Result of FASTA (ccds) for
pFN21AE2508
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2508, 454 aa
1>>>pF1KE2508 454 - 454 aa - 454 aa
Library: human.CCDS.faa
18921897 residues in 33420 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.7269+/-0.000981; mu= 7.9014+/- 0.059
mean_var=184.2888+/-38.963, 0's: 0 Z-trim(110.3): 80 B-trim: 553 in 1/52
Lambda= 0.094477
statistics sampled from 11625 (11695) to 11625 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.685), E-opt: 0.2 (0.35), width: 16
Scan time: 1.420
The best scores are: opt bits E(33420)
CCDS3995.1 PIK3R1 gene_id:5295|Hs109|chr5 ( 454) 3027 425.1 7.6e-119
CCDS3993.1 PIK3R1 gene_id:5295|Hs109|chr5 ( 724) 2788 392.7 6.8e-109
CCDS3994.1 PIK3R1 gene_id:5295|Hs109|chr5 ( 424) 2771 390.1 2.3e-108
CCDS56374.1 PIK3R1 gene_id:5295|Hs109|chr5 ( 361) 2379 336.7 2.5e-92
CCDS529.1 PIK3R3 gene_id:8503|Hs109|chr1 ( 461) 2374 336.1 4.8e-92
CCDS76155.1 PIK3R3 gene_id:110117499|Hs109|chr1 ( 507) 2260 320.6 2.4e-87
CCDS12371.1 PIK3R2 gene_id:5296|Hs109|chr19 ( 728) 2187 310.8 3.1e-84
CCDS76154.1 PIK3R3 gene_id:8503|Hs109|chr1 ( 402) 1388 201.6 1.2e-51
>>CCDS3995.1 PIK3R1 gene_id:5295|Hs109|chr5 (454 aa)
initn: 3027 init1: 3027 opt: 3027 Z-score: 2247.3 bits: 425.1 E(33420): 7.6e-119
Smith-Waterman score: 3027; 99.8% identity (100.0% similar) in 454 aa overlap (1-454:1-454)
10 20 30 40 50 60
pF1KE2 MYNTVWNMEDLDLEYAKTDINCGTDLMFYIEMDPPALPPKPPKPTTVANNGMNNNMSLQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 MYNTVWNMEDLDLEYAKTDINCGTDLMFYIEMDPPALPPKPPKPTTVANNGMNNNMSLQD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 AEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 AEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 GFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 GFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKLH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 KYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIE
.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 EYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 KFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 KFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPDL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 IQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 IQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSSN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 RNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 RNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYSS
370 380 390 400 410 420
430 440 450
pF1KE2 LKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR
::::::::::::::::::::::::::::::::::
CCDS39 LKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR
430 440 450
>>CCDS3993.1 PIK3R1 gene_id:5295|Hs109|chr5 (724 aa)
initn: 2786 init1: 2786 opt: 2788 Z-score: 2068.6 bits: 392.7 E(33420): 6.8e-109
Smith-Waterman score: 2788; 99.1% identity (99.5% similar) in 425 aa overlap (31-454:300-724)
10 20 30 40 50
pF1KE2 MYNTVWNMEDLDLEYAKTDINCGTDLMFYIEMDP-PALPPKPPKPTTVANNGMNNNMSLQ
: .: :::::::::::::::::::::::::
CCDS39 PMLFRFSAASSDNTENLIKVIEILISTEWNERQPAPALPPKPPKPTTVANNGMNNNMSLQ
270 280 290 300 310 320
60 70 80 90 100 110
pF1KE2 DAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 DAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGK
330 340 350 360 370 380
120 130 140 150 160 170
pF1KE2 YGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 YGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKL
390 400 410 420 430 440
180 190 200 210 220 230
pF1KE2 HKYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYI
:.::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 HEYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYI
450 460 470 480 490 500
240 250 260 270 280 290
pF1KE2 EKFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 EKFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPD
510 520 530 540 550 560
300 310 320 330 340 350
pF1KE2 LIQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 LIQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSS
570 580 590 600 610 620
360 370 380 390 400 410
pF1KE2 NRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 NRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYS
