Result of FASTA (omim) for
pFN21AE1872
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1872, 393 aa
1>>>pF1KE1872 393 - 393 aa - 393 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.9719+/-0.000294; mu= 10.7924+/- 0.018
mean_var=125.7693+/-25.457, 0's: 0 Z-trim(121.8): 41 B-trim: 1249 in 1/53
Lambda= 0.114363
statistics sampled from 38842 (38889) to 38842 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.791), E-opt: 0.2 (0.456), width: 16
Scan time: 9.110
The best scores are: opt bits E(85289)
NP_006075 (OMIM: 147574) interferon regulatory fac ( 393) 2687 453.9 3.1e-127
NP_002154 (OMIM: 601565,614893,614894) interferon ( 426) 679 122.6 1.8e-27
XP_006715153 (OMIM: 601900,611724) PREDICTED: inte ( 415) 529 97.8 4.9e-20
NP_001182215 (OMIM: 601900,611724) interferon regu ( 450) 529 97.9 5.2e-20
NP_002451 (OMIM: 601900,611724) interferon regulat ( 451) 529 97.9 5.2e-20
NP_006138 (OMIM: 119300,119500,607199,608864) inte ( 467) 403 77.1 9.7e-14
XP_011514465 (OMIM: 607218,612245,612251) PREDICTE ( 488) 369 71.5 4.9e-12
XP_011514466 (OMIM: 607218,612245,612251) PREDICTE ( 488) 369 71.5 4.9e-12
XP_011514464 (OMIM: 607218,612245,612251) PREDICTE ( 488) 369 71.5 4.9e-12
NP_001092100 (OMIM: 607218,612245,612251) interfer ( 498) 369 71.5 5e-12
NP_116032 (OMIM: 607218,612245,612251) interferon ( 498) 369 71.5 5e-12
NP_001092097 (OMIM: 607218,612245,612251) interfer ( 498) 369 71.5 5e-12
XP_005250374 (OMIM: 607218,612245,612251) PREDICTE ( 514) 368 71.3 5.7e-12
XP_011514462 (OMIM: 607218,612245,612251) PREDICTE ( 514) 368 71.3 5.7e-12
XP_011514461 (OMIM: 607218,612245,612251) PREDICTE ( 514) 368 71.3 5.7e-12
NP_001092099 (OMIM: 607218,612245,612251) interfer ( 514) 368 71.3 5.7e-12
XP_006716037 (OMIM: 607218,612245,612251) PREDICTE ( 514) 368 71.3 5.7e-12
XP_011514460 (OMIM: 607218,612245,612251) PREDICTE ( 514) 368 71.3 5.7e-12
XP_011514463 (OMIM: 607218,612245,612251) PREDICTE ( 504) 366 71.0 7.1e-12
NP_001229381 (OMIM: 607218,612245,612251) interfer ( 412) 362 70.3 9.6e-12
XP_011541680 (OMIM: 147575,211980,613659) PREDICTE ( 284) 351 68.4 2.5e-11
NP_002189 (OMIM: 147575,211980,613659) interferon ( 325) 351 68.4 2.8e-11
NP_002190 (OMIM: 147576) interferon regulatory fac ( 349) 344 67.3 6.6e-11
XP_016882256 (OMIM: 603734,616532) PREDICTED: inte ( 427) 339 66.5 1.4e-10
XP_016882255 (OMIM: 603734,616532) PREDICTED: inte ( 427) 339 66.5 1.4e-10
NP_001562 (OMIM: 603734,616532) interferon regulat ( 427) 339 66.5 1.4e-10
NP_001184053 (OMIM: 603734,616532) interferon regu ( 300) 284 57.3 5.6e-08
XP_006723261 (OMIM: 603734,616532) PREDICTED: inte ( 452) 286 57.8 6.1e-08
NP_001184051 (OMIM: 603734,616532) interferon regu ( 452) 286 57.8 6.1e-08
XP_006723260 (OMIM: 603734,616532) PREDICTED: inte ( 452) 286 57.8 6.1e-08
XP_011518368 (OMIM: 605047,616345) PREDICTED: inte ( 502) 226 47.9 6.4e-05
NP_004020 (OMIM: 605047,616345) interferon regulat ( 474) 225 47.7 6.8e-05
NP_001563 (OMIM: 605047,616345) interferon regulat ( 503) 225 47.7 7.1e-05
XP_005252964 (OMIM: 605047,616345) PREDICTED: inte ( 515) 225 47.8 7.3e-05
XP_005252966 (OMIM: 605047,616345) PREDICTED: inte ( 487) 224 47.6 7.8e-05
NP_004022 (OMIM: 605047,616345) interferon regulat ( 516) 224 47.6 8.2e-05
XP_005252963 (OMIM: 605047,616345) PREDICTED: inte ( 516) 224 47.6 8.2e-05
