Result of FASTA (omim) for
pFN21AE9424
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE9424, 361 aa
1>>>pF1KE9424 361 - 361 aa - 361 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.8948+/-0.000485; mu= 19.0391+/- 0.030
mean_var=123.8080+/-31.488, 0's: 0 Z-trim(109.4): 467 B-trim: 1053 in 1/49
Lambda= 0.115266
statistics sampled from 17017 (17597) to 17017 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.55), E-opt: 0.2 (0.206), width: 16
Scan time: 7.700
The best scores are: opt bits E(85289)
NP_001182684 (OMIM: 607514,609044) free fatty acid ( 361) 2378 407.6 2.2e-113
XP_011538048 (OMIM: 607514,609044) PREDICTED: free ( 240) 1519 264.5 1.8e-70
NP_859529 (OMIM: 607514,609044) free fatty acid re ( 377) 1521 265.1 1.8e-70
NP_000901 (OMIM: 162642) neuropeptide Y receptor t ( 381) 340 68.7 2.4e-11
XP_005263090 (OMIM: 162642) PREDICTED: neuropeptid ( 381) 340 68.7 2.4e-11
XP_005263091 (OMIM: 162642) PREDICTED: neuropeptid ( 381) 340 68.7 2.4e-11
NP_064552 (OMIM: 605108) neuromedin-U receptor 2 [ ( 415) 306 63.1 1.3e-09
XP_016881180 (OMIM: 600377) PREDICTED: galanin rec ( 269) 298 61.5 2.5e-09
NP_004239 (OMIM: 600895) prolactin-releasing pepti ( 370) 297 61.5 3.4e-09
NP_937822 (OMIM: 606925) pyroglutamylated RFamide ( 431) 294 61.1 5.2e-09
NP_001048 (OMIM: 162321) substance-K receptor [Hom ( 398) 292 60.8 6.3e-09
NP_001471 (OMIM: 600377) galanin receptor type 1 [ ( 349) 291 60.5 6.5e-09
NP_002502 (OMIM: 162341) neuromedin-B receptor iso ( 390) 291 60.6 7e-09
XP_005263088 (OMIM: 162641) PREDICTED: neuropeptid ( 384) 290 60.4 7.7e-09
XP_011530312 (OMIM: 162641) PREDICTED: neuropeptid ( 384) 290 60.4 7.7e-09
NP_000900 (OMIM: 162641) neuropeptide Y receptor t ( 384) 290 60.4 7.7e-09
NP_001718 (OMIM: 300107) bombesin receptor subtype ( 399) 288 60.1 1e-08
NP_005152 (OMIM: 600052) apelin receptor [Homo sap ( 380) 280 58.7 2.4e-08
NP_071429 (OMIM: 607448) neuropeptide FF receptor ( 430) 279 58.6 2.9e-08
NP_795344 (OMIM: 118445) gastrin/cholecystokinin t ( 447) 276 58.2 4.2e-08
XP_005253267 (OMIM: 118445) PREDICTED: gastrin/cho ( 516) 276 58.3 4.6e-08
NP_859528 (OMIM: 609042) opsin-5 [Homo sapiens] ( 354) 270 57.0 7.4e-08
XP_016865905 (OMIM: 609042) PREDICTED: opsin-5 iso ( 408) 270 57.1 8e-08
NP_444264 (OMIM: 607449) neuropeptide FF receptor ( 420) 269 57.0 9.2e-08
NP_001138228 (OMIM: 607449) neuropeptide FF recept ( 423) 269 57.0 9.2e-08
NP_004876 (OMIM: 607449) neuropeptide FF receptor ( 522) 269 57.1 1e-07
NP_000721 (OMIM: 118444) cholecystokinin receptor ( 428) 268 56.8 1e-07
NP_001043 (OMIM: 182454) somatostatin receptor typ ( 388) 267 56.6 1.1e-07
XP_011535972 (OMIM: 605108) PREDICTED: neuromedin- ( 321) 263 55.8 1.6e-07
NP_003848 (OMIM: 603691) galanin receptor type 2 [ ( 387) 263 55.9 1.7e-07
XP_016884412 (OMIM: 182453) PREDICTED: somatostati ( 418) 263 56.0 1.8e-07
XP_016884413 (OMIM: 182453) PREDICTED: somatostati ( 418) 263 56.0 1.8e-07
XP_005261778 (OMIM: 182453) PREDICTED: somatostati ( 418) 263 56.0 1.8e-07
NP_001265616 (OMIM: 182453) somatostatin receptor ( 418) 263 56.0 1.8e-07