630 640 650 660 670 680
420 430 440 450
pF1KE2 SLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR
:::::::::::::::::::::::::::::::::::
CCDS39 SLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR
690 700 710 720
>>CCDS3994.1 PIK3R1 gene_id:5295|Hs109|chr5 (424 aa)
initn: 2771 init1: 2771 opt: 2771 Z-score: 2059.1 bits: 390.1 E(33420): 2.3e-108
Smith-Waterman score: 2771; 99.8% identity (100.0% similar) in 418 aa overlap (37-454:7-424)
10 20 30 40 50 60
pF1KE2 NMEDLDLEYAKTDINCGTDLMFYIEMDPPALPPKPPKPTTVANNGMNNNMSLQDAEWYWG
::::::::::::::::::::::::::::::
CCDS39 MHNLQTLPPKPPKPTTVANNGMNNNMSLQDAEWYWG
10 20 30
70 80 90 100 110 120
pF1KE2 DISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFSDPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 DISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFSDPL
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE2 TFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKLHKYNTQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::
CCDS39 TFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKLHEYNTQF
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE2 QEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIEKFKREG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 QEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIEKFKREG
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE2 NEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQLRKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 NEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQLRKT
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE2 RDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSSNRNKAEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 RDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSSNRNKAEN
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE2 LLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYSSLKELVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 LLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYSSLKELVL
340 350 360 370 380 390
430 440 450
pF1KE2 HYQHTSLVQHNDSLNVTLAYPVYAQQRR
::::::::::::::::::::::::::::
CCDS39 HYQHTSLVQHNDSLNVTLAYPVYAQQRR
400 410 420
>>CCDS56374.1 PIK3R1 gene_id:5295|Hs109|chr5 (361 aa)
initn: 2379 init1: 2379 opt: 2379 Z-score: 1771.3 bits: 336.7 E(33420): 2.5e-92
Smith-Waterman score: 2379; 99.7% identity (100.0% similar) in 361 aa overlap (94-454:1-361)
70 80 90 100 110 120
pF1KE2 YWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFS
::::::::::::::::::::::::::::::
CCDS56 MHGDYTLTLRKGGNNKLIKIFHRDGKYGFS
10 20 30
130 140 150 160 170 180
pF1KE2 DPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKLHKYN
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::.::
CCDS56 DPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKLHEYN
40 50 60 70 80 90
190 200 210 220 230 240
pF1KE2 TQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIEKFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 TQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIEKFK
100 110 120 130 140 150
250 260 270 280 290 300
pF1KE2 REGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 REGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQL
160 170 180 190 200 210
310 320 330 340 350 360
pF1KE2 RKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSSNRNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 RKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSSNRNK
220 230 240 250 260 270
370 380 390 400 410 420
pF1KE2 AENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYSSLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 AENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYSSLKE
280 290 300 310 320 330
430 440 450
pF1KE2 LVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR
:::::::::::::::::::::::::::::::
CCDS56 LVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR
340 350 360
>>CCDS529.1 PIK3R3 gene_id:8503|Hs109|chr1 (461 aa)
initn: 1576 init1: 1576 opt: 2374 Z-score: 1766.2 bits: 336.1 E(33420): 4.8e-92
Smith-Waterman score: 2374; 77.8% identity (92.5% similar) in 455 aa overlap (1-451:1-455)
10 20 30 40 50
pF1KE2 MYNTVWNMEDLDLEYAKTDINCGTDLMFYIEMDPPALPPKPPKPTTVA-NNGM-NNNMSL