XP_016878688 (OMIM: 601565,614893,614894) PREDICTE ( 222) 214 45.7 0.00013
NP_001193625 (OMIM: 119300,119500,607199,608864) i ( 372) 212 45.5 0.00025
NP_001184052 (OMIM: 603734,616532) interferon regu ( 392) 186 41.2 0.0051
>>NP_006075 (OMIM: 147574) interferon regulatory factor (393 aa)
initn: 2687 init1: 2687 opt: 2687 Z-score: 2405.3 bits: 453.9 E(85289): 3.1e-127
Smith-Waterman score: 2687; 99.7% identity (100.0% similar) in 393 aa overlap (1-393:1-393)
10 20 30 40 50 60
pF1KE1 MASGRARCTRKLRNWVVEQVESGQFPGVCWDDTAKTMFRIPWKHAGKQDFREDQDAAFFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MASGRARCTRKLRNWVVEQVESGQFPGVCWDDTAKTMFRIPWKHAGKQDFREDQDAAFFK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 AWAIFKGKYKEGDTGGPAVWKTRLRCALNKSSEFKEVPERGRMDVAEPYKVYQLLPPGIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 AWAIFKGKYKEGDTGGPAVWKTRLRCALNKSSEFKEVPERGRMDVAEPYKVYQLLPPGIV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 SGQPGTQKVPSKRQQSSVSSERKEEEDAMQNCTLSPSVLQDSLNNEEEGASGGAVHSDIG
::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::
NP_006 SGQPGTQKVPSKRQHSSVSSERKEEEDAMQNCTLSPSVLQDSLNNEEEGASGGAVHSDIG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 SSSSSSSPEPQEVTDTTEAPFQGDQRSLEFLLPPEPDYSLLLTFIYNGRVVGEAQVQSLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 SSSSSSSPEPQEVTDTTEAPFQGDQRSLEFLLPPEPDYSLLLTFIYNGRVVGEAQVQSLD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 CRLVAEPSGSESSMEQVLFPKPGPLEPTQRLLSQLERGILVASNPRGLFVQRLCPIPISW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 CRLVAEPSGSESSMEQVLFPKPGPLEPTQRLLSQLERGILVASNPRGLFVQRLCPIPISW
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 NAPQAPPGPGPHLLPSNECVELFRTAYFCRDLVRYFQGLGPPPKFQVTLNFWEESHGSSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 NAPQAPPGPGPHLLPSNECVELFRTAYFCRDLVRYFQGLGPPPKFQVTLNFWEESHGSSH
310 320 330 340 350 360
370 380 390
pF1KE1 TPQNLITVKMEQAFARYLLEQTPEQQAAILSLV
:::::::::::::::::::::::::::::::::
NP_006 TPQNLITVKMEQAFARYLLEQTPEQQAAILSLV
370 380 390
>>NP_002154 (OMIM: 601565,614893,614894) interferon regu (426 aa)
initn: 729 init1: 525 opt: 679 Z-score: 614.3 bits: 122.6 E(85289): 1.8e-27
Smith-Waterman score: 740; 34.3% identity (64.9% similar) in 396 aa overlap (10-388:8-387)
10 20 30 40 50 60
pF1KE1 MASGRARCTRKLRNWVVEQVESGQFPGVCWDDTAKTMFRIPWKHAGKQDFREDQDAAFFK
:.::.:..::..:...::. :.. :.:::::::::::::. .. ::..::
NP_002 MCDRNGGRRLRQWLIEQIDSSMYPGLIWENEEKSMFRIPWKHAGKQDYNQEVDASIFK
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 AWAIFKGKYKEGDTGGPAVWKTRLRCALNKSSEFKEVPERGRMDVAEPYKVYQLLPPGIV
:::.::::.:::: . ::.:::::::::::: .:.:: .:...:..::::::...:
NP_002 AWAVFKGKFKEGDKAEPATWKTRLRCALNKSPDFEEVTDRSQLDISEPYKVYRIVPEEEQ
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE1 SGQPGTQKVPSKRQQSSVSSERKEEEDAMQNCTLSPSVLQDSLNNEEEGASGGAVHSDIG
. . :. . . . . :.: .. ... ::: .: .. ... :
NP_002 KCKLGVATAGCVNEVTEMECGRSEIDELIKE----PSV-DDYMGMIKRSPSPPE------
120 130 140 150 160
190 200 210 220 230
pF1KE1 SSSSSSSPEPQEVTDTTEAPFQGDQRSLEFLLPPEPDYS-LLLTFIYNGRVVGEAQVQSL
. :. :. .: .:. . . . .: ....: :.:..::.: .
NP_002 ACRSQLLPDWWAQQPSTGVPLVTGYTTYD---AHHSAFSQMVISFYYGGKLVGQATTTCP
170 180 190 200 210 220
240 250 260 270 280
pF1KE1 D-CRL-VAEPS--GSE----SSMEQVLFPKPGPLEPTQR-------LLSQLERGILVASN
. ::: ...:. :.. ..: : :: :. :..: :...::::.:. :.
