Result of FASTA (omim) for
pFN21AB6562
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6562, 399 aa
1>>>pF1KB6562 399 - 399 aa - 399 aa
Library: /omim/omim.rfq.tfa
64369986 residues in 92320 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.1703+/-0.000491; mu= -8.9896+/- 0.030
mean_var=644.0176+/-142.783, 0's: 0 Z-trim(121.3): 1289 B-trim: 0 in 0/54
Lambda= 0.050539
statistics sampled from 37138 (39180) to 37138 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.751), E-opt: 0.2 (0.424), width: 16
Scan time: 4.560
The best scores are: opt bits E(92320)
NP_003001 (OMIM: 601335) dual specificity mitogen- ( 399) 2710 212.7 1.4e-54
NP_001268364 (OMIM: 601335) dual specificity mitog ( 410) 2479 195.9 1.6e-49
XP_005256810 (OMIM: 601335) dual specificity mitog ( 281) 1899 153.4 7e-37
XP_011522278 (OMIM: 601335) dual specificity mitog ( 319) 1776 144.5 3.8e-34
XP_005256812 (OMIM: 601335) dual specificity mitog ( 253) 1723 140.5 4.8e-33
XP_011522279 (OMIM: 601335) dual specificity mitog ( 253) 1723 140.5 4.8e-33
NP_002749 (OMIM: 601254) dual specificity mitogen- ( 334) 1200 102.5 1.7e-21
XP_011523328 (OMIM: 601254) dual specificity mitog ( 337) 1200 102.5 1.7e-21
XP_006722038 (OMIM: 601254) dual specificity mitog ( 278) 1166 99.9 8.6e-21
NP_001317379 (OMIM: 601254) dual specificity mitog ( 278) 1166 99.9 8.6e-21
XP_005257573 (OMIM: 601254) dual specificity mitog ( 278) 1166 99.9 8.6e-21
XP_011523329 (OMIM: 601254) dual specificity mitog ( 278) 1166 99.9 8.6e-21
XP_016880348 (OMIM: 602315) dual specificity mitog ( 318) 1147 98.6 2.4e-20
NP_002747 (OMIM: 602315) dual specificity mitogen- ( 318) 1147 98.6 2.4e-20
XP_011522261 (OMIM: 602315) dual specificity mitog ( 318) 1147 98.6 2.4e-20
NP_001303261 (OMIM: 602315) dual specificity mitog ( 318) 1147 98.6 2.4e-20
XP_005256780 (OMIM: 602315) dual specificity mitog ( 318) 1147 98.6 2.4e-20
XP_016880347 (OMIM: 602315) dual specificity mitog ( 318) 1147 98.6 2.4e-20
XP_016880346 (OMIM: 602315) dual specificity mitog ( 343) 1147 98.7 2.5e-20
NP_659731 (OMIM: 602315) dual specificity mitogen- ( 347) 1147 98.7 2.5e-20
NP_001284484 (OMIM: 603014) dual specificity mitog ( 435) 1000 88.1 4.9e-17
NP_660186 (OMIM: 603014) dual specificity mitogen- ( 419) 995 87.7 6.1e-17
XP_006722863 (OMIM: 603014) dual specificity mitog ( 442) 976 86.4 1.6e-16
NP_001284485 (OMIM: 603014) dual specificity mitog ( 426) 971 86.0 2.1e-16
XP_011522260 (OMIM: 602315) dual specificity mitog ( 298) 907 81.1 4.3e-15
XP_011520085 (OMIM: 163950,176872,615279) dual spe ( 371) 612 59.7 1.5e-08
NP_002746 (OMIM: 163950,176872,615279) dual specif ( 393) 612 59.7 1.5e-08
NP_109587 (OMIM: 601263,615280) dual specificity m ( 400) 612 59.8 1.5e-08
XP_016882478 (OMIM: 601263,615280) dual specificit ( 512) 612 59.9 1.7e-08
XP_024305756 (OMIM: 602520) dual specificity mitog ( 371) 553 55.4 2.9e-07
NP_001193733 (OMIM: 602520) dual specificity mitog ( 412) 553 55.5 3e-07
NP_660143 (OMIM: 602520) dual specificity mitogen- ( 448) 553 55.5 3.2e-07
XP_016869247 (OMIM: 605030) serine/threonine-prote ( 456) 552 55.5 3.4e-07
NP_001243241 (OMIM: 605030) serine/threonine-prote ( 519) 553 55.6 3.5e-07
XP_016869246 (OMIM: 605030) serine/threonine-prote ( 524) 553 55.6 3.5e-07
NP_006272 (OMIM: 605030) serine/threonine-protein ( 491) 552 55.5 3.5e-07
XP_011515553 (OMIM: 605030) serine/threonine-prote ( 522) 552 55.5 3.7e-07
