Result of FASTA (ccds) for
pFN21AE4367
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4367, 386 aa
1>>>pF1KE4367 386 - 386 aa - 386 aa
Library: human.CCDS.faa
18921897 residues in 33420 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.6811+/-0.00084; mu= 17.0173+/- 0.051
mean_var=117.1051+/-22.797, 0's: 0 Z-trim(111.1): 36 B-trim: 53 in 1/51
Lambda= 0.118519
statistics sampled from 12213 (12242) to 12213 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.729), E-opt: 0.2 (0.366), width: 16
Scan time: 1.570
The best scores are: opt bits E(33420)
CCDS6038.1 TNFRSF10D gene_id:8793|Hs109|chr8 ( 386) 2571 450.4 1.3e-126
CCDS6035.1 TNFRSF10B gene_id:8795|Hs109|chr8 ( 440) 1090 197.2 2.4e-50
CCDS6037.1 TNFRSF10C gene_id:8794|Hs109|chr8 ( 259) 819 150.6 1.5e-36
CCDS6036.1 TNFRSF10B gene_id:8795|Hs109|chr8 ( 411) 664 124.3 2e-28
CCDS6039.1 TNFRSF10A gene_id:8797|Hs109|chr8 ( 468) 632 118.9 9.6e-27
>>CCDS6038.1 TNFRSF10D gene_id:8793|Hs109|chr8 (386 aa)
initn: 2571 init1: 2571 opt: 2571 Z-score: 2386.7 bits: 450.4 E(33420): 1.3e-126
Smith-Waterman score: 2571; 99.7% identity (99.7% similar) in 386 aa overlap (1-386:1-386)
10 20 30 40 50 60
pF1KE4 MGLWGQSVPTASSARAGRYPGARTASGTRPWLLDPKILKFVVFIVAVLLPVRVDSATIPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS60 MGLWGQSVPTASSARAGRYPGARTASGTRPWLLDPKILKFVVFIVAVLLPVRVDSATIPR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 QDEVPQQTVAPQQQRRSLKEEECPAGSHRSEYTGACNPCTEGVDYTIASNNLPSCLLCTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS60 QDEVPQQTVAPQQQRRSLKEEECPAGSHRSEYTGACNPCTEGVDYTIASNNLPSCLLCTV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 CKSGQTNKSSCTTTRDTVCQCEKGSFQDKNSPEMCRTCRTGCPRGMVKVSNCTPRSDIKC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS60 CKSGQTNKSSCTTTRDTVCQCEKGSFQDKNSPEMCRTCRTGCPRGMVKVSNCTPRSDIKC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 KNESAASSTGKTPAAEETVTTILGMLASPYHYLIIIVVLVIILAVVVVGFSCRKKFISYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS60 KNESAASSTGKTPAAEETVTTILGMLASPYHYLIIIVVLVIILAVVVVGFSCRKKFISYL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 KGICSGGGGGPERVHRVLFRRRSCPSRVPGAEDNARNETLSNRYLQPTQVSEQEIQGQEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS60 KGICSGGGGGPERVHRVLFRRRSCPSRVPGAEDNARNETLSNRYLQPTQVSEQEIQGQEL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 AELTGVTVESPEEPQRLLEQAEAEGCQRRRLLVPVNDADSADISTLLDASATLEEGHAKE