NP_002 EGCRLSLSQPGLPGTKLYGPEGLELVRFP-PADAIPSERQRQVTRKLFGHLERGVLLHSS
230 240 250 260 270 280
290 300 310 320 330 340
pF1KE1 PRGLFVQRLCPIPISWNAPQAPPGPG-PHLLPSNECVELFRTAYFCRDLVRYFQGLGPPP
.:.::.::: . . . .: : :. : .: :..: :. : :.: ..... : :
NP_002 RQGVFVKRLCQGRV-FCSGNAVVCKGRPNKLERDEVVQVFDTSQFFRELQQFYNSQGRLP
290 300 310 320 330 340
350 360 370 380 390
pF1KE1 KFQVTLNFWEESHGSSHTPQNLITVKMEQAFARYLLEQTPEQQAAILSLV
.:.: : :: . ..:: :..:: ..: : :.. .. .:
NP_002 DGRVVLCFGEEFPDMAPLRSKLILVQIEQLYVRQLAEEAGKSCGAGSVMQAPEEPPPDQV
350 360 370 380 390 400
NP_002 FRMFPDICASHQRSFFRENQQITV
410 420
>>XP_006715153 (OMIM: 601900,611724) PREDICTED: interfer (415 aa)
initn: 754 init1: 328 opt: 529 Z-score: 480.7 bits: 97.8 E(85289): 4.9e-20
Smith-Waterman score: 757; 35.6% identity (62.3% similar) in 374 aa overlap (11-378:23-377)
10 20 30 40
pF1KE1 MASGRARCTRKLRNWVVEQVESGQFPGVCWDDTAKTMFRIPWKHAGKQ
:::.:...:..::..::. :.. :..:::::::::::
XP_006 MNLEGGGRGGEFGMSAVSCGNGKLRQWLIDQIDSGKYPGLVWENEEKSIFRIPWKHAGKQ
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE1 DFREDQDAAFFKAWAIFKGKYKEG-DTGGPAVWKTRLRCALNKSSEFKEVPERGRMDVAE
:. ...:::.:::::.::::..:: : : .::::::::::::..:.:. ::...:...
XP_006 DYNREEDAALFKAWALFKGKFREGIDKPDPPTWKTRLRCALNKSNDFEELVERSQLDISD
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE1 PYKVYQLLPPGIVSGQPGTQKVPSKRQQSSVSSERKEEEDAMQNCTLSPSVLQDSLNNEE
:::::...: : .. :.... . : :.: . : ::. ....:
XP_006 PYKVYRIVPEG---AKKGAKQLTLEDPQMSMSHP-------YTMTTPYPSLPAQQVHNY-
130 140 150 160
170 180 190 200 210 220
pF1KE1 EGASGGAVHSDIGSSSSSSSPEPQEVTDTTEAPFQGDQRSLEFLLPP-EPDYSLLLTFIY
. . : . :. . . :. :. .. : : : : . . :
XP_006 -------MMPPLDRSWRDYVPDQPHPEIPYQCPMTFGPRGHHWQGPACENDCRLHICLYY
170 180 190 200 210 220
230 240 250 260 270 280
pF1KE1 NGRVVGEAQVQSLD-CRLVAEPSGSESSMEQVLFPKP---GPLEPTQRLLSQLERGILVA
.: : ..: . ::. . . :...::::: : : . ..:::.::::...
XP_006 REILVKELTTSSPEGCRISHGHTYDASNLDQVLFPYPEDNGQRKNIEKLLSHLERGVVLW
230 240 250 260 270 280
290 300 310 320 330 340
pF1KE1 SNPRGLFVQRLCPIPISWNAPQAPPGPGPHLLPSNECVELFRTAYFCRDLVRYFQGLGPP
: ::...::: : :..: : . :. : .. .:: : : .: . .
XP_006 MAPDGLYAKRLCQSRIYWDGPLALCNDRPNKLERDQTCKLFDTQQFLSELQAFAHHGRSL
290 300 310 320 330 340
350 360 370 380 390
pF1KE1 PKFQVTLNFWEESHGSSHTPQNLITVKMEQAFARYLLEQTPEQQAAILSLV
:.::::: : :: . . ..:::...: .:: :
XP_006 PRFQVTLCFGEE-FPDPQRQRKLITAHVEPLLARQLYYFAQQNSGHFLRGYDLPEHISNP
350 360 370 380 390 400
XP_006 EDYHRSIRHSSIQE
410
>>NP_001182215 (OMIM: 601900,611724) interferon regulato (450 aa)
initn: 741 init1: 328 opt: 529 Z-score: 480.2 bits: 97.9 E(85289): 5.2e-20
Smith-Waterman score: 740; 34.8% identity (61.4% similar) in 394 aa overlap (11-378:23-412)
10 20 30 40
pF1KE1 MASGRARCTRKLRNWVVEQVESGQFPGVCWDDTAKTMFRIPWKHAGKQ
:::.:...:..::..::. :.. :..:::::::::::
NP_001 MNLEGGGRGGEFGMSAVSCGNGKLRQWLIDQIDSGKYPGLVWENEEKSIFRIPWKHAGKQ
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE1 DFREDQDAAFFKAWAIFKGKYKEG-DTGGPAVWKTRLRCALNKSSEFKEVPERGRMDVAE
:. ...:::.:::::.::::..:: : : .::::::::::::..:.:. ::...:...