XP_011515550 (OMIM: 605030) serine/threonine-prote ( 576) 553 55.7 3.7e-07
XP_016869245 (OMIM: 605030) serine/threonine-prote ( 580) 553 55.7 3.7e-07
XP_016883522 (OMIM: 604965,614868) serine/threonin ( 388) 545 54.8 4.4e-07
XP_011527322 (OMIM: 604965,614868) serine/threonin ( 404) 545 54.9 4.5e-07
NP_001339314 (OMIM: 604965,614868) serine/threonin ( 462) 545 55.0 4.9e-07
XP_005260588 (OMIM: 604965,614868) serine/threonin ( 478) 545 55.0 5e-07
NP_006273 (OMIM: 604965,614868) serine/threonine-p ( 487) 545 55.0 5e-07
XP_005260587 (OMIM: 604965,614868) serine/threonin ( 503) 545 55.0 5.1e-07
XP_016883521 (OMIM: 604965,614868) serine/threonin ( 458) 521 53.2 1.6e-06
XP_016883518 (OMIM: 604965,614868) serine/threonin ( 474) 521 53.2 1.7e-06
XP_016883519 (OMIM: 604965,614868) serine/threonin ( 474) 521 53.2 1.7e-06
XP_005260589 (OMIM: 604965,614868) serine/threonin ( 474) 521 53.2 1.7e-06
XP_016883520 (OMIM: 604965,614868) serine/threonin ( 474) 521 53.2 1.7e-06
>>NP_003001 (OMIM: 601335) dual specificity mitogen-acti (399 aa)
initn: 2710 init1: 2710 opt: 2710 Z-score: 1101.7 bits: 212.7 E(92320): 1.4e-54
Smith-Waterman score: 2710; 100.0% identity (100.0% similar) in 399 aa overlap (1-399:1-399)
10 20 30 40 50 60
pF1KB6 MAAPSPSGGGGSGGGSGSGTPGPVGSPAPGHPAVSSMQGKRKALKLNFANPPFKSTARFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MAAPSPSGGGGSGGGSGSGTPGPVGSPAPGHPAVSSMQGKRKALKLNFANPPFKSTARFT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 LNPNPTGVQNPHIERLRTHSIESSGKLKISPEQHWDFTAEDLKDLGEIGRGAYGSVNKMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LNPNPTGVQNPHIERLRTHSIESSGKLKISPEQHWDFTAEDLKDLGEIGRGAYGSVNKMV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 HKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALFREGDCWICMEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 HKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALFREGDCWICMEL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 MSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNILLDRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNILLDRS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 GNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQGYDVRSDVWSLGITLYEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQGYDVRSDVWSLGITLYEL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 ATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSPSFINFVNLCLTKDESKRPKYKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSPSFINFVNLCLTKDESKRPKYKE
310 320 330 340 350 360
370 380 390
pF1KB6 LLKHPFILMYEERAVEVACYVCKILDQMPATPSSPMYVD
:::::::::::::::::::::::::::::::::::::::
NP_003 LLKHPFILMYEERAVEVACYVCKILDQMPATPSSPMYVD
370 380 390
>>NP_001268364 (OMIM: 601335) dual specificity mitogen-a (410 aa)
initn: 2437 init1: 2437 opt: 2479 Z-score: 1010.6 bits: 195.9 E(92320): 1.6e-49
Smith-Waterman score: 2678; 97.3% identity (97.3% similar) in 410 aa overlap (1-399:1-410)
10 20 30 40
pF1KB6 MAAPSPSGGGGSGGGSGSGTPGPVGSPAPGHPAVSSMQG-----------KRKALKLNFA
::::::::::::::::::::::::::::::::::::::: ::::::::::
NP_001 MAAPSPSGGGGSGGGSGSGTPGPVGSPAPGHPAVSSMQGFQINFCEKAQSKRKALKLNFA
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB6 NPPFKSTARFTLNPNPTGVQNPHIERLRTHSIESSGKLKISPEQHWDFTAEDLKDLGEIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NPPFKSTARFTLNPNPTGVQNPHIERLRTHSIESSGKLKISPEQHWDFTAEDLKDLGEIG
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB6 RGAYGSVNKMVHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGAYGSVNKMVHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALF
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB6 REGDCWICMELMSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REGDCWICMELMSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRD
190 200 210 220 230 240
230 240 250 260 270 280
pF1KB6 IKPSNILLDRSGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQGYDVRSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IKPSNILLDRSGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQGYDVRSD
250 260 270 280 290 300
290 300 310 320 330 340
pF1KB6 VWSLGITLYELATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSPSFINFVNLCLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VWSLGITLYELATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSPSFINFVNLCLT
310 320 330 340 350 360
350 360 370 380 390
pF1KB6 KDESKRPKYKELLKHPFILMYEERAVEVACYVCKILDQMPATPSSPMYVD
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KDESKRPKYKELLKHPFILMYEERAVEVACYVCKILDQMPATPSSPMYVD
370 380 390 400 410
>>XP_005256810 (OMIM: 601335) dual specificity mitogen-a (281 aa)
initn: 1899 init1: 1899 opt: 1899 Z-score: 783.7 bits: 153.4 E(92320): 7e-37
Smith-Waterman score: 1899; 100.0% identity (100.0% similar) in 281 aa overlap (119-399:1-281)
90 100 110 120 130 140
pF1KB6 ISPEQHWDFTAEDLKDLGEIGRGAYGSVNKMVHKPSGQIMAVKRIRSTVDEKEQKQLLMD
::::::::::::::::::::::::::::::
XP_005 MVHKPSGQIMAVKRIRSTVDEKEQKQLLMD
10 20 30
150 160 170 180 190 200
pF1KB6 LDVVMRSSDCPYIVQFYGALFREGDCWICMELMSTSFDKFYKYVYSVLDDVIPEEILGKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LDVVMRSSDCPYIVQFYGALFREGDCWICMELMSTSFDKFYKYVYSVLDDVIPEEILGKI
40 50 60 70 80 90
210 220 230 240 250 260
pF1KB6 TLATVKALNHLKENLKIIHRDIKPSNILLDRSGNIKLCDFGISGQLVDSIAKTRDAGCRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TLATVKALNHLKENLKIIHRDIKPSNILLDRSGNIKLCDFGISGQLVDSIAKTRDAGCRP
100 110 120 130 140 150
270 280 290 300 310 320
pF1KB6 YMAPERIDPSASRQGYDVRSDVWSLGITLYELATGRFPYPKWNSVFDQLTQVVKGDPPQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YMAPERIDPSASRQGYDVRSDVWSLGITLYELATGRFPYPKWNSVFDQLTQVVKGDPPQL
160 170 180 190 200 210
330 340 350 360 370 380
pF1KB6 SNSEEREFSPSFINFVNLCLTKDESKRPKYKELLKHPFILMYEERAVEVACYVCKILDQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SNSEEREFSPSFINFVNLCLTKDESKRPKYKELLKHPFILMYEERAVEVACYVCKILDQM
220 230 240 250 260 270
390
pF1KB6 PATPSSPMYVD
:::::::::::
XP_005 PATPSSPMYVD
280
>>XP_011522278 (OMIM: 601335) dual specificity mitogen-a (319 aa)
initn: 1734 init1: 1734 opt: 1776 Z-score: 734.7 bits: 144.5 E(92320): 3.8e-34
Smith-Waterman score: 1975; 96.4% identity (96.4% similar) in 308 aa overlap (1-297:1-308)
10 20 30 40
pF1KB6 MAAPSPSGGGGSGGGSGSGTPGPVGSPAPGHPAVSSMQG-----------KRKALKLNFA
::::::::::::::::::::::::::::::::::::::: ::::::::::
XP_011 MAAPSPSGGGGSGGGSGSGTPGPVGSPAPGHPAVSSMQGFQINFCEKAQSKRKALKLNFA
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB6 NPPFKSTARFTLNPNPTGVQNPHIERLRTHSIESSGKLKISPEQHWDFTAEDLKDLGEIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NPPFKSTARFTLNPNPTGVQNPHIERLRTHSIESSGKLKISPEQHWDFTAEDLKDLGEIG
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB6 RGAYGSVNKMVHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RGAYGSVNKMVHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALF
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB6 REGDCWICMELMSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REGDCWICMELMSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRD
190 200 210 220 230 240
230 240 250 260 270 280
pF1KB6 IKPSNILLDRSGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQGYDVRSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKPSNILLDRSGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQGYDVRSD
250 260 270 280 290 300
290 300 310 320 330 340
pF1KB6 VWSLGITLYELATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSPSFINFVNLCLT
::::::::
XP_011 VWSLGITLIIGVNYYLQLH
310
>>XP_005256812 (OMIM: 601335) dual specificity mitogen-a (253 aa)
initn: 1723 init1: 1723 opt: 1723 Z-score: 714.8 bits: 140.5 E(92320): 4.8e-33
Smith-Waterman score: 1723; 100.0% identity (100.0% similar) in 253 aa overlap (147-399:1-253)
120 130 140 150 160 170
pF1KB6 NKMVHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALFREGDCWI
::::::::::::::::::::::::::::::
XP_005 MDLDVVMRSSDCPYIVQFYGALFREGDCWI
10 20 30
180 190 200 210 220 230
pF1KB6 CMELMSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CMELMSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNIL
40 50 60 70 80 90
240 250 260 270 280 290
pF1KB6 LDRSGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQGYDVRSDVWSLGIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LDRSGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQGYDVRSDVWSLGIT
100 110 120 130 140 150
300 310 320 330 340 350
pF1KB6 LYELATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSPSFINFVNLCLTKDESKRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LYELATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSPSFINFVNLCLTKDESKRP
160 170 180 190 200 210
360 370 380 390
pF1KB6 KYKELLKHPFILMYEERAVEVACYVCKILDQMPATPSSPMYVD
:::::::::::::::::::::::::::::::::::::::::::
XP_005 KYKELLKHPFILMYEERAVEVACYVCKILDQMPATPSSPMYVD
220 230 240 250
>>XP_011522279 (OMIM: 601335) dual specificity mitogen-a (253 aa)
initn: 1723 init1: 1723 opt: 1723 Z-score: 714.8 bits: 140.5 E(92320): 4.8e-33
Smith-Waterman score: 1723; 100.0% identity (100.0% similar) in 253 aa overlap (147-399:1-253)
120 130 140 150 160 170
pF1KB6 NKMVHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALFREGDCWI
::::::::::::::::::::::::::::::
XP_011 MDLDVVMRSSDCPYIVQFYGALFREGDCWI
10 20 30
180 190 200 210 220 230
pF1KB6 CMELMSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CMELMSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNIL
40 50 60 70 80 90
240 250 260 270 280 290
pF1KB6 LDRSGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQGYDVRSDVWSLGIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDRSGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQGYDVRSDVWSLGIT
100 110 120 130 140 150
300 310 320 330 340 350
pF1KB6 LYELATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSPSFINFVNLCLTKDESKRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LYELATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSPSFINFVNLCLTKDESKRP
160 170 180 190 200 210
360 370 380 390
pF1KB6 KYKELLKHPFILMYEERAVEVACYVCKILDQMPATPSSPMYVD
:::::::::::::::::::::::::::::::::::::::::::
XP_011 KYKELLKHPFILMYEERAVEVACYVCKILDQMPATPSSPMYVD
220 230 240 250
>>NP_002749 (OMIM: 601254) dual specificity mitogen-acti (334 aa)
initn: 1201 init1: 586 opt: 1200 Z-score: 507.5 bits: 102.5 E(92320): 1.7e-21
Smith-Waterman score: 1200; 54.9% identity (81.1% similar) in 317 aa overlap (69-385:21-332)
40 50 60 70 80 90
pF1KB6 GKRKALKLNFANPPFKSTARFTLNPNPTGVQNPHIERLRTHSIESSGKLKISPEQHWDFT
..:. ....:.. ..:. .:...
