Result of FASTA (omim) for
pFN21AE1706
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1706, 211 aa
1>>>pF1KE1706 211 - 211 aa - 211 aa
Library: /omim/omim.rfq.tfa
65951994 residues in 93482 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9649+/-0.000257; mu= 16.2520+/- 0.016
mean_var=69.3464+/-14.261, 0's: 0 Z-trim(120.1): 90 B-trim: 2142 in 2/53
Lambda= 0.154015
statistics sampled from 36467 (36565) to 36467 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.759), E-opt: 0.2 (0.391), width: 16
Scan time: 3.060
The best scores are: opt bits E(93482)
NP_062825 (OMIM: 605558,615721) fibroblast growth ( 211) 1439 327.9 8.4e-90
NP_002001 (OMIM: 600921,612961) fibroblast growth ( 208) 995 229.2 4.2e-60
NP_003859 (OMIM: 300827,309630,309630) fibroblast ( 207) 920 212.5 4.3e-55
XP_011533298 (OMIM: 600921,612961) fibroblast grow ( 158) 719 167.8 9.7e-42
NP_004106 (OMIM: 601515,609307) fibroblast growth ( 247) 415 100.4 3e-21
NP_001308865 (OMIM: 601515,609307) fibroblast grow ( 184) 413 99.8 3.2e-21
NP_001308861 (OMIM: 601515,609307) fibroblast grow ( 184) 413 99.8 3.2e-21
NP_001308873 (OMIM: 601515,609307) fibroblast grow ( 184) 413 99.8 3.2e-21
NP_001308870 (OMIM: 601515,609307) fibroblast grow ( 185) 413 99.8 3.2e-21
NP_001308867 (OMIM: 601515,609307) fibroblast grow ( 187) 413 99.8 3.3e-21
NP_001308869 (OMIM: 601515,609307) fibroblast grow ( 187) 413 99.8 3.3e-21
NP_001308862 (OMIM: 601515,609307) fibroblast grow ( 187) 413 99.8 3.3e-21
NP_001308876 (OMIM: 601515,609307) fibroblast grow ( 200) 413 99.9 3.4e-21
NP_001308874 (OMIM: 601515,609307) fibroblast grow ( 213) 413 99.9 3.6e-21
NP_001308877 (OMIM: 601515,609307) fibroblast grow ( 213) 413 99.9 3.6e-21
NP_787125 (OMIM: 601515,609307) fibroblast growth ( 252) 413 99.9 4.1e-21
NP_004455 (OMIM: 165190,190330) fibroblast growth ( 268) 408 98.9 9.2e-21
NP_065688 (OMIM: 605831) fibroblast growth factor ( 170) 402 97.4 1.6e-20
XP_005248321 (OMIM: 149730,180920,602115) fibrobla ( 208) 401 97.2 2.2e-20
NP_004456 (OMIM: 149730,180920,602115) fibroblast ( 208) 401 97.2 2.2e-20
NP_001132970 (OMIM: 300070) fibroblast growth fact ( 199) 398 96.5 3.4e-20
NP_378668 (OMIM: 300070) fibroblast growth factor ( 192) 394 95.6 6.2e-20
NP_001132974 (OMIM: 300070) fibroblast growth fact ( 226) 394 95.7 7e-20
NP_001132973 (OMIM: 300070) fibroblast growth fact ( 226) 394 95.7 7e-20
NP_004105 (OMIM: 300070) fibroblast growth factor ( 245) 394 95.7 7.5e-20
NP_001132972 (OMIM: 300070) fibroblast growth fact ( 255) 394 95.7 7.7e-20
XP_005262456 (OMIM: 300070) fibroblast growth fact ( 255) 394 95.7 7.7e-20
XP_024308120 (OMIM: 300070) fibroblast growth fact ( 266) 394 95.7 7.9e-20
