Result of FASTA (omim) for
pFN21AE6654
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6654, 244 aa
1>>>pF1KE6654 244 - 244 aa - 244 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.8045+/-0.000399; mu= 17.1697+/- 0.025
mean_var=72.2770+/-15.134, 0's: 0 Z-trim(111.3): 128 B-trim: 0 in 0/49
Lambda= 0.150860
statistics sampled from 19684 (19828) to 19684 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.6), E-opt: 0.2 (0.232), width: 16
Scan time: 4.320
The best scores are: opt bits E(85289)
NP_057370 (OMIM: 260800,608347) L-xylulose reducta ( 244) 1580 353.2 2.4e-97
NP_001182147 (OMIM: 260800,608347) L-xylulose redu ( 242) 1553 347.3 1.4e-95
NP_066284 (OMIM: 611596) dehydrogenase/reductase S ( 278) 383 92.7 7.1e-19
NP_057330 (OMIM: 612832) 17-beta-hydroxysteroid de ( 270) 320 79.0 9.3e-15
NP_065715 (OMIM: 615839) peroxisomal 2,4-dienoyl-C ( 292) 309 76.6 5.2e-14
NP_055049 (OMIM: 601417) estradiol 17-beta-dehydro ( 261) 299 74.4 2.2e-13
XP_005267306 (OMIM: 615194) PREDICTED: dehydrogena ( 280) 299 74.4 2.3e-13
NP_005785 (OMIM: 615194) dehydrogenase/reductase S ( 280) 299 74.4 2.3e-13
XP_006720064 (OMIM: 615194) PREDICTED: dehydrogena ( 280) 299 74.4 2.3e-13
NP_878912 (OMIM: 615194) dehydrogenase/reductase S ( 300) 264 66.9 4.7e-11
XP_005259026 (OMIM: 612832) PREDICTED: 17-beta-hyd ( 212) 261 66.1 5.7e-11
NP_932349 (OMIM: 615196) dehydrogenase/reductase S ( 232) 256 65.0 1.3e-10
NP_001269917 (OMIM: 611596) dehydrogenase/reductas ( 244) 232 59.8 5e-09
XP_011534640 (OMIM: 615194) PREDICTED: dehydrogena ( 204) 222 57.6 2e-08
XP_011534641 (OMIM: 615194) PREDICTED: dehydrogena ( 204) 222 57.6 2e-08
XP_006720309 (OMIM: 615195) PREDICTED: putative de ( 244) 213 55.7 8.8e-08
XP_016868636 (OMIM: 222745) PREDICTED: 2,4-dienoyl ( 326) 214 56.0 9.4e-08
XP_011515182 (OMIM: 222745) PREDICTED: 2,4-dienoyl ( 326) 214 56.0 9.4e-08
NP_001317504 (OMIM: 222745) 2,4-dienoyl-CoA reduct ( 326) 214 56.0 9.4e-08
XP_016868637 (OMIM: 222745) PREDICTED: 2,4-dienoyl ( 326) 214 56.0 9.4e-08
NP_001350 (OMIM: 222745) 2,4-dienoyl-CoA reductase ( 335) 214 56.0 9.6e-08
XP_005250865 (OMIM: 222745) PREDICTED: 2,4-dienoyl ( 243) 205 53.9 2.9e-07
NP_057329 (OMIM: 612831) estradiol 17-beta-dehydro ( 300) 204 53.8 4e-07
NP_835236 (OMIM: 612127) 17-beta-hydroxysteroid de ( 300) 203 53.6 4.6e-07
NP_001180565 (OMIM: 615196) dehydrogenase/reductas ( 131) 198 52.2 5.4e-07
NP_001264793 (OMIM: 615195) putative dehydrogenase ( 150) 189 50.3 2.3e-06
XP_016881179 (OMIM: 136440) PREDICTED: 3-ketodihyd ( 255) 182 48.9 9.8e-06
XP_005266734 (OMIM: 136440) PREDICTED: 3-ketodihyd ( 298) 182 49.0 1.1e-05
NP_004484 (OMIM: 300220,300256,300438) 3-hydroxyac ( 261) 178 48.1 1.8e-05
NP_000851 (OMIM: 119900,259100,601688) 15-hydroxyp ( 266) 173 47.0 3.9e-05
NP_056540 (OMIM: 608575) retinol dehydrogenase 8 [ ( 331) 170 46.4 7.2e-05
NP_002896 (OMIM: 136880,601617) 11-cis retinol deh ( 318) 167 45.8 0.00011