XP_006724374 (OMIM: 182453) PREDICTED: somatostati ( 418) 263 56.0 1.8e-07
XP_011528651 (OMIM: 182453) PREDICTED: somatostati ( 418) 263 56.0 1.8e-07
NP_001042 (OMIM: 182453) somatostatin receptor typ ( 418) 263 56.0 1.8e-07
XP_006713023 (OMIM: 601268) PREDICTED: C-C chemoki ( 355) 260 55.4 2.4e-07
NP_847899 (OMIM: 601268) C-C chemokine receptor ty ( 355) 260 55.4 2.4e-07
XP_011531637 (OMIM: 601268) PREDICTED: C-C chemoki ( 355) 260 55.4 2.4e-07
NP_001828 (OMIM: 601268) C-C chemokine receptor ty ( 355) 260 55.4 2.4e-07
NP_001158152 (OMIM: 601268) C-C chemokine receptor ( 373) 260 55.4 2.4e-07
NP_847898 (OMIM: 601268) C-C chemokine receptor ty ( 376) 260 55.4 2.4e-07
XP_016861175 (OMIM: 601268) PREDICTED: C-C chemoki ( 410) 260 55.5 2.6e-07
XP_016861174 (OMIM: 601268) PREDICTED: C-C chemoki ( 410) 260 55.5 2.6e-07
NP_778227 (OMIM: 608282) trace amine-associated re ( 348) 259 55.2 2.6e-07
NP_003982 (OMIM: 131244,277580,600155,600501) endo ( 436) 259 55.3 3e-07
NP_055441 (OMIM: 604849) trace amine-associated re ( 306) 254 54.3 4.3e-07
NP_001028252 (OMIM: 604849) trace amine-associated ( 351) 254 54.4 4.7e-07
NP_001495 (OMIM: 300574) C-X-C chemokine receptor ( 368) 254 54.4 4.8e-07
>>NP_001182684 (OMIM: 607514,609044) free fatty acid rec (361 aa)
initn: 2378 init1: 2378 opt: 2378 Z-score: 2156.5 bits: 407.6 E(85289): 2.2e-113
Smith-Waterman score: 2378; 100.0% identity (100.0% similar) in 361 aa overlap (1-361:1-361)
10 20 30 40 50 60
pF1KE9 MSPECARAAGDAPLRSLEQANRTRFPFFSDVKGDHRLVLAAVETTVLVLIFAVSLLGNVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSPECARAAGDAPLRSLEQANRTRFPFFSDVKGDHRLVLAAVETTVLVLIFAVSLLGNVC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 ALVLVARRRRRGATACLVLNLFCADLLFISAIPLVLAVRWTEAWLLGPVACHLLFYVMTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALVLVARRRRRGATACLVLNLFCADLLFISAIPLVLAVRWTEAWLLGPVACHLLFYVMTL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 SGSVTILTLAAVSLERMVCIVHLQRGVRGPGRRARAVLLALIWGYSAVAALPLCVFFRVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGSVTILTLAAVSLERMVCIVHLQRGVRGPGRRARAVLLALIWGYSAVAALPLCVFFRVV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 PQRLPGADQEISICTLIWPTIPGEISWDVSFVTLNFLVPGLVIVISYSKILQITKASRKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQRLPGADQEISICTLIWPTIPGEISWDVSFVTLNFLVPGLVIVISYSKILQITKASRKR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 LTVSLAYSESHQIRVSQQDFRLFRTLFLLMVSFFIMWSPIIITILLILIQNFKQDLVIWP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTVSLAYSESHQIRVSQQDFRLFRTLFLLMVSFFIMWSPIIITILLILIQNFKQDLVIWP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 SLFFWVVAFTFANSALNPILYNMTLCRNEWKKIFCCFWFPEKGAILTDTSVKRNDLSIIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLFFWVVAFTFANSALNPILYNMTLCRNEWKKIFCCFWFPEKGAILTDTSVKRNDLSIIS
310 320 330 340 350 360
pF1KE9 G
:
NP_001 G
>>XP_011538048 (OMIM: 607514,609044) PREDICTED: free fat (240 aa)
initn: 1519 init1: 1519 opt: 1519 Z-score: 1386.2 bits: 264.5 E(85289): 1.8e-70
Smith-Waterman score: 1519; 100.0% identity (100.0% similar) in 232 aa overlap (1-232:1-232)