NP_001 DYNREEDAALFKAWALFKGKFREGIDKPDPPTWKTRLRCALNKSNDFEELVERSQLDISD
70 80 90 100 110 120
110 120 130 140 150
pF1KE1 PYKVYQLLPPGIVSG-QPGTQKVP--SKRQQSSVSSERKEEEDAMQNCTLSP------SV
:::::...: : .: . : . : : . .... ..: . : .
NP_001 PYKVYRIVPEGAKKGAKQLTLEDPQMSMSHPYTMTTPYPSLPAQVHNYMMPPLDRSWRDY
130 140 150 160 170 180
160 170 180 190 200
pF1KE1 LQDSLNNE----------EEGA--SGGAVHSDIGSSSSSSSPEPQEVTDTTEAPFQGDQR
. :. . : .: .: : .. ... . : : ... .: . . :
NP_001 VPDQPHPEIPYQCPMTFGPRGHHWQGPACENGCQVTGTFYACAPPE-SQAPGVPTEPSIR
190 200 210 220 230
210 220 230 240 250 260
pF1KE1 SLEFLLPPEPDYSLLLTFIYNGRVVGEAQVQSLD-CRLVAEPSGSESSMEQVLFPKP---
: : : : : . . : .: : ..: . ::. . . :...::::: :
NP_001 SAEAL--AFSDCRLHICLYYREILVKELTTSSPEGCRISHGHTYDASNLDQVLFPYPEDN
240 250 260 270 280 290
270 280 290 300 310 320
pF1KE1 GPLEPTQRLLSQLERGILVASNPRGLFVQRLCPIPISWNAPQAPPGPGPHLLPSNECVEL
: . ..:::.::::... : ::...::: : :..: : . :. : .. .:
NP_001 GQRKNIEKLLSHLERGVVLWMAPDGLYAKRLCQSRIYWDGPLALCNDRPNKLERDQTCKL
300 310 320 330 340 350
330 340 350 360 370 380
pF1KE1 FRTAYFCRDLVRYFQGLGPPPKFQVTLNFWEESHGSSHTPQNLITVKMEQAFARYLLEQT
: : : .: . . :.::::: : :: . . ..:::...: .:: :
NP_001 FDTQQFLSELQAFAHHGRSLPRFQVTLCFGEE-FPDPQRQRKLITAHVEPLLARQLYYFA
360 370 380 390 400 410
390
pF1KE1 PEQQAAILSLV
NP_001 QQNSGHFLRGYDLPEHISNPEDYHRSIRHSSIQE
420 430 440 450
>>NP_002451 (OMIM: 601900,611724) interferon regulatory (451 aa)
initn: 741 init1: 328 opt: 529 Z-score: 480.2 bits: 97.9 E(85289): 5.2e-20
Smith-Waterman score: 734; 34.9% identity (61.1% similar) in 398 aa overlap (11-378:23-413)
10 20 30 40
pF1KE1 MASGRARCTRKLRNWVVEQVESGQFPGVCWDDTAKTMFRIPWKHAGKQ
:::.:...:..::..::. :.. :..:::::::::::
NP_002 MNLEGGGRGGEFGMSAVSCGNGKLRQWLIDQIDSGKYPGLVWENEEKSIFRIPWKHAGKQ
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE1 DFREDQDAAFFKAWAIFKGKYKEG-DTGGPAVWKTRLRCALNKSSEFKEVPERGRMDVAE
:. ...:::.:::::.::::..:: : : .::::::::::::..:.:. ::...:...
NP_002 DYNREEDAALFKAWALFKGKFREGIDKPDPPTWKTRLRCALNKSNDFEELVERSQLDISD
70 80 90 100 110 120
110 120 130 140 150
pF1KE1 PYKVYQLLPPGIVSGQPGTQKVPSKRQQSSVSSERKEEED-----AMQ--NCTLSP----
:::::...: : .. :.... . : :.: :.: : . :
NP_002 PYKVYRIVPEG---AKKGAKQLTLEDPQMSMSHPYTMTTPYPSLPAQQVHNYMMPPLDRS
130 140 150 160 170
160 170 180 190 200
pF1KE1 --SVLQDSLNNE----------EEGA--SGGAVHSDIGSSSSSSSPEPQEVTDTTEAPFQ
. . :. . : .: .: : .. ... . : : ... .: .