NP_001186700 (OMIM: 136880,601617) 11-cis retinol ( 318) 167 45.8 0.00011
XP_011518458 (OMIM: 609574) PREDICTED: very-long-c ( 238) 163 44.8 0.00016
NP_620419 (OMIM: 608989) epidermal retinol dehydro ( 309) 164 45.1 0.00017
NP_001304978 (OMIM: 608989) epidermal retinol dehy ( 318) 164 45.1 0.00017
NP_000404 (OMIM: 109684) estradiol 17-beta-dehydro ( 328) 164 45.1 0.00018
XP_005257349 (OMIM: 109684) PREDICTED: estradiol 1 ( 359) 164 45.2 0.00019
XP_011523032 (OMIM: 109684) PREDICTED: estradiol 1 ( 383) 164 45.2 0.0002
XP_006721921 (OMIM: 109684) PREDICTED: estradiol 1 ( 414) 164 45.2 0.00021
NP_861420 (OMIM: 600713,614662) corticosteroid 11- ( 292) 161 44.4 0.00026
NP_005516 (OMIM: 600713,614662) corticosteroid 11- ( 292) 161 44.4 0.00026
NP_001193670 (OMIM: 600713,614662) corticosteroid ( 292) 161 44.4 0.00026
XP_016870162 (OMIM: 264300,605573) PREDICTED: test ( 298) 161 44.4 0.00026
NP_683695 (OMIM: 609769) short-chain dehydrogenase ( 313) 160 44.2 0.00031
NP_002144 (OMIM: 109685) estradiol 17-beta-dehydro ( 387) 160 44.3 0.00037
NP_001135742 (OMIM: 612131) dehydrogenase/reductas ( 319) 159 44.0 0.00037
XP_011508777 (OMIM: 612131) PREDICTED: dehydrogena ( 319) 159 44.0 0.00037
NP_001135743 (OMIM: 612131) dehydrogenase/reductas ( 319) 159 44.0 0.00037
NP_954674 (OMIM: 612131) dehydrogenase/reductase S ( 319) 159 44.0 0.00037
>>NP_057370 (OMIM: 260800,608347) L-xylulose reductase i (244 aa)
initn: 1580 init1: 1580 opt: 1580 Z-score: 1868.6 bits: 353.2 E(85289): 2.4e-97
Smith-Waterman score: 1580; 100.0% identity (100.0% similar) in 244 aa overlap (1-244:1-244)
10 20 30 40 50 60
pF1KE6 MELFLAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIEPVCVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MELFLAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIEPVCVD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 LGDWEATERALGSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 LGDWEATERALGSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVAR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 GLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 GLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 VVMTSMGQATWSDPHKAKTMLNRIPLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 VVMTSMGQATWSDPHKAKTMLNRIPLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGG
190 200 210 220 230 240
pF1KE6 FWAC
::::
NP_057 FWAC
>>NP_001182147 (OMIM: 260800,608347) L-xylulose reductas (242 aa)
initn: 1474 init1: 1474 opt: 1553 Z-score: 1836.9 bits: 347.3 E(85289): 1.4e-95
Smith-Waterman score: 1553; 99.2% identity (99.2% similar) in 244 aa overlap (1-244:1-242)
10 20 30 40 50 60
pF1KE6 MELFLAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIEPVCVD
:::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::
NP_001 MELFLAGRRVLVTGAGKG--RGTVQALHATGARVVAVSRTQADLDSLVRECPGIEPVCVD
10 20 30 40 50
70 80 90 100 110 120