::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS60 AELTGVTVELPEEPQRLLEQAEAEGCQRRRLLVPVNDADSADISTLLDASATLEEGHAKE
310 320 330 340 350 360
370 380
pF1KE4 TIQDQLVGSEKLFYEEDEAGSATSCL
::::::::::::::::::::::::::
CCDS60 TIQDQLVGSEKLFYEEDEAGSATSCL
370 380
>>CCDS6035.1 TNFRSF10B gene_id:8795|Hs109|chr8 (440 aa)
initn: 1035 init1: 582 opt: 1090 Z-score: 1017.4 bits: 197.2 E(33420): 2.4e-50
Smith-Waterman score: 1090; 53.0% identity (71.6% similar) in 345 aa overlap (5-342:5-336)
10 20 30 40 50
pF1KE4 MGLWGQSVPTASSARAGRYPGARTASGTRPWLLDPKILKFVVFIVA-VLLPVRVDSATIP
::..:.::.:: . :: : : :.:: :.. : .:..:: ::: : ..:: :
CCDS60 MEQRGQNAPAASGARKRHGPGPREARGARP---GPRVPKTLVLVVAAVLLLVSAESALIT
10 20 30 40 50
60 70 80 90 100 110
pF1KE4 RQDEVPQQTVAPQQQRRSLKEEECPAGSHRSEYTGACNPCTEGVDYTIASNNLPSCLLCT
.:: .::: .::::.: : .: :: : : :: : : : ::. :.: :: ::
CCDS60 QQDLAPQQRAAPQQKRSSPSEGLCPPGHHISEDGRDCISCKYGQDYSTHWNDLLFCLRCT
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE4 VCKSGQTNKSSCTTTRDTVCQCEKGSFQDKNSPEMCRTCRTGCPRGMVKVSNCTPRSDIK
: ::... : :::::.::::::.:.:....:::::: ::::::::::::..::: :::.
CCDS60 RCDSGEVELSPCTTTRNTVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPWSDIE
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE4 C-KNESAASSTGKTPAAEETVTTILGMLASPYHYL-IIIVVLVIILAVVVVGFSCR----
: ..::... .:..::.:::::. : ::: ::: : : ....:. : :.
CCDS60 CVHKESGTKHSGEVPAVEETVTSSPGTPASPCSLSGIIIGVTVAAVVLIVAVFVCKSLLW
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE4 KKFISYLKGICSGGGGGPERVHRVLFRRRSCPSRVPGAEDNARNETLSNRYLQPTQVSEQ
:: . ::::::::::: :::: : :. ::::::. :: .: :::::: ::
CCDS60 KKVLPYLKGICSGGGGDPERVDR--------SSQRPGAEDNVLNEIVS--ILQPTQVPEQ
240 250 260 270 280
300 310 320 330 340 350
pF1KE4 EIQGQELAELTGVTVESPEEPQRLLEQAEAEGCQRRRLLVPVNDADSADISTLLDASATL
:.. :: :: :::.. :: : ..::: :::: ::::::::.:..: ..
CCDS60 EMEVQEPAEPTGVNMLSPGESEHLLEPAEAERSQRRRLLVPANEGDPTETLRQCFDDFAD
290 300 310 320 330 340
360 370 380
pF1KE4 EEGHAKETIQDQLVGSEKLFYEEDEAGSATSCL
CCDS60 LVPFDSWEPLMRKLGLMDNEIKVAKAEAAGHRDTLYTMLIKWVNKTGRDASVHTLLDALE
350 360 370 380 390 400
>>CCDS6037.1 TNFRSF10C gene_id:8794|Hs109|chr8 (259 aa)
initn: 907 init1: 680 opt: 819 Z-score: 769.8 bits: 150.6 E(33420): 1.5e-36
Smith-Waterman score: 819; 71.2% identity (85.3% similar) in 170 aa overlap (35-204:5-173)
10 20 30 40 50 60