NP_002 WRDYVPDQPHPEIPYQCPMTFGPRGHHWQGPACENGCQVTGTFYACAPPE-SQAPGVPTE
180 190 200 210 220 230
210 220 230 240 250 260
pF1KE1 GDQRSLEFLLPPEPDYSLLLTFIYNGRVVGEAQVQSLD-CRLVAEPSGSESSMEQVLFPK
. :: : : : : . . : .: : ..: . ::. . . :...:::::
NP_002 PSIRSAEAL--AFSDCRLHICLYYREILVKELTTSSPEGCRISHGHTYDASNLDQVLFPY
240 250 260 270 280 290
270 280 290 300 310
pF1KE1 P---GPLEPTQRLLSQLERGILVASNPRGLFVQRLCPIPISWNAPQAPPGPGPHLLPSNE
: : . ..:::.::::... : ::...::: : :..: : . :. : ..
NP_002 PEDNGQRKNIEKLLSHLERGVVLWMAPDGLYAKRLCQSRIYWDGPLALCNDRPNKLERDQ
300 310 320 330 340 350
320 330 340 350 360 370
pF1KE1 CVELFRTAYFCRDLVRYFQGLGPPPKFQVTLNFWEESHGSSHTPQNLITVKMEQAFARYL
.:: : : .: . . :.::::: : :: . . ..:::...: .:: :
NP_002 TCKLFDTQQFLSELQAFAHHGRSLPRFQVTLCFGEE-FPDPQRQRKLITAHVEPLLARQL
360 370 380 390 400 410
380 390
pF1KE1 LEQTPEQQAAILSLV
NP_002 YYFAQQNSGHFLRGYDLPEHISNPEDYHRSIRHSSIQE
420 430 440 450
>>NP_006138 (OMIM: 119300,119500,607199,608864) interfer (467 aa)
initn: 490 init1: 222 opt: 403 Z-score: 367.6 bits: 77.1 E(85289): 9.7e-14
Smith-Waterman score: 595; 31.2% identity (58.6% similar) in 401 aa overlap (11-380:9-404)
10 20 30 40 50 60
pF1KE1 MASGRARCTRKLRNWVVEQVESGQFPGVCWDDTAKTMFRIPWKHAGKQDFREDQDAAFFK
.:. :.: ::.:: .::. : . :.:::::: ... ..... ..::
NP_006 MALHPRRVRLKPWLVAQVDSGLYPGLIWLHRDSKRFQIPWKHATRHSPQQEEENTIFK
10 20 30 40 50
70 80 90 100 110
pF1KE1 AWAIFKGKYKEG-DTGGPAVWKTRLRCALNKSSEFKEVPERGRMDVAEPYKVYQLL----
:::. :::.:: : :: ::..:::::::: ::. . . . .: :.::.
NP_006 AWAVETGKYQEGVDDPDPAKWKAQLRCALNKSREFNLMYDGTKEVPMNPVKIYQVCDIPQ
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 PPGIVSGQPGTQKVPSKRQQSSVSSERKEEE-DAMQNCTLSPSVLQDS---LN-NEEEGA
: : . . .: ..: .....:. : .:.: : :. . : .::. :: : :
NP_006 PQGSIINPGSTGSAPWDEKDNDVDEEDEEDELDQSQHHV--P--IQDTFPFLNINGSPMA
120 130 140 150 160 170
180 190 200 210 220
pF1KE1 SGGAVHSDIGSSSSSS---SPEPQEVTDTTEAPFQGDQRSLEFLLPPEPDYSLLLTFIYN
... . ..:. : . . :: :. .. .::.: : :. . : .: . : :
NP_006 PASVGNCSVGNCSPEAVWPKTEPLEM-EVPQAPIQPFYSSPELWISSLPMTDLDIKFQYR
180 190 200 210 220 230
230 240 250 260 270
pF1KE1 GRVVGEAQVQS--LDCRLV-----AEPSGSE----SSMEQVLFPKPGPLEP------TQR
:. :.... : ::: :. : :.::: :: : . :..