pF1KE6 LGDWEATERALGSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGDWEATERALGSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVAR
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE6 GLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPT
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE6 VVMTSMGQATWSDPHKAKTMLNRIPLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVMTSMGQATWSDPHKAKTMLNRIPLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGG
180 190 200 210 220 230
pF1KE6 FWAC
::::
NP_001 FWAC
240
>>NP_066284 (OMIM: 611596) dehydrogenase/reductase SDR f (278 aa)
initn: 289 init1: 211 opt: 383 Z-score: 459.9 bits: 92.7 E(85289): 7.1e-19
Smith-Waterman score: 383; 32.2% identity (63.7% similar) in 245 aa overlap (5-240:30-273)
10 20 30
pF1KE6 MELFLAGRRVLVTGAGKGIGRGTVQALHATGARVV
::.. .:::.. ::: . .. : ::.::
NP_066 MHKAGLLGLCARAWNSVRMASSGMTRRDPLANKVALVTASTDGIGFAIARRLAQDGAHVV
10 20 30 40 50 60
40 50 60 70 80
pF1KE6 AVSRTQADLDSLVRECPG----IEPVCVDLGDWEATERALGSV----GPVDLLVNNAAVA
. :: : ..:. : : . . .: : :: .... : .:.::.::::
NP_066 VSSRKQQNVDQAVATLQGEGLSVTGTVCHVGKAEDRERLVATAVKLHGGIDILVSNAAVN
70 80 90 100 110 120
90 100 110 120 130 140
pF1KE6 -LLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNH
.. ...::.:..:.....:..: ... :. . :: :..: ::: . .
NP_066 PFFGSIMDVTEEVWDKTLDINVKAPALMTKAVVPEMEKRG-GGSVVIVSSIAAFSPSPGF
130 140 150 160 170
150 160 170 180 190 200
pF1KE6 SVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSMGQATWSDPHKAKTMLNRIPL
: : .: :: :::..:.::.:..:::: . : .. ::... : : .: ..: . . .
NP_066 SPYNVSKTALLGLTKTLAIELAPRNIRVNCLAPGLIKTSFSRMLWMDKEKEESMKETLRI
180 190 200 210 220 230
210 220 230 240
pF1KE6 GKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGGFWAC
...: : .. . :: :. ... :: :. : ::
NP_066 RRLGEPEDCAGIVSFLCSEDASYITGETVVVGGGTPSRL
240 250 260 270
>>NP_057330 (OMIM: 612832) 17-beta-hydroxysteroid dehydr (270 aa)
initn: 283 init1: 137 opt: 320 Z-score: 385.9 bits: 79.0 E(85289): 9.3e-15
Smith-Waterman score: 320; 30.5% identity (61.0% similar) in 246 aa overlap (6-240:8-248)
10 20 30 40 50
pF1KE6 MELFLAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIEPVC
::. :.:::.:.::: : :.:. .::::: .. .. .: .: :: .
NP_057 MATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFIL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 VDLGDWEATERALGSV----GPVDLLVNNAA--VALLQPFLEVTKEAFDRSFEVNLRAVI
:. . . .. .. . : .: .::::. .: :.. ..: . .:.:: ..
NP_057 CDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPE-ETSAQGFRQLLELNLLGTY
70 80 90 100 110
120 130 140 150 160 170
pF1KE6 QVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKI
..... : : : ..:.:: . . .. : .::::. .::..::. .:. .
NP_057 TLTKLALPYL--RKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGV
120 130 140 150 160 170
180 190 200 210 220
pF1KE6 RVNAVNPTVVMTSMGQ---ATWSDPHKA--KTMLNRIPLGKFAEVEHVVNAILFLLSDRS
::: ..: . : . . : ::. . . :: . :::.... .: : .:: :. .