10 20 30 40 50 60
pF1KE9 MSPECARAAGDAPLRSLEQANRTRFPFFSDVKGDHRLVLAAVETTVLVLIFAVSLLGNVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSPECARAAGDAPLRSLEQANRTRFPFFSDVKGDHRLVLAAVETTVLVLIFAVSLLGNVC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 ALVLVARRRRRGATACLVLNLFCADLLFISAIPLVLAVRWTEAWLLGPVACHLLFYVMTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALVLVARRRRRGATACLVLNLFCADLLFISAIPLVLAVRWTEAWLLGPVACHLLFYVMTL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 SGSVTILTLAAVSLERMVCIVHLQRGVRGPGRRARAVLLALIWGYSAVAALPLCVFFRVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGSVTILTLAAVSLERMVCIVHLQRGVRGPGRRARAVLLALIWGYSAVAALPLCVFFRVV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 PQRLPGADQEISICTLIWPTIPGEISWDVSFVTLNFLVPGLVIVISYSKILQITKASRKR
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PQRLPGADQEISICTLIWPTIPGEISWDVSFVTLNFLVPGLVIVISYSKILQARVHLEKF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 LTVSLAYSESHQIRVSQQDFRLFRTLFLLMVSFFIMWSPIIITILLILIQNFKQDLVIWP
>>NP_859529 (OMIM: 607514,609044) free fatty acid recept (377 aa)
initn: 1521 init1: 1521 opt: 1521 Z-score: 1386.1 bits: 265.1 E(85289): 1.8e-70
Smith-Waterman score: 2336; 95.8% identity (95.8% similar) in 377 aa overlap (1-361:1-377)
10 20 30 40 50 60
pF1KE9 MSPECARAAGDAPLRSLEQANRTRFPFFSDVKGDHRLVLAAVETTVLVLIFAVSLLGNVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_859 MSPECARAAGDAPLRSLEQANRTRFPFFSDVKGDHRLVLAAVETTVLVLIFAVSLLGNVC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 ALVLVARRRRRGATACLVLNLFCADLLFISAIPLVLAVRWTEAWLLGPVACHLLFYVMTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_859 ALVLVARRRRRGATACLVLNLFCADLLFISAIPLVLAVRWTEAWLLGPVACHLLFYVMTL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 SGSVTILTLAAVSLERMVCIVHLQRGVRGPGRRARAVLLALIWGYSAVAALPLCVFFRVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_859 SGSVTILTLAAVSLERMVCIVHLQRGVRGPGRRARAVLLALIWGYSAVAALPLCVFFRVV
130 140 150 160 170 180
190 200 210 220 230
pF1KE9 PQRLPGADQEISICTLIWPTIPGEISWDVSFVTLNFLVPGLVIVISYSKILQ--------
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_859 PQRLPGADQEISICTLIWPTIPGEISWDVSFVTLNFLVPGLVIVISYSKILQTSEHLLDA
190 200 210 220 230 240
240 250 260 270 280
pF1KE9 --------ITKASRKRLTVSLAYSESHQIRVSQQDFRLFRTLFLLMVSFFIMWSPIIITI
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_859 RAVVTHSEITKASRKRLTVSLAYSESHQIRVSQQDFRLFRTLFLLMVSFFIMWSPIIITI
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE9 LLILIQNFKQDLVIWPSLFFWVVAFTFANSALNPILYNMTLCRNEWKKIFCCFWFPEKGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_859 LLILIQNFKQDLVIWPSLFFWVVAFTFANSALNPILYNMTLCRNEWKKIFCCFWFPEKGA
310 320 330 340 350 360
350 360
pF1KE9 ILTDTSVKRNDLSIISG
:::::::::::::::::
NP_859 ILTDTSVKRNDLSIISG
370
>>NP_000901 (OMIM: 162642) neuropeptide Y receptor type (381 aa)
initn: 249 init1: 127 opt: 340 Z-score: 324.6 bits: 68.7 E(85289): 2.4e-11
Smith-Waterman score: 348; 29.1% identity (57.3% similar) in 323 aa overlap (46-351:52-355)
20 30 40 50 60 70
pF1KE9 SLEQANRTRFPFFSDVKGDHRLVLAAVETTVLVLIF-AVSLLG----NVCALVLVARRRR
::.: . .. ::: .. :.. .