NP_002 MSQSKGKKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIG-NQNFEVK
10 20 30 40
100 110 120 130 140 150
pF1KB6 AEDLKDLGEIGRGAYGSVNKMVHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDC
:.::. . :.:::::: :.:: : ::::::::::::.::. .:::.::::::. ::. ::
NP_002 ADDLEPIMELGRGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDC
50 60 70 80 90 100
160 170 180 190 200 210
pF1KB6 PYIVQFYGALFREGDCWICMELMSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNH
:. : :::::::::: :::::::.::.::::: : . ..:::.:::::... ::::.:
NP_002 PFTVTFYGALFREGDVWICMELMDTSLDKFYKQVIDK-GQTIPEDILGKIAVSIVKALEH
110 120 130 140 150 160
220 230 240 250 260 270
pF1KB6 LKENLKIIHRDIKPSNILLDRSGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPS
:. .:..::::.::::.:.. :..:.::::::: ::::.::: ::::.::::::::.:
NP_002 LHSKLSVIHRDVKPSNVLINALGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPE
170 180 190 200 210 220
280 290 300 310 320 330
pF1KB6 ASRQGYDVRSDVWSLGITLYELATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSP
...::.:.::.::::::. ::: :::: .:.. :.:: :::. ::: .. ::
NP_002 LNQKGYSVKSDIWSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADK---FSA
230 240 250 260 270 280
340 350 360 370 380 390
pF1KB6 SFINFVNLCLTKDESKRPKYKELLKHPFILMYEERAVEVACYVCKILDQMPATPSSPMYV
:..:.. :: :. ..:: : ::..:::. ..: ....:: .: ::
NP_002 EFVDFTSQCLKKNSKERPTYPELMQHPFFTLHESKGTDVASFVKLILGD
290 300 310 320 330
pF1KB6 D
>>XP_011523328 (OMIM: 601254) dual specificity mitogen-a (337 aa)
initn: 1201 init1: 586 opt: 1200 Z-score: 507.5 bits: 102.5 E(92320): 1.7e-21
Smith-Waterman score: 1200; 54.9% identity (81.1% similar) in 317 aa overlap (69-385:24-335)
40 50 60 70 80 90
pF1KB6 GKRKALKLNFANPPFKSTARFTLNPNPTGVQNPHIERLRTHSIESSGKLKISPEQHWDFT
..:. ....:.. ..:. .:...
XP_011 MSHRAWAEGKKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIG-NQNFEVK
10 20 30 40 50
100 110 120 130 140 150
pF1KB6 AEDLKDLGEIGRGAYGSVNKMVHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDC
:.::. . :.:::::: :.:: : ::::::::::::.::. .:::.::::::. ::. ::
XP_011 ADDLEPIMELGRGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDC
60 70 80 90 100 110
160 170 180 190 200 210
pF1KB6 PYIVQFYGALFREGDCWICMELMSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNH
:. : :::::::::: :::::::.::.::::: : . ..:::.:::::... ::::.:
XP_011 PFTVTFYGALFREGDVWICMELMDTSLDKFYKQVIDK-GQTIPEDILGKIAVSIVKALEH
120 130 140 150 160 170
220 230 240 250 260 270
pF1KB6 LKENLKIIHRDIKPSNILLDRSGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPS
:. .:..::::.::::.:.. :..:.::::::: ::::.::: ::::.::::::::.:
XP_011 LHSKLSVIHRDVKPSNVLINALGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPE
180 190 200 210 220 230
280 290 300 310 320 330
pF1KB6 ASRQGYDVRSDVWSLGITLYELATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSP
...::.:.::.::::::. ::: :::: .:.. :.:: :::. ::: .. ::
XP_011 LNQKGYSVKSDIWSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADK---FSA
240 250 260 270 280
340 350 360 370 380 390
pF1KB6 SFINFVNLCLTKDESKRPKYKELLKHPFILMYEERAVEVACYVCKILDQMPATPSSPMYV
:..:.. :: :. ..:: : ::..:::. ..: ....:: .: ::
XP_011 EFVDFTSQCLKKNSKERPTYPELMQHPFFTLHESKGTDVASFVKLILGD
290 300 310 320 330
pF1KB6 D
>>XP_006722038 (OMIM: 601254) dual specificity mitogen-a (278 aa)
initn: 1173 init1: 586 opt: 1166 Z-score: 494.9 bits: 99.9 E(92320): 8.6e-21
Smith-Waterman score: 1166; 59.9% identity (82.8% similar) in 279 aa overlap (107-385:2-276)
80 90 100 110 120 130
pF1KB6 RTHSIESSGKLKISPEQHWDFTAEDLKDLGEIGRGAYGSVNKMVHKPSGQIMAVKRIRST
:.:::::: :.:: : ::::::::::::.:
XP_006 MELGRGAYGVVEKMRHVPSGQIMAVKRIRAT
10 20 30
140 150 160 170 180 190
pF1KB6 VDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALFREGDCWICMELMSTSFDKFYKYVYSVL
:. .:::.::::::. ::. :::. : :::::::::: :::::::.::.::::: : .