NP_057 RVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQ-PLGRMGQPAEVGAAAVFLASE-A
180 190 200 210 220 230
230 240
pF1KE6 GMTTGSTLPVEGGFWAC
.. :: : : ::
NP_057 NFCTGIELLVTGGAELGYGCKASRSTPVDAPDIPS
240 250 260 270
>>NP_065715 (OMIM: 615839) peroxisomal 2,4-dienoyl-CoA r (292 aa)
initn: 239 init1: 109 opt: 309 Z-score: 372.6 bits: 76.6 E(85289): 5.2e-14
Smith-Waterman score: 309; 25.7% identity (63.1% similar) in 249 aa overlap (4-242:25-272)
10 20 30
pF1KE6 MELFLAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSR
.: . ...::.:.::: .. . : ..: .::
NP_065 MAQPPPDVEGDDCLPAYRHLFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASR
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE6 TQADLDSLVRECPGIE-----PVCVDL----GDWEATERALGSVGPVDLLVNNAAVALLQ
. . . .:. : :. .:. . :...:: : .:.:.: :: .:
NP_065 SLPRVLTAARKLAGATGRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLC
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE6 PFLEVTKEAFDRSFEVNLRAVIQVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYC
: .. .:: .... ....::... . .. : :.:::... ..:. . .
NP_065 PAGALSFNAFKTVMDIDTSGTFNVSRVLYEKFF-RDHGGVIVNITATLGNRGQALQVHAG
130 140 150 160 170
160 170 180 190 200
pF1KE6 STKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSMGQATWSDPHKA-KTMLNRIPLGKF
:.:.:.: .:. .:.: ::..::::.. : . . : . :. . .: .. :: ..
NP_065 SAKAAVDAMTRHLAVEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRL
180 190 200 210 220 230
210 220 230 240
pF1KE6 AEVEHVVNAILFLLSDRSGMTTGSTLPVEGGFWAC
.. ......:.: : ....::..: ..:: :
NP_065 GNKTEIAHSVLYLASPLASYVTGAVLVADGGAWLTFPNGVKGLPDFASFSAKL
240 250 260 270 280 290
>>NP_055049 (OMIM: 601417) estradiol 17-beta-dehydrogena (261 aa)
initn: 341 init1: 174 opt: 299 Z-score: 361.4 bits: 74.4 E(85289): 2.2e-13
Smith-Waterman score: 344; 30.9% identity (64.7% similar) in 249 aa overlap (11-242:15-260)
10 20 30 40 50
pF1KE6 MELFLAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVREC--PGI
::::::.::::.. : . :: :.: . .: . :: ::
NP_055 MASQLQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGS
10 20 30 40 50 60
60 70 80 90 100
pF1KE6 E--P-------VCVDLGDWEATERALGSVG-----PVDLLVNNAAVALLQPFLEVTKEAF
. : .:... .:.. : .: : ...:. :... . .:..... .
NP_055 KEGPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDW
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE6 DRSFEVNLRAVIQVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLT
:. . :::.... :.: .:..:.. : :.:.:.:: .. . .... : ..:... ::
NP_055 DKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLT
130 140 150 160 170 180
170 180 190 200 210
pF1KE6 KVMALELGPHKIRVNAVNPTVVMTSMGQATWSDPHKA-KTMLNRIPLGKFAEVEHVVNAI
.. : ::: : :: :.: : . : : : . :.:. . . ::.:.... : :....
NP_055 QTAARELGRHGIRCNSVLPGFIATPMTQKV---PQKVVDKITEMIPMGHLGDPEDVADVV
190 200 210 220 230
220 230 240
pF1KE6 LFLLSDRSGMTTGSTLPVEGGFWAC
:: :. ::. ::... : ::..
NP_055 AFLASEDSGYITGTSVEVTGGLFM
240 250 260
>>XP_005267306 (OMIM: 615194) PREDICTED: dehydrogenase/r (280 aa)
initn: 303 init1: 172 opt: 299 Z-score: 361.0 bits: 74.4 E(85289): 2.3e-13
Smith-Waterman score: 299; 30.2% identity (60.0% similar) in 245 aa overlap (5-239:34-275)
10 20 30
pF1KE6 MELFLAGRRVLVTGAGKGIGRGTVQALHATGARV
::.: ..:::. .::: . .. : ::.:
XP_005 AVARGYQGWFHPCARLSVRMSSTGIDRKGVLANRVAVVTGSTSGIGFAIARRLARDGAHV
10 20 30 40 50 60
40 50 60 70 80
pF1KE6 VAVSRTQADLDSLVRECPG----IEPVCVDLGDWEATE----RALGSVGPVDLLVNNAAV
: :: : ..: . . : . . .: : : .:: : ::.:: .:.:
XP_005 VISSRKQQNVDRAMAKLQGEGLSVAGIVCHVGKAEDREQLVAKALEHCGGVDFLVCSAGV
70 80 90 100 110 120
90 100 110 120 130 140
pF1KE6 A-LLQPFLEVTKEAFDRSFEVNLRA-VIQVSQIVARGLIARGVPGAIVNVSSQCSQRAVT
:. : .... .:. . ::... .. .::.. : ::.. ::: . :.