NP_000 YGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSIILLGVIGNSLVIHVVIKFKSM
30 40 50 60 70 80
80 90 100 110 120
pF1KE9 RGATACLVLNLFCADLLFIS-AIPLVLAVRWTEAWLLGPVACHLLFYVMTLSGSVTILTL
: .: .. :: :::: . .:..:. : .::: :::. :.. :. .:. .::
NP_000 RTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITL
90 100 110 120 130 140
130 140 150 160 170 180
pF1KE9 AAVSLERMVCIV-HLQRGVRGPGRRARAVLLALIWGYSAVAALPLCVFFRV-VPQRLPGA
....:.: ::: ::. . ..: ....: :: ::. : :: .: . . . .:
NP_000 TVIALDRHRCIVYHLESKI---SKRISFLIIGLAWGISALLASPLAIFREYSLIEIIP--
150 160 170 180 190
190 200 210 220 230 240
pF1KE9 DQEISICTLIWP----TIPGEISWDVSFVTLNFLVPGLVIVISYSKILQITKASRKRLTV
: :: :: :: .: : . ...: . . ...: .: .::..: . : ....
NP_000 DFEIVACTEKWPGEEKSIYGTV-YSLSSLLILYVLPLGIISFSYTRIWSKLK---NHVSP
200 210 220 230 240 250
250 260 270 280 290 300
pF1KE9 SLAYSESHQIRVSQQDFRLFRTLFLLMVSFFIMWSPIIITILLILIQNFKQDLVIWPSLF
. : .. :: : :. .. : ..: : . : :. : . :.. :: . .:
NP_000 GAANDHYHQRR--QKTTKM---LVCVVVVFAVSWLPLHAFQLAVDIDSQVLDLKEYKLIF
260 270 280 290 300
310 320 330 340 350
pF1KE9 --FWVVAF--TFANSALNPILYNMTLCRNEWKKIFCCFWFPEK-GAILTDTSVKRNDLSI
: ..:. ::: ::.::. . : : .. : .. :: ...::
NP_000 TVFHIIAMCSTFA----NPLLYGW-MNSNYRKAFLSAFRCEQRLDAIHSEVSVTFKAKKN
310 320 330 340 350 360
360
pF1KE9 ISG
NP_000 LEVRKNSGPNDSFTEATNV
370 380
>>XP_005263090 (OMIM: 162642) PREDICTED: neuropeptide Y (381 aa)
initn: 249 init1: 127 opt: 340 Z-score: 324.6 bits: 68.7 E(85289): 2.4e-11
Smith-Waterman score: 348; 29.1% identity (57.3% similar) in 323 aa overlap (46-351:52-355)
20 30 40 50 60 70
pF1KE9 SLEQANRTRFPFFSDVKGDHRLVLAAVETTVLVLIF-AVSLLG----NVCALVLVARRRR
::.: . .. ::: .. :.. .