XP_005247284 (OMIM: 601513,617166) fibroblast grow ( 207) 390 94.8 1.2e-19
XP_006713601 (OMIM: 601513,617166) fibroblast grow ( 178) 385 93.6 2.3e-19
NP_004104 (OMIM: 601513,617166) fibroblast growth ( 181) 385 93.6 2.4e-19
NP_066360 (OMIM: 601513,617166) fibroblast growth ( 243) 385 93.7 3e-19
NP_002000 (OMIM: 148180) fibroblast growth factor ( 194) 377 91.9 8.6e-19
NP_004103 (OMIM: 601514) fibroblast growth factor ( 225) 373 91.0 1.8e-18
NP_001290389 (OMIM: 601514) fibroblast growth fact ( 166) 359 87.8 1.2e-17
NP_066276 (OMIM: 134921) fibroblast growth factor ( 208) 348 85.4 7.9e-17
NP_001998 (OMIM: 164980) fibroblast growth factor ( 206) 347 85.2 9.1e-17
NP_001308863 (OMIM: 601515,609307) fibroblast grow ( 163) 344 84.5 1.2e-16
NP_001308878 (OMIM: 601515,609307) fibroblast grow ( 163) 344 84.5 1.2e-16
NP_001308864 (OMIM: 601515,609307) fibroblast grow ( 163) 344 84.5 1.2e-16
NP_001308872 (OMIM: 601515,609307) fibroblast grow ( 163) 344 84.5 1.2e-16
NP_001308875 (OMIM: 601515,609307) fibroblast grow ( 163) 344 84.5 1.2e-16
NP_001308860 (OMIM: 601515,609307) fibroblast grow ( 163) 344 84.5 1.2e-16
NP_001308871 (OMIM: 601515,609307) fibroblast grow ( 163) 344 84.5 1.2e-16
XP_024309163 (OMIM: 601513,617166) fibroblast grow ( 157) 343 84.2 1.4e-16
NP_001138406 (OMIM: 131220) fibroblast growth fact ( 155) 328 80.9 1.4e-15
NP_001244134 (OMIM: 131220) fibroblast growth fact ( 155) 328 80.9 1.4e-15
NP_001138407 (OMIM: 131220) fibroblast growth fact ( 155) 328 80.9 1.4e-15
NP_001341880 (OMIM: 131220) fibroblast growth fact ( 155) 328 80.9 1.4e-15
NP_001341885 (OMIM: 131220) fibroblast growth fact ( 155) 328 80.9 1.4e-15
>>NP_062825 (OMIM: 605558,615721) fibroblast growth fact (211 aa)
initn: 1439 init1: 1439 opt: 1439 Z-score: 1733.9 bits: 327.9 E(93482): 8.4e-90
Smith-Waterman score: 1439; 100.0% identity (100.0% similar) in 211 aa overlap (1-211:1-211)
10 20 30 40 50 60
pF1KE1 MAPLAEVGGFLGGLEGLGQQVGSHFLLPPAGERPPLLGERRSAAERSARGGPGAAQLAHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_062 MAPLAEVGGFLGGLEGLGQQVGSHFLLPPAGERPPLLGERRSAAERSARGGPGAAQLAHL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 HGILRRRQLYCRTGFHLQILPDGSVQGTRQDHSLFGILEFISVAVGLVSIRGVDSGLYLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_062 HGILRRRQLYCRTGFHLQILPDGSVQGTRQDHSLFGILEFISVAVGLVSIRGVDSGLYLG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 MNDKGELYGSEKLTSECIFREQFEENWYNTYSSNIYKHGDTGRRYFVALNKDGTPRDGAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_062 MNDKGELYGSEKLTSECIFREQFEENWYNTYSSNIYKHGDTGRRYFVALNKDGTPRDGAR
130 140 150 160 170 180
190 200 210