NP_006 GKEYGQTMTVSNPQGCRLFYGDLGPMPDQEELFGPVSLEQVKFPGPEHITNEKQKLFTSK
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE1 LLSQLERGILVASNPRGLFVQRLCPIPISWNAPQAPPGPGPHLLPSNECVELFRTAYFCR
::. ..::... . ..... ::: . :..: :: .:.:. .. :.:: :
NP_006 LLDVMDRGLILEVSGHAIYAIRLCQCKVYWSGPCAPSLVAPNLIERQKKVKLFCLETFLS
300 310 320 330 340 350
340 350 360 370 380
pF1KE1 DLVRYFQG-LGPPPKFQVTLNFWEESHGSSHTPQNLITVKMEQAFARYLLEQTPEQQAAI
::. . .: . : :.. : : :: .. ..:: :.. . ::.. :
NP_006 DLIAHQKGQIEKQPPFEIYLCFGEEWPDGKPLERKLILVQVIPVVARMIYEMFSGDFTRS
360 370 380 390 400 410
390
pF1KE1 LSLV
NP_006 FDSGSVRLQISTPDIKDNIVAQLKQLYRILQTQESWQPMQPTPSMQLPPALPPQ
420 430 440 450 460
>>XP_011514465 (OMIM: 607218,612245,612251) PREDICTED: i (488 aa)
initn: 509 init1: 218 opt: 369 Z-score: 337.0 bits: 71.5 E(85289): 4.9e-12
Smith-Waterman score: 529; 29.4% identity (53.7% similar) in 408 aa overlap (11-380:16-418)
10 20 30 40 50
pF1KE1 MASGRARCTRKLRNWVVEQVESGQFPGVCWDDTAKTMFRIPWKHAGKQDFREDQD
.:. :.: ::.: :.::. : . : .: :::.:: .. .: :
XP_011 MNQSIPVAPTPPRRVRLKPWLVAQVNSCQYPGLQWVNGEKKLFCIPWRHATRHGPSQDGD
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 AAFFKAWAIFKGKYKEG-DTGGPAVWKTRLRCALNKSSEFKEVPERGRMDVAEPYKVYQL
..::::: ::: :: : . :: ::. :::::::: .:. . . : .:::.:.
XP_011 NTIFKAWAKETGKYTEGVDEADPAKWKANLRCALNKSRDFRLIYDGPRDMPPQPYKIYE-
70 80 90 100 110
120 130 140 150 160 170
pF1KE1 LPPGIVSGQPGTQKVPSKRQQSSVSSERKEEEDAMQNCTLSPSVLQDSL---NNEEEGAS
. :. :. .. : ..:..:::. .: : :. .: . . .
XP_011 ----VCSNGPAPTDSQPPEDYSFGAGEEEEEEEELQRMLPSLSLTEDVKWPPTLQPPTLQ
120 130 140 150 160 170
180 190 200 210
pF1KE1 GGAVHSDIGSSSSSSSPEP-------QEVTDTTEA-------PFQGDQRSLEFLLPPE--
.: . . . : .: : . .... : : :.: ..:. :.
XP_011 PPVVLGPPAPDPSPLAPPPGNPAGFRELLSEVLEPGPLPASLPPAGEQLLPDLLISPHML
180 190 200 210 220 230
220 230 240 250 260
pF1KE1 PDYSLLLTFIYNGRVVGEAQVQS-LDCRLVA---EPSGSES------SMEQVLFPKPGPL
: .: . : : :: ... ::: : . . :.::: ::.: .
XP_011 PLTDLEIKFQYRGRPPRALTISNPHGCRLFYSQLEATQEQVELFGPISLEQVRFPSPEDI
240 250 260 270 280 290
270 280 290 300 310
pF1KE1 EP------TQRLLSQLERGILVASNPRGLFVQRLCPIPISWNAPQAPPGPG-PHLLPSNE
:..::. :.::... . . :.. ::: . :..: : . :. . .
XP_011 PSDKQRFYTNQLLDVLDRGLILQLQGQDLYAIRLCQCKVFWSGPCASAHDSCPNPIQREV
300 310 320 330 340 350
320 330 340 350 360 370
pF1KE1 CVELFRTAYFCRDLVRYFQG-LGPPPKFQVTLNFWEESHGSSHTPQNLITVKMEQAFARY
..:: .: .:. . .: . :: :.. . : :: . ..::::.. . ::
XP_011 KTKLFSLEHFLNELILFQKGQTNTPPPFEIFFCFGEEWPDRKPREKKLITVQVVPVAARL
360 370 380 390 400 410
380 390
pF1KE1 LLEQTPEQQAAILSLV
:::
XP_011 LLEMFSGELSWSADSIRLQISNPDLKDRMVEQFKELHHIWQSQQRLQPVAQAPPGAGLGV
420 430 440 450 460 470
>>XP_011514466 (OMIM: 607218,612245,612251) PREDICTED: i (488 aa)
initn: 509 init1: 218 opt: 369 Z-score: 337.0 bits: 71.5 E(85289): 4.9e-12
Smith-Waterman score: 529; 29.4% identity (53.7% similar) in 408 aa overlap (11-380:16-418)
10 20 30 40 50
pF1KE1 MASGRARCTRKLRNWVVEQVESGQFPGVCWDDTAKTMFRIPWKHAGKQDFREDQD
.:. :.: ::.: :.::. : . : .: :::.:: .. .: :
XP_011 MNQSIPVAPTPPRRVRLKPWLVAQVNSCQYPGLQWVNGEKKLFCIPWRHATRHGPSQDGD
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 AAFFKAWAIFKGKYKEG-DTGGPAVWKTRLRCALNKSSEFKEVPERGRMDVAEPYKVYQL
..::::: ::: :: : . :: ::. :::::::: .:. . . : .:::.:.