XP_005 YGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSIILLGVIGNSLVIHVVIKFKSM
30 40 50 60 70 80
80 90 100 110 120
pF1KE9 RGATACLVLNLFCADLLFIS-AIPLVLAVRWTEAWLLGPVACHLLFYVMTLSGSVTILTL
: .: .. :: :::: . .:..:. : .::: :::. :.. :. .:. .::
XP_005 RTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITL
90 100 110 120 130 140
130 140 150 160 170 180
pF1KE9 AAVSLERMVCIV-HLQRGVRGPGRRARAVLLALIWGYSAVAALPLCVFFRV-VPQRLPGA
....:.: ::: ::. . ..: ....: :: ::. : :: .: . . . .:
XP_005 TVIALDRHRCIVYHLESKI---SKRISFLIIGLAWGISALLASPLAIFREYSLIEIIP--
150 160 170 180 190
190 200 210 220 230 240
pF1KE9 DQEISICTLIWP----TIPGEISWDVSFVTLNFLVPGLVIVISYSKILQITKASRKRLTV
: :: :: :: .: : . ...: . . ...: .: .::..: . : ....
XP_005 DFEIVACTEKWPGEEKSIYGTV-YSLSSLLILYVLPLGIISFSYTRIWSKLK---NHVSP
200 210 220 230 240 250
250 260 270 280 290 300
pF1KE9 SLAYSESHQIRVSQQDFRLFRTLFLLMVSFFIMWSPIIITILLILIQNFKQDLVIWPSLF
. : .. :: : :. .. : ..: : . : :. : . :.. :: . .:
XP_005 GAANDHYHQRR--QKTTKM---LVCVVVVFAVSWLPLHAFQLAVDIDSQVLDLKEYKLIF
260 270 280 290 300
310 320 330 340 350
pF1KE9 --FWVVAF--TFANSALNPILYNMTLCRNEWKKIFCCFWFPEK-GAILTDTSVKRNDLSI
: ..:. ::: ::.::. . : : .. : .. :: ...::
XP_005 TVFHIIAMCSTFA----NPLLYGW-MNSNYRKAFLSAFRCEQRLDAIHSEVSVTFKAKKN
310 320 330 340 350 360
360
pF1KE9 ISG
XP_005 LEVRKNSGPNDSFTEATNV
370 380
>>XP_005263091 (OMIM: 162642) PREDICTED: neuropeptide Y (381 aa)
initn: 249 init1: 127 opt: 340 Z-score: 324.6 bits: 68.7 E(85289): 2.4e-11
Smith-Waterman score: 348; 29.1% identity (57.3% similar) in 323 aa overlap (46-351:52-355)
20 30 40 50 60 70
pF1KE9 SLEQANRTRFPFFSDVKGDHRLVLAAVETTVLVLIF-AVSLLG----NVCALVLVARRRR
::.: . .. ::: .. :.. .
XP_005 YGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSIILLGVIGNSLVIHVVIKFKSM
30 40 50 60 70 80
80 90 100 110 120
pF1KE9 RGATACLVLNLFCADLLFIS-AIPLVLAVRWTEAWLLGPVACHLLFYVMTLSGSVTILTL
: .: .. :: :::: . .:..:. : .::: :::. :.. :. .:. .::
XP_005 RTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITL
90 100 110 120 130 140
130 140 150 160 170 180
pF1KE9 AAVSLERMVCIV-HLQRGVRGPGRRARAVLLALIWGYSAVAALPLCVFFRV-VPQRLPGA
....:.: ::: ::. . ..: ....: :: ::. : :: .: . . . .:
XP_005 TVIALDRHRCIVYHLESKI---SKRISFLIIGLAWGISALLASPLAIFREYSLIEIIP--
150 160 170 180 190
190 200 210 220 230 240
pF1KE9 DQEISICTLIWP----TIPGEISWDVSFVTLNFLVPGLVIVISYSKILQITKASRKRLTV
: :: :: :: .: : . ...: . . ...: .: .::..: . : ....