pF1KE1 SKRHQKFTHFLPRPVDPERVPELYKDLLMYT
:::::::::::::::::::::::::::::::
NP_062 SKRHQKFTHFLPRPVDPERVPELYKDLLMYT
190 200 210
>>NP_002001 (OMIM: 600921,612961) fibroblast growth fact (208 aa)
initn: 996 init1: 951 opt: 995 Z-score: 1200.8 bits: 229.2 E(93482): 4.2e-60
Smith-Waterman score: 995; 70.3% identity (89.5% similar) in 209 aa overlap (1-208:1-205)
10 20 30 40 50
pF1KE1 MAPLAEVGGFLGGLEGLGQQVGSHFLLPPAGERPPLLGERRSAAERSARG-GPGAAQLAH
::::.:::...: ... :. .:: . : ::... . .: .. ::....: :
NP_002 MAPLGEVGNYFGVQDAV--PFGNVPVLPV--DSPVLLSDHLGQSEAGGLPRGPAVTDLDH
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 LHGILRRRQLYCRTGFHLQILPDGSVQGTRQDHSLFGILEFISVAVGLVSIRGVDSGLYL
:.::::::::::::::::.:.:.:..::::.::: ::::::::.::::::::::::::::
NP_002 LKGILRRRQLYCRTGFHLEIFPNGTIQGTRKDHSRFGILEFISIAVGLVSIRGVDSGLYL
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 GMNDKGELYGSEKLTSECIFREQFEENWYNTYSSNIYKHGDTGRRYFVALNKDGTPRDGA
:::.:::::::::::.::.::::::::::::::::.::: ::::::.::::::::::.:.
NP_002 GMNEKGELYGSEKLTQECVFREQFEENWYNTYSSNLYKHVDTGRRYYVALNKDGTPREGT
120 130 140 150 160 170
180 190 200 210
pF1KE1 RSKRHQKFTHFLPRPVDPERVPELYKDLLMYT
:.::::::::::::::::..:::::::.:
NP_002 RTKRHQKFTHFLPRPVDPDKVPELYKDILSQS
180 190 200
>>NP_003859 (OMIM: 300827,309630,309630) fibroblast grow (207 aa)
initn: 908 init1: 861 opt: 920 Z-score: 1110.8 bits: 212.5 E(93482): 4.3e-55
Smith-Waterman score: 920; 63.9% identity (86.1% similar) in 208 aa overlap (4-210:1-206)
10 20 30 40 50
pF1KE1 MAPLAEVGGFLGGLEGLGQQVGSHFLLPPAGERPPLLGERRSAAE-RSARGGPGAAQLAH
.::::: ...:. . .: . : .. : .:.:: . : . ::.: ...::
NP_003 MAEVGGVFASLDWDLHGFSSSLGNVPLADSPGFLNERLGQIEGKLQRGSP--TDFAH
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 LHGILRRRQLYCRTGFHLQILPDGSVQGTRQDHSLFGILEFISVAVGLVSIRGVDSGLYL
:.::::::::::::::::.:.:.:.:.:::.::: ::::::::.::::.:::::::::::
NP_003 LKGILRRRQLYCRTGFHLEIFPNGTVHGTRHDHSRFGILEFISLAVGLISIRGVDSGLYL
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 GMNDKGELYGSEKLTSECIFREQFEENWYNTYSSNIYKHGDTGRRYFVALNKDGTPRDGA
:::..::::::.::: ::.:::::::::::::.:..:::.:. :.:.:::::::.::.:
NP_003 GMNERGELYGSKKLTRECVFREQFEENWYNTYASTLYKHSDSERQYYVALNKDGSPREGY
120 130 140 150 160 170
180 190 200 210
pF1KE1 RSKRHQKFTHFLPRPVDPERVPELYKDLLMYT
:.:::::::::::::::: ..: . .::. :
NP_003 RTKRHQKFTHFLPRPVDPSKLPSMSRDLFHYR
180 190 200
>>XP_011533298 (OMIM: 600921,612961) fibroblast growth f (158 aa)
initn: 709 init1: 709 opt: 719 Z-score: 871.0 bits: 167.8 E(93482): 9.7e-42
Smith-Waterman score: 719; 78.5% identity (91.9% similar) in 135 aa overlap (79-208:21-155)
50 60 70 80 90 100
pF1KE1 RGGPGAAQLAHLHGILRRRQLYCRTGFHLQILPDGS---VQGTRQDHSL--FGILEFISV
. : :. ..: . ::: .:::::::.