XP_005 NPLVGSTLGTSEQIWDKILSVNVKSPALLLSQLLPYMENRR---GAVILVSSIAAYNPVV
130 140 150 160 170 180
150 160 170 180 190 200
pF1KE6 NHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSMGQATWSDPHKAKTMLNRI
.:: .: :: ::...::::.:. :::: : : .. :..... .. :.. ..
XP_005 ALGVYNVSKTALLGLTRTLALELAPKDIRVNCVVPGIIKTDFSKVFHGNESLWKNFKEHH
190 200 210 220 230 240
210 220 230 240
pF1KE6 PLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGGFWAC
: ...: : .. . :: : .....: .. : :
XP_005 QLQRIGESEDCAGIVSFLCSPDASYVNGENIAVAGYSTRL
250 260 270 280
>>NP_005785 (OMIM: 615194) dehydrogenase/reductase SDR f (280 aa)
initn: 303 init1: 172 opt: 299 Z-score: 361.0 bits: 74.4 E(85289): 2.3e-13
Smith-Waterman score: 299; 30.2% identity (60.0% similar) in 245 aa overlap (5-239:34-275)
10 20 30
pF1KE6 MELFLAGRRVLVTGAGKGIGRGTVQALHATGARV
::.: ..:::. .::: . .. : ::.:
NP_005 AVARGYQGWFHPCARLSVRMSSTGIDRKGVLANRVAVVTGSTSGIGFAIARRLARDGAHV
10 20 30 40 50 60
40 50 60 70 80
pF1KE6 VAVSRTQADLDSLVRECPG----IEPVCVDLGDWEATE----RALGSVGPVDLLVNNAAV
: :: : ..: . . : . . .: : : .:: : ::.:: .:.:
NP_005 VISSRKQQNVDRAMAKLQGEGLSVAGIVCHVGKAEDREQLVAKALEHCGGVDFLVCSAGV
70 80 90 100 110 120
90 100 110 120 130 140
pF1KE6 A-LLQPFLEVTKEAFDRSFEVNLRA-VIQVSQIVARGLIARGVPGAIVNVSSQCSQRAVT
:. : .... .:. . ::... .. .::.. : ::.. ::: . :.
NP_005 NPLVGSTLGTSEQIWDKILSVNVKSPALLLSQLLPYMENRR---GAVILVSSIAAYNPVV
130 140 150 160 170 180
150 160 170 180 190 200
pF1KE6 NHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSMGQATWSDPHKAKTMLNRI
.:: .: :: ::...::::.:. :::: : : .. :..... .. :.. ..