XP_005 DFEIVACTEKWPGEEKSIYGTV-YSLSSLLILYVLPLGIISFSYTRIWSKLK---NHVSP
200 210 220 230 240 250
250 260 270 280 290 300
pF1KE9 SLAYSESHQIRVSQQDFRLFRTLFLLMVSFFIMWSPIIITILLILIQNFKQDLVIWPSLF
. : .. :: : :. .. : ..: : . : :. : . :.. :: . .:
XP_005 GAANDHYHQRR--QKTTKM---LVCVVVVFAVSWLPLHAFQLAVDIDSQVLDLKEYKLIF
260 270 280 290 300
310 320 330 340 350
pF1KE9 --FWVVAF--TFANSALNPILYNMTLCRNEWKKIFCCFWFPEK-GAILTDTSVKRNDLSI
: ..:. ::: ::.::. . : : .. : .. :: ...::
XP_005 TVFHIIAMCSTFA----NPLLYGW-MNSNYRKAFLSAFRCEQRLDAIHSEVSVTFKAKKN
310 320 330 340 350 360
360
pF1KE9 ISG
XP_005 LEVRKNSGPNDSFTEATNV
370 380
>>NP_064552 (OMIM: 605108) neuromedin-U receptor 2 [Homo (415 aa)
initn: 210 init1: 142 opt: 306 Z-score: 293.7 bits: 63.1 E(85289): 1.3e-09
Smith-Waterman score: 306; 27.9% identity (59.2% similar) in 326 aa overlap (13-323:21-329)
10 20 30 40 50
pF1KE9 MSPECARAAGDAPLRSLEQANRTRFPFFSDVKGDHRLVLAAVETTVLVLIFA
:... .... . :. . .: .. ..: : : ::.
NP_064 MSGMEKLQNASWIYQQKLEDPFQKHLNSTEEYLAFLCGPRRSHFFLPVSV---VYVPIFV
10 20 30 40 50
60 70 80 90 100
pF1KE9 VSLLGNV--CALVLVARRRRRGATACLVLNLFCADLL-FISAIPLVLAVRWTE-AWLLGP
:...::: : ::.. .. . : ...: .::: .. ..:: . : . .:.::
NP_064 VGVIGNVLVC-LVILQHQAMKTPTNYYLFSLAVSDLLVLLLGMPLEVYEMWRNYPFLFGP
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE9 VACHLLFYVMTLSGSVTILTLAAVSLERMVCIVHLQRGVRGPGRRARAVLLALIWGYSAV
:.:.. .. ..::....::.::.: :.: :. :: .:...::.:..
NP_064 VGCYFKTALFETVCFASILSITTVSVERYVAILHPFRAKLQSTRRRALRILGIVWGFSVL
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE9 AALPLC----VFFRVVPQR--LPGADQEISICTLIWPT-IPGEISWDVSFVTLNFLVPGL
.:: . :. :. .::. . ::.: : : . : .:: : .:.:
NP_064 FSLPNTSIHGIKFHYFPNGSLVPGS----ATCTVIKPMWIYNFIIQVTSF--LFYLLPMT
180 190 200 210 220 230
230 240 250 260 270
pF1KE9 VIVISYSKILQITKASRKRLTVSLAYSESHQIRVSQQDFR--LFRTLFLLMVSFFIMWSP
:: . : . : : . :: .:.. :. : . . ::.:.. : : :.:
NP_064 VISVLYYLM-----ALRLKKDKSLEADEGNA--NIQRPCRKSVNKMLFVLVLVFAICWAP
240 250 260 270 280
280 290 300 310 320 330
pF1KE9 IIITILLI-LIQNFKQDLVIWPSLFFWVVA-FTFANSALNPILYNMTLCRNEWKKIFCCF
. : :.. ........:. .: : . : . .::.:::.::.
NP_064 FHIDRLFFSFVEEWSESLAAVFNLVHVVSGVFFYLSSAVNPIIYNLLSRRFQAAFQNVIS
290 300 310 320 330 340
340 350 360
pF1KE9 WFPEKGAILTDTSVKRNDLSIISG
NP_064 SFHKQWHSQHDPQLPPAQRNIFLTECHFVELTEDIGPQFPCQSSMHNSHLPAALSSEQMS
350 360 370 380 390 400
>>XP_016881180 (OMIM: 600377) PREDICTED: galanin recepto (269 aa)
initn: 224 init1: 159 opt: 298 Z-score: 288.4 bits: 61.5 E(85289): 2.5e-09
Smith-Waterman score: 298; 30.0% identity (62.1% similar) in 240 aa overlap (42-274:35-265)
20 30 40 50 60 70
pF1KE9 APLRSLEQANRTRFPFFSDVKGDHRLVLAAVETTVLVLIFAVSLLGNVCALVLVARRRR-
: .:. ::::...::: .....:: .