XP_011 MRTAAGYSGSIETVKQKARPLTPRGQRKVLSGKWHLHSLDALGILEFISI
10 20 30 40 50
110 120 130 140 150 160
pF1KE1 AVGLVSIRGVDSGLYLGMNDKGELYGSEKLTSECIFREQFEENWYNTYSSNIYKHGDTGR
:::::::::::::::::::.:::::::::::.::.::::::::::::::::.::: ::::
XP_011 AVGLVSIRGVDSGLYLGMNEKGELYGSEKLTQECVFREQFEENWYNTYSSNLYKHVDTGR
60 70 80 90 100 110
170 180 190 200 210
pF1KE1 RYFVALNKDGTPRDGARSKRHQKFTHFLPRPVDPERVPELYKDLLMYT
::.::::::::::.:.:.::::::::::::::::..:::::::.:
XP_011 RYYVALNKDGTPREGTRTKRHQKFTHFLPRPVDPDKVPELYKDILSQS
120 130 140 150
>>NP_004106 (OMIM: 601515,609307) fibroblast growth fact (247 aa)
initn: 420 init1: 399 opt: 415 Z-score: 503.3 bits: 100.4 E(93482): 3e-21
Smith-Waterman score: 415; 42.4% identity (72.2% similar) in 151 aa overlap (56-204:64-212)
30 40 50 60 70 80
pF1KE1 LLPPAGERPPLLGERRSAAERSARGGPGAAQLAHLHGILRRRQLYCRTGFHLQILPDGSV
: .:.::. : :::: :..::. :::..
NP_004 SKNRGLCNGNLVDIFSKVRIFGLKKRRLRRQDPQLKGIVTR--LYCRQGYYLQMHPDGAL
40 50 60 70 80 90
90 100 110 120 130 140
pF1KE1 QGTRQDHSLFGILEFISVAVGLVSIRGVDSGLYLGMNDKGELYGSEKLTSECIFREQFEE
.::..: . ....: :.. .:.:.:: .:::..:: .: :: :: .: :: :.:. :
NP_004 DGTKDDSTNSTLFNLIPVGLRVVAIQGVKTGLYIAMNGEGYLYPSELFTPECKFKESVFE
100 110 120 130 140 150
150 160 170 180 190 200
pF1KE1 NWYNTYSSNIYKHGDTGRRYFVALNKDGTPRDGARSKRHQKFTHFLPRPVDPE--RVPEL
:.: ::: .:.. ..:: .:..:::.: : : :. . .::::.:.. : : :
NP_004 NYYVIYSSMLYRQQESGRAWFLGLNKEGQAMKGNRVKKTKPAAHFLPKPLEVAMYREPSL
160 170 180 190 200 210
210
pF1KE1 YKDLLMYT
.
NP_004 HDVGETVPKPGVTPSKSTSASAIMNGGKPVNKSKTT
220 230 240
>>NP_001308865 (OMIM: 601515,609307) fibroblast growth f (184 aa)
initn: 415 init1: 399 opt: 413 Z-score: 502.7 bits: 99.8 E(93482): 3.2e-21
Smith-Waterman score: 413; 42.6% identity (73.0% similar) in 148 aa overlap (59-204:4-149)
30 40 50 60 70 80
pF1KE1 PAGERPPLLGERRSAAERSARGGPGAAQLAHLHGILRRRQLYCRTGFHLQILPDGSVQGT
.:.::. : :::: :..::. :::...::
NP_001 MHPQLKGIVTR--LYCRQGYYLQMHPDGALDGT
10 20 30
90 100 110 120 130 140
pF1KE1 RQDHSLFGILEFISVAVGLVSIRGVDSGLYLGMNDKGELYGSEKLTSECIFREQFEENWY
..: . ....: :.. .:.:.:: .:::..:: .: :: :: .: :: :.:. ::.:
NP_001 KDDSTNSTLFNLIPVGLRVVAIQGVKTGLYIAMNGEGYLYPSELFTPECKFKESVFENYY
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE1 NTYSSNIYKHGDTGRRYFVALNKDGTPRDGARSKRHQKFTHFLPRPVDPE--RVPELYKD
::: .:.. ..:: .:..:::.: : : :. . .::::.:.. : : :.