pF1KE4 GQSVPTASSARAGRYPGARTASGTRPWLLDPKILKFVVFIVAVLLPVRVDSATIPRQDEV
:: ::::: :::::::: . ::: ::.::
CCDS60 MARIPKTLKFVVVIVAVLLPVLAYSATTARQEEV
10 20 30
70 80 90 100 110 120
pF1KE4 PQQTVAPQQQRRSLKEEECPAGSHRSEYTGACNPCTEGVDYTIASNNLPSCLLCTVCKSG
:::::::::::.:.: :::::::::::.:::::::::::::: :::: :::. ::::::
CCDS60 PQQTVAPQQQRHSFKGEECPAGSHRSEHTGACNPCTEGVDYTNASNNEPSCFPCTVCKSD
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE4 QTNKSSCTTTRDTVCQCEKGSFQDKNSPEMCRTCRTGCPRGMVKVSNCTPRSDIKCKNES
: .::::: ::::::::..:.:...::::::: : . :: : :.::::: .::.: .:
CCDS60 QKHKSSCTMTRDTVCQCKEGTFRNENSPEMCRKC-SRCPSGEVQVSNCTSWDDIQCVEEF
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE4 AASSTGKTPAAEETVTTILGMLASPYHYLIIIVVLVIILAVVVVGFSCRKKFISYLKGIC
.:..: .:::::::..: :
CCDS60 GANATVETPAAEETMNTSPGTPAPAAEETMNTSPGTPAPAAEETMTTSPGTPAPAAEETM
160 170 180 190 200 210
>>CCDS6036.1 TNFRSF10B gene_id:8795|Hs109|chr8 (411 aa)
initn: 1028 init1: 575 opt: 664 Z-score: 624.1 bits: 124.3 E(33420): 2e-28
Smith-Waterman score: 980; 49.6% identity (67.3% similar) in 339 aa overlap (5-342:5-307)
10 20 30 40 50
pF1KE4 MGLWGQSVPTASSARAGRYPGARTASGTRPWLLDPKILKFVVFIVA-VLLPVRVDSATIP
::..:.::.:: . :: : : :.:: :.. : .:..:: ::: : ..:: :
CCDS60 MEQRGQNAPAASGARKRHGPGPREARGARP---GPRVPKTLVLVVAAVLLLVSAESALIT
10 20 30 40 50
60 70 80 90 100 110
pF1KE4 RQDEVPQQTVAPQQQRRSLKEEECPAGSHRSEYTGACNPCTEGVDYTIASNNLPSCLLCT
.:: .::: .::::.: : .: :: : : :: : : : ::. :.: :: ::
CCDS60 QQDLAPQQRAAPQQKRSSPSEGLCPPGHHISEDGRDCISCKYGQDYSTHWNDLLFCLRCT
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE4 VCKSGQTNKSSCTTTRDTVCQCEKGSFQDKNSPEMCRTCRTGCPRGMVKVSNCTPRSDIK
: ::... : :::::.::::::.:.:....:::::: ::::::::::::..::: :::.
CCDS60 RCDSGEVELSPCTTTRNTVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPWSDIE
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE4 CKNESAASSTGKTPAAEETVTTILGMLASPYHYLIIIVVLVIILAVVVVGFSCRKKFISY
: .. .. :.: . ....:.:.:: : :: . :
CCDS60 CVHKESG--------------IIIG---------VTVAAVVLIVAVFVCKSLLWKKVLPY
180 190 200 210
240 250 260 270 280 290
pF1KE4 LKGICSGGGGGPERVHRVLFRRRSCPSRVPGAEDNARNETLSNRYLQPTQVSEQEIQGQE
:::::::::: :::: : :. ::::::. :: .: :::::: :::.. ::
CCDS60 LKGICSGGGGDPERVDR--------SSQRPGAEDNVLNEIVS--ILQPTQVPEQEMEVQE
220 230 240 250 260
300 310 320 330 340 350
pF1KE4 LAELTGVTVESPEEPQRLLEQAEAEGCQRRRLLVPVNDADSADISTLLDASATLEEGHAK
:: :::.. :: : ..::: :::: ::::::::.:..: ..