XP_006 VNSQEQKRLLMDLDISMRTVDCPFTVTFYGALFREGDVWICMELMDTSLDKFYKQVIDK-
40 50 60 70 80 90
200 210 220 230 240 250
pF1KB6 DDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNILLDRSGNIKLCDFGISGQLVD
..:::.:::::... ::::.::. .:..::::.::::.:.. :..:.::::::: :::
XP_006 GQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDVKPSNVLINALGQVKMCDFGISGYLVD
100 110 120 130 140 150
260 270 280 290 300 310
pF1KB6 SIAKTRDAGCRPYMAPERIDPSASRQGYDVRSDVWSLGITLYELATGRFPYPKWNSVFDQ
:.::: ::::.::::::::.: ...::.:.::.::::::. ::: :::: .:.. :.:
XP_006 SVAKTIDAGCKPYMAPERINPELNQKGYSVKSDIWSLGITMIELAILRFPYDSWGTPFQQ
160 170 180 190 200 210
320 330 340 350 360 370
pF1KB6 LTQVVKGDPPQLSNSEEREFSPSFINFVNLCLTKDESKRPKYKELLKHPFILMYEERAVE
: :::. ::: .. :: :..:.. :: :. ..:: : ::..:::. ..: ....
XP_006 LKQVVEEPSPQLPADK---FSAEFVDFTSQCLKKNSKERPTYPELMQHPFFTLHESKGTD
220 230 240 250 260
380 390
pF1KB6 VACYVCKILDQMPATPSSPMYVD
:: .: ::
XP_006 VASFVKLILGD
270
>>NP_001317379 (OMIM: 601254) dual specificity mitogen-a (278 aa)
initn: 1173 init1: 586 opt: 1166 Z-score: 494.9 bits: 99.9 E(92320): 8.6e-21
Smith-Waterman score: 1166; 59.9% identity (82.8% similar) in 279 aa overlap (107-385:2-276)
80 90 100 110 120 130
pF1KB6 RTHSIESSGKLKISPEQHWDFTAEDLKDLGEIGRGAYGSVNKMVHKPSGQIMAVKRIRST
:.:::::: :.:: : ::::::::::::.:
NP_001 MELGRGAYGVVEKMRHVPSGQIMAVKRIRAT
10 20 30
140 150 160 170 180 190
pF1KB6 VDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALFREGDCWICMELMSTSFDKFYKYVYSVL
:. .:::.::::::. ::. :::. : :::::::::: :::::::.::.::::: : .
NP_001 VNSQEQKRLLMDLDISMRTVDCPFTVTFYGALFREGDVWICMELMDTSLDKFYKQVIDK-
40 50 60 70 80 90
200 210 220 230 240 250
pF1KB6 DDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNILLDRSGNIKLCDFGISGQLVD
..:::.:::::... ::::.::. .:..::::.::::.:.. :..:.::::::: :::
NP_001 GQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDVKPSNVLINALGQVKMCDFGISGYLVD
100 110 120 130 140 150
260 270 280 290 300 310
pF1KB6 SIAKTRDAGCRPYMAPERIDPSASRQGYDVRSDVWSLGITLYELATGRFPYPKWNSVFDQ
:.::: ::::.::::::::.: ...::.:.::.::::::. ::: :::: .:.. :.:
NP_001 SVAKTIDAGCKPYMAPERINPELNQKGYSVKSDIWSLGITMIELAILRFPYDSWGTPFQQ
160 170 180 190 200 210
320 330 340 350 360 370
pF1KB6 LTQVVKGDPPQLSNSEEREFSPSFINFVNLCLTKDESKRPKYKELLKHPFILMYEERAVE
: :::. ::: .. :: :..:.. :: :. ..:: : ::..:::. ..: ....
NP_001 LKQVVEEPSPQLPADK---FSAEFVDFTSQCLKKNSKERPTYPELMQHPFFTLHESKGTD
220 230 240 250 260
380 390
pF1KB6 VACYVCKILDQMPATPSSPMYVD
:: .: ::
NP_001 VASFVKLILGD
270
399 residues in 1 query sequences
64369986 residues in 92320 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Oct 24 21:46:21 2019 done: Thu Oct 24 21:46:22 2019
Total Scan time: 4.560 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]