::::::.:. : .. .. . .:.:.::::::::::::::::: : : ::: ....::
CCDS52 MYNTVWSMDRDDADWREVMMPYSTELIFYIEMDPPALPPKPPKPMTSAVPNGMKDSSVSL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 QDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDG
::::::::::::::::.:::: :::::::::::::.::::::::::::::::::.::::
CCDS52 QDAEWYWGDISREEVNDKLRDMPDGTFLVRDASTKMQGDYTLTLRKGGNNKLIKIYHRDG
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE2 KYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKK
::::::::::.:::::::::..::::::::::::::.::::.:::::.::::::.:::::
CCDS52 KYGFSDPLTFNSVVELINHYHHESLAQYNPKLDVKLMYPVSRYQQDQLVKEDNIDAVGKK
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE2 LHKYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEY
:..:..:.::::.:::::::::::::::::::::::::::::::::::::.:::..::::
CCDS52 LQEYHSQYQEKSKEYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCHTQEQHSKEY
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE2 IEKFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKP
::.:.::::::::.::: ::::::::..:: ::. :::.:::.:: . :::::.::::::
CCDS52 IERFRREGNEKEIERIMMNYDKLKSRLGEIHDSKMRLEQDLKNQALDNREIDKKMNSIKP
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE2 DLIQLRKTRDQYLMWLTQKGVRQKKLNEWLG--NENTEDQYSLVEDDEDLPHHDEKTWNV
::::::: :::.:.::..::::::.:: ::: ::.....: . :.::.:::.::::: :
CCDS52 DLIQLRKIRDQHLVWLNHKGVRQKRLNVWLGIKNEDADENYFINEEDENLPHYDEKTWFV
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE2 GSSNRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYN
. :: .::.:: :: ::.::.:::::.::::::::.::::::::: .:: :::::::::
CCDS52 EDINRVQAEDLLYGKPDGAFLIRESSKKGCYACSVVADGEVKHCVIYSTARGYGFAEPYN
370 380 390 400 410 420
420 430 440 450
pF1KE2 LYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR
:::::::::::::.:::::::::::: :::::.::
CCDS52 LYSSLKELVLHYQQTSLVQHNDSLNVRLAYPVHAQMPSLCR
430 440 450 460
>>CCDS76155.1 PIK3R3 gene_id:110117499|Hs109|chr1 (507 aa)
initn: 1576 init1: 1576 opt: 2260 Z-score: 1681.7 bits: 320.6 E(33420): 2.4e-87
Smith-Waterman score: 2260; 78.2% identity (91.7% similar) in 435 aa overlap (21-451:67-501)
10 20 30 40
pF1KE2 MYNTVWNMEDLDLEYAKTDINCGTDLMFYIEMDPPALPPKPPKPTTVA-N
: :: . . : ::::::::: : :
CCDS76 CSRRRYQQGLRGRTASSAAINPATRAMGINNTHTDTTIVWIFPPQALPPKPPKPMTSAVP
40 50 60 70 80 90
50 60 70 80 90 100
pF1KE2 NGM-NNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNN
::: ....::::::::::::::::::.:::: :::::::::::::.:::::::::::::
CCDS76 NGMKDSSVSLQDAEWYWGDISREEVNDKLRDMPDGTFLVRDASTKMQGDYTLTLRKGGNN
100 110 120 130 140 150
110 120 130 140 150 160
pF1KE2 KLIKIFHRDGKYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVK
:::::.::::::::::::::.:::::::::..::::::::::::::.::::.:::::.::
CCDS76 KLIKIYHRDGKYGFSDPLTFNSVVELINHYHHESLAQYNPKLDVKLMYPVSRYQQDQLVK
160 170 180 190 200 210
170 180 190 200 210 220
pF1KE2 EDNIEAVGKKLHKYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQC
::::.::::::..:..:.::::.:::::::::::::::::::::::::::::::::::::
CCDS76 EDNIDAVGKKLQEYHSQYQEKSKEYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQC
220 230 240 250 260 270
230 240 250 260 270 280
pF1KE2 QTQERYSKEYIEKFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYRE
.:::..::::::.:.::::::::.::: ::::::::..:: ::. :::.:::.:: . ::
CCDS76 HTQEQHSKEYIERFRREGNEKEIERIMMNYDKLKSRLGEIHDSKMRLEQDLKNQALDNRE
280 290 300 310 320 330
290 300 310 320 330 340
pF1KE2 IDKRMNSIKPDLIQLRKTRDQYLMWLTQKGVRQKKLNEWLG--NENTEDQYSLVEDDEDL
:::.::::::::::::: :::.:.::..::::::.:: ::: ::.....: . :.::.:
CCDS76 IDKKMNSIKPDLIQLRKIRDQHLVWLNHKGVRQKRLNVWLGIKNEDADENYFINEEDENL
340 350 360 370 380 390
350 360 370 380 390 400
pF1KE2 PHHDEKTWNVGSSNRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTA
::.::::: : . :: .::.:: :: ::.::.:::::.::::::::.::::::::: .::
CCDS76 PHYDEKTWFVEDINRVQAEDLLYGKPDGAFLIRESSKKGCYACSVVADGEVKHCVIYSTA
400 410 420 430 440 450
410 420 430 440 450
pF1KE2 TGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR
::::::::::::::::::::::.:::::::::::: :::::.::
CCDS76 RGYGFAEPYNLYSSLKELVLHYQQTSLVQHNDSLNVRLAYPVHAQMPSLCR
460 470 480 490 500
>>CCDS12371.1 PIK3R2 gene_id:5296|Hs109|chr19 (728 aa)
initn: 2143 init1: 1514 opt: 2187 Z-score: 1625.9 bits: 310.8 E(33420): 3.1e-84
Smith-Waterman score: 2187; 76.2% identity (92.7% similar) in 424 aa overlap (31-450:296-718)