XP_011 NTIFKAWAKETGKYTEGVDEADPAKWKANLRCALNKSRDFRLIYDGPRDMPPQPYKIYE-
70 80 90 100 110
120 130 140 150 160 170
pF1KE1 LPPGIVSGQPGTQKVPSKRQQSSVSSERKEEEDAMQNCTLSPSVLQDSL---NNEEEGAS
. :. :. .. : ..:..:::. .: : :. .: . . .
XP_011 ----VCSNGPAPTDSQPPEDYSFGAGEEEEEEEELQRMLPSLSLTEDVKWPPTLQPPTLQ
120 130 140 150 160 170
180 190 200 210
pF1KE1 GGAVHSDIGSSSSSSSPEP-------QEVTDTTEA-------PFQGDQRSLEFLLPPE--
.: . . . : .: : . .... : : :.: ..:. :.
XP_011 PPVVLGPPAPDPSPLAPPPGNPAGFRELLSEVLEPGPLPASLPPAGEQLLPDLLISPHML
180 190 200 210 220 230
220 230 240 250 260
pF1KE1 PDYSLLLTFIYNGRVVGEAQVQS-LDCRLVA---EPSGSES------SMEQVLFPKPGPL
: .: . : : :: ... ::: : . . :.::: ::.: .
XP_011 PLTDLEIKFQYRGRPPRALTISNPHGCRLFYSQLEATQEQVELFGPISLEQVRFPSPEDI
240 250 260 270 280 290
270 280 290 300 310
pF1KE1 EP------TQRLLSQLERGILVASNPRGLFVQRLCPIPISWNAPQAPPGPG-PHLLPSNE
:..::. :.::... . . :.. ::: . :..: : . :. . .
XP_011 PSDKQRFYTNQLLDVLDRGLILQLQGQDLYAIRLCQCKVFWSGPCASAHDSCPNPIQREV
300 310 320 330 340 350
320 330 340 350 360 370
pF1KE1 CVELFRTAYFCRDLVRYFQG-LGPPPKFQVTLNFWEESHGSSHTPQNLITVKMEQAFARY
..:: .: .:. . .: . :: :.. . : :: . ..::::.. . ::
XP_011 KTKLFSLEHFLNELILFQKGQTNTPPPFEIFFCFGEEWPDRKPREKKLITVQVVPVAARL
360 370 380 390 400 410
380 390
pF1KE1 LLEQTPEQQAAILSLV
:::
XP_011 LLEMFSGELSWSADSIRLQISNPDLKDRMVEQFKELHHIWQSQQRLQPVAQAPPGAGLGV
420 430 440 450 460 470
>>XP_011514464 (OMIM: 607218,612245,612251) PREDICTED: i (488 aa)
initn: 509 init1: 218 opt: 369 Z-score: 337.0 bits: 71.5 E(85289): 4.9e-12
Smith-Waterman score: 529; 29.4% identity (53.7% similar) in 408 aa overlap (11-380:16-418)
10 20 30 40 50
pF1KE1 MASGRARCTRKLRNWVVEQVESGQFPGVCWDDTAKTMFRIPWKHAGKQDFREDQD
.:. :.: ::.: :.::. : . : .: :::.:: .. .: :
XP_011 MNQSIPVAPTPPRRVRLKPWLVAQVNSCQYPGLQWVNGEKKLFCIPWRHATRHGPSQDGD
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 AAFFKAWAIFKGKYKEG-DTGGPAVWKTRLRCALNKSSEFKEVPERGRMDVAEPYKVYQL
..::::: ::: :: : . :: ::. :::::::: .:. . . : .:::.:.
XP_011 NTIFKAWAKETGKYTEGVDEADPAKWKANLRCALNKSRDFRLIYDGPRDMPPQPYKIYE-
70 80 90 100 110
120 130 140 150 160 170
pF1KE1 LPPGIVSGQPGTQKVPSKRQQSSVSSERKEEEDAMQNCTLSPSVLQDSL---NNEEEGAS
. :. :. .. : ..:..:::. .: : :. .: . . .
XP_011 ----VCSNGPAPTDSQPPEDYSFGAGEEEEEEEELQRMLPSLSLTEDVKWPPTLQPPTLQ
120 130 140 150 160 170
180 190 200 210
pF1KE1 GGAVHSDIGSSSSSSSPEP-------QEVTDTTEA-------PFQGDQRSLEFLLPPE--
.: . . . : .: : . .... : : :.: ..:. :.
XP_011 PPVVLGPPAPDPSPLAPPPGNPAGFRELLSEVLEPGPLPASLPPAGEQLLPDLLISPHML
180 190 200 210 220 230
220 230 240 250 260
pF1KE1 PDYSLLLTFIYNGRVVGEAQVQS-LDCRLVA---EPSGSES------SMEQVLFPKPGPL
: .: . : : :: ... ::: : . . :.::: ::.: .