XP_016 VGNLSEGNASWPEPPAPEPGPLFGIGVENFVTLVVFGLIFALGVLGNSLVITVLARSKPG
10 20 30 40 50 60
80 90 100 110 120
pF1KE9 --RGATACLVLNLFCADLLFIS-AIPLVLAVRWTEAWLLGPVACHLLFYVMTLSGSVTIL
:..: ..::: ::: .. ::. .: .:.:: :... : .:.: :.:.
XP_016 KPRSTTNLFILNLSIADLAYLLFCIPFQATVYALPTWVLGAFICKFIHYFFTVSMLVSIF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 TLAAVSLERMVCIVHLQRGVRGPGRRARAVLLAL--IWGYSAVAALPLCVFFRVVPQRLP
::::.:..:.: ::: .:. . : .: .::.. ::. : . : :. . :
XP_016 TLAAMSVDRYVAIVHSRRS--SSLRVSRNALLGVGCIWALSIAMASPVAYHQGLFHPR--
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 GADQEISICTLIWPTIPGEISWDVSFVTLNFLVPGLVIVISYSKILQITKASRKRLTVSL
...: ..: :: . .. : ....:.: :.: . :.:.:. . . : .. .
XP_016 ASNQ--TFCWEQWPDPRHKKAYVVCTFVFGYLLPLLLICFCYAKVLNHLHKKLKNMSKK-
190 200 210 220 230
250 260 270 280 290 300
pF1KE9 AYSESHQIRVSQQDFR-LFRTLFLLMVSFFIMWSPIIITILLILIQNFKQDLVIWPSLFF
::. . .:. .: .... ::..:
XP_016 --SEASKKKVQGASFGWIYHSGVWRMVALFSQIH
240 250 260
>>NP_004239 (OMIM: 600895) prolactin-releasing peptide r (370 aa)
initn: 202 init1: 97 opt: 297 Z-score: 286.1 bits: 61.5 E(85289): 3.4e-09
Smith-Waterman score: 337; 27.5% identity (56.7% similar) in 353 aa overlap (2-344:24-358)
10 20 30
pF1KE9 MSPECARAAGDAPLRSLEQANRTRFPFFSDVKGDHRLV
.: : ..: :. :. :.... :.:
NP_004 MASSTTRGPRVSDLFSGLPPAVTTPANQSAEASAGNGSVAGADAPAVTPFQSLQLVHQLK
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE9 LAAVETTVLVLIFAVSLLGNVCALVLVARRRRR--GATACLVLNLFCADLLFISA-IPLV
: .:.. :.:.:: : :::: : :: ..: :. :: .:.:. .: .::.
NP_004 GLIVLLYSVVVV--VGLVGN-CLLVLVIARVRRLHNVTNFLIGNLALSDVLMCTACVPLT
70 80 90 100 110
100 110 120 130 140 150
pF1KE9 LAVRWT-EAWLLGPVACHLLFYVMTLSGSVTILTLAAVSLERMVCIVHLQRGVRGPGRRA
:: . ..:..: :::.:... .. :...::......:.: .:: : : . :
NP_004 LAYAFEPRGWVFGGGLCHLVFFLQPVTVYVSVFTLTTIAVDRYVVLVHPLR--RRISLRL
120 130 140 150 160 170
160 170 180 190 200 210
pF1KE9 RAVLLALIWGYSAVAALPLCVFFRVVPQRLPGADQEISICTLIWPTIPGE---ISWDVSF
: . ::. ::: ::: : : . : ... .: .: . . .: . .
NP_004 SAYAVLAIWALSAVLALPAAVHTYHVELK-P---HDVRLCEEFWGSQERQRQLYAWGLLL
180 190 200 210 220 230
220 230 240 250 260 270
pF1KE9 VTLNFLVPGLVIVISYSKILQITKASRKRLTVS-LAYSESHQIRVSQQDFRLFRTLFLLM
:: .:.: :::..:: .... :.:.. . .. :.. :. .. : : : ...