10 20 30 40 50
pF1KE2 MYNTVWNMEDLDLEYAKTDINCGTDLMFYIEMDPPALPPKPPK--P-TTVANNGMNNNMS
:. :::::::::: : .:: :: .. :
CCDS12 PGGAPDGSEPSPDFPALLVEKLLQEHLEEQEVAPPALPPKPPKAKPASTVLANG-GSPPS
270 280 290 300 310 320
60 70 80 90 100 110
pF1KE2 LQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRD
::::::::::::::::::::::: ::::::::::.:..:.:::::::::::::::.::::
CCDS12 LQDAEWYWGDISREEVNEKLRDTPDGTFLVRDASSKIQGEYTLTLRKGGNNKLIKVFHRD
330 340 350 360 370 380
120 130 140 150 160 170
pF1KE2 GKYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGK
:.::::.:::: :::.::::::.::::::: :::..::::::::::::.::::..::::
CCDS12 GHYGFSEPLTFCSVVDLINHYRHESLAQYNAKLDTRLLYPVSKYQQDQIVKEDSVEAVGA
390 400 410 420 430 440
180 190 200 210 220 230
pF1KE2 KLHKYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKE
.:. :. :.:.::::::.:::::::::::.:::::::::::::::::::: ::::. :::
CCDS12 QLKVYHQQYQDKSREYDQLYEEYTRTSQELQMKRTAIEAFNETIKIFEEQGQTQEKCSKE
450 460 470 480 490 500
240 250 260 270 280 290
pF1KE2 YIEKFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIK
:.:.:.:::::::.:::. : ..:::::.:: .:: .::..:. ::.. :::::::::.:
CCDS12 YLERFRREGNEKEMQRILLNSERLKSRIAEIHESRTKLEQQLRAQASDNREIDKRMNSLK
510 520 530 540 550 560
300 310 320 330 340 350
pF1KE2 PDLIQLRKTRDQYLMWLTQKGVRQKKLNEWLGNEN-TEDQYSLVEDDEDLPHHDEKTWNV
:::.:::: :::::.::::::.::::.::::: .: :::::.:.::..:::::.:.:: :
CCDS12 PDLMQLRKIRDQYLVWLTQKGARQKKINEWLGIKNETEDQYALMEDEDDLPHHEERTWYV
570 580 590 600 610 620
360 370 380 390 400 410
pF1KE2 GSSNRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYN
:. ::..::..: ::::::::.::::..:::::::::::..::::: .::::.:::::::
CCDS12 GKINRTQAEEMLSGKRDGTFLIRESSQRGCYACSVVVDGDTKHCVIYRTATGFGFAEPYN
630 640 650 660 670 680
420 430 440 450
pF1KE2 LYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR
::.:::::::::::.:::::::.:.::::.:: :
CCDS12 LYGSLKELVLHYQHASLVQHNDALTVTLAHPVRAPGPGPPPAAR
690 700 710 720
>>CCDS76154.1 PIK3R3 gene_id:8503|Hs109|chr1 (402 aa)
initn: 1982 init1: 1176 opt: 1388 Z-score: 1040.7 bits: 201.6 E(33420): 1.2e-51
Smith-Waterman score: 1964; 68.1% identity (80.9% similar) in 455 aa overlap (1-451:1-396)
10 20 30 40 50
pF1KE2 MYNTVWNMEDLDLEYAKTDINCGTDLMFYIEMDPPALPPKPPKPTTVA-NNGM-NNNMSL
::::::.:. : .. .. . .:.:.::::::::::::::::: : : ::: ....::
CCDS76 MYNTVWSMDRDDADWREVMMPYSTELIFYIEMDPPALPPKPPKPMTSAVPNGMKDSSVSL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 QDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDG
::::::::::::::::.:::: :::::::::::::.::::::::::::::::::.::::
CCDS76 QDAEWYWGDISREEVNDKLRDMPDGTFLVRDASTKMQGDYTLTLRKGGNNKLIKIYHRDG
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE2 KYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKK
::::::::::.:::::::::..::::::::::::::.::::.:::::.::::::.:::::
CCDS76 KYGFSDPLTFNSVVELINHYHHESLAQYNPKLDVKLMYPVSRYQQDQLVKEDNIDAVGKK
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE2 LHKYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEY
:..:..:.::::.:::::::::::::::::::::::::::::::::::::.:::..::::
CCDS76 LQEYHSQYQEKSKEYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCHTQEQHSKEY
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE2 IEKFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKP
::.:.::::::::.:
CCDS76 IERFRREGNEKEIER---------------------------------------------
250
300 310 320 330 340 350
pF1KE2 DLIQLRKTRDQYLMWLTQKGVRQKKLNEWLG--NENTEDQYSLVEDDEDLPHHDEKTWNV
::..::::::.:: ::: ::.....: . :.::.:::.::::: :
CCDS76 --------------WLNHKGVRQKRLNVWLGIKNEDADENYFINEEDENLPHYDEKTWFV
260 270 280 290 300
360 370 380 390 400 410
pF1KE2 GSSNRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYN
. :: .::.:: :: ::.::.:::::.::::::::.::::::::: .:: :::::::::
CCDS76 EDINRVQAEDLLYGKPDGAFLIRESSKKGCYACSVVADGEVKHCVIYSTARGYGFAEPYN
310 320 330 340 350 360
420 430 440 450
pF1KE2 LYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR
:::::::::::::.:::::::::::: :::::.::
CCDS76 LYSSLKELVLHYQQTSLVQHNDSLNVRLAYPVHAQMPSLCR
370 380 390 400
454 residues in 1 query sequences
18921897 residues in 33420 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Oct 24 21:39:44 2019 done: Thu Oct 24 21:39:44 2019
Total Scan time: 1.420 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]