CCDS60 PAEPTGVNMLSPGESEHLLEPAEAERSQRRRLLVPANEGDPTETLRQCFDDFADLVPFDS
270 280 290 300 310 320
360 370 380
pF1KE4 ETIQDQLVGSEKLFYEEDEAGSATSCL
CCDS60 WEPLMRKLGLMDNEIKVAKAEAAGHRDTLYTMLIKWVNKTGRDASVHTLLDALETLGERL
330 340 350 360 370 380
>>CCDS6039.1 TNFRSF10A gene_id:8797|Hs109|chr8 (468 aa)
initn: 1043 init1: 517 opt: 632 Z-score: 593.8 bits: 118.9 E(33420): 9.6e-27
Smith-Waterman score: 918; 44.2% identity (57.8% similar) in 443 aa overlap (5-384:60-466)
10 20 30
pF1KE4 MGLWGQSVPTASSARAGRYPGARTASGTRPWLLD
:: :.: ::::: :: : : . : :
CCDS60 AAATPSKVWGSSAGRIEPRGGGRGALPTSMGQHGPSAR-ARAGRAPGPRPAREASPRLRV
30 40 50 60 70 80
40 50 60 70 80 90
pF1KE4 PKILKFVVFIVAVLLPVRVDSA-TIPRQDEVPQQTVAPQQQRRSLKEEECPAGSHRSEYT
: .:::: :.::: : .:: :: .: :... :: ..: : :: ::::::.
CCDS60 HKTFKFVV--VGVLLQVVPSSAATIKLHD----QSIGTQQWEHSPLGELCPPGSHRSEHP
90 100 110 120 130 140
100 110 120 130 140 150
pF1KE4 GACNPCTEGVDYTIASNNLPSCLLCTVCKSGQTNKSSCTTTRDTVCQCEKGSFQDKNSPE
:::: ::::: :: ::::: .:: ::.::: . ..: :::::.:.:::. :.:.. :: :
CCDS60 GACNRCTEGVGYTNASNNLFACLPCTACKSDEEERSPCTTTRNTACQCKPGTFRNDNSAE
150 160 170 180 190 200
160 170 180 190 200 210
pF1KE4 MCRTCRTGCPRGMVKVSNCTPRSDIKCKNESAASSTGKTPAAEETVTTILGMLASPYHYL
::: : :::::::::..::: :::.: .. :..:.. ..
CCDS60 MCRKCSRGCPRGMVKVKDCTPWSDIECVHKE--SGNGHNI------------------WV
210 220 230 240
220 230 240 250 260 270
pF1KE4 IIIVVLVIILAVVVVGFSCRKKFISYLKGICSGGGGGPERVHRVLFRRRSCPSRVPGAED
:..:.::. : .:.: . : : :: :: :. . :: : : . : :::::
CCDS60 ILVVTLVVPLLLVAVLIVC--------CCIGSGCGGDPKCMDRVCFWRLGL-LRGPGAED
250 260 270 280 290
280 290 300 310 320 330
pF1KE4 NARNETLSNRYLQPTQVSEQEIQGQELAELTGVTVESPEEPQRLLEQAEAEGCQRRRLLV
::.:: ::: : ::::....:: :.::::::.:: : : :: ::::: :::::::
CCDS60 NAHNEILSNADSLSTFVSEQQMESQEPADLTGVTVQSPGEAQCLLGPAEAEGSQRRRLLV
300 310 320 330 340 350
pF1KE4 PVNDAD------------------------------------------------------
:.: ::
CCDS60 PANGADPTETLMLFFDKFANIVPFDSWDQLMRQLDLTKNEIDVVRAGTAGPGDALYAMLM
360 370 380 390 400 410
340 350 360 370 380
pF1KE4 --------SADISTLLDASATLEEGHAKETIQDQLVGSEKLFYEEDEAGSATSCL
.:.: ::::: .:: ::.: ::: :: : :..: :: .:::.:
CCDS60 KWVNKTGRNASIHTLLDALERMEERHAREKIQDLLVDSGKFIYLEDGTGSAVSLE
420 430 440 450 460
386 residues in 1 query sequences
18921897 residues in 33420 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Oct 24 21:41:35 2019 done: Thu Oct 24 21:41:36 2019
Total Scan time: 1.570 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]