NP_004 VT--YLLPLLVILLSY---VRVSVKLRNRVVPGCVTQSQADWDRARRR--RTFCLLVVVV
240 250 260 270 280
280 290 300 310 320
pF1KE9 VSFFIMWSPIIITILLILIQNFKQDLVIWPSLFFWVVAFTFANSALNPILYNMTL--CRN
: : . : :. . :: .. : . . . ...... ::..: :.
NP_004 VVFAVCWLPLHVFNLLRDLDPHAIDPYAFGLVQLLCHWLAMSSACYNPFIYAWLHDSFRE
290 300 310 320 330 340
330 340 350 360
pF1KE9 EWKKIFCCFWFPEKGAILTDTSVKRNDLSIISG
: .:.. : :.: :
NP_004 ELRKLLVA-W-PRKIAPHGQNMTVSVVI
350 360 370
>>NP_937822 (OMIM: 606925) pyroglutamylated RFamide pept (431 aa)
initn: 222 init1: 146 opt: 294 Z-score: 282.7 bits: 61.1 E(85289): 5.2e-09
Smith-Waterman score: 294; 26.2% identity (58.5% similar) in 313 aa overlap (36-336:43-350)
10 20 30 40 50 60
pF1KE9 ARAAGDAPLRSLEQANRTRFPFFSDVKGDHRLVLAAVETTVLVLIFAVSLLGNVCALVLV
: :: : : : ::::..:.::. .. .:
NP_937 RLLRDHNLTREQFIALYRLRPLVYTPELPGRAKLALVLTGV--LIFALALFGNALVFYVV
20 30 40 50 60 70
70 80 90 100 110 120
pF1KE9 ARRRR-RGATACLVLNLFCADLLF-ISAIPLVLAVRWTEAWLLGPVACHLLFYVMTLSGS
.: . : .: .. .: .:::. . ::... .. :: : :... .:.. .
NP_937 TRSKAMRTVTNIFICSLALSDLLITFFCIPVTMLQNISDNWLGGAFICKMVPFVQSTAVV
80 90 100 110 120 130
130 140 150 160 170 180
pF1KE9 VTILTLAAVSLERMVCIVH-LQRGVRGPGRRARAVLLALIWGYSAVAALPLCVFFRVVPQ
. :::.. ...:: .:: .. . .::: . .:...: ..... :. . .
NP_937 TEILTMTCIAVERHQGLVHPFKMKWQYTNRRAFT-MLGVVWLVAVIVGSPM-WHVQQLEI
140 150 160 170 180
190 200 210 220 230 240
pF1KE9 RLPGADQEISICTLIWPTIPGEISWDVSFV-TLNFLVPGLVIVISYSKILQITKASRKRL
. .. :: : : : . . ..:. .. ::.: .:..: :::: .::.
NP_937 KYDFLYEKEHICCLEEWTSPVHQKIYTTFILVILFLLPLMVMLILYSKI-GYELWIKKRV
190 200 210 220 230 240
250 260 270 280 290
pF1KE9 TVSLAYSESHQIRVSQQDFRLFRTLFLLM--VSFF-IMWSPIIITILLILIQNFKQ--DL
. . : ..:. . :...... :..: . :.:. .. ..: .::.. :
NP_937 GDGSVLRTIHGKEMSKIARKKKRAVIMMVTVVALFAVCWAPFHVVHMMIEYSNFEKEYDD
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE9 VIWPSLFFWVVAFTFANSALNPILY---NMTLCRNEWKKIFCCFWFPEKGAILTDTSVKR
: .: : . :.:: :::.: : .. .: . . :
NP_937 VTIKMIFAIVQIIGFSNSICNPIVYAFMNENFKKNVLSAVCYCIVNKTFSPAQRHGNSGI
310 320 330 340 350 360
360
pF1KE9 NDLSIISG
NP_937 TMMRKKAKFSLRENPVEETKGEAFSDGNIEVKLCEQTEEKKKLKRHLALFRSELAENSPL
370 380 390 400 410 420
361 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 12:36:56 2016 done: Sun Nov 6 12:36:57 2016
Total Scan time: 7.700 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]