NP_001 VIYSSMLYRQQESGRAWFLGLNKEGQAMKGNRVKKTKPAAHFLPKPLEVAMYREPSLHDV
100 110 120 130 140 150
210
pF1KE1 LLMYT
NP_001 GETVPKPGVTPSKSTSASAIMNGGKPVNKSKTT
160 170 180
>>NP_001308861 (OMIM: 601515,609307) fibroblast growth f (184 aa)
initn: 415 init1: 399 opt: 413 Z-score: 502.7 bits: 99.8 E(93482): 3.2e-21
Smith-Waterman score: 413; 42.6% identity (73.0% similar) in 148 aa overlap (59-204:4-149)
30 40 50 60 70 80
pF1KE1 PAGERPPLLGERRSAAERSARGGPGAAQLAHLHGILRRRQLYCRTGFHLQILPDGSVQGT
.:.::. : :::: :..::. :::...::
NP_001 MHPQLKGIVTR--LYCRQGYYLQMHPDGALDGT
10 20 30
90 100 110 120 130 140
pF1KE1 RQDHSLFGILEFISVAVGLVSIRGVDSGLYLGMNDKGELYGSEKLTSECIFREQFEENWY
..: . ....: :.. .:.:.:: .:::..:: .: :: :: .: :: :.:. ::.:
NP_001 KDDSTNSTLFNLIPVGLRVVAIQGVKTGLYIAMNGEGYLYPSELFTPECKFKESVFENYY
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE1 NTYSSNIYKHGDTGRRYFVALNKDGTPRDGARSKRHQKFTHFLPRPVDPE--RVPELYKD
::: .:.. ..:: .:..:::.: : : :. . .::::.:.. : : :.
NP_001 VIYSSMLYRQQESGRAWFLGLNKEGQAMKGNRVKKTKPAAHFLPKPLEVAMYREPSLHDV
100 110 120 130 140 150
210
pF1KE1 LLMYT
NP_001 GETVPKPGVTPSKSTSASAIMNGGKPVNKSKTT
160 170 180
>>NP_001308873 (OMIM: 601515,609307) fibroblast growth f (184 aa)
initn: 415 init1: 399 opt: 413 Z-score: 502.7 bits: 99.8 E(93482): 3.2e-21
Smith-Waterman score: 413; 42.6% identity (73.0% similar) in 148 aa overlap (59-204:4-149)
30 40 50 60 70 80
pF1KE1 PAGERPPLLGERRSAAERSARGGPGAAQLAHLHGILRRRQLYCRTGFHLQILPDGSVQGT
.:.::. : :::: :..::. :::...::
NP_001 MHPQLKGIVTR--LYCRQGYYLQMHPDGALDGT
10 20 30
90 100 110 120 130 140
pF1KE1 RQDHSLFGILEFISVAVGLVSIRGVDSGLYLGMNDKGELYGSEKLTSECIFREQFEENWY
..: . ....: :.. .:.:.:: .:::..:: .: :: :: .: :: :.:. ::.:
NP_001 KDDSTNSTLFNLIPVGLRVVAIQGVKTGLYIAMNGEGYLYPSELFTPECKFKESVFENYY
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE1 NTYSSNIYKHGDTGRRYFVALNKDGTPRDGARSKRHQKFTHFLPRPVDPE--RVPELYKD
::: .:.. ..:: .:..:::.: : : :. . .::::.:.. : : :.