NP_005 ALGVYNVSKTALLGLTRTLALELAPKDIRVNCVVPGIIKTDFSKVFHGNESLWKNFKEHH
190 200 210 220 230 240
210 220 230 240
pF1KE6 PLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGGFWAC
: ...: : .. . :: : .....: .. : :
NP_005 QLQRIGESEDCAGIVSFLCSPDASYVNGENIAVAGYSTRL
250 260 270 280
>>XP_006720064 (OMIM: 615194) PREDICTED: dehydrogenase/r (280 aa)
initn: 303 init1: 172 opt: 299 Z-score: 361.0 bits: 74.4 E(85289): 2.3e-13
Smith-Waterman score: 299; 30.2% identity (60.0% similar) in 245 aa overlap (5-239:34-275)
10 20 30
pF1KE6 MELFLAGRRVLVTGAGKGIGRGTVQALHATGARV
::.: ..:::. .::: . .. : ::.:
XP_006 AVARGYQGWFHPCARLSVRMSSTGIDRKGVLANRVAVVTGSTSGIGFAIARRLARDGAHV
10 20 30 40 50 60
40 50 60 70 80
pF1KE6 VAVSRTQADLDSLVRECPG----IEPVCVDLGDWEATE----RALGSVGPVDLLVNNAAV
: :: : ..: . . : . . .: : : .:: : ::.:: .:.:
XP_006 VISSRKQQNVDRAMAKLQGEGLSVAGIVCHVGKAEDREQLVAKALEHCGGVDFLVCSAGV
70 80 90 100 110 120
90 100 110 120 130 140
pF1KE6 A-LLQPFLEVTKEAFDRSFEVNLRA-VIQVSQIVARGLIARGVPGAIVNVSSQCSQRAVT
:. : .... .:. . ::... .. .::.. : ::.. ::: . :.
XP_006 NPLVGSTLGTSEQIWDKILSVNVKSPALLLSQLLPYMENRR---GAVILVSSIAAYNPVV
130 140 150 160 170 180
150 160 170 180 190 200
pF1KE6 NHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSMGQATWSDPHKAKTMLNRI
.:: .: :: ::...::::.:. :::: : : .. :..... .. :.. ..
XP_006 ALGVYNVSKTALLGLTRTLALELAPKDIRVNCVVPGIIKTDFSKVFHGNESLWKNFKEHH
190 200 210 220 230 240
210 220 230 240
pF1KE6 PLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGGFWAC
: ...: : .. . :: : .....: .. : :
XP_006 QLQRIGESEDCAGIVSFLCSPDASYVNGENIAVAGYSTRL
250 260 270 280
>>NP_878912 (OMIM: 615194) dehydrogenase/reductase SDR f (300 aa)
initn: 268 init1: 137 opt: 264 Z-score: 319.5 bits: 66.9 E(85289): 4.7e-11
Smith-Waterman score: 264; 33.0% identity (60.3% similar) in 194 aa overlap (5-188:34-224)
10 20 30
pF1KE6 MELFLAGRRVLVTGAGKGIGRGTVQALHATGARV
::.: ..:::. .::: . .. : ::.:
NP_878 AVARGYQGWFHPCARLSVRMSSTGIDRKGVLANRVAVVTGSTSGIGFAIARRLARDGAHV
10 20 30 40 50 60
40 50 60 70 80
pF1KE6 VAVSRTQADLDSLVRECPG----IEPVCVDLGDWEATE----RALGSVGPVDLLVNNAAV
: :: : ..: . . : . . .: : : .:: : ::.:: .:.:
NP_878 VISSRKQQNVDRAMAKLQGEGLSVAGIVCHVGKAEDREQLVAKALEHCGGVDFLVCSAGV
70 80 90 100 110 120
90 100 110 120 130 140
pF1KE6 A-LLQPFLEVTKEAFDRSFEVNLRA-VIQVSQIVARGLIARGVPGAIVNVSSQCSQRAVT
:. : .... .:. . ::... .. .::.. :: :.. ::: . :.
NP_878 NPLVGSTLGTSEQIWDKILSVNVKSPALLLSQLLPYMENRRG---AVILVSSIAAYNPVV
130 140 150 160 170 180
150 160 170 180 190 200
pF1KE6 NHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSMGQATWSDPHKAKTMLNRI
.:: .: :: ::...::::.:. :::: : : .. :....
NP_878 ALGVYNVSKTALLGLTRTLALELAPKDIRVNCVVPGIIKTDFSKVVRIGFMGMSLSGRTS
190 200 210 220 230 240
210 220 230 240
pF1KE6 PLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGGFWAC
NP_878 RNIISCRGLGSQRTVQESCPSCALQMPATSTGRTLRWQATPLGSERSGGGCVAVVPGPGA
250 260 270 280 290 300
244 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 15:09:33 2016 done: Tue Nov 8 15:09:34 2016
Total Scan time: 4.320 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]