XP_011 PLTDLEIKFQYRGRPPRALTISNPHGCRLFYSQLEATQEQVELFGPISLEQVRFPSPEDI
240 250 260 270 280 290
270 280 290 300 310
pF1KE1 EP------TQRLLSQLERGILVASNPRGLFVQRLCPIPISWNAPQAPPGPG-PHLLPSNE
:..::. :.::... . . :.. ::: . :..: : . :. . .
XP_011 PSDKQRFYTNQLLDVLDRGLILQLQGQDLYAIRLCQCKVFWSGPCASAHDSCPNPIQREV
300 310 320 330 340 350
320 330 340 350 360 370
pF1KE1 CVELFRTAYFCRDLVRYFQG-LGPPPKFQVTLNFWEESHGSSHTPQNLITVKMEQAFARY
..:: .: .:. . .: . :: :.. . : :: . ..::::.. . ::
XP_011 KTKLFSLEHFLNELILFQKGQTNTPPPFEIFFCFGEEWPDRKPREKKLITVQVVPVAARL
360 370 380 390 400 410
380 390
pF1KE1 LLEQTPEQQAAILSLV
:::
XP_011 LLEMFSGELSWSADSIRLQISNPDLKDRMVEQFKELHHIWQSQQRLQPVAQAPPGAGLGV
420 430 440 450 460 470
>>NP_001092100 (OMIM: 607218,612245,612251) interferon r (498 aa)
initn: 474 init1: 218 opt: 369 Z-score: 336.9 bits: 71.5 E(85289): 5e-12
Smith-Waterman score: 516; 29.1% identity (53.5% similar) in 413 aa overlap (11-380:16-428)
10 20 30 40 50
pF1KE1 MASGRARCTRKLRNWVVEQVESGQFPGVCWDDTAKTMFRIPWKHAGKQDFREDQD
.:. :.: ::.: :.::. : . : .: :::.:: .. .: :
NP_001 MNQSIPVAPTPPRRVRLKPWLVAQVNSCQYPGLQWVNGEKKLFCIPWRHATRHGPSQDGD
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 AAFFKAWAIFKGKYKEG-DTGGPAVWKTRLRCALNKSSEFKEVPERGRMDVAEPYKVYQL
..::::: ::: :: : . :: ::. :::::::: .:. . . : .:::.:..
NP_001 NTIFKAWAKETGKYTEGVDEADPAKWKANLRCALNKSRDFRLIYDGPRDMPPQPYKIYEV
70 80 90 100 110 120
120 130 140 150 160
pF1KE1 LP--PGIVSGQP--------GTQKVPSKRQQSSVSSERKEEE----DAMQNCTLSPSVLQ
:. ...:: : .. .. : . : :. ..: :: : .::
NP_001 CSNGPAPTDSQPPEDYSFGAGEEEEEEEELQRMLPSLSLTEDVKWPPTLQPPTLRPPTLQ
130 140 150 160 170 180
170 180 190 200 210
pF1KE1 D-SLNNEEEGASGGAVHSDIGSSSSSSSPEPQEVTDTTEA-------PFQGDQRSLEFLL
.:. . . : .. .. . . .... : : :.: ..:.
NP_001 PPTLQPPVVLGPPAPDPSPLAPPPGNPAGFRELLSEVLEPGPLPASLPPAGEQLLPDLLI
190 200 210 220 230 240
220 230 240 250 260
pF1KE1 PPE--PDYSLLLTFIYNGRVVGEAQVQS-LDCRLVA---EPSGSES------SMEQVLFP
:. : .: . : : :: ... ::: : . . :.::: ::
NP_001 SPHMLPLTDLEIKFQYRGRPPRALTISNPHGCRLFYSQLEATQEQVELFGPISLEQVRFP
250 260 270 280 290 300
270 280 290 300 310
pF1KE1 KPGPLEP------TQRLLSQLERGILVASNPRGLFVQRLCPIPISWNAPQAPPGPG-PHL
.: . :..::. :.::... . . :.. ::: . :..: : . :.
NP_001 SPEDIPSDKQRFYTNQLLDVLDRGLILQLQGQDLYAIRLCQCKVFWSGPCASAHDSCPNP
310 320 330 340 350 360
320 330 340 350 360 370
pF1KE1 LPSNECVELFRTAYFCRDLVRYFQG-LGPPPKFQVTLNFWEESHGSSHTPQNLITVKMEQ
. . ..:: .: .:. . .: . :: :.. . : :: . ..::::..
NP_001 IQREVKTKLFSLEHFLNELILFQKGQTNTPPPFEIFFCFGEEWPDRKPREKKLITVQVVP
370 380 390 400 410 420
380 390
pF1KE1 AFARYLLEQTPEQQAAILSLV
. :: :::
NP_001 VAARLLLEMFSGELSWSADSIRLQISNPDLKDRMVEQFKELHHIWQSQQRLQPVAQAPPG
430 440 450 460 470 480
393 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 01:59:03 2016 done: Sun Nov 6 01:59:04 2016
Total Scan time: 9.110 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]