NP_001 VIYSSMLYRQQESGRAWFLGLNKEGQAMKGNRVKKTKPAAHFLPKPLEVAMYREPSLHDV
100 110 120 130 140 150
210
pF1KE1 LLMYT
NP_001 GETVPKPGVTPSKSTSASAIMNGGKPVNKSKTT
160 170 180
>>NP_001308870 (OMIM: 601515,609307) fibroblast growth f (185 aa)
initn: 415 init1: 399 opt: 413 Z-score: 502.6 bits: 99.8 E(93482): 3.2e-21
Smith-Waterman score: 413; 42.6% identity (73.0% similar) in 148 aa overlap (59-204:5-150)
30 40 50 60 70 80
pF1KE1 PAGERPPLLGERRSAAERSARGGPGAAQLAHLHGILRRRQLYCRTGFHLQILPDGSVQGT
.:.::. : :::: :..::. :::...::
NP_001 MTDPQLKGIVTR--LYCRQGYYLQMHPDGALDGT
10 20 30
90 100 110 120 130 140
pF1KE1 RQDHSLFGILEFISVAVGLVSIRGVDSGLYLGMNDKGELYGSEKLTSECIFREQFEENWY
..: . ....: :.. .:.:.:: .:::..:: .: :: :: .: :: :.:. ::.:
NP_001 KDDSTNSTLFNLIPVGLRVVAIQGVKTGLYIAMNGEGYLYPSELFTPECKFKESVFENYY
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE1 NTYSSNIYKHGDTGRRYFVALNKDGTPRDGARSKRHQKFTHFLPRPVDPE--RVPELYKD
::: .:.. ..:: .:..:::.: : : :. . .::::.:.. : : :.
NP_001 VIYSSMLYRQQESGRAWFLGLNKEGQAMKGNRVKKTKPAAHFLPKPLEVAMYREPSLHDV
100 110 120 130 140 150
210
pF1KE1 LLMYT
NP_001 GETVPKPGVTPSKSTSASAIMNGGKPVNKSKTT
160 170 180
>>NP_001308867 (OMIM: 601515,609307) fibroblast growth f (187 aa)
initn: 415 init1: 399 opt: 413 Z-score: 502.6 bits: 99.8 E(93482): 3.3e-21
Smith-Waterman score: 413; 42.6% identity (73.0% similar) in 148 aa overlap (59-204:7-152)
30 40 50 60 70 80
pF1KE1 PAGERPPLLGERRSAAERSARGGPGAAQLAHLHGILRRRQLYCRTGFHLQILPDGSVQGT
.:.::. : :::: :..::. :::...::
NP_001 MPREDPQLKGIVTR--LYCRQGYYLQMHPDGALDGT
10 20 30
90 100 110 120 130 140
pF1KE1 RQDHSLFGILEFISVAVGLVSIRGVDSGLYLGMNDKGELYGSEKLTSECIFREQFEENWY
..: . ....: :.. .:.:.:: .:::..:: .: :: :: .: :: :.:. ::.:
NP_001 KDDSTNSTLFNLIPVGLRVVAIQGVKTGLYIAMNGEGYLYPSELFTPECKFKESVFENYY
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE1 NTYSSNIYKHGDTGRRYFVALNKDGTPRDGARSKRHQKFTHFLPRPVDPE--RVPELYKD
::: .:.. ..:: .:..:::.: : : :. . .::::.:.. : : :.
NP_001 VIYSSMLYRQQESGRAWFLGLNKEGQAMKGNRVKKTKPAAHFLPKPLEVAMYREPSLHDV
100 110 120 130 140 150
210
pF1KE1 LLMYT
NP_001 GETVPKPGVTPSKSTSASAIMNGGKPVNKSKTT
160 170 180
211 residues in 1 query sequences
65951994 residues in 93482 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Jun 19 14:26:50 2019 done: Wed Jun 19 14:26:50 2019
Total Scan time: 3.060 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]