: 1799.3  bits: 342.8 E(85289): 1.7e-93
Smith-Waterman score: 2743; 97.7% identity (98.6% similar) in 426 aa overlap (1-426:1-421)

               10        20        30        40        50        60
pF1KA0 MSKRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSKRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 LQMVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQMVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 PCRDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGNTPLHVASKAGQI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PCRDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGNTPLHVASKAGQI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 LQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVEIQYELTDRLAFYLCGRKPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVEIQYELTDRLAFYLCGRKPD
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 HKNGQHFIIPQMADRRLSLDLSELAKAAKKKLQSLSNHLFEELAMDVYDEVDRRETDAVW
       ::::::::::::::   :::::::::::::::::::::::::::::::::::::::::::
XP_016 HKNGQHFIIPQMAD---SLDLSELAKAAKKKLQSLSNHLFEELAMDVYDEVDRRETDAVW
              250          260       270       280       290       

              310       320       330       340       350       360
pF1KA0 LATQNHSALVTETTVVPFLPVNPEYSSTRNQGRQKLARFNAHEFATLVIDILSDAKRRQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LATQNHSALVTETTVVPFLPVNPEYSSTRNQGRQKLARFNAHEFATLVIDILSDAKRRQQ
       300       310       320       330       340       350       

              370       380       390       400       410       420
pF1KA0 GSSLSGSKDNVELILKTINNQHSVESQDNDQPDYDSVASDEDTDLETTASKTNRQKLQTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::  .:
XP_016 GSSLSGSKDNVELILKTINNQHSVESQDNDQPDYDSVASDEDTDLETTASKTNRQK--SL
       360       370       380       390       400       410       

              430       440       450       460       470       480
pF1KA0 QSENSNLRKQATTNVYQVQTGSEYTDTSNHSSLKRRPSARGSRPMSMYETGSGQKPYLPM
       .:. :.                                                      
XP_016 DSDLSDGPVTVQEFMEVKNALVASEAKIQQLMKVNNNLSDELRIMQKKLLGKDAN     
         420       430       440       450       460       470     




681 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Wed Nov  2 18:15:43 2016 done: Wed Nov  2 18:15:44 2016
 Total Scan time:  8.930 Total Display time:  0.120

Function used was FASTA [36.3.4 Apr, 2011]
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